Hub : Genes

LOC103691200

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Eye gene expression LOC103691200 0.33 0.19 5.3e-03 0.11 0.11 0.14 0.11 1.0e-02 9.2e-03 3.9e-03 1.1e-02
2 OFC mRNA stability LOC103691200 0.25 0.15 5.9e-05 0.19 0.18 0.16 0.17 3.1e-05 3.9e-05 1.4e-04 8.5e-05
3 pVTA gene expression LOC103691200 0.11 0.08 8.7e-04 0.09 0.08 0.07 0.08 1.6e-04 3.3e-04 3.7e-04 3.2e-04
4 Brain mRNA stability LOC103691200 0.18 0.11 2.2e-16 0.19 0.19 0.18 0.18 3.6e-17 5.0e-17 1.1e-16 5.6e-17
5 IL mRNA stability LOC103691200 0.35 0.18 8.2e-06 0.06 0.08 0.09 0.08 1.9e-02 5.7e-03 4.0e-03 4.7e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5
Bone: apparent density0.10.20.3-0.2-0.50.4-0.30.6
Area under the delay curve0.20.20.4-0.50.6-0.40.30.1
BMI with tail0.10.20.4-0.40.3-0.60.5-0.3
BMI without tail0.91.84.20.01.3-1.31.2-2.0
Body weight0.72.95.4-0.31.6-1.81.7-2.3
Weight adjusted by age0.30.41.40.40.4-0.40.2-1.2
Bone surface0.61.11.51.2-1.20.9-0.8-1.1
Bone volume0.40.71.10.9-1.10.8-0.7-0.8
Breakpoint value in progressive ratio session0.20.30.9-0.4-0.30.3-0.20.9
Number of licking bursts4.95.88.3-2.92.4-2.52.61.3
Context. condit. distance diff. score3.34.06.72.0-2.62.0-2.0-1.2
Locomotion velocity, session 10.30.30.9-0.2-0.60.4-0.41.0
Locomotion distance, session 11.01.31.81.2-1.21.4-1.4-0.1
Locomotion velocity, session 20.00.00.10.30.10.1-0.1-0.0
Locomotion distance, session 20.40.50.90.8-0.60.9-0.9-0.2
Locomotion velocity, session 31.21.42.21.0-1.51.4-1.4-0.0
Locomotion distance, session 32.22.43.61.3-1.91.8-1.8-0.1
Stereotopy head waving bouts, day 30.60.71.1-0.71.0-1.01.0-0.2
Stereotopy head waving duration, day 30.10.10.20.3-0.40.4-0.40.2
Locomotion velocity, session 70.10.10.2-0.4-0.4-0.10.10.3
Locomotion distance, session 70.10.10.2-0.50.0-0.40.4-0.1
Stereotopy head waving bouts, day 72.52.93.71.9-1.71.9-1.9-0.6
Stereotopy head waving duration, day 72.53.14.52.1-1.71.9-1.9-0.9
Locomotion velocity, session 81.01.32.31.1-1.51.0-1.0-0.9
Locomotion distance, session 82.53.75.12.1-2.31.9-1.9-1.4
Degree of sensitization distance2.52.53.7-1.11.7-1.91.9-0.9
Degree of sensitization stereotypy5.35.87.92.8-2.42.7-2.7-1.0
Conditioned locomotion0.10.10.2-0.1-0.40.2-0.20.5
Cocaine response after cond. corrected2.32.63.5-1.71.7-1.91.80.1
Cocaine response after cond. not corrected0.50.60.8-0.90.8-0.90.90.1
Cocaine response before conditioning2.63.14.21.8-2.02.1-2.00.0
Saline control response1.11.42.61.6-0.80.7-0.7-1.6
Bone: connectivity density0.30.50.80.3-0.80.9-0.80.6
Bone: cortical apparent density2.12.83.7-1.91.8-1.91.80.2
Bone: cortical area0.40.62.20.6-0.6-0.0-0.0-1.5
Bone: cortical porosity1.51.62.51.2-1.61.4-1.4-0.1
Bone: cortical porosity1.31.42.31.1-1.51.4-1.30.0
Bone: cortical thickness0.10.10.2-0.5-0.3-0.30.20.0
Bone: cortical thickness0.40.51.20.5-1.10.6-0.6-0.3
Bone: cortical tissue density2.02.73.5-1.91.7-1.91.80.3
Condit. Reinf. active minus inactive responses0.20.20.70.20.4-0.30.3-0.9
Condit. Reinf. active-inactive response ratio0.40.41.80.50.1-0.20.2-1.3
Condit. Reinf. active responses0.10.10.3-0.10.5-0.30.3-0.3
Condit. Reinf. inactive responses0.10.10.3-0.20.30.0-0.00.6
Incentive salience index mean0.20.20.70.30.4-0.10.1-0.8
Condit. Reinf. lever presses0.00.10.20.20.20.1-0.1-0.4
Condit. Reinf. active minus inactive responses4.05.09.13.0-1.41.6-1.6-3.0
Condit. Reinf. active-inactive response ratio1.31.42.31.5-0.91.0-0.9-1.4
Condit. Reinf. active responses4.66.412.83.5-1.41.6-1.6-3.6
Condit. Reinf. inactive responses2.32.86.32.3-0.70.9-0.9-2.5
Condit. Reinf. lever presses11.615.728.05.3-3.23.4-3.4-4.2
Condit. Reinf. lever reinforcers received5.57.714.43.8-1.71.9-2.0-3.7
Conditioned reinforcement - actives3.33.34.42.0-2.02.0-2.1-0.5
Conditioned reinforcement - inactives0.20.30.5-0.40.5-0.70.7-0.2
Conditioned locomotion4.14.97.22.1-2.42.7-2.6-0.4
Patch foraging indifference point 0 sec2.94.77.42.7-2.12.2-2.2-1.5
Patch foraging indifference point AUC0.50.61.2-0.31.1-0.80.9-0.5
Delay disc. indifference point, 0s delay0.40.50.80.9-0.50.5-0.5-0.9
Delay disc. indifference point, 16s delay0.10.10.2-0.30.10.0-0.10.5
Delay disc. indifference point, 2s delay0.30.31.20.40.3-0.10.0-1.1
Delay disc. indifference point, 24s delay0.90.91.7-1.30.9-0.70.61.1
Delay disc. indifference point, 4s delay0.40.41.70.40.5-0.30.2-1.3
Delay disc. indifference point, 8s delay0.00.00.00.0-0.0-0.0-0.00.0
Indifference point function ln k2.53.45.01.6-2.22.1-2.20.3
Indifference point function log k2.53.45.01.6-2.22.1-2.20.3
Patch foraging total patch changes 0 sec2.23.65.72.4-1.71.9-1.9-1.4
Patch foraging total patch changes 12 sec0.40.51.50.80.3-0.0-0.0-1.2
Patch foraging total patch changes 18 sec0.91.22.61.6-0.80.9-0.7-1.2
Patch foraging total patch changes 24 sec0.40.51.90.90.3-0.00.1-1.4
Patch foraging total patch changes 6 sec0.40.60.90.9-0.60.8-0.9-0.3
Patch foraging time to switch 0 sec2.53.86.2-2.51.6-1.71.72.2
Patch foraging water rate 0 sec2.64.26.22.5-2.01.9-2.1-1.6
Patch foraging water rate 12 sec2.23.34.82.2-2.01.8-1.9-0.9
Patch foraging water rate 18 sec1.01.42.41.5-0.90.9-0.9-1.5
Patch foraging water rate 24 sec1.92.73.71.6-1.91.9-1.90.1
Patch foraging water rate 6 sec1.42.02.91.7-1.61.5-1.5-0.7
Seeking ratio, delayed vs. immediate footshock0.60.71.7-0.90.4-0.20.71.3
Distance traveled before self-admin1.21.32.0-1.41.3-1.10.90.8
Distance traveled after self-admin0.60.61.7-0.1-0.60.9-0.61.3
Extensor digitorum longus weight0.31.31.9-0.91.3-1.41.4-0.6
Bone: elastic displacement1.21.43.0-1.50.6-0.80.71.7
Bone: elastic work0.91.13.1-1.40.1-0.60.41.8
Bone: endosteal estimation0.71.55.51.3-0.20.1-0.0-2.4
Bone: endosteal perimeter0.91.96.41.6-0.50.5-0.4-2.5
Epididymis fat weight1.43.24.9-1.52.0-2.22.1-0.7
Delta time in closed arm before/after self-admin4.64.47.3-1.72.4-2.72.4-0.5
Delta time in open arm before/after self-admin3.13.04.72.2-1.61.6-1.4-1.7
Diff in mean of infusions in LGA sessions3.23.54.6-2.21.9-2.12.01.0
Delay discount exponential model param0.20.20.40.6-0.70.4-0.4-0.1
Extinction: sum of active levers before priming0.10.10.2-0.30.3-0.20.40.1
Active lever presses in extinction session 65.25.08.21.8-2.52.9-2.70.3
Bone: final force0.00.10.2-0.1-0.1-0.30.2-0.4
Bone: final moment0.10.10.40.1-0.3-0.10.0-0.7
Food consumed during 24 hour testing period4.04.86.22.5-2.42.4-2.3-1.0
Glucose0.10.20.40.2-0.60.4-0.40.1
Heart weight0.91.32.11.4-1.01.3-1.3-0.4
Delay discount hyperbolic model param0.20.20.40.4-0.70.4-0.40.2
Intermittent access intake day 1-15 change0.70.71.00.9-0.71.0-1.0-0.4
Intermittent access intake escalation0.90.91.41.0-0.81.2-1.1-0.4
Intermittent access intake escalation 20.10.10.50.30.20.1-0.2-0.7
Intermitt. access day 1 inactive lever presses0.50.50.9-0.60.8-0.90.9-0.2
Intermitt. access day 15 inactive lever presses0.30.30.50.5-0.70.6-0.50.2
Intermitt. access escalation Index0.30.20.30.5-0.40.5-0.5-0.4
Intermittent access day 1 total infusions0.91.02.01.4-1.00.9-0.6-1.0
Intermittent access day 15 total infusions1.71.92.91.7-1.41.6-1.3-0.8
Intermittent access terminal intake (last 3 days)1.31.42.21.5-1.11.3-1.1-0.9
Intermittent access total infusions0.91.01.91.4-1.00.9-0.7-0.9
Intermittent access day 1 locomotion0.30.30.50.5-0.70.7-0.50.1
Intermittent access day 15 total locomotion1.61.72.51.4-1.41.6-1.4-0.5
Intermittent access total locomotion0.70.71.11.1-1.01.0-0.7-0.5
Intermittent access standard deviation0.00.00.10.10.2-0.10.1-0.3
Left kidney weight0.51.34.80.70.7-0.60.4-2.2
Right kidney weight0.30.93.10.50.7-0.60.3-1.8
Cocaine induced anxiety1.72.03.5-1.91.3-1.31.21.4
Post-drug Anxiety1.11.21.6-1.21.3-1.31.20.3
Baseline Anxiety0.80.92.01.3-0.50.6-0.5-1.4
Tail length1.64.916.51.11.7-1.51.4-4.1
Length with tail1.24.210.50.31.9-1.81.9-3.2
Length without tail0.10.30.4-0.60.4-0.50.60.5
Times rat made contact with spout0.80.91.3-0.81.1-1.11.2-0.4
Lifetime Intake1.21.42.61.6-1.21.0-0.9-1.0
Liver weight, left1.62.64.1-1.22.0-1.91.9-0.5
Liver weight, right3.55.98.8-1.93.0-2.92.9-0.7
Locomotor activity0.50.71.40.9-0.71.0-1.2-0.2
Locomotor testing distance1.01.72.91.7-0.81.1-1.4-1.3
Locomotor testing rearing0.20.31.00.50.5-0.30.1-1.0
Locomotion in novel chamber1.72.04.00.9-1.51.8-2.00.4
Locomotion in novel chamber post-restriction2.73.24.41.9-2.11.9-2.0-0.7
Fecal boli incidents, locomotor time 11.51.72.31.3-1.51.5-1.5-0.2
Change in fecal boli incidents, locomotor task1.11.01.4-1.21.0-1.11.10.5
Time >=10cm from walls, locomotor time 12.32.33.11.6-1.81.7-1.7-0.5
Bouts of movement, locomotor time 10.20.30.40.5-0.50.7-0.7-0.1
Total resting periods, locomotor time 10.40.50.80.5-0.70.9-0.90.4
Rest time, locomotor task time 10.20.30.80.2-0.90.4-0.40.4
Distance moved, locomotor task time 10.40.51.1-0.11.0-0.70.6-0.7
Vertical activity count, locomotor time 10.20.20.60.40.5-0.30.3-0.8
Time >=10cm from walls, locomotor time 21.11.21.91.4-1.10.8-0.8-1.3
Bouts of movement, locomotor time 20.40.51.2-0.00.8-0.40.4-1.1
Total resting periods, locomotor time 20.50.51.0-0.41.0-0.70.7-0.8
Rest time, locomotor task time 22.22.53.8-2.01.2-1.51.61.6
Distance moved, locomotor task time 21.92.24.12.0-1.01.2-1.2-1.8
Vertical activity count, locomotor time 20.60.61.81.1-0.20.2-0.2-1.3
Light reinforcement 12.64.75.9-2.42.3-1.92.02.2
Light reinforcement 20.30.41.7-0.50.20.2-0.01.3
Bone: marrow area0.61.35.01.1-0.0-0.00.1-2.2
Bone: maximum diameter1.12.05.51.6-1.00.6-0.7-2.3
Bone: maximum force0.10.10.50.2-0.5-0.1-0.0-0.7
Bone: maximum moment0.20.30.80.4-0.70.1-0.2-0.9
Mean time between licks in bursts2.53.613.02.1-0.40.3-0.3-3.6
Mean num. licks in bursts3.74.46.62.6-2.12.1-2.2-1.3
Cd content in liver1.21.32.2-1.11.5-1.21.2-0.1
Co content in liver0.91.13.91.2-0.30.2-0.2-2.0
Cu content in liver0.50.72.80.70.2-0.10.1-1.7
Fe content in liver0.10.10.1-0.20.2-0.40.4-0.0
K content in liver0.50.50.6-0.60.8-0.80.8-0.7
Mg content in liver0.20.20.70.4-0.10.1-0.1-0.8
Mn content in liver0.60.72.6-1.00.1-0.10.11.6
Na content in liver0.50.50.60.8-0.80.6-0.6-0.7
Rb content in liver0.30.40.90.9-0.30.5-0.5-0.8
Se content in liver1.92.34.3-2.11.2-1.41.41.4
Sr content in liver0.30.20.80.2-0.90.4-0.40.2
Zn content in liver3.74.16.22.5-1.71.8-1.8-2.2
Bone: minimum diameter0.81.44.60.20.7-0.91.0-2.2
Time in familiar zone, hab. session 10.10.10.2-0.10.4-0.40.4-0.1
Time in novel zone, hab. session 10.20.20.4-0.60.3-0.40.4-0.0
Total zone transitions, hab. session 10.30.40.70.2-0.80.7-0.70.5
Total locomotion distance, hab. session 11.82.54.1-1.42.0-1.81.8-0.3
Locomotion velocity, hab. session 11.11.52.7-1.11.6-1.41.4-0.3
Time in familiar zone, hab. session 20.90.91.91.4-0.60.7-0.7-1.1
Time in novel zone, hab. session 20.20.20.4-0.60.0-0.10.10.6
Total zone transitions, hab. session 21.72.23.01.5-1.61.7-1.7-0.1
Total locomotion distance, hab. session 20.81.01.7-0.31.3-1.11.1-1.0
Locomotion velocity, hab. session 21.11.52.5-0.51.6-1.31.3-1.0
Novel to familiar place preference ratio0.10.10.30.2-0.50.3-0.3-0.4
Novelty place preference0.10.10.30.2-0.60.3-0.3-0.4
Time in novel zone, NPP test0.30.30.60.4-0.80.5-0.5-0.5
Total zone transitions, NPP test0.40.60.90.6-0.91.0-1.00.2
Total locomotion distance, NPP test1.11.52.1-1.01.5-1.41.4-0.5
Locomotion velocity, NPP test1.52.13.0-1.31.7-1.71.7-0.2
Intraocular pressure0.50.71.20.6-0.91.1-1.00.4
Delta distance traveled before/after self-admin2.12.33.21.6-1.81.8-1.4-0.4
Delta ambulatory time before/after self-admin2.52.84.31.7-2.02.1-1.6-0.2
Parametrial fat weight1.73.34.9-1.62.1-2.22.2-0.2
Pavlov. Cond. lever latency0.81.01.6-1.30.8-0.90.91.2
Pavlov. Cond. magazine entry latency1.92.54.32.1-1.21.3-1.3-1.9
Pavlov. Cond. change in total contacts1.01.11.91.4-0.70.8-0.8-1.4
Pavlov. Cond. index score1.82.33.92.0-1.01.2-1.2-1.8
Pavlov. Cond. latency score1.82.33.82.0-1.11.2-1.2-1.8
Pavlov. Cond. lever contacts0.80.92.21.2-0.50.6-0.6-1.5
Pavlov. Cond. magazine entry number2.53.25.2-2.31.5-1.51.51.9
Pavlov. Cond. intertrial magazine entries0.70.81.3-1.10.9-0.70.71.1
Pavlov. Cond. lever-magazine prob. diff.1.51.83.31.8-0.91.1-1.1-1.6
Pavlov. Cond. response bias0.80.92.01.2-0.60.6-0.6-1.4
Pavlov. Cond. lever latency12.817.228.3-5.33.7-3.63.64.3
Pavlov. Cond. magazine entry latency3.74.36.82.6-2.12.0-2.1-1.3
Pavlov. Cond. change in total contacts10.414.323.34.8-3.53.5-3.5-3.4
Pavlov. Cond. index score10.413.322.24.7-3.33.2-3.3-3.5
Pavlov. Cond. latency score9.511.819.54.4-3.23.1-3.1-3.2
Pavlov. Cond. lever contacts13.117.829.95.5-3.73.7-3.7-4.3
Pavlov. Cond. magazine entry number6.57.912.4-3.52.8-2.82.81.9
Pavlov. Cond. intertrial magazine entries0.81.01.4-0.31.1-1.11.1-1.2
Pavlov. Cond. lever-magazine prob. diff.9.512.120.44.5-3.13.0-3.1-3.5
Pavlov. Cond. response bias13.618.530.95.6-3.93.8-3.9-4.1
Time in closed arm before self-admin4.65.27.72.0-2.72.7-2.80.5
Time in closed arm after self-admin0.50.51.9-0.7-0.1-0.2-0.11.4
Time in open arm before self-admin4.85.27.3-2.72.5-2.32.21.4
Time in open arm after self-admin0.50.51.40.10.7-0.50.6-1.2
Bone: periosteal estimation0.71.55.71.2-0.60.1-0.1-2.4
Bone: periosteal perimeter0.81.34.21.3-0.70.4-0.4-2.0
Bone: post-yield work0.20.20.40.5-0.60.5-0.4-0.4
Progressive ratio test 1 active lever presses0.00.00.1-0.10.1-0.10.30.2
Progressive ratio test 1 breakpoint0.10.10.2-0.10.2-0.30.40.0
Progressive ratio test 1 inactive lever presses0.20.30.70.8-0.50.10.1-0.6
Progressive ratio test 2 active lever presses0.40.50.90.9-0.50.4-0.5-0.9
Progressive ratio test 2 breakpoint0.40.51.00.9-0.40.4-0.5-1.0
Progressive ratio test 2 inactive lever presses0.91.01.61.2-1.31.0-0.9-0.3
Incentive Sensitization - Responses1.11.12.21.3-0.50.6-0.9-1.5
Incentive Sensitization - Breakpoint1.11.11.71.3-0.60.8-1.0-1.3
Sum of active levers in priming session hrs 5-60.20.20.5-0.4-0.10.4-0.30.7
Progressive ratio0.20.20.30.1-0.50.5-0.60.3
Food seeking constrained by brief footshock0.40.62.30.70.10.1-0.2-1.5
Seeking ratio, punishment vs. effort0.60.72.70.50.5-0.50.5-1.6
Retroperitoneal fat weight6.220.329.3-3.85.2-5.35.4-1.3
Reaction time number correct1.01.42.20.5-1.51.3-1.50.8
Reaction time mean minus median0.20.30.80.90.00.3-0.2-0.8
Reaction time mean minus median AUC0.60.81.81.3-0.80.9-0.9-0.5
Reaction time num false alarms2.23.04.1-2.01.9-1.91.70.7
Reaction time num false alarms AUC1.01.42.1-1.41.2-1.31.10.6
Reaction time trials correct on left1.01.42.20.5-1.51.3-1.50.8
Reaction time trials on left1.01.42.20.5-1.51.3-1.50.8
Reaction time mean1.11.62.8-1.21.7-1.31.40.4
Reaction time mean AUC1.31.72.7-1.31.6-1.21.40.7
Median of all reaction times1.52.13.1-1.61.8-1.41.50.8
Reaction time omissions0.50.71.1-0.91.1-0.80.90.3
Reaction time false alarm rate2.02.73.8-1.71.9-1.91.80.3
Reaction time premature initiation rate1.01.45.10.90.5-0.60.6-2.3
Reaction time premature initiations0.60.92.41.2-0.50.3-0.4-1.6
Std. dev. reaction times0.50.71.5-0.01.2-0.80.8-0.9
Reaction time trials completed1.01.42.20.5-1.51.3-1.50.8
Reaction time trials AUC0.71.11.80.4-1.31.1-1.30.7
Run reversals in cocaine runway, females4.34.16.3-1.02.3-2.42.5-1.5
Run reversals in cocaine runway, males0.10.10.2-0.2-0.0-0.20.20.5
Latency to leave start box in cocaine runway3.53.85.5-1.92.1-2.32.30.4
Latency to leave start box in cocaine runway, F3.84.26.3-1.82.3-2.52.5-0.2
Latency to leave start box in cocaine runway, M0.20.20.6-0.4-0.0-0.10.00.8
Std. dev. time between licks in bursts1.31.66.70.60.4-0.50.7-2.6
Total sessions with >9 infusions2.93.25.22.3-2.01.8-1.6-1.0
Short access day 1 total inactive lever presses0.10.10.20.1-0.1-0.40.50.2
Short access day 10 total inactive lever presses0.10.10.1-0.30.1-0.2-0.10.4
Short access day 1 total infusions1.92.03.92.0-1.21.1-1.1-1.4
Short access day 10 total infusions0.80.91.91.4-0.60.5-0.5-1.4
Short access total infusions0.80.92.01.4-0.80.5-0.4-1.2
Short access day 1 locomotion2.83.04.11.9-2.02.0-1.9-0.2
Short access day 10 total locomotion0.20.20.30.4-0.10.4-0.5-0.6
Short access total locomotion0.20.20.30.5-0.40.6-0.4-0.2
One hour access (0.3 mA shock)1.61.93.11.8-1.21.2-1.2-1.4
Compulsive drug intake0.30.30.6-0.1-0.50.4-0.70.7
One hour access (shock baseline)1.21.42.31.5-0.81.0-0.8-1.5
Social response proportion0.70.81.4-0.61.0-1.21.0-0.2
Social responses1.31.62.6-0.71.6-1.61.6-0.4
Social time1.72.34.3-1.71.1-1.21.22.1
Soleus weight1.03.03.9-0.91.8-2.02.0-1.8
Bone: stiffness0.40.71.2-0.70.6-1.11.0-0.7
Tibialis anterior weight0.10.20.70.10.3-0.50.4-0.8
Time to tail flick, vehicle, before self-admin0.10.10.2-0.2-0.20.4-0.20.3
Time to tail flick, vehicle, after self-admin3.03.24.82.2-2.11.8-1.6-0.7
Time to tail flick, test, before self-admin0.20.20.90.40.00.20.1-0.9
Time to tail flick, test, after self-admin0.70.82.50.20.6-0.70.7-1.6
Delta time to tail flick, vehicle, before/after SA1.81.83.61.9-1.61.2-1.0-0.7
Delta time to tail flick, test, before/after SA0.40.40.8-0.50.6-0.90.60.0
Tibia length2.15.97.82.7-2.62.8-2.8-0.4
Ambulatory time before self-admin1.01.01.8-1.31.0-0.90.71.1
Ambulatory time after self-admin1.11.21.90.2-1.21.3-1.01.4
Bone: tissue strength0.80.81.7-0.0-0.90.8-0.81.3
Total heroin consumption0.50.61.00.6-0.91.0-0.90.0
Bone: trabecular number0.40.62.1-1.00.1-0.00.11.4
Bone: trabecular spacing0.91.11.91.1-1.40.8-0.9-1.0
Bone: trabecular thickness0.30.40.6-0.50.8-0.70.60.4
Bone: trabecular tissue density2.73.85.7-1.72.3-2.42.2-0.5
Water consumed over 24 hours0.30.40.8-0.80.2-0.30.40.9
Number of responses in last shaping day0.10.10.50.30.1-0.20.1-0.7