Hub : Genes

LOC102546598

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression LOC102546598 0.11 0.07 3.5e-06 0.03 0.05 0.04 0.03 4.1e-04 7.2e-06 4.7e-05 2.0e-04
2 Liver alternative polyA XR_005490430.1 0.02 0.02 3.8e-03 0.01 0 -0 0 7.5e-03 1.5e-01 6.0e-01 2.4e-01
3 Liver alternative polyA XR_005490432.1 0.02 0.02 4.5e-03 0.01 0 -0 0 1.0e-02 2.0e-01 6.4e-01 2.8e-01
4 IL gene expression LOC102546598 0.32 0.13 2.8e-04 0.2 0.18 0.16 0.18 1.5e-05 4.8e-05 9.5e-05 3.6e-05
5 NAcc isoform ratio XR_005490429.1 0.02 0.01 6.0e-03 0.01 0.02 0.02 0.02 7.0e-03 3.3e-03 3.9e-03 4.4e-03
6 pVTA intron excision ratio chr10_80255817_80259063 0.06 0.04 8.2e-03 0.01 0.04 0.04 0.03 7.3e-02 7.4e-03 9.1e-03 2.7e-02
7 PL isoform ratio XR_005490429.1 0.09 0.08 9.6e-03 0.01 0.01 0 0.01 3.7e-02 7.3e-03 1.8e-01 3.7e-02
8 Liver intron excision ratio chr10_80281653_80307929 0.02 0.02 2.1e-03 0.01 0.02 0.01 0.01 2.2e-02 5.5e-03 1.8e-02 1.5e-02
9 NAcc intron excision ratio chr10_80281653_80307929 0.05 0.03 9.5e-03 0 0.01 0.02 0.01 9.7e-02 1.2e-02 3.5e-03 5.3e-02
10 Adipose gene expression LOC102546598 0.1 0.06 4.9e-08 0.06 0.06 0.06 0.06 1.4e-07 4.8e-07 4.8e-07 1.8e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.30.52.90.8-0.60.6-0.50.6-0.6-1.7-0.30.00.3
Area under the delay curve0.00.00.10.3-0.30.3-0.30.10.10.00.1-0.10.0
BMI with tail3.110.245.64.6-1.61.6-2.32.8-0.9-3.80.36.8-1.1
BMI without tail1.02.17.50.40.8-0.80.4-0.61.4-2.21.92.71.1
Body weight0.51.95.52.3-1.31.3-1.41.3-0.2-0.30.32.3-1.0
Weight adjusted by age0.10.10.3-0.30.2-0.2-0.1-0.10.3-0.10.40.50.2
Bone surface0.20.30.60.8-0.80.8-0.70.5-0.3-0.5-0.10.3-0.2
Bone volume0.71.12.11.4-1.41.4-1.21.2-1.1-0.2-0.90.0-0.7
Breakpoint value in progressive ratio session1.82.03.7-1.01.1-1.11.3-1.61.7-1.61.9-0.61.6
Number of licking bursts1.41.62.8-1.71.7-1.71.6-1.41.0-0.10.7-0.91.1
Context. condit. distance diff. score0.30.40.80.6-0.40.4-0.50.7-0.7-0.0-0.60.9-0.6
Locomotion velocity, session 10.50.51.1-0.50.7-0.70.6-0.60.90.40.81.10.1
Locomotion distance, session 12.12.74.9-2.21.8-1.81.7-1.92.01.51.70.20.7
Locomotion velocity, session 20.30.43.1-0.1-0.40.4-0.40.00.11.70.1-0.3-0.6
Locomotion distance, session 23.44.77.8-2.82.4-2.42.5-2.52.61.12.3-0.11.3
Locomotion velocity, session 31.61.82.61.6-1.51.5-1.61.4-0.91.3-0.80.8-1.6
Locomotion distance, session 30.30.40.6-0.70.5-0.50.7-0.70.80.30.7-0.30.4
Stereotopy head waving bouts, day 32.83.44.81.9-2.02.0-1.72.2-2.20.6-2.10.8-2.0
Stereotopy head waving duration, day 32.73.34.81.7-1.91.9-1.82.1-2.20.9-2.20.4-1.9
Locomotion velocity, session 70.80.96.6-0.2-0.10.1-0.1-0.00.32.60.10.6-1.2
Locomotion distance, session 71.72.24.5-2.11.6-1.61.6-1.61.11.70.5-1.70.6
Stereotopy head waving bouts, day 70.30.30.90.6-0.80.8-0.50.5-0.2-0.20.11.0-0.4
Stereotopy head waving duration, day 70.40.51.10.7-1.11.1-0.70.7-0.50.0-0.20.6-0.5
Locomotion velocity, session 80.91.16.31.0-0.60.6-0.50.70.00.80.22.5-1.2
Locomotion distance, session 80.71.01.6-1.11.1-1.11.0-1.11.30.11.30.90.6
Degree of sensitization distance0.30.31.4-0.30.1-0.1-0.10.1-0.41.2-0.7-0.7-0.4
Degree of sensitization stereotypy0.60.71.4-0.70.6-0.60.8-0.91.0-1.11.20.31.0
Conditioned locomotion0.70.81.40.9-1.01.0-0.91.0-1.2-0.4-1.1-0.6-0.5
Cocaine response after cond. corrected1.01.23.11.6-0.80.8-0.91.2-1.0-1.8-0.80.9-0.3
Cocaine response after cond. not corrected0.70.83.91.1-0.40.4-0.70.8-0.9-2.0-0.70.00.2
Cocaine response before conditioning1.01.23.5-1.51.0-1.00.9-1.10.6-0.20.4-1.91.2
Saline control response0.91.21.6-1.31.1-1.11.2-1.11.0-1.01.10.01.2
Bone: connectivity density0.60.96.70.30.1-0.10.0-0.20.3-2.60.7-0.11.3
Bone: cortical apparent density1.01.46.3-1.50.8-0.81.0-0.70.02.5-0.7-1.4-0.5
Bone: cortical area0.50.71.20.8-1.01.0-1.10.8-0.40.9-0.30.9-1.0
Bone: cortical porosity0.20.20.70.4-0.40.4-0.30.4-0.10.40.00.8-0.5
Bone: cortical porosity0.10.10.10.1-0.30.3-0.20.3-0.20.3-0.10.4-0.4
Bone: cortical thickness1.22.05.30.7-1.21.2-1.21.3-1.22.3-1.31.1-2.0
Bone: cortical thickness0.10.10.2-0.30.4-0.40.1-0.1-0.00.4-0.30.4-0.2
Bone: cortical tissue density1.11.55.9-1.60.9-0.91.1-0.80.12.4-0.6-1.5-0.4
Condit. Reinf. active minus inactive responses0.91.11.9-0.81.2-1.21.0-1.21.4-0.41.30.21.0
Condit. Reinf. active-inactive response ratio0.10.10.5-0.20.4-0.40.3-0.20.2-0.30.20.70.1
Condit. Reinf. active responses1.11.32.4-0.81.3-1.31.1-1.31.6-0.51.50.01.2
Condit. Reinf. inactive responses1.31.62.3-0.91.3-1.31.2-1.51.5-0.91.5-0.81.5
Incentive salience index mean2.22.64.2-1.51.9-1.91.6-1.82.0-0.52.00.31.5
Condit. Reinf. lever presses3.04.05.5-2.12.3-2.32.3-2.32.4-0.52.20.11.8
Condit. Reinf. active minus inactive responses1.31.63.0-0.91.2-1.21.1-1.31.2-1.71.3-0.61.7
Condit. Reinf. active-inactive response ratio4.75.09.4-1.62.4-2.42.0-2.22.0-3.12.1-0.52.9
Condit. Reinf. active responses0.30.40.7-0.50.6-0.60.5-0.70.8-0.50.80.10.7
Condit. Reinf. inactive responses1.01.24.20.5-1.01.0-0.80.9-0.72.0-0.70.9-1.5
Condit. Reinf. lever presses0.30.51.70.3-0.40.4-0.30.00.61.30.71.1-0.6
Condit. Reinf. lever reinforcers received0.30.40.9-0.40.5-0.50.5-0.70.8-0.60.90.00.8
Conditioned reinforcement - actives0.90.91.6-0.81.0-1.00.8-0.91.20.11.31.00.6
Conditioned reinforcement - inactives0.20.20.5-0.70.5-0.50.5-0.3-0.00.5-0.3-0.7-0.0
Conditioned locomotion0.50.60.8-0.80.9-0.90.6-0.70.7-0.60.80.70.9
Patch foraging indifference point 0 sec0.61.03.51.9-1.11.1-1.01.1-0.9-1.0-0.6-0.0-0.6
Patch foraging indifference point AUC0.91.03.80.1-0.50.5-0.10.30.31.90.21.9-1.3
Delay disc. indifference point, 0s delay0.10.10.90.1-0.10.1-0.20.10.10.9-0.00.3-0.3
Delay disc. indifference point, 16s delay0.70.71.81.3-1.01.0-1.11.0-0.7-0.4-0.40.5-0.6
Delay disc. indifference point, 2s delay0.40.42.3-0.2-0.70.7-0.50.1-0.50.2-0.6-1.5-0.1
Delay disc. indifference point, 24s delay0.70.71.8-0.60.7-0.70.6-0.81.20.11.30.80.6
Delay disc. indifference point, 4s delay0.20.21.00.0-0.40.4-0.50.0-0.10.9-0.2-1.0-0.2
Delay disc. indifference point, 8s delay0.00.00.3-0.0-0.00.0-0.0-0.1-0.0-0.2-0.1-0.60.3
Indifference point function ln k0.20.31.2-0.10.4-0.40.3-0.3-0.1-1.0-0.2-1.10.7
Indifference point function log k0.20.31.2-0.10.4-0.40.3-0.3-0.1-1.0-0.2-1.10.7
Patch foraging total patch changes 0 sec0.81.44.12.0-1.31.3-1.21.3-1.0-0.8-0.8-0.1-0.7
Patch foraging total patch changes 12 sec0.00.00.00.2-0.10.1-0.10.00.20.20.2-0.0-0.2
Patch foraging total patch changes 18 sec1.31.73.31.8-1.51.5-1.31.4-0.90.3-0.61.4-1.5
Patch foraging total patch changes 24 sec0.50.61.51.2-1.11.1-0.70.8-0.6-0.9-0.30.2-0.3
Patch foraging total patch changes 6 sec0.81.12.81.7-1.21.2-0.81.0-0.20.20.01.6-1.1
Patch foraging time to switch 0 sec0.10.20.6-0.80.4-0.40.6-0.50.3-0.10.2-0.30.3
Patch foraging water rate 0 sec0.91.43.01.7-1.11.1-1.31.5-1.10.1-0.91.4-1.1
Patch foraging water rate 12 sec0.50.82.71.6-1.01.0-1.20.9-0.4-0.2-0.21.0-0.6
Patch foraging water rate 18 sec0.30.42.10.30.2-0.2-0.2-0.0-0.2-1.0-0.2-1.50.7
Patch foraging water rate 24 sec0.40.61.51.2-0.60.6-1.00.9-0.7-0.4-0.50.4-0.6
Patch foraging water rate 6 sec0.81.22.7-0.20.9-0.90.8-0.71.1-1.61.41.51.0
Seeking ratio, delayed vs. immediate footshock0.70.91.71.3-1.01.0-1.31.1-0.9-0.0-0.80.1-0.8
Distance traveled before self-admin4.54.87.0-2.42.3-2.32.4-2.52.6-1.12.60.22.2
Distance traveled after self-admin1.82.06.9-0.71.5-1.51.2-1.11.1-2.61.40.21.7
Extensor digitorum longus weight0.83.27.22.7-2.12.1-1.91.8-0.70.3-0.32.3-1.7
Bone: elastic displacement0.10.10.6-0.10.2-0.20.4-0.20.3-0.00.30.8-0.0
Bone: elastic work0.10.10.6-0.1-0.10.10.2-0.10.30.30.30.8-0.3
Bone: endosteal estimation0.10.20.80.00.0-0.0-0.1-0.30.6-0.90.80.00.7
Bone: endosteal perimeter0.10.31.30.6-0.20.2-0.3-0.10.5-1.10.8-0.10.6
Epididymis fat weight0.10.31.80.3-0.00.0-0.1-0.20.4-1.30.6-0.50.7
Delta time in closed arm before/after self-admin0.60.61.10.8-0.90.9-1.10.7-0.60.8-0.5-0.0-0.9
Delta time in open arm before/after self-admin0.10.10.30.1-0.00.00.10.2-0.30.5-0.40.1-0.2
Diff in mean of infusions in LGA sessions2.42.65.1-1.11.7-1.71.5-1.62.2-0.22.31.61.3
Delay discount exponential model param0.00.00.1-0.20.2-0.20.20.0-0.20.1-0.20.1-0.2
Extinction: sum of active levers before priming0.20.20.7-0.0-0.30.3-0.1-0.30.60.90.7-0.2-0.2
Active lever presses in extinction session 60.10.10.40.20.1-0.10.20.00.2-0.70.30.60.0
Bone: final force0.00.00.2-0.20.1-0.10.10.1-0.30.1-0.4-0.1-0.1
Bone: final moment0.00.00.2-0.1-0.00.00.00.2-0.30.2-0.40.1-0.3
Food consumed during 24 hour testing period1.01.22.5-1.01.0-1.01.0-1.31.6-0.21.6-0.01.1
Glucose2.33.58.21.0-1.71.7-1.81.9-2.70.9-2.9-1.8-1.4
Heart weight0.40.61.41.2-0.90.9-1.10.8-0.6-0.5-0.5-0.3-0.3
Delay discount hyperbolic model param0.00.00.1-0.10.3-0.30.3-0.0-0.0-0.1-0.00.4-0.1
Intermittent access intake day 1-15 change0.60.62.61.1-0.10.10.10.00.7-0.91.01.6-0.1
Intermittent access intake escalation0.50.51.71.0-0.00.00.2-0.00.8-0.70.91.3-0.0
Intermittent access intake escalation 21.11.13.30.80.5-0.50.7-0.41.2-1.81.41.40.8
Intermitt. access day 1 inactive lever presses0.60.61.2-0.71.0-1.01.1-0.60.3-1.00.2-0.50.8
Intermitt. access day 15 inactive lever presses1.61.72.41.5-1.51.5-1.31.5-1.30.8-1.20.9-1.5
Intermitt. access escalation Index0.50.40.7-0.50.8-0.80.7-0.60.5-0.70.5-0.20.8
Intermittent access day 1 total infusions0.40.52.4-1.00.1-0.10.0-0.3-0.30.9-0.6-1.5-0.0
Intermittent access day 15 total infusions0.20.20.8-0.30.3-0.30.5-0.60.90.30.80.00.1
Intermittent access terminal intake (last 3 days)0.20.20.5-0.10.3-0.30.5-0.50.70.00.70.10.3
Intermittent access total infusions0.10.10.4-0.30.1-0.10.0-0.20.10.60.0-0.6-0.0
Intermittent access day 1 locomotion0.70.83.1-1.40.6-0.60.7-0.80.20.7-0.1-1.80.4
Intermittent access day 15 total locomotion0.20.20.8-0.20.1-0.10.5-0.40.60.90.4-0.2-0.1
Intermittent access total locomotion0.20.30.9-0.60.4-0.40.5-0.50.50.90.3-0.60.0
Intermittent access standard deviation0.60.73.51.1-0.50.5-0.30.30.7-0.10.91.9-0.5
Left kidney weight0.30.81.80.6-0.60.6-1.20.8-1.00.9-1.1-1.3-0.5
Right kidney weight1.02.74.91.9-1.81.8-2.21.8-1.61.2-1.5-0.3-1.5
Cocaine induced anxiety0.80.92.0-0.50.9-0.90.9-0.91.3-0.61.41.00.8
Post-drug Anxiety1.92.23.9-1.51.5-1.51.7-1.72.0-0.31.90.51.2
Baseline Anxiety0.20.20.40.3-0.70.7-0.40.3-0.5-0.1-0.4-0.6-0.2
Tail length2.88.624.9-4.22.0-2.02.6-3.42.42.41.6-5.01.9
Length with tail1.24.524.7-1.7-0.60.60.2-1.00.13.9-0.6-5.0-0.5
Length without tail1.73.66.71.3-2.02.0-1.61.7-1.92.6-2.1-1.3-2.2
Times rat made contact with spout0.40.41.6-0.60.6-0.60.6-0.70.40.00.2-1.30.6
Lifetime Intake0.10.10.7-0.40.1-0.10.1-0.1-0.10.6-0.2-0.8-0.0
Liver weight, left0.20.31.6-0.50.1-0.10.5-0.60.4-0.20.4-1.30.6
Liver weight, right0.50.82.10.5-1.11.1-0.90.5-0.61.1-0.7-1.5-0.6
Locomotor activity0.71.12.8-0.71.5-1.51.1-0.70.9-0.50.81.70.7
Locomotor testing distance0.91.62.6-1.01.6-1.61.5-0.91.0-1.00.91.61.0
Locomotor testing rearing1.32.03.9-1.11.7-1.71.7-1.11.3-1.11.32.01.0
Locomotion in novel chamber1.62.05.2-0.81.3-1.31.1-1.31.2-2.31.3-0.91.9
Locomotion in novel chamber post-restriction0.10.10.4-0.0-0.10.1-0.10.2-0.3-0.2-0.3-0.6-0.1
Fecal boli incidents, locomotor time 11.82.04.21.8-1.31.3-1.51.6-1.10.1-0.92.0-1.4
Change in fecal boli incidents, locomotor task0.90.91.9-1.41.1-1.10.7-1.10.80.10.6-0.90.9
Time >=10cm from walls, locomotor time 12.12.13.2-1.31.8-1.81.4-1.41.4-1.61.40.21.7
Bouts of movement, locomotor time 12.12.37.11.0-1.11.1-1.21.5-1.22.7-1.41.1-2.0
Total resting periods, locomotor time 12.42.66.11.3-1.31.3-1.41.7-1.52.5-1.61.0-2.1
Rest time, locomotor task time 10.40.40.90.5-0.50.5-0.60.6-0.71.0-0.8-0.2-0.7
Distance moved, locomotor task time 12.62.94.6-2.11.6-1.61.7-1.91.5-1.51.5-1.12.0
Vertical activity count, locomotor time 11.21.22.6-1.01.0-1.01.1-1.11.5-0.31.61.10.7
Time >=10cm from walls, locomotor time 20.80.91.4-1.21.2-1.21.1-0.90.4-0.70.3-0.91.1
Bouts of movement, locomotor time 20.20.20.50.20.7-0.70.1-0.20.5-0.10.50.50.3
Total resting periods, locomotor time 20.30.30.60.10.8-0.80.2-0.30.6-0.20.60.50.5
Rest time, locomotor task time 20.30.42.8-0.50.2-0.20.3-0.40.1-0.50.0-1.70.7
Distance moved, locomotor task time 20.30.30.7-0.3-0.40.4-0.40.4-0.70.8-0.8-0.3-0.6
Vertical activity count, locomotor time 20.50.62.7-0.1-0.00.0-0.10.10.31.40.31.6-0.8
Light reinforcement 10.71.32.4-0.41.1-1.11.2-1.01.2-1.51.41.01.2
Light reinforcement 20.91.21.6-1.11.2-1.21.2-1.21.2-0.71.2-0.01.2
Bone: marrow area0.10.30.8-0.10.1-0.1-0.0-0.40.7-0.80.90.00.8
Bone: maximum diameter0.10.31.00.5-0.20.2-0.5-0.00.4-1.00.80.30.5
Bone: maximum force0.40.60.90.8-0.90.9-1.00.9-0.80.5-0.80.3-0.9
Bone: maximum moment0.50.81.10.9-1.01.0-1.01.0-0.90.6-0.90.5-1.0
Mean time between licks in bursts1.82.54.21.6-1.71.7-1.61.6-1.32.1-1.40.2-2.0
Mean num. licks in bursts0.70.81.51.1-1.21.2-1.20.9-0.70.3-0.6-0.4-0.6
Cd content in liver3.63.98.7-1.31.7-1.72.2-1.91.7-2.91.8-1.22.6
Co content in liver0.50.51.6-0.70.7-0.70.9-0.50.70.20.71.30.1
Cu content in liver5.66.810.5-3.22.8-2.82.9-3.13.20.82.9-0.12.0
Fe content in liver1.01.22.3-1.50.9-0.91.3-1.30.90.20.7-1.41.0
K content in liver1.31.37.2-0.3-0.70.7-0.50.5-0.82.7-1.1-0.8-1.3
Mg content in liver1.01.16.2-1.10.1-0.10.4-0.4-0.02.5-0.5-1.5-0.6
Mn content in liver1.61.83.2-1.41.4-1.41.3-1.61.80.21.7-0.11.1
Na content in liver0.30.31.7-0.4-0.20.2-0.20.1-0.31.3-0.4-0.6-0.4
Rb content in liver0.20.31.5-0.80.3-0.31.2-0.50.30.10.20.20.2
Se content in liver0.20.31.3-0.4-0.00.00.1-0.1-0.4-0.9-0.4-1.20.6
Sr content in liver0.40.41.30.2-0.60.6-0.60.2-0.30.9-0.4-1.1-0.4
Zn content in liver0.80.81.4-1.21.1-1.11.0-1.00.7-0.60.6-0.80.9
Bone: minimum diameter0.30.62.20.4-0.90.9-1.00.5-0.7-0.0-0.6-1.5-0.1
Time in familiar zone, hab. session 11.21.12.1-1.21.0-1.01.2-0.90.2-1.40.2-1.41.3
Time in novel zone, hab. session 12.92.85.72.4-1.91.9-2.01.9-1.30.6-1.11.2-1.7
Total zone transitions, hab. session 14.25.89.6-2.72.6-2.62.6-2.93.10.12.90.21.9
Total locomotion distance, hab. session 12.73.96.5-2.12.1-2.12.3-2.32.50.02.40.21.6
Locomotion velocity, hab. session 13.34.77.2-2.62.3-2.32.6-2.62.70.42.50.01.6
Time in familiar zone, hab. session 20.40.42.30.9-0.30.3-0.30.4-0.0-1.50.30.70.3
Time in novel zone, hab. session 20.20.20.7-0.60.2-0.20.3-0.1-0.30.9-0.6-0.5-0.3
Total zone transitions, hab. session 23.14.06.5-2.52.2-2.22.3-2.42.30.22.2-0.11.6
Total locomotion distance, hab. session 20.81.01.8-1.31.0-1.01.3-1.11.20.61.10.30.5
Locomotion velocity, hab. session 20.70.91.8-1.30.9-0.91.2-1.11.10.71.00.10.5
Novel to familiar place preference ratio1.21.23.0-0.81.1-1.11.0-1.10.9-1.71.0-0.21.5
Novelty place preference0.90.92.4-0.71.0-1.00.9-0.90.7-1.50.8-0.11.3
Time in novel zone, NPP test0.90.92.6-0.71.0-1.00.9-0.80.5-1.60.5-0.11.2
Total zone transitions, NPP test3.85.49.6-3.12.6-2.62.9-2.72.60.72.3-0.31.6
Total locomotion distance, NPP test1.52.13.7-1.91.6-1.61.9-1.61.61.31.30.30.5
Locomotion velocity, NPP test1.42.03.4-1.81.4-1.41.7-1.51.61.61.40.30.4
Intraocular pressure0.71.01.7-1.11.2-1.21.0-1.11.30.31.2-0.00.7
Delta distance traveled before/after self-admin1.01.12.31.5-0.90.9-1.01.3-1.3-0.7-1.20.3-0.8
Delta ambulatory time before/after self-admin1.01.22.01.4-1.01.0-1.01.4-1.4-0.7-1.30.3-0.7
Parametrial fat weight0.91.84.3-1.41.1-1.11.0-1.10.3-2.10.3-1.81.8
Pavlov. Cond. lever latency3.13.96.12.1-2.52.5-2.42.1-2.00.8-1.9-0.5-1.8
Pavlov. Cond. magazine entry latency1.41.82.4-0.91.6-1.61.5-1.21.4-1.21.41.31.2
Pavlov. Cond. change in total contacts4.85.27.3-2.32.7-2.72.5-2.52.5-1.32.30.02.3
Pavlov. Cond. index score3.14.06.3-1.92.5-2.52.4-2.02.1-0.92.01.51.6
Pavlov. Cond. latency score2.73.45.7-1.92.4-2.42.3-1.81.9-0.61.71.41.4
Pavlov. Cond. lever contacts4.04.77.5-2.52.7-2.72.7-2.32.3-0.32.00.71.7
Pavlov. Cond. magazine entry number1.82.23.41.3-1.81.8-1.81.5-1.61.0-1.5-1.0-1.3
Pavlov. Cond. intertrial magazine entries0.60.85.2-0.60.3-0.30.4-0.80.6-0.10.5-2.30.9
Pavlov. Cond. lever-magazine prob. diff.3.03.75.9-1.82.4-2.42.3-1.92.0-1.11.91.41.6
Pavlov. Cond. response bias2.93.54.7-1.62.2-2.22.2-1.92.1-1.22.11.41.7
Pavlov. Cond. lever latency2.33.14.3-2.12.1-2.11.8-1.91.2-1.21.0-1.62.1
Pavlov. Cond. magazine entry latency0.81.02.00.9-1.21.2-1.10.7-0.41.4-0.4-0.9-1.0
Pavlov. Cond. change in total contacts1.52.13.51.7-1.61.6-1.31.4-0.71.7-0.61.5-1.9
Pavlov. Cond. index score1.72.13.51.8-1.91.9-1.61.5-0.91.4-0.80.5-1.7
Pavlov. Cond. latency score1.41.73.01.6-1.71.7-1.41.3-0.91.1-0.80.1-1.4
Pavlov. Cond. lever contacts1.62.23.31.6-1.71.7-1.41.6-1.11.2-1.01.4-1.8
Pavlov. Cond. magazine entry number2.53.14.6-1.82.2-2.21.9-1.61.4-1.91.40.81.9
Pavlov. Cond. intertrial magazine entries2.63.46.0-2.32.4-2.42.0-2.01.8-0.11.60.71.5
Pavlov. Cond. lever-magazine prob. diff.2.02.53.91.9-2.02.0-1.71.6-1.01.5-0.90.7-1.9
Pavlov. Cond. response bias1.82.53.71.7-1.91.9-1.51.7-1.31.5-1.20.8-1.9
Time in closed arm before self-admin2.12.43.41.8-1.61.6-1.61.8-1.41.0-1.41.3-1.8
Time in closed arm after self-admin3.53.66.22.2-2.12.1-2.52.1-1.71.5-1.60.5-2.1
Time in open arm before self-admin1.21.32.2-1.20.9-0.91.0-1.10.7-1.50.8-1.31.4
Time in open arm after self-admin0.50.51.1-0.80.8-0.81.1-0.70.7-0.30.60.10.7
Bone: periosteal estimation0.10.10.40.4-0.50.5-0.60.20.0-0.30.20.30.0
Bone: periosteal perimeter0.30.41.21.1-0.70.7-1.10.6-0.1-0.70.20.6-0.1
Bone: post-yield work0.71.02.01.3-1.01.0-1.41.1-0.60.8-0.51.0-1.0
Progressive ratio test 1 active lever presses1.11.12.4-1.61.2-1.21.0-1.10.5-0.60.4-1.21.2
Progressive ratio test 1 breakpoint1.11.12.4-1.61.1-1.11.0-1.10.4-0.60.3-1.51.1
Progressive ratio test 1 inactive lever presses0.10.20.3-0.40.6-0.60.50.0-0.3-0.3-0.40.40.1
Progressive ratio test 2 active lever presses1.71.92.9-1.41.6-1.61.5-1.51.70.21.60.41.0
Progressive ratio test 2 breakpoint1.51.72.8-1.21.5-1.51.3-1.41.70.01.60.71.0
Progressive ratio test 2 inactive lever presses0.30.30.8-0.30.7-0.70.4-0.40.60.90.50.7-0.1
Incentive Sensitization - Responses1.41.43.2-0.61.2-1.21.0-1.11.80.31.81.60.6
Incentive Sensitization - Breakpoint1.41.53.2-0.51.2-1.21.1-1.01.7-0.01.81.70.6
Sum of active levers in priming session hrs 5-61.71.73.8-1.61.0-1.01.3-1.51.0-0.80.9-2.01.4
Progressive ratio0.91.02.4-0.60.9-0.90.9-0.91.0-1.61.1-0.31.4
Food seeking constrained by brief footshock0.30.31.7-0.20.3-0.30.9-0.3-0.0-1.3-0.1-0.50.5
Seeking ratio, punishment vs. effort0.40.41.2-0.2-0.40.4-0.10.4-0.80.9-1.1-0.7-0.8
Retroperitoneal fat weight0.10.31.20.5-0.20.2-0.20.5-0.20.6-0.11.1-0.6
Reaction time number correct1.01.52.51.5-1.11.1-1.51.4-1.6-0.2-1.5-0.8-0.7
Reaction time mean minus median0.50.62.2-1.10.3-0.30.5-0.70.91.50.80.6-0.2
Reaction time mean minus median AUC0.70.92.0-1.40.6-0.60.9-1.11.21.01.0-0.10.3
Reaction time num false alarms1.01.42.2-1.01.5-1.51.2-1.21.4-0.41.40.31.1
Reaction time num false alarms AUC0.91.22.0-1.01.4-1.41.2-1.21.4-0.01.30.40.9
Reaction time trials correct on left1.01.52.51.5-1.11.1-1.51.4-1.6-0.2-1.5-0.8-0.7
Reaction time trials on left1.01.42.31.5-1.11.1-1.51.4-1.5-0.2-1.4-0.7-0.7
Reaction time mean0.40.63.3-0.5-0.10.10.1-0.30.61.80.41.0-0.7
Reaction time mean AUC0.60.74.0-0.70.1-0.10.2-0.40.72.00.61.2-0.7
Median of all reaction times0.20.31.6-0.2-0.10.10.0-0.10.31.30.20.9-0.6
Reaction time omissions0.91.22.4-1.11.2-1.20.9-1.21.50.61.51.00.6
Reaction time false alarm rate1.72.33.8-1.51.8-1.81.7-1.72.00.11.80.71.1
Reaction time premature initiation rate0.30.40.7-0.60.5-0.50.6-0.70.7-0.70.8-0.40.8
Reaction time premature initiations0.10.20.70.3-0.20.2-0.30.1-0.1-0.70.0-0.80.4
Std. dev. reaction times0.60.85.4-0.90.1-0.10.2-0.40.52.30.30.6-0.8
Reaction time trials completed1.01.42.31.5-1.11.1-1.51.4-1.5-0.2-1.4-0.7-0.7
Reaction time trials AUC1.01.42.41.5-1.11.1-1.41.4-1.6-0.3-1.5-0.7-0.7
Run reversals in cocaine runway, females0.30.31.40.1-0.30.3-0.40.3-0.21.2-0.20.5-0.7
Run reversals in cocaine runway, males0.10.10.5-0.10.1-0.10.2-0.10.2-0.70.40.50.3
Latency to leave start box in cocaine runway4.24.610.23.2-2.72.7-2.62.3-2.0-0.7-1.6-0.1-1.5
Latency to leave start box in cocaine runway, F6.36.911.03.3-3.13.1-3.22.9-3.0-0.8-2.7-1.0-1.6
Latency to leave start box in cocaine runway, M0.60.62.40.8-0.10.10.1-0.21.1-0.31.31.5-0.1
Std. dev. time between licks in bursts1.11.43.80.9-0.70.7-0.61.0-0.51.7-0.61.9-1.7
Total sessions with >9 infusions0.30.31.5-0.40.1-0.1-0.1-0.1-0.21.2-0.5-0.9-0.3
Short access day 1 total inactive lever presses0.10.10.5-0.10.3-0.3-0.0-0.20.0-0.2-0.0-0.70.3
Short access day 10 total inactive lever presses0.30.30.80.40.3-0.30.2-0.20.7-0.90.90.90.5
Short access day 1 total infusions0.70.72.0-0.1-0.50.5-0.70.6-1.01.4-1.2-0.5-1.0
Short access day 10 total infusions0.40.51.70.0-0.30.3-0.60.4-0.70.9-0.9-1.3-0.4
Short access total infusions0.80.91.70.3-0.80.8-0.90.8-1.11.3-1.3-0.9-1.0
Short access day 1 locomotion0.20.20.40.3-0.60.6-0.40.3-0.30.7-0.30.1-0.6
Short access day 10 total locomotion0.30.41.4-1.20.4-0.40.6-0.60.20.6-0.0-0.90.2
Short access total locomotion0.60.62.1-0.1-0.60.6-0.40.4-0.71.4-0.9-0.8-0.9
One hour access (0.3 mA shock)0.81.01.8-0.71.0-1.01.1-1.11.3-0.41.30.21.0
Compulsive drug intake2.42.44.2-2.11.6-1.61.5-1.81.3-0.51.2-1.41.7
One hour access (shock baseline)0.30.31.40.70.3-0.30.2-0.00.6-0.50.81.20.2
Social response proportion1.01.12.2-1.51.2-1.21.1-1.20.9-0.30.7-0.91.1
Social responses1.31.73.6-0.81.4-1.41.2-1.01.2-1.91.40.61.5
Social time2.63.55.1-1.62.3-2.32.1-1.61.8-1.81.91.31.8
Soleus weight1.23.54.72.1-2.12.1-1.92.2-2.00.6-1.90.9-2.0
Bone: stiffness0.10.20.40.1-0.40.4-0.50.4-0.60.5-0.7-0.6-0.3
Tibialis anterior weight0.51.73.6-0.30.8-0.81.2-1.11.6-1.81.91.51.2
Time to tail flick, vehicle, before self-admin0.40.40.9-0.91.0-1.00.7-0.70.50.40.30.40.4
Time to tail flick, vehicle, after self-admin0.70.81.51.2-1.11.1-0.91.0-0.90.2-0.8-0.2-0.7
Time to tail flick, test, before self-admin1.71.72.51.3-1.61.6-1.61.5-1.40.6-1.30.3-1.3
Time to tail flick, test, after self-admin1.41.53.11.1-1.21.2-1.21.4-1.70.3-1.8-0.5-1.1
Delta time to tail flick, vehicle, before/after SA1.41.42.51.6-1.41.4-1.31.4-1.2-0.0-1.10.2-1.0
Delta time to tail flick, test, before/after SA0.30.30.7-0.60.6-0.60.7-0.5-0.0-0.5-0.2-0.90.6
Tibia length1.33.64.81.3-2.22.2-1.72.0-2.21.9-2.2-0.0-2.2
Ambulatory time before self-admin4.04.27.4-2.02.1-2.12.0-2.32.6-0.92.70.71.9
Ambulatory time after self-admin0.91.04.9-0.20.8-0.80.7-0.60.7-2.21.0-0.21.2
Bone: tissue strength2.22.13.11.1-1.71.7-1.21.5-1.71.2-1.8-0.8-1.5
Total heroin consumption1.11.34.3-0.80.8-0.81.1-0.90.7-2.10.9-0.81.5
Bone: trabecular number0.61.06.2-0.10.2-0.20.4-0.50.3-2.50.5-1.01.4
Bone: trabecular spacing0.91.25.1-0.41.2-1.21.0-0.61.20.41.12.3-0.0
Bone: trabecular thickness5.66.79.82.9-3.13.1-3.12.9-2.81.2-2.6-0.3-2.4
Bone: trabecular tissue density1.11.56.30.5-1.01.0-0.81.0-1.02.5-1.2-0.0-1.7
Water consumed over 24 hours0.00.00.1-0.10.2-0.20.1-0.20.30.00.3-0.20.2
Number of responses in last shaping day2.12.23.61.9-1.91.9-1.61.5-1.00.7-0.91.1-1.8