Hub : Genes

LOC108349032

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	alternative TSS	XR_010060960.1	0.04	0.02	1.0e-04	0.03	0.03	0.02	0.02	5.9e-04	2.8e-04	1.2e-03	1.2e-03
2	Adipose	isoform ratio	XR_010060959.1	0.02	0.02	4.6e-03	0.01	0.01	0	0	7.1e-02	1.1e-02	1.0e-01	8.7e-02
3	PL	alternative TSS	XR_010060960.1	0.03	0.02	3.1e-03	0.02	0.01	0.01	0.01	1.9e-03	2.8e-02	5.9e-02	3.6e-02
4	PL	alternative TSS	XR_010060958.1	0.03	0.02	2.3e-03	0.03	0.01	0.01	0.01	6.4e-04	2.3e-02	5.1e-02	1.3e-02
5	Adipose	gene expression	LOC108349032	0.03	0.02	8.3e-03	0	0.02	0.01	0.01	1.0e-01	4.4e-03	9.7e-03	3.0e-02
6	Liver	alternative TSS	XR_010060958.1	0.03	0.02	2.7e-04	0.03	0.03	0.03	0.03	2.6e-04	3.0e-04	4.5e-04	5.6e-04
7	Liver	alternative TSS	XR_010060958.1	0.03	0.02	4.5e-04	0.05	0.04	0.04	0.04	4.5e-06	5.3e-05	3.3e-05	1.4e-05
8	Liver	alternative TSS	XR_010060960.1	0.03	0.02	2.2e-03	0.03	0.03	0.02	0.02	1.2e-04	5.0e-04	1.7e-03	1.6e-03
9	pVTA	alternative TSS	XR_010060958.1	0.04	0.03	6.1e-03	0.01	0.01	0.01	0	2.4e-02	7.1e-02	1.1e-01	2.8e-01
10	pVTA	alternative TSS	XR_010060960.1	0.04	0.03	5.3e-03	0.03	0.01	0	0	3.8e-03	8.4e-02	1.6e-01	3.1e-01
11	Liver	isoform ratio	XR_010060959.1	0.04	0.02	1.1e-03	0.01	0.01	0.02	0.01	8.0e-03	6.8e-03	3.6e-03	3.9e-02
12	BLA	alternative TSS	XR_010060958.1	0.07	0.04	4.4e-03	0.04	0.04	0.04	0.04	5.4e-03	2.8e-03	5.5e-03	5.0e-03
13	PL	gene expression	LOC108349032	0.06	0.03	2.7e-04	0.01	0.03	0.02	0.02	1.5e-02	2.3e-04	1.3e-03	1.9e-03
14	Liver	gene expression	LOC108349032	0.21	0.1	1.7e-03	0.04	0	0.04	0.04	1.6e-05	1.2e-01	1.7e-05	2.8e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14
Bone: apparent density	0.9	1.5	5.5	-0.6	-1.9	-0.7	0.7	-2.3	0.7	0.7	-0.7	1.8	-1.8	0.5	1.2	0.7	-0.6
Area under the delay curve	0.2	0.3	1.4	0.1	0.6	-0.1	0.1	1.1	-0.1	0.1	-0.1	-0.2	0.2	0.0	0.1	-0.8	1.2
BMI with tail	1.4	4.7	9.1	2.1	0.9	2.2	-2.2	-1.9	-2.2	-2.2	2.2	-2.0	2.0	-2.9	-2.5	3.0	-1.4
BMI without tail	2.6	7.9	10.8	3.3	3.2	3.2	-3.2	0.3	-3.1	-3.2	3.2	-3.2	3.2	-2.9	-2.7	1.4	-0.7
Body weight	2.5	11.0	19.3	2.9	3.2	3.3	-3.3	0.6	-3.4	-3.2	3.2	-4.4	4.4	-3.9	-4.4	2.7	-0.4
Weight adjusted by age	2.5	3.8	8.5	1.4	2.3	1.6	-1.6	1.0	-1.7	-1.8	1.8	-2.9	2.9	-2.0	-2.3	1.1	1.4
Bone surface	0.1	0.2	2.3	-0.3	-0.3	-0.1	0.1	0.1	0.2	0.2	-0.2	0.0	-0.0	0.0	-0.3	0.2	-1.5
Bone volume	0.1	0.2	1.2	0.1	-0.4	0.1	-0.1	-0.9	-0.2	-0.0	0.0	0.3	-0.3	-0.3	-0.1	0.7	-1.1
Breakpoint value in progressive ratio session	0.3	0.4	0.6	-0.6	-0.4	-0.5	0.5	0.4	0.5	0.7	-0.7	0.8	-0.8	0.8	0.6	-0.7	-0.6
Number of licking bursts	0.9	1.4	2.3	-1.5	-0.8	-1.4	1.4	1.4	1.3	1.5	-1.5	0.5	-0.5	1.3	0.5	-1.0	-1.1
Context. condit. distance diff. score	4.6	5.6	10.7	-3.3	-2.7	-3.0	3.0	-0.1	2.9	3.0	-3.0	1.9	-1.9	2.4	1.6	-0.5	-0.3
Locomotion velocity, session 1	0.8	0.9	1.9	-0.9	-0.1	-1.0	1.0	1.0	1.0	0.9	-0.9	0.4	-0.4	1.2	1.1	-1.4	0.9
Locomotion distance, session 1	0.8	1.0	2.1	-0.8	-1.5	-1.0	1.0	-1.3	1.0	0.9	-0.9	1.3	-1.3	0.9	1.2	0.0	-0.4
Locomotion velocity, session 2	0.8	1.0	1.8	-1.1	-0.7	-1.3	1.3	0.5	1.3	1.0	-1.0	0.7	-0.7	1.1	0.9	-0.9	-0.5
Locomotion distance, session 2	1.5	2.1	4.3	-1.6	-2.1	-1.7	1.7	-1.3	1.7	1.5	-1.5	1.5	-1.5	1.1	1.1	0.3	0.2
Locomotion velocity, session 3	0.2	0.2	0.7	0.8	0.7	0.5	-0.5	0.1	-0.5	-0.4	0.4	-0.2	0.2	0.0	0.3	-0.5	-0.4
Locomotion distance, session 3	1.7	1.8	2.9	-1.1	-1.5	-1.4	1.4	-0.8	1.4	1.5	-1.5	1.6	-1.6	1.6	1.7	-0.6	-0.1
Stereotopy head waving bouts, day 3	0.5	0.6	3.2	0.0	1.0	0.3	-0.3	1.8	-0.3	-0.2	0.2	-1.3	1.3	-0.1	-0.9	-0.4	-0.2
Stereotopy head waving duration, day 3	1.2	1.5	3.8	0.8	1.8	1.0	-1.0	2.0	-1.0	-1.0	1.0	-1.7	1.7	-0.4	-1.0	-0.6	0.4
Locomotion velocity, session 7	4.9	5.4	10.8	-2.4	-3.3	-2.4	2.4	-2.3	2.4	2.5	-2.5	2.7	-2.7	2.0	2.0	0.3	0.9
Locomotion distance, session 7	5.1	6.4	11.3	-2.4	-3.1	-2.5	2.5	-1.8	2.4	2.7	-2.7	3.4	-3.4	2.6	2.8	-0.7	1.0
Stereotopy head waving bouts, day 7	0.8	0.9	3.9	0.6	1.4	0.5	-0.5	2.0	-0.5	-0.3	0.3	-0.7	0.7	0.4	0.4	-1.9	0.1
Stereotopy head waving duration, day 7	0.7	0.9	2.5	0.8	1.5	0.7	-0.7	1.6	-0.8	-0.7	0.7	-1.1	1.1	-0.1	-0.1	-1.2	-0.1
Locomotion velocity, session 8	2.6	3.1	5.9	-2.4	-0.9	-2.3	2.3	2.1	2.2	2.2	-2.2	0.4	-0.4	2.2	0.7	-1.5	-0.3
Locomotion distance, session 8	5.6	8.1	14.3	-3.7	-3.8	-3.5	3.5	-1.2	3.5	3.5	-3.5	2.5	-2.5	2.6	1.7	0.2	-0.4
Degree of sensitization distance	0.4	0.4	1.1	-1.0	-0.6	-0.8	0.8	0.5	0.8	0.9	-0.9	0.5	-0.5	0.5	0.1	-0.2	-0.1
Degree of sensitization stereotypy	0.5	0.5	3.2	0.2	0.7	-0.1	0.1	1.3	0.0	0.1	-0.1	0.0	-0.0	0.8	1.0	-1.8	-0.2
Conditioned locomotion	0.3	0.4	1.6	0.0	0.1	0.3	-0.3	0.0	-0.4	-0.2	0.2	-0.8	0.8	-0.8	-1.2	1.1	-0.5
Cocaine response after cond. corrected	1.2	1.4	4.1	-1.3	-2.0	-1.1	1.1	-1.4	1.0	1.0	-1.0	1.2	-1.2	0.3	-0.1	1.3	-1.4
Cocaine response after cond. not corrected	0.3	0.4	1.8	-0.8	-0.5	-0.6	0.6	0.5	0.6	0.6	-0.6	-0.0	0.0	0.1	-0.6	0.4	-1.3
Cocaine response before conditioning	3.3	3.9	11.1	1.6	3.3	1.4	-1.4	3.3	-1.4	-1.4	1.4	-2.8	2.8	-0.9	-1.4	-1.4	0.3
Saline control response	4.9	6.5	11.2	3.3	3.0	3.2	-3.2	0.2	-3.2	-3.3	3.3	-2.0	2.0	-2.6	-1.6	0.4	0.2
Bone: connectivity density	0.8	1.3	4.8	-0.8	-2.0	-0.8	0.8	-2.2	0.8	0.6	-0.6	1.3	-1.3	0.2	0.6	1.1	-0.7
Bone: cortical apparent density	1.2	1.6	2.5	1.6	0.5	1.5	-1.5	-1.3	-1.6	-1.4	1.4	-0.6	0.6	-1.6	-1.0	1.4	-0.8
Bone: cortical area	0.1	0.2	1.3	0.1	0.3	0.0	-0.0	0.7	-0.0	0.2	-0.2	-0.6	0.6	-0.0	-0.4	-0.1	-1.1
Bone: cortical porosity	1.4	1.5	7.2	0.7	1.9	0.3	-0.3	2.5	-0.3	-0.2	0.2	-0.4	0.4	0.7	0.9	-2.7	1.5
Bone: cortical porosity	1.5	1.6	7.2	0.3	1.7	0.0	-0.0	2.7	0.0	0.0	-0.0	-0.5	0.5	0.7	0.8	-2.6	1.9
Bone: cortical thickness	0.4	0.7	1.7	1.3	0.4	0.9	-0.9	-0.9	-1.0	-0.8	0.8	-0.4	0.4	-0.7	-0.3	0.5	-1.2
Bone: cortical thickness	1.1	1.2	2.8	1.7	0.6	1.3	-1.3	-1.2	-1.3	-1.3	1.3	-0.5	0.5	-1.2	-0.6	0.9	-0.8
Bone: cortical tissue density	1.1	1.5	2.5	1.5	0.6	1.5	-1.5	-1.2	-1.6	-1.4	1.4	-0.6	0.6	-1.5	-1.0	1.3	-0.7
Condit. Reinf. active minus inactive responses	0.7	0.8	2.2	-0.4	-0.1	-0.8	0.8	0.6	0.8	0.8	-0.8	0.6	-0.6	1.1	1.4	-1.5	1.0
Condit. Reinf. active-inactive response ratio	0.2	0.3	0.7	0.8	0.9	0.4	-0.4	0.4	-0.4	-0.4	0.4	-0.5	0.5	-0.1	0.2	-0.7	0.4
Condit. Reinf. active responses	0.6	0.8	1.9	-0.6	-0.7	-0.9	0.9	-0.5	0.9	0.8	-0.8	1.1	-1.1	1.0	1.4	-0.7	0.7
Condit. Reinf. inactive responses	1.4	1.8	4.6	-0.8	-1.8	-0.9	0.9	-2.0	1.0	0.9	-0.9	2.2	-2.2	0.9	1.5	0.3	-0.1
Incentive salience index mean	2.5	3.1	4.9	-2.0	-1.6	-2.2	2.2	0.3	2.2	2.1	-2.1	1.5	-1.5	1.9	1.7	-1.1	0.6
Condit. Reinf. lever presses	4.2	5.9	10.5	-3.2	-3.1	-3.0	3.0	-0.6	3.0	2.9	-2.9	2.3	-2.3	2.2	1.4	-0.0	-0.3
Condit. Reinf. active minus inactive responses	0.8	1.1	3.3	1.0	1.8	0.9	-0.9	1.5	-0.8	-0.8	0.8	-1.4	1.4	-0.5	-0.7	-0.5	0.4
Condit. Reinf. active-inactive response ratio	1.0	1.1	3.7	0.6	1.8	0.7	-0.7	1.9	-0.6	-0.7	0.7	-1.6	1.6	-0.4	-0.9	-0.6	0.3
Condit. Reinf. active responses	0.3	0.4	1.3	0.7	1.1	0.6	-0.6	0.7	-0.6	-0.5	0.5	-0.7	0.7	-0.3	-0.3	-0.4	0.2
Condit. Reinf. inactive responses	0.1	0.1	0.4	0.6	0.1	0.4	-0.4	-0.6	-0.5	-0.3	0.3	0.1	-0.1	-0.4	0.1	0.2	-0.2
Condit. Reinf. lever presses	0.1	0.2	0.9	0.1	0.5	-0.1	0.1	0.5	0.1	0.1	-0.1	0.1	-0.1	0.4	0.8	-1.0	0.4
Condit. Reinf. lever reinforcers received	0.2	0.3	1.2	0.5	1.1	0.4	-0.4	1.0	-0.3	-0.3	0.3	-0.6	0.6	0.0	0.0	-0.8	0.1
Conditioned reinforcement - actives	0.1	0.2	0.3	0.5	0.3	0.4	-0.4	-0.6	-0.2	-0.6	0.6	0.0	-0.0	-0.3	-0.1	0.4	0.4
Conditioned reinforcement - inactives	0.3	0.5	1.6	0.7	0.8	0.8	-0.8	-0.2	-0.7	-0.9	0.9	-0.4	0.4	-0.7	-0.2	0.2	1.3
Conditioned locomotion	0.1	0.1	1.3	0.1	0.3	0.2	-0.2	-0.1	-0.0	-0.2	0.2	-0.1	0.1	-0.4	-0.1	0.2	1.2
Patch foraging indifference point 0 sec	2.0	3.8	6.4	2.5	2.2	2.5	-2.5	-0.1	-2.3	-2.5	2.5	-1.3	1.3	-2.2	-1.3	0.6	0.8
Patch foraging indifference point AUC	0.3	0.4	2.1	0.3	0.8	0.1	-0.1	1.5	-0.1	-0.2	0.2	-0.0	0.0	0.2	0.3	-1.3	-0.5
Delay disc. indifference point, 0s delay	0.3	0.3	0.8	-0.9	-0.5	-0.7	0.7	0.4	0.7	0.8	-0.8	0.2	-0.2	0.5	0.1	-0.2	0.8
Delay disc. indifference point, 16s delay	0.2	0.2	0.9	0.7	0.6	0.5	-0.5	0.0	-0.5	-0.3	0.3	-0.1	0.1	-0.5	0.2	-0.4	0.9
Delay disc. indifference point, 2s delay	0.6	0.7	3.9	-0.1	1.2	-0.2	0.2	2.0	0.0	-0.0	0.0	-0.8	0.8	0.2	-0.3	-1.1	1.4
Delay disc. indifference point, 24s delay	0.8	0.8	2.7	0.9	1.5	0.7	-0.7	1.3	-0.8	-0.5	0.5	-0.8	0.8	-0.5	-0.1	-1.0	1.7
Delay disc. indifference point, 4s delay	0.6	0.7	2.5	0.7	1.4	0.5	-0.5	1.6	-0.7	-0.5	0.5	-0.9	0.9	-0.4	-0.7	-0.7	0.3
Delay disc. indifference point, 8s delay	0.2	0.3	1.6	-0.3	-0.0	-0.4	0.4	0.5	0.3	0.4	-0.4	0.3	-0.3	0.3	0.4	-0.7	1.3
Indifference point function ln k	0.4	0.8	1.5	-1.0	-0.4	-0.9	0.9	1.0	0.9	1.2	-1.2	0.4	-0.4	1.1	0.6	-1.0	0.1
Indifference point function log k	0.4	0.8	1.5	-1.0	-0.4	-0.9	0.9	1.0	0.9	1.2	-1.2	0.4	-0.4	1.1	0.6	-1.0	0.1
Patch foraging total patch changes 0 sec	2.1	3.9	6.9	2.6	2.2	2.6	-2.6	-0.2	-2.4	-2.6	2.6	-1.2	1.2	-2.3	-1.3	0.6	0.9
Patch foraging total patch changes 12 sec	1.7	2.2	4.3	2.0	1.7	1.9	-1.9	0.2	-1.7	-2.1	2.1	-0.9	0.9	-1.4	-0.8	0.1	-0.5
Patch foraging total patch changes 18 sec	1.6	2.4	4.3	2.1	0.6	1.9	-1.9	-1.9	-1.7	-2.1	2.1	-0.1	0.1	-1.9	-0.7	1.4	-0.8
Patch foraging total patch changes 24 sec	0.5	0.9	3.3	1.1	-0.1	1.0	-1.0	-1.8	-1.0	-0.9	0.9	0.7	-0.7	-0.9	0.4	0.6	0.7
Patch foraging total patch changes 6 sec	2.0	3.1	5.4	2.3	1.8	2.2	-2.2	-0.4	-2.1	-2.3	2.3	-1.1	1.1	-2.1	-1.0	0.6	1.0
Patch foraging time to switch 0 sec	0.7	1.5	7.3	0.5	-0.8	0.7	-0.7	-2.6	-0.6	-0.5	0.5	-0.5	0.5	-1.4	-1.2	2.7	-0.6
Patch foraging water rate 0 sec	0.2	0.3	1.3	0.4	0.7	0.6	-0.6	0.5	-0.6	-0.5	0.5	-0.4	0.4	-0.6	-0.5	-0.0	1.2
Patch foraging water rate 12 sec	0.1	0.2	0.6	0.3	-0.4	0.2	-0.2	-0.8	-0.4	0.0	-0.0	0.7	-0.7	0.1	0.5	0.0	-0.1
Patch foraging water rate 18 sec	0.3	0.4	1.3	0.7	0.6	0.9	-0.9	-0.1	-1.1	-0.5	0.5	-0.4	0.4	-0.5	-0.4	0.2	1.1
Patch foraging water rate 24 sec	0.2	0.2	0.9	0.6	0.3	0.7	-0.7	-0.3	-1.0	-0.4	0.4	0.1	-0.1	-0.4	-0.2	0.2	-0.3
Patch foraging water rate 6 sec	0.0	0.1	0.2	0.3	-0.1	0.3	-0.3	-0.4	-0.3	-0.1	0.1	0.3	-0.3	-0.1	0.0	0.1	-0.0
Seeking ratio, delayed vs. immediate footshock	0.9	1.2	5.1	1.2	1.4	0.9	-0.9	1.6	-0.9	-0.7	0.7	-0.3	0.3	-0.1	-0.3	-1.1	-2.3
Distance traveled before self-admin	0.3	0.4	2.1	-0.3	-0.6	-0.2	0.2	-0.5	0.4	0.1	-0.1	-0.1	0.1	-0.3	-0.9	1.2	-1.4
Distance traveled after self-admin	1.1	1.3	2.9	1.0	1.3	0.9	-0.9	1.1	-0.8	-1.0	1.0	-1.6	1.6	-0.8	-1.4	0.2	-1.7
Extensor digitorum longus weight	0.0	0.2	0.8	-0.5	0.0	-0.2	0.2	0.5	0.2	0.4	-0.4	-0.3	0.3	-0.2	-0.6	0.4	0.9
Bone: elastic displacement	0.3	0.4	2.7	0.7	0.6	0.5	-0.5	-0.1	-0.4	-0.6	0.6	0.3	-0.3	-0.1	0.6	-0.6	1.6
Bone: elastic work	0.2	0.3	0.8	0.6	0.7	0.5	-0.5	0.2	-0.5	-0.6	0.6	-0.4	0.4	-0.5	-0.3	-0.1	0.9
Bone: endosteal estimation	1.4	3.0	11.0	0.2	2.3	0.9	-0.9	3.3	-0.8	-0.7	0.7	-2.8	2.8	-0.9	-2.4	-0.1	-0.1
Bone: endosteal perimeter	0.5	1.1	5.5	-1.3	0.3	-0.9	0.9	2.4	0.9	1.0	-1.0	-1.0	1.0	0.5	-1.0	-0.4	-0.7
Epididymis fat weight	4.0	13.8	28.1	4.5	1.1	4.3	-4.3	-5.3	-4.4	-4.2	4.2	-1.4	1.4	-4.6	-2.4	4.6	-0.5
Delta time in closed arm before/after self-admin	0.5	0.5	1.2	0.3	0.4	0.5	-0.5	-0.2	-0.5	-0.5	0.5	-0.9	0.9	-0.9	-1.1	1.0	0.3
Delta time in open arm before/after self-admin	0.2	0.2	0.5	0.7	0.6	0.5	-0.5	-0.3	-0.4	-0.7	0.7	-0.0	0.0	-0.2	0.1	-0.0	0.3
Diff in mean of infusions in LGA sessions	2.8	3.4	7.5	-2.0	-2.7	-2.0	2.0	-1.3	1.9	1.8	-1.8	2.4	-2.4	1.5	1.4	0.0	-0.6
Delay discount exponential model param	0.3	0.4	1.6	-0.2	-0.8	0.0	-0.0	-1.3	0.2	-0.1	0.1	0.3	-0.3	-0.0	-0.0	1.0	-1.2
Extinction: sum of active levers before priming	0.6	0.7	1.3	-1.1	-0.7	-1.1	1.1	0.5	1.1	1.1	-1.1	0.5	-0.5	0.8	0.3	-0.4	0.1
Active lever presses in extinction session 6	0.3	0.3	3.0	0.4	0.2	0.4	-0.4	-0.7	-0.4	-0.4	0.4	0.2	-0.2	-0.4	0.2	0.3	1.7
Bone: final force	1.5	2.4	4.2	1.6	1.0	1.6	-1.6	-0.6	-1.7	-1.6	1.6	-1.6	1.6	-2.1	-1.9	1.7	-0.9
Bone: final moment	1.4	2.2	3.8	1.5	1.1	1.6	-1.6	-0.5	-1.7	-1.5	1.5	-1.5	1.5	-1.9	-1.7	1.5	-0.5
Food consumed during 24 hour testing period	0.2	0.3	1.6	-0.4	-0.3	-0.0	0.0	-0.1	-0.1	-0.1	0.1	-0.6	0.6	-0.5	-1.3	1.3	-0.3
Glucose	2.1	3.2	6.7	-2.6	-0.6	-2.1	2.1	2.5	2.1	2.2	-2.2	0.1	-0.1	2.0	0.4	-1.4	1.6
Heart weight	2.1	3.2	7.6	1.5	2.8	1.6	-1.6	2.2	-1.6	-1.6	1.6	-2.6	2.6	-1.0	-1.5	-0.5	1.1
Delay discount hyperbolic model param	0.4	0.4	2.2	-0.3	-1.0	-0.0	0.0	-1.5	0.2	-0.0	0.0	0.4	-0.4	-0.1	-0.1	1.2	-1.1
Intermittent access intake day 1-15 change	0.1	0.2	1.9	0.2	0.1	-0.1	0.1	0.4	0.2	-0.1	0.1	0.0	-0.0	0.3	0.2	-0.6	-1.4
Intermittent access intake escalation	0.2	0.3	1.3	1.0	0.6	0.5	-0.5	0.2	-0.4	-0.7	0.7	-0.1	0.1	-0.0	0.3	-0.7	-1.1
Intermittent access intake escalation 2	0.2	0.2	0.9	-0.1	0.1	-0.4	0.4	0.8	0.3	0.2	-0.2	-0.0	0.0	0.6	0.5	-1.0	-0.8
Intermitt. access day 1 inactive lever presses	0.2	0.6	1.6	-1.3	-0.6	-0.9	0.9	0.8	0.8	1.0	-1.0	-0.5	0.5	0.6	-0.5	0.3	-0.9
Intermitt. access day 15 inactive lever presses	0.2	0.5	1.3	0.5	0.8	0.5	-0.5	0.4	-0.5	-0.6	0.6	-1.2	1.2	-0.7	-0.9	0.4	0.3
Intermitt. access escalation Index	2.4	3.3	5.3	-2.0	-2.3	-2.1	2.1	-0.5	2.2	2.0	-2.0	2.2	-2.2	1.7	1.2	-0.3	-1.3
Intermittent access day 1 total infusions	0.5	0.8	3.2	-0.5	-0.6	-0.6	0.6	-0.9	0.7	0.5	-0.5	1.4	-1.4	0.5	1.2	-0.3	1.8
Intermittent access day 15 total infusions	0.2	0.2	0.8	0.5	0.2	0.2	-0.2	-0.4	-0.1	-0.3	0.3	0.8	-0.8	0.2	0.9	-0.6	0.5
Intermittent access terminal intake (last 3 days)	0.3	0.3	1.0	0.8	0.8	0.6	-0.6	0.0	-0.5	-0.6	0.6	0.3	-0.3	-0.1	0.5	-0.6	1.0
Intermittent access total infusions	0.2	0.3	1.7	0.5	0.4	0.3	-0.3	-0.4	-0.2	-0.3	0.3	0.5	-0.5	0.0	0.7	-0.4	1.3
Intermittent access day 1 locomotion	0.2	0.3	1.3	0.2	-0.3	0.2	-0.2	-1.1	-0.3	-0.3	0.3	0.6	-0.6	-0.4	0.1	0.7	0.7
Intermittent access day 15 total locomotion	0.3	0.5	0.8	0.9	0.7	0.8	-0.8	-0.1	-0.9	-0.9	0.9	-0.7	0.7	-0.9	-0.8	0.5	-0.2
Intermittent access total locomotion	0.4	0.4	0.8	0.9	0.6	0.8	-0.8	-0.5	-0.9	-0.9	0.9	-0.2	0.2	-0.7	-0.3	0.4	0.5
Intermittent access standard deviation	1.5	3.1	4.6	2.1	1.9	2.0	-2.0	-0.1	-2.1	-2.1	2.1	-1.8	1.8	-2.0	-1.5	0.9	0.3
Left kidney weight	2.4	11.1	15.7	3.5	3.5	3.7	-3.7	0.4	-3.6	-3.5	3.5	-4.0	4.0	-3.8	-3.8	2.3	-0.6
Right kidney weight	2.2	10.2	15.9	3.1	2.9	3.4	-3.4	-0.0	-3.3	-3.4	3.4	-3.8	3.8	-3.9	-4.0	2.8	-0.7
Cocaine induced anxiety	0.4	0.5	1.3	-0.9	-0.8	-0.9	0.9	0.0	0.9	0.8	-0.8	0.6	-0.6	0.4	-0.1	0.3	-1.1
Post-drug Anxiety	0.1	0.1	0.8	-0.0	0.1	-0.1	0.1	0.3	0.2	-0.1	0.1	-0.4	0.4	-0.3	-0.6	0.3	-0.9
Baseline Anxiety	0.3	0.3	1.0	0.5	0.7	0.5	-0.5	0.3	-0.4	-0.5	0.5	-1.0	1.0	-0.4	-0.4	0.0	0.5
Tail length	1.5	6.0	18.7	1.6	3.9	1.7	-1.7	4.3	-1.8	-1.7	1.7	-3.4	3.4	-1.3	-2.4	-1.2	0.6
Length with tail	1.6	7.1	16.3	1.6	3.7	2.0	-2.0	3.6	-2.1	-1.9	1.9	-4.0	4.0	-2.2	-3.5	0.3	1.0
Length without tail	1.6	5.1	15.5	1.0	1.6	1.7	-1.7	0.5	-1.9	-1.6	1.6	-3.2	3.2	-2.9	-3.9	2.9	0.3
Times rat made contact with spout	0.5	0.5	2.4	0.6	-0.1	0.1	-0.1	-0.6	-0.2	-0.1	0.1	1.1	-1.1	0.5	1.5	-1.2	0.5
Lifetime Intake	0.3	0.3	2.4	0.5	0.5	0.4	-0.4	-0.3	-0.3	-0.5	0.5	0.4	-0.4	-0.1	0.5	-0.3	1.6
Liver weight, left	0.5	0.9	2.7	-0.4	0.7	-0.0	0.0	1.6	0.2	0.3	-0.3	-1.5	1.5	-0.4	-1.6	0.5	-1.0
Liver weight, right	0.5	0.9	4.4	-0.7	0.8	-0.4	0.4	2.1	0.5	0.4	-0.4	-1.4	1.4	-0.0	-1.3	-0.1	-0.4
Locomotor activity	0.8	1.3	5.0	0.7	1.8	0.7	-0.7	2.2	-0.6	-0.7	0.7	-1.3	1.3	-0.1	-0.8	-1.0	-1.2
Locomotor testing distance	0.3	0.5	1.6	0.3	1.0	0.4	-0.4	1.3	-0.1	-0.4	0.4	-0.9	0.9	-0.0	-0.8	-0.2	-1.1
Locomotor testing rearing	0.4	0.8	2.0	0.5	0.9	0.8	-0.8	0.5	-0.6	-0.9	0.9	-1.2	1.2	-0.7	-1.4	0.8	-0.6
Locomotion in novel chamber	0.0	0.0	0.3	0.2	0.1	0.3	-0.3	-0.1	-0.2	-0.1	0.1	0.2	-0.2	-0.1	-0.1	0.0	-0.5
Locomotion in novel chamber post-restriction	1.1	1.8	2.8	1.4	1.2	1.5	-1.5	-0.3	-1.4	-1.7	1.7	-1.4	1.4	-1.4	-1.4	1.1	0.3
Fecal boli incidents, locomotor time 1	0.3	0.4	1.6	0.1	-0.1	0.3	-0.3	-1.3	-0.5	-0.5	0.5	-0.2	0.2	-0.5	-0.3	1.1	0.9
Change in fecal boli incidents, locomotor task	0.5	0.5	2.6	-0.6	0.1	-0.5	0.5	1.6	0.7	0.6	-0.6	-0.6	0.6	0.3	-0.6	-0.4	-0.8
Time >=10cm from walls, locomotor time 1	1.2	1.3	4.8	0.1	0.4	0.5	-0.5	0.3	-0.5	-0.7	0.7	-1.7	1.7	-1.3	-2.2	1.7	-1.3
Bouts of movement, locomotor time 1	0.9	1.1	1.7	-0.8	-1.0	-1.1	1.1	0.0	1.1	1.3	-1.3	1.1	-1.1	1.0	1.0	-0.7	-1.1
Total resting periods, locomotor time 1	0.7	0.8	1.4	-0.8	-0.9	-1.0	1.0	0.1	1.0	1.2	-1.2	0.8	-0.8	0.9	0.8	-0.6	-0.8
Rest time, locomotor task time 1	0.1	0.1	0.4	-0.1	0.5	0.1	-0.1	0.7	-0.0	-0.0	0.0	-0.6	0.6	0.1	-0.1	-0.3	0.1
Distance moved, locomotor task time 1	0.1	0.1	0.4	0.5	0.3	0.4	-0.4	0.1	-0.5	-0.4	0.4	-0.1	0.1	-0.6	-0.5	0.2	-0.1
Vertical activity count, locomotor time 1	0.2	0.5	0.9	0.9	0.3	0.8	-0.8	-0.5	-0.9	-0.9	0.9	-0.4	0.4	-1.0	-0.8	0.8	-0.1
Time >=10cm from walls, locomotor time 2	0.7	1.1	3.3	0.3	1.0	0.5	-0.5	1.0	-0.4	-0.7	0.7	-1.8	1.8	-1.0	-1.7	0.8	0.7
Bouts of movement, locomotor time 2	0.2	0.4	1.7	0.2	0.7	-0.1	0.1	1.3	0.1	0.2	-0.2	-0.3	0.3	0.5	0.4	-1.3	-0.8
Total resting periods, locomotor time 2	0.4	0.7	3.1	-0.2	0.6	-0.4	0.4	1.8	0.4	0.6	-0.6	-0.2	0.2	0.8	0.6	-1.7	-0.8
Rest time, locomotor task time 2	0.7	0.9	2.4	-1.6	-1.2	-1.2	1.2	0.3	1.2	1.2	-1.2	0.3	-0.3	0.7	-0.1	0.2	-1.1
Distance moved, locomotor task time 2	1.1	1.3	2.6	1.3	0.7	1.2	-1.2	-0.8	-1.3	-1.3	1.3	-0.6	0.6	-1.6	-0.9	1.1	1.6
Vertical activity count, locomotor time 2	0.8	1.2	2.5	1.0	0.8	1.2	-1.2	-0.5	-1.2	-1.2	1.2	-0.8	0.8	-1.3	-0.9	1.0	1.6
Light reinforcement 1	0.3	0.8	4.7	0.2	-0.7	0.1	-0.1	-1.1	0.0	-0.3	0.3	-0.2	0.2	-0.9	-1.0	1.6	-2.2
Light reinforcement 2	0.3	0.4	2.0	-0.3	-0.5	-0.2	0.2	-0.7	0.3	0.1	-0.1	-0.4	0.4	-0.6	-1.0	1.4	-1.0
Bone: marrow area	1.5	3.4	10.8	0.4	2.5	1.1	-1.1	3.3	-1.0	-1.0	1.0	-2.9	2.9	-1.1	-2.6	-0.0	-0.1
Bone: maximum diameter	0.7	1.4	3.5	-1.6	-0.3	-1.4	1.4	1.9	1.3	1.5	-1.5	-0.2	0.2	1.1	-0.0	-0.9	-0.9
Bone: maximum force	0.9	1.5	2.8	1.2	0.9	1.3	-1.3	-0.3	-1.3	-1.1	1.1	-1.4	1.4	-1.7	-1.6	1.4	-0.4
Bone: maximum moment	0.8	1.4	2.3	1.1	1.0	1.3	-1.3	-0.1	-1.3	-1.0	1.0	-1.4	1.4	-1.5	-1.5	1.2	-0.0
Mean time between licks in bursts	0.7	1.7	3.4	-1.8	-0.7	-1.5	1.5	1.6	1.5	1.6	-1.6	0.5	-0.5	1.6	0.6	-1.2	-0.8
Mean num. licks in bursts	0.9	1.4	3.4	1.8	0.8	1.4	-1.4	-1.4	-1.3	-1.6	1.6	-0.1	0.1	-1.0	0.2	0.3	1.1
Cd content in liver	0.8	0.9	4.9	0.2	-0.8	0.4	-0.4	-2.2	-0.5	-0.1	0.1	-0.0	0.0	-1.1	-0.5	1.9	1.4
Co content in liver	1.7	1.9	3.4	1.4	0.9	1.5	-1.5	-1.0	-1.5	-1.2	1.2	-1.5	1.5	-1.9	-1.4	1.6	0.7
Cu content in liver	0.6	0.7	2.4	0.2	-0.7	-0.4	0.4	-1.0	0.2	0.4	-0.4	1.4	-1.4	0.8	1.5	-0.7	-0.5
Fe content in liver	1.1	1.3	2.7	1.3	0.6	1.4	-1.4	-1.1	-1.3	-1.5	1.5	-0.5	0.5	-1.7	-0.9	1.2	0.0
K content in liver	0.9	0.9	1.7	-1.0	-1.3	-1.0	1.0	-0.6	0.9	1.2	-1.2	1.0	-1.0	0.7	0.8	-0.1	-0.2
Mg content in liver	2.8	2.9	5.1	-2.3	-1.7	-2.2	2.2	0.6	2.2	2.2	-2.2	1.0	-1.0	1.6	0.9	-0.7	-1.2
Mn content in liver	2.0	2.3	5.2	-2.3	-1.4	-2.0	2.0	1.0	2.0	2.1	-2.1	0.7	-0.7	1.3	0.1	-0.2	-0.4
Na content in liver	0.4	0.5	1.4	0.1	-0.3	-0.3	0.3	0.2	0.2	0.4	-0.4	1.0	-1.0	0.6	0.9	-1.0	-1.2
Rb content in liver	0.3	0.4	1.3	-0.7	-1.1	-0.4	0.4	-1.1	0.3	0.3	-0.3	0.6	-0.6	0.2	-0.0	0.9	0.4
Se content in liver	3.1	3.7	6.6	-2.0	-0.5	-2.3	2.3	2.6	2.3	2.2	-2.2	0.8	-0.8	2.2	1.4	-2.5	-0.6
Sr content in liver	0.5	0.4	1.7	0.3	0.6	0.7	-0.7	0.2	-0.7	-0.2	0.2	-0.6	0.6	-0.9	-0.8	0.5	1.3
Zn content in liver	0.1	0.1	0.5	-0.5	-0.2	-0.3	0.3	0.0	0.4	0.4	-0.4	-0.3	0.3	0.1	-0.1	0.2	0.7
Bone: minimum diameter	0.4	0.7	3.1	-1.0	0.3	-0.6	0.6	1.8	0.6	0.7	-0.7	-1.0	1.0	0.4	-1.1	-0.0	-0.5
Time in familiar zone, hab. session 1	0.7	0.7	2.4	0.6	-0.5	0.2	-0.2	-1.5	-0.2	-0.2	0.2	1.3	-1.3	0.4	1.5	-0.5	0.7
Time in novel zone, hab. session 1	0.9	0.9	2.9	0.1	1.1	0.3	-0.3	1.6	-0.4	-0.3	0.3	-1.7	1.7	-0.6	-1.6	0.3	-0.4
Total zone transitions, hab. session 1	0.6	0.8	1.9	-0.9	-1.0	-1.0	1.0	-0.2	0.9	1.0	-1.0	0.9	-0.9	1.0	0.7	-0.3	-1.4
Total locomotion distance, hab. session 1	0.6	0.8	1.6	-1.0	-1.3	-0.9	0.9	-0.7	0.9	0.9	-0.9	1.0	-1.0	1.0	0.7	0.1	-1.0
Locomotion velocity, hab. session 1	0.3	0.5	1.1	-0.7	-0.8	-0.7	0.7	-0.3	0.7	0.7	-0.7	0.7	-0.7	0.9	0.6	-0.1	-1.1
Time in familiar zone, hab. session 2	0.5	0.5	5.6	0.8	0.0	0.5	-0.5	-0.6	-0.5	-0.4	0.4	0.1	-0.1	-0.3	0.1	0.0	-2.4
Time in novel zone, hab. session 2	0.7	0.7	6.7	0.2	0.8	0.4	-0.4	0.5	-0.4	-0.5	0.5	-0.6	0.6	-0.3	-0.3	-0.1	2.6
Total zone transitions, hab. session 2	0.6	0.7	3.8	-0.6	-1.2	-0.6	0.6	-0.9	0.5	0.5	-0.5	0.8	-0.8	0.3	-0.0	0.8	-2.0
Total locomotion distance, hab. session 2	1.6	2.1	5.2	-1.4	-2.3	-1.3	1.3	-1.7	1.2	1.2	-1.2	1.6	-1.6	1.0	0.6	0.9	-2.0
Locomotion velocity, hab. session 2	2.1	2.8	6.3	-1.7	-2.5	-1.7	1.7	-1.5	1.6	1.6	-1.6	1.9	-1.9	1.4	0.9	0.6	-2.0
Novel to familiar place preference ratio	0.2	0.2	1.1	-0.2	-0.1	-0.1	0.1	0.3	0.1	0.2	-0.2	0.8	-0.8	0.3	0.6	-0.7	1.0
Novelty place preference	0.2	0.2	1.0	-0.1	0.2	-0.0	0.0	0.6	-0.0	0.0	-0.0	0.5	-0.5	0.3	0.5	-0.9	1.0
Time in novel zone, NPP test	0.2	0.3	1.1	0.1	0.5	0.1	-0.1	0.9	-0.2	-0.1	0.1	0.3	-0.3	0.2	0.4	-1.0	1.0
Total zone transitions, NPP test	1.3	1.8	3.9	-1.5	-2.0	-1.5	1.5	-1.3	1.5	1.5	-1.5	1.5	-1.5	1.2	1.1	0.3	-0.4
Total locomotion distance, NPP test	1.4	1.8	5.2	-1.4	-2.3	-1.2	1.2	-2.2	1.1	1.1	-1.1	1.5	-1.5	0.7	0.7	1.3	0.4
Locomotion velocity, NPP test	2.1	3.0	8.1	-1.8	-2.8	-1.6	1.6	-2.5	1.5	1.5	-1.5	1.9	-1.9	1.0	1.0	1.3	-0.0
Intraocular pressure	0.3	0.4	2.4	0.4	-0.6	0.3	-0.3	-1.5	-0.2	-0.2	0.2	0.9	-0.9	-0.4	0.2	0.8	0.3
Delta distance traveled before/after self-admin	2.0	2.2	6.0	1.5	2.4	1.4	-1.4	2.0	-1.4	-1.5	1.5	-1.6	1.6	-0.6	-0.6	-1.2	0.4
Delta ambulatory time before/after self-admin	1.2	1.5	4.1	1.1	2.0	1.1	-1.1	2.0	-1.1	-1.1	1.1	-1.4	1.4	-0.3	-0.5	-1.2	-0.0
Parametrial fat weight	1.4	3.2	8.9	1.7	0.2	1.6	-1.6	-2.4	-1.8	-1.7	1.7	-1.0	1.0	-2.4	-2.0	3.0	-1.2
Pavlov. Cond. lever latency	4.8	6.0	9.2	3.0	1.8	3.0	-3.0	-1.4	-3.0	-2.9	2.9	-2.1	2.1	-3.0	-2.2	2.1	-0.9
Pavlov. Cond. magazine entry latency	2.7	3.4	7.3	-1.8	-0.6	-2.0	2.0	2.1	2.0	1.9	-1.9	1.5	-1.5	2.3	1.9	-2.7	0.3
Pavlov. Cond. change in total contacts	1.5	1.6	3.8	-1.2	-0.2	-1.3	1.3	1.7	1.3	1.3	-1.3	0.8	-0.8	1.7	1.2	-1.9	0.2
Pavlov. Cond. index score	4.6	5.8	8.4	-2.8	-1.5	-2.8	2.8	1.8	2.8	2.8	-2.8	2.1	-2.1	2.9	2.2	-2.4	0.7
Pavlov. Cond. latency score	4.9	6.2	8.9	-2.9	-1.6	-2.9	2.9	1.9	2.9	2.8	-2.8	2.2	-2.2	3.0	2.2	-2.5	0.5
Pavlov. Cond. lever contacts	4.3	5.1	8.9	-3.0	-1.9	-2.8	2.8	1.0	2.8	2.7	-2.7	1.9	-1.9	2.6	1.6	-1.3	0.8
Pavlov. Cond. magazine entry number	1.8	2.2	4.5	1.5	0.5	1.6	-1.6	-1.6	-1.6	-1.6	1.6	-1.2	1.2	-1.9	-1.6	2.1	-0.3
Pavlov. Cond. intertrial magazine entries	0.9	1.1	5.4	1.0	-0.2	1.1	-1.1	-2.3	-1.0	-0.8	0.8	-0.0	0.0	-1.1	-0.3	1.7	0.4
Pavlov. Cond. lever-magazine prob. diff.	4.6	5.7	8.3	-2.8	-1.5	-2.8	2.8	1.7	2.8	2.8	-2.8	2.1	-2.1	2.9	2.2	-2.4	0.7
Pavlov. Cond. response bias	3.1	3.9	5.8	-2.3	-1.2	-2.3	2.3	1.5	2.3	2.3	-2.3	1.6	-1.6	2.4	1.8	-2.0	0.5
Pavlov. Cond. lever latency	0.2	0.2	0.5	-0.7	-0.6	-0.4	0.4	0.2	0.4	0.5	-0.5	-0.2	0.2	0.1	-0.6	0.6	-0.7
Pavlov. Cond. magazine entry latency	0.1	0.2	0.8	-0.4	-0.1	-0.2	0.2	0.3	0.4	0.3	-0.3	0.2	-0.2	0.5	0.4	-0.4	0.9
Pavlov. Cond. change in total contacts	0.3	0.5	1.3	0.8	1.1	0.7	-0.7	0.6	-0.6	-0.6	0.6	-0.3	0.3	-0.1	0.3	-0.9	0.7
Pavlov. Cond. index score	0.1	0.2	0.9	0.2	0.5	0.2	-0.2	0.5	-0.1	-0.1	0.1	0.0	-0.0	0.3	0.5	-0.8	0.9
Pavlov. Cond. latency score	0.2	0.2	0.8	0.4	0.7	0.4	-0.4	0.4	-0.3	-0.4	0.4	-0.1	0.1	0.1	0.3	-0.7	0.9
Pavlov. Cond. lever contacts	0.1	0.2	0.5	0.7	0.6	0.5	-0.5	-0.1	-0.4	-0.5	0.5	0.0	-0.0	-0.2	0.5	-0.5	0.5
Pavlov. Cond. magazine entry number	0.0	0.1	0.5	0.1	0.1	-0.1	0.1	0.2	-0.1	0.0	-0.0	-0.2	0.2	-0.1	-0.1	-0.1	-0.7
Pavlov. Cond. intertrial magazine entries	1.1	1.6	3.9	-1.2	-0.7	-1.5	1.5	1.1	1.4	1.4	-1.4	0.7	-0.7	1.2	0.8	-1.2	-2.0
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.9	0.2	0.5	0.2	-0.2	0.3	-0.1	-0.1	0.1	0.0	-0.0	0.2	0.4	-0.6	1.0
Pavlov. Cond. response bias	0.1	0.2	0.7	-0.0	0.0	-0.1	0.1	0.1	0.2	0.2	-0.2	0.5	-0.5	0.4	0.8	-0.8	0.7
Time in closed arm before self-admin	0.1	0.1	0.5	-0.0	0.4	-0.0	0.0	0.7	-0.1	0.0	-0.0	-0.3	0.3	0.0	-0.2	-0.3	0.2
Time in closed arm after self-admin	0.1	0.1	0.2	0.1	0.2	0.3	-0.3	-0.1	-0.4	-0.1	0.1	-0.1	0.1	-0.4	-0.4	0.4	0.4
Time in open arm before self-admin	0.6	0.7	2.3	-0.6	-0.1	-0.6	0.6	0.9	0.6	0.8	-0.8	0.8	-0.8	1.1	1.2	-1.5	0.5
Time in open arm after self-admin	0.2	0.2	0.8	0.4	0.8	0.3	-0.3	0.7	-0.2	-0.4	0.4	-0.1	0.1	0.3	0.4	-0.9	0.6
Bone: periosteal estimation	1.0	2.1	6.2	0.5	1.9	0.8	-0.8	2.5	-0.8	-0.6	0.6	-2.3	2.3	-0.8	-2.0	-0.1	-0.9
Bone: periosteal perimeter	0.4	0.6	3.7	-0.6	0.5	-0.4	0.4	1.9	0.5	0.5	-0.5	-0.9	0.9	0.4	-0.6	-0.6	-0.8
Bone: post-yield work	0.2	0.3	0.9	-0.8	-0.2	-0.2	0.2	0.6	0.3	0.4	-0.4	-0.7	0.7	-0.2	-1.0	0.6	-0.2
Progressive ratio test 1 active lever presses	0.1	0.2	2.0	0.1	0.2	0.1	-0.1	-0.3	-0.1	-0.2	0.2	0.1	-0.1	-0.2	0.1	0.1	1.4
Progressive ratio test 1 breakpoint	0.1	0.2	1.9	0.1	0.3	0.1	-0.1	-0.2	-0.1	-0.2	0.2	0.1	-0.1	-0.2	0.1	0.1	1.4
Progressive ratio test 1 inactive lever presses	0.3	0.4	2.3	0.3	-0.5	0.4	-0.4	-1.5	-0.6	-0.5	0.5	0.1	-0.1	-0.7	-0.3	1.2	0.1
Progressive ratio test 2 active lever presses	0.3	0.4	1.0	-0.2	-0.6	-0.4	0.4	-0.7	0.5	0.3	-0.3	1.0	-1.0	0.5	0.9	-0.3	0.2
Progressive ratio test 2 breakpoint	0.3	0.4	1.1	-0.1	-0.6	-0.4	0.4	-0.7	0.4	0.2	-0.2	1.0	-1.0	0.5	1.0	-0.3	0.2
Progressive ratio test 2 inactive lever presses	0.2	0.3	1.8	-0.7	-0.2	-0.6	0.6	0.0	0.7	0.4	-0.4	0.0	-0.0	0.4	0.3	-0.0	1.3
Incentive Sensitization - Responses	0.6	0.8	1.3	-0.6	-0.8	-0.9	0.9	-0.0	0.8	0.7	-0.7	1.1	-1.1	1.0	1.1	-0.9	-1.1
Incentive Sensitization - Breakpoint	0.6	0.8	1.4	-0.5	-0.9	-0.8	0.8	-0.3	0.8	0.6	-0.6	1.2	-1.2	0.9	1.1	-0.7	-1.2
Sum of active levers in priming session hrs 5-6	0.2	0.2	0.7	-0.2	0.5	-0.0	0.0	0.7	0.1	0.1	-0.1	-0.3	0.3	0.4	0.3	-0.7	0.8
Progressive ratio	3.5	5.5	8.4	2.8	2.4	2.9	-2.9	0.3	-2.8	-2.6	2.6	-2.2	2.2	-2.5	-2.4	1.1	-1.4
Food seeking constrained by brief footshock	0.2	0.3	0.9	0.6	0.6	0.7	-0.7	-0.1	-0.8	-0.6	0.6	0.1	-0.1	-0.4	0.2	-0.2	1.0
Seeking ratio, punishment vs. effort	2.3	3.3	4.6	-2.1	-1.5	-2.1	2.1	0.3	2.0	2.0	-2.0	1.6	-1.6	2.1	2.1	-1.5	1.4
Retroperitoneal fat weight	0.1	0.6	2.9	0.3	-0.5	0.3	-0.3	-1.7	-0.6	-0.3	0.3	-0.2	0.2	-0.9	-0.7	1.7	-0.2
Reaction time number correct	1.4	2.7	4.2	2.0	1.4	2.0	-2.0	-0.8	-2.0	-2.0	2.0	-1.5	1.5	-1.8	-1.2	1.2	0.3
Reaction time mean minus median	1.1	2.8	4.5	-2.0	-1.5	-1.9	1.9	0.5	2.0	2.1	-2.1	1.7	-1.7	1.9	1.3	-1.0	-0.3
Reaction time mean minus median AUC	1.1	2.9	4.6	-2.1	-1.6	-2.0	2.0	0.1	2.0	2.1	-2.1	1.7	-1.7	1.8	1.5	-0.8	1.0
Reaction time num false alarms	0.4	0.6	1.5	-0.8	-0.3	-0.7	0.7	1.2	0.7	0.7	-0.7	0.4	-0.4	0.9	0.4	-1.1	-1.2
Reaction time num false alarms AUC	0.5	0.8	3.3	-0.6	0.1	-0.7	0.7	1.8	0.5	0.6	-0.6	0.1	-0.1	1.0	0.4	-1.5	-1.5
Reaction time trials correct on left	1.4	2.7	4.2	2.0	1.4	2.0	-2.0	-0.8	-2.0	-2.0	2.0	-1.5	1.5	-1.8	-1.2	1.2	0.3
Reaction time trials on left	1.4	2.7	4.1	2.0	1.4	2.0	-2.0	-0.8	-1.9	-2.0	2.0	-1.6	1.6	-1.8	-1.2	1.1	0.3
Reaction time mean	2.0	3.1	6.5	-2.6	-2.1	-2.2	2.2	-0.1	2.2	2.4	-2.4	1.4	-1.4	1.6	0.8	-0.0	0.8
Reaction time mean AUC	1.9	3.0	6.0	-2.5	-2.0	-2.1	2.1	-0.1	2.2	2.3	-2.3	1.4	-1.4	1.5	0.8	-0.1	1.0
Median of all reaction times	1.4	2.0	4.6	-2.1	-1.8	-1.7	1.7	-0.3	1.7	1.9	-1.9	0.9	-0.9	1.1	0.4	0.4	1.1
Reaction time omissions	1.2	1.8	3.5	-1.9	-1.5	-1.6	1.6	0.1	1.7	1.8	-1.8	1.1	-1.1	1.3	0.5	-0.1	-0.6
Reaction time false alarm rate	1.9	2.6	5.0	-1.8	-0.6	-1.7	1.7	2.2	1.6	1.7	-1.7	1.0	-1.0	2.0	1.1	-2.1	-1.3
Reaction time premature initiation rate	0.5	0.6	1.1	0.6	0.7	0.7	-0.7	-0.1	-0.9	-0.8	0.8	-0.9	0.9	-0.9	-1.0	0.9	0.9
Reaction time premature initiations	1.6	2.9	4.0	1.8	1.6	1.8	-1.8	-0.5	-2.0	-2.0	2.0	-1.8	1.8	-2.0	-1.8	1.5	0.9
Std. dev. reaction times	1.6	3.0	5.1	-2.2	-1.2	-2.1	2.1	1.2	2.1	2.3	-2.3	1.3	-1.3	2.1	1.2	-1.4	0.2
Reaction time trials completed	1.4	2.7	4.1	2.0	1.4	2.0	-2.0	-0.8	-1.9	-2.0	2.0	-1.6	1.6	-1.8	-1.2	1.1	0.3
Reaction time trials AUC	1.3	2.5	3.7	1.9	1.3	1.9	-1.9	-0.9	-1.9	-1.9	1.9	-1.5	1.5	-1.8	-1.2	1.2	0.3
Run reversals in cocaine runway, females	0.5	0.5	1.0	0.7	0.2	0.9	-0.9	-1.0	-1.0	-0.8	0.8	-0.1	0.1	-0.7	-0.3	0.8	0.6
Run reversals in cocaine runway, males	0.4	0.4	0.9	-0.9	-0.5	-0.8	0.8	0.4	0.9	0.8	-0.8	0.3	-0.3	0.9	0.4	-0.4	-0.2
Latency to leave start box in cocaine runway	1.2	1.3	2.6	-1.6	-1.4	-1.4	1.4	0.1	1.4	1.5	-1.5	0.9	-0.9	1.2	0.5	-0.1	0.0
Latency to leave start box in cocaine runway, F	1.0	1.1	1.9	-1.4	-1.3	-1.2	1.2	-0.2	1.1	1.3	-1.3	1.2	-1.2	1.0	0.6	-0.1	0.1
Latency to leave start box in cocaine runway, M	0.2	0.2	0.5	-0.6	-0.5	-0.6	0.6	0.2	0.7	0.6	-0.6	-0.2	0.2	0.4	-0.2	0.1	-0.4
Std. dev. time between licks in bursts	1.0	1.3	5.1	-1.6	-0.0	-1.2	1.2	2.2	1.4	1.3	-1.3	-0.3	0.3	0.9	-0.1	-1.0	-0.8
Total sessions with >9 infusions	0.3	0.3	1.7	0.6	0.8	0.5	-0.5	0.3	-0.4	-0.5	0.5	-0.0	0.0	-0.1	0.4	-0.7	1.3
Short access day 1 total inactive lever presses	0.3	0.4	4.3	-0.5	0.3	-0.2	0.2	0.6	0.2	0.3	-0.3	-0.4	0.4	0.1	0.0	-0.2	2.1
Short access day 10 total inactive lever presses	0.5	1.3	4.5	-1.2	-1.6	-1.2	1.2	-0.6	1.1	1.1	-1.1	0.8	-0.8	0.7	0.4	0.3	-2.1
Short access day 1 total infusions	0.3	0.3	3.8	-0.1	0.4	-0.1	0.1	0.2	0.1	0.0	-0.0	0.2	-0.2	0.2	0.5	-0.5	2.0
Short access day 10 total infusions	0.2	0.2	0.9	0.2	-0.1	0.1	-0.1	-0.8	0.0	-0.2	0.2	0.7	-0.7	0.0	0.6	-0.0	1.0
Short access total infusions	0.3	0.4	4.0	0.2	0.4	0.2	-0.2	-0.3	-0.1	-0.3	0.3	0.3	-0.3	-0.1	0.5	-0.2	2.0
Short access day 1 locomotion	1.1	1.4	2.0	-1.2	-1.4	-1.4	1.4	-0.3	1.3	1.3	-1.3	1.4	-1.4	1.2	1.1	-0.4	-0.5
Short access day 10 total locomotion	0.7	1.2	3.4	0.5	1.4	0.5	-0.5	1.8	-0.5	-0.6	0.6	-1.7	1.7	-0.7	-1.5	-0.1	-1.3
Short access total locomotion	0.1	0.1	0.3	-0.2	0.3	-0.1	0.1	0.5	0.1	0.1	-0.1	-0.4	0.4	-0.2	-0.5	0.2	0.1
One hour access (0.3 mA shock)	2.4	2.8	5.0	-1.4	-2.0	-1.6	1.6	-0.7	1.7	1.6	-1.6	2.2	-2.2	1.9	1.7	-0.8	-1.3
Compulsive drug intake	4.4	5.2	10.1	-2.8	-2.9	-2.8	2.8	0.1	2.8	2.6	-2.6	1.6	-1.6	2.3	0.7	-0.0	-3.2
One hour access (shock baseline)	0.4	0.7	2.6	1.0	0.5	0.9	-0.9	-0.9	-0.7	-0.8	0.8	0.6	-0.6	-0.4	0.7	-0.3	1.6
Social response proportion	0.6	0.7	1.7	0.3	1.2	0.3	-0.3	1.2	-0.2	-0.5	0.5	-1.3	1.3	-0.6	-1.1	0.2	0.7
Social responses	0.5	0.6	2.2	0.5	1.3	0.4	-0.4	1.5	-0.3	-0.5	0.5	-1.2	1.2	-0.2	-0.8	-0.4	-0.3
Social time	2.4	3.2	9.0	-2.2	-1.6	-2.1	2.1	1.0	2.2	2.1	-2.1	1.0	-1.0	1.7	0.4	-0.6	-3.0
Soleus weight	0.6	1.7	7.2	-2.2	-0.2	-1.3	1.3	2.7	1.4	1.3	-1.3	-0.8	0.8	0.5	-1.2	-0.3	0.6
Bone: stiffness	0.5	0.8	2.0	0.8	0.1	0.9	-0.9	-0.9	-0.9	-0.6	0.6	-0.5	0.5	-1.1	-1.0	1.2	-1.4
Tibialis anterior weight	0.1	0.4	0.9	1.0	0.2	0.7	-0.7	-1.0	-0.7	-0.6	0.6	0.2	-0.2	-0.8	-0.2	0.7	-0.3
Time to tail flick, vehicle, before self-admin	1.8	1.9	7.3	-1.1	-2.1	-1.3	1.3	-0.9	1.3	1.2	-1.2	1.3	-1.3	0.8	0.6	0.3	-2.7
Time to tail flick, vehicle, after self-admin	0.6	0.7	1.2	-1.0	-0.7	-1.1	1.1	0.6	1.0	0.9	-0.9	0.8	-0.8	1.0	0.8	-0.8	0.1
Time to tail flick, test, before self-admin	0.4	0.4	2.6	0.2	-0.1	-0.1	0.1	0.2	0.2	-0.0	0.0	1.0	-1.0	0.6	0.7	-0.8	-1.6
Time to tail flick, test, after self-admin	1.2	1.3	3.3	-0.8	-1.0	-0.9	0.9	-0.3	0.7	0.9	-0.9	1.8	-1.8	1.2	1.8	-1.2	-0.2
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	6.2	-0.1	0.2	-0.0	0.0	-0.1	0.0	0.0	-0.0	0.5	-0.5	0.4	0.9	-0.7	2.5
Delta time to tail flick, test, before/after SA	0.4	0.4	2.0	-0.4	-1.0	-0.3	0.3	-1.4	0.2	0.3	-0.3	0.7	-0.7	-0.1	0.4	0.7	0.6
Tibia length	1.0	2.8	7.7	0.5	2.0	1.0	-1.0	2.1	-0.9	-0.9	0.9	-2.8	2.8	-1.2	-2.7	0.9	-1.0
Ambulatory time before self-admin	0.1	0.2	0.9	-0.3	-0.5	-0.3	0.3	-0.4	0.5	0.1	-0.1	0.3	-0.3	0.1	-0.2	0.6	-0.9
Ambulatory time after self-admin	0.9	1.1	2.2	0.9	1.5	0.8	-0.8	1.3	-0.6	-1.0	1.0	-1.4	1.4	-0.6	-1.0	-0.1	-1.2
Bone: tissue strength	0.4	0.4	1.1	0.4	0.3	0.5	-0.5	-0.6	-0.6	-0.4	0.4	-0.6	0.6	-1.0	-0.7	1.0	1.1
Total heroin consumption	0.1	0.1	1.0	-0.3	-0.0	-0.3	0.3	0.5	0.2	0.3	-0.3	0.0	-0.0	0.3	0.1	-0.4	-1.0
Bone: trabecular number	1.2	2.0	7.9	-0.7	-2.2	-0.8	0.8	-2.8	0.8	0.8	-0.8	2.1	-2.1	0.7	1.5	0.8	-0.3
Bone: trabecular spacing	1.8	2.5	5.8	0.9	2.2	1.0	-1.0	2.4	-1.0	-1.1	1.1	-2.3	2.3	-1.0	-1.8	-0.3	1.5
Bone: trabecular thickness	0.9	1.1	5.9	-0.4	-1.7	-0.4	0.4	-2.4	0.3	0.5	-0.5	1.4	-1.4	0.0	0.8	1.0	-0.8
Bone: trabecular tissue density	0.5	0.7	2.6	0.7	1.3	0.7	-0.7	1.6	-0.8	-0.5	0.5	-0.3	0.3	0.1	0.2	-1.4	0.9
Water consumed over 24 hours	0.1	0.2	0.4	-0.6	-0.2	-0.6	0.6	0.6	0.5	0.5	-0.5	0.0	-0.0	0.4	0.0	-0.3	-0.2
Number of responses in last shaping day	0.9	1.0	6.6	-0.3	1.3	-0.2	0.2	2.6	0.3	0.2	-0.2	-1.1	1.1	0.5	-0.4	-1.3	0.6