Hub : Genes

LOC108352133

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC108352133 0.13 0.07 8.5e-06 0.05 0.06 0.07 0.06 1.0e-03 3.7e-04 1.8e-04 5.3e-04
2 PL gene expression LOC108352133 0.05 0.03 3.5e-07 0.06 0.06 0.07 0.07 6.6e-07 4.1e-07 6.9e-08 8.1e-08
3 RMTg gene expression LOC108352133 0.22 0.1 9.0e-05 0.08 0.14 0.16 0.16 3.0e-03 1.8e-04 4.5e-05 3.4e-05
4 NAcc gene expression LOC108352133 0.2 0.08 3.3e-16 0.15 0.14 0.12 0.14 7.5e-17 2.2e-15 2.6e-14 1.1e-15
5 Brain gene expression LOC108352133 0.06 0.03 4.9e-06 0.05 0.06 0.06 0.06 1.0e-05 1.2e-06 1.1e-06 1.8e-06
6 pVTA gene expression LOC108352133 0.24 0.09 2.5e-12 0.26 0.24 0.24 0.22 2.0e-11 8.7e-11 1.0e-10 6.6e-10
7 LHb gene expression LOC108352133 0.58 0.16 1.0e-04 0.14 0.12 0.07 0.13 2.9e-04 7.0e-04 1.0e-02 6.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density1.32.13.41.91.7-1.51.71.01.01.1
Area under the delay curve0.70.71.60.30.70.11.00.91.11.2
BMI with tail1.24.06.9-2.3-1.71.4-2.1-2.6-2.1-1.6
BMI without tail0.10.20.7-0.40.00.3-0.4-0.8-0.7-0.4
Body weight2.610.713.2-3.2-3.53.6-3.3-3.2-3.1-3.0
Weight adjusted by age0.20.20.8-0.1-0.90.60.10.30.2-0.4
Bone surface0.10.10.50.20.10.3-0.1-0.5-0.4-0.7
Bone volume0.10.20.50.40.30.2-0.1-0.7-0.4-0.6
Breakpoint value in progressive ratio session0.40.41.50.30.7-1.20.30.40.20.7
Number of licking bursts0.30.30.80.20.3-0.5-0.9-0.4-0.7-0.4
Context. condit. distance diff. score0.20.30.7-0.5-0.10.00.50.90.50.7
Locomotion velocity, session 10.20.20.50.50.30.7-0.6-0.6-0.4-0.1
Locomotion distance, session 11.41.83.0-1.0-0.91.7-1.7-1.5-1.2-0.9
Locomotion velocity, session 20.10.10.40.50.4-0.1-0.00.60.30.4
Locomotion distance, session 20.20.20.60.1-0.30.7-0.8-0.3-0.5-0.2
Locomotion velocity, session 30.50.51.80.90.5-0.50.41.30.50.6
Locomotion distance, session 30.10.10.3-0.2-0.30.6-0.40.2-0.4-0.2
Stereotopy head waving bouts, day 32.93.45.32.31.7-1.92.01.71.71.6
Stereotopy head waving duration, day 30.40.51.01.00.4-0.61.00.50.70.3
Locomotion velocity, session 72.12.33.5-0.8-1.51.5-1.9-1.2-1.7-1.7
Locomotion distance, session 72.02.53.8-1.3-1.72.0-1.9-0.7-1.6-1.6
Stereotopy head waving bouts, day 71.21.32.01.11.3-1.41.10.71.11.2
Stereotopy head waving duration, day 71.61.92.51.31.5-1.61.40.81.51.4
Locomotion velocity, session 81.61.93.2-1.8-1.61.5-1.4-1.0-1.1-0.9
Locomotion distance, session 80.10.20.4-0.5-0.30.6-0.70.1-0.30.2
Degree of sensitization distance2.42.43.5-1.4-1.81.9-1.6-0.8-1.4-1.5
Degree of sensitization stereotypy1.21.32.01.01.4-1.31.00.71.21.3
Conditioned locomotion0.70.91.11.00.9-0.91.00.80.81.0
Cocaine response after cond. corrected0.80.92.31.51.2-0.30.60.60.81.1
Cocaine response after cond. not corrected0.60.72.71.60.80.20.60.80.50.7
Cocaine response before conditioning0.30.30.9-0.0-0.90.50.20.3-0.6-0.9
Saline control response0.20.20.6-0.4-0.60.8-0.4-0.4-0.3-0.3
Bone: connectivity density1.82.83.92.01.8-2.02.01.41.31.2
Bone: cortical apparent density3.34.46.52.22.1-2.52.01.82.21.7
Bone: cortical area0.10.20.50.70.30.6-0.10.4-0.2-0.2
Bone: cortical porosity0.10.20.4-0.00.5-0.40.4-0.6-0.40.1
Bone: cortical porosity0.10.10.30.10.4-0.20.5-0.5-0.30.1
Bone: cortical thickness1.52.54.82.21.5-0.81.42.11.21.4
Bone: cortical thickness8.39.612.03.53.0-2.03.23.43.23.1
Bone: cortical tissue density3.34.36.62.22.1-2.62.01.72.21.7
Condit. Reinf. active minus inactive responses2.02.33.61.31.6-1.21.41.61.51.9
Condit. Reinf. active-inactive response ratio2.42.63.91.41.6-1.41.52.01.51.8
Condit. Reinf. active responses1.62.03.11.21.6-1.21.21.61.21.8
Condit. Reinf. inactive responses0.10.10.20.30.5-0.30.10.30.10.4
Incentive salience index mean1.51.83.21.31.3-1.21.01.81.01.5
Condit. Reinf. lever presses0.20.20.90.4-0.0-0.6-0.21.0-0.30.0
Condit. Reinf. active minus inactive responses0.20.20.70.80.6-0.40.10.30.10.2
Condit. Reinf. active-inactive response ratio0.00.00.10.1-0.20.3-0.10.1-0.2-0.3
Condit. Reinf. active responses0.40.51.71.31.1-0.50.20.40.20.5
Condit. Reinf. inactive responses0.91.12.81.71.5-1.00.60.60.70.9
Condit. Reinf. lever presses0.20.20.40.50.6-0.30.20.70.40.6
Condit. Reinf. lever reinforcers received0.60.92.31.51.3-0.70.40.80.50.8
Conditioned reinforcement - actives0.00.00.10.10.10.3-0.20.3-0.1-0.2
Conditioned reinforcement - inactives0.10.10.80.20.0-0.20.1-0.10.2-0.9
Conditioned locomotion0.10.20.50.10.10.6-0.7-0.2-0.5-0.0
Patch foraging indifference point 0 sec0.50.94.21.20.20.30.52.10.2-0.1
Patch foraging indifference point AUC0.00.00.2-0.10.2-0.40.1-0.20.00.2
Delay disc. indifference point, 0s delay0.70.71.90.61.4-0.30.70.90.70.9
Delay disc. indifference point, 16s delay4.34.37.71.21.8-1.32.51.92.52.8
Delay disc. indifference point, 2s delay0.10.10.30.50.50.40.30.1-0.10.2
Delay disc. indifference point, 24s delay0.30.31.0-0.2-0.11.00.00.60.30.6
Delay disc. indifference point, 4s delay1.71.83.60.81.5-0.71.51.11.91.5
Delay disc. indifference point, 8s delay0.10.10.5-0.1-0.30.7-0.10.2-0.1-0.0
Indifference point function ln k0.10.20.50.3-0.00.30.50.70.5-0.0
Indifference point function log k0.10.20.50.3-0.00.30.50.70.5-0.0
Patch foraging total patch changes 0 sec0.40.63.00.9-0.10.50.21.7-0.1-0.4
Patch foraging total patch changes 12 sec1.41.85.02.21.4-1.00.81.50.51.1
Patch foraging total patch changes 18 sec0.10.10.20.30.2-0.1-0.10.4-0.5-0.1
Patch foraging total patch changes 24 sec1.01.32.01.41.2-1.01.01.30.81.1
Patch foraging total patch changes 6 sec0.50.83.11.00.3-0.00.91.80.60.5
Patch foraging time to switch 0 sec0.20.31.00.40.7-0.30.20.20.11.0
Patch foraging water rate 0 sec0.10.10.20.2-0.30.30.10.50.1-0.4
Patch foraging water rate 12 sec0.00.00.10.40.20.20.20.20.1-0.1
Patch foraging water rate 18 sec0.30.51.51.20.5-0.50.30.80.6-0.0
Patch foraging water rate 24 sec0.00.10.20.3-0.1-0.20.00.30.1-0.5
Patch foraging water rate 6 sec1.11.62.91.71.3-1.21.21.21.01.1
Seeking ratio, delayed vs. immediate footshock1.21.42.10.61.0-1.31.31.41.51.1
Distance traveled before self-admin0.10.10.3-0.4-0.40.60.10.10.2-0.5
Distance traveled after self-admin0.60.61.4-1.2-0.90.4-0.5-1.0-0.3-0.8
Extensor digitorum longus weight5.521.632.4-5.7-4.95.0-4.4-4.1-4.1-4.1
Bone: elastic displacement0.30.40.6-0.3-0.60.7-0.7-0.3-0.7-0.8
Bone: elastic work0.30.30.91.00.9-0.30.50.40.20.4
Bone: endosteal estimation3.06.68.6-2.5-2.12.8-2.4-2.9-2.4-2.7
Bone: endosteal perimeter2.24.55.5-2.2-1.72.0-2.2-2.4-2.1-2.2
Epididymis fat weight0.41.02.3-0.3-1.40.9-0.8-0.3-1.1-1.5
Delta time in closed arm before/after self-admin0.80.81.5-1.2-0.70.5-0.9-1.1-0.8-1.0
Delta time in open arm before/after self-admin0.20.20.4-0.6-0.2-0.20.5-0.60.4-0.2
Diff in mean of infusions in LGA sessions0.10.10.20.50.3-0.30.20.3-0.30.0
Delay discount exponential model param0.70.71.5-0.2-0.6-0.1-1.0-0.9-1.1-1.2
Extinction: sum of active levers before priming1.81.72.3-1.4-1.21.2-1.2-1.3-1.4-1.5
Active lever presses in extinction session 61.51.42.41.41.3-1.51.10.61.11.0
Bone: final force0.30.42.11.50.60.30.30.4-0.2-0.1
Bone: final moment0.20.31.71.30.40.60.10.2-0.4-0.3
Food consumed during 24 hour testing period0.60.81.7-1.3-0.90.5-1.1-0.8-0.8-0.6
Glucose0.10.20.60.10.3-0.60.3-0.8-0.1-0.2
Heart weight2.43.44.2-2.1-1.91.9-1.9-1.4-1.8-1.9
Delay discount hyperbolic model param0.60.71.3-0.3-0.6-0.2-1.0-0.9-1.1-1.1
Intermittent access intake day 1-15 change1.41.42.91.21.6-1.71.2-0.51.10.5
Intermittent access intake escalation2.02.04.01.32.0-2.01.4-0.31.30.8
Intermittent access intake escalation 20.60.61.40.61.2-1.20.4-0.80.30.4
Intermitt. access day 1 inactive lever presses3.63.95.51.91.4-2.22.41.62.31.9
Intermitt. access day 15 inactive lever presses2.72.94.11.92.0-1.41.91.21.71.6
Intermitt. access escalation Index0.10.10.2-0.5-0.10.2-0.1-0.2-0.20.1
Intermittent access day 1 total infusions0.10.10.20.10.10.50.10.50.4-0.1
Intermittent access day 15 total infusions1.82.03.71.31.9-1.51.60.61.71.0
Intermittent access terminal intake (last 3 days)1.11.22.11.11.4-1.11.20.51.40.7
Intermittent access total infusions0.60.61.10.71.1-0.50.90.61.00.5
Intermittent access day 1 locomotion0.30.40.6-0.3-0.70.8-0.7-0.4-0.3-0.8
Intermittent access day 15 total locomotion0.70.82.1-0.3-0.50.7-1.0-1.4-0.6-1.0
Intermittent access total locomotion0.10.10.30.50.3-0.1-0.2-0.30.2-0.2
Intermittent access standard deviation2.42.63.71.81.9-1.91.60.81.51.4
Left kidney weight0.41.03.20.80.6-0.40.61.30.91.8
Right kidney weight0.41.21.81.40.8-0.71.00.91.31.3
Cocaine induced anxiety0.10.10.2-0.30.20.3-0.2-0.0-0.30.4
Post-drug Anxiety0.20.20.40.00.5-0.20.60.70.50.6
Baseline Anxiety0.10.10.20.4-0.00.10.30.50.5-0.2
Tail length0.10.21.3-0.0-0.21.1-0.10.50.20.1
Length with tail0.72.57.3-1.5-2.02.7-1.3-0.5-0.8-1.3
Length without tail1.12.54.8-1.5-2.22.1-1.3-1.0-1.0-1.5
Times rat made contact with spout0.10.10.40.0-0.10.1-0.3-0.5-0.5-0.6
Lifetime Intake0.91.01.80.71.2-0.51.30.91.40.6
Liver weight, left0.00.00.20.10.1-0.30.10.20.20.4
Liver weight, right2.64.35.82.22.0-1.82.41.52.22.1
Locomotor activity0.30.51.51.20.9-0.8-0.30.30.30.4
Locomotor testing distance1.01.73.51.91.6-1.50.61.11.11.0
Locomotor testing rearing3.96.07.42.72.6-2.62.42.52.41.9
Locomotion in novel chamber4.35.36.22.52.5-1.92.42.42.42.0
Locomotion in novel chamber post-restriction0.10.10.30.30.2-0.1-0.5-0.4-0.1-0.5
Fecal boli incidents, locomotor time 11.71.93.6-1.2-1.40.8-1.4-1.9-1.2-1.5
Change in fecal boli incidents, locomotor task0.50.41.00.60.7-0.50.20.90.41.0
Time >=10cm from walls, locomotor time 10.40.40.90.40.5-0.90.40.90.40.6
Bouts of movement, locomotor time 10.10.10.3-0.5-0.30.3-0.3-0.4-0.1-0.1
Total resting periods, locomotor time 10.91.01.3-1.2-1.01.0-1.0-1.1-0.8-0.8
Rest time, locomotor task time 11.61.83.1-1.4-1.30.7-1.2-1.8-1.1-1.6
Distance moved, locomotor task time 11.92.03.31.11.8-0.71.31.61.51.7
Vertical activity count, locomotor time 10.10.10.30.10.3-0.00.20.20.20.6
Time >=10cm from walls, locomotor time 20.70.71.71.20.8-1.30.41.00.20.4
Bouts of movement, locomotor time 21.11.13.01.20.3-0.81.11.70.51.2
Total resting periods, locomotor time 21.01.12.91.00.1-0.71.21.70.51.1
Rest time, locomotor task time 21.41.62.9-1.5-1.70.6-0.9-1.4-1.1-1.4
Distance moved, locomotor task time 20.30.41.20.41.10.40.30.50.70.6
Vertical activity count, locomotor time 20.20.20.8-0.30.30.9-0.1-0.30.1-0.2
Light reinforcement 11.63.06.42.51.8-1.41.31.91.51.4
Light reinforcement 20.40.61.10.90.9-0.10.60.60.61.1
Bone: marrow area2.96.28.1-2.5-2.12.7-2.4-2.8-2.3-2.6
Bone: maximum diameter0.10.10.40.20.20.6-0.3-0.2-0.2-0.3
Bone: maximum force0.20.40.90.4-0.21.0-0.4-0.4-1.0-0.8
Bone: maximum moment0.30.61.40.3-0.41.2-0.5-0.5-1.1-0.9
Mean time between licks in bursts3.24.58.0-1.8-1.70.6-2.8-2.0-2.5-2.6
Mean num. licks in bursts0.20.20.7-0.1-0.20.50.80.20.60.1
Cd content in liver0.20.20.6-0.4-0.4-0.70.80.00.20.0
Co content in liver0.20.31.0-1.0-0.70.5-0.0-0.2-0.2-0.1
Cu content in liver0.40.51.00.00.4-0.41.00.90.71.0
Fe content in liver0.10.10.4-0.6-0.30.6-0.4-0.1-0.00.1
K content in liver4.14.15.52.12.3-2.12.11.32.02.0
Mg content in liver5.55.66.72.02.6-2.42.61.92.52.5
Mn content in liver5.56.39.42.73.0-3.12.01.92.22.4
Na content in liver0.50.51.20.20.9-0.90.9-1.10.5-0.0
Rb content in liver0.91.11.71.00.9-1.30.91.30.80.9
Se content in liver7.59.210.33.23.2-3.03.12.53.03.1
Sr content in liver0.20.20.90.50.20.10.20.90.20.1
Zn content in liver1.11.22.00.90.9-1.31.11.11.40.9
Bone: minimum diameter0.40.81.1-0.6-0.61.1-0.9-1.0-0.9-1.1
Time in familiar zone, hab. session 10.30.30.70.60.8-0.80.1-0.30.10.4
Time in novel zone, hab. session 10.20.20.50.40.2-0.10.50.70.40.1
Total zone transitions, hab. session 10.60.82.1-1.5-1.31.2-0.6-0.3-0.4-0.3
Total locomotion distance, hab. session 10.30.40.80.10.3-0.40.60.80.70.9
Locomotion velocity, hab. session 10.10.20.6-0.2-0.0-0.20.40.60.60.7
Time in familiar zone, hab. session 22.72.84.51.42.1-2.11.30.61.62.0
Time in novel zone, hab. session 20.70.71.70.1-1.01.1-0.40.2-0.8-1.3
Total zone transitions, hab. session 21.21.62.4-1.3-1.41.5-1.3-1.0-1.2-1.0
Total locomotion distance, hab. session 20.60.81.0-0.9-1.00.8-0.8-1.0-0.9-0.7
Locomotion velocity, hab. session 20.70.91.2-1.1-1.10.8-0.9-1.0-1.0-0.8
Novel to familiar place preference ratio0.20.20.5-0.20.10.10.50.40.70.7
Novelty place preference0.20.20.5-0.10.10.10.50.60.70.7
Time in novel zone, NPP test0.50.51.00.40.4-0.20.80.91.00.9
Total zone transitions, NPP test1.72.53.8-1.4-1.51.9-1.8-1.4-1.6-1.3
Total locomotion distance, NPP test0.60.91.4-0.7-0.91.2-1.1-0.7-1.0-0.8
Locomotion velocity, NPP test1.21.72.5-1.4-1.31.6-1.4-1.0-1.3-1.0
Intraocular pressure3.34.69.5-3.1-2.42.5-1.7-1.8-1.8-1.4
Delta distance traveled before/after self-admin0.20.20.9-0.5-0.2-0.5-0.5-1.0-0.3-0.1
Delta ambulatory time before/after self-admin0.40.41.8-0.5-0.1-0.2-0.7-1.3-0.4-0.2
Parametrial fat weight0.61.13.41.80.9-0.71.21.00.90.4
Pavlov. Cond. lever latency0.40.51.4-1.0-0.40.8-0.3-1.2-0.3-0.4
Pavlov. Cond. magazine entry latency4.45.79.03.02.6-2.72.22.12.01.9
Pavlov. Cond. change in total contacts5.45.79.52.31.9-2.32.63.12.32.1
Pavlov. Cond. index score1.82.24.02.01.4-1.71.31.71.21.0
Pavlov. Cond. latency score1.11.42.71.61.0-1.41.01.40.90.6
Pavlov. Cond. lever contacts0.10.10.50.4-0.2-0.5-0.10.7-0.1-0.2
Pavlov. Cond. magazine entry number5.16.49.0-3.0-2.62.8-2.4-2.5-2.2-2.1
Pavlov. Cond. intertrial magazine entries0.30.41.3-1.1-0.50.3-0.6-0.8-0.6-0.2
Pavlov. Cond. lever-magazine prob. diff.2.22.85.02.21.5-1.91.42.01.31.1
Pavlov. Cond. response bias3.84.76.82.52.0-2.22.02.61.81.7
Pavlov. Cond. lever latency0.10.10.3-0.5-0.60.30.1-0.3-0.1-0.1
Pavlov. Cond. magazine entry latency0.20.20.5-0.3-0.40.7-0.4-0.4-0.2-0.7
Pavlov. Cond. change in total contacts0.10.10.30.50.6-0.30.10.30.0-0.2
Pavlov. Cond. index score0.10.10.20.20.30.3-0.4-0.2-0.1-0.3
Pavlov. Cond. latency score0.10.10.40.00.10.4-0.6-0.4-0.3-0.5
Pavlov. Cond. lever contacts0.20.20.60.80.8-0.4-0.10.40.10.2
Pavlov. Cond. magazine entry number0.10.10.2-0.5-0.5-0.20.00.0-0.20.2
Pavlov. Cond. intertrial magazine entries0.60.82.3-1.4-1.50.9-0.30.4-0.4-0.5
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.10.20.4-0.5-0.2-0.2-0.4
Pavlov. Cond. response bias0.40.51.31.11.0-0.50.30.70.60.4
Time in closed arm before self-admin1.21.32.91.31.5-1.10.50.80.61.7
Time in closed arm after self-admin0.90.92.40.51.3-1.20.10.50.21.5
Time in open arm before self-admin0.50.51.2-0.3-1.00.8-0.6-0.1-0.5-1.1
Time in open arm after self-admin1.11.22.9-1.0-1.31.0-0.5-0.8-0.7-1.7
Bone: periosteal estimation0.71.42.9-0.6-0.71.7-1.1-1.2-1.2-1.3
Bone: periosteal perimeter1.11.82.8-0.9-0.91.5-1.7-1.5-1.5-1.4
Bone: post-yield work1.41.92.5-1.4-1.61.5-1.2-0.8-1.5-1.3
Progressive ratio test 1 active lever presses0.40.51.10.60.7-0.40.90.61.00.1
Progressive ratio test 1 breakpoint0.50.51.20.70.7-0.40.90.51.10.2
Progressive ratio test 1 inactive lever presses1.71.93.01.31.2-1.21.71.41.70.6
Progressive ratio test 2 active lever presses0.20.20.40.60.6-0.10.50.30.6-0.1
Progressive ratio test 2 breakpoint0.10.20.30.50.40.00.50.10.6-0.2
Progressive ratio test 2 inactive lever presses0.20.20.40.50.7-0.00.40.20.6-0.0
Incentive Sensitization - Responses0.60.61.2-0.1-0.71.0-0.7-0.5-0.8-1.1
Incentive Sensitization - Breakpoint0.50.50.9-0.0-0.60.9-0.6-0.6-0.6-1.0
Sum of active levers in priming session hrs 5-61.51.43.20.71.2-1.81.30.61.21.1
Progressive ratio0.10.10.20.20.3-0.40.1-0.30.20.1
Food seeking constrained by brief footshock0.20.20.60.50.5-0.20.30.00.60.7
Seeking ratio, punishment vs. effort0.00.00.2-0.00.10.4-0.10.10.10.2
Retroperitoneal fat weight0.00.20.60.8-0.30.4-0.10.3-0.1-0.4
Reaction time number correct0.91.41.8-1.3-1.20.7-1.3-1.0-1.2-1.3
Reaction time mean minus median1.72.33.5-1.7-1.61.2-1.3-1.4-1.3-1.9
Reaction time mean minus median AUC0.91.22.3-1.5-1.00.8-0.9-1.0-0.9-1.3
Reaction time num false alarms0.20.30.60.30.7-0.5-0.5-0.7-0.5-0.2
Reaction time num false alarms AUC0.30.40.90.20.4-0.2-1.0-0.9-0.9-0.5
Reaction time trials correct on left0.91.41.8-1.3-1.20.7-1.3-1.0-1.2-1.3
Reaction time trials on left1.01.41.8-1.3-1.20.7-1.3-1.0-1.2-1.4
Reaction time mean0.40.60.90.40.8-0.91.00.51.00.6
Reaction time mean AUC0.50.71.20.30.9-0.91.10.61.10.7
Median of all reaction times1.62.22.81.31.6-1.61.61.21.71.3
Reaction time omissions0.30.40.70.80.8-0.80.50.40.50.5
Reaction time false alarm rate0.20.31.00.81.0-0.5-0.2-0.3-0.20.2
Reaction time premature initiation rate3.54.76.62.22.3-1.72.21.72.42.6
Reaction time premature initiations1.01.41.91.01.3-1.01.20.81.41.4
Std. dev. reaction times0.40.51.0-0.9-0.60.3-0.5-0.9-0.6-1.0
Reaction time trials completed1.01.41.8-1.3-1.20.7-1.3-1.0-1.2-1.4
Reaction time trials AUC1.01.41.9-1.3-1.20.6-1.4-1.0-1.2-1.4
Run reversals in cocaine runway, females0.70.62.4-0.10.10.50.71.60.51.0
Run reversals in cocaine runway, males0.50.41.20.50.20.00.80.81.10.5
Latency to leave start box in cocaine runway0.10.10.7-0.2-0.10.1-0.8-0.1-0.50.2
Latency to leave start box in cocaine runway, F0.10.10.2-0.5-0.3-0.1-0.3-0.1-0.00.1
Latency to leave start box in cocaine runway, M0.70.71.51.20.9-0.40.01.20.11.0
Std. dev. time between licks in bursts0.50.61.8-0.2-0.1-0.3-1.4-0.6-1.1-0.8
Total sessions with >9 infusions1.21.32.20.81.2-0.81.51.11.51.1
Short access day 1 total inactive lever presses0.91.02.30.80.5-0.71.51.01.50.1
Short access day 10 total inactive lever presses0.10.10.30.1-0.2-0.10.50.50.60.3
Short access day 1 total infusions2.52.64.81.21.4-1.02.21.82.21.1
Short access day 10 total infusions0.20.20.60.20.40.10.60.20.8-0.0
Short access total infusions1.82.13.71.01.4-0.81.91.51.91.0
Short access day 1 locomotion2.22.33.51.71.2-1.31.61.91.71.3
Short access day 10 total locomotion0.40.40.80.2-0.70.2-0.5-0.9-0.5-0.9
Short access total locomotion0.00.00.20.2-0.50.10.00.10.1-0.2
One hour access (0.3 mA shock)0.00.10.2-0.10.30.20.2-0.10.1-0.4
Compulsive drug intake1.01.01.7-1.1-1.30.9-0.70.1-1.0-1.2
One hour access (shock baseline)0.50.61.10.81.0-0.50.90.31.00.5
Social response proportion0.00.00.1-0.1-0.00.30.10.3-0.00.0
Social responses0.00.10.10.30.40.2-0.30.30.00.0
Social time1.62.23.5-0.9-1.31.8-1.5-1.2-1.5-1.9
Soleus weight0.41.22.8-0.4-0.50.9-1.2-1.7-1.0-1.3
Bone: stiffness0.10.10.20.50.10.30.50.1-0.1-0.1
Tibialis anterior weight0.93.05.9-2.4-1.81.7-1.2-2.0-1.0-1.4
Time to tail flick, vehicle, before self-admin1.71.72.4-1.2-1.61.3-1.5-0.7-1.6-1.2
Time to tail flick, vehicle, after self-admin1.31.42.9-1.1-1.71.4-0.7-0.5-1.0-1.3
Time to tail flick, test, before self-admin1.21.22.3-1.2-0.81.5-1.1-1.0-0.8-0.9
Time to tail flick, test, after self-admin1.01.02.2-0.8-1.01.0-1.5-0.6-1.1-0.9
Delta time to tail flick, vehicle, before/after SA0.30.30.6-0.4-0.60.6-0.1-0.8-0.3-0.8
Delta time to tail flick, test, before/after SA0.10.10.50.4-0.1-0.1-0.10.70.10.1
Tibia length0.92.53.4-1.5-1.81.5-1.7-1.7-1.5-1.3
Ambulatory time before self-admin0.40.40.8-0.6-0.90.8-0.10.3-0.0-0.9
Ambulatory time after self-admin1.21.42.1-1.3-1.31.0-0.8-1.5-0.6-1.4
Bone: tissue strength2.62.54.9-1.3-1.60.8-1.9-1.0-2.2-1.8
Total heroin consumption0.20.31.10.70.4-1.10.10.20.20.4
Bone: trabecular number2.64.15.92.42.3-2.42.31.21.51.6
Bone: trabecular spacing1.82.33.7-1.7-1.51.9-1.6-1.5-0.9-1.1
Bone: trabecular thickness0.10.10.30.50.40.1-0.1-0.3-0.5-0.4
Bone: trabecular tissue density0.30.41.80.2-0.30.30.51.30.40.3
Water consumed over 24 hours0.40.41.1-0.4-0.40.2-1.0-0.6-1.0-0.6
Number of responses in last shaping day1.31.31.91.31.4-1.31.20.61.21.0