Hub : Genes

Kirrel2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression Kirrel2 0.54 0.19 7.5e-05 0.18 0.1 0.17 0.16 4.3e-05 1.8e-03 8.5e-05 1.1e-04
2 Brain gene expression Kirrel2 0.26 0.11 0.0e+00 0.22 0.22 0.22 0.23 2.2e-20 1.6e-20 1.3e-20 2.2e-21
3 Brain alternative TSS NM_001271398.1 0.05 0.03 1.1e-04 0.04 0.04 0.04 0.04 1.4e-04 1.1e-04 6.0e-05 1.9e-04
4 Brain alternative TSS XM_039101535.1 0.05 0.04 1.1e-04 0.04 0.04 0.04 0.04 1.4e-04 1.0e-04 6.6e-05 1.7e-04
5 NAcc gene expression Kirrel2 0.08 0.04 2.7e-07 0.06 0.06 0.06 0.06 9.6e-08 1.5e-07 1.4e-07 3.0e-07
6 PL gene expression Kirrel2 0.08 0.05 3.8e-06 0.05 0.05 0.04 0.05 1.5e-06 4.1e-06 5.3e-05 2.3e-06
7 Brain mRNA stability Kirrel2 0.28 0.11 0.0e+00 0.22 0.23 0.22 0.22 5.4e-20 9.1e-21 2.2e-20 1.1e-20
8 pVTA gene expression Kirrel2 0.49 0.13 6.1e-15 0.29 0.33 0.3 0.33 4.2e-13 6.6e-15 2.6e-13 8.1e-15
9 LHb gene expression Kirrel2 0.28 0.17 1.0e-03 0.17 0.15 0.17 0.15 8.8e-05 2.5e-04 6.6e-05 1.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.62.63.1-1.61.51.7-1.7-1.7-1.8-1.61.6-1.4
Area under the delay curve0.50.51.10.4-0.2-0.50.60.91.00.9-0.90.7
BMI with tail0.20.60.80.3-0.9-0.70.70.90.80.8-0.80.6
BMI without tail0.00.00.1-0.20.20.3-0.3-0.2-0.2-0.20.2-0.0
Body weight1.97.812.3-2.63.53.3-3.2-2.9-2.8-2.82.3-1.1
Weight adjusted by age0.20.30.8-0.90.70.5-0.5-0.5-0.5-0.30.3-0.2
Bone surface0.71.23.0-0.91.71.3-1.3-1.0-1.1-0.90.7-0.6
Bone volume1.22.03.4-1.21.81.6-1.6-1.4-1.5-1.41.1-1.1
Breakpoint value in progressive ratio session0.20.20.40.10.60.00.00.60.60.3-0.60.6
Number of licking bursts4.35.06.22.5-2.0-2.42.42.22.22.2-2.22.0
Context. condit. distance diff. score0.60.71.20.7-0.3-0.70.70.91.00.8-1.01.1
Locomotion velocity, session 10.30.31.4-0.2-0.20.1-0.1-0.6-0.6-0.70.7-1.2
Locomotion distance, session 10.10.10.80.50.90.0-0.00.10.0-0.1-0.20.3
Locomotion velocity, session 20.40.51.21.1-0.9-1.01.00.30.40.4-0.20.0
Locomotion distance, session 22.43.34.31.9-1.5-2.12.11.71.81.7-1.72.0
Locomotion velocity, session 30.30.30.60.7-0.7-0.70.70.30.30.4-0.30.5
Locomotion distance, session 30.60.71.80.70.9-0.40.40.70.70.8-1.01.3
Stereotopy head waving bouts, day 30.70.81.5-0.9-0.60.6-0.6-0.9-0.9-0.91.2-1.1
Stereotopy head waving duration, day 30.40.51.0-0.7-1.00.4-0.4-0.6-0.6-0.61.0-0.9
Locomotion velocity, session 70.30.41.80.50.3-0.40.40.40.50.4-0.71.3
Locomotion distance, session 70.10.10.30.20.40.0-0.0-0.3-0.3-0.30.10.6
Stereotopy head waving bouts, day 72.12.43.41.8-1.2-1.61.61.51.61.5-1.51.6
Stereotopy head waving duration, day 71.51.82.61.2-1.6-1.41.41.41.41.3-1.10.9
Locomotion velocity, session 84.25.06.52.1-2.5-2.62.52.32.32.2-2.11.4
Locomotion distance, session 83.14.55.52.3-1.4-2.22.22.12.22.0-2.22.4
Degree of sensitization distance0.60.60.9-0.5-0.10.5-0.6-0.8-0.9-0.91.0-0.9
Degree of sensitization stereotypy3.33.64.92.2-1.3-1.91.91.92.01.9-1.91.9
Conditioned locomotion0.70.81.20.8-0.9-1.01.01.11.11.0-0.90.3
Cocaine response after cond. corrected0.91.02.3-1.1-0.10.7-0.8-1.1-1.1-0.91.2-1.5
Cocaine response after cond. not corrected2.12.45.4-1.30.21.1-1.2-1.7-1.7-1.51.8-2.3
Cocaine response before conditioning0.91.11.7-0.21.31.0-1.0-1.2-1.2-1.01.0-1.3
Saline control response0.20.30.5-0.40.20.4-0.5-0.7-0.6-0.60.6-0.7
Bone: connectivity density0.30.40.7-0.50.80.7-0.7-0.7-0.8-0.60.6-0.4
Bone: cortical apparent density1.31.72.61.1-1.6-1.51.41.31.31.2-1.21.0
Bone: cortical area1.11.61.8-1.21.31.3-1.3-1.3-1.2-1.21.2-1.4
Bone: cortical porosity4.34.86.52.6-1.7-2.42.42.12.22.3-2.11.7
Bone: cortical porosity5.45.97.82.8-1.9-2.72.72.32.42.5-2.31.9
Bone: cortical thickness0.61.01.4-1.00.60.9-0.9-1.2-1.1-1.11.1-1.1
Bone: cortical thickness0.10.20.5-0.3-0.7-0.10.1-0.1-0.1-0.20.4-0.7
Bone: cortical tissue density1.52.03.01.2-1.7-1.61.61.51.41.3-1.31.0
Condit. Reinf. active minus inactive responses0.10.20.30.1-0.5-0.40.40.60.60.4-0.3-0.1
Condit. Reinf. active-inactive response ratio0.30.40.9-1.0-0.20.5-0.5-0.4-0.4-0.40.7-1.0
Condit. Reinf. active responses1.92.33.11.2-1.8-1.71.71.71.71.5-1.41.0
Condit. Reinf. inactive responses4.14.95.62.2-2.1-2.42.42.22.22.1-2.22.2
Incentive salience index mean0.40.50.70.5-0.6-0.80.80.90.80.8-0.70.2
Condit. Reinf. lever presses0.50.60.90.7-0.4-0.80.90.90.91.0-0.90.4
Condit. Reinf. active minus inactive responses0.40.40.6-0.60.70.7-0.7-0.7-0.7-0.60.6-0.6
Condit. Reinf. active-inactive response ratio0.10.10.3-0.2-0.5-0.20.2-0.00.0-0.00.0-0.5
Condit. Reinf. active responses0.60.82.2-0.31.51.1-1.1-0.9-1.0-0.70.6-0.3
Condit. Reinf. inactive responses0.40.52.80.51.70.6-0.6-0.2-0.30.0-0.20.8
Condit. Reinf. lever presses3.44.67.4-1.62.72.6-2.5-2.2-2.2-2.01.8-1.1
Condit. Reinf. lever reinforcers received0.40.62.3-0.01.50.9-0.9-0.7-0.8-0.50.3-0.0
Conditioned reinforcement - actives0.30.31.41.2-0.3-0.70.70.20.20.3-0.30.3
Conditioned reinforcement - inactives2.83.14.52.0-0.2-1.51.62.01.91.9-2.11.9
Conditioned locomotion3.94.65.92.4-1.9-2.42.42.22.22.1-2.01.6
Patch foraging indifference point 0 sec0.10.10.40.6-0.0-0.20.20.20.20.5-0.30.3
Patch foraging indifference point AUC0.10.10.40.0-0.7-0.30.30.10.10.10.10.2
Delay disc. indifference point, 0s delay1.71.93.20.8-0.3-1.11.11.81.81.4-1.81.5
Delay disc. indifference point, 16s delay0.60.61.00.4-0.1-0.50.60.91.01.0-0.90.8
Delay disc. indifference point, 2s delay0.30.31.00.20.60.00.00.60.70.4-0.81.0
Delay disc. indifference point, 24s delay0.20.20.8-0.30.90.3-0.30.10.10.2-0.30.7
Delay disc. indifference point, 4s delay1.21.31.61.3-0.8-1.11.11.21.21.2-1.10.9
Delay disc. indifference point, 8s delay0.00.00.10.20.1-0.10.10.10.30.3-0.20.3
Indifference point function ln k0.10.20.3-0.20.60.5-0.5-0.4-0.3-0.50.3-0.2
Indifference point function log k0.10.20.3-0.20.60.5-0.5-0.4-0.3-0.50.3-0.2
Patch foraging total patch changes 0 sec0.10.10.40.70.1-0.10.10.20.10.4-0.30.4
Patch foraging total patch changes 12 sec0.00.00.10.3-0.2-0.10.1-0.1-0.10.10.20.2
Patch foraging total patch changes 18 sec0.30.40.80.9-0.1-0.70.70.60.50.7-0.70.6
Patch foraging total patch changes 24 sec0.20.20.80.40.90.2-0.10.20.10.3-0.50.6
Patch foraging total patch changes 6 sec0.00.00.20.4-0.1-0.10.1-0.1-0.20.2-0.00.1
Patch foraging time to switch 0 sec0.10.10.6-0.3-0.8-0.30.3-0.0-0.10.00.2-0.6
Patch foraging water rate 0 sec0.71.21.71.3-1.2-1.11.11.01.11.0-1.01.0
Patch foraging water rate 12 sec0.20.31.71.31.10.2-0.1-0.1-0.00.1-0.30.3
Patch foraging water rate 18 sec0.20.31.21.1-0.4-0.40.40.40.40.4-0.30.5
Patch foraging water rate 24 sec2.53.56.32.3-0.2-1.51.51.92.01.8-2.12.5
Patch foraging water rate 6 sec0.40.61.41.11.0-0.00.00.50.60.6-0.91.2
Seeking ratio, delayed vs. immediate footshock0.40.40.90.60.9-0.20.20.70.70.6-0.80.8
Distance traveled before self-admin0.10.10.10.40.10.0-0.0-0.3-0.4-0.40.3-0.2
Distance traveled after self-admin0.91.03.1-0.21.81.1-1.1-0.9-1.0-0.90.6-0.3
Extensor digitorum longus weight0.51.86.1-2.5-0.21.1-1.1-1.0-0.9-1.31.3-1.7
Bone: elastic displacement0.20.20.5-0.30.10.3-0.4-0.6-0.6-0.70.7-0.3
Bone: elastic work1.31.72.9-1.21.71.5-1.5-1.3-1.3-1.31.2-0.5
Bone: endosteal estimation0.61.33.1-0.91.81.3-1.3-1.1-1.0-1.00.8-1.0
Bone: endosteal perimeter0.30.51.9-0.41.40.9-0.8-0.5-0.4-0.50.3-0.6
Epididymis fat weight0.10.10.50.20.70.2-0.2-0.2-0.0-0.1-0.10.6
Delta time in closed arm before/after self-admin2.52.43.6-1.91.81.8-1.8-1.5-1.3-1.41.2-0.8
Delta time in open arm before/after self-admin0.20.20.60.8-0.6-0.50.40.10.00.5-0.20.0
Diff in mean of infusions in LGA sessions1.71.82.91.1-1.1-1.31.31.61.71.3-1.41.1
Delay discount exponential model param0.30.30.6-0.20.00.3-0.4-0.7-0.8-0.70.7-0.6
Extinction: sum of active levers before priming3.63.64.6-2.12.12.2-2.1-1.7-1.9-1.81.6-1.4
Active lever presses in extinction session 66.46.27.3-2.51.92.4-2.5-2.6-2.6-2.72.6-2.5
Bone: final force0.61.01.9-1.21.41.2-1.2-0.9-0.9-0.80.60.0
Bone: final moment0.91.52.6-1.51.61.4-1.4-1.2-1.1-1.10.9-0.2
Food consumed during 24 hour testing period0.40.41.01.00.6-0.30.30.50.50.6-0.81.0
Glucose0.20.40.7-0.4-0.10.4-0.4-0.8-0.7-0.80.8-0.7
Heart weight0.20.20.50.30.2-0.30.40.60.70.5-0.70.5
Delay discount hyperbolic model param0.40.40.8-0.30.10.4-0.4-0.8-0.9-0.80.8-0.7
Intermittent access intake day 1-15 change1.41.43.1-1.31.81.4-1.4-1.0-1.0-1.00.7-0.6
Intermittent access intake escalation1.01.02.8-1.21.71.3-1.2-0.7-0.7-0.70.5-0.4
Intermittent access intake escalation 21.21.21.8-1.01.31.3-1.2-1.0-1.0-1.00.9-0.8
Intermitt. access day 1 inactive lever presses0.60.71.5-1.21.21.0-1.0-0.6-0.6-0.40.5-0.2
Intermitt. access day 15 inactive lever presses0.60.71.20.2-0.1-0.60.61.01.11.1-1.10.8
Intermitt. access escalation Index0.70.61.00.7-0.3-0.80.80.90.90.8-1.00.8
Intermittent access day 1 total infusions5.76.69.93.1-1.8-2.82.82.62.62.5-2.62.0
Intermittent access day 15 total infusions2.83.14.62.1-0.4-1.61.61.91.91.8-2.11.7
Intermittent access terminal intake (last 3 days)3.74.16.62.6-0.9-1.92.02.12.12.1-2.21.8
Intermittent access total infusions4.24.68.22.9-1.0-2.22.22.22.22.1-2.31.9
Intermittent access day 1 locomotion6.26.58.83.0-1.5-2.72.72.72.72.6-2.72.2
Intermittent access day 15 total locomotion3.03.34.72.2-0.4-1.71.72.02.01.8-2.11.8
Intermittent access total locomotion4.45.07.32.7-1.5-2.42.42.32.32.2-2.21.9
Intermittent access standard deviation0.60.74.0-0.12.00.9-0.8-0.3-0.3-0.3-0.00.2
Left kidney weight4.011.213.6-3.53.63.7-3.7-3.4-3.5-3.33.1-2.3
Right kidney weight5.315.019.2-3.84.44.3-4.3-3.9-4.0-3.83.5-2.3
Cocaine induced anxiety0.50.60.9-1.00.60.9-0.9-0.7-0.8-0.70.7-0.5
Post-drug Anxiety0.10.10.4-0.5-0.60.1-0.1-0.0-0.10.00.3-0.3
Baseline Anxiety1.61.72.41.0-1.5-1.51.51.31.41.4-1.20.9
Tail length3.410.216.3-2.54.03.6-3.6-3.4-3.3-3.12.9-1.8
Length with tail4.416.330.6-3.35.54.7-4.6-4.1-4.0-3.93.3-1.6
Length without tail2.45.311.8-2.03.42.7-2.7-2.2-2.1-2.11.6-0.5
Times rat made contact with spout0.50.61.0-0.40.30.7-0.7-0.9-0.9-1.01.0-0.8
Lifetime Intake2.52.85.12.3-0.9-1.81.81.71.71.6-1.71.3
Liver weight, left0.20.40.7-0.7-0.30.4-0.4-0.7-0.7-0.60.9-0.5
Liver weight, right0.10.20.5-0.0-0.30.1-0.1-0.7-0.6-0.30.70.2
Locomotor activity0.60.91.9-0.4-0.30.6-0.6-1.1-1.3-1.11.4-1.0
Locomotor testing distance0.30.40.90.1-0.20.3-0.3-0.8-0.9-0.80.9-0.9
Locomotor testing rearing0.30.41.11.0-1.0-0.80.80.30.30.3-0.20.2
Locomotion in novel chamber0.10.10.7-0.2-0.8-0.20.20.10.20.00.2-0.1
Locomotion in novel chamber post-restriction0.00.00.1-0.1-0.40.1-0.10.00.0-0.10.1-0.1
Fecal boli incidents, locomotor time 10.91.03.10.4-1.8-1.31.30.90.80.7-0.40.1
Change in fecal boli incidents, locomotor task1.41.32.4-1.40.31.0-1.1-1.1-1.1-1.01.3-1.6
Time >=10cm from walls, locomotor time 10.00.00.1-0.3-0.10.0-0.00.0-0.00.10.1-0.3
Bouts of movement, locomotor time 10.80.91.61.20.3-0.70.71.00.90.8-1.11.3
Total resting periods, locomotor time 10.60.61.11.00.2-0.60.60.90.80.7-0.91.0
Rest time, locomotor task time 10.50.51.90.1-1.4-0.80.80.80.80.5-0.30.1
Distance moved, locomotor task time 10.00.10.30.10.50.2-0.2-0.20.0-0.1-0.1-0.0
Vertical activity count, locomotor time 10.50.52.1-0.11.40.8-0.8-0.7-0.6-0.30.20.1
Time >=10cm from walls, locomotor time 21.51.62.71.0-1.6-1.51.51.31.31.1-0.90.8
Bouts of movement, locomotor time 20.20.20.80.9-0.0-0.30.30.10.10.1-0.20.6
Total resting periods, locomotor time 20.20.20.91.0-0.2-0.40.40.10.10.2-0.20.5
Rest time, locomotor task time 20.30.30.90.5-0.9-0.70.70.50.50.4-0.20.0
Distance moved, locomotor task time 20.20.30.50.6-0.0-0.40.40.40.60.5-0.60.7
Vertical activity count, locomotor time 20.10.20.60.10.80.3-0.3-0.1-0.10.1-0.30.8
Light reinforcement 10.50.92.01.4-0.5-0.90.90.90.71.0-0.91.0
Light reinforcement 21.21.63.70.9-1.9-1.31.31.31.21.3-1.01.0
Bone: marrow area0.71.53.4-0.91.81.4-1.4-1.2-1.1-1.10.9-1.1
Bone: maximum diameter0.81.52.2-1.31.51.3-1.3-1.0-0.9-1.00.9-1.4
Bone: maximum force1.01.73.9-1.42.01.6-1.5-1.2-1.1-1.00.8-0.0
Bone: maximum moment1.22.14.6-1.62.11.7-1.7-1.4-1.3-1.21.0-0.2
Mean time between licks in bursts0.30.40.80.6-0.3-0.50.50.70.70.8-0.70.9
Mean num. licks in bursts4.65.56.2-2.41.92.4-2.4-2.4-2.4-2.52.4-2.1
Cd content in liver0.40.41.0-0.50.60.5-0.5-0.6-0.6-0.70.6-1.0
Co content in liver0.10.10.6-0.2-0.8-0.30.30.30.30.4-0.20.4
Cu content in liver0.20.20.7-0.50.90.6-0.6-0.3-0.3-0.30.2-0.3
Fe content in liver0.10.10.20.2-0.1-0.40.40.40.40.4-0.3-0.5
K content in liver0.10.10.40.6-0.2-0.20.30.30.30.5-0.2-0.3
Mg content in liver0.20.20.90.4-0.9-0.50.40.40.40.5-0.2-0.1
Mn content in liver0.20.21.00.3-1.0-0.30.3-0.1-0.1-0.00.4-0.7
Na content in liver0.20.21.00.51.00.2-0.20.00.00.1-0.2-0.4
Rb content in liver0.81.01.80.2-0.8-0.80.81.31.31.3-1.20.7
Se content in liver2.12.68.20.9-2.9-2.01.91.41.41.4-0.90.6
Sr content in liver0.10.10.50.3-0.7-0.40.4-0.0-0.00.00.2-0.2
Zn content in liver0.10.10.2-0.1-0.4-0.30.30.40.40.5-0.30.0
Bone: minimum diameter0.40.73.3-0.21.80.9-0.9-0.6-0.5-0.40.1-0.3
Time in familiar zone, hab. session 13.33.15.1-2.30.81.9-1.9-1.8-1.7-1.91.8-1.5
Time in novel zone, hab. session 14.84.77.02.6-1.4-2.32.32.12.12.3-2.12.1
Total zone transitions, hab. session 10.40.50.80.9-0.3-0.80.80.80.70.6-0.80.8
Total locomotion distance, hab. session 10.10.20.90.80.90.1-0.0-0.1-0.2-0.10.00.1
Locomotion velocity, hab. session 10.20.20.70.50.80.2-0.2-0.4-0.5-0.30.4-0.5
Time in familiar zone, hab. session 22.52.64.1-1.71.31.8-1.8-1.4-1.4-1.41.5-2.0
Time in novel zone, hab. session 21.01.01.51.2-0.9-1.21.20.80.70.7-0.81.2
Total zone transitions, hab. session 23.03.85.22.3-2.1-2.22.21.81.81.8-1.61.7
Total locomotion distance, hab. session 21.31.73.81.9-0.6-1.31.31.31.21.4-1.31.2
Locomotion velocity, hab. session 21.01.33.01.7-0.6-1.11.21.21.11.2-1.11.0
Novel to familiar place preference ratio0.10.10.50.1-0.1-0.10.10.20.30.3-0.40.7
Novelty place preference0.20.20.60.4-0.1-0.30.30.40.40.4-0.50.7
Time in novel zone, NPP test0.30.40.90.5-0.3-0.50.50.50.60.6-0.71.0
Total zone transitions, NPP test0.00.00.10.3-0.1-0.30.30.10.1-0.1-0.00.3
Total locomotion distance, NPP test1.11.63.6-0.51.91.3-1.2-1.3-1.4-1.31.2-0.6
Locomotion velocity, NPP test1.31.83.5-0.61.91.4-1.4-1.4-1.5-1.41.3-1.0
Intraocular pressure0.30.40.60.3-0.4-0.60.60.70.70.6-0.80.8
Delta distance traveled before/after self-admin1.21.33.7-1.01.91.4-1.4-0.9-0.9-0.80.6-0.3
Delta ambulatory time before/after self-admin1.31.44.8-0.92.21.5-1.4-0.9-0.9-0.80.5-0.4
Parametrial fat weight2.95.78.3-2.90.52.1-2.2-2.7-2.7-2.52.9-2.1
Pavlov. Cond. lever latency0.70.92.3-1.50.81.2-1.2-0.8-0.7-0.90.7-0.6
Pavlov. Cond. magazine entry latency0.50.74.02.0-0.5-0.90.90.20.20.4-0.20.4
Pavlov. Cond. change in total contacts2.72.96.42.5-1.1-1.91.91.51.51.7-1.61.5
Pavlov. Cond. index score0.91.24.32.1-0.9-1.21.20.60.60.9-0.60.6
Pavlov. Cond. latency score0.91.23.81.9-0.7-1.21.20.70.70.9-0.70.7
Pavlov. Cond. lever contacts0.50.51.71.3-0.5-0.90.90.50.50.7-0.50.4
Pavlov. Cond. magazine entry number0.81.14.8-2.20.61.1-1.1-0.5-0.5-0.70.5-0.8
Pavlov. Cond. intertrial magazine entries0.30.41.10.2-1.0-0.60.60.50.50.4-0.40.9
Pavlov. Cond. lever-magazine prob. diff.1.31.65.42.3-1.0-1.41.40.80.81.1-0.80.8
Pavlov. Cond. response bias0.30.32.11.5-0.4-0.60.5-0.1-0.10.10.1-0.0
Pavlov. Cond. lever latency1.41.84.90.9-2.2-1.71.61.21.31.1-0.80.2
Pavlov. Cond. magazine entry latency0.60.72.1-0.41.51.0-0.9-0.7-0.8-0.60.6-0.4
Pavlov. Cond. change in total contacts1.62.27.9-0.92.81.9-1.8-1.1-1.2-1.00.6-0.4
Pavlov. Cond. index score1.31.75.1-0.72.31.5-1.5-1.2-1.2-1.00.8-0.5
Pavlov. Cond. latency score1.11.34.3-0.62.11.4-1.3-1.0-1.1-0.90.7-0.4
Pavlov. Cond. lever contacts1.11.54.9-0.72.21.5-1.5-1.1-1.1-0.90.6-0.2
Pavlov. Cond. magazine entry number1.51.84.70.9-2.2-1.61.61.21.31.2-0.90.6
Pavlov. Cond. intertrial magazine entries0.30.31.20.1-1.1-0.70.60.50.50.5-0.4-0.1
Pavlov. Cond. lever-magazine prob. diff.1.62.05.4-0.92.31.7-1.6-1.3-1.4-1.21.0-0.6
Pavlov. Cond. response bias1.11.55.5-0.62.41.5-1.5-1.0-1.0-0.90.5-0.1
Time in closed arm before self-admin3.33.84.92.0-1.9-2.22.22.01.91.9-1.81.5
Time in closed arm after self-admin0.20.20.5-0.2-0.2-0.30.40.60.50.4-0.50.7
Time in open arm before self-admin4.14.55.4-1.82.32.3-2.3-2.3-2.1-2.12.1-1.6
Time in open arm after self-admin1.21.32.1-0.31.41.2-1.2-1.5-1.3-1.01.1-0.9
Bone: periosteal estimation1.12.33.7-1.41.91.7-1.7-1.5-1.4-1.41.2-1.4
Bone: periosteal perimeter0.91.52.5-1.01.31.2-1.2-1.2-1.1-1.21.1-1.6
Bone: post-yield work0.30.41.60.21.20.2-0.20.30.40.4-0.71.0
Progressive ratio test 1 active lever presses1.21.32.71.60.3-0.91.01.11.11.0-1.31.3
Progressive ratio test 1 breakpoint0.60.61.51.20.6-0.50.60.70.70.6-0.90.9
Progressive ratio test 1 inactive lever presses2.02.23.21.5-0.2-1.31.31.61.61.6-1.81.7
Progressive ratio test 2 active lever presses1.41.53.11.8-0.1-1.21.21.21.21.1-1.31.1
Progressive ratio test 2 breakpoint1.21.33.11.8-0.1-1.21.21.11.11.0-1.21.0
Progressive ratio test 2 inactive lever presses3.94.56.61.8-0.4-1.91.92.52.52.3-2.62.3
Incentive Sensitization - Responses0.40.40.80.9-0.1-0.70.70.70.60.5-0.70.5
Incentive Sensitization - Breakpoint0.30.30.50.7-0.1-0.60.60.60.60.4-0.60.4
Sum of active levers in priming session hrs 5-60.10.10.3-0.50.40.3-0.3-0.1-0.1-0.40.3-0.3
Progressive ratio0.10.10.60.8-0.1-0.50.50.20.20.3-0.20.1
Food seeking constrained by brief footshock0.81.02.8-0.21.71.1-1.1-1.0-1.0-0.90.8-0.8
Seeking ratio, punishment vs. effort0.10.10.4-0.10.60.4-0.3-0.1-0.1-0.1-0.00.1
Retroperitoneal fat weight0.10.52.1-0.4-1.4-0.20.1-0.6-0.6-0.60.8-0.3
Reaction time number correct0.10.10.2-0.20.20.4-0.4-0.3-0.4-0.30.20.1
Reaction time mean minus median0.30.50.6-0.70.80.8-0.7-0.7-0.6-0.60.6-0.3
Reaction time mean minus median AUC1.01.41.9-1.21.41.3-1.3-1.2-1.1-1.01.0-0.8
Reaction time num false alarms0.50.60.80.8-0.9-0.90.90.90.80.8-0.70.2
Reaction time num false alarms AUC0.60.81.10.9-1.0-1.01.01.00.80.9-0.80.2
Reaction time trials correct on left0.10.10.2-0.20.20.4-0.4-0.3-0.4-0.30.20.1
Reaction time trials on left0.10.10.2-0.20.20.4-0.5-0.3-0.4-0.40.3-0.0
Reaction time mean0.10.20.8-0.20.90.3-0.3-0.3-0.3-0.30.3-0.4
Reaction time mean AUC0.10.10.5-0.10.70.3-0.3-0.3-0.2-0.30.3-0.5
Median of all reaction times0.00.10.40.20.6-0.00.0-0.00.0-0.10.0-0.3
Reaction time omissions0.20.30.9-0.50.40.5-0.5-0.6-0.5-0.50.6-1.0
Reaction time false alarm rate0.60.81.10.9-0.9-1.01.01.00.90.9-0.80.1
Reaction time premature initiation rate0.91.22.41.6-0.3-1.01.01.11.11.2-1.21.1
Reaction time premature initiations0.60.91.91.4-0.2-0.70.80.90.81.0-1.11.1
Std. dev. reaction times0.20.41.3-0.51.10.7-0.6-0.5-0.4-0.40.3-0.2
Reaction time trials completed0.10.10.2-0.20.20.4-0.5-0.3-0.4-0.40.3-0.0
Reaction time trials AUC0.20.30.4-0.50.20.6-0.6-0.5-0.7-0.60.5-0.3
Run reversals in cocaine runway, females0.10.10.8-0.30.90.4-0.4-0.00.0-0.1-0.2-0.0
Run reversals in cocaine runway, males3.02.94.5-1.80.21.4-1.4-1.9-2.0-1.72.1-2.0
Latency to leave start box in cocaine runway0.30.30.60.20.5-0.20.30.60.60.5-0.80.7
Latency to leave start box in cocaine runway, F0.50.61.00.3-0.1-0.60.60.90.90.9-1.01.0
Latency to leave start box in cocaine runway, M0.10.10.40.00.60.3-0.3-0.3-0.3-0.40.1-0.4
Std. dev. time between licks in bursts2.53.04.12.0-0.7-1.61.61.71.72.0-1.82.0
Total sessions with >9 infusions0.60.71.51.2-0.9-1.01.00.60.60.7-0.60.4
Short access day 1 total inactive lever presses3.53.95.51.8-0.6-1.81.92.32.22.2-2.32.2
Short access day 10 total inactive lever presses0.10.20.4-0.50.70.2-0.20.30.30.2-0.30.6
Short access day 1 total infusions0.30.40.60.8-0.3-0.70.70.50.50.6-0.60.5
Short access day 10 total infusions0.50.61.01.0-0.6-0.90.90.70.80.7-0.70.5
Short access total infusions0.50.51.21.1-0.8-0.90.90.60.60.5-0.50.3
Short access day 1 locomotion0.30.30.50.4-0.5-0.70.70.50.50.7-0.60.4
Short access day 10 total locomotion1.01.13.01.70.2-0.80.91.01.01.1-1.11.2
Short access total locomotion1.51.52.11.5-1.2-1.41.41.21.21.2-1.10.9
One hour access (0.3 mA shock)1.41.65.32.30.6-0.91.01.11.11.1-1.41.3
Compulsive drug intake0.00.00.10.30.20.2-0.2-0.2-0.2-0.10.2-0.2
One hour access (shock baseline)1.51.73.51.9-0.2-1.21.31.41.31.3-1.41.3
Social response proportion0.40.41.4-1.20.70.9-0.8-0.3-0.2-0.30.20.4
Social responses0.00.10.4-0.7-0.20.2-0.20.1-0.00.10.00.1
Social time0.30.42.3-0.31.50.9-0.8-0.2-0.2-0.2-0.10.2
Soleus weight0.00.10.3-0.6-0.40.0-0.0-0.2-0.1-0.20.3-0.6
Bone: stiffness0.50.81.5-1.11.21.2-1.2-0.7-0.7-0.60.40.0
Tibialis anterior weight0.93.27.0-2.60.51.5-1.5-1.6-1.6-1.91.8-2.2
Time to tail flick, vehicle, before self-admin0.80.81.11.0-1.0-0.90.90.90.90.8-0.80.8
Time to tail flick, vehicle, after self-admin0.10.10.20.4-0.4-0.30.30.1-0.00.10.1-0.2
Time to tail flick, test, before self-admin3.02.94.12.0-0.5-1.51.51.81.71.8-2.01.9
Time to tail flick, test, after self-admin0.10.10.30.5-0.1-0.20.20.30.30.3-0.40.4
Delta time to tail flick, vehicle, before/after SA0.10.10.30.00.50.3-0.3-0.5-0.5-0.30.3-0.5
Delta time to tail flick, test, before/after SA1.21.12.0-0.9-0.20.7-0.7-1.2-1.2-1.11.4-1.4
Tibia length1.64.610.0-2.23.22.6-2.6-2.0-1.8-1.91.5-0.2
Ambulatory time before self-admin0.00.00.30.5-0.2-0.20.20.0-0.1-0.10.0-0.0
Ambulatory time after self-admin1.41.55.7-0.62.41.5-1.5-0.8-1.1-0.90.5-0.1
Bone: tissue strength0.60.62.5-0.61.60.6-0.6-0.1-0.10.1-0.31.5
Total heroin consumption0.20.20.40.40.4-0.20.30.70.60.4-0.60.5
Bone: trabecular number0.81.33.1-1.01.81.4-1.4-1.0-1.1-1.00.8-0.1
Bone: trabecular spacing0.40.51.6-0.10.40.4-0.4-0.8-0.6-0.60.8-1.3
Bone: trabecular thickness0.10.10.3-0.60.20.3-0.3-0.1-0.2-0.30.1-0.2
Bone: trabecular tissue density1.01.34.4-0.9-1.00.3-0.3-1.0-1.0-1.21.4-2.1
Water consumed over 24 hours0.30.30.7-0.40.80.7-0.7-0.5-0.5-0.50.40.1
Number of responses in last shaping day2.42.44.12.0-0.6-1.61.61.51.61.5-1.61.6