LOC102551882

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression LOC102551882 0.03 0.02 7.6e-03 0.04 0.01 0.03 0.02 6.1e-05 8.7e-03 2.5e-04 9.8e-04
2 pVTA alternative polyA XM_017597761.2 0.1 0.07 5.2e-03 0.02 0.06 0.06 0.04 3.3e-02 1.0e-03 2.1e-03 8.6e-03
3 pVTA alternative polyA XM_039087578.1 0.11 0.07 3.8e-03 0.03 0.07 0.06 0.04 2.7e-02 5.9e-04 1.4e-03 6.5e-03
4 Brain gene expression LOC102551882 0.11 0.05 3.0e-06 0.07 0.07 0.07 0.07 1.7e-07 6.1e-07 5.2e-07 2.5e-07
5 NAcc alternative polyA XM_017597761.2 0.03 0.02 7.1e-03 0.02 0.02 0.01 0.02 1.1e-03 4.4e-03 6.5e-03 4.5e-03
6 NAcc alternative polyA XM_039087578.1 0.03 0.02 6.0e-03 0.02 0.02 0.02 0.02 8.1e-04 3.7e-03 3.1e-03 3.0e-03
7 PL gene expression LOC102551882 0.06 0.04 7.4e-04 0.04 0.03 0.01 0.03 7.2e-05 1.7e-04 8.9e-03 6.5e-04
8 BLA gene expression LOC102551882 0.11 0.06 3.7e-03 0.03 0.02 0.02 0.01 6.9e-03 3.0e-02 3.4e-02 5.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.10.10.4-0.1-0.50.60.10.2-0.20.2-0.6
Area under the delay curve0.70.82.81.71.1-1.00.40.5-0.50.5-0.6
BMI with tail0.82.76.6-2.6-0.90.8-1.9-1.81.8-1.6-0.9
BMI without tail4.69.515.5-3.71.0-1.1-3.9-3.93.9-3.7-0.8
Body weight2.39.625.0-5.0-1.61.5-3.4-3.23.2-3.2-1.8
Weight adjusted by age1.41.64.1-2.0-1.91.9-0.5-0.50.5-0.6-0.3
Bone surface0.20.30.8-0.9-0.40.4-0.5-0.50.5-0.5-0.7
Bone volume0.10.20.6-0.7-0.40.4-0.3-0.20.2-0.2-0.3
Breakpoint value in progressive ratio session0.40.50.8-0.50.4-0.5-0.9-0.90.9-0.7-0.3
Number of licking bursts0.00.00.10.00.2-0.2-0.0-0.30.3-0.30.1
Context. condit. distance diff. score1.11.31.9-1.00.8-0.8-1.4-1.41.4-1.4-0.7
Locomotion velocity, session 12.52.74.11.2-0.80.92.02.0-2.02.01.6
Locomotion distance, session 10.50.72.30.71.0-0.9-0.5-0.50.5-0.5-1.5
Locomotion velocity, session 20.91.13.92.01.2-1.20.50.7-0.70.7-0.5
Locomotion distance, session 20.81.12.40.41.1-1.1-0.9-0.90.9-0.9-1.6
Locomotion velocity, session 31.41.75.52.30.2-0.11.41.3-1.31.3-0.5
Locomotion distance, session 31.41.66.42.51.0-0.91.00.9-0.90.9-1.1
Stereotopy head waving bouts, day 30.10.20.3-0.0-0.50.50.40.5-0.50.50.0
Stereotopy head waving duration, day 30.10.10.3-0.6-0.20.2-0.3-0.30.3-0.3-0.4
Locomotion velocity, session 70.30.30.91.00.8-0.70.20.0-0.00.0-0.7
Locomotion distance, session 71.41.85.12.32.0-2.00.20.1-0.10.1-0.9
Stereotopy head waving bouts, day 71.31.43.6-1.9-0.20.2-1.4-1.31.3-1.3-0.7
Stereotopy head waving duration, day 70.60.82.4-1.5-0.70.6-0.8-0.80.8-0.8-0.6
Locomotion velocity, session 80.50.64.10.70.3-0.2-0.2-0.10.1-0.1-2.0
Locomotion distance, session 83.34.96.6-0.91.8-1.8-2.5-2.62.6-2.6-2.5
Degree of sensitization distance0.20.20.2-0.50.4-0.4-0.4-0.40.4-0.40.5
Degree of sensitization stereotypy1.01.12.7-1.7-0.20.2-1.2-1.21.2-1.2-0.6
Conditioned locomotion1.61.95.2-2.3-0.60.5-1.5-1.51.5-1.5-0.5
Cocaine response after cond. corrected0.60.71.31.0-0.30.41.11.0-1.01.00.4
Cocaine response after cond. not corrected0.40.51.61.30.2-0.20.90.7-0.70.70.1
Cocaine response before conditioning1.01.22.30.51.5-1.5-1.0-1.01.0-1.0-1.1
Saline control response0.20.30.80.1-0.90.90.50.4-0.40.3-0.1
Bone: connectivity density0.10.21.10.50.1-0.10.00.0-0.00.0-1.0
Bone: cortical apparent density2.12.77.12.70.4-0.41.91.9-1.91.90.7
Bone: cortical area4.16.116.2-4.0-2.92.9-1.8-1.71.7-1.7-2.2
Bone: cortical porosity0.80.92.6-1.6-1.21.2-0.1-0.10.1-0.11.3
Bone: cortical porosity0.80.93.0-1.7-1.21.1-0.3-0.30.3-0.31.1
Bone: cortical thickness3.05.015.1-3.0-3.93.9-0.1-0.00.0-0.0-1.0
Bone: cortical thickness1.21.44.3-1.5-2.12.10.20.2-0.20.20.4
Bone: cortical tissue density2.53.38.12.80.5-0.42.02.1-2.12.10.9
Condit. Reinf. active minus inactive responses0.50.61.8-1.4-1.01.0-0.5-0.50.5-0.5-0.2
Condit. Reinf. active-inactive response ratio0.50.51.3-0.4-1.11.10.10.0-0.00.0-1.1
Condit. Reinf. active responses0.91.14.1-2.0-0.80.7-1.0-0.90.9-0.90.5
Condit. Reinf. inactive responses0.50.61.9-1.10.1-0.2-0.6-0.50.5-0.51.4
Incentive salience index mean0.50.72.0-1.4-0.40.4-0.9-0.80.8-0.8-0.2
Condit. Reinf. lever presses0.50.71.2-0.31.1-1.1-0.9-0.80.8-0.80.0
Condit. Reinf. active minus inactive responses1.21.53.3-1.8-1.41.4-0.8-0.70.7-0.7-1.6
Condit. Reinf. active-inactive response ratio1.61.75.2-2.3-2.02.0-0.4-0.40.4-0.4-0.2
Condit. Reinf. active responses0.71.03.2-1.2-0.70.7-0.9-0.70.7-0.8-1.8
Condit. Reinf. inactive responses0.40.52.40.80.6-0.5-0.3-0.00.0-0.1-1.5
Condit. Reinf. lever presses0.30.40.8-0.40.4-0.4-0.9-0.70.7-0.7-0.7
Condit. Reinf. lever reinforcers received1.01.43.2-1.4-0.40.3-1.3-1.11.1-1.2-1.8
Conditioned reinforcement - actives0.20.20.60.40.8-0.8-0.1-0.20.2-0.10.2
Conditioned reinforcement - inactives0.10.10.30.40.4-0.40.3-0.20.20.10.5
Conditioned locomotion0.50.61.60.11.2-1.2-0.8-0.60.6-0.9-0.2
Patch foraging indifference point 0 sec0.20.30.60.8-0.10.10.60.6-0.60.6-0.1
Patch foraging indifference point AUC0.30.31.7-0.60.1-0.1-0.40.2-0.20.11.3
Delay disc. indifference point, 0s delay0.20.20.30.4-0.50.50.50.5-0.50.4-0.5
Delay disc. indifference point, 16s delay1.81.84.71.32.2-2.1-0.5-0.70.7-0.6-1.3
Delay disc. indifference point, 2s delay0.10.10.20.30.5-0.5-0.3-0.00.0-0.2-0.1
Delay disc. indifference point, 24s delay1.01.03.41.80.9-0.80.80.7-0.70.9-0.8
Delay disc. indifference point, 4s delay2.02.15.02.2-0.20.31.51.8-1.81.8-0.4
Delay disc. indifference point, 8s delay0.80.81.91.4-0.10.11.11.1-1.11.1-0.1
Indifference point function ln k0.40.62.81.10.2-0.10.60.2-0.20.5-1.7
Indifference point function log k0.40.62.81.10.2-0.10.60.2-0.20.5-1.7
Patch foraging total patch changes 0 sec0.20.30.70.8-0.10.10.60.6-0.60.6-0.2
Patch foraging total patch changes 12 sec0.50.63.20.20.1-0.10.20.8-0.80.71.8
Patch foraging total patch changes 18 sec0.10.20.40.60.5-0.5-0.10.4-0.40.2-0.4
Patch foraging total patch changes 24 sec0.20.30.70.2-0.40.40.20.8-0.80.50.2
Patch foraging total patch changes 6 sec0.20.31.4-0.1-0.40.40.20.5-0.50.51.2
Patch foraging time to switch 0 sec0.10.10.40.20.6-0.6-0.2-0.30.3-0.1-0.1
Patch foraging water rate 0 sec0.00.00.20.4-0.00.00.20.1-0.1-0.0-0.1
Patch foraging water rate 12 sec0.00.00.20.1-0.10.10.10.0-0.0-0.1-0.5
Patch foraging water rate 18 sec0.81.13.8-0.40.2-0.2-0.9-1.11.1-1.1-2.0
Patch foraging water rate 24 sec1.11.65.5-0.60.1-0.1-1.1-1.31.3-1.4-2.3
Patch foraging water rate 6 sec0.10.20.90.50.3-0.30.1-0.00.0-0.3-0.9
Seeking ratio, delayed vs. immediate footshock0.30.30.9-0.4-0.91.00.40.3-0.30.30.2
Distance traveled before self-admin0.60.61.10.4-1.01.00.80.8-0.80.9-0.1
Distance traveled after self-admin0.70.72.20.01.5-1.5-0.5-0.50.5-0.20.8
Extensor digitorum longus weight0.83.35.2-2.30.6-0.6-2.2-2.22.2-2.1-1.2
Bone: elastic displacement0.60.71.9-0.5-1.41.40.50.6-0.60.60.3
Bone: elastic work4.15.315.4-2.6-3.93.90.81.0-1.01.01.1
Bone: endosteal estimation2.45.37.9-2.01.4-1.4-2.8-2.82.8-2.8-2.0
Bone: endosteal perimeter0.81.73.7-1.9-0.60.6-1.3-1.31.3-1.3-1.6
Epididymis fat weight0.92.23.7-1.90.4-0.5-1.9-1.81.8-1.7-0.3
Delta time in closed arm before/after self-admin0.50.50.80.3-0.50.50.80.9-0.90.80.4
Delta time in open arm before/after self-admin0.30.31.31.10.7-0.70.30.1-0.10.10.2
Diff in mean of infusions in LGA sessions0.20.20.60.50.8-0.8-0.1-0.00.0-0.1-0.1
Delay discount exponential model param1.11.14.1-2.0-1.01.0-0.7-0.80.8-0.90.4
Extinction: sum of active levers before priming1.21.21.81.1-0.70.71.31.3-1.31.30.9
Active lever presses in extinction session 60.20.20.90.90.3-0.30.20.3-0.30.2-0.6
Bone: final force3.55.715.8-4.0-2.42.3-2.0-1.91.9-1.9-2.0
Bone: final moment3.86.117.7-4.2-2.82.7-1.9-1.81.8-1.8-1.8
Food consumed during 24 hour testing period0.10.10.3-0.3-0.40.40.20.2-0.20.20.6
Glucose1.31.92.80.9-0.90.91.61.7-1.71.61.4
Heart weight1.52.16.2-2.5-0.90.8-1.4-1.61.6-1.5-0.2
Delay discount hyperbolic model param1.11.14.2-2.0-1.00.9-0.7-0.90.9-0.90.4
Intermittent access intake day 1-15 change0.30.31.11.10.5-0.50.40.2-0.20.50.4
Intermittent access intake escalation0.50.51.30.81.2-1.2-0.1-0.40.4-0.10.3
Intermittent access intake escalation 20.20.20.70.50.3-0.30.30.0-0.00.30.8
Intermitt. access day 1 inactive lever presses0.00.00.1-0.1-0.30.30.30.1-0.10.10.2
Intermitt. access day 15 inactive lever presses0.40.42.20.50.5-0.5-0.2-0.40.4-0.3-1.5
Intermitt. access escalation Index0.20.20.7-0.8-0.50.5-0.3-0.00.0-0.00.1
Intermittent access day 1 total infusions0.70.91.7-1.30.1-0.2-1.2-1.11.1-1.2-0.1
Intermittent access day 15 total infusions0.30.30.5-0.10.7-0.7-0.6-0.70.7-0.50.2
Intermittent access terminal intake (last 3 days)0.10.10.4-0.10.3-0.3-0.2-0.20.2-0.10.6
Intermittent access total infusions0.20.20.4-0.40.4-0.4-0.6-0.50.5-0.40.0
Intermittent access day 1 locomotion0.40.40.9-0.10.8-0.8-0.9-0.40.4-0.9-0.6
Intermittent access day 15 total locomotion0.10.10.20.30.3-0.3-0.3-0.20.2-0.4-0.5
Intermittent access total locomotion0.20.30.60.30.8-0.7-0.6-0.20.2-0.5-0.5
Intermittent access standard deviation1.21.34.92.20.7-0.61.20.9-0.91.20.4
Left kidney weight0.92.57.6-2.8-1.51.5-1.4-1.21.2-1.2-1.4
Right kidney weight0.51.43.5-1.9-1.01.0-1.1-0.90.9-0.7-1.5
Cocaine induced anxiety2.63.06.0-0.3-2.52.51.31.5-1.51.51.6
Post-drug Anxiety1.61.82.70.8-1.31.31.41.7-1.71.70.6
Baseline Anxiety1.61.75.31.61.8-1.7-0.0-0.10.1-0.1-2.3
Tail length2.67.812.4-3.50.8-0.9-3.4-3.53.5-3.5-0.7
Length with tail1.03.510.2-3.2-1.00.9-2.0-1.91.9-2.0-0.9
Length without tail0.61.33.7-0.6-1.91.90.70.9-0.90.8-0.5
Times rat made contact with spout1.51.77.5-0.5-1.11.11.10.9-0.90.92.7
Lifetime Intake0.10.10.20.10.4-0.4-0.1-0.10.1-0.10.5
Liver weight, left0.20.30.4-0.60.0-0.1-0.6-0.60.6-0.60.5
Liver weight, right1.52.65.6-2.4-0.20.1-2.0-1.81.8-2.0-0.5
Locomotor activity0.30.41.10.41.1-1.1-0.3-0.50.5-0.6-0.3
Locomotor testing distance0.50.81.8-0.11.0-1.0-0.7-0.90.9-0.9-1.3
Locomotor testing rearing0.40.71.91.31.4-1.30.10.1-0.10.10.0
Locomotion in novel chamber0.10.21.1-0.3-0.30.3-0.2-0.00.0-0.2-1.0
Locomotion in novel chamber post-restriction0.91.13.4-1.9-0.60.5-1.2-1.01.0-1.20.3
Fecal boli incidents, locomotor time 11.11.21.8-0.61.2-1.2-1.3-1.21.2-1.3-0.1
Change in fecal boli incidents, locomotor task2.42.23.51.40.1-0.01.51.9-1.91.81.8
Time >=10cm from walls, locomotor time 10.20.21.40.60.3-0.3-0.00.1-0.1-0.2-1.2
Bouts of movement, locomotor time 10.10.10.40.30.0-0.00.40.4-0.40.30.6
Total resting periods, locomotor time 10.30.40.60.70.0-0.00.70.7-0.70.70.8
Rest time, locomotor task time 10.20.20.6-0.40.4-0.4-0.6-0.20.2-0.30.8
Distance moved, locomotor task time 10.30.31.21.10.4-0.30.70.2-0.20.3-0.6
Vertical activity count, locomotor time 10.20.20.90.10.3-0.3-0.2-0.50.5-0.4-1.0
Time >=10cm from walls, locomotor time 20.40.41.3-0.3-1.11.10.20.1-0.10.0-0.6
Bouts of movement, locomotor time 20.10.10.30.50.5-0.50.1-0.10.1-0.2-0.5
Total resting periods, locomotor time 20.30.30.50.10.7-0.7-0.4-0.50.5-0.6-0.7
Rest time, locomotor task time 20.50.61.0-0.90.7-0.7-1.0-0.70.7-0.80.5
Distance moved, locomotor task time 20.40.40.91.0-0.20.31.00.7-0.70.8-0.0
Vertical activity count, locomotor time 21.11.21.8-0.60.7-0.7-1.1-1.31.3-1.2-1.3
Light reinforcement 10.30.51.8-1.3-0.80.8-0.30.2-0.2-0.10.9
Light reinforcement 20.60.83.2-1.8-0.60.6-0.7-0.70.7-0.60.5
Bone: marrow area2.45.37.8-1.91.4-1.4-2.8-2.72.7-2.7-2.0
Bone: maximum diameter1.73.26.6-2.6-1.21.2-1.7-1.61.6-1.6-2.3
Bone: maximum force4.68.022.3-4.7-2.32.2-2.7-2.52.5-2.5-2.2
Bone: maximum moment4.88.324.9-5.0-2.72.6-2.5-2.42.4-2.4-2.0
Mean time between licks in bursts0.60.82.81.71.0-0.90.70.6-0.60.6-0.2
Mean num. licks in bursts0.40.51.5-0.4-0.80.70.40.6-0.60.61.2
Cd content in liver0.30.41.11.00.9-0.90.1-0.00.0-0.0-0.4
Co content in liver0.20.20.40.30.5-0.50.0-0.40.4-0.3-0.6
Cu content in liver1.01.22.00.7-0.90.91.41.2-1.21.20.9
Fe content in liver1.01.22.20.81.5-1.5-0.6-0.80.8-0.8-1.4
K content in liver0.10.10.30.00.5-0.5-0.0-0.40.4-0.30.2
Mg content in liver1.01.03.11.01.8-1.8-0.2-0.60.6-0.5-0.0
Mn content in liver0.10.10.20.3-0.10.10.30.2-0.20.30.5
Na content in liver0.30.41.11.00.1-0.10.70.7-0.70.6-0.1
Rb content in liver0.20.30.5-0.40.1-0.1-0.6-0.70.7-0.6-0.6
Se content in liver0.60.71.11.00.0-0.00.91.0-1.00.91.1
Sr content in liver2.82.53.50.7-1.51.51.91.9-1.91.91.2
Zn content in liver0.30.30.4-0.10.6-0.6-0.5-0.60.6-0.5-0.7
Bone: minimum diameter1.42.56.9-2.6-2.22.1-0.8-0.80.8-0.8-1.3
Time in familiar zone, hab. session 10.30.30.9-0.0-0.40.40.50.4-0.40.40.9
Time in novel zone, hab. session 10.10.10.20.4-0.00.00.30.5-0.50.50.2
Total zone transitions, hab. session 10.10.10.30.40.6-0.6-0.2-0.20.2-0.2-0.1
Total locomotion distance, hab. session 10.60.91.5-0.80.5-0.5-1.1-1.21.2-1.2-0.4
Locomotion velocity, hab. session 11.11.52.6-1.10.7-0.7-1.5-1.61.6-1.6-0.6
Time in familiar zone, hab. session 20.10.10.40.30.6-0.60.1-0.20.2-0.20.4
Time in novel zone, hab. session 20.20.20.30.2-0.40.40.10.4-0.40.4-0.6
Total zone transitions, hab. session 20.81.01.5-0.50.8-0.8-1.1-1.21.2-1.2-0.9
Total locomotion distance, hab. session 21.52.03.2-1.40.7-0.7-1.6-1.81.8-1.8-0.6
Locomotion velocity, hab. session 21.62.13.5-1.60.5-0.6-1.7-1.91.9-1.9-0.7
Novel to familiar place preference ratio1.61.74.5-1.2-2.12.10.60.8-0.80.80.9
Novelty place preference1.81.95.0-1.3-2.22.20.70.8-0.80.80.8
Time in novel zone, NPP test1.51.54.1-1.2-2.02.00.60.8-0.80.80.8
Total zone transitions, NPP test1.72.53.40.11.7-1.7-1.6-1.61.6-1.6-1.8
Total locomotion distance, NPP test2.83.85.4-0.91.9-1.9-2.2-2.32.3-2.3-1.3
Locomotion velocity, NPP test2.13.04.4-1.01.4-1.5-2.0-2.12.1-2.1-1.2
Intraocular pressure1.52.23.5-1.50.6-0.6-1.9-1.71.7-1.8-1.3
Delta distance traveled before/after self-admin0.91.03.40.71.8-1.8-0.2-0.40.4-0.10.8
Delta ambulatory time before/after self-admin1.11.24.10.72.0-2.0-0.2-0.20.2-0.10.9
Parametrial fat weight0.91.85.6-2.1-0.1-0.0-1.1-0.90.9-1.02.4
Pavlov. Cond. lever latency1.92.44.80.41.7-1.7-1.4-1.41.4-1.5-2.2
Pavlov. Cond. magazine entry latency1.72.23.8-0.6-1.91.91.21.4-1.41.41.7
Pavlov. Cond. change in total contacts1.01.02.7-0.1-0.90.90.91.0-1.01.01.6
Pavlov. Cond. index score1.41.73.4-1.2-1.81.80.70.8-0.80.81.8
Pavlov. Cond. latency score1.51.94.0-1.1-1.81.80.81.0-1.01.02.0
Pavlov. Cond. lever contacts0.50.61.9-0.5-0.80.80.50.5-0.50.61.4
Pavlov. Cond. magazine entry number2.02.54.50.82.0-2.0-1.1-1.31.3-1.3-2.1
Pavlov. Cond. intertrial magazine entries0.60.71.2-0.90.5-0.5-1.0-1.11.1-1.1-0.1
Pavlov. Cond. lever-magazine prob. diff.1.41.83.8-1.0-2.01.90.81.0-1.01.01.5
Pavlov. Cond. response bias1.61.93.6-0.7-1.81.71.01.2-1.21.21.9
Pavlov. Cond. lever latency1.21.62.71.5-0.40.51.61.5-1.51.50.7
Pavlov. Cond. magazine entry latency1.92.25.60.52.4-2.4-1.4-1.21.2-1.2-0.6
Pavlov. Cond. change in total contacts1.11.52.5-0.31.1-1.1-1.3-1.31.3-1.3-1.6
Pavlov. Cond. index score1.51.92.7-0.51.6-1.6-1.7-1.51.5-1.5-0.7
Pavlov. Cond. latency score1.62.03.0-0.61.5-1.5-1.7-1.51.5-1.6-0.7
Pavlov. Cond. lever contacts1.31.83.1-1.50.5-0.5-1.8-1.61.6-1.6-0.8
Pavlov. Cond. magazine entry number2.02.56.3-0.6-2.52.51.41.2-1.21.20.6
Pavlov. Cond. intertrial magazine entries0.40.51.2-1.0-1.11.1-0.3-0.20.2-0.1-0.6
Pavlov. Cond. lever-magazine prob. diff.1.52.03.1-0.31.7-1.8-1.6-1.41.4-1.5-0.6
Pavlov. Cond. response bias1.11.52.4-0.81.2-1.2-1.6-1.41.4-1.4-0.6
Time in closed arm before self-admin0.00.00.2-0.10.1-0.1-0.40.0-0.0-0.1-0.4
Time in closed arm after self-admin1.01.02.10.9-0.30.41.01.4-1.41.20.7
Time in open arm before self-admin0.30.41.1-0.8-1.01.00.20.0-0.00.0-0.0
Time in open arm after self-admin0.10.10.10.3-0.10.10.2-0.30.3-0.2-0.4
Bone: periosteal estimation3.26.514.0-3.7-1.11.0-2.7-2.72.7-2.7-2.7
Bone: periosteal perimeter2.13.510.0-3.2-2.62.6-0.9-0.80.8-0.8-1.2
Bone: post-yield work0.71.03.3-0.60.2-0.2-1.0-1.01.0-1.0-1.8
Progressive ratio test 1 active lever presses0.20.20.4-0.30.2-0.2-0.5-0.50.5-0.7-0.4
Progressive ratio test 1 breakpoint0.30.30.6-0.6-0.00.0-0.6-0.60.6-0.8-0.3
Progressive ratio test 1 inactive lever presses0.00.00.1-0.0-0.30.30.20.1-0.1-0.1-0.2
Progressive ratio test 2 active lever presses0.30.30.6-0.60.3-0.3-0.7-0.70.7-0.80.1
Progressive ratio test 2 breakpoint0.40.50.8-0.70.4-0.4-0.9-0.80.8-0.9-0.1
Progressive ratio test 2 inactive lever presses0.10.10.20.3-0.40.40.40.1-0.10.2-0.3
Incentive Sensitization - Responses0.30.31.1-1.1-0.10.1-0.6-0.50.5-0.50.6
Incentive Sensitization - Breakpoint0.30.31.1-1.1-0.20.2-0.5-0.40.4-0.40.5
Sum of active levers in priming session hrs 5-60.40.41.8-0.70.1-0.2-0.5-0.30.3-0.41.4
Progressive ratio1.51.82.4-0.81.1-1.1-1.5-1.51.5-1.5-1.3
Food seeking constrained by brief footshock0.40.50.80.9-0.10.10.70.9-0.90.80.7
Seeking ratio, punishment vs. effort1.01.21.90.9-0.80.81.21.4-1.41.30.9
Retroperitoneal fat weight2.47.917.8-4.2-0.0-0.1-3.4-3.33.3-3.4-0.2
Reaction time number correct1.52.25.3-0.01.4-1.4-1.3-1.51.5-1.3-2.3
Reaction time mean minus median0.20.31.50.40.4-0.50.30.3-0.30.21.2
Reaction time mean minus median AUC0.00.10.20.20.2-0.20.10.2-0.20.10.4
Reaction time num false alarms0.20.30.9-0.9-0.30.3-0.3-0.50.5-0.5-0.4
Reaction time num false alarms AUC0.10.20.3-0.50.2-0.2-0.2-0.50.5-0.4-0.4
Reaction time trials correct on left1.52.25.3-0.01.4-1.4-1.3-1.51.5-1.3-2.3
Reaction time trials on left1.62.35.60.01.5-1.5-1.3-1.51.5-1.3-2.4
Reaction time mean0.10.20.4-0.70.0-0.0-0.3-0.50.5-0.40.6
Reaction time mean AUC0.30.40.8-0.70.4-0.4-0.7-0.90.9-0.90.0
Median of all reaction times0.10.10.3-0.6-0.10.1-0.2-0.40.4-0.30.3
Reaction time omissions0.20.30.80.80.9-0.90.1-0.20.2-0.00.2
Reaction time false alarm rate0.20.30.7-0.4-0.60.60.60.3-0.30.30.8
Reaction time premature initiation rate0.30.40.80.90.3-0.30.80.6-0.60.80.7
Reaction time premature initiations0.40.51.40.71.2-1.2-0.2-0.50.5-0.2-0.7
Std. dev. reaction times0.20.20.70.40.8-0.8-0.1-0.10.1-0.30.4
Reaction time trials completed1.62.35.60.01.5-1.5-1.3-1.51.5-1.3-2.4
Reaction time trials AUC1.42.15.3-0.01.4-1.3-1.3-1.51.5-1.3-2.3
Run reversals in cocaine runway, females0.40.40.6-0.40.7-0.7-0.8-0.50.5-0.7-0.5
Run reversals in cocaine runway, males0.50.52.1-0.9-0.80.70.10.1-0.10.31.4
Latency to leave start box in cocaine runway1.81.93.1-1.31.3-1.4-1.8-1.51.5-1.6-0.2
Latency to leave start box in cocaine runway, F3.03.35.4-1.61.6-1.6-2.3-2.02.0-2.2-1.0
Latency to leave start box in cocaine runway, M0.30.31.2-0.70.3-0.4-0.4-0.40.4-0.31.1
Std. dev. time between licks in bursts1.51.83.7-0.11.3-1.3-1.4-1.31.3-1.3-1.9
Total sessions with >9 infusions0.30.30.50.20.7-0.7-0.5-0.50.5-0.6-0.7
Short access day 1 total inactive lever presses1.11.21.7-1.10.9-1.0-1.3-1.21.2-1.3-0.4
Short access day 10 total inactive lever presses0.30.30.8-0.5-0.90.90.50.2-0.20.20.4
Short access day 1 total infusions0.70.81.51.20.1-0.11.11.1-1.11.00.3
Short access day 10 total infusions0.00.10.3-0.20.1-0.2-0.10.1-0.10.00.5
Short access total infusions0.40.41.00.70.00.00.70.7-0.70.61.0
Short access day 1 locomotion1.01.01.90.8-0.80.81.11.4-1.41.10.2
Short access day 10 total locomotion1.92.13.71.6-0.30.41.61.9-1.91.51.3
Short access total locomotion1.01.12.11.2-0.40.51.21.5-1.51.00.5
One hour access (0.3 mA shock)0.40.40.7-0.80.2-0.2-0.8-0.80.8-0.60.4
Compulsive drug intake0.10.10.2-0.4-0.40.4-0.2-0.40.4-0.4-0.3
One hour access (shock baseline)0.50.61.1-1.00.6-0.6-1.0-0.90.9-0.70.2
Social response proportion0.50.52.60.80.7-0.70.1-0.30.3-0.1-1.6
Social responses0.40.51.20.9-0.20.20.80.7-0.70.6-1.1
Social time0.20.31.6-0.1-0.20.20.0-0.40.4-0.4-1.3
Soleus weight0.30.93.2-1.8-1.31.3-0.3-0.10.1-0.10.5
Bone: stiffness2.94.68.4-2.9-0.30.3-2.4-2.52.5-2.5-2.0
Tibialis anterior weight0.20.82.2-1.50.1-0.2-1.1-1.01.0-0.90.1
Time to tail flick, vehicle, before self-admin0.10.10.20.50.3-0.3-0.20.3-0.30.3-0.2
Time to tail flick, vehicle, after self-admin0.10.10.2-0.00.4-0.4-0.3-0.10.1-0.2-0.5
Time to tail flick, test, before self-admin0.80.82.31.11.5-1.5-0.2-0.10.1-0.30.7
Time to tail flick, test, after self-admin1.21.23.31.80.8-0.80.91.3-1.31.10.3
Delta time to tail flick, vehicle, before/after SA0.50.50.7-0.80.6-0.7-0.6-0.80.8-0.90.6
Delta time to tail flick, test, before/after SA0.90.81.4-0.0-1.01.10.91.0-1.01.20.1
Tibia length4.412.438.1-6.2-5.15.0-1.5-1.41.4-1.4-1.1
Ambulatory time before self-admin1.01.01.90.4-1.41.40.91.0-1.01.1-0.3
Ambulatory time after self-admin0.20.20.50.40.7-0.70.0-0.10.10.30.4
Bone: tissue strength2.82.74.8-1.8-0.10.1-1.8-1.91.9-1.9-2.2
Total heroin consumption0.80.92.0-0.9-0.50.5-0.9-1.01.0-1.0-1.4
Bone: trabecular number0.20.30.50.3-0.50.50.70.7-0.70.70.4
Bone: trabecular spacing3.44.45.8-0.71.9-1.9-2.4-2.42.4-2.4-2.3
Bone: trabecular thickness2.63.15.1-0.6-2.32.31.71.7-1.71.71.8
Bone: trabecular tissue density0.70.91.70.61.3-1.3-0.8-0.80.8-0.8-1.1
Water consumed over 24 hours1.51.82.90.7-1.11.11.71.5-1.51.51.4
Number of responses in last shaping day0.10.10.20.1-0.50.50.00.1-0.1-0.1-0.2