LOC102551980

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	PL	alternative polyA	XM_039087579.1	0.02	0.01	1.0e-02	0	0	0	0	3.1e-01	1.1e-01	2.9e-01	3.3e-01
2	PL	isoform ratio	XM_039087579.1	0.02	0.01	8.0e-03	0.01	0	0	0	9.7e-03	1.0e-01	3.1e-01	2.5e-01
3	Brain	intron excision ratio	chr10_107141201_107149814	0.03	0.02	5.5e-03	0.01	0.02	0.01	0.01	3.6e-02	4.9e-03	2.6e-02	7.5e-02
4	NAcc	alternative polyA	XM_039087579.1	0.02	0.01	4.6e-03	0.02	0.01	0.01	0.02	8.8e-04	8.8e-03	1.5e-02	4.1e-03
5	NAcc	alternative polyA	XM_039087580.1	0.02	0.01	5.9e-03	0.02	0.01	0	0.01	1.6e-03	1.6e-02	1.2e-01	6.9e-03
6	NAcc	isoform ratio	XM_039087579.1	0.02	0.01	7.6e-04	0.01	0.02	0.01	0.01	1.6e-02	1.8e-03	1.1e-02	1.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6
Bone: apparent density	0.2	0.3	0.4	0.5	-0.5	0.1	-0.6	0.6	0.5
Area under the delay curve	2.6	2.7	3.1	-1.8	1.6	-1.6	1.6	-1.6	-1.7
BMI with tail	0.8	2.6	4.8	2.2	-1.4	2.0	-1.3	1.3	1.3
BMI without tail	5.5	11.3	18.5	3.3	-3.5	4.3	-3.3	3.3	2.2
Body weight	3.5	14.8	21.5	4.6	-3.8	4.3	-3.5	3.5	3.1
Weight adjusted by age	3.2	3.6	5.0	2.2	-2.1	1.6	-1.8	1.8	1.9
Bone surface	0.4	0.6	0.8	0.9	-0.8	0.7	-0.8	0.8	0.7
Bone volume	0.3	0.5	0.6	0.8	-0.8	0.6	-0.8	0.8	0.7
Breakpoint value in progressive ratio session	0.9	1.0	2.1	-0.4	1.0	-0.1	1.4	-1.4	-0.8
Number of licking bursts	0.2	0.2	0.4	0.3	-0.6	0.4	-0.6	0.6	0.3
Context. condit. distance diff. score	0.6	0.7	1.3	0.7	-0.9	1.1	-0.9	0.9	0.3
Locomotion velocity, session 1	1.6	1.7	2.5	-1.2	1.5	-1.6	1.4	-1.4	-0.5
Locomotion distance, session 1	1.0	1.3	2.0	-1.1	1.1	-1.0	1.2	-1.2	-1.4
Locomotion velocity, session 2	4.5	5.3	5.6	-2.4	2.4	-2.2	2.3	-2.3	-2.3
Locomotion distance, session 2	0.1	0.1	0.7	-0.4	0.2	-0.1	0.0	-0.0	-0.8
Locomotion velocity, session 3	3.3	3.9	5.7	-2.0	2.0	-2.4	1.8	-1.8	-1.7
Locomotion distance, session 3	5.4	5.9	6.8	-2.5	2.4	-2.6	2.3	-2.3	-2.4
Stereotopy head waving bouts, day 3	0.1	0.1	0.2	-0.1	0.3	-0.4	0.5	-0.5	-0.1
Stereotopy head waving duration, day 3	0.0	0.0	0.1	0.3	-0.1	0.2	0.1	-0.1	0.0
Locomotion velocity, session 7	1.1	1.2	1.4	-1.2	1.1	-1.1	1.1	-1.1	-1.2
Locomotion distance, session 7	3.6	4.5	6.1	-2.5	2.1	-1.9	1.9	-1.9	-2.4
Stereotopy head waving bouts, day 7	0.9	1.0	1.9	1.3	-1.0	1.4	-0.7	0.7	0.7
Stereotopy head waving duration, day 7	0.9	1.1	1.7	1.3	-1.1	1.1	-0.9	0.9	0.9
Locomotion velocity, session 8	0.3	0.3	0.7	-0.5	0.4	-0.9	0.2	-0.2	-0.8
Locomotion distance, session 8	0.5	0.8	1.5	0.6	-1.0	1.2	-1.0	1.0	-0.4
Degree of sensitization distance	0.7	0.7	0.9	0.5	-0.8	0.9	-1.0	1.0	0.6
Degree of sensitization stereotypy	0.9	1.0	1.7	1.3	-1.0	1.3	-0.7	0.7	0.7
Conditioned locomotion	5.3	6.3	7.2	2.5	-2.7	2.5	-2.6	2.6	2.0
Cocaine response after cond. corrected	0.5	0.6	1.0	-0.8	0.9	-1.0	0.7	-0.7	-0.4
Cocaine response after cond. not corrected	1.2	1.4	1.6	-1.2	1.3	-1.3	1.2	-1.2	-1.0
Cocaine response before conditioning	0.5	0.7	1.7	-0.8	0.7	-0.4	0.7	-0.7	-1.3
Saline control response	1.8	2.3	3.9	1.1	-1.6	0.8	-2.0	2.0	1.3
Bone: connectivity density	0.0	0.1	0.1	-0.1	-0.1	-0.3	-0.4	0.4	-0.1
Bone: cortical apparent density	3.5	4.6	6.2	-2.4	2.2	-2.5	2.0	-2.0	-1.7
Bone: cortical area	7.6	11.4	17.9	4.2	-3.5	3.0	-3.2	3.2	2.9
Bone: cortical porosity	0.5	0.6	1.3	1.1	-0.4	1.0	-0.1	0.1	1.1
Bone: cortical porosity	0.9	1.0	1.8	1.4	-0.8	1.2	-0.5	0.5	1.2
Bone: cortical thickness	5.9	9.8	14.9	3.9	-3.3	2.2	-3.0	3.0	3.1
Bone: cortical thickness	2.4	2.8	4.2	2.1	-1.7	1.3	-1.5	1.5	1.8
Bone: cortical tissue density	4.1	5.3	7.0	-2.6	2.3	-2.6	2.2	-2.2	-1.8
Condit. Reinf. active minus inactive responses	2.3	2.6	2.9	1.7	-1.7	1.4	-1.7	1.7	1.5
Condit. Reinf. active-inactive response ratio	0.7	0.8	1.0	1.0	-0.9	0.3	-1.0	1.0	0.8
Condit. Reinf. active responses	4.4	5.4	5.7	2.3	-2.4	2.4	-2.4	2.4	2.1
Condit. Reinf. inactive responses	1.3	1.5	2.4	1.1	-1.2	1.5	-1.2	1.2	1.1
Incentive salience index mean	1.7	2.1	2.2	1.5	-1.5	1.5	-1.5	1.5	1.2
Condit. Reinf. lever presses	0.0	0.1	0.2	-0.1	0.1	0.4	0.1	-0.1	-0.3
Condit. Reinf. active minus inactive responses	1.9	2.3	3.6	1.9	-1.6	1.2	-1.5	1.5	1.4
Condit. Reinf. active-inactive response ratio	4.1	4.3	6.1	2.5	-2.1	1.8	-1.9	1.9	2.2
Condit. Reinf. active responses	0.5	0.6	1.2	1.1	-0.8	0.6	-0.8	0.8	0.5
Condit. Reinf. inactive responses	0.8	1.0	1.5	-1.0	0.9	-1.1	0.9	-0.9	-1.2
Condit. Reinf. lever presses	0.2	0.2	0.3	0.4	-0.5	0.6	-0.6	0.6	0.1
Condit. Reinf. lever reinforcers received	0.5	0.7	1.2	1.1	-0.8	0.8	-0.8	0.8	0.5
Conditioned reinforcement - actives	0.1	0.1	0.1	-0.1	-0.3	0.2	-0.3	0.3	-0.1
Conditioned reinforcement - inactives	0.0	0.0	0.1	-0.1	-0.4	0.2	-0.2	0.2	0.0
Conditioned locomotion	0.1	0.1	0.2	-0.2	0.0	0.3	-0.3	0.3	-0.5
Patch foraging indifference point 0 sec	0.1	0.1	0.4	-0.4	0.2	-0.6	0.1	-0.1	-0.2
Patch foraging indifference point AUC	0.2	0.2	0.4	0.3	-0.2	0.6	-0.4	0.4	0.5
Delay disc. indifference point, 0s delay	0.0	0.1	0.2	-0.0	-0.2	-0.5	0.1	-0.1	-0.1
Delay disc. indifference point, 16s delay	2.3	2.4	4.3	-1.8	1.1	-1.1	1.4	-1.4	-2.1
Delay disc. indifference point, 2s delay	0.5	0.5	0.7	-0.6	0.8	-0.5	0.8	-0.8	-0.7
Delay disc. indifference point, 24s delay	6.3	6.1	6.9	-2.4	2.6	-2.4	2.6	-2.6	-2.3
Delay disc. indifference point, 4s delay	1.2	1.3	3.5	-1.3	1.0	-1.9	0.6	-0.6	-0.9
Delay disc. indifference point, 8s delay	1.7	1.7	2.5	-1.3	1.3	-1.6	1.3	-1.3	-1.0
Indifference point function ln k	0.7	1.0	1.9	-1.0	0.8	-1.4	0.9	-0.9	-1.1
Indifference point function log k	0.7	1.0	1.9	-1.0	0.8	-1.4	0.9	-0.9	-1.1
Patch foraging total patch changes 0 sec	0.1	0.1	0.4	-0.5	0.2	-0.7	0.1	-0.1	-0.3
Patch foraging total patch changes 12 sec	0.0	0.0	0.1	-0.2	0.3	0.0	0.1	-0.1	0.2
Patch foraging total patch changes 18 sec	0.2	0.2	0.4	-0.6	0.4	-0.5	0.3	-0.3	-0.6
Patch foraging total patch changes 24 sec	0.1	0.1	0.2	0.1	-0.1	-0.1	-0.5	0.5	0.3
Patch foraging total patch changes 6 sec	0.2	0.3	0.6	0.5	-0.4	0.5	-0.6	0.6	0.8
Patch foraging time to switch 0 sec	0.3	0.4	0.7	-0.6	0.6	-0.3	0.8	-0.8	-0.6
Patch foraging water rate 0 sec	0.4	0.6	1.2	0.4	-0.8	0.3	-1.1	1.1	0.4
Patch foraging water rate 12 sec	0.0	0.1	0.1	0.1	-0.3	-0.0	-0.4	0.4	-0.0
Patch foraging water rate 18 sec	0.4	0.5	0.8	0.7	-0.9	0.5	-0.9	0.9	0.1
Patch foraging water rate 24 sec	0.6	0.9	1.5	0.9	-1.2	0.7	-1.1	1.1	0.1
Patch foraging water rate 6 sec	0.2	0.2	0.6	-0.5	0.2	-0.6	0.3	-0.3	-0.8
Seeking ratio, delayed vs. immediate footshock	1.2	1.4	2.3	1.1	-1.0	0.7	-1.5	1.5	1.2
Distance traveled before self-admin	0.2	0.2	0.3	0.2	-0.2	-0.3	-0.6	0.6	0.4
Distance traveled after self-admin	0.2	0.2	0.4	-0.2	-0.5	0.6	-0.6	0.6	-0.1
Extensor digitorum longus weight	0.4	1.6	3.3	1.4	-1.3	1.8	-1.0	1.0	0.7
Bone: elastic displacement	1.4	1.6	2.0	1.2	-1.3	0.7	-1.4	1.4	1.3
Bone: elastic work	7.5	9.6	13.1	3.5	-3.1	2.1	-3.0	3.0	3.6
Bone: endosteal estimation	0.2	0.4	1.7	0.6	-0.3	1.3	0.1	-0.1	-0.4
Bone: endosteal perimeter	0.6	1.3	2.2	1.5	-1.2	1.2	-1.0	1.0	0.9
Epididymis fat weight	0.8	1.9	3.7	1.5	-1.3	1.9	-1.2	1.2	0.8
Delta time in closed arm before/after self-admin	0.1	0.1	0.2	-0.2	-0.0	-0.5	0.1	-0.1	0.2
Delta time in open arm before/after self-admin	0.4	0.4	0.6	-0.8	0.6	-0.5	0.5	-0.5	-0.7
Diff in mean of infusions in LGA sessions	1.4	1.5	2.3	-1.1	1.5	-0.9	1.4	-1.4	-1.1
Delay discount exponential model param	3.7	3.9	4.3	2.1	-2.0	2.0	-1.9	1.9	1.9
Extinction: sum of active levers before priming	1.9	1.9	2.6	-1.0	1.6	-1.4	1.6	-1.6	-0.7
Active lever presses in extinction session 6	4.2	4.1	5.4	-1.6	2.3	-1.7	2.3	-2.3	-1.8
Bone: final force	6.3	10.2	15.7	4.0	-3.3	3.0	-3.0	3.0	2.7
Bone: final moment	7.3	11.8	18.1	4.3	-3.5	3.2	-3.2	3.2	3.0
Food consumed during 24 hour testing period	0.4	0.5	0.6	0.5	-0.7	0.5	-0.8	0.8	0.8
Glucose	2.8	4.3	6.8	-1.5	2.2	-1.9	2.6	-2.6	-1.1
Heart weight	2.4	3.4	5.4	2.3	-1.8	2.2	-1.5	1.5	1.6
Delay discount hyperbolic model param	3.4	3.6	4.1	2.0	-1.9	2.0	-1.8	1.8	1.9
Intermittent access intake day 1-15 change	0.1	0.1	0.3	-0.6	-0.0	-0.3	0.0	-0.0	-0.2
Intermittent access intake escalation	0.1	0.1	0.4	-0.6	0.1	-0.0	0.0	-0.0	-0.4
Intermittent access intake escalation 2	0.0	0.0	0.0	-0.2	0.0	0.1	-0.0	0.0	0.0
Intermitt. access day 1 inactive lever presses	0.0	0.0	0.1	0.2	-0.2	0.1	-0.2	0.2	0.3
Intermitt. access day 15 inactive lever presses	0.3	0.3	0.6	0.1	-0.7	0.1	-0.8	0.8	-0.1
Intermitt. access escalation Index	1.0	0.9	1.1	0.9	-1.0	0.8	-1.0	1.0	1.0
Intermittent access day 1 total infusions	1.1	1.3	2.2	1.2	-1.0	1.5	-1.1	1.1	0.9
Intermittent access day 15 total infusions	0.3	0.3	0.6	0.3	-0.5	0.8	-0.6	0.6	0.3
Intermittent access terminal intake (last 3 days)	0.3	0.4	0.5	0.4	-0.5	0.7	-0.7	0.7	0.5
Intermittent access total infusions	0.5	0.6	0.8	0.6	-0.8	0.8	-0.9	0.9	0.5
Intermittent access day 1 locomotion	0.1	0.1	0.1	-0.0	-0.1	0.2	-0.3	0.3	-0.3
Intermittent access day 15 total locomotion	0.1	0.1	0.3	0.1	-0.2	0.1	-0.6	0.6	-0.0
Intermittent access total locomotion	0.1	0.1	0.1	-0.2	-0.0	0.0	-0.3	0.3	-0.4
Intermittent access standard deviation	3.0	3.1	3.8	-2.0	1.4	-1.9	1.9	-1.9	-1.6
Left kidney weight	0.4	1.2	3.5	1.9	-0.9	1.2	-0.4	0.4	0.9
Right kidney weight	0.2	0.5	1.7	1.3	-0.8	0.7	-0.3	0.3	0.5
Cocaine induced anxiety	0.5	0.6	2.2	0.9	-0.4	0.0	-0.5	0.5	1.5
Post-drug Anxiety	0.4	0.4	1.4	-0.5	0.5	-1.2	0.5	-0.5	-0.0
Baseline Anxiety	4.0	4.3	6.5	-2.2	1.7	-2.0	1.9	-1.9	-2.5
Tail length	4.4	13.3	18.7	3.4	-3.9	4.3	-3.8	3.8	2.5
Length with tail	1.8	6.8	8.9	3.0	-2.7	2.8	-2.4	2.4	2.1
Length without tail	0.3	0.7	1.3	0.2	0.9	-0.8	1.2	-1.2	-0.1
Times rat made contact with spout	1.4	1.6	3.3	1.1	-1.1	1.1	-1.1	1.1	1.8
Lifetime Intake	0.1	0.1	0.1	0.1	-0.3	0.3	-0.4	0.4	0.2
Liver weight, left	0.1	0.2	0.3	0.2	0.3	0.4	0.6	-0.6	-0.1
Liver weight, right	1.6	2.7	4.5	1.9	-1.6	2.1	-1.4	1.4	1.2
Locomotor activity	0.8	1.2	1.8	-1.0	1.1	-0.6	1.4	-1.4	-1.2
Locomotor testing distance	0.6	1.0	1.5	-0.7	0.8	-0.5	1.2	-1.2	-1.2
Locomotor testing rearing	0.9	1.4	2.1	-1.4	1.2	-0.9	1.2	-1.2	-1.3
Locomotion in novel chamber	0.0	0.0	0.1	-0.0	-0.1	-0.3	0.2	-0.2	-0.2
Locomotion in novel chamber post-restriction	2.8	3.3	4.0	1.9	-1.8	2.0	-1.8	1.8	1.7
Fecal boli incidents, locomotor time 1	0.1	0.1	0.3	-0.1	0.3	0.6	0.0	-0.0	-0.4
Change in fecal boli incidents, locomotor task	3.5	3.3	4.2	-1.8	2.0	-1.8	2.1	-2.1	-1.1
Time >=10cm from walls, locomotor time 1	0.2	0.2	0.4	-0.1	-0.5	-0.2	-0.6	0.6	-0.1
Bouts of movement, locomotor time 1	0.3	0.3	0.5	-0.5	0.7	-0.5	0.7	-0.7	-0.4
Total resting periods, locomotor time 1	0.6	0.6	1.0	-0.8	1.0	-0.8	0.8	-0.8	-0.5
Rest time, locomotor task time 1	0.0	0.0	0.2	0.1	-0.0	0.4	0.1	-0.1	0.0
Distance moved, locomotor task time 1	0.7	0.8	1.1	-1.0	0.8	-1.1	0.8	-0.8	-0.8
Vertical activity count, locomotor time 1	0.0	0.0	0.0	-0.0	-0.2	0.0	-0.2	0.2	-0.2
Time >=10cm from walls, locomotor time 2	1.1	1.2	1.6	1.1	-1.1	0.6	-1.3	1.3	1.0
Bouts of movement, locomotor time 2	1.1	1.1	1.6	-0.9	1.1	-0.8	1.3	-1.3	-1.0
Total resting periods, locomotor time 2	0.5	0.5	0.8	-0.6	0.7	-0.4	0.9	-0.9	-0.8
Rest time, locomotor task time 2	0.1	0.1	0.6	0.3	0.0	0.8	0.0	-0.0	0.1
Distance moved, locomotor task time 2	0.1	0.2	0.6	-0.5	0.1	-0.8	0.2	-0.2	-0.3
Vertical activity count, locomotor time 2	0.1	0.2	0.3	0.4	-0.5	0.6	-0.3	0.3	-0.3
Light reinforcement 1	1.3	2.4	2.8	1.5	-1.5	1.4	-1.7	1.7	1.6
Light reinforcement 2	1.9	2.6	3.0	1.7	-1.6	1.7	-1.5	1.5	1.5
Bone: marrow area	0.2	0.4	1.5	0.6	-0.2	1.2	0.1	-0.1	-0.4
Bone: maximum diameter	1.7	3.1	5.5	2.3	-1.8	1.7	-1.6	1.6	1.3
Bone: maximum force	7.3	12.7	19.6	4.4	-3.7	3.6	-3.2	3.2	2.9
Bone: maximum moment	8.4	14.5	22.3	4.7	-3.9	3.8	-3.5	3.5	3.3
Mean time between licks in bursts	2.2	3.1	3.6	-1.9	1.7	-1.8	1.7	-1.7	-1.7
Mean num. licks in bursts	0.2	0.2	0.6	0.5	-0.2	0.4	-0.3	0.3	0.8
Cd content in liver	1.7	1.8	2.0	-1.3	1.4	-1.1	1.4	-1.4	-1.4
Co content in liver	0.4	0.5	0.6	-0.6	0.7	-0.5	0.8	-0.8	-0.7
Cu content in liver	0.1	0.1	0.2	-0.1	0.0	-0.5	-0.2	0.2	0.3
Fe content in liver	1.8	2.1	3.1	-1.4	1.5	-1.0	1.5	-1.5	-1.8
K content in liver	0.9	0.9	1.6	0.4	-1.0	0.8	-1.3	1.3	0.6
Mg content in liver	0.2	0.2	0.4	-0.7	-0.1	0.1	-0.4	0.4	-0.6
Mn content in liver	0.1	0.2	0.3	0.2	-0.4	0.2	-0.5	0.5	0.3
Na content in liver	0.3	0.3	0.7	-0.7	0.6	-0.8	0.4	-0.4	-0.5
Rb content in liver	1.2	1.4	2.4	0.9	-1.2	1.0	-1.6	1.6	0.7
Se content in liver	0.1	0.1	0.2	-0.3	-0.2	-0.2	-0.5	0.5	0.3
Sr content in liver	0.2	0.2	0.7	-0.2	0.3	-0.9	0.3	-0.3	0.4
Zn content in liver	0.1	0.1	0.2	-0.3	0.3	-0.1	0.4	-0.4	-0.5
Bone: minimum diameter	3.1	5.8	8.2	2.9	-2.5	2.0	-2.4	2.4	2.3
Time in familiar zone, hab. session 1	0.0	0.0	0.1	0.1	0.0	0.0	0.2	-0.2	0.3
Time in novel zone, hab. session 1	0.0	0.0	0.1	-0.2	0.1	-0.2	-0.2	0.2	0.0
Total zone transitions, hab. session 1	0.1	0.1	0.2	-0.4	0.2	-0.2	0.3	-0.3	-0.5
Total locomotion distance, hab. session 1	0.5	0.7	1.3	0.8	-0.9	1.2	-0.8	0.8	0.4
Locomotion velocity, hab. session 1	0.6	0.9	1.8	0.9	-1.0	1.4	-0.9	0.9	0.4
Time in familiar zone, hab. session 2	0.3	0.3	0.4	-0.6	0.6	-0.2	0.6	-0.6	-0.5
Time in novel zone, hab. session 2	0.0	0.0	0.2	-0.0	0.0	-0.4	-0.1	0.1	-0.1
Total zone transitions, hab. session 2	0.3	0.4	0.6	0.5	-0.7	0.8	-0.6	0.6	0.0
Total locomotion distance, hab. session 2	1.7	2.2	3.4	1.4	-1.7	1.9	-1.5	1.5	0.8
Locomotion velocity, hab. session 2	2.1	2.9	4.1	1.6	-1.9	2.0	-1.7	1.7	1.0
Novel to familiar place preference ratio	2.3	2.4	3.8	1.8	-1.5	1.0	-1.5	1.5	2.0
Novelty place preference	2.4	2.4	3.9	1.8	-1.5	1.0	-1.5	1.5	2.0
Time in novel zone, NPP test	2.0	2.1	3.3	1.6	-1.4	0.9	-1.3	1.3	1.8
Total zone transitions, NPP test	0.1	0.2	0.8	-0.3	-0.1	0.3	-0.1	0.1	-0.9
Total locomotion distance, NPP test	0.5	0.7	1.9	0.5	-0.9	1.4	-0.8	0.8	-0.2
Locomotion velocity, NPP test	0.6	0.9	2.1	0.7	-1.1	1.4	-0.9	0.9	0.1
Intraocular pressure	0.9	1.3	2.1	1.1	-1.2	1.5	-1.2	1.2	0.4
Delta distance traveled before/after self-admin	0.5	0.5	1.1	-1.1	0.6	-0.2	0.6	-0.6	-0.9
Delta ambulatory time before/after self-admin	0.9	1.0	1.8	-1.3	1.2	-0.3	0.9	-0.9	-1.1
Parametrial fat weight	2.0	3.8	6.6	1.9	-1.8	2.6	-1.7	1.7	1.9
Pavlov. Cond. lever latency	0.7	0.8	2.3	-0.9	0.7	-0.4	0.8	-0.8	-1.5
Pavlov. Cond. magazine entry latency	1.0	1.3	2.7	1.2	-1.1	0.6	-1.1	1.1	1.6
Pavlov. Cond. change in total contacts	0.1	0.1	0.3	0.2	-0.0	0.0	0.1	-0.1	0.6
Pavlov. Cond. index score	2.2	2.8	4.3	1.7	-1.6	1.3	-1.6	1.6	2.1
Pavlov. Cond. latency score	1.7	2.2	3.9	1.5	-1.4	1.1	-1.4	1.4	2.0
Pavlov. Cond. lever contacts	0.5	0.6	1.0	0.7	-0.7	0.6	-0.7	0.7	1.0
Pavlov. Cond. magazine entry number	1.0	1.3	2.9	-1.2	1.0	-0.7	0.9	-0.9	-1.7
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.3	0.8	-0.8	1.1	-0.9	0.9	0.5
Pavlov. Cond. lever-magazine prob. diff.	2.0	2.5	3.9	1.6	-1.5	1.1	-1.6	1.6	2.0
Pavlov. Cond. response bias	0.9	1.1	2.4	1.1	-0.9	0.6	-0.9	0.9	1.5
Pavlov. Cond. lever latency	0.9	1.2	2.2	-1.1	1.1	-1.5	1.0	-1.0	-0.6
Pavlov. Cond. magazine entry latency	1.6	1.8	3.2	-1.5	1.3	-0.5	1.4	-1.4	-1.8
Pavlov. Cond. change in total contacts	0.1	0.2	0.6	-0.2	0.3	0.1	0.3	-0.3	-0.8
Pavlov. Cond. index score	0.1	0.2	0.5	-0.3	0.2	0.5	0.3	-0.3	-0.7
Pavlov. Cond. latency score	0.1	0.1	0.4	-0.1	0.0	0.6	0.2	-0.2	-0.6
Pavlov. Cond. lever contacts	1.2	1.6	2.6	1.2	-1.3	1.6	-1.3	1.3	0.7
Pavlov. Cond. magazine entry number	1.5	1.8	3.3	1.5	-1.2	0.5	-1.3	1.3	1.8
Pavlov. Cond. intertrial magazine entries	2.0	2.6	3.4	1.6	-1.8	1.1	-1.8	1.8	1.4
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.7	-0.4	0.3	0.4	0.5	-0.5	-0.9
Pavlov. Cond. response bias	0.1	0.1	0.7	0.2	-0.3	0.8	-0.2	0.2	-0.2
Time in closed arm before self-admin	0.1	0.1	0.4	-0.2	0.6	-0.2	0.3	-0.3	-0.4
Time in closed arm after self-admin	1.2	1.3	1.9	-1.1	1.3	-1.4	1.1	-1.1	-0.7
Time in open arm before self-admin	0.5	0.6	1.0	0.9	-0.7	0.5	-0.7	0.7	1.0
Time in open arm after self-admin	0.0	0.0	0.0	0.0	0.2	-0.0	0.1	-0.1	-0.0
Bone: periosteal estimation	2.7	5.6	9.5	3.1	-2.4	2.6	-2.0	2.0	1.7
Bone: periosteal perimeter	3.3	5.5	9.5	3.1	-2.3	2.0	-2.1	2.1	2.3
Bone: post-yield work	0.0	0.0	0.1	0.2	-0.1	0.1	0.0	-0.0	-0.3
Progressive ratio test 1 active lever presses	0.4	0.4	0.7	0.5	-0.5	0.7	-0.8	0.8	0.4
Progressive ratio test 1 breakpoint	1.0	1.0	1.5	0.9	-0.8	1.0	-1.2	1.2	0.8
Progressive ratio test 1 inactive lever presses	0.6	0.7	1.2	0.6	-0.7	0.5	-1.1	1.1	0.7
Progressive ratio test 2 active lever presses	0.4	0.4	0.7	0.6	-0.6	0.9	-0.6	0.6	0.4
Progressive ratio test 2 breakpoint	0.5	0.5	0.9	0.6	-0.8	0.9	-0.7	0.7	0.4
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.0	0.1	-0.1	-0.1	-0.1	0.1	0.1
Incentive Sensitization - Responses	1.0	1.0	1.4	0.9	-1.1	1.2	-0.9	0.9	0.9
Incentive Sensitization - Breakpoint	0.8	0.8	1.1	0.9	-1.0	1.0	-0.8	0.8	0.9
Sum of active levers in priming session hrs 5-6	0.2	0.1	0.3	0.1	0.1	0.5	0.6	-0.6	0.1
Progressive ratio	0.5	0.6	0.9	-0.3	0.8	0.1	0.9	-0.9	-1.0
Food seeking constrained by brief footshock	0.2	0.3	0.5	-0.6	0.6	-0.7	0.5	-0.5	-0.3
Seeking ratio, punishment vs. effort	0.3	0.3	0.5	0.1	-0.5	-0.3	-0.7	0.7	0.7
Retroperitoneal fat weight	4.4	14.6	22.0	4.0	-3.7	4.7	-3.7	3.7	3.0
Reaction time number correct	0.2	0.3	0.4	-0.1	-0.5	0.3	-0.6	0.6	-0.7
Reaction time mean minus median	0.5	0.6	1.1	-0.7	0.9	-0.3	1.1	-1.1	-0.4
Reaction time mean minus median AUC	0.1	0.1	0.1	-0.2	0.3	-0.1	0.4	-0.4	-0.1
Reaction time num false alarms	0.0	0.0	0.1	0.2	0.1	0.2	0.3	-0.3	0.0
Reaction time num false alarms AUC	0.1	0.2	0.3	-0.2	0.4	-0.1	0.6	-0.6	-0.4
Reaction time trials correct on left	0.2	0.3	0.4	-0.1	-0.5	0.3	-0.6	0.6	-0.7
Reaction time trials on left	0.2	0.3	0.5	-0.1	-0.5	0.3	-0.6	0.6	-0.7
Reaction time mean	0.3	0.4	0.8	0.6	-0.6	0.9	-0.3	0.3	0.6
Reaction time mean AUC	0.3	0.5	1.0	0.6	-0.8	1.0	-0.5	0.5	0.4
Median of all reaction times	0.3	0.5	0.7	0.7	-0.8	0.8	-0.5	0.5	0.7
Reaction time omissions	0.1	0.1	0.3	-0.5	0.2	-0.1	0.3	-0.3	-0.4
Reaction time false alarm rate	0.2	0.3	0.7	-0.1	0.6	-0.3	0.8	-0.8	0.0
Reaction time premature initiation rate	0.7	0.9	1.3	-1.0	0.9	-0.9	1.1	-1.1	-0.7
Reaction time premature initiations	0.3	0.5	0.9	-0.9	0.4	-0.5	0.7	-0.7	-1.0
Std. dev. reaction times	0.3	0.4	0.7	-0.6	0.5	-0.2	0.8	-0.8	-0.6
Reaction time trials completed	0.2	0.3	0.5	-0.1	-0.5	0.3	-0.6	0.6	-0.7
Reaction time trials AUC	0.2	0.3	0.5	-0.0	-0.6	0.3	-0.7	0.7	-0.6
Run reversals in cocaine runway, females	0.1	0.1	0.1	-0.1	0.2	0.2	0.2	-0.2	-0.4
Run reversals in cocaine runway, males	0.9	0.9	1.4	1.0	-0.6	1.0	-0.9	0.9	1.2
Latency to leave start box in cocaine runway	0.2	0.2	1.0	0.2	0.3	1.0	0.1	-0.1	-0.3
Latency to leave start box in cocaine runway, F	0.4	0.4	1.7	0.5	-0.0	1.3	-0.5	0.5	-0.2
Latency to leave start box in cocaine runway, M	0.1	0.1	0.3	0.1	0.1	0.5	0.3	-0.3	0.2
Std. dev. time between licks in bursts	0.4	0.4	0.8	0.1	-0.8	0.5	-0.9	0.9	-0.4
Total sessions with >9 infusions	0.2	0.2	0.4	-0.4	0.4	-0.1	0.5	-0.5	-0.6
Short access day 1 total inactive lever presses	0.1	0.2	0.8	0.3	-0.2	0.9	0.0	-0.0	-0.1
Short access day 10 total inactive lever presses	1.2	1.3	2.3	1.0	-1.5	0.8	-1.1	1.1	1.2
Short access day 1 total infusions	2.1	2.3	2.8	-1.5	1.4	-1.6	1.7	-1.7	-1.1
Short access day 10 total infusions	0.1	0.1	0.1	0.2	-0.3	0.3	-0.3	0.3	0.3
Short access total infusions	0.0	0.0	0.1	-0.3	0.1	-0.3	0.1	-0.1	0.1
Short access day 1 locomotion	0.6	0.7	1.3	-0.6	0.7	-1.2	0.9	-0.9	-0.3
Short access day 10 total locomotion	0.8	0.9	1.9	-1.1	1.0	-1.4	0.7	-0.7	-0.5
Short access total locomotion	0.6	0.6	1.4	-0.8	0.9	-1.2	0.6	-0.6	-0.4
One hour access (0.3 mA shock)	1.6	1.9	2.5	1.2	-1.6	1.5	-1.4	1.4	1.1
Compulsive drug intake	0.9	0.9	1.3	0.9	-1.1	0.8	-1.0	1.0	0.7
One hour access (shock baseline)	0.6	0.7	1.4	0.7	-0.8	1.2	-0.9	0.9	0.6
Social response proportion	1.7	1.9	2.2	-1.2	1.2	-1.3	1.4	-1.4	-1.5
Social responses	0.6	0.7	1.5	-0.8	0.7	-1.2	0.7	-0.7	-0.8
Social time	0.0	0.1	0.1	0.0	0.1	-0.2	0.3	-0.3	-0.3
Soleus weight	1.8	5.2	5.9	2.2	-2.4	1.9	-2.4	2.4	2.3
Bone: stiffness	1.5	2.4	4.5	2.1	-1.6	2.0	-1.1	1.1	0.8
Tibialis anterior weight	0.3	1.0	1.8	1.0	-1.0	1.3	-0.9	0.9	0.9
Time to tail flick, vehicle, before self-admin	0.2	0.2	0.4	0.1	-0.7	0.1	-0.6	0.6	0.0
Time to tail flick, vehicle, after self-admin	0.5	0.5	0.8	-0.6	0.9	-0.6	0.8	-0.8	-0.8
Time to tail flick, test, before self-admin	0.3	0.3	0.7	-0.8	0.8	-0.1	0.1	-0.1	-0.7
Time to tail flick, test, after self-admin	2.1	2.2	3.1	-1.8	1.5	-1.6	1.2	-1.2	-1.4
Delta time to tail flick, vehicle, before/after SA	0.1	0.1	0.3	0.1	0.4	0.5	0.1	-0.1	0.0
Delta time to tail flick, test, before/after SA	0.9	0.8	1.5	-0.4	0.8	-1.0	1.2	-1.2	-0.3
Tibia length	10.9	30.9	43.8	6.6	-5.8	4.8	-5.2	5.2	5.5
Ambulatory time before self-admin	0.5	0.5	0.8	0.5	-0.7	-0.3	-0.9	0.9	0.7
Ambulatory time after self-admin	0.0	0.0	0.1	-0.4	0.1	-0.0	-0.1	0.1	-0.3
Bone: tissue strength	1.7	1.7	2.4	1.5	-1.4	1.4	-1.3	1.3	0.6
Total heroin consumption	0.5	0.6	1.2	0.2	1.1	-0.1	1.1	-1.1	-0.5
Bone: trabecular number	0.0	0.1	0.2	0.1	-0.1	-0.1	-0.3	0.3	0.4
Bone: trabecular spacing	0.2	0.3	0.7	0.2	-0.4	0.8	-0.3	0.3	-0.8
Bone: trabecular thickness	0.4	0.5	2.1	0.8	-0.4	0.0	-0.3	0.3	1.4
Bone: trabecular tissue density	1.0	1.5	2.2	-1.1	1.2	-0.7	1.3	-1.3	-1.5
Water consumed over 24 hours	0.1	0.1	0.3	-0.2	0.1	-0.6	0.1	-0.1	0.5
Number of responses in last shaping day	0.1	0.1	0.2	0.4	-0.3	0.1	-0.4	0.4	0.3