Hub : Genes

LOC102547233

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC102547233 0.82 0.06 2.8e-16 0.46 0.42 0.43 0.44 1.1e-12 2.3e-11 1.2e-11 5.2e-12
2 OFC gene expression LOC102547233 0.39 0.13 1.1e-04 0.16 0.07 0.07 0.12 1.6e-04 8.2e-03 1.1e-02 1.1e-03
3 Brain gene expression LOC102547233 0.4 0.09 0.0e+00 0.37 0.34 0.35 0.14 2.4e-36 2.4e-32 5.4e-34 8.2e-13
4 LHb gene expression LOC102547233 0.36 0.13 7.7e-05 0.06 0.15 0.15 0.11 1.3e-02 2.2e-04 2.2e-04 1.4e-03
5 Brain alternative TSS XR_594922.2 0.25 0.1 3.7e-11 0.11 0.11 0.12 0.07 3.4e-10 1.4e-10 1.5e-11 5.1e-07
6 BLA gene expression LOC102547233 0.6 0.1 0.0e+00 0.37 0.33 0.35 0.37 7.6e-21 2.1e-18 2.3e-19 5.8e-21
7 PL gene expression LOC102547233 0.66 0.08 0.0e+00 0.42 0.44 0.46 0.31 2.1e-49 6.2e-53 3.0e-56 2.1e-34
8 NAcc gene expression LOC102547233 0.16 0.06 1.2e-14 0.14 0.14 0.13 0.15 4.2e-16 2.1e-16 7.8e-15 1.3e-16
9 Brain alternative TSS XR_005490522.1 0.23 0.1 3.2e-11 0.1 0.11 0.12 0.07 3.9e-09 1.8e-10 3.8e-11 2.7e-07
10 pVTA gene expression LOC102547233 0.33 0.11 1.2e-10 0.23 0.24 0.24 0.23 2.4e-10 6.6e-11 6.7e-11 3.1e-10
11 PL alternative TSS XR_005490522.1 0.1 0.06 1.9e-05 0.05 0.03 0.07 0.03 2.8e-06 1.0e-04 9.6e-08 1.2e-04
12 PL alternative TSS XR_594922.2 0.08 0.05 1.3e-04 0.03 0.02 0.05 0.03 5.1e-04 1.1e-03 8.5e-06 6.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.20.9-0.1-0.1-0.20.8-0.90.1-0.10.21.0-0.30.4-0.5
Area under the delay curve1.51.64.3-1.0-1.0-1.0-0.01.51.1-1.61.1-2.12.0-0.60.3
BMI with tail0.41.36.2-0.5-0.5-0.7-2.51.20.30.20.6-1.7-1.5-0.80.8
BMI without tail0.81.66.9-0.5-0.5-0.7-2.01.90.6-0.61.0-2.60.4-1.00.8
Body weight0.31.22.8-0.6-0.6-0.9-1.41.20.9-0.51.7-1.4-0.1-1.41.3
Weight adjusted by age0.91.15.1-0.6-0.6-0.5-0.71.90.3-0.71.1-2.20.4-0.50.5
Bone surface3.76.618.02.52.52.44.2-3.1-2.11.7-1.93.3-0.72.3-2.3
Bone volume2.03.48.71.81.81.73.0-2.3-1.51.1-1.42.1-0.21.8-1.9
Breakpoint value in progressive ratio session1.11.22.0-1.0-1.0-1.1-1.00.61.2-1.21.1-0.11.3-1.31.4
Number of licking bursts0.70.81.90.80.80.91.3-1.1-0.50.2-1.40.70.70.9-1.1
Context. condit. distance diff. score0.20.30.9-0.5-0.5-0.5-1.00.40.3-0.10.4-0.2-0.5-0.70.8
Locomotion velocity, session 10.20.21.20.40.40.4-0.40.2-0.1-0.10.2-0.21.1-0.40.4
Locomotion distance, session 10.20.20.60.20.20.3-0.80.8-0.10.10.8-0.80.3-0.30.3
Locomotion velocity, session 20.70.91.41.21.21.20.4-1.1-1.01.1-0.61.0-0.70.6-0.5
Locomotion distance, session 20.81.12.41.61.61.50.3-0.8-1.21.4-0.30.9-0.80.5-0.5
Locomotion velocity, session 30.60.72.1-0.6-0.6-0.5-1.41.00.6-0.51.1-0.90.7-1.01.0
Locomotion distance, session 31.41.52.91.31.31.30.6-1.2-1.31.6-0.91.3-1.70.9-0.7
Stereotopy head waving bouts, day 31.21.42.5-1.6-1.6-1.5-1.40.81.3-1.31.0-0.60.7-1.00.9
Stereotopy head waving duration, day 30.00.00.2-0.3-0.3-0.1-0.4-0.20.1-0.0-0.30.2-0.0-0.00.0
Locomotion velocity, session 72.93.24.71.91.92.01.1-2.1-1.92.1-1.32.2-1.81.4-1.3
Locomotion distance, session 74.86.18.92.82.82.71.8-2.4-2.73.0-1.82.4-2.82.0-1.8
Stereotopy head waving bouts, day 71.11.22.4-1.6-1.6-1.5-0.70.41.3-1.21.00.10.6-1.21.2
Stereotopy head waving duration, day 70.60.71.8-1.3-1.3-1.2-0.30.01.0-0.90.20.20.4-0.70.8
Locomotion velocity, session 81.21.42.41.41.41.30.3-1.5-1.11.3-1.31.1-0.90.9-1.0
Locomotion distance, session 80.81.22.71.41.41.40.2-0.9-1.41.6-0.40.9-1.60.6-0.5
Degree of sensitization distance0.60.60.90.90.90.91.0-0.5-0.90.9-0.50.4-0.70.8-0.8
Degree of sensitization stereotypy0.80.91.8-1.3-1.3-1.3-0.40.41.1-1.00.8-0.10.5-1.01.1
Conditioned locomotion0.10.10.4-0.0-0.00.1-0.50.0-0.20.2-0.4-0.4-0.60.2-0.3
Cocaine response after cond. corrected0.91.01.9-1.4-1.4-1.3-0.70.91.2-1.20.6-1.00.3-0.80.8
Cocaine response after cond. not corrected0.40.40.7-0.8-0.8-0.7-0.50.40.8-0.80.5-0.50.4-0.70.7
Cocaine response before conditioning1.11.32.71.61.61.70.7-1.1-1.21.4-0.41.5-0.40.4-0.3
Saline control response0.10.20.30.20.20.40.50.6-0.20.20.5-0.40.2-0.40.5
Bone: connectivity density0.91.33.60.60.60.61.9-1.6-0.80.7-0.61.7-1.21.2-1.2
Bone: cortical apparent density4.15.47.4-2.4-2.4-2.4-2.72.62.3-2.22.3-2.61.5-2.22.1
Bone: cortical area0.71.14.21.11.10.90.3-0.9-1.21.7-0.40.9-2.00.3-0.1
Bone: cortical porosity0.70.73.30.80.80.81.0-1.2-0.60.6-0.61.80.30.3-0.3
Bone: cortical porosity0.91.03.31.11.11.01.1-1.3-0.80.8-0.91.80.20.5-0.5
Bone: cortical thickness7.211.721.8-3.4-3.4-3.5-4.73.53.0-2.04.2-2.40.4-4.14.3
Bone: cortical thickness1.51.83.2-1.5-1.5-1.5-1.81.01.2-0.81.7-0.4-0.3-1.51.7
Bone: cortical tissue density4.25.57.3-2.4-2.4-2.4-2.72.62.3-2.22.3-2.61.6-2.22.1
Condit. Reinf. active minus inactive responses0.40.42.00.40.40.3-0.10.5-0.80.7-0.2-0.8-1.40.4-0.4
Condit. Reinf. active-inactive response ratio0.60.74.00.40.40.30.2-0.1-1.00.9-0.7-0.1-2.00.8-0.8
Condit. Reinf. active responses0.20.20.8-0.2-0.2-0.3-0.60.8-0.10.10.5-0.9-0.8-0.10.1
Condit. Reinf. inactive responses0.40.41.4-0.4-0.4-0.4-0.50.60.6-0.51.2-0.30.9-0.80.7
Incentive salience index mean0.20.20.8-0.1-0.1-0.2-0.20.7-0.20.10.3-0.9-0.80.1-0.2
Condit. Reinf. lever presses0.20.20.9-0.5-0.5-0.5-0.10.70.3-0.40.9-0.5-0.0-0.20.1
Condit. Reinf. active minus inactive responses0.50.61.70.80.80.60.3-1.1-0.70.9-0.71.3-1.00.1-0.1
Condit. Reinf. active-inactive response ratio0.60.71.31.11.11.00.3-0.7-0.91.0-0.90.5-0.50.5-0.5
Condit. Reinf. active responses0.60.91.90.90.90.80.6-1.2-0.91.1-0.61.4-1.40.3-0.3
Condit. Reinf. inactive responses0.20.31.10.20.20.20.3-0.6-0.30.60.31.0-1.1-0.20.3
Condit. Reinf. lever presses2.63.55.22.32.32.11.6-1.6-2.12.2-1.61.5-1.91.6-1.5
Condit. Reinf. lever reinforcers received1.01.52.91.31.31.20.9-1.3-1.31.5-0.91.4-1.70.7-0.6
Conditioned reinforcement - actives0.20.20.50.30.30.30.4-0.7-0.30.5-0.50.6-0.50.3-0.2
Conditioned reinforcement - inactives2.83.26.61.81.81.81.3-1.5-2.02.2-1.71.2-2.61.7-1.6
Conditioned locomotion0.10.20.40.40.40.30.60.1-0.40.4-0.3-0.4-0.30.5-0.6
Patch foraging indifference point 0 sec0.30.51.70.70.70.80.3-0.5-0.81.00.00.8-1.30.10.2
Patch foraging indifference point AUC1.61.82.91.51.51.70.7-0.7-1.71.3-1.5-0.0-1.01.6-1.7
Delay disc. indifference point, 0s delay0.91.01.4-1.2-1.2-1.20.41.11.0-1.11.1-1.00.6-0.80.8
Delay disc. indifference point, 16s delay0.20.21.1-0.0-0.0-0.01.00.30.1-0.40.2-0.50.90.3-0.4
Delay disc. indifference point, 2s delay2.93.29.1-1.3-1.3-1.5-0.52.11.7-2.21.7-2.53.0-1.10.8
Delay disc. indifference point, 24s delay0.20.20.90.30.30.40.4-0.1-0.1-0.1-0.0-0.40.80.7-0.9
Delay disc. indifference point, 4s delay1.92.04.6-1.4-1.4-1.5-0.51.51.4-1.81.0-2.11.7-0.90.7
Delay disc. indifference point, 8s delay1.71.85.5-1.1-1.1-1.1-0.41.81.1-1.51.0-2.31.7-0.70.6
Indifference point function ln k0.71.02.1-1.1-1.1-1.2-0.80.51.0-0.61.3-0.0-0.2-1.31.5
Indifference point function log k0.71.02.1-1.1-1.1-1.2-0.80.51.0-0.61.3-0.0-0.2-1.31.5
Patch foraging total patch changes 0 sec0.30.51.80.70.70.80.3-0.5-0.81.10.00.9-1.30.10.2
Patch foraging total patch changes 12 sec2.02.64.32.02.01.91.1-1.2-2.02.1-1.11.2-1.71.3-1.1
Patch foraging total patch changes 18 sec0.30.31.20.60.60.60.2-0.4-0.70.7-0.20.4-1.10.5-0.3
Patch foraging total patch changes 24 sec3.03.65.62.22.22.01.3-1.5-2.32.4-1.71.2-2.41.6-1.3
Patch foraging total patch changes 6 sec0.81.22.21.31.31.40.6-0.0-1.51.5-0.4-0.3-1.31.1-1.0
Patch foraging time to switch 0 sec0.10.21.00.20.2-0.20.2-0.30.3-0.20.00.61.0-0.30.3
Patch foraging water rate 0 sec0.10.20.70.10.10.30.10.4-0.40.30.0-0.8-0.80.5-0.4
Patch foraging water rate 12 sec1.11.72.8-1.7-1.7-1.4-0.91.51.3-1.21.4-1.50.3-1.11.3
Patch foraging water rate 18 sec0.20.21.1-0.5-0.5-0.30.00.50.00.10.2-0.7-1.10.3-0.1
Patch foraging water rate 24 sec0.30.43.3-0.4-0.4-0.4-0.50.20.00.40.5-0.1-1.8-0.30.6
Patch foraging water rate 6 sec1.62.43.6-1.6-1.6-1.5-1.71.21.7-1.31.9-0.80.7-1.91.9
Seeking ratio, delayed vs. immediate footshock0.20.21.70.20.2-0.10.10.6-0.10.1-0.1-1.3-0.10.3-0.5
Distance traveled before self-admin0.80.91.5-1.1-1.1-1.2-0.70.51.1-1.00.4-0.50.5-1.11.2
Distance traveled after self-admin0.10.20.9-0.1-0.1-0.20.50.3-0.1-0.1-0.4-1.0-0.20.4-0.5
Extensor digitorum longus weight0.00.10.70.30.3-0.1-0.8-0.4-0.00.3-0.1-0.0-0.7-0.20.1
Bone: elastic displacement3.64.06.6-2.1-2.1-2.0-2.32.01.9-1.42.5-1.00.9-2.42.6
Bone: elastic work1.11.43.1-1.1-1.1-1.2-1.61.20.8-0.31.7-0.7-0.6-1.41.5
Bone: endosteal estimation20.243.956.67.17.17.17.5-6.8-6.86.1-7.25.1-4.66.8-6.8
Bone: endosteal perimeter15.732.647.56.16.16.16.9-5.7-5.74.9-6.14.1-3.16.2-6.2
Epididymis fat weight0.20.41.70.20.20.1-0.21.1-0.0-0.11.3-1.20.1-0.30.3
Delta time in closed arm before/after self-admin4.74.66.02.52.52.31.7-2.3-2.22.3-2.32.2-1.71.9-1.7
Delta time in open arm before/after self-admin5.55.37.7-2.0-2.0-2.0-2.32.62.1-2.32.8-2.42.2-2.42.3
Diff in mean of infusions in LGA sessions0.40.50.9-0.9-0.9-0.80.10.60.7-0.90.5-0.50.4-0.60.7
Delay discount exponential model param1.92.05.11.11.11.20.2-1.6-1.31.8-1.22.2-2.20.7-0.4
Extinction: sum of active levers before priming0.40.41.40.80.80.5-0.2-0.9-0.50.8-0.21.2-0.6-0.20.4
Active lever presses in extinction session 60.10.10.4-0.1-0.1-0.2-0.20.40.2-0.50.2-0.70.50.0-0.1
Bone: final force2.23.59.11.81.81.71.1-1.9-2.12.5-1.32.0-3.01.3-1.0
Bone: final moment1.42.37.51.41.41.20.6-1.6-1.62.1-0.71.8-2.70.7-0.5
Food consumed during 24 hour testing period0.30.31.80.50.50.51.3-0.6-0.30.2-0.40.50.10.4-0.5
Glucose0.30.50.90.90.90.90.3-0.6-0.80.9-0.90.2-0.50.6-0.6
Heart weight1.42.03.21.71.71.51.8-0.9-1.61.8-0.61.0-1.81.0-0.7
Delay discount hyperbolic model param1.92.05.21.11.11.20.2-1.7-1.31.8-1.22.3-2.30.7-0.5
Intermittent access intake day 1-15 change1.81.82.5-1.3-1.3-1.4-1.11.31.4-1.51.2-1.01.3-1.61.6
Intermittent access intake escalation1.91.82.5-1.2-1.2-1.4-0.91.61.3-1.51.3-1.21.2-1.61.6
Intermittent access intake escalation 23.43.45.0-1.7-1.7-1.8-1.12.01.9-2.11.7-1.82.2-1.81.8
Intermitt. access day 1 inactive lever presses1.21.25.11.01.01.2-0.3-0.8-1.21.6-0.31.0-2.30.4-0.3
Intermitt. access day 15 inactive lever presses0.50.51.01.01.00.90.1-0.2-0.90.8-0.4-0.4-0.60.8-0.8
Intermitt. access escalation Index1.21.11.31.11.11.00.6-1.1-1.11.1-1.20.6-0.91.1-1.2
Intermittent access day 1 total infusions1.11.22.31.31.31.40.8-0.3-1.41.5-0.9-0.4-1.11.1-1.1
Intermittent access day 15 total infusions0.30.41.90.50.50.40.60.6-0.60.4-0.4-1.4-0.40.5-0.5
Intermittent access terminal intake (last 3 days)0.30.30.50.60.60.60.70.1-0.60.6-0.6-0.7-0.40.7-0.7
Intermittent access total infusions1.31.52.21.41.41.41.1-0.2-1.51.5-1.1-0.6-1.31.3-1.2
Intermittent access day 1 locomotion0.91.01.91.41.41.10.30.0-1.21.3-0.5-0.9-0.90.8-0.9
Intermittent access day 15 total locomotion0.20.20.60.40.40.4-0.00.7-0.40.50.4-0.8-0.2-0.20.3
Intermittent access total locomotion0.70.81.81.41.41.10.50.2-1.21.2-0.3-0.8-0.60.6-0.6
Intermittent access standard deviation0.20.21.6-0.2-0.2-0.3-0.00.90.1-0.2-0.1-1.3-0.2-0.00.1
Left kidney weight0.10.31.2-0.5-0.5-0.80.60.50.4-0.70.2-1.1-0.20.1-0.1
Right kidney weight0.20.61.4-0.9-0.9-1.20.70.60.8-1.00.7-0.90.1-0.40.5
Cocaine induced anxiety0.50.50.80.90.90.70.4-0.9-0.70.8-0.50.7-0.80.6-0.8
Post-drug Anxiety1.71.93.01.71.71.60.5-1.7-1.41.5-1.21.4-1.01.0-1.1
Baseline Anxiety0.20.20.50.20.20.3-0.5-0.30.0-0.1-0.20.60.7-0.50.6
Tail length0.31.05.50.40.40.20.31.20.3-0.81.2-1.62.3-0.60.5
Length with tail0.31.33.9-0.5-0.5-0.70.70.91.1-1.12.0-0.81.9-1.11.1
Length without tail0.30.61.5-0.8-0.8-0.90.5-0.31.0-0.51.21.0-0.1-0.60.7
Times rat made contact with spout2.52.99.0-1.2-1.2-1.3-0.72.11.6-1.91.6-2.03.0-1.41.3
Lifetime Intake1.92.13.31.61.61.61.2-0.6-1.71.8-1.4-0.2-1.71.6-1.5
Liver weight, left0.20.31.4-0.2-0.2-0.31.2-0.70.10.00.10.9-0.70.3-0.2
Liver weight, right0.10.21.3-0.1-0.1-0.1-0.5-0.4-0.00.4-0.10.4-1.10.1-0.2
Locomotor activity1.22.02.71.41.41.61.0-1.3-1.51.6-1.60.9-1.61.4-1.3
Locomotor testing distance0.60.93.20.90.91.10.2-0.7-1.11.3-0.70.5-1.80.7-0.6
Locomotor testing rearing0.00.10.20.00.00.3-0.10.4-0.30.20.2-0.5-0.50.00.0
Locomotion in novel chamber0.20.20.90.20.20.00.5-0.60.0-0.1-0.40.30.20.7-1.0
Locomotion in novel chamber post-restriction0.50.63.10.50.50.61.2-0.9-0.40.60.31.8-0.30.1-0.0
Fecal boli incidents, locomotor time 10.30.30.80.70.70.60.9-0.4-0.50.6-0.60.4-0.00.2-0.0
Change in fecal boli incidents, locomotor task0.70.61.0-1.0-1.0-0.7-0.70.90.7-0.80.9-0.60.0-0.90.9
Time >=10cm from walls, locomotor time 11.11.22.00.70.70.71.3-1.3-1.01.0-1.40.9-1.41.1-1.0
Bouts of movement, locomotor time 10.10.10.40.30.30.6-0.5-0.2-0.30.50.1-0.0-0.10.3-0.4
Total resting periods, locomotor time 10.10.10.50.10.10.4-0.7-0.1-0.10.20.2-0.00.30.1-0.2
Rest time, locomotor task time 10.70.71.3-1.1-1.1-0.8-0.90.50.9-0.70.9-0.00.5-1.01.1
Distance moved, locomotor task time 10.40.51.9-0.3-0.3-0.5-0.71.00.6-0.70.7-1.40.7-0.40.3
Vertical activity count, locomotor time 11.61.73.01.71.71.61.2-0.3-1.61.5-0.80.0-1.11.2-1.1
Time >=10cm from walls, locomotor time 20.10.10.4-0.1-0.1-0.0-0.50.40.1-0.10.6-0.50.1-0.50.5
Bouts of movement, locomotor time 21.21.32.7-1.0-1.0-1.0-1.61.11.0-1.11.1-1.51.2-0.70.4
Total resting periods, locomotor time 20.80.92.5-0.7-0.7-0.7-1.51.00.7-0.90.8-1.61.0-0.30.0
Rest time, locomotor task time 20.10.10.2-0.3-0.3-0.2-0.4-0.30.10.1-0.00.5-0.30.1-0.1
Distance moved, locomotor task time 20.10.20.9-0.1-0.1-0.20.10.70.3-0.30.4-0.90.3-0.40.3
Vertical activity count, locomotor time 20.10.20.60.20.2-0.00.20.7-0.10.00.4-0.6-0.1-0.50.6
Light reinforcement 10.40.83.20.60.60.50.3-0.3-0.91.0-0.6-0.0-1.81.1-1.1
Light reinforcement 22.12.94.61.71.71.81.4-1.5-1.81.8-1.60.9-1.52.0-2.1
Bone: marrow area19.943.255.47.07.07.07.4-6.8-6.86.0-7.15.1-4.56.7-6.7
Bone: maximum diameter10.319.023.04.64.64.54.8-4.5-4.54.3-4.73.5-3.64.2-4.1
Bone: maximum force3.25.610.22.52.52.41.7-2.5-2.62.9-1.82.3-3.21.8-1.6
Bone: maximum moment2.13.58.12.02.01.81.1-2.0-2.12.4-1.22.0-2.81.2-1.0
Mean time between licks in bursts0.70.91.91.11.11.10.9-1.4-0.80.9-0.81.1-0.50.8-0.8
Mean num. licks in bursts2.12.64.9-1.3-1.3-1.4-1.72.21.3-1.12.2-1.80.7-1.71.8
Cd content in liver0.20.20.70.10.10.3-0.3-0.2-0.20.50.60.7-0.8-0.50.6
Co content in liver0.91.02.1-1.0-1.0-1.2-0.91.31.1-1.10.9-1.50.8-0.30.1
Cu content in liver0.10.10.80.10.1-0.00.9-0.3-0.10.0-0.20.2-0.20.4-0.3
Fe content in liver0.50.62.00.70.70.50.9-0.8-0.50.90.31.4-1.00.10.1
K content in liver0.30.31.2-0.4-0.4-0.5-1.1-0.00.6-0.6-0.3-0.40.9-0.30.1
Mg content in liver0.00.00.30.10.10.1-0.1-0.10.1-0.2-0.3-0.20.50.0-0.2
Mn content in liver0.60.62.40.40.40.41.6-1.0-0.50.3-1.00.9-0.00.8-0.9
Na content in liver0.30.31.10.50.50.30.2-1.1-0.20.1-1.00.70.40.5-0.6
Rb content in liver0.50.61.60.50.50.50.3-0.3-0.80.5-1.3-0.6-1.11.1-1.2
Se content in liver0.50.63.2-0.3-0.3-0.3-0.41.00.4-0.9-0.0-1.81.4-0.30.2
Sr content in liver1.51.32.11.31.31.31.4-0.8-1.21.0-1.00.5-0.51.5-1.5
Zn content in liver0.10.10.3-0.4-0.4-0.5-0.1-0.40.3-0.3-0.20.1-0.40.3-0.4
Bone: minimum diameter5.911.015.23.53.53.53.9-3.4-3.53.1-3.42.6-2.53.4-3.4
Time in familiar zone, hab. session 10.10.10.6-0.2-0.2-0.20.20.10.2-0.10.80.1-0.3-0.50.6
Time in novel zone, hab. session 10.20.21.0-0.2-0.2-0.1-0.20.6-0.1-0.2-0.4-1.00.00.3-0.4
Total zone transitions, hab. session 10.40.51.4-0.2-0.2-0.3-0.31.10.5-0.61.2-1.10.9-0.60.5
Total locomotion distance, hab. session 10.10.20.40.20.20.20.40.6-0.40.20.6-0.6-0.50.5-0.6
Locomotion velocity, hab. session 10.10.20.50.40.40.50.40.2-0.50.40.4-0.2-0.30.6-0.7
Time in familiar zone, hab. session 20.70.71.1-0.9-0.9-0.9-1.00.81.0-0.90.7-0.90.8-0.60.5
Time in novel zone, hab. session 21.61.63.71.11.11.21.0-1.4-1.41.6-1.31.4-1.90.8-0.6
Total zone transitions, hab. session 20.30.30.70.80.80.80.1-0.4-0.70.7-0.20.3-0.30.6-0.6
Total locomotion distance, hab. session 20.20.20.70.40.40.4-0.2-0.2-0.50.4-0.10.3-0.60.7-0.8
Locomotion velocity, hab. session 20.20.20.90.40.40.4-0.0-0.2-0.40.3-0.20.2-0.50.8-0.9
Novel to familiar place preference ratio0.20.20.6-0.4-0.4-0.4-0.20.50.4-0.50.4-0.80.3-0.20.1
Novelty place preference0.00.00.1-0.1-0.1-0.20.10.10.1-0.20.1-0.4-0.00.1-0.2
Time in novel zone, NPP test0.00.00.10.00.0-0.10.10.1-0.00.00.1-0.3-0.20.1-0.2
Total zone transitions, NPP test0.20.40.90.90.90.9-0.3-0.0-0.50.70.50.50.3-0.40.5
Total locomotion distance, NPP test0.30.40.80.80.80.8-0.60.3-0.70.90.80.4-0.3-0.30.4
Locomotion velocity, NPP test0.20.31.10.30.30.3-0.90.7-0.20.31.1-0.10.2-0.50.6
Intraocular pressure1.41.94.91.51.51.41.5-1.8-1.31.3-0.72.2-0.91.0-0.8
Delta distance traveled before/after self-admin1.31.42.91.01.01.01.4-0.2-1.41.0-0.9-0.7-1.41.6-1.7
Delta ambulatory time before/after self-admin1.71.84.81.01.01.11.8-0.6-1.41.0-1.3-0.2-1.22.1-2.2
Parametrial fat weight0.40.81.61.21.21.30.5-0.5-1.11.0-0.70.1-0.70.7-0.6
Pavlov. Cond. lever latency1.82.33.31.51.51.51.5-1.8-1.51.5-1.71.6-1.61.2-1.0
Pavlov. Cond. magazine entry latency2.93.75.8-2.3-2.3-2.4-1.42.22.0-2.11.7-2.21.3-1.51.4
Pavlov. Cond. change in total contacts1.21.32.0-1.1-1.1-1.3-1.41.41.1-0.91.4-1.40.4-1.00.9
Pavlov. Cond. index score2.43.04.6-1.9-1.9-2.0-1.72.11.8-1.81.6-2.11.3-1.31.2
Pavlov. Cond. latency score3.03.85.1-2.1-2.1-2.2-1.82.32.0-2.11.9-2.21.7-1.61.5
Pavlov. Cond. lever contacts1.82.23.0-1.5-1.5-1.6-1.61.71.5-1.41.7-1.61.2-1.10.9
Pavlov. Cond. magazine entry number3.64.56.62.42.42.61.6-2.3-2.22.2-2.02.1-1.31.9-2.0
Pavlov. Cond. intertrial magazine entries0.30.30.90.90.90.80.3-0.2-0.70.7-0.0-0.0-0.40.3-0.3
Pavlov. Cond. lever-magazine prob. diff.2.02.54.8-1.7-1.7-1.8-1.52.01.5-1.61.4-2.21.1-1.00.9
Pavlov. Cond. response bias1.92.33.4-1.7-1.7-1.8-1.41.81.5-1.41.7-1.70.7-1.21.2
Pavlov. Cond. lever latency1.52.03.0-1.6-1.6-1.5-0.81.31.6-1.71.5-1.41.6-1.21.1
Pavlov. Cond. magazine entry latency3.94.56.62.32.32.31.3-2.4-2.22.5-2.22.6-2.01.5-1.2
Pavlov. Cond. change in total contacts4.15.67.72.52.52.51.1-2.7-2.42.8-2.62.6-2.71.8-1.6
Pavlov. Cond. index score3.74.76.42.42.42.31.5-2.3-2.32.5-2.22.5-2.11.7-1.5
Pavlov. Cond. latency score4.15.16.92.52.52.41.6-2.4-2.32.6-2.22.6-2.21.7-1.5
Pavlov. Cond. lever contacts1.21.72.31.51.51.40.9-1.1-1.41.5-1.31.3-1.31.1-1.0
Pavlov. Cond. magazine entry number4.35.28.0-2.5-2.5-2.4-1.22.52.4-2.82.3-2.72.5-1.51.2
Pavlov. Cond. intertrial magazine entries0.30.42.90.00.0-0.11.70.1-0.3-0.2-0.2-0.5-0.30.9-0.9
Pavlov. Cond. lever-magazine prob. diff.3.54.56.12.32.32.31.4-2.3-2.22.5-2.22.5-2.01.6-1.4
Pavlov. Cond. response bias1.92.63.81.81.81.71.0-1.6-1.72.0-1.71.9-1.71.1-0.9
Time in closed arm before self-admin0.10.20.40.00.00.30.5-0.0-0.40.1-0.7-0.4-0.30.5-0.5
Time in closed arm after self-admin3.73.87.71.61.61.72.3-1.9-2.01.8-2.81.0-2.32.1-1.9
Time in open arm before self-admin0.20.20.7-0.2-0.2-0.3-0.50.20.6-0.30.50.20.8-0.50.4
Time in open arm after self-admin0.70.72.50.10.10.0-1.40.90.5-0.41.3-0.81.6-0.80.6
Bone: periosteal estimation11.123.027.05.25.25.15.1-4.9-5.14.9-5.03.8-4.14.6-4.4
Bone: periosteal perimeter5.89.712.93.43.43.33.6-3.2-3.23.0-3.22.3-2.13.3-3.3
Bone: post-yield work5.06.89.22.82.82.93.0-2.1-2.92.5-2.61.0-2.32.9-2.9
Progressive ratio test 1 active lever presses0.30.31.00.60.60.40.20.3-0.70.7-0.1-1.0-0.80.4-0.4
Progressive ratio test 1 breakpoint0.30.31.30.50.50.30.10.4-0.60.60.0-1.2-0.80.2-0.2
Progressive ratio test 1 inactive lever presses2.12.37.21.61.61.40.9-1.0-1.82.0-1.40.3-2.71.3-1.1
Progressive ratio test 2 active lever presses0.60.61.11.01.00.80.9-0.2-0.90.8-0.6-0.3-0.51.0-1.0
Progressive ratio test 2 breakpoint0.60.71.21.11.10.90.8-0.3-1.00.9-0.6-0.1-0.40.9-0.9
Progressive ratio test 2 inactive lever presses1.31.52.41.41.41.40.9-0.8-1.41.6-1.10.3-1.41.2-1.2
Incentive Sensitization - Responses0.30.30.60.50.50.40.8-0.5-0.40.3-0.60.3-0.00.8-0.8
Incentive Sensitization - Breakpoint0.20.20.60.30.30.20.8-0.4-0.20.0-0.50.20.10.6-0.7
Sum of active levers in priming session hrs 5-60.50.50.9-0.7-0.7-0.7-0.70.90.7-0.70.9-0.40.3-0.80.9
Progressive ratio1.41.65.60.90.91.01.2-2.0-0.70.8-1.42.4-0.11.1-1.1
Food seeking constrained by brief footshock0.30.41.0-1.0-1.0-0.7-0.5-0.40.8-0.7-0.10.50.6-0.20.1
Seeking ratio, punishment vs. effort1.21.52.7-1.2-1.2-1.3-1.41.41.1-1.21.1-1.60.6-1.11.1
Retroperitoneal fat weight0.10.30.50.60.60.50.60.6-0.70.60.4-0.7-0.70.5-0.5
Reaction time number correct0.10.20.90.10.10.10.5-0.4-0.10.30.40.9-0.6-0.40.6
Reaction time mean minus median0.20.32.4-0.5-0.5-0.21.60.60.0-0.30.4-0.50.20.2-0.1
Reaction time mean minus median AUC0.50.74.5-0.0-0.00.32.1-0.4-0.60.5-0.50.5-1.10.9-0.7
Reaction time num false alarms0.10.20.70.10.10.20.8-0.6-0.20.2-0.50.5-0.50.5-0.4
Reaction time num false alarms AUC0.10.10.60.00.00.10.8-0.6-0.00.0-0.40.7-0.10.2-0.2
Reaction time trials correct on left0.10.20.90.10.10.10.5-0.4-0.10.30.40.9-0.6-0.40.6
Reaction time trials on left0.20.21.00.10.10.10.6-0.5-0.20.40.41.0-0.6-0.30.5
Reaction time mean0.20.32.10.30.30.71.50.3-0.70.4-0.3-0.3-0.40.5-0.3
Reaction time mean AUC0.50.72.10.60.61.01.4-0.2-1.00.9-0.70.2-0.90.8-0.6
Median of all reaction times0.40.51.60.60.61.01.30.1-0.90.8-0.7-0.1-0.70.7-0.5
Reaction time omissions0.91.37.30.70.70.72.7-0.8-0.91.0-0.81.0-1.20.9-0.6
Reaction time false alarm rate0.10.10.2-0.2-0.2-0.10.4-0.30.3-0.3-0.40.10.40.2-0.3
Reaction time premature initiation rate6.48.516.9-2.7-2.7-2.8-3.03.42.8-3.22.7-4.12.9-2.21.8
Reaction time premature initiations3.34.78.4-2.0-2.0-2.1-2.12.52.1-2.32.2-2.91.8-1.81.6
Std. dev. reaction times0.10.21.9-0.3-0.30.11.40.3-0.1-0.20.3-0.10.20.00.2
Reaction time trials completed0.20.21.00.10.10.10.6-0.5-0.20.40.41.0-0.6-0.30.5
Reaction time trials AUC0.20.31.10.30.30.20.6-0.6-0.30.50.21.1-0.7-0.20.4
Run reversals in cocaine runway, females1.21.23.1-1.0-1.0-1.0-1.81.11.1-0.91.0-1.01.1-1.01.0
Run reversals in cocaine runway, males0.10.10.80.00.0-0.1-0.90.20.1-0.10.0-0.6-0.00.3-0.5
Latency to leave start box in cocaine runway0.20.20.7-0.7-0.7-0.7-0.10.50.3-0.40.2-0.6-0.80.0-0.0
Latency to leave start box in cocaine runway, F1.61.82.8-1.5-1.5-1.6-0.51.71.3-1.31.4-1.70.1-1.21.2
Latency to leave start box in cocaine runway, M1.11.12.40.50.50.60.7-1.0-1.00.8-1.30.7-1.51.5-1.5
Std. dev. time between licks in bursts1.61.93.21.61.61.70.1-1.6-1.41.8-1.01.5-1.41.0-1.0
Total sessions with >9 infusions0.20.30.7-0.1-0.1-0.10.50.4-0.10.1-0.3-0.8-0.70.8-0.8
Short access day 1 total inactive lever presses1.92.14.71.61.61.60.7-1.1-1.72.0-1.30.7-2.21.2-1.1
Short access day 10 total inactive lever presses1.71.93.81.51.51.60.3-1.3-1.51.8-1.10.8-2.01.2-1.2
Short access day 1 total infusions0.70.82.30.50.50.70.4-0.8-0.81.1-1.10.6-1.50.9-0.8
Short access day 10 total infusions1.01.22.40.80.80.81.20.0-1.21.2-1.2-0.7-1.51.3-1.2
Short access total infusions1.92.13.71.41.41.51.1-0.8-1.71.8-1.60.1-1.91.6-1.5
Short access day 1 locomotion0.20.31.4-0.0-0.0-0.20.10.9-0.20.2-0.0-1.2-0.70.4-0.4
Short access day 10 total locomotion0.40.51.21.11.10.80.5-0.1-0.80.7-0.8-0.4-0.40.5-0.6
Short access total locomotion0.20.32.00.20.2-0.20.10.9-0.10.2-0.1-1.4-0.40.1-0.0
One hour access (0.3 mA shock)1.01.11.61.11.10.91.2-0.9-1.11.1-1.00.6-1.21.2-1.2
Compulsive drug intake0.50.51.20.70.70.80.0-0.9-0.70.9-0.21.1-0.90.3-0.2
One hour access (shock baseline)0.30.41.30.50.50.41.1-0.2-0.40.3-0.8-0.2-0.00.8-0.9
Social response proportion0.70.71.6-1.1-1.1-0.90.41.20.7-0.90.7-1.30.3-0.40.4
Social responses0.81.01.9-1.1-1.1-1.20.31.40.8-0.71.2-1.0-0.5-0.91.1
Social time0.30.41.80.00.00.11.40.8-0.50.20.0-1.2-0.80.4-0.3
Soleus weight0.72.05.01.31.31.30.8-1.3-1.31.2-2.20.5-1.41.8-1.8
Bone: stiffness4.67.210.22.82.82.82.3-2.8-2.93.0-2.72.0-3.22.5-2.3
Tibialis anterior weight0.00.10.4-0.2-0.2-0.2-0.0-0.50.1-0.1-0.60.0-0.60.4-0.5
Time to tail flick, vehicle, before self-admin0.40.40.90.80.80.9-0.0-0.6-0.70.7-0.10.7-0.40.5-0.6
Time to tail flick, vehicle, after self-admin0.50.51.1-0.8-0.8-0.9-0.30.70.8-1.10.3-0.70.9-0.50.5
Time to tail flick, test, before self-admin0.50.53.8-0.3-0.3-0.3-0.70.10.7-0.80.3-0.21.9-0.30.0
Time to tail flick, test, after self-admin0.60.71.8-0.4-0.4-0.8-0.60.41.0-0.70.7-0.11.3-1.21.1
Delta time to tail flick, vehicle, before/after SA1.71.72.3-1.4-1.4-1.5-0.71.51.3-1.51.0-1.41.2-1.21.3
Delta time to tail flick, test, before/after SA0.30.31.50.20.2-0.1-0.0-0.50.00.40.01.2-0.6-0.70.8
Tibia length0.41.12.1-1.5-1.5-1.4-1.00.61.2-0.90.6-0.40.4-1.21.3
Ambulatory time before self-admin1.71.83.1-1.4-1.4-1.5-1.31.11.4-1.31.0-1.00.8-1.61.8
Ambulatory time after self-admin0.10.10.7-0.3-0.3-0.40.00.40.2-0.3-0.0-0.90.20.0-0.0
Bone: tissue strength0.40.41.5-0.3-0.3-0.4-1.10.5-0.00.30.6-0.3-1.2-0.50.5
Total heroin consumption0.20.20.80.10.1-0.1-0.3-0.70.2-0.1-0.50.90.4-0.30.5
Bone: trabecular number0.20.31.5-0.5-0.5-0.40.7-0.90.4-0.40.31.20.1-0.0-0.0
Bone: trabecular spacing0.10.10.7-0.0-0.0-0.1-0.60.6-0.00.1-0.2-0.9-0.2-0.30.4
Bone: trabecular thickness0.00.00.20.30.30.2-0.1-0.3-0.00.00.00.00.40.0-0.2
Bone: trabecular tissue density0.20.31.00.00.00.1-0.20.90.2-0.40.4-1.01.0-0.30.2
Water consumed over 24 hours0.10.21.00.00.00.00.50.40.1-0.40.4-0.51.00.0-0.1
Number of responses in last shaping day1.01.02.20.90.90.71.10.1-1.10.8-0.9-0.9-1.11.4-1.5