Hub : Genes

LOC103690119

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC103690119 0.53 0.18 0.0e+00 0.41 0.42 0.4 0.42 2.5e-19 1.7e-19 9.4e-19 1.1e-19
2 BLA gene expression LOC103690119 0.66 0.18 0.0e+00 0.44 0.5 0.5 0.52 5.7e-26 3.1e-30 9.3e-31 1.4e-31
3 PL gene expression LOC103690119 0.58 0.16 0.0e+00 0.58 0.6 0.6 0.61 7.3e-78 5.3e-82 1.0e-82 7.3e-84
4 NAcc gene expression LOC103690119 0.52 0.15 0.0e+00 0.51 0.53 0.53 0.53 1.1e-68 6.6e-72 4.9e-73 4.8e-73
5 LHb gene expression LOC103690119 0.57 0.18 9.6e-12 0.27 0.37 0.39 0.28 3.7e-07 1.0e-09 3.0e-10 2.1e-07
6 Liver gene expression LOC103690119 0.74 0.19 0.0e+00 0.38 0.39 0.4 0.4 5.2e-45 1.2e-45 1.6e-47 5.5e-48
7 Brain gene expression LOC103690119 0.69 0.16 0.0e+00 0.47 0.47 0.49 0.49 1.7e-48 7.3e-49 6.1e-52 3.3e-51
8 IL gene expression LOC103690119 0.64 0.17 3.2e-12 0.25 0.28 0.26 0.27 1.1e-06 1.5e-07 6.2e-07 4.1e-07
9 Adipose gene expression LOC103690119 0.86 0.1 0.0e+00 0.34 0.4 0.4 0.41 8.6e-39 5.9e-47 5.6e-48 5.3e-49
10 RMTg gene expression LOC103690119 0.31 0.17 3.1e-05 0.07 0.14 0.07 0.08 5.9e-03 1.8e-04 6.6e-03 3.3e-03
11 OFC gene expression LOC103690119 0.59 0.18 9.7e-12 0.29 0.38 0.36 0.33 1.6e-07 6.1e-10 2.3e-09 1.1e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.81.33.4-0.6-0.6-0.6-0.70.9-0.70.9-1.4-1.6-1.6-1.9
Area under the delay curve2.02.12.6-1.4-1.6-1.6-1.61.5-1.11.6-1.5-1.2-1.5-1.4
BMI with tail5.317.021.0-4.6-4.5-4.5-4.54.4-4.34.2-3.8-3.6-3.6-3.2
BMI without tail1.32.73.8-1.9-1.9-1.9-1.91.8-1.71.7-1.4-1.2-1.3-1.0
Body weight1.04.15.8-2.3-2.2-2.1-2.12.1-2.42.1-1.8-1.9-1.7-1.4
Weight adjusted by age0.10.10.4-0.3-0.4-0.4-0.30.20.40.2-0.10.6-0.00.1
Bone surface1.01.75.5-0.4-0.3-0.3-0.50.8-0.70.9-1.6-2.1-1.9-2.3
Bone volume1.01.75.4-0.4-0.3-0.3-0.50.8-0.70.9-1.6-2.1-1.9-2.3
Breakpoint value in progressive ratio session4.95.46.52.52.42.42.4-2.51.9-2.52.41.82.32.2
Number of licking bursts0.10.10.5-0.1-0.1-0.00.0-0.1-0.1-0.30.50.40.60.7
Context. condit. distance diff. score0.30.30.4-0.7-0.6-0.6-0.60.6-0.70.7-0.5-0.5-0.5-0.4
Locomotion velocity, session 10.10.20.30.50.60.50.5-0.4-0.00.00.0-0.6-0.1-0.3
Locomotion distance, session 10.20.31.10.0-0.0-0.1-0.10.30.30.6-0.7-0.4-0.8-1.0
Locomotion velocity, session 21.21.42.81.61.71.61.5-1.41.1-1.10.70.20.50.2
Locomotion distance, session 20.40.51.21.11.01.00.9-0.81.1-0.40.20.2-0.0-0.4
Locomotion velocity, session 35.66.58.02.82.72.72.7-2.72.7-2.62.42.42.32.0
Locomotion distance, session 30.10.10.40.30.20.20.2-0.20.6-0.20.30.60.30.3
Stereotopy head waving bouts, day 33.54.27.52.42.22.22.1-2.12.7-1.91.62.11.51.2
Stereotopy head waving duration, day 34.25.07.02.62.52.42.4-2.32.6-2.22.02.11.81.5
Locomotion velocity, session 70.40.40.70.80.90.80.8-0.70.2-0.70.5-0.10.50.3
Locomotion distance, session 70.10.10.3-0.1-0.00.00.0-0.1-0.4-0.20.3-0.00.40.5
Stereotopy head waving bouts, day 70.30.41.1-0.1-0.3-0.3-0.40.50.70.6-0.80.1-0.9-1.0
Stereotopy head waving duration, day 70.20.20.80.10.0-0.0-0.10.20.60.3-0.6-0.1-0.7-0.9
Locomotion velocity, session 80.20.20.90.30.20.20.10.10.60.3-0.5-0.3-0.7-0.9
Locomotion distance, session 80.00.00.10.20.20.20.1-0.10.40.1-0.10.1-0.2-0.2
Degree of sensitization distance0.60.61.8-0.8-0.7-0.6-0.60.7-1.30.7-0.6-1.2-0.6-0.5
Degree of sensitization stereotypy2.42.63.4-1.5-1.6-1.7-1.71.7-0.81.8-1.8-1.1-1.8-1.8
Conditioned locomotion0.60.71.7-1.1-1.1-1.0-0.90.8-1.30.6-0.4-0.5-0.20.1
Cocaine response after cond. corrected2.42.74.3-2.1-2.0-1.9-1.91.8-1.91.8-1.2-1.1-1.0-0.7
Cocaine response after cond. not corrected2.42.64.3-2.1-2.0-1.9-1.91.8-1.81.8-1.2-0.9-1.0-0.6
Cocaine response before conditioning0.30.41.00.70.70.70.7-0.61.0-0.60.40.70.30.2
Saline control response0.00.00.1-0.1-0.1-0.1-0.10.1-0.20.00.1-0.00.10.2
Bone: connectivity density0.91.43.0-0.8-0.8-0.9-0.91.1-0.71.1-1.4-1.4-1.6-1.7
Bone: cortical apparent density1.11.51.9-1.3-1.4-1.4-1.31.3-1.11.3-1.1-0.9-1.1-1.0
Bone: cortical area1.42.13.2-1.3-1.2-1.3-1.31.5-1.21.4-1.6-1.6-1.7-1.8
Bone: cortical porosity0.20.20.40.60.60.60.6-0.50.1-0.40.3-0.20.20.1
Bone: cortical porosity0.20.20.7-0.2-0.1-0.2-0.20.3-0.50.4-0.5-0.9-0.6-0.7
Bone: cortical thickness1.52.42.9-1.6-1.6-1.6-1.61.7-1.31.6-1.6-1.4-1.6-1.6
Bone: cortical thickness0.10.20.50.30.30.30.3-0.4-0.1-0.40.50.20.60.7
Bone: cortical tissue density0.81.01.4-1.1-1.2-1.2-1.11.1-0.91.1-0.9-0.7-0.9-0.8
Condit. Reinf. active minus inactive responses3.43.85.02.22.22.12.1-2.12.1-1.91.81.71.61.5
Condit. Reinf. active-inactive response ratio2.32.52.91.71.71.71.7-1.71.3-1.61.61.31.61.6
Condit. Reinf. active responses2.22.74.72.01.91.91.8-1.72.2-1.51.21.41.10.8
Condit. Reinf. inactive responses0.20.30.90.70.70.60.6-0.40.9-0.30.10.3-0.1-0.3
Incentive salience index mean1.11.42.31.51.41.41.4-1.31.4-1.00.90.80.70.5
Condit. Reinf. lever presses0.40.61.8-0.2-0.3-0.3-0.40.6-0.20.8-1.0-0.9-1.1-1.3
Condit. Reinf. active minus inactive responses3.24.04.52.01.92.02.0-2.01.9-2.12.02.02.02.0
Condit. Reinf. active-inactive response ratio1.11.12.10.70.70.70.8-0.90.9-1.01.21.41.31.4
Condit. Reinf. active responses2.23.13.71.91.91.91.9-1.91.6-1.91.71.41.61.5
Condit. Reinf. inactive responses0.60.71.31.11.11.11.1-1.00.6-1.00.70.20.60.4
Condit. Reinf. lever presses2.83.84.72.02.02.02.0-2.11.5-2.22.01.62.01.9
Condit. Reinf. lever reinforcers received2.02.83.51.71.81.81.8-1.81.4-1.91.71.31.71.6
Conditioned reinforcement - actives1.71.72.61.51.61.61.6-1.50.9-1.31.20.61.11.0
Conditioned reinforcement - inactives0.10.20.4-0.5-0.6-0.6-0.50.30.00.3-0.10.50.00.2
Conditioned locomotion7.28.610.73.33.23.23.2-3.22.9-3.02.82.42.62.4
Patch foraging indifference point 0 sec0.60.94.4-0.6-0.5-0.5-0.50.4-2.10.6-0.5-1.9-0.5-0.4
Patch foraging indifference point AUC0.70.91.21.01.11.11.1-0.90.6-0.91.00.51.00.9
Delay disc. indifference point, 0s delay8.89.611.4-3.0-3.1-3.1-3.23.2-2.23.4-3.4-2.6-3.4-3.3
Delay disc. indifference point, 16s delay0.10.10.2-0.3-0.4-0.4-0.40.30.10.4-0.4-0.0-0.4-0.4
Delay disc. indifference point, 2s delay5.76.37.5-2.5-2.7-2.7-2.72.7-1.52.7-2.7-1.7-2.7-2.5
Delay disc. indifference point, 24s delay0.60.51.1-0.7-0.7-0.7-0.70.7-1.00.7-0.6-1.0-0.6-0.5
Delay disc. indifference point, 4s delay1.51.62.4-1.1-1.2-1.2-1.31.3-0.51.4-1.5-0.9-1.5-1.5
Delay disc. indifference point, 8s delay0.40.50.7-0.8-0.8-0.9-0.80.7-0.80.7-0.5-0.5-0.4-0.3
Indifference point function ln k0.10.20.3-0.5-0.5-0.5-0.50.5-0.20.4-0.4-0.0-0.4-0.3
Indifference point function log k0.10.20.3-0.5-0.5-0.5-0.50.5-0.20.4-0.4-0.0-0.4-0.3
Patch foraging total patch changes 0 sec0.50.84.3-0.6-0.4-0.4-0.40.3-2.10.4-0.4-1.8-0.3-0.3
Patch foraging total patch changes 12 sec0.30.42.5-0.5-0.4-0.4-0.40.2-1.60.2-0.0-1.10.10.2
Patch foraging total patch changes 18 sec0.60.71.00.91.01.01.0-1.0-0.3-0.90.9-0.30.90.8
Patch foraging total patch changes 24 sec0.10.10.50.10.10.10.1-0.2-0.7-0.20.1-0.70.10.1
Patch foraging total patch changes 6 sec0.40.52.10.30.60.60.5-0.5-1.5-0.40.5-1.30.50.5
Patch foraging time to switch 0 sec1.92.93.7-1.6-1.8-1.8-1.81.7-1.01.8-1.9-1.2-1.9-1.9
Patch foraging water rate 0 sec0.30.61.50.40.60.60.6-0.7-0.1-0.71.00.41.11.2
Patch foraging water rate 12 sec0.30.40.9-0.9-0.9-0.8-0.80.7-0.70.6-0.30.0-0.10.2
Patch foraging water rate 18 sec1.41.84.30.90.80.91.0-1.20.7-1.41.71.61.82.1
Patch foraging water rate 24 sec0.60.93.30.10.20.20.4-0.6-0.0-0.71.21.21.51.8
Patch foraging water rate 6 sec1.62.45.31.11.01.01.1-1.31.8-1.41.72.31.71.9
Seeking ratio, delayed vs. immediate footshock3.23.75.42.32.32.32.2-2.11.6-2.11.71.01.61.3
Distance traveled before self-admin0.40.40.9-0.3-0.6-0.6-0.60.51.00.5-0.60.7-0.7-0.7
Distance traveled after self-admin0.60.61.00.91.01.01.0-0.90.3-0.90.80.10.70.6
Extensor digitorum longus weight2.911.415.9-4.0-4.0-4.0-3.83.6-3.93.3-2.8-2.7-2.4-1.9
Bone: elastic displacement0.20.20.40.50.60.60.6-0.50.6-0.50.40.40.40.3
Bone: elastic work0.40.50.6-0.7-0.6-0.6-0.60.7-0.70.7-0.8-0.8-0.8-0.8
Bone: endosteal estimation0.61.32.7-1.0-0.8-0.8-0.91.0-1.51.0-1.1-1.7-1.1-1.1
Bone: endosteal perimeter0.00.10.30.30.30.30.3-0.10.4-0.1-0.2-0.2-0.4-0.5
Epididymis fat weight0.30.71.00.70.80.90.9-0.80.5-0.80.90.71.01.0
Delta time in closed arm before/after self-admin0.30.21.0-0.2-0.1-0.1-0.0-0.10.0-0.30.60.80.71.0
Delta time in open arm before/after self-admin1.81.72.2-1.3-1.4-1.4-1.41.3-1.51.4-1.2-1.4-1.1-1.1
Diff in mean of infusions in LGA sessions1.51.72.81.41.21.21.2-1.21.7-1.41.21.51.21.0
Delay discount exponential model param1.81.92.31.41.51.51.5-1.41.1-1.51.41.11.41.3
Extinction: sum of active levers before priming2.42.44.31.41.21.21.3-1.41.9-1.51.62.11.61.6
Active lever presses in extinction session 61.91.82.41.51.51.51.6-1.50.9-1.51.40.61.31.1
Bone: final force2.13.44.9-1.7-1.6-1.6-1.71.8-2.01.7-1.9-2.2-1.9-1.9
Bone: final moment1.82.94.7-1.5-1.5-1.5-1.51.6-2.01.6-1.7-2.2-1.8-1.8
Food consumed during 24 hour testing period0.40.50.6-0.8-0.8-0.8-0.80.7-0.70.7-0.6-0.6-0.6-0.5
Glucose0.91.42.5-1.3-1.2-1.2-1.21.2-1.61.1-1.0-1.2-0.9-0.7
Heart weight0.50.71.10.70.80.80.9-0.90.4-0.91.00.61.01.1
Delay discount hyperbolic model param2.62.83.31.71.81.81.8-1.71.3-1.81.71.31.71.6
Intermittent access intake day 1-15 change6.26.17.62.52.72.82.7-2.71.7-2.72.61.72.52.4
Intermittent access intake escalation7.77.59.02.62.82.92.9-2.91.7-3.03.02.03.03.0
Intermittent access intake escalation 28.98.810.42.93.23.23.2-3.21.8-3.23.22.03.23.1
Intermitt. access day 1 inactive lever presses1.21.32.41.00.90.91.0-1.01.4-1.11.11.51.21.2
Intermitt. access day 15 inactive lever presses1.11.22.91.10.80.70.8-0.91.6-0.80.91.70.90.9
Intermitt. access escalation Index1.10.91.9-0.8-0.8-0.8-0.91.0-0.41.0-1.2-0.9-1.3-1.4
Intermittent access day 1 total infusions0.20.20.2-0.3-0.4-0.4-0.40.3-0.50.5-0.4-0.5-0.4-0.4
Intermittent access day 15 total infusions1.82.12.81.51.51.51.5-1.70.7-1.51.60.91.61.6
Intermittent access terminal intake (last 3 days)0.70.81.31.01.11.01.0-1.10.4-0.90.90.30.90.8
Intermittent access total infusions0.20.20.40.40.40.40.4-0.60.0-0.40.50.20.50.5
Intermittent access day 1 locomotion0.30.30.40.50.50.50.5-0.60.1-0.50.60.30.60.6
Intermittent access day 15 total locomotion3.43.74.11.92.02.02.0-2.01.8-2.01.91.81.91.8
Intermittent access total locomotion0.81.01.11.01.01.01.0-1.10.9-1.01.00.90.90.9
Intermittent access standard deviation3.13.34.41.92.02.02.0-2.11.0-1.91.91.11.91.8
Left kidney weight0.10.31.6-0.1-0.0-0.1-0.10.2-0.90.3-0.5-1.3-0.6-0.7
Right kidney weight0.82.33.51.81.91.81.8-1.71.0-1.61.40.61.31.1
Cocaine induced anxiety0.20.30.60.70.70.70.6-0.60.7-0.50.10.1-0.0-0.2
Post-drug Anxiety0.20.20.90.30.40.30.3-0.1-0.2-0.0-0.4-0.9-0.5-0.7
Baseline Anxiety0.10.10.20.20.20.20.2-0.20.2-0.30.30.40.40.4
Tail length3.410.311.43.33.33.33.3-3.43.3-3.33.13.13.02.8
Length with tail1.34.96.62.52.62.62.5-2.51.8-2.32.11.52.01.8
Length without tail0.10.20.6-0.1-0.0-0.0-0.10.2-0.50.3-0.4-0.8-0.5-0.6
Times rat made contact with spout0.00.00.1-0.2-0.2-0.1-0.10.1-0.30.00.10.10.20.3
Lifetime Intake0.00.00.20.10.10.10.1-0.3-0.4-0.00.1-0.40.10.1
Liver weight, left1.32.03.0-1.7-1.6-1.5-1.51.6-1.41.5-1.3-0.9-1.2-1.0
Liver weight, right1.32.22.7-1.7-1.6-1.6-1.61.6-1.11.6-1.5-0.9-1.4-1.3
Locomotor activity1.92.94.42.12.12.12.0-1.82.1-1.71.31.31.10.8
Locomotor testing distance1.11.93.01.61.71.71.7-1.51.4-1.31.10.91.00.7
Locomotor testing rearing0.00.00.10.10.20.20.2-0.20.0-0.20.20.10.30.3
Locomotion in novel chamber0.50.60.80.70.90.90.9-0.8-0.3-0.80.8-0.20.80.8
Locomotion in novel chamber post-restriction0.91.13.51.00.91.00.9-0.91.9-0.90.71.50.60.5
Fecal boli incidents, locomotor time 10.60.71.4-1.0-1.2-1.2-1.11.0-0.60.8-0.6-0.1-0.5-0.2
Change in fecal boli incidents, locomotor task0.10.10.40.30.30.30.2-0.00.50.1-0.4-0.1-0.5-0.7
Time >=10cm from walls, locomotor time 10.90.91.4-0.8-0.8-0.8-0.80.8-0.91.0-1.1-1.2-1.1-1.2
Bouts of movement, locomotor time 10.20.20.30.50.40.40.4-0.40.6-0.30.40.60.40.4
Total resting periods, locomotor time 10.20.30.80.50.40.40.4-0.40.9-0.30.40.80.30.3
Rest time, locomotor task time 10.10.10.40.30.20.20.2-0.30.6-0.20.00.4-0.0-0.1
Distance moved, locomotor task time 11.01.12.1-0.9-0.8-0.8-0.81.0-1.21.0-1.1-1.5-1.2-1.2
Vertical activity count, locomotor time 10.10.10.4-0.1-0.1-0.1-0.10.2-0.60.10.1-0.40.10.1
Time >=10cm from walls, locomotor time 20.60.61.3-1.0-0.9-0.9-0.90.8-1.20.7-0.6-0.8-0.5-0.3
Bouts of movement, locomotor time 20.10.10.30.40.40.40.3-0.2-0.1-0.1-0.0-0.5-0.1-0.3
Total resting periods, locomotor time 20.10.10.40.30.30.30.2-0.1-0.10.1-0.2-0.6-0.3-0.4
Rest time, locomotor task time 20.20.20.40.50.60.60.5-0.4-0.3-0.30.1-0.70.1-0.1
Distance moved, locomotor task time 20.30.30.7-0.8-0.8-0.8-0.80.6-0.10.6-0.40.3-0.3-0.1
Vertical activity count, locomotor time 20.20.20.5-0.7-0.7-0.7-0.60.5-0.60.4-0.10.00.00.2
Light reinforcement 14.98.912.53.33.13.13.1-3.13.5-2.92.72.92.52.2
Light reinforcement 21.52.12.81.71.61.51.5-1.61.5-1.41.31.31.21.1
Bone: marrow area0.61.32.6-1.0-0.9-0.9-0.91.0-1.51.0-1.1-1.6-1.1-1.1
Bone: maximum diameter0.10.20.40.60.60.60.5-0.30.4-0.4-0.1-0.3-0.3-0.5
Bone: maximum force2.13.65.0-1.8-1.8-1.8-1.81.9-2.11.8-1.9-2.2-1.9-1.9
Bone: maximum moment1.93.34.9-1.7-1.6-1.6-1.71.7-2.11.7-1.8-2.2-1.8-1.8
Mean time between licks in bursts4.25.96.42.52.52.52.5-2.52.5-2.52.42.42.32.2
Mean num. licks in bursts0.00.00.1-0.00.00.0-0.00.1-0.00.2-0.2-0.2-0.3-0.3
Cd content in liver0.20.20.3-0.5-0.5-0.5-0.50.5-0.60.4-0.5-0.6-0.5-0.4
Co content in liver1.01.21.61.01.21.31.3-1.00.9-1.11.11.01.11.1
Cu content in liver0.40.51.0-0.5-0.4-0.5-0.50.6-0.60.7-0.9-1.0-0.9-1.0
Fe content in liver0.10.10.30.20.20.20.2-0.30.1-0.40.40.40.50.6
K content in liver0.20.20.6-0.1-0.2-0.2-0.20.3-0.10.4-0.6-0.5-0.7-0.8
Mg content in liver0.30.31.0-0.2-0.3-0.3-0.40.4-0.30.5-0.7-0.8-0.8-1.0
Mn content in liver0.30.31.20.50.50.50.4-0.10.30.2-0.5-0.7-0.8-1.1
Na content in liver1.51.62.0-1.2-1.4-1.4-1.41.2-1.11.2-1.3-1.2-1.3-1.3
Rb content in liver1.01.32.3-1.0-0.8-0.8-0.91.1-1.01.1-1.4-1.4-1.4-1.5
Se content in liver0.10.10.20.40.40.30.3-0.30.4-0.20.30.20.20.2
Sr content in liver0.40.40.90.30.30.30.3-0.40.4-0.60.80.80.91.0
Zn content in liver4.34.75.91.92.02.02.1-2.22.0-2.22.32.42.42.4
Bone: minimum diameter0.20.40.9-0.4-0.4-0.4-0.50.6-0.50.5-0.8-0.9-0.8-0.9
Time in familiar zone, hab. session 12.92.74.31.71.61.61.6-1.62.1-1.61.52.01.51.4
Time in novel zone, hab. session 12.32.34.1-1.3-1.2-1.2-1.31.4-1.81.4-1.5-2.0-1.6-1.6
Total zone transitions, hab. session 10.30.40.70.80.80.80.7-0.60.8-0.30.10.1-0.0-0.2
Total locomotion distance, hab. session 10.30.41.20.80.80.70.6-0.41.1-0.1-0.30.0-0.5-0.8
Locomotion velocity, hab. session 10.50.71.91.21.11.11.0-0.81.4-0.50.20.40.0-0.3
Time in familiar zone, hab. session 27.47.78.52.82.82.82.8-2.92.6-2.92.82.62.72.7
Time in novel zone, hab. session 26.26.26.6-2.5-2.4-2.4-2.52.6-2.52.5-2.5-2.6-2.5-2.5
Total zone transitions, hab. session 21.01.32.5-0.7-0.7-0.7-0.81.0-0.81.3-1.3-1.4-1.4-1.6
Total locomotion distance, hab. session 20.30.40.80.80.90.90.8-0.70.7-0.30.20.00.1-0.1
Locomotion velocity, hab. session 20.20.30.60.70.80.70.7-0.50.6-0.10.0-0.2-0.2-0.4
Novel to familiar place preference ratio5.65.86.4-2.3-2.3-2.3-2.32.4-2.22.5-2.5-2.5-2.5-2.5
Novelty place preference3.73.74.4-1.8-1.8-1.8-1.81.9-1.82.0-2.1-2.1-2.1-2.1
Time in novel zone, NPP test3.94.14.8-1.9-1.9-1.9-1.92.0-2.02.0-2.1-2.2-2.1-2.1
Total zone transitions, NPP test0.20.20.5-0.2-0.2-0.2-0.30.3-0.30.7-0.5-0.7-0.6-0.7
Total locomotion distance, NPP test0.30.41.0-0.3-0.3-0.3-0.40.5-0.10.8-0.8-0.6-0.9-1.0
Locomotion velocity, NPP test0.10.20.60.0-0.0-0.0-0.10.20.20.5-0.5-0.3-0.6-0.8
Intraocular pressure0.60.91.70.70.60.70.7-0.90.8-0.91.01.31.11.2
Delta distance traveled before/after self-admin1.11.21.81.01.31.31.3-1.2-0.4-1.21.1-0.41.11.0
Delta ambulatory time before/after self-admin0.91.01.71.01.31.31.3-1.1-0.6-1.00.9-0.70.80.7
Parametrial fat weight0.61.11.50.91.11.21.2-1.10.8-1.21.10.91.01.0
Pavlov. Cond. lever latency0.30.31.00.30.30.30.4-0.50.1-0.70.80.60.91.0
Pavlov. Cond. magazine entry latency2.43.13.71.91.91.91.9-1.91.5-1.71.71.31.71.6
Pavlov. Cond. change in total contacts0.00.00.10.20.30.30.3-0.2-0.0-0.10.2-0.10.10.1
Pavlov. Cond. index score0.10.10.30.50.50.50.5-0.30.5-0.10.10.10.0-0.1
Pavlov. Cond. latency score0.10.10.20.40.40.40.3-0.20.50.0-0.1-0.1-0.3-0.4
Pavlov. Cond. lever contacts0.30.30.9-0.1-0.1-0.1-0.20.3-0.30.5-0.7-0.9-0.8-1.0
Pavlov. Cond. magazine entry number0.40.50.7-0.8-0.9-0.9-0.80.8-0.60.7-0.7-0.5-0.7-0.6
Pavlov. Cond. intertrial magazine entries0.40.51.00.60.50.50.5-0.60.7-0.70.81.00.80.9
Pavlov. Cond. lever-magazine prob. diff.0.30.30.60.80.80.80.7-0.60.7-0.40.40.30.30.1
Pavlov. Cond. response bias0.70.91.21.11.11.11.1-1.00.8-0.90.90.60.80.7
Pavlov. Cond. lever latency0.70.91.2-1.1-1.1-1.1-1.11.1-0.81.1-0.9-0.5-0.8-0.7
Pavlov. Cond. magazine entry latency0.40.41.50.70.60.60.6-0.51.2-0.60.30.90.30.2
Pavlov. Cond. change in total contacts0.91.21.51.21.21.21.2-1.20.9-1.21.10.81.11.0
Pavlov. Cond. index score0.91.11.51.21.11.11.1-1.11.2-1.10.91.00.90.8
Pavlov. Cond. latency score0.60.81.11.01.01.01.0-0.91.1-0.90.70.80.60.5
Pavlov. Cond. lever contacts0.81.11.51.11.11.11.1-1.20.7-1.21.10.71.11.0
Pavlov. Cond. magazine entry number0.60.71.7-1.0-0.9-0.9-0.90.8-1.30.8-0.6-0.9-0.5-0.4
Pavlov. Cond. intertrial magazine entries0.20.20.5-0.6-0.6-0.6-0.50.5-0.70.4-0.2-0.3-0.10.0
Pavlov. Cond. lever-magazine prob. diff.0.81.01.41.11.11.11.1-1.01.2-1.00.80.90.70.6
Pavlov. Cond. response bias1.92.63.21.71.71.71.7-1.71.4-1.81.61.31.51.4
Time in closed arm before self-admin1.51.72.2-1.2-1.3-1.3-1.31.4-1.01.3-1.4-1.2-1.4-1.5
Time in closed arm after self-admin0.10.10.10.10.30.30.3-0.2-0.2-0.30.3-0.20.30.3
Time in open arm before self-admin1.61.72.21.31.41.51.5-1.41.2-1.31.31.11.21.2
Time in open arm after self-admin0.50.60.9-0.9-0.9-0.9-0.90.7-0.90.9-0.6-0.7-0.6-0.4
Bone: periosteal estimation1.22.54.6-1.4-1.2-1.2-1.31.5-1.81.4-1.7-2.2-1.8-1.8
Bone: periosteal perimeter0.20.41.2-0.2-0.2-0.2-0.30.4-0.20.4-0.8-0.8-0.9-1.1
Bone: post-yield work0.60.81.1-1.0-1.0-1.0-1.01.0-0.81.0-0.9-0.6-0.8-0.7
Progressive ratio test 1 active lever presses0.10.10.2-0.2-0.3-0.3-0.30.2-0.40.3-0.1-0.2-0.00.0
Progressive ratio test 1 breakpoint0.10.10.3-0.4-0.5-0.4-0.40.3-0.50.4-0.3-0.3-0.2-0.1
Progressive ratio test 1 inactive lever presses0.10.10.70.20.00.00.0-0.00.8-0.00.00.70.0-0.0
Progressive ratio test 2 active lever presses0.30.30.60.60.60.60.6-0.70.1-0.50.70.20.70.7
Progressive ratio test 2 breakpoint0.20.20.50.60.60.60.6-0.70.3-0.50.50.20.40.4
Progressive ratio test 2 inactive lever presses0.00.00.10.30.20.10.2-0.30.1-0.10.10.10.00.0
Incentive Sensitization - Responses0.60.60.80.80.70.70.8-0.80.8-0.80.80.90.80.8
Incentive Sensitization - Breakpoint0.60.60.80.80.80.80.8-0.80.9-0.80.70.80.70.7
Sum of active levers in priming session hrs 5-60.10.10.30.1-0.1-0.1-0.1-0.00.5-0.20.10.50.10.1
Progressive ratio0.10.10.6-0.3-0.3-0.3-0.30.3-0.80.3-0.0-0.50.00.1
Food seeking constrained by brief footshock0.20.20.60.40.40.40.4-0.40.8-0.40.40.70.30.3
Seeking ratio, punishment vs. effort0.20.21.30.30.30.30.3-0.31.1-0.40.10.90.10.0
Retroperitoneal fat weight0.41.33.7-1.4-1.1-1.1-1.01.1-1.91.1-0.7-1.3-0.6-0.3
Reaction time number correct0.20.20.6-0.8-0.6-0.5-0.50.4-0.80.3-0.0-0.20.10.3
Reaction time mean minus median0.50.71.01.01.01.01.0-0.90.8-0.80.70.60.60.5
Reaction time mean minus median AUC0.30.41.5-0.2-0.2-0.3-0.30.50.10.7-0.9-0.6-1.0-1.2
Reaction time num false alarms0.00.10.3-0.1-0.1-0.1-0.1-0.0-0.60.10.1-0.40.10.2
Reaction time num false alarms AUC0.00.10.4-0.1-0.1-0.1-0.1-0.1-0.60.10.2-0.20.30.4
Reaction time trials correct on left0.20.20.6-0.8-0.6-0.5-0.50.4-0.80.3-0.0-0.20.10.3
Reaction time trials on left0.20.30.6-0.8-0.6-0.6-0.50.5-0.80.4-0.1-0.20.00.2
Reaction time mean0.30.41.0-0.3-0.4-0.4-0.50.6-0.00.6-0.8-0.5-0.9-1.0
Reaction time mean AUC0.30.51.1-0.4-0.5-0.5-0.60.6-0.30.7-0.9-0.7-0.9-1.1
Median of all reaction times0.81.11.9-0.8-0.9-1.0-1.01.1-0.41.1-1.2-0.8-1.3-1.4
Reaction time omissions0.10.10.10.40.40.30.3-0.3-0.2-0.20.2-0.40.10.1
Reaction time false alarm rate0.00.00.20.0-0.0-0.1-0.10.0-0.40.2-0.1-0.4-0.2-0.2
Reaction time premature initiation rate1.82.44.01.51.31.31.4-1.51.8-1.41.62.01.61.6
Reaction time premature initiations1.52.13.51.21.11.21.2-1.31.3-1.31.71.91.81.9
Std. dev. reaction times0.10.10.20.40.40.40.4-0.20.2-0.0-0.0-0.2-0.1-0.2
Reaction time trials completed0.20.30.6-0.8-0.6-0.6-0.50.5-0.80.4-0.1-0.20.00.2
Reaction time trials AUC0.10.20.6-0.7-0.6-0.5-0.40.4-0.80.30.1-0.10.20.4
Run reversals in cocaine runway, females0.40.40.70.80.80.80.7-0.70.8-0.50.40.40.30.1
Run reversals in cocaine runway, males1.00.92.61.21.01.01.0-0.91.6-0.90.61.10.40.3
Latency to leave start box in cocaine runway0.40.41.90.40.60.60.5-0.4-0.9-0.3-0.0-1.4-0.2-0.4
Latency to leave start box in cocaine runway, F1.21.34.1-0.6-0.4-0.5-0.60.8-1.30.9-1.3-2.0-1.4-1.6
Latency to leave start box in cocaine runway, M3.33.24.21.71.81.81.9-2.00.7-1.92.01.02.02.0
Std. dev. time between licks in bursts0.20.30.50.70.70.70.7-0.50.7-0.50.20.20.0-0.2
Total sessions with >9 infusions0.20.20.6-0.2-0.2-0.2-0.30.30.20.4-0.6-0.2-0.7-0.8
Short access day 1 total inactive lever presses0.00.00.10.30.20.20.2-0.30.2-0.30.20.20.20.2
Short access day 10 total inactive lever presses0.40.41.10.50.40.40.5-0.50.8-0.60.71.10.70.8
Short access day 1 total infusions0.20.20.8-0.1-0.0-0.1-0.10.2-0.60.3-0.4-0.9-0.5-0.6
Short access day 10 total infusions0.00.00.2-0.0-0.0-0.1-0.1-0.1-0.40.1-0.1-0.4-0.1-0.1
Short access total infusions0.30.31.1-0.3-0.2-0.3-0.30.3-0.90.5-0.5-1.0-0.5-0.6
Short access day 1 locomotion0.30.30.40.70.70.70.6-0.60.6-0.50.40.40.30.2
Short access day 10 total locomotion4.75.36.52.32.32.32.3-2.32.6-2.32.22.52.22.1
Short access total locomotion0.50.60.90.80.80.80.8-0.81.0-0.70.60.70.50.4
One hour access (0.3 mA shock)0.10.10.3-0.4-0.5-0.5-0.50.3-0.30.5-0.3-0.1-0.3-0.2
Compulsive drug intake0.90.91.1-1.0-0.9-0.9-0.90.9-1.00.9-0.9-1.0-0.9-0.8
One hour access (shock baseline)0.20.30.90.40.20.20.3-0.50.8-0.30.51.00.50.6
Social response proportion0.40.40.70.80.90.90.8-0.80.5-0.60.50.20.40.3
Social responses5.67.211.63.13.03.02.9-2.93.4-2.62.12.41.81.5
Social time0.60.71.6-1.0-0.9-0.8-0.80.8-1.30.9-0.7-0.9-0.6-0.4
Soleus weight7.823.027.9-5.3-5.3-5.2-5.25.1-5.14.8-4.4-4.2-4.1-3.7
Bone: stiffness3.86.07.6-2.5-2.5-2.5-2.52.5-2.82.3-2.3-2.6-2.3-2.2
Tibialis anterior weight0.82.93.9-1.8-1.8-1.8-1.81.7-2.01.5-1.5-1.7-1.5-1.3
Time to tail flick, vehicle, before self-admin0.20.20.80.50.40.30.3-0.20.9-0.3-0.10.2-0.2-0.5
Time to tail flick, vehicle, after self-admin0.50.50.90.60.60.60.7-0.70.5-0.70.90.80.91.0
Time to tail flick, test, before self-admin0.20.20.80.1-0.0-0.0-0.10.30.80.3-0.60.1-0.7-0.9
Time to tail flick, test, after self-admin0.10.10.30.20.30.30.3-0.1-0.20.0-0.1-0.5-0.2-0.3
Delta time to tail flick, vehicle, before/after SA0.20.21.0-0.3-0.2-0.1-0.1-0.0-1.00.00.4-0.20.50.7
Delta time to tail flick, test, before/after SA0.50.40.90.50.60.60.6-0.70.1-0.60.80.50.91.0
Tibia length1.13.14.81.81.71.81.7-1.72.2-1.71.62.01.51.4
Ambulatory time before self-admin0.30.30.4-0.3-0.6-0.6-0.60.50.70.4-0.50.6-0.5-0.5
Ambulatory time after self-admin0.30.30.40.60.70.70.6-0.60.0-0.60.5-0.10.50.4
Bone: tissue strength2.52.42.8-1.6-1.6-1.6-1.61.6-1.71.6-1.5-1.6-1.5-1.4
Total heroin consumption1.41.62.41.51.41.41.3-1.31.5-1.31.11.11.00.8
Bone: trabecular number0.20.30.50.70.70.70.6-0.50.4-0.50.0-0.4-0.2-0.4
Bone: trabecular spacing0.40.52.0-0.0-0.1-0.00.1-0.20.5-0.30.81.41.01.3
Bone: trabecular thickness1.72.15.7-0.7-0.7-0.7-0.91.1-0.81.2-1.8-2.0-2.1-2.4
Bone: trabecular tissue density1.52.13.3-1.8-1.8-1.7-1.71.6-1.71.5-1.1-1.0-0.9-0.6
Water consumed over 24 hours1.11.41.9-1.0-1.0-1.0-1.11.1-1.11.1-1.3-1.4-1.3-1.3
Number of responses in last shaping day0.60.63.40.60.30.30.3-0.31.8-0.30.21.60.20.1