Hub : Genes

LOC102549592

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	LOC102549592	0.02	0.02	5.1e-03	0.01	0.01	0	0	3.1e-02	1.4e-02	8.1e-02	8.2e-02
2	Brain	gene expression	LOC102549592	0.09	0.05	4.1e-08	0.06	0.08	0.07	0.07	4.3e-06	8.5e-08	5.3e-07	1.7e-07
3	Brain	intron excision ratio	chr3_116408569_116411914	0.03	0.02	7.8e-03	0.01	0.01	0.01	0	7.9e-02	3.6e-02	6.6e-02	1.0e-01
4	NAcc	gene expression	LOC102549592	0.06	0.04	1.4e-07	0.05	0.06	0.05	0.06	2.9e-06	2.0e-07	6.7e-07	3.2e-07
5	Brain	intron excision ratio	chr3_116408104_116408408	0.03	0.02	4.6e-03	0.02	0.01	0.02	0.01	2.9e-03	1.7e-02	1.1e-02	1.7e-02
6	PL	gene expression	LOC102549592	0.02	0.02	6.4e-03	0.02	0.02	0.01	0.01	4.3e-03	5.8e-03	7.9e-03	8.6e-03
7	Adipose	intron excision ratio	chr3_116406947_116408408	0.04	0.03	5.4e-04	0.02	0.03	0.05	0.02	9.8e-04	7.3e-04	1.2e-06	1.1e-03
8	Eye	gene expression	LOC102549592	0.57	0.23	3.7e-03	0.03	0.04	0.06	0.08	9.9e-02	8.0e-02	5.2e-02	2.4e-02
9	BLA	isoform ratio	XR_005502444.1	0.09	0.07	1.7e-03	0.01	0.03	0.04	0.03	7.3e-02	1.2e-02	3.1e-03	9.1e-03
10	pVTA	gene expression	LOC102549592	0.1	0.07	1.2e-03	0.06	0.06	0.07	0.06	1.2e-03	1.1e-03	7.2e-04	2.0e-03
11	Eye	alternative TSS	XR_005502444.1	0.58	0.25	2.0e-03	0.15	0.04	0.04	0.1	3.0e-03	9.9e-02	8.7e-02	1.1e-02
12	Eye	alternative TSS	XR_005502445.1	0.63	0.23	6.0e-04	0.16	0.03	0.05	0.11	2.1e-03	1.1e-01	6.5e-02	9.8e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bone: apparent density	1.2	2.1	4.0	-2.0	-2.0	-1.9	-1.8	-1.8	1.8	0.1	-1.2	0.6	1.2	-0.6	0.6
Area under the delay curve	0.3	0.3	1.1	0.7	0.6	0.7	0.6	0.5	-1.0	0.3	0.2	-0.2	-0.8	0.1	-0.1
BMI with tail	0.7	2.3	4.8	-1.5	-1.6	-1.6	-1.8	-2.2	0.9	0.2	0.9	2.2	0.8	1.6	-1.6
BMI without tail	2.2	4.5	10.9	-2.2	-2.3	-2.4	-2.6	-3.3	1.5	1.1	1.1	2.6	0.9	2.0	-2.0
Body weight	3.1	13.0	27.5	-4.5	-4.6	-4.7	-4.8	-5.2	3.3	-1.9	0.2	3.9	2.3	1.7	-1.7
Weight adjusted by age	3.1	3.5	6.7	-2.6	-2.6	-2.4	-2.3	-2.0	2.2	-0.5	-1.8	0.4	1.8	-1.0	1.0
Bone surface	1.0	1.7	3.0	-1.7	-1.7	-1.6	-1.6	-1.3	1.6	-1.0	-1.2	0.4	1.2	-0.7	0.7
Bone volume	1.0	1.8	3.2	-1.8	-1.8	-1.7	-1.6	-1.4	1.7	-0.4	-1.3	0.3	1.2	-0.8	0.8
Breakpoint value in progressive ratio session	1.2	1.3	2.4	-1.0	-1.0	-1.2	-1.3	-1.1	1.3	1.6	0.7	1.4	0.5	1.1	-1.1
Number of licking bursts	0.5	0.6	2.5	0.5	0.4	0.5	0.5	-0.9	-0.9	-0.2	0.9	0.0	-1.6	0.7	-0.7
Context. condit. distance diff. score	1.1	1.4	2.5	-1.3	-1.3	-1.1	-0.9	-1.1	1.3	-1.3	-1.6	-0.6	-0.0	-1.4	1.4
Locomotion velocity, session 1	0.2	0.2	1.3	-0.2	-0.1	-0.2	-0.2	0.6	0.6	-0.1	-0.4	0.1	1.1	-0.3	0.3
Locomotion distance, session 1	1.2	1.5	2.6	-1.4	-1.4	-1.3	-1.2	-0.6	1.5	-0.9	-1.6	-0.2	1.3	-1.3	1.3
Locomotion velocity, session 2	0.0	0.0	0.2	0.2	0.2	0.2	0.1	0.4	-0.1	-0.4	0.1	0.1	0.2	0.1	-0.1
Locomotion distance, session 2	2.4	3.3	5.7	-2.4	-2.3	-2.3	-2.1	-1.3	2.4	-0.5	-1.9	0.5	2.2	-1.2	1.2
Locomotion velocity, session 3	0.7	0.9	2.6	-0.5	-0.5	-0.6	-0.8	-1.1	0.0	-0.4	1.1	1.6	0.0	1.3	-1.3
Locomotion distance, session 3	4.1	4.4	9.7	-2.2	-2.3	-2.4	-2.6	-3.1	1.3	-0.1	1.0	3.1	1.1	1.9	-1.9
Stereotopy head waving bouts, day 3	1.7	2.1	5.3	0.5	0.7	0.7	1.0	1.9	0.3	-0.1	-1.9	-2.2	-0.1	-2.3	2.3
Stereotopy head waving duration, day 3	0.9	1.1	2.9	0.9	1.0	1.0	1.1	1.7	-0.1	0.3	-0.8	-1.5	-0.4	-1.2	1.2
Locomotion velocity, session 7	1.4	1.5	8.4	-1.3	-1.3	-1.2	-1.2	-1.6	0.8	-2.9	-0.4	0.6	-0.0	-0.0	0.0
Locomotion distance, session 7	2.4	3.1	5.0	-2.2	-2.2	-2.1	-1.9	-2.1	2.1	-2.0	-1.7	0.2	1.1	-1.2	1.2
Stereotopy head waving bouts, day 7	0.2	0.3	0.6	0.1	0.1	0.0	-0.1	-0.0	-0.2	0.8	0.7	0.8	-0.1	0.8	-0.8
Stereotopy head waving duration, day 7	0.5	0.6	1.5	0.7	0.7	0.6	0.4	0.5	-0.7	0.5	1.2	0.7	-0.3	1.1	-1.1
Locomotion velocity, session 8	0.9	1.0	2.7	-1.1	-1.1	-1.0	-1.0	-0.6	1.1	-1.6	-1.0	0.1	1.1	-0.7	0.7
Locomotion distance, session 8	4.4	6.4	10.7	-3.3	-3.2	-3.1	-2.8	-2.4	3.2	-2.0	-2.7	0.3	2.0	-1.9	1.9
Degree of sensitization distance	2.1	2.1	5.6	0.1	0.2	0.4	0.7	0.9	0.5	-1.5	-2.1	-2.3	-0.3	-2.4	2.4
Degree of sensitization stereotypy	1.3	1.4	3.6	-0.3	-0.4	-0.5	-0.7	-1.1	-0.1	1.3	1.6	1.9	0.3	1.9	-1.9
Conditioned locomotion	2.5	2.9	5.5	-2.2	-2.1	-2.1	-2.0	-1.1	2.3	-1.3	-1.7	0.5	1.9	-1.1	1.1
Cocaine response after cond. corrected	0.1	0.2	0.3	0.1	0.1	0.1	0.2	0.5	0.1	-0.3	-0.6	-0.5	0.2	-0.6	0.6
Cocaine response after cond. not corrected	0.2	0.2	0.6	0.2	0.3	0.3	0.3	0.8	0.0	0.4	-0.4	-0.4	0.5	-0.5	0.5
Cocaine response before conditioning	0.2	0.2	1.5	0.4	0.4	0.3	0.3	0.5	-0.3	1.2	0.4	0.2	0.4	0.3	-0.3
Saline control response	2.6	3.4	6.5	-2.5	-2.5	-2.5	-2.5	-2.5	1.9	-0.8	-0.4	1.7	1.1	0.3	-0.3
Bone: connectivity density	0.7	1.1	2.0	-1.4	-1.4	-1.3	-1.3	-1.2	1.3	-0.5	-0.9	0.4	0.9	-0.4	0.4
Bone: cortical apparent density	0.7	1.0	6.8	-0.2	-0.2	-0.3	-0.4	-0.2	0.1	2.6	0.9	1.1	0.5	1.1	-1.1
Bone: cortical area	1.8	2.7	5.0	-2.2	-2.2	-2.2	-2.2	-2.0	1.7	0.2	-0.4	1.5	1.6	0.2	-0.2
Bone: cortical porosity	1.7	1.8	4.7	1.3	1.3	1.1	0.9	0.5	-1.4	0.5	2.2	1.0	-0.7	2.0	-2.0
Bone: cortical porosity	1.5	1.7	5.0	0.8	0.8	0.6	0.3	-0.1	-1.1	0.6	2.2	1.5	-0.5	2.2	-2.2
Bone: cortical thickness	0.9	1.5	3.7	-1.2	-1.2	-1.3	-1.4	-0.9	1.3	1.9	-0.0	1.3	1.7	0.5	-0.5
Bone: cortical thickness	0.3	0.3	1.7	-0.3	-0.3	-0.4	-0.5	-0.5	0.1	1.3	0.4	0.8	0.1	0.6	-0.6
Bone: cortical tissue density	0.6	0.8	6.2	-0.0	-0.0	-0.2	-0.3	-0.1	0.0	2.5	0.9	0.9	0.4	1.0	-1.0
Condit. Reinf. active minus inactive responses	0.5	0.6	1.3	-0.7	-0.7	-0.8	-0.9	-0.7	0.8	0.8	0.2	1.0	1.1	0.5	-0.5
Condit. Reinf. active-inactive response ratio	0.9	0.9	2.4	-1.2	-1.1	-1.2	-1.2	-0.8	1.3	0.5	-0.6	0.6	1.6	-0.2	0.2
Condit. Reinf. active responses	0.2	0.3	0.7	-0.4	-0.4	-0.5	-0.5	-0.4	0.5	0.9	0.2	0.6	0.7	0.3	-0.3
Condit. Reinf. inactive responses	0.1	0.1	0.3	0.0	0.1	0.0	0.1	0.4	0.1	0.1	-0.4	-0.4	0.2	-0.5	0.5
Incentive salience index mean	0.3	0.4	1.2	-0.7	-0.7	-0.7	-0.7	-0.5	0.7	0.7	-0.5	0.4	1.1	-0.2	0.2
Condit. Reinf. lever presses	0.1	0.1	0.3	-0.3	-0.3	-0.2	-0.2	-0.3	0.1	0.5	-0.4	0.0	0.4	-0.2	0.2
Condit. Reinf. active minus inactive responses	2.4	3.0	5.8	-2.4	-2.4	-2.4	-2.3	-1.9	2.0	-0.6	-1.2	1.0	1.7	-0.5	0.5
Condit. Reinf. active-inactive response ratio	2.3	2.4	4.5	-2.1	-2.1	-2.1	-2.0	-2.1	1.6	-1.1	-0.8	1.0	1.2	-0.2	0.2
Condit. Reinf. active responses	3.0	4.2	8.3	-2.8	-2.8	-2.9	-2.8	-2.3	2.3	-0.3	-1.0	1.6	1.9	-0.2	0.2
Condit. Reinf. inactive responses	0.5	0.6	1.3	-1.1	-1.1	-1.1	-1.1	-0.6	1.0	0.3	-0.6	0.5	0.8	-0.3	0.3
Condit. Reinf. lever presses	0.8	1.1	2.3	-1.3	-1.4	-1.4	-1.4	-1.5	0.7	0.8	0.1	1.2	0.7	0.5	-0.5
Condit. Reinf. lever reinforcers received	2.5	3.5	6.8	-2.6	-2.6	-2.6	-2.5	-2.1	2.1	-0.2	-1.1	1.3	1.7	-0.4	0.4
Conditioned reinforcement - actives	0.6	0.6	3.0	-0.6	-0.7	-0.6	-0.7	-1.1	0.4	1.7	-0.0	0.7	-0.1	0.3	-0.3
Conditioned reinforcement - inactives	3.2	3.6	7.1	-2.2	-2.2	-2.0	-1.8	-1.2	1.8	-1.4	-2.7	-0.2	2.1	-2.0	2.0
Conditioned locomotion	0.7	0.8	8.1	-0.3	-0.4	-0.2	-0.3	-0.8	0.2	2.9	-0.1	0.3	-0.3	0.1	-0.1
Patch foraging indifference point 0 sec	0.7	1.2	3.2	-0.9	-0.8	-0.7	-0.5	0.1	1.0	-0.4	-1.8	-0.9	1.0	-1.7	1.7
Patch foraging indifference point AUC	0.5	0.6	3.1	-0.7	-0.7	-0.7	-0.7	-0.6	0.9	-1.8	-0.1	0.3	1.1	0.0	-0.0
Delay disc. indifference point, 0s delay	2.8	3.1	5.5	2.3	2.3	2.3	2.3	2.3	-1.9	1.5	0.7	-1.2	-1.5	0.0	-0.0
Delay disc. indifference point, 16s delay	0.4	0.4	1.3	0.7	0.7	0.8	0.8	0.6	-1.1	-0.6	0.1	-0.4	-0.8	-0.2	0.2
Delay disc. indifference point, 2s delay	0.2	0.2	0.9	0.4	0.4	0.4	0.4	0.4	-0.5	-0.9	-0.0	-0.3	-0.5	-0.2	0.2
Delay disc. indifference point, 24s delay	0.9	0.9	1.8	1.1	1.1	1.2	1.1	1.2	-1.3	0.8	0.0	-0.9	-0.7	-0.3	0.3
Delay disc. indifference point, 4s delay	0.3	0.3	1.3	0.4	0.3	0.3	0.2	0.1	-0.4	1.1	0.8	0.5	-0.5	0.8	-0.8
Delay disc. indifference point, 8s delay	0.6	0.6	2.1	0.7	0.7	0.7	0.6	0.2	-1.4	0.2	0.8	0.1	-1.2	0.6	-0.6
Indifference point function ln k	0.5	0.7	2.7	-0.9	-0.9	-0.7	-0.7	-0.5	0.8	1.6	-0.9	-0.1	0.3	-0.7	0.7
Indifference point function log k	0.5	0.7	2.7	-0.9	-0.9	-0.7	-0.7	-0.5	0.8	1.6	-0.9	-0.1	0.3	-0.7	0.7
Patch foraging total patch changes 0 sec	0.8	1.3	3.5	-0.9	-0.8	-0.8	-0.6	0.1	1.1	-0.3	-1.9	-1.0	1.0	-1.8	1.8
Patch foraging total patch changes 12 sec	0.1	0.1	0.2	-0.2	-0.1	-0.3	-0.2	0.1	0.5	-0.4	0.0	0.0	0.4	-0.0	0.0
Patch foraging total patch changes 18 sec	0.9	1.2	3.1	0.4	0.5	0.6	0.7	1.1	0.2	-0.5	-1.4	-1.8	0.1	-1.7	1.7
Patch foraging total patch changes 24 sec	2.0	2.5	6.2	0.3	0.4	0.5	0.8	1.2	0.1	-2.0	-2.1	-2.5	0.3	-2.5	2.5
Patch foraging total patch changes 6 sec	1.3	2.0	6.8	-1.3	-1.2	-1.2	-1.0	-0.4	1.5	-2.6	-1.6	-0.5	1.5	-1.4	1.4
Patch foraging time to switch 0 sec	2.6	4.0	7.2	2.7	2.6	2.5	2.4	1.9	-2.6	0.7	2.0	-0.4	-1.7	1.3	-1.3
Patch foraging water rate 0 sec	3.9	6.3	11.8	-3.3	-3.3	-3.2	-3.0	-2.4	3.4	-1.1	-2.2	0.8	2.6	-1.3	1.3
Patch foraging water rate 12 sec	0.7	1.1	1.9	-1.3	-1.3	-1.2	-1.1	-1.0	1.1	-0.1	-1.4	0.0	1.0	-1.1	1.1
Patch foraging water rate 18 sec	0.3	0.4	0.8	-0.9	-0.9	-0.9	-0.9	-0.9	0.6	-0.5	-0.0	0.8	0.2	0.2	-0.2
Patch foraging water rate 24 sec	0.3	0.5	1.1	-0.8	-0.9	-0.9	-0.9	-1.1	0.6	0.2	0.1	0.8	0.5	0.4	-0.4
Patch foraging water rate 6 sec	1.2	1.8	3.4	-1.8	-1.8	-1.8	-1.8	-1.7	1.5	0.9	-0.6	1.1	1.0	-0.0	0.0
Seeking ratio, delayed vs. immediate footshock	0.2	0.2	1.3	0.3	0.4	0.3	0.4	0.4	-0.3	-1.1	-0.2	-0.3	-0.1	-0.2	0.2
Distance traveled before self-admin	3.7	4.0	8.4	-2.7	-2.7	-2.6	-2.5	-2.2	2.9	0.8	-1.6	1.0	1.3	-0.8	0.8
Distance traveled after self-admin	1.7	1.9	3.9	-1.7	-1.8	-1.7	-1.7	-2.0	1.9	-0.8	-0.4	1.3	0.7	0.2	-0.2
Extensor digitorum longus weight	0.1	0.5	2.3	-0.2	-0.3	-0.3	-0.3	-1.1	-0.1	-1.5	0.6	0.7	-0.2	0.8	-0.8
Bone: elastic displacement	1.1	1.2	3.3	0.6	0.5	0.5	0.3	-0.3	-1.0	1.1	1.8	1.1	-0.9	1.8	-1.8
Bone: elastic work	0.4	0.5	1.4	0.3	0.2	0.1	0.0	-0.2	-0.4	0.7	1.1	0.9	-0.2	1.2	-1.2
Bone: endosteal estimation	0.6	1.4	9.3	-1.1	-1.1	-1.1	-0.9	-1.5	0.6	-3.1	-0.5	0.0	-0.3	-0.3	0.3
Bone: endosteal perimeter	1.5	3.1	7.2	-2.3	-2.3	-2.2	-2.1	-2.2	1.6	-2.7	-0.9	0.8	0.9	-0.3	0.3
Epididymis fat weight	0.5	1.1	1.9	-1.1	-1.2	-1.2	-1.3	-1.4	0.8	-1.4	0.3	1.2	0.6	0.7	-0.7
Delta time in closed arm before/after self-admin	0.3	0.3	0.8	0.6	0.6	0.6	0.6	0.6	-0.4	-0.9	0.2	-0.5	-0.5	-0.0	0.0
Delta time in open arm before/after self-admin	2.1	2.0	7.1	-1.4	-1.4	-1.4	-1.3	-1.1	2.2	2.7	-1.0	0.6	1.1	-0.5	0.5
Diff in mean of infusions in LGA sessions	1.4	1.5	11.0	0.9	1.0	0.8	0.9	1.0	-1.0	-3.3	0.8	-0.5	-0.6	0.3	-0.3
Delay discount exponential model param	0.3	0.3	1.2	-0.7	-0.6	-0.7	-0.6	-0.5	1.1	-0.2	-0.3	0.2	0.7	-0.2	0.2
Extinction: sum of active levers before priming	0.6	0.6	5.0	-0.2	-0.1	-0.3	-0.3	-0.1	0.8	2.2	0.6	0.5	0.4	0.6	-0.6
Active lever presses in extinction session 6	0.3	0.2	0.6	0.2	0.2	0.2	0.3	0.7	-0.1	0.3	-0.6	-0.7	-0.1	-0.8	0.8
Bone: final force	2.0	3.2	5.7	-2.4	-2.4	-2.4	-2.4	-2.3	2.1	0.7	-0.7	1.4	1.7	0.1	-0.1
Bone: final moment	1.5	2.4	4.4	-2.1	-2.1	-2.1	-2.1	-2.1	1.7	0.4	-0.5	1.3	1.3	0.1	-0.1
Food consumed during 24 hour testing period	0.5	0.6	1.5	0.6	0.6	0.7	0.8	0.8	-0.4	-1.0	-0.6	-1.2	-0.5	-0.9	0.9
Glucose	0.4	0.5	4.1	-0.6	-0.6	-0.6	-0.6	-0.7	0.4	-2.0	-0.3	0.1	0.2	-0.2	0.2
Heart weight	3.8	5.3	9.9	-3.1	-3.1	-3.0	-2.9	-2.6	2.9	-0.7	-2.0	0.9	2.2	-1.0	1.0
Delay discount hyperbolic model param	0.3	0.3	1.0	-0.6	-0.6	-0.7	-0.6	-0.5	1.0	-0.3	-0.3	0.2	0.7	-0.2	0.2
Intermittent access intake day 1-15 change	1.7	1.7	3.9	-1.5	-1.6	-1.4	-1.5	-2.0	1.5	2.0	-0.4	0.9	0.8	0.1	-0.1
Intermittent access intake escalation	1.4	1.3	4.1	-1.3	-1.3	-1.2	-1.2	-1.8	1.2	2.0	-0.4	0.8	0.6	0.2	-0.2
Intermittent access intake escalation 2	0.9	0.9	7.5	-0.6	-0.7	-0.5	-0.6	-0.9	0.9	2.7	-0.2	0.4	0.3	0.1	-0.1
Intermitt. access day 1 inactive lever presses	1.0	1.1	2.1	-1.3	-1.3	-1.1	-1.1	-0.9	0.9	0.1	-1.4	0.0	1.2	-0.9	0.9
Intermitt. access day 15 inactive lever presses	2.0	2.2	6.1	-1.1	-1.1	-0.8	-0.6	-0.2	1.0	-1.7	-2.5	-1.2	0.9	-2.3	2.3
Intermitt. access escalation Index	1.1	1.0	3.1	1.0	1.0	0.9	0.8	0.5	-1.3	-1.8	1.2	0.3	-0.5	1.0	-1.0
Intermittent access day 1 total infusions	0.4	0.5	2.5	0.7	0.7	0.7	0.7	0.6	-1.1	-1.6	0.2	-0.4	-0.4	0.0	-0.0
Intermittent access day 15 total infusions	0.4	0.4	1.3	-0.8	-0.9	-0.7	-0.7	-1.1	0.5	0.6	-0.4	0.4	0.5	-0.1	0.1
Intermittent access terminal intake (last 3 days)	0.5	0.6	1.0	-0.9	-0.9	-0.7	-0.7	-0.8	0.9	0.6	-1.0	-0.1	0.7	-0.7	0.7
Intermittent access total infusions	0.2	0.2	0.8	-0.4	-0.4	-0.3	-0.2	-0.3	0.3	-0.4	-0.9	-0.4	0.2	-0.8	0.8
Intermittent access day 1 locomotion	0.1	0.1	0.6	-0.2	-0.3	-0.1	-0.1	-0.4	-0.1	-0.8	-0.4	-0.0	0.0	-0.3	0.3
Intermittent access day 15 total locomotion	1.3	1.4	3.1	-1.3	-1.3	-1.1	-1.0	-0.7	1.3	0.6	-1.8	-0.3	1.1	-1.4	1.4
Intermittent access total locomotion	0.5	0.6	1.0	-0.8	-0.9	-0.6	-0.6	-0.9	0.7	0.9	-1.0	-0.1	0.4	-0.7	0.7
Intermittent access standard deviation	0.2	0.2	0.8	-0.5	-0.5	-0.4	-0.5	-0.8	0.5	0.9	-0.1	0.3	0.3	0.1	-0.1
Left kidney weight	1.0	2.8	4.5	-2.1	-2.1	-2.0	-1.8	-1.3	1.8	-1.5	-2.1	-0.2	1.3	-1.6	1.6
Right kidney weight	1.0	2.7	4.5	-2.0	-2.0	-1.9	-1.7	-1.1	2.1	-1.4	-1.9	-0.2	1.6	-1.4	1.4
Cocaine induced anxiety	5.2	6.0	13.0	2.0	2.1	2.2	2.5	3.0	-1.5	-3.6	-1.8	-3.4	-0.9	-2.6	2.6
Post-drug Anxiety	2.4	2.7	12.0	1.2	1.3	1.3	1.5	1.8	-1.2	-3.5	-0.9	-1.9	-0.5	-1.4	1.4
Baseline Anxiety	1.3	1.4	6.0	-0.8	-0.9	-0.9	-1.0	-1.4	0.5	2.4	0.8	1.5	0.3	1.1	-1.1
Tail length	2.3	6.9	17.9	-3.1	-3.2	-3.3	-3.4	-4.2	2.0	-0.2	0.9	3.0	1.0	1.9	-1.9
Length with tail	2.3	8.5	15.6	-3.9	-3.9	-4.0	-3.8	-3.7	3.1	-2.6	-1.2	2.1	2.3	-0.0	0.0
Length without tail	1.0	2.2	6.7	-1.8	-1.7	-1.7	-1.6	-1.1	1.5	-2.6	-1.2	0.7	1.4	-0.7	0.7
Times rat made contact with spout	0.1	0.1	1.2	0.1	0.2	0.2	0.2	0.2	-0.1	-1.1	-0.0	-0.3	-0.4	-0.2	0.2
Lifetime Intake	0.2	0.2	0.3	-0.5	-0.5	-0.4	-0.4	-0.5	0.4	-0.3	-0.6	-0.1	0.2	-0.4	0.4
Liver weight, left	0.8	1.3	3.3	-0.7	-0.6	-0.4	-0.2	-0.1	0.8	-1.3	-1.8	-1.3	0.2	-1.8	1.8
Liver weight, right	0.0	0.1	0.4	0.2	0.2	0.2	0.2	0.2	-0.2	-0.6	-0.0	-0.3	0.0	-0.2	0.2
Locomotor activity	0.7	1.2	6.9	-0.9	-0.9	-0.9	-1.0	-1.0	1.0	2.6	0.1	1.0	0.6	0.4	-0.4
Locomotor testing distance	0.1	0.2	0.5	-0.3	-0.3	-0.2	-0.2	-0.0	0.5	0.7	-0.6	-0.2	0.4	-0.5	0.5
Locomotor testing rearing	1.0	1.6	2.5	-1.4	-1.4	-1.3	-1.2	-0.6	1.5	1.2	-1.6	-0.1	1.4	-1.2	1.2
Locomotion in novel chamber	0.2	0.3	1.5	-0.3	-0.4	-0.2	-0.4	-0.8	0.0	1.2	0.3	0.3	-0.6	0.5	-0.5
Locomotion in novel chamber post-restriction	0.8	1.0	1.7	-1.0	-1.0	-1.1	-1.2	-1.2	0.9	0.3	0.7	1.3	0.6	1.1	-1.1
Fecal boli incidents, locomotor time 1	0.2	0.2	0.5	0.3	0.2	0.1	0.1	-0.0	-0.0	0.1	0.7	0.5	-0.2	0.7	-0.7
Change in fecal boli incidents, locomotor task	0.4	0.4	4.2	0.1	0.1	0.1	0.1	0.2	0.2	2.0	-0.0	-0.2	0.2	-0.0	0.0
Time >=10cm from walls, locomotor time 1	0.5	0.5	1.4	-0.1	-0.2	-0.2	-0.3	-0.8	-0.2	0.5	1.0	1.0	-0.4	1.2	-1.2
Bouts of movement, locomotor time 1	2.3	2.5	5.7	2.1	2.1	2.0	2.0	2.4	-2.0	0.8	0.9	-1.0	-0.6	0.4	-0.4
Total resting periods, locomotor time 1	2.1	2.3	5.0	2.0	2.0	1.9	1.8	2.2	-1.9	0.8	1.1	-0.8	-0.5	0.7	-0.7
Rest time, locomotor task time 1	0.4	0.5	0.9	0.8	0.8	0.7	0.7	0.9	-0.9	-1.0	0.7	-0.3	-0.0	0.6	-0.6
Distance moved, locomotor task time 1	0.1	0.1	0.4	-0.1	-0.1	-0.1	-0.1	-0.1	0.3	0.6	-0.2	0.1	0.1	-0.2	0.2
Vertical activity count, locomotor time 1	0.2	0.2	0.5	-0.4	-0.4	-0.3	-0.3	-0.4	0.6	0.7	-0.4	0.1	0.0	-0.4	0.4
Time >=10cm from walls, locomotor time 2	0.1	0.1	0.5	-0.0	-0.1	0.0	-0.0	-0.6	-0.4	-0.3	0.3	0.2	-0.7	0.3	-0.3
Bouts of movement, locomotor time 2	1.2	1.3	2.4	1.3	1.2	1.2	1.0	0.5	-1.5	0.4	1.6	0.4	-1.3	1.3	-1.3
Total resting periods, locomotor time 2	1.5	1.6	3.3	1.3	1.2	1.2	0.9	0.4	-1.5	0.7	1.8	0.6	-1.2	1.6	-1.6
Rest time, locomotor task time 2	0.6	0.7	1.6	0.7	0.7	0.6	0.4	0.5	-0.7	0.7	1.2	0.7	0.3	1.3	-1.3
Distance moved, locomotor task time 2	0.6	0.7	2.3	-0.1	-0.0	-0.0	0.2	0.5	0.3	-0.7	-1.3	-1.2	0.2	-1.5	1.5
Vertical activity count, locomotor time 2	0.8	0.9	2.2	-0.5	-0.5	-0.4	-0.2	0.0	0.8	-1.5	-1.4	-0.8	0.3	-1.5	1.5
Light reinforcement 1	0.4	0.7	1.5	-1.1	-1.1	-1.2	-1.2	-1.2	0.7	0.5	-0.1	0.8	0.1	0.2	-0.2
Light reinforcement 2	0.3	0.4	1.4	-0.7	-0.7	-0.7	-0.7	-0.7	0.2	-1.2	-0.1	0.4	0.3	0.1	-0.1
Bone: marrow area	0.7	1.5	9.6	-1.1	-1.1	-1.1	-0.9	-1.4	0.6	-3.1	-0.6	-0.0	-0.3	-0.4	0.4
Bone: maximum diameter	2.5	4.6	8.8	-3.0	-2.9	-3.0	-2.9	-2.6	2.4	-1.4	-1.0	1.5	1.7	-0.2	0.2
Bone: maximum force	0.4	0.7	1.2	-1.1	-1.1	-1.1	-1.0	-0.8	1.0	-0.0	-0.8	0.2	0.9	-0.4	0.4
Bone: maximum moment	0.2	0.3	0.6	-0.7	-0.7	-0.7	-0.6	-0.5	0.6	-0.3	-0.6	-0.1	0.5	-0.4	0.4
Mean time between licks in bursts	0.3	0.4	1.3	0.6	0.6	0.6	0.5	0.2	-1.0	-1.1	0.8	0.2	-0.6	0.7	-0.7
Mean num. licks in bursts	0.6	0.7	1.6	-0.4	-0.3	-0.4	-0.3	1.1	1.0	-0.3	-1.2	-0.5	1.3	-1.1	1.1
Cd content in liver	0.4	0.4	2.6	-0.6	-0.6	-0.5	-0.6	-0.5	0.7	1.6	-0.3	0.5	0.5	-0.1	0.1
Co content in liver	0.8	0.9	1.6	-1.2	-1.2	-1.2	-1.3	-1.1	1.1	0.8	-0.3	1.0	0.4	0.0	-0.0
Cu content in liver	1.0	1.2	2.3	-1.3	-1.3	-1.4	-1.5	-1.4	0.9	0.4	0.2	1.5	0.6	0.7	-0.7
Fe content in liver	0.2	0.2	0.7	-0.5	-0.5	-0.4	-0.3	-0.5	0.3	-0.8	-0.6	-0.1	-0.6	-0.5	0.5
K content in liver	0.2	0.2	0.9	-0.5	-0.5	-0.5	-0.5	-0.2	0.4	0.1	0.0	0.7	0.9	0.2	-0.2
Mg content in liver	1.0	1.0	1.8	-1.3	-1.3	-1.3	-1.4	-1.0	1.1	-0.2	-0.2	1.2	1.3	0.3	-0.3
Mn content in liver	1.1	1.2	2.2	-1.3	-1.4	-1.4	-1.5	-1.3	0.9	-0.1	0.1	1.4	1.2	0.6	-0.6
Na content in liver	0.2	0.2	0.4	0.1	0.2	0.2	0.3	0.5	-0.2	-0.2	-0.5	-0.7	0.0	-0.7	0.7
Rb content in liver	2.7	3.4	6.5	-2.3	-2.3	-2.3	-2.3	-1.8	2.3	-2.5	-0.6	1.5	1.4	0.1	-0.1
Se content in liver	1.4	1.7	3.3	-1.8	-1.8	-1.8	-1.7	-1.4	1.5	-0.6	-1.2	0.5	1.1	-0.7	0.7
Sr content in liver	0.4	0.4	1.6	-0.7	-0.7	-0.6	-0.7	-1.3	0.1	0.4	0.2	0.6	-0.6	0.4	-0.4
Zn content in liver	0.7	0.7	2.1	-0.8	-0.7	-0.7	-0.6	0.1	1.0	0.6	-1.2	-0.1	1.5	-1.0	1.0
Bone: minimum diameter	0.7	1.3	2.2	-1.5	-1.5	-1.5	-1.5	-1.4	1.0	-1.3	-0.2	0.9	0.9	0.2	-0.2
Time in familiar zone, hab. session 1	0.9	0.8	2.0	1.0	1.0	1.0	1.0	0.7	-1.2	-1.4	0.7	-0.4	-1.1	0.3	-0.3
Time in novel zone, hab. session 1	1.0	1.0	2.1	-1.0	-1.0	-1.0	-0.9	-0.4	1.4	0.7	-1.3	-0.3	1.0	-1.0	1.0
Total zone transitions, hab. session 1	0.7	1.0	1.7	-1.3	-1.3	-1.2	-1.1	-0.7	1.2	0.2	-1.2	0.1	0.6	-1.0	1.0
Total locomotion distance, hab. session 1	1.4	2.0	4.7	-1.6	-1.5	-1.4	-1.2	-0.5	1.8	-0.0	-2.2	-0.6	0.9	-1.9	1.9
Locomotion velocity, hab. session 1	1.5	2.1	4.6	-1.6	-1.5	-1.4	-1.2	-0.5	1.8	0.4	-2.1	-0.6	1.2	-1.8	1.8
Time in familiar zone, hab. session 2	0.5	0.6	1.3	0.9	0.9	1.0	1.0	1.1	-0.8	-0.4	-0.1	-0.9	-0.3	-0.4	0.4
Time in novel zone, hab. session 2	0.6	0.6	1.2	-0.9	-0.9	-0.9	-1.0	-1.1	0.8	0.4	0.2	0.9	0.3	0.4	-0.4
Total zone transitions, hab. session 2	1.7	2.1	3.9	-1.9	-1.9	-1.9	-2.0	-1.9	1.5	0.7	-0.3	1.5	1.2	0.4	-0.4
Total locomotion distance, hab. session 2	2.7	3.6	6.8	-2.2	-2.1	-2.0	-1.8	-0.7	2.6	0.2	-2.6	-0.4	2.1	-2.0	2.0
Locomotion velocity, hab. session 2	2.6	3.5	7.8	-1.9	-1.8	-1.7	-1.5	-0.3	2.4	0.1	-2.8	-0.7	2.2	-2.3	2.3
Novel to familiar place preference ratio	0.4	0.4	1.4	0.1	0.1	0.2	0.3	0.4	0.2	-1.2	-0.8	-0.9	-0.3	-0.9	0.9
Novelty place preference	0.5	0.5	1.8	0.3	0.4	0.4	0.5	0.6	-0.1	-1.4	-0.6	-0.9	-0.5	-0.8	0.8
Time in novel zone, NPP test	0.4	0.4	1.8	0.2	0.2	0.3	0.4	0.4	0.0	-1.3	-0.6	-0.8	-0.4	-0.8	0.8
Total zone transitions, NPP test	0.4	0.5	1.6	-0.9	-0.9	-0.8	-0.9	-0.9	0.6	1.2	-0.2	0.5	0.5	0.1	-0.1
Total locomotion distance, NPP test	2.4	3.2	6.9	-2.0	-1.9	-1.8	-1.5	-0.9	2.3	0.4	-2.6	-0.7	1.7	-2.1	2.1
Locomotion velocity, NPP test	1.8	2.5	6.1	-1.6	-1.6	-1.4	-1.2	-0.6	1.9	0.5	-2.5	-0.9	1.4	-2.1	2.1
Intraocular pressure	0.3	0.4	1.0	0.1	0.0	0.0	-0.1	-0.6	-0.4	-0.5	1.0	0.7	-1.0	1.0	-1.0
Delta distance traveled before/after self-admin	0.5	0.6	2.4	0.5	0.5	0.3	0.3	-0.0	-0.3	-1.6	1.1	0.4	-0.3	1.0	-1.0
Delta ambulatory time before/after self-admin	1.9	2.1	3.8	1.9	2.0	1.7	1.7	1.4	-1.6	-1.5	1.5	-0.4	-1.1	0.9	-0.9
Parametrial fat weight	0.2	0.3	0.7	0.8	0.8	0.8	0.8	0.5	-0.5	0.1	0.5	-0.4	-0.0	0.3	-0.3
Pavlov. Cond. lever latency	0.5	0.7	2.0	0.1	0.0	-0.0	-0.2	-0.6	-0.5	0.1	1.4	0.9	-1.0	1.3	-1.3
Pavlov. Cond. magazine entry latency	0.6	0.8	2.3	-1.0	-0.9	-0.9	-0.8	-0.4	1.1	-0.3	-1.2	-0.0	1.5	-0.9	0.9
Pavlov. Cond. change in total contacts	0.4	0.4	1.5	-0.5	-0.5	-0.5	-0.3	-0.3	0.5	-1.2	-0.9	-0.3	0.7	-0.8	0.8
Pavlov. Cond. index score	0.4	0.4	1.4	-0.4	-0.4	-0.3	-0.2	0.1	0.6	-0.5	-1.1	-0.4	1.2	-0.9	0.9
Pavlov. Cond. latency score	0.6	0.7	2.2	-0.4	-0.3	-0.3	-0.1	0.4	0.7	-0.2	-1.5	-0.7	1.3	-1.3	1.3
Pavlov. Cond. lever contacts	0.5	0.5	1.5	-0.5	-0.5	-0.4	-0.3	0.1	0.7	-0.5	-1.2	-0.4	1.2	-1.0	1.0
Pavlov. Cond. magazine entry number	0.3	0.4	0.7	0.6	0.6	0.7	0.7	0.8	-0.3	0.3	-0.2	-0.8	-0.9	-0.5	0.5
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.4	-0.5	-0.5	-0.5	-0.6	-0.7	0.4	0.4	0.3	0.5	-0.1	0.4	-0.4
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	1.0	-0.3	-0.3	-0.2	-0.2	0.1	0.4	-0.7	-0.9	-0.3	1.0	-0.7	0.7
Pavlov. Cond. response bias	0.4	0.5	1.1	-0.8	-0.8	-0.8	-0.7	-0.8	0.7	-0.7	-0.5	0.4	1.0	-0.2	0.2
Pavlov. Cond. lever latency	1.8	2.4	5.0	2.1	2.1	2.1	2.1	2.2	-1.4	-0.5	0.2	-1.6	-1.1	-0.4	0.4
Pavlov. Cond. magazine entry latency	0.2	0.2	0.9	-0.3	-0.3	-0.3	-0.2	-0.2	0.1	-0.9	-0.5	-0.2	0.5	-0.4	0.4
Pavlov. Cond. change in total contacts	1.2	1.7	3.3	-1.6	-1.7	-1.7	-1.8	-1.8	0.9	-0.3	0.2	1.6	1.0	0.7	-0.7
Pavlov. Cond. index score	1.3	1.6	3.6	-1.6	-1.7	-1.7	-1.7	-1.9	0.9	-0.2	0.0	1.5	1.0	0.5	-0.5
Pavlov. Cond. latency score	0.9	1.2	2.3	-1.4	-1.5	-1.5	-1.5	-1.5	0.9	-0.3	-0.2	1.0	1.0	0.2	-0.2
Pavlov. Cond. lever contacts	1.8	2.4	4.9	-2.1	-2.1	-2.1	-2.1	-2.2	1.4	0.5	-0.3	1.6	1.0	0.3	-0.3
Pavlov. Cond. magazine entry number	0.3	0.4	1.0	0.7	0.7	0.7	0.7	1.0	-0.2	0.4	-0.1	-0.7	-0.6	-0.3	0.3
Pavlov. Cond. intertrial magazine entries	0.3	0.4	1.0	0.4	0.4	0.5	0.6	0.3	-0.3	0.9	-0.4	-1.0	-1.0	-0.6	0.6
Pavlov. Cond. lever-magazine prob. diff.	1.0	1.3	2.7	-1.5	-1.5	-1.5	-1.6	-1.6	0.8	-0.3	0.0	1.3	1.0	0.5	-0.5
Pavlov. Cond. response bias	1.9	2.5	5.3	-2.1	-2.2	-2.2	-2.2	-2.3	1.4	0.0	-0.3	1.6	1.2	0.4	-0.4
Time in closed arm before self-admin	0.3	0.4	0.8	0.9	0.9	0.8	0.8	0.7	-0.2	-0.0	0.4	-0.4	-0.7	0.1	-0.1
Time in closed arm after self-admin	1.3	1.3	2.4	1.6	1.6	1.4	1.4	1.1	-1.0	0.2	1.3	-0.2	-1.2	0.9	-0.9
Time in open arm before self-admin	0.4	0.4	1.4	0.5	0.5	0.5	0.5	0.2	-1.2	-1.0	0.6	-0.3	-0.7	0.4	-0.4
Time in open arm after self-admin	1.0	1.1	2.2	-1.1	-1.1	-1.0	-0.9	-0.7	1.3	0.6	-1.5	-0.5	0.8	-1.3	1.3
Bone: periosteal estimation	1.2	2.5	4.9	-2.1	-2.1	-2.1	-2.1	-2.2	1.5	-1.9	-0.5	1.1	0.8	0.1	-0.1
Bone: periosteal perimeter	1.9	3.2	5.6	-2.3	-2.3	-2.3	-2.2	-2.0	1.9	-2.4	-0.9	1.0	1.4	-0.2	0.2
Bone: post-yield work	0.7	1.0	1.8	1.0	1.1	1.1	1.2	1.2	-1.1	-0.8	-0.3	-1.3	-1.0	-0.7	0.7
Progressive ratio test 1 active lever presses	1.5	1.5	2.8	-1.6	-1.6	-1.6	-1.7	-1.7	1.4	0.6	-0.2	1.2	0.9	0.4	-0.4
Progressive ratio test 1 breakpoint	1.8	1.8	3.5	-1.7	-1.8	-1.8	-1.8	-1.9	1.6	0.5	-0.1	1.4	1.0	0.5	-0.5
Progressive ratio test 1 inactive lever presses	1.3	1.4	2.2	-1.5	-1.5	-1.4	-1.3	-0.8	1.2	-0.7	-1.5	0.0	1.4	-1.0	1.0
Progressive ratio test 2 active lever presses	0.5	0.5	1.0	-0.9	-0.8	-0.8	-0.7	-0.5	0.9	0.2	-1.0	-0.2	0.8	-0.8	0.8
Progressive ratio test 2 breakpoint	0.2	0.3	0.5	-0.6	-0.6	-0.6	-0.5	-0.5	0.6	-0.2	-0.7	-0.1	0.6	-0.5	0.5
Progressive ratio test 2 inactive lever presses	1.8	2.0	3.9	-1.7	-1.6	-1.5	-1.3	-1.0	1.4	-1.4	-2.0	-0.2	1.3	-1.5	1.5
Incentive Sensitization - Responses	0.4	0.4	4.0	-0.1	-0.1	-0.1	-0.1	-0.1	-0.3	-2.0	0.0	-0.0	0.4	0.1	-0.1
Incentive Sensitization - Breakpoint	0.4	0.4	4.1	-0.0	0.0	-0.0	0.0	0.1	-0.3	-2.0	-0.2	-0.3	0.4	-0.2	0.2
Sum of active levers in priming session hrs 5-6	0.7	0.7	1.4	-1.0	-0.9	-1.0	-0.8	-0.3	1.2	-1.1	-0.9	-0.1	0.8	-0.8	0.8
Progressive ratio	3.4	3.9	7.3	2.6	2.7	2.7	2.7	2.6	-2.0	0.7	0.5	-2.0	-1.7	-0.4	0.4
Food seeking constrained by brief footshock	1.6	2.0	4.5	-1.2	-1.1	-1.1	-0.9	-0.1	2.1	0.5	-2.1	-0.9	1.5	-1.9	1.9
Seeking ratio, punishment vs. effort	4.0	4.8	8.8	-3.0	-2.9	-2.9	-2.8	-2.3	2.8	-0.5	-1.6	1.3	2.4	-0.7	0.7
Retroperitoneal fat weight	0.0	0.1	0.6	0.0	0.0	0.1	0.2	-0.1	-0.3	-0.8	-0.4	-0.5	-0.2	-0.5	0.5
Reaction time number correct	0.3	0.4	0.8	-0.5	-0.5	-0.5	-0.3	-0.1	0.7	-0.9	-0.9	-0.4	0.1	-0.9	0.9
Reaction time mean minus median	0.6	0.8	1.5	1.0	1.0	1.0	1.1	1.2	-0.6	-1.2	-0.3	-1.2	-0.1	-0.6	0.6
Reaction time mean minus median AUC	0.3	0.4	0.8	0.5	0.6	0.6	0.6	0.8	-0.1	-0.9	-0.5	-0.9	0.3	-0.6	0.6
Reaction time num false alarms	1.9	2.6	4.8	-2.2	-2.2	-2.1	-2.0	-1.5	1.8	0.6	-1.5	0.6	1.6	-0.9	0.9
Reaction time num false alarms AUC	1.5	2.1	3.9	-2.0	-2.0	-1.9	-1.9	-1.5	1.5	1.0	-0.9	1.0	1.4	-0.4	0.4
Reaction time trials correct on left	0.3	0.4	0.8	-0.5	-0.5	-0.5	-0.3	-0.1	0.7	-0.9	-0.9	-0.4	0.1	-0.9	0.9
Reaction time trials on left	0.3	0.4	0.9	-0.6	-0.6	-0.5	-0.4	-0.2	0.8	-0.9	-0.9	-0.3	0.2	-0.9	0.9
Reaction time mean	0.0	0.0	0.1	-0.1	-0.2	-0.1	-0.2	-0.4	0.1	0.3	0.1	0.3	0.2	0.3	-0.3
Reaction time mean AUC	0.0	0.0	0.1	-0.1	-0.1	-0.1	-0.1	-0.3	0.1	0.1	0.1	0.2	0.3	0.2	-0.2
Median of all reaction times	0.2	0.2	0.6	-0.5	-0.5	-0.5	-0.5	-0.8	0.4	0.7	0.0	0.5	0.3	0.3	-0.3
Reaction time omissions	0.8	1.0	2.3	-1.3	-1.3	-1.3	-1.3	-0.6	1.5	0.4	-0.8	0.6	1.4	-0.4	0.4
Reaction time false alarm rate	1.0	1.4	2.4	-1.5	-1.5	-1.5	-1.6	-1.1	1.1	1.0	-0.6	0.9	1.4	-0.1	0.1
Reaction time premature initiation rate	0.2	0.3	0.6	-0.1	-0.1	-0.1	-0.2	-0.8	-0.4	0.1	0.8	0.5	-0.7	0.7	-0.7
Reaction time premature initiations	0.1	0.1	0.4	-0.2	-0.2	-0.2	-0.2	-0.6	-0.0	0.1	0.1	0.1	-0.6	0.1	-0.1
Std. dev. reaction times	0.1	0.1	0.4	-0.3	-0.3	-0.3	-0.4	-0.5	0.3	-0.0	0.2	0.5	0.6	0.3	-0.3
Reaction time trials completed	0.3	0.4	0.9	-0.6	-0.6	-0.5	-0.4	-0.2	0.8	-0.9	-0.9	-0.3	0.2	-0.9	0.9
Reaction time trials AUC	0.3	0.4	0.8	-0.6	-0.5	-0.5	-0.4	-0.2	0.8	-0.9	-0.9	-0.3	0.2	-0.9	0.9
Run reversals in cocaine runway, females	0.4	0.4	1.2	-0.9	-0.9	-0.8	-0.8	-1.1	0.3	-0.3	-0.7	0.1	0.1	-0.5	0.5
Run reversals in cocaine runway, males	1.7	1.7	3.5	-1.7	-1.7	-1.7	-1.7	-1.2	1.5	-0.6	-0.4	1.2	1.9	0.2	-0.2
Latency to leave start box in cocaine runway	0.7	0.8	1.8	1.1	1.1	1.0	1.1	1.3	-1.1	-1.0	0.4	-0.7	-0.6	-0.0	0.0
Latency to leave start box in cocaine runway, F	1.2	1.3	3.1	1.6	1.7	1.5	1.5	1.8	-1.1	0.3	0.9	-0.6	-0.5	0.4	-0.4
Latency to leave start box in cocaine runway, M	1.1	1.0	7.1	-0.5	-0.4	-0.4	-0.2	0.0	-0.2	-2.7	-1.1	-0.8	-0.1	-1.2	1.2
Std. dev. time between licks in bursts	0.5	0.6	2.9	-0.9	-0.9	-0.8	-0.8	-1.2	0.5	-1.7	-0.1	0.5	-0.1	0.2	-0.2
Total sessions with >9 infusions	0.2	0.2	1.1	0.1	0.1	0.1	0.1	-0.3	-0.3	-1.0	0.6	0.3	-0.4	0.6	-0.6
Short access day 1 total inactive lever presses	0.2	0.2	1.1	-0.2	-0.3	-0.1	-0.1	-0.4	-0.7	-1.0	-0.4	0.2	0.3	-0.2	0.2
Short access day 10 total inactive lever presses	2.0	2.2	6.5	0.2	0.2	0.5	0.7	1.2	0.4	-0.1	-2.4	-2.2	0.5	-2.6	2.6
Short access day 1 total infusions	0.0	0.0	0.4	0.1	0.1	0.1	0.1	0.0	-0.0	-0.6	-0.0	-0.0	-0.1	0.0	-0.0
Short access day 10 total infusions	0.1	0.2	0.7	0.3	0.3	0.3	0.3	0.1	-0.6	-0.9	0.2	-0.2	-0.5	0.1	-0.1
Short access total infusions	0.2	0.2	1.9	0.0	-0.0	-0.0	-0.0	-0.2	-0.0	-1.4	0.2	0.1	-0.2	0.2	-0.2
Short access day 1 locomotion	0.2	0.2	0.4	0.3	0.3	0.5	0.5	0.5	-0.1	-0.5	-0.5	-0.7	-0.2	-0.6	0.6
Short access day 10 total locomotion	0.5	0.6	1.3	-0.7	-0.8	-0.7	-0.8	-1.1	0.7	1.1	0.0	1.0	0.2	0.4	-0.4
Short access total locomotion	0.3	0.3	0.7	-0.6	-0.7	-0.6	-0.6	-0.7	0.8	-0.2	-0.5	0.2	0.3	-0.3	0.3
One hour access (0.3 mA shock)	0.6	0.7	1.3	-1.0	-1.1	-0.9	-0.9	-1.0	0.6	1.2	-0.8	0.2	0.7	-0.4	0.4
Compulsive drug intake	1.3	1.4	5.0	1.3	1.3	1.4	1.2	0.9	-2.2	0.8	0.8	-0.4	-1.3	0.5	-0.5
One hour access (shock baseline)	0.4	0.5	1.5	-0.8	-0.7	-0.8	-0.7	-0.5	1.2	0.5	-0.7	0.0	1.0	-0.4	0.4
Social response proportion	1.1	1.2	3.8	-1.1	-1.1	-1.1	-1.0	-0.3	1.2	-2.0	-1.0	0.0	1.6	-0.7	0.7
Social responses	2.0	2.6	4.5	-2.0	-2.0	-2.1	-2.1	-1.4	1.7	-1.4	-0.3	1.5	2.1	0.4	-0.4
Social time	0.2	0.3	0.9	-0.5	-0.5	-0.6	-0.7	-0.4	0.1	0.9	0.1	0.8	0.8	0.4	-0.4
Soleus weight	0.2	0.6	3.3	-0.8	-0.8	-0.7	-0.6	-0.9	0.2	-1.8	-0.6	-0.2	-0.1	-0.5	0.5
Bone: stiffness	1.0	1.6	2.9	-1.7	-1.7	-1.7	-1.6	-1.0	1.7	0.2	-1.1	0.4	1.5	-0.6	0.6
Tibialis anterior weight	0.7	2.3	5.7	-1.9	-2.0	-2.0	-2.0	-2.4	1.3	-0.1	-0.0	1.7	1.1	0.7	-0.7
Time to tail flick, vehicle, before self-admin	1.2	1.2	3.0	0.4	0.4	0.6	0.8	0.7	-0.4	-1.1	-1.5	-1.7	-0.7	-1.7	1.7
Time to tail flick, vehicle, after self-admin	0.1	0.2	0.7	0.3	0.2	0.3	0.2	-0.2	-0.1	0.8	0.5	0.0	-0.5	0.4	-0.4
Time to tail flick, test, before self-admin	0.6	0.6	1.2	-0.5	-0.5	-0.6	-0.7	-0.8	-0.3	-1.1	0.7	1.0	0.4	1.0	-1.0
Time to tail flick, test, after self-admin	1.2	1.2	2.6	0.8	0.8	1.0	1.1	1.3	-0.1	1.0	-1.1	-1.6	-0.3	-1.5	1.5
Delta time to tail flick, vehicle, before/after SA	1.3	1.3	2.0	-1.1	-1.1	-1.2	-1.3	-1.3	1.3	1.2	0.7	1.4	0.8	1.1	-1.1
Delta time to tail flick, test, before/after SA	1.5	1.3	3.4	0.5	0.6	0.7	0.9	1.1	0.0	-0.0	-1.5	-1.8	-0.4	-1.8	1.8
Tibia length	2.2	6.3	14.4	-2.1	-2.2	-2.4	-2.7	-3.5	0.8	-0.6	2.2	3.8	0.6	3.1	-3.1
Ambulatory time before self-admin	2.2	2.3	4.5	-2.0	-2.0	-1.9	-1.9	-2.1	2.1	1.1	-0.6	1.2	0.4	0.0	-0.0
Ambulatory time after self-admin	1.1	1.2	2.7	-1.1	-1.1	-1.2	-1.2	-1.5	1.6	-0.5	0.4	1.4	0.4	0.8	-0.8
Bone: tissue strength	0.4	0.4	0.9	-0.6	-0.6	-0.5	-0.5	-0.2	0.8	0.5	-0.9	-0.2	0.9	-0.7	0.7
Total heroin consumption	1.9	2.2	4.4	-2.0	-1.9	-2.1	-2.0	-1.1	2.1	0.5	-0.7	1.3	1.8	-0.1	0.1
Bone: trabecular number	1.4	2.2	4.7	-2.1	-2.1	-2.0	-1.9	-2.2	1.7	0.2	-0.9	0.9	0.9	-0.3	0.3
Bone: trabecular spacing	0.2	0.3	1.1	0.7	0.7	0.6	0.6	1.0	-0.2	0.6	0.1	-0.4	0.4	-0.1	0.1
Bone: trabecular thickness	0.5	0.6	1.2	-1.1	-1.1	-1.0	-1.0	-0.8	1.0	0.4	-0.5	0.5	0.7	-0.2	0.2
Bone: trabecular tissue density	1.2	1.7	3.3	-1.7	-1.6	-1.6	-1.6	-1.0	1.8	0.4	-1.2	0.5	1.6	-0.7	0.7
Water consumed over 24 hours	0.1	0.1	0.3	0.4	0.3	0.4	0.3	-0.1	-0.3	0.3	0.6	0.0	-0.5	0.4	-0.4
Number of responses in last shaping day	0.0	0.0	0.1	0.3	0.3	0.3	0.3	0.2	0.1	-0.2	0.1	-0.2	-0.3	0.0	-0.0