Hub : Genes

LOC108349032

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative TSS XR_010060960.1 0.04 0.02 1.0e-04 0.03 0.03 0.02 0.02 5.9e-04 2.8e-04 1.2e-03 1.2e-03
2 Adipose isoform ratio XR_010060959.1 0.02 0.02 4.6e-03 0.01 0.01 0 0 7.1e-02 1.1e-02 1.0e-01 9.1e-02
3 PL alternative TSS XR_010060960.1 0.03 0.02 3.1e-03 0.02 0.01 0.01 0.01 1.9e-03 2.8e-02 5.9e-02 3.6e-02
4 PL alternative TSS XR_010060958.1 0.03 0.02 2.3e-03 0.03 0.01 0.01 0.01 6.4e-04 2.3e-02 5.1e-02 1.4e-02
5 Adipose gene expression LOC108349032 0.03 0.02 8.3e-03 0 0.02 0.01 0.01 1.0e-01 4.4e-03 9.7e-03 2.7e-02
6 Liver alternative TSS XR_010060958.1 0.03 0.02 2.7e-04 0.03 0.03 0.03 0.03 2.6e-04 3.0e-04 4.5e-04 5.5e-04
7 Liver alternative TSS XR_010060958.1 0.03 0.02 4.5e-04 0.05 0.04 0.04 0.04 4.5e-06 5.3e-05 3.3e-05 1.6e-05
8 Liver alternative TSS XR_010060960.1 0.03 0.02 2.2e-03 0.03 0.03 0.02 0.02 1.2e-04 5.0e-04 1.7e-03 1.5e-03
9 pVTA alternative TSS XR_010060958.1 0.04 0.03 6.1e-03 0.01 0.01 0.01 0 2.4e-02 7.1e-02 1.1e-01 2.8e-01
10 pVTA alternative TSS XR_010060960.1 0.04 0.03 5.3e-03 0.03 0.01 0 0 3.8e-03 8.4e-02 1.6e-01 3.1e-01
11 Liver isoform ratio XR_010060959.1 0.04 0.02 1.1e-03 0.01 0.01 0.02 0.01 8.0e-03 6.8e-03 3.6e-03 4.3e-02
12 BLA alternative TSS XR_010060958.1 0.07 0.04 4.4e-03 0.04 0.04 0.04 0.04 5.4e-03 2.8e-03 5.5e-03 4.8e-03
13 PL gene expression LOC108349032 0.06 0.03 2.7e-04 0.01 0.03 0.02 0.02 1.5e-02 2.3e-04 1.3e-03 1.8e-03
14 Liver gene expression LOC108349032 0.21 0.1 1.7e-03 0.04 0 0.04 0.04 1.6e-05 1.2e-01 1.7e-05 2.9e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.81.55.5-0.6-1.90.7-0.7-2.3-0.7-0.70.7-1.81.8-0.51.20.70.6
Area under the delay curve0.20.31.40.10.60.1-0.11.10.1-0.10.10.2-0.2-0.00.1-0.8-1.2
BMI with tail1.44.79.12.10.9-2.22.2-1.92.22.2-2.22.0-2.02.9-2.53.01.4
BMI without tail1.57.910.83.33.2-3.23.20.33.13.2-3.23.2-3.22.9-2.71.40.7
Body weight2.511.019.32.93.2-3.33.30.63.43.2-3.24.4-4.43.9-4.42.70.4
Weight adjusted by age1.33.88.51.42.3-1.61.61.01.71.8-1.82.9-2.92.0-2.31.1-1.4
Bone surface0.10.22.3-0.3-0.30.1-0.10.1-0.2-0.20.2-0.00.0-0.0-0.30.21.5
Bone volume0.10.21.20.1-0.4-0.10.1-0.90.20.0-0.0-0.30.30.3-0.10.71.1
Breakpoint value in progressive ratio session0.20.40.6-0.6-0.40.5-0.50.4-0.5-0.70.7-0.80.8-0.80.6-0.70.6
Number of licking bursts0.51.42.3-1.5-0.81.4-1.41.4-1.3-1.51.5-0.50.5-1.30.5-1.01.1
Context. condit. distance diff. score4.65.610.7-3.3-2.73.0-3.0-0.1-2.9-3.03.0-1.91.9-2.41.6-0.50.3
Locomotion velocity, session 10.80.91.9-0.9-0.11.0-1.01.0-1.0-0.90.9-0.40.4-1.21.1-1.4-0.9
Locomotion distance, session 10.81.02.1-0.8-1.51.0-1.0-1.3-1.0-0.90.9-1.31.3-0.91.20.00.4
Locomotion velocity, session 20.81.01.8-1.1-0.71.3-1.30.5-1.3-1.01.0-0.70.7-1.10.9-0.90.5
Locomotion distance, session 21.52.14.3-1.6-2.11.7-1.7-1.3-1.7-1.51.5-1.51.5-1.11.10.3-0.2
Locomotion velocity, session 30.20.20.70.80.7-0.50.50.10.50.4-0.40.2-0.2-0.00.3-0.50.4
Locomotion distance, session 31.61.82.9-1.1-1.51.4-1.4-0.8-1.4-1.51.5-1.61.6-1.61.7-0.60.1
Stereotopy head waving bouts, day 30.50.63.20.01.0-0.30.31.80.30.2-0.21.3-1.30.1-0.9-0.40.2
Stereotopy head waving duration, day 31.21.53.80.81.8-1.01.02.01.01.0-1.01.7-1.70.4-1.0-0.6-0.4
Locomotion velocity, session 74.95.410.8-2.4-3.32.4-2.4-2.3-2.4-2.52.5-2.72.7-2.02.00.3-0.9
Locomotion distance, session 75.06.411.3-2.4-3.12.5-2.5-1.8-2.4-2.72.7-3.43.4-2.62.8-0.7-1.0
Stereotopy head waving bouts, day 70.70.93.90.61.4-0.50.52.00.50.3-0.30.7-0.7-0.40.4-1.9-0.1
Stereotopy head waving duration, day 70.70.92.50.81.5-0.70.71.60.80.7-0.71.1-1.10.1-0.1-1.20.1
Locomotion velocity, session 82.63.15.9-2.4-0.92.3-2.32.1-2.2-2.22.2-0.40.4-2.20.7-1.50.3
Locomotion distance, session 85.68.114.3-3.7-3.83.5-3.5-1.2-3.5-3.53.5-2.52.5-2.61.70.20.4
Degree of sensitization distance0.40.41.1-1.0-0.60.8-0.80.5-0.8-0.90.9-0.50.5-0.50.1-0.20.1
Degree of sensitization stereotypy0.40.53.20.20.70.1-0.11.3-0.0-0.10.1-0.00.0-0.81.0-1.80.2
Conditioned locomotion0.30.41.60.00.1-0.30.30.00.40.2-0.20.8-0.80.8-1.21.10.5
Cocaine response after cond. corrected1.01.44.1-1.3-2.01.1-1.1-1.4-1.0-1.01.0-1.21.2-0.3-0.11.31.4
Cocaine response after cond. not corrected0.20.41.8-0.8-0.50.6-0.60.5-0.6-0.60.60.0-0.0-0.1-0.60.41.3
Cocaine response before conditioning3.23.911.11.63.3-1.41.43.31.41.4-1.42.8-2.80.9-1.4-1.4-0.3
Saline control response4.76.511.23.33.0-3.23.20.23.23.3-3.32.0-2.02.6-1.60.4-0.2
Bone: connectivity density0.81.34.8-0.8-2.00.8-0.8-2.2-0.8-0.60.6-1.31.3-0.20.61.10.7
Bone: cortical apparent density1.01.62.51.60.5-1.51.5-1.31.61.4-1.40.6-0.61.6-1.01.40.8
Bone: cortical area0.10.21.30.10.3-0.00.00.70.0-0.20.20.6-0.60.0-0.4-0.11.1
Bone: cortical porosity1.41.57.20.71.9-0.30.32.50.30.2-0.20.4-0.4-0.70.9-2.7-1.5
Bone: cortical porosity1.51.67.20.31.7-0.00.02.7-0.0-0.00.00.5-0.5-0.70.8-2.6-1.9
Bone: cortical thickness0.40.71.71.30.4-0.90.9-0.91.00.8-0.80.4-0.40.7-0.30.51.2
Bone: cortical thickness1.01.22.81.70.6-1.31.3-1.21.31.3-1.30.5-0.51.2-0.60.90.8
Bone: cortical tissue density1.01.52.51.50.6-1.51.5-1.21.61.4-1.40.6-0.61.5-1.01.30.7
Condit. Reinf. active minus inactive responses0.70.82.2-0.4-0.10.8-0.80.6-0.8-0.80.8-0.60.6-1.11.4-1.5-1.0
Condit. Reinf. active-inactive response ratio0.20.30.70.80.9-0.40.40.40.40.4-0.40.5-0.50.10.2-0.7-0.4
Condit. Reinf. active responses0.60.81.9-0.6-0.70.9-0.9-0.5-0.9-0.80.8-1.11.1-1.01.4-0.7-0.7
Condit. Reinf. inactive responses1.41.84.6-0.8-1.80.9-0.9-2.0-1.0-0.90.9-2.22.2-0.91.50.30.1
Incentive salience index mean2.43.14.9-2.0-1.62.2-2.20.3-2.2-2.12.1-1.51.5-1.91.7-1.1-0.6
Condit. Reinf. lever presses3.95.910.5-3.2-3.13.0-3.0-0.6-3.0-2.92.9-2.32.3-2.21.4-0.00.3
Condit. Reinf. active minus inactive responses0.71.13.31.01.8-0.90.91.50.80.8-0.81.4-1.40.5-0.7-0.5-0.4
Condit. Reinf. active-inactive response ratio0.71.13.70.61.8-0.70.71.90.60.7-0.71.6-1.60.4-0.9-0.6-0.3
Condit. Reinf. active responses0.30.41.30.71.1-0.60.60.70.60.5-0.50.7-0.70.3-0.3-0.4-0.2
Condit. Reinf. inactive responses0.10.10.40.60.1-0.40.4-0.60.50.3-0.3-0.10.10.40.10.20.2
Condit. Reinf. lever presses0.10.20.90.10.50.1-0.10.5-0.1-0.10.1-0.10.1-0.40.8-1.0-0.4
Condit. Reinf. lever reinforcers received0.20.31.20.51.1-0.40.41.00.30.3-0.30.6-0.6-0.00.0-0.8-0.1
Conditioned reinforcement - actives0.00.20.30.50.3-0.40.4-0.60.20.6-0.6-0.00.00.3-0.10.4-0.4
Conditioned reinforcement - inactives0.20.51.60.70.8-0.80.8-0.20.70.9-0.90.4-0.40.7-0.20.2-1.3
Conditioned locomotion0.10.11.30.10.3-0.20.2-0.10.00.2-0.20.1-0.10.4-0.10.2-1.2
Patch foraging indifference point 0 sec1.33.86.42.52.2-2.52.5-0.12.32.5-2.51.3-1.32.2-1.30.6-0.8
Patch foraging indifference point AUC0.20.42.10.30.8-0.10.11.50.10.2-0.20.0-0.0-0.20.3-1.30.5
Delay disc. indifference point, 0s delay0.30.30.8-0.9-0.50.7-0.70.4-0.7-0.80.8-0.20.2-0.50.1-0.2-0.8
Delay disc. indifference point, 16s delay0.20.20.90.70.6-0.50.50.00.50.3-0.30.1-0.10.50.2-0.4-0.9
Delay disc. indifference point, 2s delay0.60.73.9-0.11.20.2-0.22.0-0.00.0-0.00.8-0.8-0.2-0.3-1.1-1.4
Delay disc. indifference point, 24s delay0.50.82.70.91.5-0.70.71.30.80.5-0.50.8-0.80.5-0.1-1.0-1.7
Delay disc. indifference point, 4s delay0.60.72.50.71.4-0.50.51.60.70.5-0.50.9-0.90.4-0.7-0.7-0.3
Delay disc. indifference point, 8s delay0.20.31.6-0.3-0.00.4-0.40.5-0.3-0.40.4-0.30.3-0.30.4-0.7-1.3
Indifference point function ln k0.30.81.5-1.0-0.40.9-0.91.0-0.9-1.21.2-0.40.4-1.10.6-1.0-0.1
Indifference point function log k0.30.81.5-1.0-0.40.9-0.91.0-0.9-1.21.2-0.40.4-1.10.6-1.0-0.1
Patch foraging total patch changes 0 sec1.33.96.92.62.2-2.62.6-0.22.42.6-2.61.2-1.22.3-1.30.6-0.9
Patch foraging total patch changes 12 sec1.62.24.32.01.7-1.91.90.21.72.1-2.10.9-0.91.4-0.80.10.5
Patch foraging total patch changes 18 sec1.02.44.32.10.6-1.91.9-1.91.72.1-2.10.1-0.11.9-0.71.40.8
Patch foraging total patch changes 24 sec0.30.93.31.1-0.1-1.01.0-1.81.00.9-0.9-0.70.70.90.40.6-0.7
Patch foraging total patch changes 6 sec1.83.15.42.31.8-2.22.2-0.42.12.3-2.31.1-1.12.1-1.00.6-1.0
Patch foraging time to switch 0 sec0.41.57.30.5-0.8-0.70.7-2.60.60.5-0.50.5-0.51.4-1.22.70.6
Patch foraging water rate 0 sec0.10.31.30.40.7-0.60.60.50.60.5-0.50.4-0.40.6-0.5-0.0-1.2
Patch foraging water rate 12 sec0.00.20.60.3-0.4-0.20.2-0.80.4-0.00.0-0.70.7-0.10.50.00.1
Patch foraging water rate 18 sec0.20.41.30.70.6-0.90.9-0.11.10.5-0.50.4-0.40.5-0.40.2-1.1
Patch foraging water rate 24 sec0.20.20.90.60.3-0.70.7-0.31.00.4-0.4-0.10.10.4-0.20.20.3
Patch foraging water rate 6 sec0.00.10.20.3-0.1-0.30.3-0.40.30.1-0.1-0.30.30.10.00.10.0
Seeking ratio, delayed vs. immediate footshock0.81.25.11.21.4-0.90.91.60.90.7-0.70.3-0.30.1-0.3-1.12.3
Distance traveled before self-admin0.20.42.1-0.3-0.60.2-0.2-0.5-0.4-0.10.10.1-0.10.3-0.91.21.4
Distance traveled after self-admin0.81.32.91.01.3-0.90.91.10.81.0-1.01.6-1.60.8-1.40.21.7
Extensor digitorum longus weight0.00.20.8-0.50.00.2-0.20.5-0.2-0.40.40.3-0.30.2-0.60.4-0.9
Bone: elastic displacement0.30.42.70.70.6-0.50.5-0.10.40.6-0.6-0.30.30.10.6-0.6-1.6
Bone: elastic work0.20.30.80.60.7-0.50.50.20.50.6-0.60.4-0.40.5-0.3-0.1-0.9
Bone: endosteal estimation1.23.011.00.22.3-0.90.93.30.80.7-0.72.8-2.80.9-2.4-0.10.1
Bone: endosteal perimeter0.51.15.5-1.30.30.9-0.92.4-0.9-1.01.01.0-1.0-0.5-1.0-0.40.7
Epididymis fat weight2.713.828.14.51.1-4.34.3-5.34.44.2-4.21.4-1.44.6-2.44.60.5
Delta time in closed arm before/after self-admin0.50.51.20.30.4-0.50.5-0.20.50.5-0.50.9-0.90.9-1.11.0-0.3
Delta time in open arm before/after self-admin0.20.20.50.70.6-0.50.5-0.30.40.7-0.70.0-0.00.20.1-0.0-0.3
Diff in mean of infusions in LGA sessions1.93.47.5-2.0-2.72.0-2.0-1.3-1.9-1.81.8-2.42.4-1.51.40.00.6
Delay discount exponential model param0.30.41.6-0.2-0.8-0.00.0-1.3-0.20.1-0.1-0.30.30.0-0.01.01.2
Extinction: sum of active levers before priming0.50.71.3-1.1-0.71.1-1.10.5-1.1-1.11.1-0.50.5-0.80.3-0.4-0.1
Active lever presses in extinction session 60.30.33.00.40.2-0.40.4-0.70.40.4-0.4-0.20.20.40.20.3-1.7
Bone: final force1.52.44.21.61.0-1.61.6-0.61.71.6-1.61.6-1.62.1-1.91.70.9
Bone: final moment1.32.23.81.51.1-1.61.6-0.51.71.5-1.51.5-1.51.9-1.71.50.5
Food consumed during 24 hour testing period0.20.31.6-0.4-0.30.0-0.0-0.10.10.1-0.10.6-0.60.5-1.31.30.3
Glucose2.03.26.7-2.6-0.62.1-2.12.5-2.1-2.22.2-0.10.1-2.00.4-1.4-1.6
Heart weight2.03.27.61.52.8-1.61.62.21.61.6-1.62.6-2.61.0-1.5-0.5-1.1
Delay discount hyperbolic model param0.30.42.2-0.3-1.00.0-0.0-1.5-0.20.0-0.0-0.40.40.1-0.11.21.1
Intermittent access intake day 1-15 change0.00.21.90.20.10.1-0.10.4-0.20.1-0.1-0.00.0-0.30.2-0.61.4
Intermittent access intake escalation0.10.31.31.00.6-0.50.50.20.40.7-0.70.1-0.10.00.3-0.71.1
Intermittent access intake escalation 20.10.20.9-0.10.10.4-0.40.8-0.3-0.20.20.0-0.0-0.60.5-1.00.8
Intermitt. access day 1 inactive lever presses0.00.61.6-1.3-0.60.9-0.90.8-0.8-1.01.00.5-0.5-0.6-0.50.30.9
Intermitt. access day 15 inactive lever presses0.10.51.30.50.8-0.50.50.40.50.6-0.61.2-1.20.7-0.90.4-0.3
Intermitt. access escalation Index1.13.35.3-2.0-2.32.1-2.1-0.5-2.2-2.02.0-2.22.2-1.71.2-0.31.3
Intermittent access day 1 total infusions0.30.83.2-0.5-0.60.6-0.6-0.9-0.7-0.50.5-1.41.4-0.51.2-0.3-1.8
Intermittent access day 15 total infusions0.10.20.80.50.2-0.20.2-0.40.10.3-0.3-0.80.8-0.20.9-0.6-0.5
Intermittent access terminal intake (last 3 days)0.20.31.00.80.8-0.60.60.00.50.6-0.6-0.30.30.10.5-0.6-1.0
Intermittent access total infusions0.20.31.70.50.4-0.30.3-0.40.20.3-0.3-0.50.5-0.00.7-0.4-1.3
Intermittent access day 1 locomotion0.10.31.30.2-0.3-0.20.2-1.10.30.3-0.3-0.60.60.40.10.7-0.7
Intermittent access day 15 total locomotion0.10.50.80.90.7-0.80.8-0.10.90.9-0.90.7-0.70.9-0.80.50.2
Intermittent access total locomotion0.40.40.80.90.6-0.80.8-0.50.90.9-0.90.2-0.20.7-0.30.4-0.5
Intermittent access standard deviation0.63.14.62.11.9-2.02.0-0.12.12.1-2.11.8-1.82.0-1.50.9-0.3
Left kidney weight1.411.115.73.53.5-3.73.70.43.63.5-3.54.0-4.03.8-3.82.30.6
Right kidney weight1.510.215.93.12.9-3.43.4-0.03.33.4-3.43.8-3.83.9-4.02.80.7
Cocaine induced anxiety0.20.51.3-0.9-0.80.9-0.90.0-0.9-0.80.8-0.60.6-0.4-0.10.31.1
Post-drug Anxiety0.10.10.8-0.00.10.1-0.10.3-0.20.1-0.10.4-0.40.3-0.60.30.9
Baseline Anxiety0.20.31.00.50.7-0.50.50.30.40.5-0.51.0-1.00.4-0.40.0-0.5
Tail length1.16.018.71.63.9-1.71.74.31.81.7-1.73.4-3.41.3-2.4-1.2-0.6
Length with tail1.67.116.31.63.7-2.02.03.62.11.9-1.94.0-4.02.2-3.50.3-1.0
Length without tail1.05.115.51.01.6-1.71.70.51.91.6-1.63.2-3.22.9-3.92.9-0.3
Times rat made contact with spout0.50.52.40.6-0.1-0.10.1-0.60.20.1-0.1-1.11.1-0.51.5-1.2-0.5
Lifetime Intake0.30.32.40.50.5-0.40.4-0.30.30.5-0.5-0.40.40.10.5-0.3-1.6
Liver weight, left0.50.92.7-0.40.70.0-0.01.6-0.2-0.30.31.5-1.50.4-1.60.51.0
Liver weight, right0.50.94.4-0.70.80.4-0.42.1-0.5-0.40.41.4-1.40.0-1.3-0.10.4
Locomotor activity0.81.35.00.71.8-0.70.72.20.60.7-0.71.3-1.30.1-0.8-1.01.2
Locomotor testing distance0.20.51.60.31.0-0.40.41.30.10.4-0.40.9-0.90.0-0.8-0.21.1
Locomotor testing rearing0.20.82.00.50.9-0.80.80.50.60.9-0.91.2-1.20.7-1.40.80.6
Locomotion in novel chamber0.00.00.30.20.1-0.30.3-0.10.20.1-0.1-0.20.20.1-0.10.00.5
Locomotion in novel chamber post-restriction0.61.82.81.41.2-1.51.5-0.31.41.7-1.71.4-1.41.4-1.41.1-0.3
Fecal boli incidents, locomotor time 10.10.41.60.1-0.1-0.30.3-1.30.50.5-0.50.2-0.20.5-0.31.1-0.9
Change in fecal boli incidents, locomotor task0.40.52.6-0.60.10.5-0.51.6-0.7-0.60.60.6-0.6-0.3-0.6-0.40.8
Time >=10cm from walls, locomotor time 11.01.34.80.10.4-0.50.50.30.50.7-0.71.7-1.71.3-2.21.71.3
Bouts of movement, locomotor time 10.81.11.7-0.8-1.01.1-1.10.0-1.1-1.31.3-1.11.1-1.01.0-0.71.1
Total resting periods, locomotor time 10.70.81.4-0.8-0.91.0-1.00.1-1.0-1.21.2-0.80.8-0.90.8-0.60.8
Rest time, locomotor task time 10.10.10.4-0.10.5-0.10.10.70.00.0-0.00.6-0.6-0.1-0.1-0.3-0.1
Distance moved, locomotor task time 10.00.10.40.50.3-0.40.40.10.50.4-0.40.1-0.10.6-0.50.20.1
Vertical activity count, locomotor time 10.10.50.90.90.3-0.80.8-0.50.90.9-0.90.4-0.41.0-0.80.80.1
Time >=10cm from walls, locomotor time 20.41.13.30.31.0-0.50.51.00.40.7-0.71.8-1.81.0-1.70.8-0.7
Bouts of movement, locomotor time 20.10.41.70.20.70.1-0.11.3-0.1-0.20.20.3-0.3-0.50.4-1.30.8
Total resting periods, locomotor time 20.20.73.1-0.20.60.4-0.41.8-0.4-0.60.60.2-0.2-0.80.6-1.70.8
Rest time, locomotor task time 20.50.92.4-1.6-1.21.2-1.20.3-1.2-1.21.2-0.30.3-0.7-0.10.21.1
Distance moved, locomotor task time 21.01.32.61.30.7-1.21.2-0.81.31.3-1.30.6-0.61.6-0.91.1-1.6
Vertical activity count, locomotor time 20.51.22.51.00.8-1.21.2-0.51.21.2-1.20.8-0.81.3-0.91.0-1.6
Light reinforcement 10.20.84.70.2-0.7-0.10.1-1.1-0.00.3-0.30.2-0.20.9-1.01.62.2
Light reinforcement 20.20.42.0-0.3-0.50.2-0.2-0.7-0.3-0.10.10.4-0.40.6-1.01.41.0
Bone: marrow area1.43.410.80.42.5-1.11.13.31.01.0-1.02.9-2.91.1-2.6-0.00.1
Bone: maximum diameter0.71.43.5-1.6-0.31.4-1.41.9-1.3-1.51.50.2-0.2-1.1-0.0-0.90.9
Bone: maximum force0.81.52.81.20.9-1.31.3-0.31.31.1-1.11.4-1.41.7-1.61.40.4
Bone: maximum moment0.71.42.31.11.0-1.31.3-0.11.31.0-1.01.4-1.41.5-1.51.20.0
Mean time between licks in bursts0.31.73.4-1.8-0.71.5-1.51.6-1.5-1.61.6-0.50.5-1.60.6-1.20.8
Mean num. licks in bursts0.51.43.41.80.8-1.41.4-1.41.31.6-1.60.1-0.11.00.20.3-1.1
Cd content in liver0.80.94.90.2-0.8-0.40.4-2.20.50.1-0.10.0-0.01.1-0.51.9-1.4
Co content in liver1.61.93.41.40.9-1.51.5-1.01.51.2-1.21.5-1.51.9-1.41.6-0.7
Cu content in liver0.60.72.40.2-0.70.4-0.4-1.0-0.2-0.40.4-1.41.4-0.81.5-0.70.5
Fe content in liver1.11.32.71.30.6-1.41.4-1.11.31.5-1.50.5-0.51.7-0.91.2-0.0
K content in liver0.90.91.7-1.0-1.31.0-1.0-0.6-0.9-1.21.2-1.01.0-0.70.8-0.10.2
Mg content in liver2.62.95.1-2.3-1.72.2-2.20.6-2.2-2.22.2-1.01.0-1.60.9-0.71.2
Mn content in liver2.02.35.2-2.3-1.42.0-2.01.0-2.0-2.12.1-0.70.7-1.30.1-0.20.4
Na content in liver0.40.51.40.1-0.30.3-0.30.2-0.2-0.40.4-1.01.0-0.60.9-1.01.2
Rb content in liver0.30.41.3-0.7-1.10.4-0.4-1.1-0.3-0.30.3-0.60.6-0.2-0.00.9-0.4
Se content in liver3.13.76.6-2.0-0.52.3-2.32.6-2.3-2.22.2-0.80.8-2.21.4-2.50.6
Sr content in liver0.50.41.70.30.6-0.70.70.20.70.2-0.20.6-0.60.9-0.80.5-1.3
Zn content in liver0.10.10.5-0.5-0.20.3-0.30.0-0.4-0.40.40.3-0.3-0.1-0.10.2-0.7
Bone: minimum diameter0.40.73.1-1.00.30.6-0.61.8-0.6-0.70.71.0-1.0-0.4-1.1-0.00.5
Time in familiar zone, hab. session 10.60.72.40.6-0.5-0.20.2-1.50.20.2-0.2-1.31.3-0.41.5-0.5-0.7
Time in novel zone, hab. session 10.80.92.90.11.1-0.30.31.60.40.3-0.31.7-1.70.6-1.60.30.4
Total zone transitions, hab. session 10.60.81.9-0.9-1.01.0-1.0-0.2-0.9-1.01.0-0.90.9-1.00.7-0.31.4
Total locomotion distance, hab. session 10.60.81.6-1.0-1.30.9-0.9-0.7-0.9-0.90.9-1.01.0-1.00.70.11.0
Locomotion velocity, hab. session 10.30.51.1-0.7-0.80.7-0.7-0.3-0.7-0.70.7-0.70.7-0.90.6-0.11.1
Time in familiar zone, hab. session 20.50.55.60.80.0-0.50.5-0.60.50.4-0.4-0.10.10.30.10.02.4
Time in novel zone, hab. session 20.60.76.70.20.8-0.40.40.50.40.5-0.50.6-0.60.3-0.3-0.1-2.6
Total zone transitions, hab. session 20.60.73.8-0.6-1.20.6-0.6-0.9-0.5-0.50.5-0.80.8-0.3-0.00.82.0
Total locomotion distance, hab. session 21.62.15.2-1.4-2.31.3-1.3-1.7-1.2-1.21.2-1.61.6-1.00.60.92.0
Locomotion velocity, hab. session 22.12.86.3-1.7-2.51.7-1.7-1.5-1.6-1.61.6-1.91.9-1.40.90.62.0
Novel to familiar place preference ratio0.20.21.1-0.2-0.10.1-0.10.3-0.1-0.20.2-0.80.8-0.30.6-0.7-1.0
Novelty place preference0.20.21.0-0.10.20.0-0.00.60.0-0.00.0-0.50.5-0.30.5-0.9-1.0
Time in novel zone, NPP test0.20.31.10.10.5-0.10.10.90.20.1-0.1-0.30.3-0.20.4-1.0-1.0
Total zone transitions, NPP test1.21.83.9-1.5-2.01.5-1.5-1.3-1.5-1.51.5-1.51.5-1.21.10.30.4
Total locomotion distance, NPP test1.31.85.2-1.4-2.31.2-1.2-2.2-1.1-1.11.1-1.51.5-0.70.71.3-0.4
Locomotion velocity, NPP test2.13.08.1-1.8-2.81.6-1.6-2.5-1.5-1.51.5-1.91.9-1.01.01.30.0
Intraocular pressure0.20.42.40.4-0.6-0.30.3-1.50.20.2-0.2-0.90.90.40.20.8-0.3
Delta distance traveled before/after self-admin2.02.26.01.52.4-1.41.42.01.41.5-1.51.6-1.60.6-0.6-1.2-0.4
Delta ambulatory time before/after self-admin0.91.54.11.12.0-1.11.12.01.11.1-1.11.4-1.40.3-0.5-1.20.0
Parametrial fat weight1.43.28.91.70.2-1.61.6-2.41.81.7-1.71.0-1.02.4-2.03.01.2
Pavlov. Cond. lever latency4.86.09.23.01.8-3.03.0-1.43.02.9-2.92.1-2.13.0-2.22.10.9
Pavlov. Cond. magazine entry latency2.73.47.3-1.8-0.62.0-2.02.1-2.0-1.91.9-1.51.5-2.31.9-2.7-0.3
Pavlov. Cond. change in total contacts1.51.63.8-1.2-0.21.3-1.31.7-1.3-1.31.3-0.80.8-1.71.2-1.9-0.2
Pavlov. Cond. index score4.65.88.4-2.8-1.52.8-2.81.8-2.8-2.82.8-2.12.1-2.92.2-2.4-0.7
Pavlov. Cond. latency score4.86.28.9-2.9-1.62.9-2.91.9-2.9-2.82.8-2.22.2-3.02.2-2.5-0.5
Pavlov. Cond. lever contacts4.25.18.9-3.0-1.92.8-2.81.0-2.8-2.72.7-1.91.9-2.61.6-1.3-0.8
Pavlov. Cond. magazine entry number1.82.24.51.50.5-1.61.6-1.61.61.6-1.61.2-1.21.9-1.62.10.3
Pavlov. Cond. intertrial magazine entries0.91.15.41.0-0.2-1.11.1-2.31.00.8-0.80.0-0.01.1-0.31.7-0.4
Pavlov. Cond. lever-magazine prob. diff.4.65.78.3-2.8-1.52.8-2.81.7-2.8-2.82.8-2.12.1-2.92.2-2.4-0.7
Pavlov. Cond. response bias3.13.95.8-2.3-1.22.3-2.31.5-2.3-2.32.3-1.61.6-2.41.8-2.0-0.5
Pavlov. Cond. lever latency0.20.20.5-0.7-0.60.4-0.40.2-0.4-0.50.50.2-0.2-0.1-0.60.60.7
Pavlov. Cond. magazine entry latency0.10.20.8-0.4-0.10.2-0.20.3-0.4-0.30.3-0.20.2-0.50.4-0.4-0.9
Pavlov. Cond. change in total contacts0.20.51.30.81.1-0.70.70.60.60.6-0.60.3-0.30.10.3-0.9-0.7
Pavlov. Cond. index score0.10.20.90.20.5-0.20.20.50.10.1-0.1-0.00.0-0.30.5-0.8-0.9
Pavlov. Cond. latency score0.10.20.80.40.7-0.40.40.40.30.4-0.40.1-0.1-0.10.3-0.7-0.9
Pavlov. Cond. lever contacts0.10.20.50.70.6-0.50.5-0.10.40.5-0.5-0.00.00.20.5-0.5-0.5
Pavlov. Cond. magazine entry number0.00.10.50.10.10.1-0.10.20.1-0.00.00.2-0.20.1-0.1-0.10.7
Pavlov. Cond. intertrial magazine entries0.71.63.9-1.2-0.71.5-1.51.1-1.4-1.41.4-0.70.7-1.20.8-1.22.0
Pavlov. Cond. lever-magazine prob. diff.0.10.10.90.20.5-0.20.20.30.10.1-0.1-0.00.0-0.20.4-0.6-1.0
Pavlov. Cond. response bias0.10.20.7-0.00.00.1-0.10.1-0.2-0.20.2-0.50.5-0.40.8-0.8-0.7
Time in closed arm before self-admin0.00.10.5-0.00.40.0-0.00.70.1-0.00.00.3-0.3-0.0-0.2-0.3-0.2
Time in closed arm after self-admin0.10.10.20.10.2-0.30.3-0.10.40.1-0.10.1-0.10.4-0.40.4-0.4
Time in open arm before self-admin0.60.72.3-0.6-0.10.6-0.60.9-0.6-0.80.8-0.80.8-1.11.2-1.5-0.5
Time in open arm after self-admin0.20.20.80.40.8-0.30.30.70.20.4-0.40.1-0.1-0.30.4-0.9-0.6
Bone: periosteal estimation0.92.16.20.51.9-0.80.82.50.80.6-0.62.3-2.30.8-2.0-0.10.9
Bone: periosteal perimeter0.30.63.7-0.60.50.4-0.41.9-0.5-0.50.50.9-0.9-0.4-0.6-0.60.8
Bone: post-yield work0.20.30.9-0.8-0.20.2-0.20.6-0.3-0.40.40.7-0.70.2-1.00.60.2
Progressive ratio test 1 active lever presses0.10.22.00.10.2-0.10.1-0.30.10.2-0.2-0.10.10.20.10.1-1.4
Progressive ratio test 1 breakpoint0.10.21.90.10.3-0.10.1-0.20.10.2-0.2-0.10.10.20.10.1-1.4
Progressive ratio test 1 inactive lever presses0.20.42.30.3-0.5-0.40.4-1.50.60.5-0.5-0.10.10.7-0.31.2-0.1
Progressive ratio test 2 active lever presses0.20.41.0-0.2-0.60.4-0.4-0.7-0.5-0.30.3-1.01.0-0.50.9-0.3-0.2
Progressive ratio test 2 breakpoint0.30.41.1-0.1-0.60.4-0.4-0.7-0.4-0.20.2-1.01.0-0.51.0-0.3-0.2
Progressive ratio test 2 inactive lever presses0.10.31.8-0.7-0.20.6-0.60.0-0.7-0.40.4-0.00.0-0.40.3-0.0-1.3
Incentive Sensitization - Responses0.30.81.3-0.6-0.80.9-0.9-0.0-0.8-0.70.7-1.11.1-1.01.1-0.91.1
Incentive Sensitization - Breakpoint0.30.81.4-0.5-0.90.8-0.8-0.3-0.8-0.60.6-1.21.2-0.91.1-0.71.2
Sum of active levers in priming session hrs 5-60.20.20.7-0.20.50.0-0.00.7-0.1-0.10.10.3-0.3-0.40.3-0.7-0.8
Progressive ratio1.85.58.42.82.4-2.92.90.32.82.6-2.62.2-2.22.5-2.41.11.4
Food seeking constrained by brief footshock0.20.30.90.60.6-0.70.7-0.10.80.6-0.6-0.10.10.40.2-0.2-1.0
Seeking ratio, punishment vs. effort1.53.34.6-2.1-1.52.1-2.10.3-2.0-2.02.0-1.61.6-2.12.1-1.5-1.4
Retroperitoneal fat weight0.10.62.90.3-0.5-0.30.3-1.70.60.3-0.30.2-0.20.9-0.71.70.2
Reaction time number correct0.82.74.22.01.4-2.02.0-0.82.02.0-2.01.5-1.51.8-1.21.2-0.3
Reaction time mean minus median0.42.84.5-2.0-1.51.9-1.90.5-2.0-2.12.1-1.71.7-1.91.3-1.00.3
Reaction time mean minus median AUC0.42.94.6-2.1-1.62.0-2.00.1-2.0-2.12.1-1.71.7-1.81.5-0.8-1.0
Reaction time num false alarms0.40.61.5-0.8-0.30.7-0.71.2-0.7-0.70.7-0.40.4-0.90.4-1.11.2
Reaction time num false alarms AUC0.40.83.3-0.60.10.7-0.71.8-0.5-0.60.6-0.10.1-1.00.4-1.51.5
Reaction time trials correct on left0.82.74.22.01.4-2.02.0-0.82.02.0-2.01.5-1.51.8-1.21.2-0.3
Reaction time trials on left0.82.74.12.01.4-2.02.0-0.81.92.0-2.01.6-1.61.8-1.21.1-0.3
Reaction time mean1.43.16.5-2.6-2.12.2-2.2-0.1-2.2-2.42.4-1.41.4-1.60.8-0.0-0.8
Reaction time mean AUC1.23.06.0-2.5-2.02.1-2.1-0.1-2.2-2.32.3-1.41.4-1.50.8-0.1-1.0
Median of all reaction times1.32.04.6-2.1-1.81.7-1.7-0.3-1.7-1.91.9-0.90.9-1.10.40.4-1.1
Reaction time omissions1.11.83.5-1.9-1.51.6-1.60.1-1.7-1.81.8-1.11.1-1.30.5-0.10.6
Reaction time false alarm rate1.92.65.0-1.8-0.61.7-1.72.2-1.6-1.71.7-1.01.0-2.01.1-2.11.3
Reaction time premature initiation rate0.40.61.10.60.7-0.70.7-0.10.90.8-0.80.9-0.90.9-1.00.9-0.9
Reaction time premature initiations1.02.94.01.81.6-1.81.8-0.52.02.0-2.01.8-1.82.0-1.81.5-0.9
Std. dev. reaction times0.93.05.1-2.2-1.22.1-2.11.2-2.1-2.32.3-1.31.3-2.11.2-1.4-0.2
Reaction time trials completed0.82.74.12.01.4-2.02.0-0.81.92.0-2.01.6-1.61.8-1.21.1-0.3
Reaction time trials AUC0.72.53.71.91.3-1.91.9-0.91.91.9-1.91.5-1.51.8-1.21.2-0.3
Run reversals in cocaine runway, females0.50.51.00.70.2-0.90.9-1.01.00.8-0.80.1-0.10.7-0.30.8-0.6
Run reversals in cocaine runway, males0.40.40.9-0.9-0.50.8-0.80.4-0.9-0.80.8-0.30.3-0.90.4-0.40.2
Latency to leave start box in cocaine runway1.01.32.6-1.6-1.41.4-1.40.1-1.4-1.51.5-0.90.9-1.20.5-0.1-0.0
Latency to leave start box in cocaine runway, F0.91.11.9-1.4-1.31.2-1.2-0.2-1.1-1.31.3-1.21.2-1.00.6-0.1-0.1
Latency to leave start box in cocaine runway, M0.20.20.5-0.6-0.50.6-0.60.2-0.7-0.60.60.2-0.2-0.4-0.20.10.4
Std. dev. time between licks in bursts0.71.35.1-1.6-0.01.2-1.22.2-1.4-1.31.30.3-0.3-0.9-0.1-1.00.8
Total sessions with >9 infusions0.30.31.70.60.8-0.50.50.30.40.5-0.50.0-0.00.10.4-0.7-1.3
Short access day 1 total inactive lever presses0.20.44.3-0.50.30.2-0.20.6-0.2-0.30.30.4-0.4-0.10.0-0.2-2.1
Short access day 10 total inactive lever presses0.21.34.5-1.2-1.61.2-1.2-0.6-1.1-1.11.1-0.80.8-0.70.40.32.1
Short access day 1 total infusions0.20.33.8-0.10.40.1-0.10.2-0.1-0.00.0-0.20.2-0.20.5-0.5-2.0
Short access day 10 total infusions0.10.20.90.2-0.1-0.10.1-0.8-0.00.2-0.2-0.70.7-0.00.6-0.0-1.0
Short access total infusions0.30.44.00.20.4-0.20.2-0.30.10.3-0.3-0.30.30.10.5-0.2-2.0
Short access day 1 locomotion0.81.42.0-1.2-1.41.4-1.4-0.3-1.3-1.31.3-1.41.4-1.21.1-0.40.5
Short access day 10 total locomotion0.31.23.40.51.4-0.50.51.80.50.6-0.61.7-1.70.7-1.5-0.11.3
Short access total locomotion0.10.10.3-0.20.30.1-0.10.5-0.1-0.10.10.4-0.40.2-0.50.2-0.1
One hour access (0.3 mA shock)2.32.85.0-1.4-2.01.6-1.6-0.7-1.7-1.61.6-2.22.2-1.91.7-0.81.3
Compulsive drug intake3.65.210.1-2.8-2.92.8-2.80.1-2.8-2.62.6-1.61.6-2.30.7-0.03.2
One hour access (shock baseline)0.30.72.61.00.5-0.90.9-0.90.70.8-0.8-0.60.60.40.7-0.3-1.6
Social response proportion0.50.71.70.31.2-0.30.31.20.20.5-0.51.3-1.30.6-1.10.2-0.7
Social responses0.50.62.20.51.3-0.40.41.50.30.5-0.51.2-1.20.2-0.8-0.40.3
Social time2.13.29.0-2.2-1.62.1-2.11.0-2.2-2.12.1-1.01.0-1.70.4-0.63.0
Soleus weight0.61.77.2-2.2-0.21.3-1.32.7-1.4-1.31.30.8-0.8-0.5-1.2-0.3-0.6
Bone: stiffness0.40.82.00.80.1-0.90.9-0.90.90.6-0.60.5-0.51.1-1.01.21.4
Tibialis anterior weight0.10.40.91.00.2-0.70.7-1.00.70.6-0.6-0.20.20.8-0.20.70.3
Time to tail flick, vehicle, before self-admin1.51.97.3-1.1-2.11.3-1.3-0.9-1.3-1.21.2-1.31.3-0.80.60.32.7
Time to tail flick, vehicle, after self-admin0.40.71.2-1.0-0.71.1-1.10.6-1.0-0.90.9-0.80.8-1.00.8-0.8-0.1
Time to tail flick, test, before self-admin0.40.42.60.2-0.10.1-0.10.2-0.20.0-0.0-1.01.0-0.60.7-0.81.6
Time to tail flick, test, after self-admin1.21.33.3-0.8-1.00.9-0.9-0.3-0.7-0.90.9-1.81.8-1.21.8-1.20.2
Delta time to tail flick, vehicle, before/after SA0.50.66.2-0.10.20.0-0.0-0.1-0.0-0.00.0-0.50.5-0.40.9-0.7-2.5
Delta time to tail flick, test, before/after SA0.30.42.0-0.4-1.00.3-0.3-1.4-0.2-0.30.3-0.70.70.10.40.7-0.6
Tibia length1.02.87.70.52.0-1.01.02.10.90.9-0.92.8-2.81.2-2.70.91.0
Ambulatory time before self-admin0.10.20.9-0.3-0.50.3-0.3-0.4-0.5-0.10.1-0.30.3-0.1-0.20.60.9
Ambulatory time after self-admin0.71.12.20.91.5-0.80.81.30.61.0-1.01.4-1.40.6-1.0-0.11.2
Bone: tissue strength0.40.41.10.40.3-0.50.5-0.60.60.4-0.40.6-0.61.0-0.71.0-1.1
Total heroin consumption0.10.11.0-0.3-0.00.3-0.30.5-0.2-0.30.3-0.00.0-0.30.1-0.41.0
Bone: trabecular number1.12.07.9-0.7-2.20.8-0.8-2.8-0.8-0.80.8-2.12.1-0.71.50.80.3
Bone: trabecular spacing1.72.55.80.92.2-1.01.02.41.01.1-1.12.3-2.31.0-1.8-0.3-1.5
Bone: trabecular thickness0.81.15.9-0.4-1.70.4-0.4-2.4-0.3-0.50.5-1.41.4-0.00.81.00.8
Bone: trabecular tissue density0.40.72.60.71.3-0.70.71.60.80.5-0.50.3-0.3-0.10.2-1.4-0.9
Water consumed over 24 hours0.10.20.4-0.6-0.20.6-0.60.6-0.5-0.50.5-0.00.0-0.40.0-0.30.2
Number of responses in last shaping day0.81.06.6-0.31.30.2-0.22.6-0.3-0.20.21.1-1.1-0.5-0.4-1.3-0.6