Hub : Genes

LOC100912787

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability LOC100912787 0.09 0.07 3.6e-07 0.06 0.07 0.04 0.06 1.0e-06 7.4e-08 3.1e-05 9.3e-07
2 OFC gene expression LOC100912787 0.25 0.15 1.6e-04 0.06 0.05 0.07 0.06 1.9e-02 2.6e-02 1.0e-02 1.9e-02
3 BLA mRNA stability LOC100912787 0.09 0.08 7.0e-04 0.03 0.04 0.03 0.04 1.1e-02 2.4e-03 7.4e-03 5.2e-03
4 NAcc gene expression LOC100912787 0.06 0.05 9.8e-03 0.01 0.01 0.01 0.01 1.3e-02 1.8e-02 1.7e-02 2.1e-02
5 BLA isoform ratio XR_590116.3 0.06 0.05 7.8e-04 0.03 0.06 0.04 0.03 8.2e-03 6.8e-04 4.0e-03 1.3e-02
6 BLA isoform ratio XM_006228763.4 0.06 0.05 8.2e-04 0.03 0.06 0.04 0.03 1.1e-02 6.6e-04 2.4e-03 7.2e-03
7 Brain mRNA stability LOC100912787 0.16 0.1 0.0e+00 0.18 0.17 0.18 0.15 8.7e-17 8.7e-16 8.9e-17 4.6e-14
8 Liver isoform ratio XM_006228763.4 0.03 0.03 2.7e-03 0.01 0.01 0 0.01 3.5e-02 7.7e-03 1.0e-01 2.9e-02
9 PL isoform ratio XM_006228763.4 0.05 0.03 1.4e-08 0.07 0.07 0.07 0.06 4.7e-08 2.3e-08 9.3e-08 1.0e-07
10 PL isoform ratio XR_590116.3 0.05 0.03 5.2e-08 0.06 0.06 0.06 0.06 1.7e-07 1.3e-07 3.2e-07 2.5e-07
11 NAcc intron excision ratio chr1_85074137_85076721 0.02 0.02 2.0e-03 0.01 0.02 0 0.01 1.1e-02 4.1e-03 2.5e-01 1.7e-02
12 Adipose gene expression LOC100912787 0.12 0.1 1.2e-09 0.05 0.06 0.05 0.05 1.1e-06 5.6e-07 2.4e-06 1.3e-06
13 NAcc isoform ratio XM_006228763.4 0.08 0.05 7.3e-13 0.1 0.11 0.11 0.11 1.5e-11 5.8e-13 8.8e-13 1.5e-12
14 pVTA gene expression LOC100912787 0.1 0.08 2.4e-04 0.06 0.08 0.07 0.08 9.1e-04 2.5e-04 6.4e-04 3.0e-04
15 NAcc mRNA stability LOC100912787 0.03 0.03 4.4e-05 0.04 0.04 0.04 0.04 5.8e-05 2.0e-05 4.1e-05 4.2e-05
16 IL gene expression LOC100912787 0.52 0.28 7.7e-03 0.05 0.01 0.03 0.03 2.2e-02 1.6e-01 5.7e-02 5.5e-02
17 BLA gene expression LOC100912787 0.11 0.07 3.0e-07 0.14 0.12 0.12 0.12 5.9e-08 3.3e-07 5.5e-07 3.5e-07
18 Brain isoform ratio XM_006228763.4 0.2 0.08 0.0e+00 0.21 0.14 0.19 0.03 3.2e-19 7.1e-13 2.9e-17 1.0e-03
19 Brain isoform ratio XR_590116.3 0.21 0.11 2.8e-16 0.17 0.1 0.16 0.02 3.0e-15 5.8e-10 1.1e-14 2.5e-03
20 Brain alternative TSS XM_006228762.4 0.04 0.04 3.9e-03 0.03 0.02 0.03 0.01 1.3e-03 2.5e-03 1.7e-03 1.5e-02
21 PL gene expression LOC100912787 0.41 0.21 0.0e+00 0.17 0.18 0.18 0.18 1.1e-18 3.0e-19 2.8e-19 4.9e-19
22 Brain gene expression LOC100912787 0.14 0.08 2.8e-16 0.17 0.17 0.16 0.1 2.2e-15 2.0e-15 9.6e-15 1.1e-09
23 Liver gene expression LOC100912787 0.06 0.06 1.3e-04 0.03 0.03 0.03 0.03 6.0e-04 5.9e-04 2.3e-04 6.7e-04
24 NAcc isoform ratio XR_590116.3 0.11 0.07 1.4e-11 0.1 0.1 0.1 0.1 3.5e-11 9.6e-12 2.9e-11 1.5e-11
25 Brain alternative TSS XM_006228763.4 0.07 0.06 2.8e-05 0.06 0.04 0.05 -0 5.8e-06 7.4e-05 1.2e-05 9.8e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density0.20.31.00.10.00.20.1-0.40.4-0.80.50.5-0.6-0.60.60.70.70.70.4-0.3-0.70.70.8-0.60.9-0.4-1.0-0.3
Area under the delay curve0.80.91.71.3-1.21.1-1.2-1.01.0-0.70.90.9-0.9-0.90.80.80.80.9-1.2-1.1-0.90.90.9-0.90.6-0.5-0.6-0.9
BMI with tail0.31.11.9-1.31.1-1.21.41.1-1.11.1-1.1-1.11.01.1-1.0-1.0-1.0-1.00.90.81.0-1.0-1.01.0-0.90.60.91.0
BMI without tail0.10.21.60.3-0.40.3-0.5-0.40.4-0.20.40.4-0.3-0.30.30.30.30.3-0.5-0.5-0.20.20.1-0.20.3-1.3-0.3-0.3
Body weight2.39.412.02.8-3.13.0-3.0-3.23.2-3.23.23.1-3.1-3.13.23.23.13.1-3.1-3.1-2.82.82.8-2.93.2-3.5-3.1-2.8
Weight adjusted by age0.10.10.6-0.70.5-0.60.50.4-0.40.1-0.3-0.30.30.3-0.2-0.2-0.3-0.30.50.40.3-0.3-0.60.5-0.10.10.00.5
Bone surface1.11.93.11.0-0.91.2-0.8-1.31.3-1.61.41.4-1.4-1.41.51.51.51.5-0.5-1.2-1.71.71.7-1.51.7-1.3-1.8-1.0
Bone volume0.91.52.60.9-0.81.0-0.7-1.21.2-1.51.21.2-1.3-1.31.31.41.41.4-0.5-1.0-1.41.41.5-1.31.6-1.1-1.6-0.9
Breakpoint value in progressive ratio session3.53.86.02.4-2.12.3-2.4-2.02.0-1.92.01.9-1.9-1.91.81.71.91.9-1.8-1.6-2.12.12.1-2.11.6-1.4-1.5-2.0
Number of licking bursts4.04.75.5-2.11.9-2.12.02.2-2.22.3-2.2-2.22.22.2-2.2-2.2-2.2-2.21.72.02.3-2.3-2.32.3-2.32.22.22.3
Context. condit. distance diff. score0.00.00.1-0.10.2-0.10.10.1-0.10.1-0.1-0.10.10.1-0.2-0.1-0.1-0.10.30.00.0-0.0-0.00.0-0.1-0.10.10.1
Locomotion velocity, session 10.70.81.4-0.91.0-0.91.21.0-1.00.7-0.9-0.90.90.9-0.9-0.9-0.8-0.81.10.90.8-0.8-0.60.6-0.80.80.80.8
Locomotion distance, session 10.50.71.50.9-1.10.9-0.7-0.80.8-0.80.80.8-0.8-0.80.80.70.80.7-1.2-0.7-0.90.90.9-0.80.7-0.5-0.6-0.6
Locomotion velocity, session 20.30.30.9-0.60.8-0.60.50.6-0.60.6-0.6-0.60.60.6-0.7-0.6-0.6-0.60.90.40.6-0.6-0.40.4-0.6-0.10.60.4
Locomotion distance, session 21.31.82.4-1.41.3-1.41.61.4-1.41.2-1.4-1.41.41.4-1.3-1.4-1.3-1.41.21.41.2-1.2-1.21.3-1.31.11.31.4
Locomotion velocity, session 30.40.50.8-0.80.9-0.70.60.7-0.70.7-0.7-0.70.70.7-0.7-0.6-0.7-0.70.90.60.7-0.7-0.60.6-0.60.30.50.6
Locomotion distance, session 33.43.75.21.9-1.91.9-2.1-2.02.0-1.91.91.9-1.9-1.91.91.91.91.9-2.0-2.0-1.91.91.8-1.91.9-2.3-1.9-1.9
Stereotopy head waving bouts, day 30.81.02.8-1.21.4-1.11.11.0-1.00.8-1.0-1.00.90.9-0.9-0.9-0.8-0.91.71.10.9-0.9-0.70.8-0.70.50.71.0
Stereotopy head waving duration, day 31.82.15.1-1.62.0-1.61.51.5-1.51.3-1.5-1.51.41.4-1.4-1.4-1.3-1.42.31.51.4-1.4-1.21.3-1.21.01.21.5
Locomotion velocity, session 70.20.20.40.3-0.20.4-0.4-0.40.4-0.60.50.4-0.5-0.50.50.50.50.50.0-0.4-0.60.60.6-0.60.6-0.6-0.6-0.4
Locomotion distance, session 70.10.10.20.2-0.20.2-0.2-0.30.3-0.30.30.3-0.3-0.30.30.30.30.3-0.1-0.2-0.40.40.3-0.30.3-0.3-0.3-0.2
Stereotopy head waving bouts, day 70.80.91.3-0.80.9-0.80.50.9-0.91.0-1.0-1.01.01.0-1.0-1.0-1.0-1.00.80.81.0-1.0-1.11.0-1.10.51.10.8
Stereotopy head waving duration, day 72.22.63.1-1.51.6-1.61.31.6-1.61.6-1.7-1.71.71.7-1.7-1.7-1.7-1.71.51.51.7-1.7-1.71.7-1.71.21.81.5
Locomotion velocity, session 84.14.95.7-2.22.4-2.22.32.3-2.32.2-2.2-2.32.22.2-2.2-2.2-2.2-2.22.42.22.3-2.3-1.92.1-2.12.02.12.4
Locomotion distance, session 80.60.91.1-0.90.9-0.91.01.0-1.01.0-1.0-1.01.01.0-1.0-1.0-1.0-1.00.80.90.9-0.9-0.90.9-1.00.91.01.0
Degree of sensitization distance0.90.91.8-1.01.2-1.01.11.0-1.00.8-0.9-0.90.90.9-0.9-0.9-0.8-0.81.31.00.8-0.8-0.80.8-0.81.10.80.9
Degree of sensitization stereotypy1.01.11.7-0.90.7-0.90.61.0-1.01.2-1.1-1.11.11.1-1.1-1.1-1.2-1.20.51.01.1-1.1-1.31.2-1.30.91.31.1
Conditioned locomotion0.30.40.5-0.50.7-0.50.30.5-0.50.5-0.6-0.70.70.6-0.7-0.7-0.6-0.70.60.40.6-0.6-0.60.6-0.7-0.20.70.7
Cocaine response after cond. corrected0.00.00.10.1-0.10.0-0.20.0-0.00.3-0.1-0.10.10.1-0.1-0.1-0.2-0.1-0.2-0.10.2-0.2-0.20.1-0.2-0.30.2-0.1
Cocaine response after cond. not corrected0.00.00.2-0.00.0-0.0-0.1-0.00.00.10.0-0.00.00.0-0.00.0-0.0-0.00.1-0.20.1-0.1-0.0-0.00.0-0.4-0.0-0.2
Cocaine response before conditioning0.91.12.00.7-0.60.8-0.6-1.01.0-1.21.01.0-1.1-1.11.21.21.21.2-0.4-0.9-1.21.21.3-1.21.4-1.3-1.4-1.0
Saline control response0.10.10.30.4-0.50.4-0.5-0.30.3-0.20.20.2-0.2-0.20.20.10.20.1-0.6-0.4-0.10.10.2-0.20.1-0.30.0-0.2
Bone: connectivity density0.10.20.6-0.10.30.00.3-0.10.2-0.60.30.3-0.4-0.40.40.40.50.50.70.0-0.60.60.6-0.40.7-0.1-0.8-0.0
Bone: cortical apparent density2.33.14.1-1.81.9-1.82.01.8-1.81.6-1.8-1.81.81.8-1.7-1.8-1.7-1.71.71.71.7-1.7-1.61.7-1.71.71.71.8
Bone: cortical area1.42.12.61.5-1.51.5-1.5-1.51.5-1.41.51.5-1.4-1.41.41.51.41.4-1.4-1.5-1.41.41.4-1.31.4-1.6-1.4-1.1
Bone: cortical porosity1.82.03.2-1.61.7-1.51.71.4-1.41.2-1.4-1.41.41.4-1.3-1.3-1.3-1.31.81.81.3-1.3-1.21.3-1.11.41.11.5
Bone: cortical porosity2.42.63.6-1.81.8-1.71.81.6-1.61.5-1.6-1.61.61.6-1.5-1.5-1.5-1.51.91.91.5-1.5-1.41.5-1.41.51.31.7
Bone: cortical thickness0.30.50.80.8-0.80.8-0.8-0.80.8-0.70.70.7-0.7-0.70.70.70.60.7-0.8-0.7-0.60.60.7-0.60.6-0.9-0.6-0.4
Bone: cortical thickness0.91.01.2-1.11.1-1.01.11.0-1.00.9-1.0-1.01.01.0-1.0-1.0-1.0-1.01.11.11.0-1.0-1.01.0-0.90.70.91.0
Bone: cortical tissue density2.73.64.7-2.02.0-2.02.22.0-2.01.8-1.9-1.91.91.9-1.9-1.9-1.8-1.91.81.81.9-1.9-1.81.8-1.81.81.81.9
Condit. Reinf. active minus inactive responses0.20.20.3-0.50.5-0.50.50.5-0.50.5-0.5-0.50.50.4-0.4-0.5-0.4-0.40.40.30.4-0.4-0.40.3-0.40.20.40.2
Condit. Reinf. active-inactive response ratio0.10.10.2-0.40.4-0.40.30.4-0.40.5-0.4-0.40.40.4-0.4-0.4-0.4-0.30.40.20.4-0.4-0.30.3-0.40.10.30.2
Condit. Reinf. active responses1.92.32.9-1.51.5-1.51.71.6-1.61.5-1.6-1.61.61.6-1.6-1.6-1.5-1.61.21.41.5-1.5-1.41.4-1.61.31.61.3
Condit. Reinf. inactive responses1.92.22.9-1.41.3-1.41.71.5-1.51.3-1.6-1.61.61.6-1.5-1.6-1.5-1.61.01.51.4-1.4-1.41.4-1.61.61.71.4
Incentive salience index mean0.10.10.2-0.40.4-0.40.50.4-0.40.4-0.4-0.40.40.4-0.4-0.4-0.3-0.40.30.10.3-0.3-0.30.2-0.3-0.10.40.1
Condit. Reinf. lever presses0.10.10.30.2-0.20.20.0-0.20.2-0.20.20.2-0.2-0.20.20.20.20.2-0.3-0.5-0.30.30.3-0.30.3-0.5-0.2-0.4
Condit. Reinf. active minus inactive responses2.73.36.11.9-1.91.9-2.0-1.81.8-1.71.81.7-1.7-1.71.71.71.71.7-1.9-2.2-1.71.71.6-1.81.6-2.5-1.5-2.1
Condit. Reinf. active-inactive response ratio0.10.10.60.4-0.60.3-0.7-0.20.20.20.10.1-0.0-0.0-0.0-0.0-0.1-0.1-0.8-0.60.0-0.0-0.2-0.0-0.2-0.80.3-0.5
Condit. Reinf. active responses4.66.48.62.5-2.52.6-2.5-2.62.6-2.52.52.5-2.5-2.52.52.52.52.5-2.4-2.7-2.52.52.5-2.52.5-2.9-2.4-2.6
Condit. Reinf. inactive responses4.65.66.92.2-2.22.3-2.1-2.42.4-2.62.42.4-2.5-2.52.52.52.52.5-1.9-2.1-2.52.52.5-2.42.6-2.1-2.6-2.1
Condit. Reinf. lever presses9.112.413.93.7-3.73.7-3.6-3.63.6-3.43.63.6-3.5-3.53.53.53.53.5-3.6-3.6-3.53.53.5-3.53.4-3.4-3.3-3.4
Condit. Reinf. lever reinforcers received4.76.78.92.6-2.62.6-2.6-2.62.6-2.52.62.6-2.5-2.52.52.52.52.5-2.5-2.7-2.52.52.5-2.62.5-3.0-2.4-2.6
Conditioned reinforcement - actives0.10.10.4-0.10.2-0.1-0.10.2-0.20.6-0.3-0.30.30.3-0.3-0.3-0.4-0.4-0.20.40.4-0.4-0.30.4-0.4-0.40.40.4
Conditioned reinforcement - inactives0.80.91.71.1-1.21.1-1.3-1.11.0-0.91.01.0-0.9-0.90.90.90.80.8-1.2-0.9-0.70.70.8-0.80.7-1.1-0.7-0.7
Conditioned locomotion2.12.53.4-1.61.9-1.61.61.6-1.61.4-1.6-1.71.61.6-1.7-1.6-1.6-1.61.61.81.5-1.5-1.41.5-1.61.51.51.4
Patch foraging indifference point 0 sec0.10.10.30.3-0.40.4-0.4-0.50.4-0.20.40.4-0.4-0.40.50.50.40.4-0.40.0-0.20.20.3-0.20.5-0.3-0.5-0.0
Patch foraging indifference point AUC0.50.60.8-0.90.8-0.90.80.8-0.80.7-0.8-0.80.80.8-0.7-0.7-0.8-0.80.70.70.7-0.7-0.90.8-0.7-0.10.70.7
Delay disc. indifference point, 0s delay0.60.61.91.2-1.01.0-1.2-0.70.7-0.40.60.6-0.5-0.50.50.40.50.5-1.3-1.1-0.80.80.7-0.70.2-1.4-0.1-0.7
Delay disc. indifference point, 16s delay2.42.44.12.0-1.71.8-1.9-1.61.6-1.11.51.5-1.4-1.51.41.41.31.4-2.0-1.8-1.51.51.6-1.61.1-1.6-1.1-1.5
Delay disc. indifference point, 2s delay1.21.32.21.4-1.41.3-1.5-1.21.2-1.21.11.2-1.1-1.11.11.01.11.1-1.4-1.2-1.11.11.0-1.00.9-0.8-0.8-0.9
Delay disc. indifference point, 24s delay2.82.73.21.7-1.81.7-1.6-1.71.7-1.61.71.7-1.7-1.71.71.71.71.7-1.7-1.7-1.61.61.7-1.71.6-1.3-1.6-1.7
Delay disc. indifference point, 4s delay0.10.10.30.5-0.50.4-0.5-0.20.20.30.10.1-0.1-0.10.00.0-0.00.0-0.5-0.3-0.10.10.0-0.0-0.2-0.00.2-0.0
Delay disc. indifference point, 8s delay0.20.20.50.4-0.30.3-0.1-0.30.3-0.20.40.4-0.4-0.40.40.40.40.50.1-0.2-0.40.40.5-0.50.50.7-0.5-0.4
Indifference point function ln k0.60.81.11.0-0.81.0-0.9-0.90.9-0.90.90.9-0.9-0.90.90.80.90.9-0.9-0.8-0.80.81.1-1.10.8-0.3-0.8-1.0
Indifference point function log k0.60.81.11.0-0.81.0-0.9-0.90.9-0.90.90.9-0.9-0.90.90.80.90.9-0.9-0.8-0.80.81.1-1.10.8-0.3-0.8-1.0
Patch foraging total patch changes 0 sec0.20.30.50.5-0.70.6-0.5-0.60.6-0.40.60.6-0.6-0.60.60.70.60.6-0.7-0.2-0.40.40.5-0.40.6-0.3-0.7-0.2
Patch foraging total patch changes 12 sec0.10.11.50.4-0.30.4-0.4-0.30.3-0.00.30.3-0.2-0.30.20.30.20.3-0.4-0.3-0.40.40.3-0.30.2-1.2-0.3-0.3
Patch foraging total patch changes 18 sec0.10.20.5-0.60.5-0.50.60.4-0.40.4-0.3-0.30.30.3-0.3-0.2-0.3-0.30.50.70.4-0.4-0.50.5-0.2-0.10.10.7
Patch foraging total patch changes 24 sec0.60.81.70.9-1.10.9-0.9-0.90.9-0.60.90.9-0.9-0.90.90.90.80.9-1.1-0.9-0.70.70.6-0.70.8-1.3-0.8-0.8
Patch foraging total patch changes 6 sec0.00.00.3-0.2-0.1-0.10.0-0.10.10.00.10.1-0.1-0.10.10.20.00.1-0.00.30.3-0.3-0.10.20.2-0.5-0.20.3
Patch foraging time to switch 0 sec0.30.51.3-0.51.0-0.60.60.8-0.71.1-0.7-0.70.70.7-0.7-0.7-0.7-0.71.10.40.4-0.4-0.40.5-0.70.30.70.5
Patch foraging water rate 0 sec0.91.42.4-1.31.0-1.21.21.1-1.10.7-1.1-1.11.11.1-1.1-1.1-1.1-1.11.11.41.5-1.5-1.31.4-1.11.51.01.4
Patch foraging water rate 12 sec0.30.51.70.6-1.20.6-1.0-0.80.8-1.00.70.7-0.7-0.70.70.70.60.6-1.3-0.8-0.00.00.1-0.20.5-0.3-0.5-0.6
Patch foraging water rate 18 sec0.30.32.6-0.40.1-0.40.30.3-0.3-0.0-0.4-0.40.40.4-0.4-0.5-0.4-0.40.40.80.7-0.7-0.70.7-0.51.60.60.6
Patch foraging water rate 24 sec0.00.00.30.2-0.40.1-0.3-0.10.1-0.20.10.1-0.0-0.0-0.0-0.0-0.1-0.0-0.40.00.2-0.2-0.20.1-0.20.50.20.1
Patch foraging water rate 6 sec0.50.81.70.6-0.90.7-0.6-1.00.9-1.31.01.0-1.0-1.01.01.01.01.0-0.7-0.9-0.50.50.6-0.71.10.1-1.1-0.9
Seeking ratio, delayed vs. immediate footshock1.21.42.11.4-1.31.3-1.3-1.21.2-0.51.21.2-1.1-1.11.11.21.01.1-1.4-1.4-1.21.21.2-1.21.0-0.8-1.0-1.2
Distance traveled before self-admin0.40.41.41.2-0.91.0-0.9-0.60.6-0.20.50.5-0.4-0.40.40.40.40.4-1.1-0.6-0.80.80.8-0.80.2-0.7-0.1-0.7
Distance traveled after self-admin5.05.67.12.5-2.72.5-2.3-2.42.4-2.52.42.4-2.4-2.32.42.32.32.3-2.5-2.1-2.22.22.4-2.32.2-2.5-2.2-2.2
Extensor digitorum longus weight0.20.81.1-0.90.9-0.90.80.9-0.90.9-0.9-0.90.90.9-0.9-0.9-0.9-0.90.90.81.0-1.0-1.01.0-0.90.80.91.0
Bone: elastic displacement0.00.00.1-0.00.1-0.00.10.0-0.0-0.0-0.0-0.00.00.0-0.0-0.0-0.0-0.00.10.30.1-0.10.00.1-0.00.3-0.00.3
Bone: elastic work1.82.32.71.5-1.41.5-1.4-1.51.5-1.51.51.5-1.5-1.51.51.61.51.5-1.4-1.3-1.51.51.6-1.61.6-1.5-1.6-1.4
Bone: endosteal estimation1.73.84.21.9-1.91.9-1.8-1.92.0-2.02.02.0-2.0-2.02.02.02.02.0-1.8-2.0-2.12.12.0-2.02.0-1.8-2.0-1.8
Bone: endosteal perimeter1.93.84.72.0-2.02.0-2.0-2.02.0-1.92.01.9-1.9-1.91.91.91.91.9-2.0-2.2-2.02.01.9-1.91.9-2.0-1.8-1.9
Epididymis fat weight0.00.00.1-0.20.0-0.10.3-0.00.0-0.20.10.1-0.1-0.10.20.10.20.10.0-0.1-0.10.10.1-0.10.30.2-0.3-0.0
Delta time in closed arm before/after self-admin2.01.92.81.1-1.21.3-0.9-1.41.4-1.51.41.4-1.5-1.51.51.51.61.5-0.9-1.2-1.41.41.6-1.51.7-0.9-1.7-1.5
Delta time in open arm before/after self-admin1.21.12.3-1.30.7-1.21.01.0-1.00.9-1.0-1.01.01.0-1.0-1.0-1.1-1.10.40.61.2-1.2-1.51.4-1.01.01.01.2
Diff in mean of infusions in LGA sessions0.10.10.50.7-0.40.5-0.6-0.20.20.20.10.1-0.0-0.0-0.0-0.10.0-0.0-0.4-0.1-0.30.30.3-0.3-0.3-0.20.4-0.3
Delay discount exponential model param0.90.91.6-1.31.2-1.11.21.0-1.00.7-1.0-1.01.01.0-0.9-0.9-0.9-0.91.21.10.9-0.9-0.90.9-0.70.50.70.9
Extinction: sum of active levers before priming3.33.34.51.6-1.51.7-1.3-1.71.7-2.11.81.8-1.8-1.81.91.82.01.9-1.4-1.5-2.12.12.0-2.02.0-1.2-2.0-2.1
Active lever presses in extinction session 63.53.44.91.7-1.31.8-1.6-1.81.8-2.21.81.8-1.8-1.91.81.82.01.9-1.1-1.5-2.12.12.1-2.12.0-2.0-1.9-1.9
Bone: final force1.52.42.91.5-1.41.5-1.4-1.61.6-1.61.61.6-1.6-1.61.61.71.61.6-1.4-1.3-1.61.61.7-1.61.7-1.5-1.7-1.4
Bone: final moment2.03.23.71.7-1.71.8-1.6-1.81.8-1.91.81.8-1.8-1.81.91.91.81.8-1.7-1.6-1.81.81.9-1.81.9-1.7-1.9-1.6
Food consumed during 24 hour testing period0.81.01.11.0-1.01.0-1.0-1.01.0-1.01.01.0-1.0-1.01.01.01.01.0-1.0-1.0-0.90.91.1-1.01.0-0.7-1.0-0.9
Glucose0.20.30.4-0.60.5-0.60.50.6-0.60.5-0.6-0.60.60.6-0.6-0.6-0.6-0.60.60.60.6-0.6-0.50.6-0.60.60.60.6
Heart weight0.20.30.90.4-0.30.5-0.7-0.60.6-1.00.50.5-0.5-0.50.50.50.50.5-0.3-0.7-0.40.40.3-0.40.5-0.5-0.5-0.7
Delay discount hyperbolic model param0.70.71.4-1.21.1-1.01.10.9-0.90.6-0.9-0.90.80.8-0.8-0.8-0.7-0.81.11.00.8-0.8-0.80.8-0.60.40.60.7
Intermittent access intake day 1-15 change1.61.62.51.1-1.41.2-1.4-1.41.3-1.21.31.3-1.3-1.31.31.31.31.3-1.6-1.2-1.11.11.0-1.11.3-1.3-1.3-1.1
Intermittent access intake escalation1.51.52.11.0-1.31.1-1.4-1.31.3-1.21.31.3-1.3-1.31.31.31.31.2-1.4-1.2-1.11.11.0-1.11.3-1.2-1.3-1.1
Intermittent access intake escalation 22.01.93.41.5-1.61.4-1.6-1.51.4-1.01.41.4-1.4-1.41.41.41.31.3-1.8-1.5-1.21.21.2-1.31.2-1.6-1.2-1.2
Intermitt. access day 1 inactive lever presses3.84.15.41.7-1.71.8-1.4-1.91.9-2.22.02.0-2.1-2.12.12.12.22.2-1.4-2.0-2.22.22.2-2.22.3-1.4-2.3-2.2
Intermitt. access day 15 inactive lever presses0.70.81.11.0-1.00.9-1.0-0.90.9-0.70.90.9-0.9-0.90.90.90.80.9-0.8-1.0-0.90.90.8-0.80.8-0.9-0.8-0.9
Intermitt. access escalation Index0.10.10.70.1-0.1-0.00.00.1-0.20.0-0.2-0.20.20.2-0.3-0.3-0.3-0.3-0.10.20.3-0.3-0.30.3-0.40.90.50.3
Intermittent access day 1 total infusions1.92.23.0-1.11.2-1.31.21.5-1.51.7-1.5-1.51.61.6-1.6-1.6-1.6-1.61.01.61.5-1.5-1.51.5-1.71.71.71.5
Intermittent access day 15 total infusions0.10.10.50.4-0.40.2-0.5-0.10.10.40.00.00.00.0-0.1-0.0-0.1-0.1-0.7-0.00.0-0.0-0.10.1-0.3-0.10.30.0
Intermittent access terminal intake (last 3 days)0.10.10.60.4-0.40.2-0.50.0-0.00.7-0.2-0.20.20.2-0.3-0.3-0.4-0.3-0.80.10.2-0.2-0.30.3-0.6-0.20.60.2
Intermittent access total infusions0.30.30.7-0.10.1-0.20.10.4-0.40.9-0.5-0.50.60.6-0.6-0.6-0.7-0.6-0.20.60.5-0.5-0.50.5-0.80.50.80.5
Intermittent access day 1 locomotion0.70.71.1-0.70.9-0.80.90.9-0.90.8-0.9-0.90.90.9-0.9-0.9-0.9-0.90.81.00.7-0.7-0.70.7-0.90.80.90.7
Intermittent access day 15 total locomotion0.00.00.2-0.30.3-0.20.20.2-0.2-0.0-0.2-0.20.20.2-0.2-0.2-0.1-0.20.30.50.2-0.2-0.20.2-0.10.30.10.2
Intermittent access total locomotion1.01.11.6-1.01.1-1.01.01.1-1.11.0-1.1-1.11.11.1-1.1-1.1-1.1-1.10.91.30.9-0.9-1.01.0-1.00.91.00.9
Intermittent access standard deviation6.06.48.22.7-2.82.6-2.7-2.62.6-2.32.62.6-2.5-2.52.52.52.52.5-2.9-2.4-2.42.42.5-2.52.3-2.1-2.4-2.4
Left kidney weight1.74.76.81.6-1.81.8-1.6-2.22.1-2.52.22.2-2.2-2.22.42.42.32.3-1.7-2.2-2.12.12.1-2.12.6-2.3-2.6-2.1
Right kidney weight3.911.013.12.9-3.23.1-2.9-3.33.3-3.63.43.4-3.4-3.43.53.53.43.4-2.9-3.2-3.33.33.3-3.33.6-3.1-3.6-3.3
Cocaine induced anxiety0.60.71.10.8-0.60.8-0.6-0.70.8-0.80.80.8-0.8-0.80.80.80.90.9-0.2-0.9-1.01.01.0-1.00.9-1.0-0.8-0.9
Post-drug Anxiety0.10.10.90.3-0.00.2-0.2-0.10.10.20.10.1-0.1-0.10.10.10.10.10.3-0.4-0.30.30.2-0.20.0-0.9-0.0-0.3
Baseline Anxiety1.11.21.8-1.11.1-1.11.11.1-1.11.3-1.1-1.11.11.1-1.1-1.1-1.2-1.10.71.01.2-1.2-1.21.2-1.10.61.11.2
Tail length5.115.418.94.0-4.34.0-4.3-4.24.1-4.04.04.0-4.0-4.04.04.03.93.9-4.1-3.8-3.63.63.5-3.63.8-4.0-3.7-3.7
Length with tail8.129.734.35.5-5.75.5-5.9-5.75.7-5.75.65.6-5.6-5.65.55.65.55.5-5.3-5.3-5.15.15.1-5.15.4-5.4-5.3-5.2
Length without tail4.39.411.92.8-3.23.0-3.0-3.23.2-3.43.23.2-3.2-3.23.33.33.23.2-2.8-3.0-2.82.83.0-2.93.3-2.4-3.3-2.8
Times rat made contact with spout1.21.42.0-1.31.2-1.21.31.2-1.21.2-1.2-1.21.11.2-1.1-1.1-1.1-1.11.11.41.3-1.3-1.11.2-1.01.31.01.3
Lifetime Intake0.60.61.2-0.50.6-0.60.50.8-0.81.1-0.8-0.80.90.8-0.9-0.8-0.9-0.90.30.90.7-0.7-0.70.7-1.00.81.00.7
Liver weight, left0.61.01.7-1.11.0-1.11.11.0-1.01.0-1.0-1.01.01.0-1.0-0.9-1.0-1.01.11.31.1-1.1-1.01.0-0.90.80.81.1
Liver weight, right0.10.20.4-0.40.3-0.40.30.3-0.30.3-0.3-0.30.30.4-0.3-0.3-0.4-0.40.10.60.6-0.6-0.60.6-0.40.00.40.6
Locomotor activity0.50.71.6-1.01.1-0.91.10.9-0.90.6-0.8-0.90.80.8-0.8-0.8-0.7-0.81.21.00.8-0.8-0.60.7-0.60.80.61.0
Locomotor testing distance0.50.81.5-1.11.2-1.01.21.0-0.90.8-0.9-0.90.90.9-0.8-0.8-0.8-0.81.20.90.8-0.8-0.70.7-0.71.00.71.0
Locomotor testing rearing2.64.05.0-2.12.0-2.11.82.0-2.02.0-2.0-2.02.02.0-2.0-2.0-2.0-2.02.11.72.2-2.2-2.12.1-2.01.52.02.2
Locomotion in novel chamber0.00.00.20.10.20.00.20.1-0.1-0.0-0.1-0.10.10.0-0.1-0.10.0-0.00.10.1-0.30.30.2-0.2-0.00.40.1-0.1
Locomotion in novel chamber post-restriction0.60.71.71.3-0.71.1-1.0-0.70.7-0.40.70.7-0.7-0.70.60.60.70.7-1.0-0.9-1.11.11.2-1.10.5-0.6-0.5-1.0
Fecal boli incidents, locomotor time 10.91.01.8-0.91.2-0.91.11.1-1.10.8-1.1-1.11.11.0-1.1-1.2-0.9-1.01.31.10.6-0.6-0.70.8-1.11.21.10.8
Change in fecal boli incidents, locomotor task0.10.10.20.1-0.30.2-0.3-0.30.3-0.10.30.3-0.3-0.30.30.30.30.3-0.2-0.4-0.20.20.1-0.20.3-0.2-0.3-0.3
Time >=10cm from walls, locomotor time 10.00.00.3-0.10.2-0.20.20.2-0.20.5-0.2-0.20.20.2-0.2-0.1-0.2-0.20.30.10.2-0.2-0.20.1-0.20.50.20.1
Bouts of movement, locomotor time 11.41.53.21.8-1.61.6-1.8-1.31.3-1.01.21.2-1.2-1.21.01.01.11.1-1.5-1.4-1.11.11.2-1.10.7-1.0-0.7-1.1
Total resting periods, locomotor time 11.51.63.51.9-1.51.6-1.8-1.31.3-1.01.21.2-1.2-1.21.11.01.11.1-1.5-1.4-1.21.21.3-1.30.8-1.1-0.7-1.2
Rest time, locomotor task time 10.20.20.7-0.20.4-0.20.20.5-0.40.3-0.5-0.60.60.5-0.6-0.7-0.5-0.60.10.20.4-0.4-0.30.3-0.7-0.00.80.3
Distance moved, locomotor task time 10.10.10.2-0.40.4-0.30.20.2-0.20.3-0.2-0.20.20.2-0.2-0.1-0.2-0.20.40.30.3-0.3-0.40.4-0.1-0.30.00.4
Vertical activity count, locomotor time 10.90.91.70.5-0.90.7-0.8-1.11.0-1.11.11.1-1.1-1.11.11.21.11.1-0.6-0.9-0.90.90.7-0.71.3-0.7-1.3-0.8
Time >=10cm from walls, locomotor time 20.90.91.8-0.50.5-0.70.60.9-0.91.2-1.0-1.01.01.0-1.1-1.1-1.1-1.10.20.71.1-1.1-1.01.0-1.30.61.31.0
Bouts of movement, locomotor time 20.10.10.70.6-0.30.4-0.8-0.30.30.00.20.2-0.1-0.20.00.10.10.1-0.4-0.4-0.20.20.1-0.1-0.1-0.50.1-0.2
Total resting periods, locomotor time 20.00.00.30.3-0.10.2-0.6-0.10.10.10.00.0-0.0-0.0-0.1-0.1-0.0-0.0-0.2-0.20.0-0.0-0.00.0-0.2-0.30.2-0.0
Rest time, locomotor task time 20.10.10.3-0.20.0-0.20.00.2-0.20.2-0.3-0.30.30.3-0.4-0.4-0.3-0.4-0.10.20.3-0.3-0.40.3-0.50.40.50.2
Distance moved, locomotor task time 20.40.51.0-0.70.6-0.70.40.6-0.60.8-0.6-0.60.60.6-0.6-0.6-0.7-0.60.50.60.8-0.8-0.80.8-0.6-0.40.51.0
Vertical activity count, locomotor time 20.40.50.90.6-0.70.6-0.7-0.70.7-0.70.70.7-0.7-0.70.70.70.70.7-0.6-0.8-0.60.60.3-0.40.7-1.0-0.7-0.5
Light reinforcement 10.10.30.6-0.60.4-0.60.50.5-0.50.6-0.5-0.50.50.5-0.4-0.4-0.5-0.50.30.50.6-0.6-0.60.6-0.40.80.40.6
Light reinforcement 22.83.86.1-2.22.3-2.12.12.1-2.01.6-2.0-2.01.91.9-1.9-1.9-1.8-1.92.51.91.7-1.7-1.81.8-1.72.31.71.8
Bone: marrow area1.83.94.41.9-2.02.0-1.8-2.02.0-2.12.02.0-2.0-2.02.02.02.02.0-1.8-2.0-2.12.12.1-2.02.0-1.8-2.0-1.8
Bone: maximum diameter1.42.53.51.5-1.51.5-1.6-1.61.6-1.61.61.6-1.6-1.61.61.61.61.6-1.4-1.7-1.61.61.6-1.51.6-1.9-1.7-1.2
Bone: maximum force2.54.44.72.1-2.12.1-2.0-2.12.1-2.12.12.1-2.1-2.12.12.22.12.1-2.1-1.9-2.12.12.2-2.12.1-1.9-2.1-1.9
Bone: maximum moment3.15.35.62.3-2.42.3-2.2-2.32.3-2.32.32.3-2.3-2.32.32.42.32.3-2.4-2.2-2.32.32.4-2.32.3-2.2-2.3-2.2
Mean time between licks in bursts0.00.00.20.1-0.20.1-0.2-0.20.2-0.10.20.2-0.1-0.10.10.20.10.1-0.1-0.4-0.10.10.1-0.10.2-0.4-0.2-0.2
Mean num. licks in bursts1.01.31.71.0-0.81.1-0.9-1.11.1-1.31.11.1-1.1-1.11.21.21.21.2-0.7-0.9-1.21.21.3-1.21.3-1.2-1.3-1.2
Cd content in liver0.00.00.4-0.20.1-0.10.30.1-0.1-0.1-0.0-0.00.00.00.0-0.00.00.00.20.2-0.00.00.00.00.10.6-0.10.3
Co content in liver0.60.71.9-1.11.1-1.01.30.9-0.90.6-0.8-0.80.80.8-0.7-0.7-0.7-0.71.40.70.8-0.8-0.70.7-0.50.90.50.7
Cu content in liver0.30.40.90.7-0.90.7-0.7-0.80.7-0.60.70.7-0.7-0.70.70.70.60.6-0.9-0.4-0.50.50.5-0.40.6-0.6-0.6-0.3
Fe content in liver0.00.00.1-0.10.1-0.10.20.1-0.10.1-0.1-0.10.10.1-0.1-0.1-0.1-0.10.10.1-0.00.0-0.00.0-0.10.30.10.0
K content in liver0.10.10.60.1-0.20.2-0.2-0.20.2-0.20.20.2-0.2-0.20.20.30.20.2-0.3-0.3-0.10.10.1-0.10.3-0.8-0.3-0.2
Mg content in liver0.40.40.6-0.70.6-0.60.60.6-0.60.7-0.6-0.60.60.6-0.6-0.6-0.6-0.60.50.70.7-0.7-0.70.7-0.60.20.50.8
Mn content in liver0.80.91.4-1.11.0-1.01.10.9-0.90.8-0.9-1.01.01.0-0.9-0.9-0.9-1.00.91.21.0-1.0-1.01.0-0.90.50.81.2
Na content in liver2.22.35.11.6-1.71.6-1.9-1.51.5-1.11.51.4-1.4-1.41.41.41.31.3-1.8-1.9-1.21.21.2-1.41.2-2.3-1.2-1.8
Rb content in liver0.00.00.00.0-0.0-0.0-0.10.0-0.00.2-0.1-0.10.10.1-0.1-0.1-0.1-0.1-0.10.10.2-0.2-0.20.1-0.20.20.20.2
Se content in liver8.19.911.0-3.23.2-3.23.33.2-3.23.1-3.2-3.23.23.2-3.1-3.1-3.1-3.13.03.33.1-3.1-3.13.2-3.03.03.03.2
Sr content in liver0.80.81.3-0.91.0-0.91.00.9-0.90.8-0.9-0.90.90.9-0.9-0.9-0.8-0.81.10.80.8-0.8-0.80.8-0.81.00.80.8
Zn content in liver0.20.20.4-0.50.4-0.50.60.4-0.40.4-0.4-0.40.40.4-0.3-0.3-0.4-0.30.50.30.5-0.5-0.40.4-0.30.50.20.4
Bone: minimum diameter4.07.48.62.9-2.92.8-2.9-2.82.8-2.62.72.7-2.7-2.72.72.72.62.6-2.9-2.9-2.62.62.6-2.62.5-2.9-2.5-2.6
Time in familiar zone, hab. session 10.30.30.40.5-0.60.5-0.5-0.50.5-0.50.50.5-0.5-0.50.50.50.50.5-0.6-0.5-0.60.60.5-0.50.4-0.6-0.4-0.6
Time in novel zone, hab. session 10.90.91.2-0.80.7-0.80.50.8-0.91.1-0.9-0.90.90.9-0.9-0.9-1.0-1.00.71.01.0-1.0-1.11.1-1.01.01.01.0
Total zone transitions, hab. session 10.00.10.60.3-0.50.3-0.3-0.10.1-0.10.10.1-0.1-0.00.10.00.00.0-0.8-0.2-0.30.30.2-0.2-0.1-0.20.1-0.3
Total locomotion distance, hab. session 12.23.16.02.0-2.21.9-2.0-1.81.8-1.61.71.7-1.6-1.61.61.61.61.6-2.5-1.7-1.91.91.6-1.71.4-1.5-1.3-1.8
Locomotion velocity, hab. session 11.31.83.31.5-1.61.4-1.3-1.31.3-1.31.31.3-1.3-1.31.31.21.31.2-1.8-1.3-1.41.41.3-1.41.1-1.2-1.1-1.4
Time in familiar zone, hab. session 22.72.83.41.6-1.51.6-1.7-1.71.7-1.91.71.7-1.7-1.71.71.71.81.7-1.2-1.6-1.71.71.7-1.71.7-1.6-1.7-1.6
Time in novel zone, hab. session 21.71.72.1-1.21.1-1.31.31.3-1.31.5-1.3-1.31.31.3-1.3-1.3-1.4-1.30.91.41.3-1.3-1.41.3-1.41.41.41.2
Total zone transitions, hab. session 22.53.24.4-1.61.3-1.71.51.8-1.82.0-1.9-1.91.91.9-1.9-1.9-2.0-2.01.01.61.8-1.8-1.91.9-2.01.42.11.8
Total locomotion distance, hab. session 20.00.00.20.1-0.30.1-0.2-0.0-0.00.2-0.1-0.10.10.1-0.1-0.1-0.2-0.2-0.50.00.1-0.1-0.20.1-0.30.10.30.0
Locomotion velocity, hab. session 20.00.10.2-0.1-0.1-0.10.10.2-0.20.3-0.2-0.30.30.3-0.3-0.3-0.3-0.3-0.20.20.2-0.2-0.30.3-0.40.20.40.2
Novel to familiar place preference ratio0.20.20.90.5-0.80.5-0.6-0.50.5-0.20.40.4-0.4-0.40.40.40.30.3-1.0-0.5-0.30.30.2-0.20.3-0.6-0.3-0.2
Novelty place preference0.10.10.80.4-0.70.4-0.5-0.40.4-0.10.30.3-0.3-0.30.30.30.20.2-0.9-0.4-0.20.20.1-0.10.1-0.5-0.1-0.1
Time in novel zone, NPP test0.00.00.40.2-0.40.2-0.3-0.10.10.10.10.1-0.0-0.00.10.1-0.1-0.0-0.6-0.20.0-0.0-0.10.1-0.1-0.30.10.1
Total zone transitions, NPP test0.10.10.3-0.30.2-0.30.50.4-0.40.2-0.3-0.30.30.3-0.3-0.3-0.3-0.30.10.50.1-0.1-0.20.3-0.30.60.30.4
Total locomotion distance, NPP test2.73.74.22.0-2.02.0-1.9-1.91.9-2.01.91.9-1.9-1.91.91.91.91.9-2.0-1.7-2.02.02.0-1.91.9-1.6-1.9-1.7
Locomotion velocity, NPP test3.04.24.92.1-2.22.1-2.0-2.12.1-2.12.12.1-2.1-2.12.12.02.12.0-2.2-1.8-2.22.22.1-2.12.0-1.7-2.0-1.9
Intraocular pressure0.00.00.10.3-0.30.2-0.2-0.10.1-0.10.10.1-0.1-0.10.10.00.10.1-0.2-0.1-0.40.40.1-0.1-0.00.10.1-0.3
Delta distance traveled before/after self-admin3.74.05.81.7-1.91.8-1.8-2.12.1-2.42.12.1-2.1-2.12.22.22.12.1-1.4-1.8-1.81.81.8-1.82.2-2.1-2.3-1.8
Delta ambulatory time before/after self-admin3.53.96.71.5-1.81.7-1.6-2.12.0-2.62.12.1-2.2-2.12.22.22.22.2-1.3-1.5-1.71.71.8-1.82.4-1.9-2.4-1.7
Parametrial fat weight0.40.82.3-1.41.3-1.21.30.9-0.90.4-0.8-0.80.70.7-0.6-0.6-0.6-0.61.51.00.9-0.9-0.70.7-0.30.60.20.7
Pavlov. Cond. lever latency0.10.10.30.4-0.30.4-0.5-0.40.4-0.40.40.4-0.4-0.40.40.30.40.4-0.2-0.4-0.30.30.4-0.40.3-0.3-0.3-0.5
Pavlov. Cond. magazine entry latency0.30.41.2-0.50.4-0.50.40.6-0.60.8-0.6-0.60.60.6-0.6-0.6-0.7-0.70.30.80.7-0.7-0.70.8-0.81.10.80.8
Pavlov. Cond. change in total contacts0.10.10.3-0.30.1-0.30.30.3-0.40.5-0.4-0.40.40.4-0.4-0.4-0.5-0.40.00.20.4-0.4-0.50.4-0.50.50.50.2
Pavlov. Cond. index score0.40.50.7-0.70.5-0.70.70.7-0.70.8-0.7-0.70.70.7-0.7-0.7-0.8-0.70.50.80.7-0.7-0.80.8-0.70.80.70.8
Pavlov. Cond. latency score0.20.20.3-0.40.4-0.40.40.4-0.40.5-0.5-0.50.50.5-0.5-0.4-0.5-0.50.30.40.4-0.4-0.50.5-0.50.40.50.5
Pavlov. Cond. lever contacts0.10.10.30.3-0.40.3-0.3-0.40.3-0.20.30.3-0.3-0.30.30.30.30.3-0.5-0.3-0.30.30.3-0.20.3-0.4-0.3-0.2
Pavlov. Cond. magazine entry number0.50.61.20.6-0.50.7-0.5-0.70.7-0.90.70.7-0.8-0.80.80.80.80.8-0.3-0.9-0.80.80.9-0.90.9-1.1-0.9-0.9
Pavlov. Cond. intertrial magazine entries0.60.81.0-0.90.9-0.90.90.9-0.90.9-0.9-1.00.90.9-1.0-1.0-0.9-1.00.80.41.0-1.0-1.00.8-0.90.11.00.4
Pavlov. Cond. lever-magazine prob. diff.0.50.70.9-0.70.5-0.80.70.8-0.80.9-0.8-0.80.80.8-0.8-0.8-0.9-0.80.50.90.8-0.8-0.90.9-0.90.90.90.9
Pavlov. Cond. response bias0.10.10.2-0.20.0-0.20.20.2-0.20.4-0.3-0.30.30.3-0.3-0.3-0.3-0.3-0.10.40.3-0.3-0.40.4-0.40.50.40.4
Pavlov. Cond. lever latency5.37.27.7-2.72.7-2.72.62.7-2.72.6-2.7-2.72.72.7-2.7-2.7-2.7-2.72.52.82.7-2.7-2.72.7-2.72.72.62.7
Pavlov. Cond. magazine entry latency3.64.14.32.1-2.02.1-1.9-2.02.1-2.12.12.1-2.1-2.12.02.02.12.0-2.0-2.1-2.02.02.1-2.12.0-2.0-2.0-2.0
Pavlov. Cond. change in total contacts9.112.514.43.6-3.63.6-3.7-3.63.6-3.43.63.6-3.5-3.53.53.53.53.5-3.5-3.8-3.43.43.4-3.53.4-3.8-3.4-3.7
Pavlov. Cond. index score5.67.27.72.7-2.72.7-2.6-2.72.7-2.62.72.7-2.7-2.72.72.72.72.7-2.6-2.8-2.72.72.7-2.72.6-2.6-2.6-2.7
Pavlov. Cond. latency score5.46.77.32.6-2.62.6-2.5-2.62.6-2.62.62.6-2.6-2.62.62.62.62.6-2.5-2.7-2.62.62.6-2.62.6-2.6-2.5-2.6
Pavlov. Cond. lever contacts4.76.47.12.6-2.62.6-2.5-2.62.6-2.42.52.6-2.5-2.52.52.52.52.5-2.5-2.7-2.52.52.4-2.52.4-2.5-2.4-2.6
Pavlov. Cond. magazine entry number3.84.75.4-2.22.2-2.22.02.2-2.22.2-2.2-2.22.22.2-2.2-2.1-2.2-2.22.22.32.1-2.1-2.22.2-2.12.02.12.3
Pavlov. Cond. intertrial magazine entries1.62.13.2-1.61.5-1.61.81.5-1.51.3-1.4-1.41.41.4-1.3-1.3-1.3-1.31.71.81.3-1.3-1.31.4-1.11.71.11.8
Pavlov. Cond. lever-magazine prob. diff.5.46.97.22.7-2.72.7-2.5-2.72.7-2.62.72.7-2.7-2.72.72.62.62.6-2.6-2.7-2.62.62.6-2.62.6-2.6-2.6-2.6
Pavlov. Cond. response bias5.27.08.12.7-2.82.7-2.6-2.72.7-2.52.72.7-2.7-2.72.72.62.62.6-2.7-2.8-2.62.62.5-2.62.6-2.7-2.5-2.8
Time in closed arm before self-admin1.92.25.2-0.80.8-1.10.71.3-1.42.3-1.5-1.41.51.5-1.6-1.6-1.7-1.60.91.11.5-1.5-1.61.6-1.91.21.91.5
Time in closed arm after self-admin0.50.51.41.2-0.70.9-0.8-0.60.60.10.60.6-0.5-0.60.50.50.50.6-0.3-0.9-0.90.90.9-0.90.3-0.6-0.3-0.9
Time in open arm before self-admin3.94.36.71.6-1.41.8-1.2-1.92.0-2.52.12.1-2.1-2.12.22.32.32.3-1.2-1.5-2.22.22.5-2.32.5-1.8-2.6-2.1
Time in open arm after self-admin0.30.41.5-0.2-0.40.10.1-0.60.6-1.20.60.6-0.7-0.60.80.80.70.7-0.5-0.2-0.40.40.2-0.31.0-0.5-1.0-0.3
Bone: periosteal estimation2.14.44.72.1-2.12.1-2.1-2.12.1-2.12.12.1-2.1-2.12.12.12.12.1-1.9-2.1-2.22.22.1-2.02.1-2.2-2.1-1.7
Bone: periosteal perimeter2.03.34.32.0-1.91.9-2.0-1.81.8-1.71.81.8-1.8-1.81.71.71.71.7-1.9-2.1-1.81.81.8-1.71.6-2.0-1.6-1.7
Bone: post-yield work1.82.52.91.6-1.61.6-1.6-1.61.6-1.51.61.6-1.6-1.61.61.61.61.6-1.6-1.6-1.71.71.6-1.61.6-1.3-1.6-1.5
Progressive ratio test 1 active lever presses0.40.40.60.7-0.60.7-0.6-0.60.6-0.60.60.6-0.6-0.60.60.60.60.6-0.6-0.3-0.70.70.8-0.80.60.2-0.6-0.7
Progressive ratio test 1 breakpoint0.80.91.21.0-0.91.0-0.8-0.90.9-1.00.90.9-0.9-0.90.90.90.90.9-0.8-0.6-1.11.11.1-1.10.9-0.1-0.9-1.1
Progressive ratio test 1 inactive lever presses0.70.71.11.0-1.00.9-1.0-0.90.9-0.70.80.8-0.8-0.80.80.80.80.8-1.0-1.0-0.80.80.8-0.80.7-1.0-0.7-0.8
Progressive ratio test 2 active lever presses0.10.10.60.7-0.50.5-0.6-0.30.30.20.20.2-0.2-0.20.20.20.10.2-0.8-0.3-0.40.40.3-0.3-0.0-0.10.1-0.4
Progressive ratio test 2 breakpoint0.10.10.50.6-0.40.4-0.4-0.20.20.30.10.1-0.1-0.10.10.10.00.1-0.7-0.1-0.30.30.3-0.3-0.10.10.1-0.3
Progressive ratio test 2 inactive lever presses2.32.75.52.3-2.02.0-2.1-1.61.6-1.01.51.5-1.4-1.41.41.31.31.4-2.3-1.8-1.71.71.6-1.71.0-1.5-0.9-1.7
Incentive Sensitization - Responses0.00.00.30.4-0.10.2-0.20.0-0.00.5-0.1-0.10.10.1-0.1-0.2-0.2-0.1-0.5-0.1-0.20.20.0-0.1-0.3-0.10.4-0.2
Incentive Sensitization - Breakpoint0.00.00.30.2-0.00.1-0.10.1-0.10.5-0.1-0.10.20.2-0.2-0.2-0.2-0.2-0.4-0.0-0.10.1-0.00.0-0.30.10.4-0.1
Sum of active levers in priming session hrs 5-60.20.20.50.3-0.10.4-0.1-0.30.3-0.40.40.3-0.4-0.40.40.40.50.40.10.2-0.70.70.6-0.60.5-0.2-0.5-0.6
Progressive ratio0.10.10.20.1-0.00.10.2-0.10.1-0.00.10.2-0.2-0.20.20.20.30.2-0.2-0.1-0.50.50.5-0.40.3-0.0-0.3-0.3
Food seeking constrained by brief footshock4.15.06.02.2-2.22.3-2.0-2.22.2-2.22.22.2-2.2-2.22.32.22.32.3-2.5-2.1-2.42.42.4-2.42.2-2.0-2.2-2.3
Seeking ratio, punishment vs. effort0.70.91.71.1-1.11.0-1.3-1.01.0-1.00.91.0-0.9-0.90.90.90.80.9-1.1-0.9-0.80.80.7-0.70.7-0.9-0.7-0.8
Retroperitoneal fat weight1.96.27.7-2.82.5-2.72.72.5-2.52.2-2.5-2.52.52.5-2.4-2.4-2.4-2.42.32.52.5-2.5-2.52.5-2.32.52.32.7
Reaction time number correct0.20.30.9-0.90.7-0.70.70.4-0.4-0.2-0.4-0.50.40.4-0.4-0.4-0.3-0.40.60.60.6-0.6-0.60.6-0.20.50.20.6
Reaction time mean minus median0.20.30.60.3-0.50.4-0.3-0.50.5-0.60.60.6-0.6-0.60.60.70.50.6-0.30.0-0.50.50.5-0.40.7-0.2-0.8-0.2
Reaction time mean minus median AUC0.30.40.90.3-0.60.4-0.3-0.60.6-0.70.70.7-0.7-0.70.80.80.70.7-0.20.1-0.50.50.4-0.30.9-0.3-1.0-0.2
Reaction time num false alarms1.41.82.4-1.51.3-1.41.41.3-1.31.4-1.3-1.31.31.3-1.3-1.3-1.3-1.31.31.31.5-1.5-1.31.4-1.21.41.21.6
Reaction time num false alarms AUC1.52.12.7-1.61.5-1.61.61.5-1.51.3-1.4-1.41.41.4-1.4-1.3-1.4-1.41.51.41.4-1.4-1.41.4-1.31.61.21.6
Reaction time trials correct on left0.20.30.9-0.90.7-0.70.70.4-0.4-0.2-0.4-0.50.40.4-0.4-0.4-0.3-0.40.60.60.6-0.6-0.60.6-0.20.50.20.6
Reaction time trials on left0.20.31.0-1.00.7-0.70.80.4-0.4-0.2-0.4-0.50.40.4-0.4-0.4-0.3-0.50.70.60.7-0.7-0.70.7-0.20.50.30.6
Reaction time mean0.00.00.2-0.30.1-0.20.50.1-0.1-0.10.00.0-0.1-0.00.10.10.10.10.30.4-0.10.1-0.00.00.20.5-0.30.1
Reaction time mean AUC0.10.10.6-0.50.3-0.40.80.3-0.3-0.0-0.1-0.10.10.1-0.00.0-0.1-0.00.70.60.1-0.1-0.10.20.10.6-0.20.3
Median of all reaction times0.10.10.5-0.50.3-0.40.70.3-0.30.1-0.2-0.20.20.2-0.1-0.1-0.2-0.10.50.50.1-0.1-0.20.2-0.00.6-0.00.3
Reaction time omissions0.20.31.3-0.80.6-0.70.60.4-0.40.3-0.4-0.40.30.4-0.3-0.3-0.4-0.31.21.20.6-0.6-0.50.6-0.20.80.10.7
Reaction time false alarm rate0.60.91.4-0.80.9-0.91.01.0-1.01.2-1.0-0.90.90.9-0.9-0.9-1.0-0.90.90.80.9-0.9-0.80.8-0.91.10.91.0
Reaction time premature initiation rate0.10.20.30.4-0.50.4-0.6-0.40.4-0.30.40.4-0.4-0.40.40.40.40.4-0.4-0.0-0.50.50.4-0.40.4-0.5-0.3-0.4
Reaction time premature initiations0.00.00.2-0.1-0.1-0.0-0.1-0.20.2-0.40.10.1-0.2-0.20.20.10.20.10.10.4-0.10.1-0.00.00.2-0.2-0.20.0
Std. dev. reaction times0.10.20.60.2-0.40.2-0.1-0.40.4-0.60.50.5-0.6-0.50.60.70.50.6-0.00.1-0.40.40.3-0.30.70.0-0.8-0.2
Reaction time trials completed0.20.31.0-1.00.7-0.70.80.4-0.4-0.2-0.4-0.50.40.4-0.4-0.4-0.3-0.50.70.60.7-0.7-0.70.7-0.20.50.30.6
Reaction time trials AUC0.30.51.3-1.20.9-0.91.00.6-0.6-0.1-0.6-0.60.60.6-0.5-0.5-0.5-0.60.90.70.8-0.8-0.80.8-0.30.60.30.7
Run reversals in cocaine runway, females0.10.10.4-0.2-0.0-0.00.2-0.20.2-0.60.30.3-0.3-0.30.30.40.30.30.10.2-0.00.00.1-0.10.50.6-0.5-0.0
Run reversals in cocaine runway, males0.60.62.0-1.21.2-1.01.20.7-0.70.4-0.6-0.60.50.5-0.5-0.4-0.5-0.51.40.80.6-0.6-0.70.6-0.21.40.10.4
Latency to leave start box in cocaine runway0.00.00.2-0.30.1-0.20.10.0-0.0-0.4-0.0-0.00.00.0-0.0-0.0-0.0-0.00.30.20.1-0.1-0.20.10.10.1-0.1-0.0
Latency to leave start box in cocaine runway, F0.20.20.8-0.80.5-0.60.50.4-0.4-0.3-0.4-0.40.30.3-0.3-0.3-0.3-0.30.90.60.6-0.6-0.60.5-0.20.60.20.5
Latency to leave start box in cocaine runway, M0.00.00.20.2-0.40.2-0.4-0.20.2-0.00.10.1-0.1-0.10.10.00.00.0-0.5-0.2-0.00.0-0.10.0-0.0-0.10.1-0.2
Std. dev. time between licks in bursts1.01.12.61.2-1.11.1-1.5-1.11.1-0.91.01.0-1.0-1.00.90.90.90.9-1.0-1.5-0.90.90.9-1.00.8-1.6-0.8-1.3
Total sessions with >9 infusions1.71.93.0-1.51.4-1.41.61.4-1.41.3-1.4-1.41.41.4-1.3-1.3-1.4-1.31.41.71.3-1.3-1.31.3-1.21.51.21.4
Short access day 1 total inactive lever presses0.60.61.41.1-1.11.0-1.2-0.80.8-0.80.70.7-0.7-0.70.60.60.60.6-1.2-1.0-0.60.60.6-0.60.4-1.1-0.3-0.6
Short access day 10 total inactive lever presses2.52.74.11.7-1.31.7-1.6-1.61.6-1.71.61.6-1.6-1.61.61.51.71.6-1.2-1.8-1.81.81.8-1.81.6-2.0-1.5-1.8
Short access day 1 total infusions0.10.10.4-0.20.2-0.20.10.3-0.30.6-0.4-0.40.40.4-0.4-0.4-0.5-0.40.10.40.4-0.4-0.40.4-0.50.30.50.4
Short access day 10 total infusions0.70.82.3-0.80.9-0.81.10.9-0.90.9-0.9-0.80.80.8-0.8-0.8-0.8-0.80.71.30.6-0.6-0.60.6-0.81.50.70.6
Short access total infusions1.31.52.3-1.11.2-1.21.41.3-1.31.3-1.2-1.21.21.2-1.2-1.2-1.2-1.21.11.51.1-1.1-1.01.0-1.21.41.11.1
Short access day 1 locomotion1.41.53.3-1.81.7-1.61.81.2-1.20.7-1.1-1.11.11.1-1.0-0.9-1.0-1.01.81.51.2-1.2-1.21.2-0.61.00.51.2
Short access day 10 total locomotion0.60.71.20.6-0.50.7-0.4-0.70.7-0.90.80.8-0.8-0.80.90.90.90.9-0.6-0.5-1.11.11.0-1.01.1-0.7-1.1-1.1
Short access total locomotion1.01.12.0-1.21.3-1.11.31.1-1.10.9-1.1-1.11.01.1-1.0-0.9-1.0-1.01.01.40.9-0.9-0.90.9-0.80.80.80.9
One hour access (0.3 mA shock)1.21.42.51.5-1.41.4-1.4-1.21.2-0.81.21.2-1.2-1.21.11.11.11.1-1.6-1.0-1.11.11.3-1.21.0-1.1-1.0-1.1
Compulsive drug intake0.30.31.70.6-0.70.5-1.0-0.50.5-0.20.40.4-0.3-0.40.30.30.20.3-0.8-0.70.1-0.10.2-0.10.1-1.3-0.10.1
One hour access (shock baseline)0.10.10.20.5-0.30.4-0.3-0.20.20.10.20.2-0.2-0.20.20.20.20.2-0.3-0.1-0.40.40.4-0.40.10.1-0.1-0.4
Social response proportion3.43.74.72.1-1.72.0-2.2-1.92.0-2.21.91.9-1.9-1.91.91.91.91.9-1.3-1.6-2.12.12.1-2.01.9-1.9-1.9-1.9
Social responses1.01.33.30.9-0.71.0-0.9-1.11.1-1.81.21.1-1.2-1.21.21.21.31.2-0.3-0.8-1.31.31.3-1.21.4-0.9-1.4-0.9
Social time2.63.54.41.8-1.81.8-1.6-1.91.9-2.11.91.9-2.0-2.02.01.92.02.0-1.6-1.5-2.12.11.9-1.92.0-1.0-2.0-1.7
Soleus weight0.20.63.0-0.80.7-0.80.90.7-0.70.5-0.7-0.60.60.6-0.6-0.6-0.6-0.60.91.20.6-0.6-0.70.8-0.61.70.51.1
Bone: stiffness1.42.32.51.5-1.51.5-1.5-1.51.5-1.51.51.5-1.5-1.51.51.51.51.5-1.5-1.4-1.61.61.6-1.51.5-1.5-1.5-1.5
Tibialis anterior weight0.10.20.3-0.40.2-0.40.30.4-0.40.4-0.4-0.50.50.5-0.5-0.5-0.5-0.50.20.40.6-0.6-0.50.5-0.50.50.50.4
Time to tail flick, vehicle, before self-admin0.80.81.2-0.91.1-0.91.00.9-0.90.9-1.0-1.01.01.0-1.0-0.9-1.0-1.00.70.60.9-0.9-0.80.8-0.9-0.00.90.9
Time to tail flick, vehicle, after self-admin0.40.41.00.9-0.70.8-0.8-0.60.6-0.60.50.5-0.5-0.50.50.40.50.5-1.0-0.8-0.60.60.6-0.60.3-0.5-0.2-0.6
Time to tail flick, test, before self-admin0.90.81.5-0.90.8-0.90.60.8-0.81.1-0.8-0.90.90.9-0.9-0.8-1.0-0.90.70.91.2-1.2-1.11.2-0.90.10.81.2
Time to tail flick, test, after self-admin0.20.20.6-0.70.5-0.50.40.3-0.30.1-0.3-0.30.30.3-0.3-0.2-0.2-0.30.70.30.6-0.6-0.50.6-0.1-0.30.10.8
Delta time to tail flick, vehicle, before/after SA0.80.81.20.9-1.00.9-0.9-1.00.9-1.11.01.0-1.0-1.01.00.90.91.0-0.9-0.6-0.80.80.8-0.80.9-0.3-0.9-0.8
Delta time to tail flick, test, before/after SA0.10.10.2-0.50.3-0.30.40.2-0.2-0.2-0.2-0.20.20.2-0.2-0.2-0.1-0.20.40.30.3-0.3-0.20.3-0.10.20.10.4
Tibia length2.15.97.12.2-2.22.3-2.0-2.42.4-2.52.52.5-2.5-2.52.52.62.52.5-2.0-2.4-2.52.52.6-2.52.6-2.5-2.7-2.3
Ambulatory time before self-admin0.30.30.91.0-0.80.8-0.7-0.40.4-0.20.40.4-0.3-0.30.30.30.30.3-0.9-0.5-0.70.70.7-0.60.1-0.3-0.0-0.5
Ambulatory time after self-admin8.18.911.73.0-3.13.0-2.6-3.03.0-3.43.13.0-3.1-3.13.13.03.13.1-2.6-2.4-2.92.93.1-3.03.1-2.6-3.0-2.8
Bone: tissue strength3.33.24.01.9-2.01.9-1.9-1.91.9-1.71.91.9-1.8-1.81.81.91.71.8-2.0-1.7-1.71.71.7-1.61.7-1.5-1.8-1.6
Total heroin consumption1.01.12.11.5-1.31.3-1.0-1.01.0-0.71.01.0-1.0-1.01.00.91.01.0-1.3-0.4-1.31.31.3-1.20.8-0.7-0.8-1.1
Bone: trabecular number0.91.32.40.8-0.70.9-0.6-1.01.0-1.31.11.1-1.2-1.21.31.31.31.3-0.3-1.0-1.41.41.4-1.31.5-1.1-1.6-1.1
Bone: trabecular spacing0.50.72.01.0-1.21.0-1.2-1.00.9-0.60.80.8-0.8-0.80.80.80.70.7-1.4-0.9-0.60.60.4-0.50.5-0.8-0.5-0.7
Bone: trabecular thickness0.30.41.0-0.80.8-0.80.80.7-0.70.6-0.6-0.60.60.6-0.6-0.6-0.6-0.61.00.60.7-0.7-0.60.6-0.50.40.40.6
Bone: trabecular tissue density2.53.54.0-1.92.0-1.91.91.9-1.91.8-1.9-1.91.91.9-1.9-1.9-1.9-1.91.81.81.9-1.9-1.71.8-1.91.71.91.9
Water consumed over 24 hours0.20.30.50.3-0.30.4-0.3-0.50.5-0.60.50.5-0.5-0.50.60.60.60.5-0.2-0.4-0.50.50.6-0.50.7-0.7-0.7-0.3
Number of responses in last shaping day0.20.21.10.9-0.80.7-1.0-0.40.40.00.30.2-0.2-0.20.10.10.10.1-0.9-0.6-0.30.30.1-0.2-0.2-0.60.2-0.3