Hub : Genes

LOC102547851

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio XR_005490342.1 0.26 0.12 2.2e-11 0.21 0.14 0.27 0.16 1.4e-09 1.4e-06 4.0e-12 3.2e-07
2 BLA alternative polyA XR_005490342.1 0.23 0.12 2.1e-09 0.12 0.15 0.15 0.14 9.2e-07 3.2e-08 2.9e-08 6.1e-08
3 BLA isoform ratio XR_005490342.1 0.32 0.12 3.3e-16 0.22 0.27 0.25 0.27 3.1e-12 1.3e-14 1.6e-13 1.2e-14
4 pVTA isoform ratio XR_005490347.1 0.25 0.13 1.2e-09 0.23 0.12 0.21 0.18 2.9e-10 1.0e-05 1.6e-09 2.7e-08
5 pVTA alternative polyA XR_005490342.1 0.16 0.09 1.2e-06 0.17 0.07 0.15 0.02 4.9e-08 4.7e-04 3.4e-07 3.5e-02
6 pVTA alternative polyA XR_005490347.1 0.21 0.11 1.4e-09 0.24 0.1 0.19 0.06 1.0e-10 4.5e-05 8.0e-09 1.3e-03
7 Brain intron excision ratio chr10_56559337_56565515 0.06 0.04 2.1e-05 0.05 0.06 0.05 0.05 2.1e-05 4.7e-06 3.0e-05 1.2e-05
8 BLA alternative polyA XR_005490347.1 0.26 0.13 2.7e-11 0.19 0.17 0.18 0.18 2.5e-10 2.2e-09 9.0e-10 1.0e-09
9 BLA isoform ratio XR_005490347.1 0.24 0.12 1.4e-10 0.2 0.19 0.2 0.2 6.6e-11 2.1e-10 8.5e-11 8.8e-11
10 pVTA intron excision ratio chr10_56559337_56565515 0.11 0.07 5.4e-05 0.1 0.03 0.08 0.01 3.8e-05 1.4e-02 1.7e-04 1.4e-01
11 BLA intron excision ratio chr10_56559337_56565515 0.06 0.05 6.6e-03 0.03 0.01 -0 0.01 9.3e-03 1.5e-01 9.4e-01 9.5e-02
12 Brain alternative polyA XR_005490347.1 0.17 0.09 1.1e-16 0.18 0.18 0.17 0.18 8.2e-17 1.7e-16 4.6e-16 1.4e-16
13 PL alternative polyA XR_005490347.1 0.02 0.02 9.8e-03 0 0 0 0 1.8e-01 1.4e-01 2.5e-01 3.2e-01
14 NAcc alternative polyA XR_005490347.1 0.04 0.03 2.2e-04 0.02 0.03 0.02 0.02 1.2e-03 4.2e-04 3.9e-03 2.5e-03
15 Brain isoform ratio XR_005490347.1 0.04 0.03 8.4e-04 0.02 0.03 0.03 0.04 7.8e-03 6.1e-04 3.7e-04 2.0e-04
16 Brain alternative polyA XR_005490346.1 0.04 0.03 3.5e-04 0.03 0.03 0.03 0.03 5.6e-04 5.1e-04 9.7e-04 1.9e-03
17 Brain alternative polyA XR_005490345.1 0.06 0.05 1.3e-05 0.04 0.05 0.03 0.05 2.5e-04 1.3e-05 5.4e-04 2.8e-05
18 Brain intron excision ratio chr10_56574942_56576731 0.32 0.14 0.0e+00 0.24 0.25 0.25 0.25 6.5e-22 3.9e-23 4.5e-23 1.6e-23
19 NAcc alternative polyA XR_005490345.1 0.03 0.03 8.4e-03 0 0.01 -0 0.01 1.3e-01 1.8e-02 3.8e-01 5.6e-02
20 BLA intron excision ratio chr10_56574942_56576731 0.2 0.11 1.3e-06 0.07 0.07 0.03 0.07 1.9e-04 1.3e-04 1.3e-02 2.1e-04
21 Brain gene expression LOC102547851 0.11 0.08 5.4e-07 0.07 0.06 0.05 0.07 4.3e-07 2.7e-06 9.8e-06 6.0e-07
22 pVTA intron excision ratio chr10_56574942_56576731 0.39 0.14 5.6e-17 0.36 0.39 0.38 0.4 2.6e-16 4.6e-18 9.6e-18 1.0e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.71.12.90.50.5-0.2-0.91.0-1.0-0.6-0.7-0.70.70.5-0.41.21.11.1-1.2-1.41.7-1.51.5-1.71.5
Area under the delay curve0.40.42.3-1.0-0.70.11.5-1.21.20.30.10.1-0.1-0.60.4-0.4-0.4-0.30.40.4-0.50.6-0.40.6-0.4
BMI with tail0.30.91.41.11.0-1.0-0.71.0-1.0-1.0-0.9-0.90.91.2-1.11.01.01.1-1.0-0.90.8-0.80.8-0.60.4
BMI without tail0.71.42.71.61.1-0.9-1.01.4-1.4-1.1-1.0-1.01.31.6-1.31.21.21.2-1.2-1.11.0-1.11.0-0.90.7
Body weight1.04.28.70.60.9-0.6-1.31.3-1.3-1.5-1.5-1.51.71.4-1.42.42.32.8-2.5-2.72.9-2.92.9-2.92.6
Weight adjusted by age1.71.94.61.52.0-2.1-1.11.1-1.1-1.7-1.9-1.91.81.5-1.61.51.30.8-1.3-1.20.9-0.80.7-0.50.4
Bone surface1.01.82.41.01.1-1.3-1.41.3-1.3-1.4-1.5-1.51.51.2-1.21.51.51.3-1.5-1.41.3-1.31.3-1.10.9
Bone volume1.42.43.21.41.5-1.6-1.61.5-1.5-1.7-1.8-1.81.71.4-1.51.71.71.5-1.7-1.61.4-1.41.3-1.10.9
Breakpoint value in progressive ratio session0.70.81.50.70.8-0.5-0.90.8-0.8-0.6-0.6-0.60.70.9-0.91.00.90.8-1.0-1.11.0-1.21.1-1.21.0
Number of licking bursts0.30.41.9-0.3-0.40.40.4-0.50.50.60.60.6-0.6-0.40.8-0.7-0.7-1.40.70.6-0.60.6-0.60.4-0.5
Context. condit. distance diff. score1.31.51.91.01.1-1.1-1.01.2-1.2-1.2-1.4-1.41.31.3-1.31.41.31.2-1.3-1.41.4-1.21.2-1.11.1
Locomotion velocity, session 13.84.26.31.31.3-0.9-2.52.4-2.4-1.7-1.6-1.61.72.0-2.12.12.22.5-2.2-2.22.3-2.32.3-2.02.0
Locomotion distance, session 11.21.54.11.41.3-1.1-2.01.9-1.9-1.3-1.1-1.11.21.6-1.31.11.21.1-1.1-0.90.9-0.80.7-0.50.6
Locomotion velocity, session 20.30.40.9-0.1-0.20.6-0.90.7-0.7-0.00.30.3-0.10.5-0.40.30.50.9-0.6-0.60.9-0.90.9-0.90.8
Locomotion distance, session 20.91.34.61.00.8-0.2-2.11.8-1.8-0.8-0.5-0.50.61.2-0.90.91.01.1-1.0-0.91.2-1.21.1-1.01.0
Locomotion velocity, session 32.52.95.5-2.3-2.21.92.0-2.12.11.71.71.7-1.7-2.01.7-1.7-1.6-1.11.61.5-1.51.3-1.11.0-0.8
Locomotion distance, session 30.10.10.2-0.4-0.40.40.0-0.20.20.30.40.4-0.4-0.40.2-0.3-0.3-0.20.30.3-0.20.1-0.10.10.0
Stereotopy head waving bouts, day 30.10.10.20.1-0.00.3-0.40.5-0.5-0.10.00.0-0.00.2-0.00.10.20.4-0.2-0.20.3-0.30.3-0.20.2
Stereotopy head waving duration, day 30.30.41.50.60.3-0.2-0.30.4-0.4-0.10.00.00.10.3-0.2-0.5-0.3-0.30.40.8-1.00.9-0.91.2-1.2
Locomotion velocity, session 70.00.00.20.10.3-0.5-0.10.0-0.0-0.2-0.2-0.20.20.0-0.40.10.1-0.2-0.0-0.0-0.10.1-0.10.1-0.2
Locomotion distance, session 70.00.00.50.20.3-0.2-0.1-0.10.10.20.00.0-0.1-0.1-0.0-0.1-0.2-0.70.20.10.00.1-0.2-0.1-0.1
Stereotopy head waving bouts, day 71.82.04.21.71.6-1.1-1.92.1-2.1-1.4-1.3-1.31.31.7-1.41.31.41.5-1.4-1.21.1-1.11.1-0.70.8
Stereotopy head waving duration, day 72.12.54.71.71.7-1.2-2.12.2-2.2-1.6-1.4-1.41.41.8-1.61.51.71.9-1.6-1.41.3-1.41.3-0.91.0
Locomotion velocity, session 81.61.93.61.31.2-1.0-1.81.8-1.8-1.5-1.3-1.31.31.8-1.81.31.51.9-1.4-1.11.0-1.11.1-0.60.7
Locomotion distance, session 82.84.16.31.61.6-1.2-2.52.4-2.4-1.8-1.7-1.71.72.3-2.02.12.12.3-2.2-2.12.3-2.22.1-1.92.0
Degree of sensitization distance0.40.41.20.91.1-1.1-0.50.5-0.5-0.7-0.9-0.90.90.8-0.70.70.5-0.1-0.5-0.60.6-0.30.3-0.50.2
Degree of sensitization stereotypy2.12.33.31.41.4-1.0-1.81.8-1.8-1.4-1.3-1.31.31.6-1.41.61.61.8-1.6-1.61.6-1.61.5-1.41.4
Conditioned locomotion1.31.52.2-1.2-1.00.71.5-1.41.41.11.11.1-1.1-1.31.1-1.3-1.3-1.51.31.3-1.31.3-1.21.1-1.1
Cocaine response after cond. corrected0.50.62.4-1.5-1.10.91.0-1.11.10.70.60.6-0.5-1.10.6-0.2-0.3-0.20.2-0.20.4-0.40.4-0.80.8
Cocaine response after cond. not corrected0.30.31.3-1.1-0.60.50.7-0.80.80.40.30.3-0.2-0.70.30.1-0.00.0-0.1-0.40.6-0.50.6-0.90.8
Cocaine response before conditioning0.70.91.71.21.2-1.1-1.01.1-1.1-1.1-1.0-1.01.11.3-1.00.90.90.9-0.9-0.70.6-0.60.6-0.30.3
Saline control response0.40.51.41.20.9-0.9-0.91.0-1.0-0.7-0.8-0.80.80.7-0.50.70.60.2-0.5-0.50.6-0.40.3-0.40.3
Bone: connectivity density1.21.93.71.00.9-0.7-1.41.4-1.4-1.0-1.2-1.21.21.1-0.91.51.41.4-1.5-1.71.9-1.71.7-1.71.6
Bone: cortical apparent density1.21.63.0-0.9-0.91.21.2-1.21.21.41.41.4-1.4-1.31.6-1.5-1.5-1.71.51.3-1.11.2-1.20.9-0.8
Bone: cortical area0.60.92.1-0.9-0.70.21.4-1.41.40.60.40.4-0.4-0.70.7-0.8-0.9-1.10.90.9-1.21.1-1.01.0-1.0
Bone: cortical porosity0.80.93.2-1.8-1.61.41.2-1.11.10.91.01.0-1.0-0.80.7-0.2-0.20.60.0-0.30.5-0.60.7-0.90.9
Bone: cortical porosity0.91.03.7-1.9-1.71.41.4-1.31.31.01.11.1-1.1-0.80.7-0.4-0.30.40.2-0.10.3-0.40.5-0.60.7
Bone: cortical thickness2.33.86.3-2.2-2.21.92.5-2.42.42.12.12.1-2.1-1.82.0-2.0-2.0-1.91.91.7-1.61.5-1.41.0-1.1
Bone: cortical thickness2.73.26.9-2.6-2.52.42.2-2.12.12.22.22.2-2.1-2.02.1-1.5-1.6-1.41.40.9-0.50.5-0.4-0.20.2
Bone: cortical tissue density1.01.32.5-0.7-0.81.11.0-1.11.11.31.31.3-1.2-1.21.4-1.3-1.3-1.61.31.2-0.91.0-1.10.7-0.7
Condit. Reinf. active minus inactive responses1.01.12.8-1.7-1.41.11.5-1.51.51.30.90.9-0.9-1.61.2-0.6-0.8-1.10.70.20.20.1-0.0-0.60.5
Condit. Reinf. active-inactive response ratio1.11.13.5-1.9-1.40.91.7-1.81.81.10.80.8-0.7-1.71.0-0.6-0.8-1.00.70.2-0.00.2-0.1-0.40.4
Condit. Reinf. active responses0.40.51.3-1.0-0.90.90.7-0.80.81.00.80.8-0.7-1.20.9-0.5-0.6-1.00.50.10.3-0.10.1-0.60.5
Condit. Reinf. inactive responses0.10.10.30.60.20.1-0.60.5-0.50.10.20.2-0.20.10.2-0.2-0.2-0.40.20.20.00.1-0.20.1-0.1
Incentive salience index mean0.81.02.7-1.7-1.41.31.2-1.21.21.31.01.0-0.9-1.51.0-0.5-0.6-0.70.5-0.10.6-0.30.4-1.00.9
Condit. Reinf. lever presses0.70.93.1-1.1-1.01.30.0-0.10.10.80.80.8-0.8-0.50.40.10.10.3-0.3-0.81.5-1.31.2-1.71.7
Condit. Reinf. active minus inactive responses0.20.30.9-0.9-0.80.80.4-0.40.40.70.60.6-0.6-0.80.7-0.2-0.3-0.30.2-0.10.5-0.30.3-0.60.6
Condit. Reinf. active-inactive response ratio0.90.92.5-1.6-1.31.01.4-1.31.31.10.90.9-0.8-1.41.1-0.6-0.8-0.90.70.30.10.1-0.1-0.40.4
Condit. Reinf. active responses0.10.10.4-0.6-0.40.6-0.10.1-0.10.40.30.3-0.3-0.50.6-0.1-0.1-0.10.1-0.10.4-0.30.3-0.50.5
Condit. Reinf. inactive responses0.20.21.00.90.7-0.4-1.00.9-0.9-0.4-0.4-0.40.30.5-0.10.10.20.1-0.10.1-0.10.1-0.20.4-0.4
Condit. Reinf. lever presses0.50.71.4-0.1-0.30.30.4-0.40.40.70.70.7-0.6-0.70.9-1.0-1.0-1.21.01.1-1.01.1-1.11.0-1.0
Condit. Reinf. lever reinforcers received0.10.10.4-0.5-0.40.6-0.00.0-0.00.40.30.3-0.3-0.70.6-0.2-0.3-0.30.20.10.3-0.10.1-0.20.2
Conditioned reinforcement - actives0.90.91.81.00.9-1.2-0.91.0-1.0-1.1-1.3-1.31.11.0-1.01.01.00.9-0.9-0.80.8-0.60.6-0.50.5
Conditioned reinforcement - inactives1.01.23.31.51.6-1.8-0.91.1-1.1-1.3-1.4-1.41.41.3-1.21.10.90.2-0.9-0.80.4-0.40.3-0.3-0.1
Conditioned locomotion0.30.41.01.00.7-0.8-0.60.8-0.8-0.6-0.7-0.70.60.7-0.5-0.00.10.30.10.4-0.80.6-0.61.0-0.8
Patch foraging indifference point 0 sec0.91.43.2-1.2-1.51.81.0-1.11.11.71.71.7-1.7-1.21.4-1.1-1.2-1.31.10.60.00.2-0.3-0.20.2
Patch foraging indifference point AUC0.50.62.00.90.9-1.4-0.20.2-0.2-0.7-0.9-0.90.90.2-0.5-0.0-0.0-0.40.20.5-1.00.9-0.91.3-1.4
Delay disc. indifference point, 0s delay1.41.52.51.01.4-1.6-1.21.2-1.2-1.5-1.5-1.51.61.4-1.61.31.31.3-1.2-1.00.8-0.60.7-0.30.3
Delay disc. indifference point, 16s delay0.10.10.5-0.2-0.1-0.40.6-0.30.3-0.4-0.4-0.40.4-0.0-0.10.00.10.2-0.00.2-0.50.4-0.30.7-0.5
Delay disc. indifference point, 2s delay0.50.51.7-1.0-0.70.41.3-1.11.10.70.50.5-0.5-0.90.5-0.6-0.7-0.90.70.6-0.40.7-0.60.5-0.5
Delay disc. indifference point, 24s delay1.41.45.1-1.7-1.61.12.3-1.71.71.21.01.0-1.0-1.21.3-0.9-1.0-0.80.90.6-0.60.6-0.40.2-0.2
Delay disc. indifference point, 4s delay0.20.20.80.30.4-0.90.10.1-0.1-0.5-0.7-0.70.60.5-0.70.40.3-0.1-0.2-0.20.10.0-0.00.0-0.0
Delay disc. indifference point, 8s delay0.20.21.3-0.8-0.40.01.1-1.11.10.2-0.0-0.0-0.0-0.40.2-0.1-0.2-0.40.20.1-0.10.3-0.10.2-0.1
Indifference point function ln k2.63.610.2-2.9-2.93.22.0-2.02.02.42.52.5-2.6-1.72.2-1.3-1.2-0.61.00.40.4-0.30.4-1.11.2
Indifference point function log k2.63.610.2-2.9-2.93.22.0-2.02.02.42.52.5-2.6-1.72.2-1.3-1.2-0.61.00.40.4-0.30.4-1.11.2
Patch foraging total patch changes 0 sec0.60.92.1-0.7-1.11.40.7-0.70.71.41.41.4-1.4-0.91.1-1.0-1.1-1.20.90.60.00.2-0.3-0.20.0
Patch foraging total patch changes 12 sec0.40.52.01.11.1-1.4-0.50.5-0.5-0.7-0.9-0.90.90.5-0.80.40.2-0.3-0.2-0.0-0.20.3-0.40.5-0.8
Patch foraging total patch changes 18 sec0.20.31.61.30.9-0.8-0.70.7-0.7-0.5-0.5-0.50.60.5-0.60.30.2-0.1-0.2-0.10.10.0-0.10.2-0.2
Patch foraging total patch changes 24 sec0.20.21.00.60.3-0.50.10.0-0.0-0.0-0.1-0.10.2-0.0-0.1-0.3-0.4-0.60.40.6-0.70.7-0.81.0-0.9
Patch foraging total patch changes 6 sec0.40.61.91.41.1-1.3-0.70.5-0.5-0.5-0.6-0.60.70.2-0.5-0.0-0.1-0.80.20.5-0.70.8-0.91.0-1.3
Patch foraging time to switch 0 sec1.62.44.41.92.1-1.9-2.12.0-2.0-1.8-1.7-1.71.71.5-1.91.41.51.2-1.4-1.10.8-0.80.7-0.40.5
Patch foraging water rate 0 sec0.81.22.4-1.3-1.51.21.5-1.31.31.21.11.1-1.2-1.11.1-1.1-1.1-0.91.10.9-0.80.8-0.70.6-0.8
Patch foraging water rate 12 sec0.40.71.10.70.6-0.7-0.20.5-0.5-0.7-1.0-1.00.80.8-0.71.00.90.8-0.9-1.01.0-0.90.9-0.90.7
Patch foraging water rate 18 sec0.40.51.9-0.6-0.50.70.3-0.10.10.20.10.1-0.20.00.20.50.50.8-0.6-0.91.3-1.11.2-1.41.3
Patch foraging water rate 24 sec0.10.10.30.30.3-0.5-0.00.2-0.2-0.4-0.6-0.60.40.3-0.40.30.30.2-0.2-0.2-0.0-0.00.10.0-0.2
Patch foraging water rate 6 sec0.20.21.1-0.8-0.80.51.0-0.70.70.40.30.3-0.5-0.40.4-0.3-0.30.20.30.2-0.30.2-0.10.1-0.3
Seeking ratio, delayed vs. immediate footshock0.60.71.1-0.5-0.70.90.5-0.50.50.91.01.0-0.9-0.60.8-1.0-1.0-0.41.01.0-0.80.9-0.90.8-0.7
Distance traveled before self-admin0.20.31.20.40.2-0.4-0.20.1-0.1-0.2-0.1-0.10.30.0-0.1-0.4-0.30.30.40.7-0.50.9-0.91.1-1.0
Distance traveled after self-admin4.85.410.43.23.2-2.9-3.12.9-2.9-2.8-2.6-2.62.82.8-2.81.92.02.0-1.8-1.20.7-0.70.50.10.1
Extensor digitorum longus weight3.112.117.94.24.2-4.2-4.03.7-3.7-4.2-4.2-4.24.23.8-3.83.63.63.2-3.4-2.82.2-2.22.1-1.31.2
Bone: elastic displacement0.50.51.0-0.4-0.50.20.7-0.80.80.50.60.6-0.6-0.50.4-0.8-0.8-0.80.80.9-1.00.9-0.90.9-1.0
Bone: elastic work1.72.23.5-1.6-1.51.21.7-1.91.91.41.51.5-1.4-1.51.4-1.5-1.5-1.51.51.5-1.51.4-1.31.2-1.2
Bone: endosteal estimation1.02.27.61.72.0-2.8-0.90.8-0.8-2.1-2.3-2.32.41.1-1.61.31.20.7-1.0-0.6-0.30.2-0.10.7-0.7
Bone: endosteal perimeter1.22.67.41.92.2-2.7-1.41.3-1.3-2.2-2.4-2.42.51.4-1.81.41.40.8-1.2-0.7-0.0-0.10.10.5-0.5
Epididymis fat weight3.78.510.92.93.1-3.0-2.93.1-3.1-3.2-3.1-3.13.33.1-3.13.23.12.9-3.1-2.92.6-2.52.4-2.21.7
Delta time in closed arm before/after self-admin0.40.40.80.70.5-0.6-0.90.7-0.7-0.8-0.7-0.70.80.7-0.60.50.60.7-0.5-0.30.1-0.20.20.2-0.1
Delta time in open arm before/after self-admin0.70.71.91.01.3-1.4-0.50.6-0.6-0.9-1.1-1.11.10.9-1.00.80.70.1-0.7-0.70.6-0.40.4-0.50.4
Diff in mean of infusions in LGA sessions0.30.31.00.30.10.2-0.60.5-0.50.0-0.0-0.00.10.10.00.40.40.4-0.4-0.71.0-0.90.8-1.00.8
Delay discount exponential model param0.60.63.11.30.9-0.4-1.81.4-1.4-0.5-0.3-0.30.30.8-0.50.40.50.3-0.5-0.40.4-0.50.3-0.40.3
Extinction: sum of active levers before priming2.12.14.81.01.4-0.9-1.21.2-1.2-1.1-1.1-1.11.21.2-1.21.61.51.4-1.6-1.82.0-1.71.6-2.02.2
Active lever presses in extinction session 61.51.52.01.11.2-0.9-1.41.4-1.4-1.2-1.1-1.11.21.3-1.41.31.31.3-1.3-1.21.2-1.21.1-1.01.2
Bone: final force0.30.41.30.40.7-1.2-0.10.1-0.1-0.9-1.0-1.01.00.7-1.00.70.70.4-0.6-0.50.2-0.20.2-0.1-0.0
Bone: final moment0.30.41.50.60.7-1.2-0.10.1-0.1-0.9-1.0-1.01.00.8-1.00.70.60.3-0.5-0.40.0-0.10.10.1-0.2
Food consumed during 24 hour testing period0.20.31.3-0.8-0.91.10.3-0.30.30.60.60.6-0.7-0.20.8-0.2-0.10.10.1-0.10.4-0.40.4-0.50.5
Glucose1.92.96.1-0.7-0.4-0.11.8-1.71.71.00.90.9-1.0-1.40.9-1.7-1.8-2.21.92.1-2.42.4-2.42.3-2.5
Heart weight0.81.12.31.21.5-1.3-1.21.2-1.2-1.2-1.2-1.21.31.1-1.21.11.00.7-1.0-0.90.7-0.70.6-0.60.6
Delay discount hyperbolic model param0.40.42.41.10.7-0.2-1.61.2-1.2-0.4-0.2-0.20.20.6-0.40.40.40.4-0.5-0.40.4-0.50.4-0.40.3
Intermittent access intake day 1-15 change0.60.62.20.90.7-1.1-0.40.3-0.3-0.5-0.5-0.50.50.7-0.8-0.2-0.2-0.60.30.7-1.01.0-1.11.3-1.5
Intermittent access intake escalation0.60.62.10.70.5-0.9-0.30.3-0.3-0.4-0.3-0.30.40.5-0.7-0.3-0.3-0.70.40.8-1.21.1-1.11.4-1.4
Intermittent access intake escalation 20.80.82.7-0.0-0.4-0.20.4-0.50.50.30.30.3-0.4-0.10.0-0.9-0.9-1.11.01.3-1.41.5-1.51.7-1.6
Intermitt. access day 1 inactive lever presses0.70.82.30.0-0.0-0.20.8-0.70.70.50.50.5-0.5-0.30.3-0.9-1.0-0.81.01.1-1.41.4-1.41.3-1.5
Intermitt. access day 15 inactive lever presses0.20.21.3-0.4-0.30.30.4-0.60.60.40.40.4-0.4-0.30.4-0.2-0.3-1.10.2-0.00.0-0.00.0-0.30.2
Intermitt. access escalation Index1.21.12.40.20.6-0.5-0.50.6-0.6-0.7-0.8-0.80.90.3-0.51.21.21.2-1.2-1.41.5-1.41.5-1.41.6
Intermittent access day 1 total infusions1.61.93.31.71.8-1.8-1.41.4-1.4-1.6-1.7-1.71.61.5-1.31.41.41.2-1.3-1.10.9-0.80.7-0.60.5
Intermittent access day 15 total infusions2.83.17.52.72.5-2.7-2.02.1-2.1-2.2-2.2-2.22.12.3-2.21.21.30.5-1.0-0.4-0.20.1-0.20.8-0.9
Intermittent access terminal intake (last 3 days)2.83.06.42.42.4-2.5-1.91.9-1.9-2.2-2.2-2.22.12.1-2.11.61.61.0-1.4-1.00.6-0.60.5-0.10.0
Intermittent access total infusions1.71.94.31.92.0-2.1-1.51.5-1.5-1.8-1.8-1.81.61.7-1.61.21.21.0-1.1-0.70.3-0.30.20.1-0.1
Intermittent access day 1 locomotion2.32.55.42.32.3-2.0-2.02.1-2.1-1.8-1.8-1.81.62.1-1.71.31.30.9-1.2-0.80.6-0.50.4-0.10.1
Intermittent access day 15 total locomotion0.91.02.61.61.4-1.4-1.31.3-1.3-1.2-1.1-1.11.01.4-1.20.50.60.3-0.5-0.0-0.30.3-0.30.7-0.7
Intermittent access total locomotion1.11.23.01.71.5-1.5-1.41.4-1.4-1.3-1.3-1.31.01.6-1.30.80.90.6-0.8-0.40.3-0.20.10.1-0.1
Intermittent access standard deviation2.12.35.62.41.9-2.2-1.71.7-1.7-1.7-1.4-1.41.42.0-1.90.40.5-0.1-0.30.5-1.21.0-1.11.8-1.8
Left kidney weight0.00.10.30.30.4-0.2-0.50.2-0.2-0.4-0.2-0.20.30.2-0.10.00.10.2-0.10.2-0.50.3-0.20.6-0.6
Right kidney weight0.00.10.20.20.3-0.2-0.20.3-0.3-0.3-0.1-0.10.10.3-0.20.00.10.2-0.10.2-0.40.2-0.20.4-0.4
Cocaine induced anxiety1.72.03.1-1.7-1.81.51.6-1.71.71.61.51.5-1.5-1.61.6-1.4-1.5-0.91.41.2-1.21.0-0.90.7-0.7
Post-drug Anxiety0.70.71.6-1.1-1.10.71.2-1.21.21.10.80.8-0.9-1.11.1-0.7-0.9-0.40.80.5-0.30.4-0.4-0.1-0.2
Baseline Anxiety0.60.61.41.11.2-1.1-0.80.8-0.8-0.8-0.9-0.90.90.9-0.90.80.60.3-0.6-0.60.7-0.40.3-0.40.1
Tail length2.16.211.81.41.2-0.7-2.02.0-2.0-1.8-1.8-1.82.22.0-1.82.82.73.0-2.9-3.23.4-3.33.3-3.43.3
Length with tail1.03.79.40.10.4-0.0-1.10.9-0.9-1.1-1.1-1.11.41.0-1.12.12.12.7-2.3-2.62.9-2.93.0-3.12.8
Length without tail0.92.14.7-0.40.4-0.4-0.80.6-0.6-1.0-1.1-1.11.00.4-0.71.71.72.2-1.8-2.02.1-2.12.1-2.11.9
Times rat made contact with spout0.91.02.0-1.2-1.31.31.4-1.31.31.31.31.3-1.2-0.81.1-0.9-0.9-0.90.80.5-0.20.2-0.2-0.20.0
Lifetime Intake2.52.86.72.42.4-2.6-1.81.8-1.8-2.2-2.2-2.22.02.0-1.91.51.50.9-1.3-0.90.4-0.40.30.0-0.0
Liver weight, left0.30.41.4-0.3-0.10.20.00.0-0.0-0.2-0.3-0.30.20.6-0.60.60.70.9-0.7-0.91.0-1.11.1-1.21.0
Liver weight, right1.01.63.00.60.9-0.8-0.80.7-0.7-1.3-1.3-1.31.41.3-1.51.51.51.7-1.5-1.51.2-1.41.5-1.21.1
Locomotor activity0.71.22.51.51.6-1.3-1.61.5-1.5-1.2-1.2-1.21.11.1-0.91.00.90.6-0.9-0.70.6-0.60.5-0.30.3
Locomotor testing distance2.64.39.73.12.9-2.9-2.62.6-2.6-2.4-2.5-2.52.42.4-2.31.81.71.1-1.6-1.20.8-0.70.5-0.10.0
Locomotor testing rearing2.64.010.83.32.9-2.8-2.72.7-2.7-2.3-2.3-2.32.22.4-2.21.51.40.7-1.3-0.70.3-0.30.10.3-0.6
Locomotion in novel chamber1.11.45.61.00.7-1.00.10.2-0.2-0.2-0.3-0.30.00.2-0.2-0.9-0.9-0.81.01.5-1.81.9-2.02.3-2.4
Locomotion in novel chamber post-restriction0.40.50.7-0.3-0.50.50.8-0.60.60.70.70.7-0.7-0.50.8-0.8-0.8-0.40.80.8-0.60.7-0.80.7-0.8
Fecal boli incidents, locomotor time 10.30.30.9-0.8-0.90.90.4-0.60.60.60.60.6-0.7-0.50.5-0.5-0.4-0.50.40.3-0.10.1-0.10.10.1
Change in fecal boli incidents, locomotor task0.80.71.8-1.2-1.00.71.1-1.21.20.90.80.8-0.8-1.31.1-0.7-0.8-0.90.70.5-0.60.4-0.40.1-0.1
Time >=10cm from walls, locomotor time 10.20.20.5-0.6-0.60.70.4-0.50.50.60.70.7-0.7-0.70.7-0.4-0.4-0.10.40.20.00.1-0.0-0.10.2
Bouts of movement, locomotor time 10.50.51.8-1.3-1.21.11.2-1.01.00.80.70.7-0.6-0.60.6-0.3-0.4-0.30.3-0.00.3-0.20.3-0.50.5
Total resting periods, locomotor time 11.41.54.2-2.1-1.91.81.8-1.61.61.51.41.4-1.2-1.31.3-0.9-0.9-0.90.80.4-0.00.10.0-0.30.3
Rest time, locomotor task time 10.80.91.9-1.0-1.11.00.9-0.90.91.01.01.0-0.9-1.01.0-1.0-0.9-1.40.90.9-0.80.8-0.70.6-0.4
Distance moved, locomotor task time 11.11.23.01.71.6-1.5-1.11.3-1.3-1.2-1.2-1.21.11.4-1.30.90.91.1-0.9-0.70.6-0.50.4-0.20.1
Vertical activity count, locomotor time 11.41.53.41.81.7-1.5-1.51.5-1.5-1.3-1.2-1.21.21.6-1.61.11.00.9-1.0-0.80.8-0.60.5-0.40.2
Time >=10cm from walls, locomotor time 20.60.71.4-1.2-1.11.20.8-1.01.01.01.01.0-0.9-0.90.9-0.7-0.7-0.30.70.5-0.20.3-0.30.1-0.0
Bouts of movement, locomotor time 21.11.12.4-1.5-1.51.31.6-1.51.51.21.21.2-1.1-1.11.0-0.8-0.9-1.10.80.5-0.30.3-0.2-0.10.2
Total resting periods, locomotor time 20.60.71.6-1.3-1.21.11.2-1.11.10.90.90.9-0.9-0.90.7-0.5-0.5-0.90.50.2-0.00.00.0-0.30.4
Rest time, locomotor task time 20.70.81.8-0.9-1.31.30.6-0.30.31.11.11.1-1.2-1.01.0-0.9-0.9-0.90.80.8-0.60.5-0.50.3-0.2
Distance moved, locomotor task time 21.31.53.61.91.8-1.8-1.31.4-1.4-1.4-1.4-1.41.41.7-1.60.90.90.8-0.8-0.40.2-0.1-0.00.4-0.5
Vertical activity count, locomotor time 20.50.61.21.01.1-1.1-0.90.7-0.7-0.9-0.9-0.91.01.1-1.10.70.70.7-0.6-0.50.4-0.30.2-0.00.1
Light reinforcement 11.12.04.32.12.0-2.0-1.61.7-1.7-1.6-1.6-1.61.51.6-1.81.21.20.7-1.1-0.80.6-0.50.4-0.20.1
Light reinforcement 20.10.10.3-0.10.1-0.50.3-0.40.4-0.2-0.4-0.40.20.2-0.20.0-0.0-0.10.10.1-0.50.3-0.30.3-0.4
Bone: marrow area1.02.17.51.72.0-2.7-1.00.8-0.8-2.1-2.3-2.32.41.1-1.61.31.20.6-1.0-0.6-0.30.1-0.10.7-0.7
Bone: maximum diameter0.20.31.10.20.5-1.00.3-0.30.3-0.6-0.7-0.70.80.2-0.20.0-0.0-0.40.10.4-0.90.8-0.71.0-0.9
Bone: maximum force0.20.41.50.50.7-1.2-0.10.1-0.1-0.9-1.0-1.01.00.6-0.90.60.60.3-0.5-0.4-0.0-0.00.10.1-0.2
Bone: maximum moment0.30.51.90.70.8-1.4-0.10.1-0.1-1.0-1.0-1.01.10.7-1.00.60.50.2-0.4-0.3-0.20.1-0.10.3-0.4
Mean time between licks in bursts2.13.04.61.41.7-1.4-2.12.1-2.1-1.8-1.8-1.81.71.7-1.51.81.92.2-1.9-1.71.5-1.61.6-1.21.2
Mean num. licks in bursts0.10.10.4-0.2-0.30.30.3-0.10.10.10.10.1-0.1-0.0-0.10.20.20.6-0.2-0.30.5-0.40.5-0.50.5
Cd content in liver1.01.11.91.21.3-1.1-1.11.3-1.3-1.2-1.2-1.21.20.9-1.41.11.10.4-1.1-1.00.9-0.80.8-0.60.6
Co content in liver0.20.20.60.00.1-0.3-0.10.1-0.1-0.5-0.6-0.60.60.2-0.60.60.60.8-0.6-0.60.4-0.50.6-0.40.4
Cu content in liver1.92.34.3-1.9-2.02.02.1-2.02.01.91.91.9-1.9-1.61.6-1.3-1.4-0.91.20.8-0.60.5-0.4-0.00.1
Fe content in liver0.30.41.4-0.10.00.1-0.30.3-0.3-0.2-0.2-0.20.20.4-0.50.60.60.7-0.7-0.91.0-1.01.0-1.21.2
K content in liver0.50.51.2-0.2-0.20.4-0.50.3-0.3-0.3-0.2-0.20.20.5-0.30.60.71.1-0.8-0.81.0-1.01.1-1.01.0
Mg content in liver0.10.10.60.60.3-0.0-0.60.5-0.5-0.10.10.1-0.10.8-0.2-0.1-0.00.20.00.2-0.20.1-0.20.3-0.3
Mn content in liver0.50.62.5-1.0-1.21.60.0-0.10.11.01.21.2-1.2-0.81.1-0.6-0.5-0.10.40.20.3-0.20.2-0.40.4
Na content in liver0.10.10.3-0.4-0.2-0.10.5-0.60.60.00.10.1-0.1-0.30.3-0.3-0.30.30.30.4-0.60.5-0.50.6-0.6
Rb content in liver0.40.51.40.70.9-1.2-0.40.5-0.5-0.9-1.0-1.01.00.9-0.80.70.60.5-0.6-0.40.2-0.20.20.1-0.1
Se content in liver1.31.62.1-1.4-1.41.21.4-1.41.41.31.31.3-1.3-1.21.3-1.3-1.3-1.31.31.2-1.11.0-1.00.8-0.8
Sr content in liver1.31.22.21.01.2-1.4-0.60.6-0.6-1.4-1.5-1.51.50.6-1.11.31.21.3-1.2-1.20.9-0.80.9-0.70.7
Zn content in liver0.20.20.80.4-0.00.30.1-0.10.10.50.50.5-0.50.00.3-0.5-0.5-0.90.50.5-0.30.4-0.50.4-0.3
Bone: minimum diameter0.71.33.81.01.3-2.0-0.30.4-0.4-1.6-1.9-1.91.91.2-1.41.21.10.9-1.0-0.70.0-0.10.20.2-0.3
Time in familiar zone, hab. session 10.30.31.01.00.7-0.6-0.80.9-0.9-0.3-0.1-0.10.20.7-0.6-0.1-0.0-0.20.10.3-0.30.3-0.40.5-0.6
Time in novel zone, hab. session 10.50.51.6-1.3-1.00.81.1-1.11.10.60.30.3-0.4-1.11.0-0.2-0.3-0.10.2-0.10.2-0.20.3-0.50.3
Total zone transitions, hab. session 14.46.213.03.53.4-3.1-3.63.4-3.4-2.9-2.6-2.62.63.0-3.12.02.11.8-1.9-1.30.9-0.90.60.00.0
Total locomotion distance, hab. session 10.91.23.81.71.4-1.0-1.91.9-1.9-1.0-0.7-0.70.71.6-1.30.70.80.6-0.8-0.50.6-0.50.3-0.30.2
Locomotion velocity, hab. session 10.81.23.61.71.5-1.1-1.91.8-1.8-1.0-0.8-0.80.81.5-1.30.70.70.4-0.7-0.40.5-0.40.2-0.10.1
Time in familiar zone, hab. session 20.10.10.4-0.4-0.40.6-0.10.2-0.20.30.20.2-0.2-0.30.5-0.0-0.0-0.1-0.0-0.20.5-0.30.4-0.50.6
Time in novel zone, hab. session 20.50.51.0-0.4-0.40.20.9-1.01.00.60.60.6-0.6-0.70.4-0.7-0.8-0.80.80.7-0.90.8-0.80.7-0.8
Total zone transitions, hab. session 22.53.36.72.12.2-2.1-2.62.3-2.3-2.1-1.9-1.91.92.0-2.31.71.81.6-1.7-1.41.1-1.11.0-0.60.5
Total locomotion distance, hab. session 20.71.03.01.31.3-1.0-1.71.5-1.5-1.0-0.8-0.80.81.2-1.20.80.80.6-0.8-0.60.6-0.60.4-0.30.3
Locomotion velocity, hab. session 20.71.03.11.31.3-1.0-1.71.5-1.5-1.0-0.8-0.80.81.3-1.20.80.80.7-0.8-0.60.5-0.50.4-0.20.2
Novel to familiar place preference ratio0.10.10.40.40.3-0.3-0.0-0.10.1-0.0-0.0-0.00.1-0.20.1-0.2-0.2-0.50.30.4-0.40.5-0.50.5-0.6
Novelty place preference0.00.00.10.10.2-0.10.1-0.20.20.0-0.0-0.00.1-0.30.2-0.1-0.1-0.30.10.1-0.00.2-0.20.1-0.3
Time in novel zone, NPP test0.00.00.10.10.1-0.10.1-0.20.20.1-0.1-0.10.1-0.30.20.0-0.1-0.20.0-0.00.10.0-0.0-0.1-0.0
Total zone transitions, NPP test3.14.49.62.82.8-2.6-3.12.9-2.9-2.4-2.1-2.12.22.4-2.71.81.91.5-1.7-1.31.0-1.00.8-0.30.3
Total locomotion distance, NPP test0.40.62.31.31.1-0.8-1.51.4-1.4-0.6-0.3-0.30.40.7-0.80.10.2-0.2-0.10.2-0.30.3-0.40.6-0.6
Locomotion velocity, NPP test0.40.51.31.00.8-0.6-1.11.0-1.0-0.30.00.00.00.3-0.5-0.3-0.3-0.60.30.7-0.80.7-0.91.0-1.0
Intraocular pressure0.60.82.41.31.5-1.5-0.80.5-0.5-0.7-0.9-0.90.80.5-0.5-0.0-0.1-0.90.30.6-0.71.0-1.11.2-1.0
Delta distance traveled before/after self-admin4.95.38.72.82.9-2.5-2.82.7-2.7-2.5-2.4-2.42.42.7-2.72.32.31.7-2.2-2.01.6-1.71.6-1.41.5
Delta ambulatory time before/after self-admin3.43.76.62.42.6-2.1-2.42.3-2.3-2.0-2.0-2.01.92.2-2.21.91.91.3-1.8-1.71.4-1.51.3-1.21.4
Parametrial fat weight11.522.428.94.14.7-4.8-4.04.2-4.2-5.0-5.4-5.45.35.0-5.05.45.25.1-5.2-5.14.6-4.44.3-3.83.7
Pavlov. Cond. lever latency0.91.22.81.31.4-1.7-0.91.0-1.0-1.6-1.6-1.61.60.9-1.01.01.01.0-0.9-0.5-0.1-0.10.10.4-0.3
Pavlov. Cond. magazine entry latency1.72.25.7-2.4-2.22.31.8-1.71.71.91.81.8-1.8-1.61.6-0.9-1.0-0.60.80.20.4-0.30.4-1.01.0
Pavlov. Cond. change in total contacts1.61.73.2-1.0-1.31.51.1-1.21.21.71.81.8-1.7-1.11.2-1.5-1.5-1.61.41.1-0.70.8-0.90.4-0.6
Pavlov. Cond. index score0.81.13.1-1.5-1.51.71.0-0.90.91.41.41.4-1.4-0.91.0-0.6-0.6-0.40.5-0.00.6-0.50.5-1.00.9
Pavlov. Cond. latency score0.91.23.4-1.7-1.61.81.0-0.90.91.41.41.4-1.4-0.90.9-0.5-0.6-0.30.4-0.20.7-0.60.6-1.21.1
Pavlov. Cond. lever contacts0.50.51.6-0.7-0.81.20.3-0.40.41.11.31.3-1.2-0.40.6-0.6-0.7-0.60.50.20.3-0.20.1-0.60.4
Pavlov. Cond. magazine entry number1.01.22.61.51.5-1.6-1.31.2-1.2-1.5-1.4-1.41.41.3-1.20.91.00.9-0.8-0.4-0.0-0.10.10.4-0.3
Pavlov. Cond. intertrial magazine entries1.92.46.72.62.3-2.4-1.71.9-1.9-1.9-1.8-1.81.81.6-1.91.21.10.5-1.0-0.60.2-0.1-0.00.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.81.02.9-1.4-1.51.71.0-0.90.91.41.41.4-1.4-0.90.9-0.7-0.7-0.50.50.10.5-0.30.3-0.80.7
Pavlov. Cond. response bias0.81.02.6-1.3-1.31.61.0-1.01.01.51.51.5-1.4-1.01.0-0.8-0.9-0.80.70.30.2-0.10.1-0.60.5
Pavlov. Cond. lever latency2.22.94.81.11.2-1.2-1.51.6-1.6-1.7-1.7-1.71.81.8-1.81.92.02.2-2.0-1.91.7-1.81.8-1.61.5
Pavlov. Cond. magazine entry latency1.01.11.9-0.9-1.01.11.1-1.31.31.21.21.2-1.2-1.31.4-1.1-1.1-1.11.11.0-0.80.8-0.80.6-0.5
Pavlov. Cond. change in total contacts1.01.42.5-1.2-1.11.11.4-1.41.41.31.21.2-1.2-1.61.5-1.2-1.2-1.21.21.1-0.91.0-0.90.7-0.7
Pavlov. Cond. index score1.72.13.4-0.7-0.90.81.3-1.31.31.31.31.3-1.3-1.41.5-1.6-1.7-1.81.71.7-1.71.7-1.81.6-1.6
Pavlov. Cond. latency score2.02.53.8-0.7-0.90.81.4-1.51.51.41.31.3-1.3-1.51.5-1.8-1.8-2.01.91.9-1.91.9-1.91.9-1.8
Pavlov. Cond. lever contacts0.81.12.0-0.4-0.60.50.8-0.80.81.00.90.9-1.0-1.21.1-1.2-1.2-1.41.21.2-1.11.2-1.21.1-1.1
Pavlov. Cond. magazine entry number1.01.21.70.80.9-0.8-1.11.3-1.3-1.1-1.0-1.01.01.2-1.21.21.21.3-1.2-1.11.0-1.11.0-0.90.8
Pavlov. Cond. intertrial magazine entries1.01.31.61.11.2-1.2-1.11.1-1.1-1.2-1.3-1.31.21.0-1.21.31.21.1-1.2-1.21.1-1.01.0-0.90.9
Pavlov. Cond. lever-magazine prob. diff.1.72.23.4-0.8-0.90.91.4-1.51.51.41.31.3-1.3-1.51.5-1.7-1.7-1.81.71.7-1.71.7-1.71.6-1.5
Pavlov. Cond. response bias1.01.42.3-0.6-0.80.91.0-1.11.11.21.21.2-1.3-1.31.3-1.4-1.4-1.51.41.3-1.21.2-1.31.1-1.0
Time in closed arm before self-admin0.40.41.7-0.8-0.40.50.7-0.70.70.40.30.3-0.2-0.60.50.30.10.5-0.2-0.71.0-0.80.8-1.31.1
Time in closed arm after self-admin0.10.10.5-0.6-0.70.40.5-0.60.60.20.30.3-0.2-0.60.6-0.2-0.20.40.20.1-0.10.1-0.00.1-0.1
Time in open arm before self-admin1.31.42.5-0.4-0.70.90.8-0.60.61.11.21.2-1.1-0.80.8-1.5-1.4-1.41.41.6-1.61.5-1.51.6-1.4
Time in open arm after self-admin0.70.71.91.41.4-1.2-0.50.7-0.7-0.4-0.5-0.50.40.7-0.7-0.3-0.3-1.20.40.7-0.81.0-1.11.2-1.1
Bone: periosteal estimation0.30.73.00.61.0-1.70.1-0.20.2-1.2-1.4-1.41.40.4-0.80.50.4-0.0-0.3-0.0-0.70.6-0.50.9-0.9
Bone: periosteal perimeter0.20.31.20.20.5-1.10.3-0.10.1-0.7-1.0-1.01.00.1-0.40.30.2-0.1-0.10.1-0.60.5-0.40.6-0.6
Bone: post-yield work0.60.81.20.70.6-0.7-1.00.9-0.9-0.8-0.9-0.90.90.5-0.81.01.00.9-1.0-1.11.1-1.01.0-1.00.9
Progressive ratio test 1 active lever presses1.21.21.81.01.1-1.2-0.80.9-0.9-1.3-1.3-1.31.31.2-1.11.31.30.9-1.2-1.21.0-1.01.0-0.90.8
Progressive ratio test 1 breakpoint1.91.92.61.31.5-1.4-1.11.2-1.2-1.5-1.6-1.61.51.5-1.31.61.61.1-1.5-1.51.4-1.31.3-1.21.2
Progressive ratio test 1 inactive lever presses0.70.82.20.81.3-1.5-0.50.5-0.5-1.3-1.3-1.31.11.1-1.01.00.90.6-0.8-0.60.2-0.20.3-0.10.2
Progressive ratio test 2 active lever presses0.80.91.61.11.1-1.1-1.01.0-1.0-1.1-1.1-1.11.01.2-1.21.01.00.7-0.9-0.80.7-0.60.6-0.40.6
Progressive ratio test 2 breakpoint0.60.71.20.91.0-0.9-0.80.9-0.9-0.9-0.9-0.90.71.1-1.00.80.80.5-0.8-0.70.7-0.60.6-0.50.6
Progressive ratio test 2 inactive lever presses1.31.54.81.71.7-2.2-1.01.0-1.0-1.6-1.6-1.61.51.6-1.71.21.10.5-1.0-0.80.4-0.30.2-0.1-0.1
Incentive Sensitization - Responses0.20.20.40.50.6-0.6-0.50.5-0.5-0.5-0.5-0.50.30.6-0.60.50.50.5-0.4-0.40.2-0.30.3-0.20.4
Incentive Sensitization - Breakpoint0.20.20.40.50.6-0.6-0.50.5-0.5-0.5-0.5-0.50.30.6-0.60.40.40.5-0.4-0.30.2-0.30.2-0.20.3
Sum of active levers in priming session hrs 5-61.21.23.60.30.4-0.0-0.80.7-0.7-0.4-0.5-0.50.40.5-0.51.11.01.0-1.1-1.41.9-1.61.6-1.91.9
Progressive ratio0.20.20.80.80.8-0.9-0.50.4-0.4-0.5-0.6-0.60.60.4-0.40.10.10.4-0.00.1-0.20.4-0.40.5-0.6
Food seeking constrained by brief footshock0.20.20.6-0.7-0.70.50.5-0.60.60.50.50.5-0.3-0.80.5-0.5-0.4-0.40.40.4-0.50.4-0.30.3-0.3
Seeking ratio, punishment vs. effort0.50.61.7-1.3-1.31.30.8-0.80.80.91.01.0-1.0-1.00.8-0.5-0.5-0.50.40.2-0.1-0.10.1-0.30.3
Retroperitoneal fat weight0.10.21.00.30.6-1.00.3-0.20.2-0.6-0.6-0.60.60.5-0.90.30.20.2-0.20.0-0.40.3-0.30.5-0.6
Reaction time number correct0.20.30.60.60.6-0.3-0.40.8-0.8-0.5-0.5-0.50.40.6-0.50.60.60.6-0.6-0.60.7-0.70.6-0.60.5
Reaction time mean minus median1.21.63.3-1.0-1.00.51.3-1.41.41.21.01.0-1.1-1.31.2-1.3-1.4-1.81.41.3-1.21.3-1.40.9-1.3
Reaction time mean minus median AUC0.40.61.2-0.6-0.60.10.9-0.90.90.70.40.4-0.5-0.80.8-0.7-0.8-1.10.80.7-0.70.8-0.90.6-1.0
Reaction time num false alarms1.62.23.5-1.6-1.61.31.7-1.81.81.61.51.5-1.6-1.51.9-1.5-1.6-1.81.51.3-1.11.1-1.10.7-0.8
Reaction time num false alarms AUC1.21.72.6-1.4-1.31.11.5-1.61.61.41.31.3-1.4-1.21.6-1.3-1.4-1.51.41.2-1.11.1-1.10.8-0.8
Reaction time trials correct on left0.20.30.60.60.6-0.3-0.40.8-0.8-0.5-0.5-0.50.40.6-0.50.60.60.6-0.6-0.60.7-0.70.6-0.60.5
Reaction time trials on left0.20.30.50.60.5-0.3-0.40.7-0.7-0.5-0.5-0.50.40.6-0.50.60.60.6-0.6-0.60.6-0.60.6-0.60.4
Reaction time mean0.40.51.1-0.7-0.70.40.6-0.70.70.80.70.7-0.8-0.70.8-0.8-0.8-1.00.80.8-0.70.7-0.80.4-0.7
Reaction time mean AUC0.91.22.1-0.9-1.00.70.9-1.01.01.11.01.0-1.1-1.11.2-1.2-1.2-1.41.21.2-1.11.1-1.10.8-1.1
Median of all reaction times0.10.20.4-0.4-0.40.20.2-0.30.30.40.40.4-0.4-0.30.5-0.5-0.5-0.60.50.5-0.50.5-0.50.3-0.5
Reaction time omissions0.10.10.8-0.10.3-0.90.1-0.30.3-0.5-0.7-0.70.50.1-0.20.30.20.0-0.1-0.1-0.10.2-0.20.2-0.5
Reaction time false alarm rate1.31.82.8-1.4-1.41.01.4-1.71.71.41.31.3-1.4-1.41.6-1.4-1.4-1.61.41.2-1.21.2-1.10.8-0.8
Reaction time premature initiation rate0.60.82.3-1.4-1.41.50.6-0.90.91.21.11.1-1.2-1.21.0-0.6-0.6-0.20.50.10.3-0.20.3-0.50.6
Reaction time premature initiations0.30.51.6-1.0-1.01.30.3-0.40.40.80.70.7-0.9-0.80.6-0.2-0.20.20.1-0.20.6-0.60.6-0.70.7
Std. dev. reaction times1.82.53.9-1.7-1.61.11.6-1.81.81.71.51.5-1.6-1.91.8-1.7-1.7-2.01.71.5-1.31.4-1.40.9-1.3
Reaction time trials completed0.20.30.50.60.5-0.3-0.40.7-0.7-0.5-0.5-0.50.40.6-0.50.60.60.6-0.6-0.60.6-0.60.6-0.60.4
Reaction time trials AUC0.20.20.40.50.4-0.2-0.30.6-0.6-0.4-0.4-0.40.30.5-0.40.50.50.6-0.5-0.60.6-0.60.6-0.60.4
Run reversals in cocaine runway, females0.10.10.3-0.2-0.10.20.3-0.40.40.30.30.3-0.5-0.40.4-0.3-0.3-0.50.30.3-0.30.3-0.30.00.1
Run reversals in cocaine runway, males1.71.65.22.32.0-1.8-1.71.7-1.7-1.2-1.0-1.01.01.8-1.60.40.40.2-0.30.2-0.30.6-0.81.1-1.1
Latency to leave start box in cocaine runway0.30.30.9-0.9-0.70.60.9-0.90.90.40.40.4-0.3-0.70.6-0.2-0.2-0.10.10.0-0.2-0.00.1-0.20.1
Latency to leave start box in cocaine runway, F0.30.31.0-1.0-0.90.70.8-0.80.80.40.30.3-0.2-0.50.40.10.1-0.1-0.2-0.40.3-0.60.7-0.80.7
Latency to leave start box in cocaine runway, M0.20.20.90.30.5-0.5-0.30.3-0.3-0.5-0.5-0.50.50.2-0.30.40.41.0-0.4-0.30.1-0.20.2-0.10.1
Std. dev. time between licks in bursts0.70.91.80.80.9-0.8-1.21.1-1.1-0.9-1.0-1.01.01.0-0.80.91.01.3-0.9-0.80.8-0.80.8-0.60.6
Total sessions with >9 infusions1.71.83.41.31.6-1.8-1.11.2-1.2-1.8-1.9-1.91.71.5-1.41.51.50.9-1.4-1.20.6-0.80.9-0.60.7
Short access day 1 total inactive lever presses0.10.10.50.40.7-0.7-0.30.1-0.1-0.4-0.4-0.40.40.2-0.20.30.2-0.3-0.2-0.2-0.10.0-0.1-0.0-0.1
Short access day 10 total inactive lever presses0.00.00.1-0.3-0.30.30.2-0.30.30.10.30.3-0.40.1-0.1-0.1-0.0-0.20.0-0.0-0.2-0.10.1-0.10.1
Short access day 1 total infusions1.41.54.51.91.8-2.1-1.31.3-1.3-1.6-1.5-1.51.51.3-1.30.70.7-0.2-0.5-0.1-0.50.4-0.50.9-0.9
Short access day 10 total infusions1.11.23.11.51.7-1.8-1.01.1-1.1-1.4-1.5-1.51.31.1-1.01.11.00.6-0.9-0.70.4-0.40.3-0.30.2
Short access total infusions2.12.47.02.42.4-2.6-1.51.6-1.6-2.0-2.1-2.11.91.7-1.71.21.10.3-1.0-0.60.00.0-0.10.4-0.3
Short access day 1 locomotion0.40.41.51.01.1-1.2-0.50.4-0.4-0.7-0.8-0.80.60.7-0.60.20.2-0.4-0.10.2-0.40.5-0.60.7-0.6
Short access day 10 total locomotion0.80.92.51.61.4-1.3-1.31.2-1.2-1.0-0.9-0.90.91.5-1.20.40.4-0.2-0.30.1-0.20.3-0.40.7-0.6
Short access total locomotion0.60.61.81.31.4-1.1-0.91.0-1.0-0.9-0.9-0.90.71.2-0.90.40.40.0-0.30.0-0.30.2-0.30.6-0.3
One hour access (0.3 mA shock)1.21.43.31.51.4-1.8-1.21.3-1.3-1.4-1.6-1.61.41.5-1.61.11.11.0-1.0-0.80.6-0.40.4-0.10.1
Compulsive drug intake0.40.41.1-0.9-1.01.00.6-0.50.50.80.80.8-0.6-0.70.6-0.4-0.40.50.30.00.3-0.30.3-0.40.5
One hour access (shock baseline)1.51.73.71.71.7-1.9-1.31.4-1.4-1.7-1.8-1.81.51.6-1.61.21.20.6-1.1-0.80.4-0.40.4-0.0-0.0
Social response proportion1.31.45.7-1.0-0.40.70.2-0.20.20.20.10.1-0.3-0.50.10.90.81.2-1.0-1.62.1-1.91.9-2.42.2
Social responses2.53.24.21.82.1-1.7-1.92.0-2.0-1.7-1.8-1.81.71.8-1.61.91.81.6-1.8-1.92.0-1.81.6-1.61.5
Social time1.82.43.61.31.5-1.2-1.71.6-1.6-1.3-1.4-1.41.21.3-1.31.71.61.3-1.7-1.81.9-1.71.6-1.81.6
Soleus weight3.911.319.32.22.3-1.7-3.53.3-3.3-3.1-3.0-3.03.13.1-3.03.73.84.4-3.9-3.83.9-3.93.9-3.43.5
Bone: stiffness2.33.65.11.31.5-1.6-1.51.7-1.7-1.9-2.0-2.02.11.8-2.12.22.22.2-2.2-2.12.0-1.91.9-1.71.6
Tibialis anterior weight4.314.722.34.24.1-3.6-4.74.4-4.4-4.1-4.0-4.04.14.0-3.94.04.03.7-3.9-3.63.4-3.23.1-2.62.4
Time to tail flick, vehicle, before self-admin0.60.62.10.10.20.1-0.40.6-0.6-0.4-0.2-0.20.40.6-0.50.90.80.4-0.9-1.11.2-1.31.3-1.31.5
Time to tail flick, vehicle, after self-admin0.10.10.30.40.6-0.6-0.20.2-0.2-0.3-0.4-0.40.40.4-0.30.20.20.2-0.2-0.20.2-0.00.0-0.0-0.1
Time to tail flick, test, before self-admin1.51.54.2-1.7-1.72.01.1-1.21.21.71.61.6-1.7-1.21.4-1.0-1.0-0.80.90.40.2-0.10.1-0.80.6
Time to tail flick, test, after self-admin0.40.41.3-0.9-0.61.10.4-0.50.50.80.90.9-0.8-0.50.6-0.3-0.30.30.2-0.00.6-0.30.3-0.90.9
Delta time to tail flick, vehicle, before/after SA0.50.52.00.70.7-1.0-0.20.2-0.2-0.4-0.5-0.50.40.3-0.3-0.3-0.3-0.10.40.7-0.91.0-1.01.2-1.4
Delta time to tail flick, test, before/after SA0.80.71.51.21.2-1.1-1.01.0-1.0-1.1-0.9-0.91.01.0-1.00.60.70.8-0.6-0.30.1-0.00.00.3-0.0
Tibia length0.51.33.8-1.9-1.71.51.4-1.31.30.70.50.5-0.5-0.60.50.30.30.9-0.4-0.91.1-1.31.5-1.71.6
Ambulatory time before self-admin0.20.20.9-0.0-0.20.00.2-0.20.20.10.20.2-0.2-0.30.2-0.5-0.4-0.30.50.7-0.90.8-0.80.9-0.9
Ambulatory time after self-admin3.33.65.92.32.3-2.0-2.42.3-2.3-2.1-2.0-2.02.22.1-2.21.81.91.9-1.8-1.51.3-1.21.1-0.80.9
Bone: tissue strength0.20.20.70.10.0-0.40.4-0.60.60.00.10.1-0.1-0.0-0.2-0.3-0.4-0.40.40.5-0.70.7-0.70.8-0.8
Total heroin consumption1.51.75.30.30.5-0.1-1.21.0-1.0-0.5-0.6-0.60.50.7-0.61.41.30.6-1.4-1.82.3-2.12.0-2.32.2
Bone: trabecular number0.30.51.8-0.1-0.10.3-0.40.4-0.40.0-0.1-0.10.1-0.10.40.60.50.4-0.6-0.91.3-1.11.1-1.41.2
Bone: trabecular spacing0.10.20.80.20.3-0.40.3-0.10.1-0.2-0.1-0.10.10.1-0.6-0.2-0.2-0.00.20.5-0.80.6-0.60.9-0.7
Bone: trabecular thickness0.10.20.30.10.1-0.3-0.2-0.00.0-0.3-0.5-0.50.40.1-0.00.50.50.5-0.5-0.60.5-0.50.5-0.50.4
Bone: trabecular tissue density2.12.94.0-1.6-1.61.42.0-1.91.91.71.91.9-1.8-1.51.5-1.9-1.8-1.71.81.8-1.91.7-1.61.5-1.3
Water consumed over 24 hours2.32.86.8-2.6-2.52.62.3-2.22.22.02.02.0-2.0-1.71.7-1.1-1.1-0.90.90.40.0-0.10.3-0.70.6
Number of responses in last shaping day0.30.31.21.10.8-0.8-0.80.7-0.7-0.4-0.3-0.30.10.5-0.4-0.1-0.1-0.40.20.4-0.50.6-0.70.6-0.8