Hub : Genes

LOC108352728

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver intron excision ratio chr14_20404477_20405784 0.81 0.02 0.0e+00 0.44 0.42 0.45 0.46 8.6e-53 1.4e-49 7.7e-56 4.6e-56
2 Liver intron excision ratio chr14_20405906_20406423 0.73 0.07 0.0e+00 0.28 0.28 0.3 0.3 3.5e-31 1.2e-30 1.7e-33 4.0e-33
3 Liver intron excision ratio chr14_20402624_20404330 0.8 0.03 0.0e+00 0.43 0.42 0.44 0.44 2.5e-51 8.4e-50 8.9e-54 4.4e-54
4 Liver intron excision ratio chr14_20402624_20406423 0.78 0.03 0.0e+00 0.41 0.42 0.43 0.43 7.9e-49 1.3e-49 2.7e-51 2.5e-51
5 Liver isoform ratio XR_005493198.1 0.49 0.17 5.6e-17 0.17 0.12 0.13 0.16 3.5e-18 5.0e-13 1.2e-14 5.7e-17
6 Liver intron excision ratio chr14_20397163_20402480 0.85 0.02 0.0e+00 0.41 0.39 0.41 0.4 4.0e-48 5.0e-46 2.3e-48 5.3e-48
7 Liver intron excision ratio chr14_20402664_20406423 0.85 0.02 0.0e+00 0.39 0.44 0.46 0.46 5.4e-46 4.1e-53 1.6e-56 3.7e-57
8 Liver mRNA stability LOC108352728 0.08 0.05 2.7e-09 0.08 0.06 0.08 0.08 1.7e-09 1.5e-07 1.3e-09 1.5e-09
9 Liver intron excision ratio chr14_20402664_20404330 0.78 0.04 0.0e+00 0.42 0.43 0.42 0.42 4.8e-50 2.7e-51 5.5e-51 8.0e-51
10 Liver isoform ratio XR_001841096.2 0.43 0.2 1.2e-15 0.16 0.1 0.12 0.14 4.8e-17 2.1e-11 7.7e-13 1.1e-15
11 Liver intron excision ratio chr14_20398111_20402480 0.35 0.42 4.2e-10 0.11 0.07 0.09 0.1 3.1e-12 6.9e-08 3.8e-10 2.9e-11
12 Liver gene expression LOC108352728 0.73 0.08 0.0e+00 0.57 0.57 0.6 0.6 3.2e-76 3.1e-76 2.5e-82 1.6e-82

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.20.40.4-0.40.4-0.4-0.20.4-0.40.40.70.4-0.3-0.7
Area under the delay curve0.00.00.10.3-0.20.20.00.3-0.1-0.20.10.1-0.30.30.2
BMI with tail1.34.45.62.0-2.42.1-2.0-2.02.1-2.22.02.22.0-2.0-2.2
BMI without tail0.00.00.1-0.1-0.2-0.10.10.2-0.20.1-0.20.3-0.20.20.1
Body weight0.00.00.2-0.1-0.2-0.10.00.2-0.0-0.1-0.10.3-0.20.3-0.4
Weight adjusted by age0.70.81.70.9-0.70.9-1.0-0.71.0-1.00.90.90.8-0.8-1.3
Bone surface0.00.10.2-0.30.5-0.30.20.3-0.30.2-0.20.1-0.20.3-0.1
Bone volume0.30.40.6-0.70.8-0.70.70.8-0.70.6-0.6-0.4-0.70.70.4
Breakpoint value in progressive ratio session0.30.30.4-0.50.4-0.50.50.7-0.50.4-0.5-0.6-0.60.60.4
Number of licking bursts0.00.10.30.2-0.10.1-0.20.10.1-0.20.10.5-0.20.0-0.4
Context. condit. distance diff. score0.20.31.0-0.50.9-0.40.30.4-0.50.6-0.3-1.0-0.20.20.5
Locomotion velocity, session 10.60.71.10.8-1.00.8-0.7-0.60.9-0.90.81.00.7-0.7-0.9
Locomotion distance, session 10.30.40.5-0.70.7-0.60.60.6-0.60.7-0.6-0.7-0.60.60.5
Locomotion velocity, session 20.20.20.3-0.40.5-0.40.40.4-0.40.5-0.5-0.5-0.30.30.4
Locomotion distance, session 20.30.40.6-0.60.6-0.70.60.8-0.60.6-0.6-0.5-0.80.80.4
Locomotion velocity, session 30.20.20.5-0.40.5-0.30.50.5-0.40.5-0.6-0.6-0.30.30.7
Locomotion distance, session 30.30.40.60.6-0.50.7-0.6-0.80.6-0.50.50.30.8-0.8-0.3
Stereotopy head waving bouts, day 30.20.20.40.5-0.60.4-0.4-0.00.5-0.60.50.60.2-0.2-0.6
Stereotopy head waving duration, day 30.20.31.1-0.40.3-0.40.51.0-0.30.2-0.4-0.2-0.80.70.0
Locomotion velocity, session 72.22.42.8-1.51.4-1.51.61.7-1.61.5-1.6-1.4-1.51.51.6
Locomotion distance, session 71.41.82.1-1.41.4-1.31.31.3-1.51.4-1.4-1.4-1.31.31.2
Stereotopy head waving bouts, day 70.20.20.30.5-0.40.4-0.4-0.30.5-0.50.50.50.3-0.4-0.5
Stereotopy head waving duration, day 70.30.30.50.6-0.70.6-0.5-0.50.7-0.70.60.60.4-0.5-0.5
Locomotion velocity, session 80.00.00.3-0.10.3-0.10.10.2-0.00.2-0.1-0.6-0.00.10.1
Locomotion distance, session 81.42.03.1-1.41.8-1.41.31.5-1.41.4-1.2-1.7-1.31.31.1
Degree of sensitization distance3.03.03.4-1.81.8-1.81.71.8-1.91.7-1.7-1.6-1.71.81.4
Degree of sensitization stereotypy0.30.30.70.6-0.50.6-0.6-0.80.6-0.50.60.50.7-0.7-0.3
Conditioned locomotion0.80.91.21.0-0.91.1-1.1-0.90.9-0.91.00.70.9-1.0-1.0
Cocaine response after cond. corrected0.30.40.5-0.60.6-0.60.60.5-0.60.7-0.6-0.7-0.50.50.7
Cocaine response after cond. not corrected0.40.50.7-0.70.8-0.70.70.6-0.70.8-0.7-0.7-0.60.50.7
Cocaine response before conditioning0.00.00.10.2-0.10.1-0.2-0.20.2-0.20.20.30.2-0.3-0.3
Saline control response0.60.81.1-0.91.0-0.90.90.7-0.91.0-0.9-1.0-0.70.81.0
Bone: connectivity density0.50.81.40.9-0.90.8-0.8-0.70.9-0.90.81.20.9-0.8-1.0
Bone: cortical apparent density0.10.20.60.4-0.80.4-0.1-0.40.5-0.40.20.40.4-0.40.0
Bone: cortical area0.71.11.4-1.01.0-1.11.11.0-1.11.0-1.1-0.7-1.21.11.0
Bone: cortical porosity2.42.63.11.6-1.41.6-1.6-1.51.6-1.51.61.51.7-1.7-1.6
Bone: cortical porosity3.03.33.71.8-1.71.8-1.8-1.71.8-1.81.91.81.9-1.8-1.9
Bone: cortical thickness0.20.40.80.7-0.70.5-0.6-0.70.5-0.60.60.90.5-0.5-0.6
Bone: cortical thickness0.00.00.10.20.00.2-0.2-0.10.1-0.10.10.20.2-0.30.1
Bone: cortical tissue density0.20.30.90.5-0.90.6-0.3-0.50.6-0.60.30.50.6-0.6-0.1
Condit. Reinf. active minus inactive responses0.91.01.61.0-1.11.0-1.1-1.31.0-0.90.91.11.0-1.0-0.9
Condit. Reinf. active-inactive response ratio3.03.23.61.8-1.81.8-1.9-1.71.8-1.81.81.91.7-1.8-1.9
Condit. Reinf. active responses0.00.00.1-0.0-0.1-0.1-0.0-0.3-0.10.10.00.2-0.00.10.1
Condit. Reinf. inactive responses1.72.02.6-1.41.4-1.51.41.1-1.51.5-1.4-1.3-1.41.41.6
Incentive salience index mean0.10.10.40.3-0.40.3-0.4-0.60.3-0.30.20.30.4-0.3-0.3
Condit. Reinf. lever presses0.00.00.10.0-0.00.0-0.0-0.3-0.0-0.00.00.0-0.00.1-0.1
Condit. Reinf. active minus inactive responses0.20.30.5-0.50.5-0.60.60.5-0.40.5-0.4-0.4-0.70.70.4
Condit. Reinf. active-inactive response ratio0.10.10.2-0.20.2-0.30.30.1-0.20.3-0.2-0.1-0.10.20.4
Condit. Reinf. active responses0.50.71.0-0.80.9-0.90.90.9-0.70.7-0.7-0.7-1.01.00.5
Condit. Reinf. inactive responses1.11.41.9-1.21.4-1.21.21.3-1.11.0-1.0-1.2-1.41.30.7
Condit. Reinf. lever presses0.30.40.8-0.60.9-0.70.60.4-0.70.8-0.6-0.7-0.50.50.8
Condit. Reinf. lever reinforcers received0.50.81.1-0.91.0-0.90.90.9-0.80.8-0.7-0.8-1.01.00.6
Conditioned reinforcement - actives0.10.10.20.2-0.10.3-0.4-0.50.2-0.20.40.00.4-0.3-0.2
Conditioned reinforcement - inactives0.20.30.8-0.50.6-0.40.50.2-0.40.6-0.4-0.8-0.20.20.9
Conditioned locomotion0.00.10.1-0.20.3-0.30.1-0.2-0.30.3-0.2-0.2-0.10.20.3
Patch foraging indifference point 0 sec0.30.40.6-0.60.6-0.50.80.7-0.50.6-0.8-0.8-0.60.60.7
Patch foraging indifference point AUC2.42.83.1-1.81.5-1.71.71.6-1.71.6-1.6-1.5-1.71.71.7
Delay disc. indifference point, 0s delay0.10.10.30.6-0.50.5-0.3-0.30.3-0.40.30.50.1-0.1-0.3
Delay disc. indifference point, 16s delay0.60.61.21.0-1.10.9-0.7-0.50.6-1.00.80.80.3-0.3-0.6
Delay disc. indifference point, 2s delay4.04.45.6-2.02.0-2.02.12.4-2.12.0-2.1-1.9-2.32.32.0
Delay disc. indifference point, 24s delay0.00.00.20.00.1-0.00.10.3-0.1-0.1-0.0-0.2-0.30.4-0.0
Delay disc. indifference point, 4s delay0.10.10.40.1-0.20.10.20.3-0.1-0.0-0.2-0.1-0.20.10.6
Delay disc. indifference point, 8s delay0.90.91.41.2-1.21.0-1.0-0.70.9-1.21.11.10.6-0.6-1.0
Indifference point function ln k0.81.11.21.1-0.91.1-1.1-1.01.1-1.01.00.91.1-1.1-1.1
Indifference point function log k0.81.11.21.1-0.91.1-1.1-1.01.1-1.01.00.91.1-1.1-1.1
Patch foraging total patch changes 0 sec0.30.40.6-0.60.6-0.50.80.7-0.50.6-0.8-0.8-0.60.50.8
Patch foraging total patch changes 12 sec0.91.11.5-1.10.9-1.11.11.1-1.11.0-1.0-1.0-1.21.20.9
Patch foraging total patch changes 18 sec0.00.00.00.1-0.20.1-0.0-0.10.2-0.20.20.20.1-0.10.0
Patch foraging total patch changes 24 sec0.80.91.1-1.01.0-0.91.01.0-1.00.9-0.8-1.0-1.01.00.9
Patch foraging total patch changes 6 sec1.42.12.4-1.51.4-1.51.61.4-1.41.4-1.5-1.5-1.41.41.5
Patch foraging time to switch 0 sec3.35.15.82.3-2.32.3-2.2-2.22.3-2.42.12.12.2-2.1-2.4
Patch foraging water rate 0 sec2.74.34.8-2.22.1-2.22.12.1-2.22.2-2.1-1.8-2.12.11.9
Patch foraging water rate 12 sec0.30.40.7-0.70.8-0.70.60.4-0.70.8-0.6-0.6-0.50.50.9
Patch foraging water rate 18 sec2.02.83.3-1.61.8-1.61.71.6-1.71.8-1.6-1.7-1.51.51.7
Patch foraging water rate 24 sec1.31.82.7-1.31.7-1.41.21.2-1.51.5-1.2-1.3-1.21.21.4
Patch foraging water rate 6 sec0.81.21.5-1.11.1-1.21.11.0-1.21.2-1.0-0.9-1.01.11.2
Seeking ratio, delayed vs. immediate footshock0.40.40.7-0.60.7-0.60.70.6-0.70.6-0.4-0.7-0.60.50.9
Distance traveled before self-admin0.70.81.0-1.01.0-0.90.90.8-0.80.9-0.9-0.9-0.80.90.7
Distance traveled after self-admin3.13.44.4-1.92.1-1.91.81.8-1.81.9-1.8-1.9-1.81.81.7
Extensor digitorum longus weight11.946.950.07.0-6.96.9-7.0-6.56.8-7.06.97.16.5-6.5-7.0
Bone: elastic displacement0.91.11.41.2-0.91.1-1.1-1.21.0-0.91.10.91.0-1.0-1.0
Bone: elastic work1.41.82.81.5-1.11.4-1.3-1.71.3-1.21.41.21.4-1.4-0.9
Bone: endosteal estimation3.06.57.5-2.62.7-2.62.62.6-2.52.6-2.6-2.7-2.42.42.3
Bone: endosteal perimeter0.81.72.1-1.31.4-1.41.31.4-1.31.3-1.3-1.1-1.41.31.1
Epididymis fat weight0.10.30.4-0.60.4-0.50.40.7-0.50.4-0.5-0.3-0.60.70.1
Delta time in closed arm before/after self-admin1.51.52.11.2-1.31.1-1.3-1.41.1-1.11.41.21.3-1.2-0.9
Delta time in open arm before/after self-admin1.31.31.8-1.21.1-1.11.31.3-0.91.0-1.3-1.0-1.21.11.0
Diff in mean of infusions in LGA sessions0.00.00.10.2-0.10.2-0.1-0.10.2-0.20.2-0.20.1-0.1-0.2
Delay discount exponential model param0.10.10.2-0.10.1-0.0-0.2-0.40.20.10.10.10.4-0.4-0.4
Extinction: sum of active levers before priming0.00.00.2-0.20.3-0.10.20.2-0.20.2-0.1-0.2-0.10.10.4
Active lever presses in extinction session 61.01.01.5-1.00.9-0.90.91.2-1.00.9-1.0-0.9-1.11.00.7
Bone: final force0.40.70.9-0.90.9-0.90.90.8-0.80.8-0.9-0.5-0.80.80.8
Bone: final moment0.30.50.7-0.70.7-0.80.70.6-0.80.8-0.8-0.4-0.60.60.8
Food consumed during 24 hour testing period2.02.43.1-1.61.8-1.51.41.6-1.61.7-1.4-1.5-1.51.41.4
Glucose1.52.32.6-1.51.5-1.51.51.5-1.51.5-1.5-1.6-1.51.51.3
Heart weight0.00.10.2-0.20.1-0.30.10.1-0.30.2-0.10.1-0.30.4-0.3
Delay discount hyperbolic model param0.20.20.50.2-0.20.3-0.5-0.70.5-0.20.40.40.7-0.7-0.7
Intermittent access intake day 1-15 change0.70.71.30.7-0.50.7-1.0-0.90.6-0.71.00.80.7-0.6-1.1
Intermittent access intake escalation0.20.20.60.3-0.10.3-0.6-0.60.3-0.30.70.30.4-0.3-0.8
Intermittent access intake escalation 20.30.30.5-0.60.7-0.60.40.4-0.60.6-0.3-0.6-0.50.60.3
Intermitt. access day 1 inactive lever presses0.50.51.5-0.70.8-0.50.70.8-0.60.7-0.6-1.2-0.60.50.8
Intermitt. access day 15 inactive lever presses1.31.51.8-1.21.3-1.11.21.2-1.21.2-1.1-1.3-1.21.11.3
Intermitt. access escalation Index1.91.72.11.4-1.31.3-1.3-1.21.3-1.41.31.41.2-1.1-1.4
Intermittent access day 1 total infusions0.10.10.10.3-0.20.3-0.2-0.30.3-0.30.30.10.4-0.40.0
Intermittent access day 15 total infusions0.00.00.1-0.00.20.0-0.1-0.1-0.10.10.2-0.20.10.0-0.0
Intermittent access terminal intake (last 3 days)0.40.40.7-0.70.8-0.60.50.4-0.70.7-0.4-0.8-0.50.60.6
Intermittent access total infusions0.00.00.00.00.10.1-0.1-0.20.00.00.2-0.10.1-0.10.1
Intermittent access day 1 locomotion0.00.00.10.00.00.1-0.0-0.10.00.00.1-0.20.1-0.10.3
Intermittent access day 15 total locomotion0.00.00.2-0.20.3-0.10.1-0.0-0.20.2-0.1-0.4-0.00.10.3
Intermittent access total locomotion0.10.10.20.3-0.20.2-0.3-0.40.2-0.20.30.10.4-0.3-0.0
Intermittent access standard deviation0.40.40.6-0.70.8-0.70.50.5-0.70.7-0.5-0.7-0.60.60.5
Left kidney weight0.82.22.7-1.61.6-1.61.41.4-1.71.6-1.4-1.4-1.51.51.3
Right kidney weight1.54.14.9-2.11.9-2.22.02.0-2.22.0-2.0-1.7-2.22.21.7
Cocaine induced anxiety0.00.00.10.0-0.10.0-0.00.10.0-0.10.00.3-0.10.1-0.2
Post-drug Anxiety0.00.00.1-0.0-0.20.00.00.10.0-0.1-0.10.1-0.0-0.00.2
Baseline Anxiety0.10.10.30.3-0.20.3-0.2-0.40.3-0.20.3-0.00.5-0.50.1
Tail length0.20.50.7-0.80.8-0.80.70.8-0.80.8-0.7-0.4-0.80.80.7
Length with tail1.34.95.4-2.32.3-2.32.22.2-2.22.2-2.2-2.0-2.32.31.9
Length without tail0.91.92.3-1.41.4-1.41.51.4-1.21.3-1.4-1.5-1.41.41.1
Times rat made contact with spout0.00.00.1-0.1-0.0-0.10.10.3-0.10.1-0.20.1-0.10.00.3
Lifetime Intake0.20.20.40.5-0.40.5-0.5-0.60.5-0.40.60.30.6-0.5-0.3
Liver weight, left1.52.42.9-1.51.3-1.51.61.6-1.61.5-1.7-1.5-1.51.51.7
Liver weight, right2.64.35.1-2.11.9-2.02.22.1-2.02.0-2.3-2.0-2.12.02.1
Locomotor activity1.21.92.7-1.51.6-1.41.31.3-1.41.4-1.3-1.3-1.31.41.0
Locomotor testing distance0.30.51.2-0.71.1-0.70.60.7-0.70.8-0.6-0.9-0.60.60.4
Locomotor testing rearing0.20.30.7-0.60.8-0.50.40.5-0.60.6-0.4-0.6-0.50.50.1
Locomotion in novel chamber0.00.00.0-0.10.00.00.10.10.00.0-0.20.1-0.10.0-0.1
Locomotion in novel chamber post-restriction0.40.40.8-0.70.5-0.60.80.7-0.60.6-0.8-0.4-0.70.50.9
Fecal boli incidents, locomotor time 12.42.63.61.8-1.61.7-1.6-1.61.6-1.71.71.91.5-1.5-1.3
Change in fecal boli incidents, locomotor task0.00.00.20.00.10.00.0-0.00.1-0.10.00.0-0.20.2-0.4
Time >=10cm from walls, locomotor time 13.43.44.01.8-1.71.9-1.8-2.01.9-1.92.01.91.7-1.6-1.8
Bouts of movement, locomotor time 10.91.01.30.8-1.00.9-1.0-1.01.0-1.00.81.11.0-1.0-1.1
Total resting periods, locomotor time 10.80.91.30.8-1.00.9-0.9-1.01.1-1.00.71.10.9-0.9-1.0
Rest time, locomotor task time 10.10.10.3-0.30.6-0.30.40.3-0.20.2-0.5-0.1-0.40.30.3
Distance moved, locomotor task time 10.00.00.10.0-0.10.0-0.00.3-0.10.00.1-0.20.10.0-0.1
Vertical activity count, locomotor time 11.01.12.3-1.00.7-1.01.01.5-1.21.0-0.9-0.9-1.01.10.9
Time >=10cm from walls, locomotor time 20.70.81.10.9-0.60.9-0.8-1.01.0-1.01.01.00.6-0.6-1.0
Bouts of movement, locomotor time 20.10.10.3-0.40.4-0.30.50.4-0.20.3-0.4-0.5-0.40.40.3
Total resting periods, locomotor time 20.10.10.2-0.40.3-0.20.40.2-0.10.2-0.4-0.4-0.30.30.2
Rest time, locomotor task time 20.30.30.9-0.71.0-0.60.60.2-0.40.5-0.7-0.7-0.50.50.2
Distance moved, locomotor task time 20.80.91.41.1-1.21.0-1.0-0.30.8-0.90.91.20.9-0.8-1.0
Vertical activity count, locomotor time 20.10.10.5-0.1-0.1-0.20.20.7-0.30.2-0.20.2-0.20.20.2
Light reinforcement 10.91.61.9-1.41.3-1.31.31.3-1.31.2-1.2-1.2-1.41.41.1
Light reinforcement 20.10.20.20.4-0.50.4-0.3-0.20.5-0.50.50.40.3-0.4-0.4
Bone: marrow area2.86.27.3-2.62.7-2.52.52.5-2.42.5-2.5-2.6-2.42.32.2
Bone: maximum diameter0.40.71.1-0.80.6-0.90.81.0-0.90.7-0.8-0.3-1.01.00.5
Bone: maximum force0.71.31.5-1.11.2-1.21.21.1-1.21.2-1.2-0.8-1.11.01.2
Bone: maximum moment0.71.21.6-1.11.1-1.21.11.0-1.21.2-1.2-0.8-1.00.91.3
Mean time between licks in bursts3.75.25.72.3-2.42.2-2.2-2.32.3-2.32.22.42.3-2.2-2.3
Mean num. licks in bursts0.10.10.9-0.30.2-0.10.30.1-0.30.4-0.3-0.60.10.00.9
Cd content in liver2.52.73.61.6-1.71.6-1.5-1.71.7-1.61.51.51.9-1.9-1.5
Co content in liver0.10.10.2-0.30.3-0.30.40.2-0.20.3-0.4-0.3-0.20.10.3
Cu content in liver1.01.21.4-1.11.0-1.11.11.1-1.11.1-1.2-1.1-1.11.01.0
Fe content in liver0.20.30.60.5-0.70.4-0.4-0.40.5-0.60.50.80.4-0.4-0.5
K content in liver1.71.72.3-1.51.2-1.41.51.0-1.21.3-1.5-1.5-1.11.11.2
Mg content in liver1.81.92.5-1.61.2-1.51.51.2-1.31.3-1.5-1.4-1.31.31.2
Mn content in liver0.30.30.7-0.60.6-0.50.40.7-0.50.4-0.5-0.5-0.90.70.1
Na content in liver0.80.81.1-1.00.7-0.91.00.9-0.90.8-1.0-0.7-1.01.00.8
Rb content in liver0.10.20.50.2-0.40.2-0.3-0.10.4-0.40.30.50.4-0.4-0.7
Se content in liver0.20.30.4-0.60.5-0.50.60.6-0.50.4-0.5-0.7-0.50.50.4
Sr content in liver0.20.20.30.6-0.30.6-0.5-0.10.4-0.50.60.60.0-0.0-0.4
Zn content in liver0.80.91.8-1.11.0-1.01.00.7-0.81.1-0.9-1.3-0.70.60.8
Bone: minimum diameter8.415.716.7-4.04.0-4.14.03.8-4.04.0-4.1-3.7-4.03.93.9
Time in familiar zone, hab. session 10.40.30.6-0.60.8-0.60.50.6-0.50.6-0.5-0.7-0.60.60.5
Time in novel zone, hab. session 11.31.32.11.1-1.41.2-1.1-1.21.1-1.11.01.21.2-1.2-0.8
Total zone transitions, hab. session 10.20.20.4-0.50.5-0.50.50.6-0.50.5-0.4-0.2-0.50.50.4
Total locomotion distance, hab. session 12.33.34.0-1.82.0-1.81.92.0-1.71.8-1.7-1.8-1.81.91.6
Locomotion velocity, hab. session 12.23.14.0-1.72.0-1.71.82.0-1.61.7-1.6-1.7-1.81.81.5
Time in familiar zone, hab. session 21.11.21.91.1-1.11.1-1.0-1.41.1-0.91.00.91.3-1.2-0.5
Time in novel zone, hab. session 20.60.61.2-0.80.6-0.80.71.1-0.80.7-0.8-0.5-1.00.90.3
Total zone transitions, hab. session 20.00.00.10.10.00.0-0.1-0.10.1-0.00.20.30.1-0.00.1
Total locomotion distance, hab. session 20.60.81.1-0.81.0-0.90.90.8-0.90.9-0.8-0.8-0.80.90.9
Locomotion velocity, hab. session 20.50.71.1-0.81.0-0.90.90.8-0.80.8-0.8-0.8-0.80.90.9
Novel to familiar place preference ratio0.20.20.3-0.40.2-0.40.50.5-0.40.3-0.5-0.1-0.50.50.4
Novelty place preference0.00.00.1-0.1-0.2-0.10.10.1-0.0-0.0-0.20.2-0.10.20.2
Time in novel zone, NPP test0.10.10.2-0.3-0.0-0.30.40.4-0.30.2-0.5-0.0-0.40.40.4
Total zone transitions, NPP test0.00.00.1-0.10.1-0.10.10.2-0.10.1-0.00.1-0.20.20.0
Total locomotion distance, NPP test0.10.10.3-0.40.6-0.40.40.4-0.30.4-0.3-0.3-0.30.30.3
Locomotion velocity, NPP test0.00.00.00.00.2-0.00.00.00.10.00.10.00.1-0.0-0.0
Intraocular pressure0.91.21.91.1-1.21.1-1.1-1.11.1-0.90.91.11.4-1.3-0.8
Delta distance traveled before/after self-admin0.40.40.6-0.60.7-0.60.60.8-0.70.6-0.6-0.7-0.70.70.6
Delta ambulatory time before/after self-admin0.10.10.1-0.20.3-0.20.20.3-0.30.2-0.2-0.3-0.30.20.4
Parametrial fat weight1.22.43.2-1.51.3-1.51.71.6-1.41.5-1.8-1.4-1.51.41.8
Pavlov. Cond. lever latency2.02.53.21.7-1.51.7-1.5-1.41.7-1.51.51.51.7-1.8-1.2
Pavlov. Cond. magazine entry latency0.00.00.1-0.10.2-0.10.00.0-0.00.10.1-0.1-0.00.10.0
Pavlov. Cond. change in total contacts0.40.50.7-0.80.6-0.80.70.5-0.80.7-0.6-0.7-0.60.80.4
Pavlov. Cond. index score0.60.71.1-1.00.9-0.90.80.8-0.90.8-0.7-0.8-0.91.00.6
Pavlov. Cond. latency score0.81.01.4-1.11.0-1.11.00.9-1.11.0-0.9-1.0-1.11.20.7
Pavlov. Cond. lever contacts2.22.53.2-1.71.5-1.71.61.4-1.71.6-1.5-1.5-1.71.81.3
Pavlov. Cond. magazine entry number0.00.00.1-0.10.2-0.10.20.2-0.10.2-0.3-0.2-0.20.10.3
Pavlov. Cond. intertrial magazine entries2.12.53.8-1.71.4-1.71.61.7-1.61.4-1.5-1.3-1.91.91.0
Pavlov. Cond. lever-magazine prob. diff.0.70.91.3-1.00.9-1.00.90.9-1.00.9-0.8-0.9-1.01.10.7
Pavlov. Cond. response bias0.60.70.9-0.90.8-0.90.80.8-0.90.8-0.7-0.8-0.80.90.7
Pavlov. Cond. lever latency0.10.20.2-0.40.1-0.40.40.5-0.40.3-0.5-0.4-0.40.40.3
Pavlov. Cond. magazine entry latency1.11.21.71.2-0.91.1-1.1-1.31.1-1.11.21.31.1-0.9-0.9
Pavlov. Cond. change in total contacts0.30.50.70.7-0.40.7-0.7-0.80.7-0.60.80.70.6-0.6-0.7
Pavlov. Cond. index score0.70.81.11.0-0.60.9-1.0-1.00.9-0.91.11.00.9-0.8-0.9
Pavlov. Cond. latency score1.01.31.71.2-0.81.1-1.2-1.31.1-1.11.31.21.1-1.0-1.1
Pavlov. Cond. lever contacts0.00.00.10.20.10.2-0.2-0.30.2-0.20.30.30.2-0.1-0.2
Pavlov. Cond. magazine entry number1.72.12.8-1.51.2-1.41.51.6-1.41.4-1.5-1.7-1.41.31.3
Pavlov. Cond. intertrial magazine entries2.73.54.7-1.91.6-1.91.92.2-1.91.8-1.9-1.8-2.01.91.6
Pavlov. Cond. lever-magazine prob. diff.0.50.60.90.9-0.50.8-0.9-0.90.8-0.80.90.90.7-0.7-0.8
Pavlov. Cond. response bias0.50.71.00.9-0.50.9-0.9-0.90.9-0.81.01.00.8-0.8-0.8
Time in closed arm before self-admin1.41.62.3-1.21.3-1.11.31.5-1.11.1-1.4-1.3-1.31.21.1
Time in closed arm after self-admin0.10.10.20.2-0.10.3-0.3-0.50.3-0.10.4-0.10.4-0.4-0.1
Time in open arm before self-admin0.30.30.60.6-0.40.4-0.8-0.70.3-0.40.70.50.5-0.3-0.6
Time in open arm after self-admin1.11.21.6-1.11.0-1.11.21.2-1.01.0-1.3-0.9-1.21.11.1
Bone: periosteal estimation1.94.04.4-2.12.1-2.12.12.0-2.02.0-2.0-1.8-2.02.01.8
Bone: periosteal perimeter0.91.51.8-1.21.3-1.41.31.2-1.31.2-1.2-0.9-1.31.31.1
Bone: post-yield work0.40.50.8-0.70.6-0.70.70.8-0.60.7-0.8-0.6-0.50.50.9
Progressive ratio test 1 active lever presses0.00.10.10.2-0.20.2-0.2-0.30.2-0.20.30.20.3-0.2-0.1
Progressive ratio test 1 breakpoint0.10.10.20.3-0.30.3-0.4-0.50.3-0.30.40.40.4-0.3-0.2
Progressive ratio test 1 inactive lever presses1.61.72.8-1.31.4-1.21.31.2-1.21.4-1.2-1.7-1.21.11.4
Progressive ratio test 2 active lever presses0.00.00.1-0.10.1-0.00.0-0.1-0.00.10.1-0.20.1-0.00.2
Progressive ratio test 2 breakpoint0.00.00.0-0.10.1-0.00.0-0.1-0.00.10.0-0.20.0-0.00.2
Progressive ratio test 2 inactive lever presses0.30.40.8-0.60.7-0.50.60.4-0.50.6-0.5-0.9-0.40.40.8
Incentive Sensitization - Responses0.00.00.10.1-0.10.2-0.2-0.20.2-0.20.2-0.10.2-0.2-0.1
Incentive Sensitization - Breakpoint0.00.00.1-0.00.00.1-0.1-0.10.0-0.00.1-0.20.0-0.10.0
Sum of active levers in priming session hrs 5-60.00.00.1-0.20.3-0.10.20.0-0.10.2-0.1-0.30.0-0.10.4
Progressive ratio0.30.40.70.6-0.50.6-0.6-0.40.5-0.70.70.60.5-0.4-0.8
Food seeking constrained by brief footshock0.50.60.90.8-0.80.7-0.7-0.90.8-0.80.70.80.9-0.8-0.5
Seeking ratio, punishment vs. effort0.10.20.5-0.40.2-0.40.40.1-0.30.5-0.5-0.4-0.20.20.7
Retroperitoneal fat weight0.72.32.8-1.71.2-1.61.61.6-1.51.4-1.6-1.1-1.71.71.2
Reaction time number correct0.10.10.2-0.30.3-0.40.00.2-0.50.2-0.00.3-0.40.5-0.0
Reaction time mean minus median1.11.41.91.2-1.41.2-1.1-1.21.2-1.21.01.31.2-1.2-0.8
Reaction time mean minus median AUC0.70.91.61.0-1.31.0-0.8-1.01.0-0.90.71.11.0-1.0-0.6
Reaction time num false alarms0.10.20.3-0.40.2-0.50.40.3-0.50.4-0.4-0.4-0.40.60.5
Reaction time num false alarms AUC0.00.00.10.1-0.40.0-0.1-0.10.0-0.10.10.10.10.00.1
Reaction time trials correct on left0.10.10.2-0.30.3-0.40.00.2-0.50.2-0.00.3-0.40.5-0.0
Reaction time trials on left0.10.10.2-0.20.2-0.4-0.00.1-0.40.20.00.3-0.30.4-0.0
Reaction time mean0.81.11.41.0-1.21.1-1.0-1.01.1-1.11.00.91.1-1.1-0.8
Reaction time mean AUC0.50.71.00.8-1.00.9-0.7-0.70.9-0.90.70.70.8-0.9-0.6
Median of all reaction times0.70.91.10.9-1.11.1-0.9-0.81.1-1.01.00.81.0-1.1-0.8
Reaction time omissions2.23.03.61.8-1.81.7-1.8-1.91.7-1.61.71.81.8-1.8-1.4
Reaction time false alarm rate0.00.00.10.1-0.40.20.0-0.10.2-0.1-0.0-0.20.2-0.10.1
Reaction time premature initiation rate0.10.10.3-0.40.3-0.20.40.4-0.20.3-0.4-0.5-0.40.20.5
Reaction time premature initiations0.20.30.5-0.70.5-0.60.50.6-0.60.5-0.5-0.4-0.70.60.7
Std. dev. reaction times0.60.81.20.9-1.10.9-0.8-0.91.0-0.90.80.91.0-1.0-0.6
Reaction time trials completed0.10.10.2-0.20.2-0.4-0.00.1-0.40.20.00.3-0.30.4-0.0
Reaction time trials AUC0.00.10.2-0.20.2-0.4-0.00.1-0.40.10.00.4-0.30.4-0.1
Run reversals in cocaine runway, females6.76.57.6-2.62.6-2.72.52.3-2.82.6-2.5-2.4-2.52.72.2
Run reversals in cocaine runway, males0.00.00.1-0.00.1-0.0-0.10.1-0.1-0.00.1-0.0-0.20.2-0.4
Latency to leave start box in cocaine runway0.80.81.8-0.90.9-0.81.11.0-0.80.9-0.9-0.6-0.80.71.4
Latency to leave start box in cocaine runway, F2.72.94.2-1.71.6-1.71.91.8-1.51.7-1.8-1.5-1.61.52.0
Latency to leave start box in cocaine runway, M0.70.61.10.8-0.70.8-0.8-0.70.8-0.80.91.00.7-0.8-0.7
Std. dev. time between licks in bursts0.20.31.10.5-0.30.5-0.5-0.20.6-0.60.50.40.1-0.3-1.1
Total sessions with >9 infusions2.72.93.31.8-1.61.7-1.8-1.71.7-1.71.81.61.8-1.7-1.7
Short access day 1 total inactive lever presses0.60.71.6-0.81.1-0.70.80.8-0.80.8-0.6-1.3-0.80.70.7
Short access day 10 total inactive lever presses0.40.51.1-0.60.9-0.60.70.6-0.70.8-0.6-1.0-0.50.50.8
Short access day 1 total infusions0.00.00.00.1-0.10.1-0.0-0.20.1-0.00.1-0.00.1-0.10.0
Short access day 10 total infusions1.21.31.81.2-1.01.2-1.1-1.31.2-1.11.20.91.3-1.3-0.7
Short access total infusions1.41.61.91.4-1.21.3-1.2-1.41.3-1.21.31.11.4-1.3-1.0
Short access day 1 locomotion0.00.00.00.0-0.00.0-0.1-0.20.1-0.10.10.20.10.0-0.2
Short access day 10 total locomotion0.40.40.70.7-0.80.7-0.6-0.80.7-0.60.60.40.8-0.7-0.3
Short access total locomotion0.90.91.21.0-1.00.9-1.0-1.10.9-0.91.00.91.0-0.9-0.7
One hour access (0.3 mA shock)0.10.10.10.3-0.10.3-0.2-0.30.3-0.20.20.10.4-0.40.2
Compulsive drug intake0.60.61.00.9-1.00.8-0.5-0.70.9-0.80.50.70.9-0.9-0.2
One hour access (shock baseline)0.00.00.1-0.20.3-0.20.10.1-0.20.2-0.0-0.2-0.10.20.2
Social response proportion0.30.30.9-0.60.4-0.50.70.5-0.50.5-0.6-0.7-0.50.41.0
Social responses0.60.81.0-0.90.8-0.90.90.9-1.00.9-0.8-1.0-0.90.90.9
Social time0.70.91.2-1.00.9-0.91.11.0-0.90.9-1.1-0.9-1.00.90.9
Soleus weight0.30.91.40.9-0.60.9-1.0-1.20.9-0.91.20.70.9-0.8-1.2
Bone: stiffness2.43.84.6-2.11.8-2.12.02.0-2.02.0-2.1-1.6-1.91.91.9
Tibialis anterior weight4.615.817.34.0-4.23.9-4.1-4.03.9-4.04.04.14.0-3.9-3.8
Time to tail flick, vehicle, before self-admin0.80.91.1-0.90.9-0.90.91.1-0.90.9-1.0-0.7-1.01.00.7
Time to tail flick, vehicle, after self-admin1.81.92.9-1.51.7-1.51.21.1-1.41.5-1.3-1.5-1.31.41.1
Time to tail flick, test, before self-admin0.50.50.7-0.70.7-0.70.60.8-0.70.6-0.6-0.7-0.80.80.3
Time to tail flick, test, after self-admin5.25.35.9-2.42.3-2.32.32.4-2.42.3-2.3-2.3-2.32.42.0
Delta time to tail flick, vehicle, before/after SA0.80.81.0-1.01.0-1.00.70.7-1.01.0-0.7-1.0-0.90.90.7
Delta time to tail flick, test, before/after SA1.21.11.6-1.00.9-1.01.10.9-1.11.1-1.1-1.1-0.90.91.3
Tibia length0.41.01.2-1.10.9-1.11.01.0-1.01.0-1.1-0.8-1.11.11.1
Ambulatory time before self-admin1.11.11.4-1.11.1-1.11.11.0-1.01.1-1.1-1.2-1.01.11.0
Ambulatory time after self-admin2.52.73.3-1.61.8-1.71.71.6-1.61.7-1.6-1.7-1.61.61.7
Bone: tissue strength1.21.21.4-1.11.1-1.21.10.9-1.21.2-1.1-1.0-1.01.11.2
Total heroin consumption2.32.72.9-1.61.7-1.71.61.6-1.71.6-1.7-1.6-1.61.61.5
Bone: trabecular number0.10.10.40.3-0.50.3-0.3-0.10.4-0.40.30.60.3-0.3-0.5
Bone: trabecular spacing0.00.00.10.1-0.30.1-0.2-0.20.1-0.20.20.10.0-0.10.0
Bone: trabecular thickness0.10.10.2-0.40.5-0.30.40.4-0.30.4-0.3-0.3-0.20.30.3
Bone: trabecular tissue density0.10.20.30.3-0.50.4-0.3-0.50.5-0.50.40.60.5-0.4-0.4
Water consumed over 24 hours1.51.82.1-1.31.3-1.31.31.4-1.51.5-1.3-1.2-1.31.21.4
Number of responses in last shaping day1.21.21.41.2-1.21.2-1.1-1.01.2-1.21.21.11.1-1.1-0.9