Hub : Genes

Kif7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 RMTg gene expression Kif7 0.32 0.18 1.3e-06 0.27 0.2 0.25 0.23 8.3e-08 6.4e-06 2.4e-07 9.4e-07
2 Brain gene expression Kif7 0.17 0.08 5.6e-17 0.15 0.19 0.18 0.18 1.2e-13 2.7e-17 3.6e-16 1.4e-16
3 NAcc gene expression Kif7 0.03 0.02 5.8e-05 0.03 0.04 0.03 0.04 1.3e-04 3.1e-05 1.0e-04 5.3e-05
4 Adipose mRNA stability Kif7 0.08 0.08 4.3e-04 0.02 0.01 0.01 0.01 5.3e-03 6.8e-03 2.5e-02 9.4e-03
5 Adipose isoform ratio XM_008759585.3 0.04 0.03 6.4e-04 0.01 0.02 0 0.01 5.3e-02 3.0e-03 1.7e-01 6.9e-02
6 NAcc intron excision ratio chr1_133640890_133641143 0.02 0.02 2.2e-03 0.02 0.01 0.01 0.01 3.2e-03 9.7e-03 1.4e-02 2.1e-02
7 pVTA gene expression Kif7 0.21 0.11 9.5e-08 0.1 0.12 0.13 0.12 4.6e-05 6.0e-06 3.5e-06 6.5e-06
8 PL gene expression Kif7 0.03 0.03 6.6e-04 0.03 0.03 0.03 0.03 5.8e-04 2.4e-04 5.1e-04 4.7e-04
9 PL mRNA stability Kif7 0.06 0.03 2.8e-07 0.07 0.06 0.05 0.06 7.7e-08 1.5e-07 1.3e-06 2.1e-07
10 Adipose gene expression Kif7 0.36 0.14 0.0e+00 0.18 0.27 0.27 0.28 4.2e-20 2.2e-30 1.9e-29 2.8e-31
11 Adipose isoform ratio XR_005499265.1 0.07 0.04 1.4e-05 0.04 0.04 0.03 0.04 1.6e-05 4.2e-05 6.6e-04 8.1e-05
12 Brain mRNA stability Kif7 0.06 0.05 6.5e-04 0.04 0.03 0.03 0.02 3.0e-04 9.5e-04 1.9e-03 2.4e-03
13 OFC gene expression Kif7 0.34 0.19 9.2e-04 0.08 0.1 0.09 0.09 6.2e-03 2.4e-03 3.6e-03 4.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.72.95.8-2.42.32.2-2.4-2.1-1.6-1.51.61.50.80.3-0.3-0.9
Area under the delay curve0.60.61.40.7-0.8-0.80.40.81.20.6-0.9-0.9-1.10.6-0.5-0.5
BMI with tail1.96.312.93.4-3.1-3.03.62.92.62.8-2.0-2.2-0.6-1.11.01.9
BMI without tail1.32.75.21.2-1.8-1.71.21.72.30.5-2.0-2.1-2.01.4-1.6-1.1
Body weight0.20.72.00.8-0.8-0.90.90.91.31.4-0.8-1.1-0.60.1-0.20.3
Weight adjusted by age0.20.30.5-0.50.70.6-0.4-0.7-0.5-0.30.70.60.5-0.40.40.3
Bone surface2.24.08.3-2.92.52.5-2.9-2.4-1.7-2.41.61.40.60.6-0.7-1.6
Bone volume2.23.88.1-2.82.52.4-2.8-2.4-1.6-2.21.61.40.60.6-0.6-1.5
Breakpoint value in progressive ratio session2.02.24.70.9-1.4-1.30.51.41.10.8-1.9-1.6-1.92.0-2.2-1.5
Number of licking bursts1.01.11.9-0.81.01.1-0.6-1.1-1.4-1.21.31.11.3-1.10.90.4
Context. condit. distance diff. score0.40.51.3-1.00.70.6-1.1-0.6-0.3-0.60.1-0.0-0.30.7-1.0-1.1
Locomotion velocity, session 10.40.41.10.9-0.6-0.61.00.50.30.7-0.1-0.20.2-0.70.80.8
Locomotion distance, session 10.00.00.0-0.00.0-0.0-0.1-0.00.10.20.00.10.0-0.10.20.2
Locomotion velocity, session 20.40.40.90.6-0.7-0.70.50.70.50.5-0.8-0.7-0.90.9-0.5-0.4
Locomotion distance, session 20.10.10.2-0.30.30.3-0.4-0.3-0.5-0.30.30.40.2-0.00.20.0
Locomotion velocity, session 31.21.33.8-1.30.60.7-1.4-0.60.0-1.6-0.2-0.1-1.01.6-1.6-2.0
Locomotion distance, session 32.22.45.7-2.01.11.2-2.1-1.1-0.5-2.20.10.1-1.01.9-1.9-2.4
Stereotopy head waving bouts, day 31.72.03.9-1.72.01.8-1.7-1.8-1.2-0.61.71.61.3-0.70.70.3
Stereotopy head waving duration, day 30.10.20.40.6-0.5-0.40.60.30.4-0.1-0.1-0.10.2-0.50.50.4
Locomotion velocity, session 71.11.23.4-0.4-0.3-0.3-0.70.31.0-0.5-1.0-0.8-1.61.8-1.7-1.6
Locomotion distance, session 70.40.51.4-0.70.20.2-0.7-0.20.2-0.9-0.3-0.3-0.81.0-1.1-1.2
Stereotopy head waving bouts, day 71.41.63.3-1.81.71.6-1.8-1.6-0.8-1.41.21.30.60.3-0.1-0.6
Stereotopy head waving duration, day 70.30.41.0-0.80.50.5-1.0-0.50.3-0.90.10.2-0.30.8-0.6-0.9
Locomotion velocity, session 82.53.04.71.8-2.1-2.11.52.11.81.2-2.1-2.2-1.81.1-1.2-0.6
Locomotion distance, session 80.50.82.0-1.30.80.7-1.4-0.7-0.1-0.60.1-0.1-0.61.0-1.2-1.3
Degree of sensitization distance0.70.71.81.2-0.9-0.91.30.90.60.9-0.4-0.40.1-0.70.60.9
Degree of sensitization stereotypy0.40.41.0-0.90.60.6-1.0-0.60.2-0.60.20.4-0.30.9-0.6-0.8
Conditioned locomotion0.40.51.3-1.11.00.8-1.1-0.7-0.50.00.40.0-0.00.5-0.4-0.5
Cocaine response after cond. corrected0.20.20.70.5-0.1-0.20.40.2-0.30.80.00.20.5-0.50.40.9
Cocaine response after cond. not corrected0.30.30.90.7-0.6-0.70.50.70.31.0-0.6-0.4-0.30.2-0.20.3
Cocaine response before conditioning0.40.51.4-0.4-0.0-0.0-0.50.10.7-0.3-0.5-0.4-1.01.1-1.1-1.2
Saline control response1.72.26.3-0.8-0.3-0.3-0.90.31.7-0.7-1.2-1.3-2.12.3-2.3-2.5
Bone: connectivity density1.93.05.3-2.12.32.2-2.1-2.2-2.0-1.41.91.81.3-0.50.5-0.1
Bone: cortical apparent density1.92.55.12.1-1.9-1.92.01.91.32.3-1.5-1.4-1.10.3-0.10.7
Bone: cortical area3.04.510.7-3.22.62.4-3.3-2.3-1.2-2.01.20.9-0.31.7-1.7-2.5
Bone: cortical porosity0.50.51.5-0.10.30.40.0-0.50.0-0.40.70.71.0-1.21.21.0
Bone: cortical porosity0.30.30.6-0.40.40.5-0.3-0.50.2-0.50.60.60.8-0.80.70.6
Bone: cortical thickness0.81.43.3-1.71.31.2-1.8-1.1-0.7-0.80.40.2-0.41.3-1.3-1.6
Bone: cortical thickness2.32.74.9-0.61.41.3-0.5-1.4-2.20.11.91.92.2-2.02.01.9
Bone: cortical tissue density1.82.35.12.1-1.8-1.92.01.91.12.3-1.4-1.3-0.90.10.10.8
Condit. Reinf. active minus inactive responses0.30.41.0-0.1-0.1-0.2-0.20.30.50.8-0.5-0.5-0.91.0-1.0-0.8
Condit. Reinf. active-inactive response ratio1.21.32.5-1.61.41.4-1.6-1.3-0.9-1.40.90.90.10.6-0.6-1.2
Condit. Reinf. active responses0.40.51.40.2-0.3-0.50.10.50.71.2-0.7-0.6-0.90.9-0.9-0.5
Condit. Reinf. inactive responses0.70.81.90.9-0.9-1.10.81.11.01.4-1.0-1.0-0.70.4-0.40.1
Incentive salience index mean1.72.04.30.3-0.8-1.00.11.11.61.5-1.5-1.5-2.12.0-2.0-1.5
Condit. Reinf. lever presses4.55.910.41.2-2.0-2.20.92.33.02.3-2.9-2.8-3.22.8-2.9-1.9
Condit. Reinf. active minus inactive responses0.50.61.70.6-0.7-0.90.50.81.21.3-0.8-0.9-0.80.3-0.40.1
Condit. Reinf. active-inactive response ratio0.70.72.40.9-0.6-0.81.00.70.71.5-0.3-0.20.2-0.80.81.3
Condit. Reinf. active responses0.81.22.40.2-0.7-0.80.00.81.50.8-1.2-1.3-1.61.3-1.4-1.1
Condit. Reinf. inactive responses2.22.78.4-0.9-0.1-0.1-1.10.21.3-0.8-1.2-1.4-2.32.6-2.7-2.9
Condit. Reinf. lever presses1.82.44.50.5-1.4-1.30.41.31.9-0.3-1.8-1.9-2.11.8-1.9-1.8
Condit. Reinf. lever reinforcers received1.11.53.30.2-0.8-0.90.10.91.70.8-1.4-1.4-1.81.6-1.7-1.3
Conditioned reinforcement - actives0.20.20.7-0.10.10.10.1-0.1-0.3-0.00.40.20.6-0.80.80.6
Conditioned reinforcement - inactives1.31.52.5-1.41.51.4-1.0-1.4-1.6-1.11.41.31.2-0.60.60.2
Conditioned locomotion0.00.00.20.2-0.1-0.1-0.00.1-0.50.0-0.0-0.10.4-0.20.20.2
Patch foraging indifference point 0 sec0.40.62.0-0.3-0.1-0.0-0.40.10.3-0.5-0.5-0.7-1.11.3-1.2-1.4
Patch foraging indifference point AUC1.61.83.2-1.81.81.7-1.8-1.7-1.2-1.51.41.40.8-0.0-0.0-0.4
Delay disc. indifference point, 0s delay0.10.10.3-0.00.40.2-0.2-0.2-0.40.50.40.30.5-0.60.40.5
Delay disc. indifference point, 16s delay0.00.00.10.2-0.1-0.00.0-0.00.3-0.20.10.1-0.2-0.10.30.0
Delay disc. indifference point, 2s delay0.60.71.50.3-0.6-0.6-0.20.61.0-0.1-0.9-0.9-1.21.0-1.0-1.1
Delay disc. indifference point, 24s delay0.20.20.4-0.30.50.5-0.4-0.5-0.3-0.20.60.50.4-0.50.60.3
Delay disc. indifference point, 4s delay1.41.53.50.5-0.9-0.90.21.01.50.4-1.3-1.3-1.91.6-1.5-1.4
Delay disc. indifference point, 8s delay0.80.91.61.1-1.1-1.10.81.11.30.9-1.0-1.0-0.90.3-0.2-0.1
Indifference point function ln k0.60.82.01.3-1.3-1.11.41.10.50.6-0.8-0.8-0.2-0.40.40.6
Indifference point function log k0.60.82.01.3-1.3-1.11.41.10.50.6-0.8-0.8-0.2-0.40.40.6
Patch foraging total patch changes 0 sec0.30.61.9-0.60.20.3-0.6-0.20.1-0.9-0.2-0.4-0.81.2-1.1-1.4
Patch foraging total patch changes 12 sec3.34.27.6-2.62.82.6-2.6-2.6-2.1-2.02.22.21.20.10.1-0.6
Patch foraging total patch changes 18 sec2.12.75.0-2.22.12.1-2.2-2.0-1.7-1.91.51.30.60.4-0.5-1.1
Patch foraging total patch changes 24 sec1.82.36.3-1.50.80.8-1.8-0.7-0.1-1.4-0.3-0.2-1.42.4-2.4-2.5
Patch foraging total patch changes 6 sec1.01.43.9-1.20.70.6-1.3-0.60.4-0.7-0.2-0.3-1.52.0-1.9-2.0
Patch foraging time to switch 0 sec0.50.81.5-1.21.11.1-1.2-1.1-1.0-1.00.80.80.30.4-0.3-0.6
Patch foraging water rate 0 sec0.61.01.61.2-1.3-1.31.11.21.21.1-1.1-1.0-0.6-0.00.00.4
Patch foraging water rate 12 sec7.010.816.43.5-4.0-4.03.34.03.83.1-3.8-3.8-3.01.4-1.6-0.4
Patch foraging water rate 18 sec3.44.67.92.1-2.7-2.61.92.62.81.5-2.6-2.7-2.21.2-1.1-0.5
Patch foraging water rate 24 sec1.72.34.62.1-1.9-1.92.11.81.31.8-1.3-1.3-0.3-0.80.71.1
Patch foraging water rate 6 sec2.94.26.82.3-2.6-2.62.22.62.32.2-2.3-2.4-1.50.4-0.30.4
Seeking ratio, delayed vs. immediate footshock0.81.03.10.00.60.40.3-0.4-0.51.21.00.81.1-1.81.51.5
Distance traveled before self-admin1.51.65.20.2-0.4-0.6-0.10.70.40.7-1.2-1.2-1.82.2-2.3-1.7
Distance traveled after self-admin1.51.73.5-1.71.21.1-1.5-1.1-0.8-1.30.40.4-0.81.7-1.8-1.9
Extensor digitorum longus weight0.41.72.90.9-1.4-1.30.71.41.50.7-1.6-1.7-1.71.4-1.4-1.0
Bone: elastic displacement2.63.09.91.4-0.3-0.51.80.4-0.32.20.70.81.7-2.62.63.2
Bone: elastic work0.30.41.1-0.10.40.30.2-0.3-0.40.70.60.60.8-1.00.91.0
Bone: endosteal estimation3.67.813.2-3.63.53.5-3.3-3.5-2.6-3.42.92.81.9-0.60.5-0.8
Bone: endosteal perimeter2.65.39.6-3.13.02.9-2.9-2.9-2.0-2.42.42.41.5-0.50.4-0.5
Epididymis fat weight1.12.57.92.0-1.5-1.72.01.61.72.8-1.1-1.1-0.2-0.80.51.5
Delta time in closed arm before/after self-admin1.01.03.40.40.30.20.3-0.30.40.60.70.91.1-1.81.71.7
Delta time in open arm before/after self-admin1.21.22.30.6-1.1-1.10.61.20.70.6-1.3-1.5-1.31.3-1.1-1.0
Diff in mean of infusions in LGA sessions1.21.32.7-1.41.01.1-1.5-1.1-0.6-1.60.50.6-0.41.1-1.3-1.5
Delay discount exponential model param0.80.81.8-0.70.90.9-0.4-0.9-1.3-0.61.01.01.4-0.90.70.8
Extinction: sum of active levers before priming0.90.91.40.6-0.9-1.00.41.00.81.2-1.2-1.1-1.01.1-1.0-0.4
Active lever presses in extinction session 61.41.42.71.5-1.5-1.51.51.60.61.6-1.3-1.3-0.70.2-0.30.3
Bone: final force1.32.15.1-2.31.81.7-2.1-1.6-0.9-1.40.80.5-0.21.0-1.0-1.7
Bone: final moment1.11.84.4-2.11.71.6-1.9-1.5-0.9-1.30.80.5-0.10.9-0.9-1.5
Food consumed during 24 hour testing period1.11.33.1-1.81.51.4-1.7-1.4-0.8-1.31.00.80.50.0-0.2-0.6
Glucose0.61.03.01.1-0.5-0.51.20.4-0.30.90.20.30.9-1.41.51.7
Heart weight0.60.81.81.1-0.7-0.81.10.80.51.3-0.3-0.30.4-0.90.91.3
Delay discount hyperbolic model param0.90.92.0-0.70.90.9-0.3-0.9-1.4-0.51.11.11.4-1.00.80.9
Intermittent access intake day 1-15 change0.20.20.4-0.40.40.3-0.5-0.3-0.3-0.40.1-0.0-0.30.6-0.6-0.6
Intermittent access intake escalation0.20.20.5-0.70.60.6-0.5-0.6-0.5-0.50.50.30.1-0.00.0-0.2
Intermittent access intake escalation 20.70.71.1-1.11.00.9-1.0-0.9-0.9-1.00.60.50.00.7-0.7-0.8
Intermitt. access day 1 inactive lever presses1.41.54.11.3-1.0-1.31.61.21.12.0-0.6-0.8-0.1-1.21.21.3
Intermitt. access day 15 inactive lever presses0.10.10.3-0.00.20.1-0.1-0.20.00.20.30.20.3-0.50.50.5
Intermitt. access escalation Index0.00.00.10.2-0.2-0.20.30.20.20.2-0.1-0.2-0.2-0.10.1-0.0
Intermittent access day 1 total infusions0.10.10.4-0.20.20.1-0.3-0.1-0.4-0.2-0.1-0.1-0.10.6-0.6-0.5
Intermittent access day 15 total infusions0.10.10.4-0.10.10.0-0.20.0-0.3-0.0-0.2-0.3-0.30.6-0.6-0.5
Intermittent access terminal intake (last 3 days)0.40.41.0-0.60.50.4-0.6-0.4-0.6-0.60.0-0.0-0.31.0-1.0-0.9
Intermittent access total infusions0.10.10.3-0.20.20.1-0.2-0.1-0.3-0.0-0.1-0.1-0.10.5-0.5-0.4
Intermittent access day 1 locomotion0.10.10.3-0.10.10.0-0.20.0-0.3-0.0-0.1-0.2-0.20.5-0.5-0.4
Intermittent access day 15 total locomotion0.20.20.6-0.1-0.1-0.2-0.30.20.20.1-0.4-0.6-0.70.8-0.8-0.7
Intermittent access total locomotion0.40.40.9-0.90.80.7-0.9-0.7-0.8-0.80.40.40.10.4-0.4-0.6
Intermittent access standard deviation1.92.03.5-1.51.81.8-1.7-1.7-1.9-1.71.41.40.70.2-0.2-0.6
Left kidney weight0.30.92.90.30.20.00.6-0.1-0.01.00.60.41.1-1.61.61.7
Right kidney weight0.10.41.10.5-0.3-0.40.60.30.50.90.1-0.00.4-0.81.01.0
Cocaine induced anxiety0.10.10.5-0.50.50.5-0.7-0.5-0.2-0.50.40.20.1-0.10.1-0.1
Post-drug Anxiety0.40.51.4-0.40.1-0.1-0.50.10.50.1-0.5-0.6-1.01.2-1.2-0.9
Baseline Anxiety1.92.02.91.0-1.4-1.51.11.51.51.4-1.7-1.6-1.61.5-1.5-0.8
Tail length1.54.510.2-2.81.91.8-2.9-1.7-0.5-2.10.40.3-1.32.7-2.8-3.2
Length with tail0.82.86.9-2.52.01.8-2.6-1.7-0.8-1.00.70.6-0.61.8-1.8-1.9
Length without tail0.20.51.3-0.20.60.3-0.1-0.4-0.50.90.70.60.9-0.91.11.1
Times rat made contact with spout0.70.81.91.1-0.9-1.01.01.00.81.4-0.6-0.60.0-0.70.51.0
Lifetime Intake0.10.10.5-0.10.0-0.1-0.10.1-0.10.1-0.3-0.3-0.40.7-0.7-0.5
Liver weight, left1.01.64.11.7-1.2-1.31.81.20.62.0-0.5-0.60.3-1.21.21.6
Liver weight, right0.10.21.90.1-0.0-0.30.10.30.21.4-0.3-0.4-0.40.4-0.3-0.1
Locomotor activity0.30.51.00.6-0.9-0.60.50.61.0-0.5-0.8-0.7-0.80.6-0.5-0.6
Locomotor testing distance1.62.74.51.9-2.1-1.91.71.91.91.0-2.0-1.7-1.61.1-1.1-0.5
Locomotor testing rearing0.81.22.20.6-1.0-0.90.50.91.20.1-1.3-1.1-1.51.4-1.5-1.3
Locomotion in novel chamber0.10.10.40.1-0.1-0.10.10.10.30.1-0.2-0.4-0.60.3-0.4-0.6
Locomotion in novel chamber post-restriction0.10.10.30.5-0.5-0.30.50.3-0.1-0.3-0.2-0.2-0.30.20.1-0.2
Fecal boli incidents, locomotor time 11.51.72.8-1.11.71.5-1.2-1.5-1.7-0.11.61.51.6-0.90.80.8
Change in fecal boli incidents, locomotor task0.30.30.90.6-0.8-0.70.90.60.5-0.0-0.3-0.4-0.0-0.60.50.4
Time >=10cm from walls, locomotor time 13.43.45.11.7-2.1-2.21.72.22.31.6-2.2-2.2-1.91.1-1.3-0.7
Bouts of movement, locomotor time 10.10.10.5-0.40.30.3-0.5-0.20.2-0.00.0-0.0-0.40.3-0.7-0.6
Total resting periods, locomotor time 10.20.20.7-0.50.30.2-0.6-0.20.30.0-0.0-0.1-0.60.5-0.8-0.7
Rest time, locomotor task time 11.31.53.5-1.61.61.5-1.9-1.4-1.1-1.01.11.10.20.4-0.6-0.8
Distance moved, locomotor task time 11.21.32.21.1-1.5-1.51.41.51.30.9-1.4-1.3-0.80.5-0.40.0
Vertical activity count, locomotor time 10.40.40.80.6-0.8-0.70.60.70.4-0.2-0.8-0.9-0.70.7-0.5-0.5
Time >=10cm from walls, locomotor time 20.50.51.9-0.50.20.2-0.5-0.10.3-0.7-0.3-0.1-0.71.1-1.4-1.3
Bouts of movement, locomotor time 24.34.67.4-2.52.62.7-2.3-2.7-2.2-2.42.52.51.7-0.80.8-0.0
Total resting periods, locomotor time 25.76.19.2-2.63.03.0-2.4-3.0-2.6-2.62.92.92.2-1.41.40.4
Rest time, locomotor task time 22.62.94.9-1.21.81.6-1.0-1.7-2.0-0.42.11.92.2-2.21.91.5
Distance moved, locomotor task time 20.60.72.9-0.60.00.0-0.50.00.4-0.6-0.6-0.4-1.01.7-1.5-1.4
Vertical activity count, locomotor time 20.50.52.1-0.0-0.2-0.2-0.20.20.2-0.5-0.6-0.6-1.01.4-1.1-1.2
Light reinforcement 14.68.413.5-3.53.73.6-3.4-3.6-3.4-3.13.23.02.2-0.60.6-0.6
Light reinforcement 22.53.36.1-2.52.42.3-2.4-2.3-1.9-1.61.91.81.00.20.0-0.6
Bone: marrow area3.78.013.3-3.73.53.6-3.3-3.6-2.6-3.53.02.92.0-0.70.6-0.7
Bone: maximum diameter3.46.314.4-3.83.13.1-3.7-3.0-1.6-3.11.91.80.40.9-1.1-2.2
Bone: maximum force1.22.14.8-2.21.81.7-2.1-1.6-0.9-1.60.90.6-0.21.0-1.0-1.7
Bone: maximum moment0.91.63.8-1.91.61.5-1.8-1.4-0.9-1.40.80.5-0.20.8-0.9-1.5
Mean time between licks in bursts1.82.54.1-1.52.01.8-1.3-1.8-1.8-0.61.92.01.8-1.21.10.8
Mean num. licks in bursts2.02.45.71.8-1.7-1.91.61.91.72.4-1.6-1.4-1.00.2-0.20.7
Cd content in liver2.42.65.80.01.00.90.2-1.0-1.70.31.81.62.4-2.32.32.3
Co content in liver1.31.53.81.7-0.9-0.81.90.7-0.21.10.20.20.9-1.61.71.8
Cu content in liver0.40.51.40.3-0.6-0.70.30.71.20.5-0.8-1.0-1.00.6-0.7-0.6
Fe content in liver0.20.20.6-0.50.50.6-0.5-0.6-0.6-0.80.40.50.20.1-0.1-0.4
K content in liver1.81.85.1-1.80.90.9-1.9-0.90.2-1.9-0.0-0.3-0.91.5-1.6-2.3
Mg content in liver0.80.93.6-1.20.50.7-1.2-0.7-0.0-1.90.1-0.0-0.40.8-0.8-1.4
Mn content in liver0.20.30.7-0.60.30.1-0.8-0.10.20.3-0.3-0.3-0.50.9-0.8-0.6
Na content in liver3.13.28.7-2.11.11.2-2.4-1.1-0.2-2.4-0.00.1-1.42.4-2.3-2.9
Rb content in liver0.40.51.31.1-0.9-0.81.20.70.30.1-0.4-0.50.2-0.60.60.6
Se content in liver0.70.82.2-1.51.31.1-1.5-1.1-0.6-0.50.80.70.50.1-0.1-0.2
Sr content in liver0.80.71.7-0.5-0.2-0.2-0.70.20.9-0.5-0.8-0.8-1.21.3-1.3-1.3
Zn content in liver0.40.51.6-0.90.70.9-0.7-0.9-0.5-1.30.80.60.4-0.30.2-0.4
Bone: minimum diameter5.410.017.7-4.24.24.0-3.9-4.0-3.1-3.13.43.22.2-0.70.6-0.7
Time in familiar zone, hab. session 10.30.20.40.5-0.6-0.50.30.50.4-0.0-0.6-0.5-0.50.6-0.4-0.4
Time in novel zone, hab. session 10.50.51.80.00.30.30.4-0.3-0.60.30.70.51.0-1.31.11.1
Total zone transitions, hab. session 11.41.94.8-0.0-0.7-0.7-0.50.81.4-0.2-1.5-1.4-2.02.2-2.1-2.0
Total locomotion distance, hab. session 11.82.55.8-2.22.42.0-2.3-2.0-1.5-0.11.61.50.80.4-0.1-0.4
Locomotion velocity, hab. session 11.62.35.8-2.22.31.9-2.4-1.8-1.30.01.31.30.40.8-0.5-0.7
Time in familiar zone, hab. session 22.52.64.5-0.91.51.5-0.8-1.6-1.9-1.21.91.92.1-1.81.81.3
Time in novel zone, hab. session 21.01.01.70.7-1.0-1.00.61.11.10.7-1.2-1.3-1.31.0-1.1-0.8
Total zone transitions, hab. session 21.11.43.5-0.4-0.4-0.4-0.80.41.2-0.5-1.1-1.1-1.61.7-1.9-1.8
Total locomotion distance, hab. session 23.03.98.5-2.82.92.5-2.7-2.5-2.0-0.72.22.01.4-0.40.2-0.2
Locomotion velocity, hab. session 22.43.37.3-2.72.72.3-2.6-2.3-1.6-0.51.91.71.1-0.10.0-0.3
Novel to familiar place preference ratio0.70.72.3-0.70.20.3-0.9-0.2-0.2-1.1-0.3-0.3-0.61.2-1.3-1.5
Novelty place preference0.50.61.9-0.50.00.1-0.7-0.1-0.1-1.0-0.4-0.4-0.71.1-1.3-1.4
Time in novel zone, NPP test0.50.51.7-0.1-0.3-0.2-0.40.20.2-0.7-0.7-0.6-0.81.1-1.3-1.3
Total zone transitions, NPP test0.20.30.60.2-0.4-0.5-0.00.50.70.4-0.7-0.7-0.70.6-0.7-0.5
Total locomotion distance, NPP test3.04.17.2-1.92.72.3-1.7-2.3-2.40.32.52.42.2-1.41.51.2
Locomotion velocity, NPP test3.24.68.2-2.02.92.5-1.8-2.5-2.60.12.72.62.3-1.41.51.2
Intraocular pressure0.30.41.60.10.10.10.3-0.2-0.10.10.50.50.8-1.30.91.0
Delta distance traveled before/after self-admin2.83.06.9-2.21.92.1-1.7-2.1-1.7-2.61.91.91.2-0.50.5-0.4
Delta ambulatory time before/after self-admin2.12.33.8-1.71.61.7-1.2-1.8-1.4-1.91.81.81.5-1.11.10.4
Parametrial fat weight2.85.48.72.8-2.7-2.82.52.82.62.9-2.5-2.5-2.01.0-0.80.2
Pavlov. Cond. lever latency4.25.413.90.50.60.91.0-1.1-2.5-1.12.22.13.4-3.73.73.2
Pavlov. Cond. magazine entry latency1.51.95.7-0.60.1-0.3-0.80.41.21.1-1.1-1.0-2.02.4-2.3-1.9
Pavlov. Cond. change in total contacts1.21.33.9-1.10.70.4-1.2-0.30.51.1-0.4-0.2-1.42.0-1.9-1.6
Pavlov. Cond. index score3.44.311.9-0.5-0.5-0.8-0.90.92.11.4-1.9-1.8-3.03.5-3.3-2.7
Pavlov. Cond. latency score3.84.813.4-0.6-0.5-0.8-1.00.92.21.3-2.1-2.0-3.23.7-3.5-3.0
Pavlov. Cond. lever contacts3.74.312.1-0.9-0.2-0.5-1.30.62.10.8-1.8-1.7-3.03.5-3.5-3.0
Pavlov. Cond. magazine entry number2.12.76.5-0.10.71.00.2-1.1-1.7-1.51.71.62.4-2.52.41.8
Pavlov. Cond. intertrial magazine entries0.20.20.40.2-0.4-0.40.00.40.60.1-0.6-0.6-0.60.6-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.3.13.910.8-0.4-0.4-0.8-0.80.92.01.5-1.9-1.7-2.93.3-3.2-2.5
Pavlov. Cond. response bias1.31.54.8-0.70.2-0.1-0.90.20.91.0-0.9-0.8-1.72.2-2.1-1.7
Pavlov. Cond. lever latency3.14.18.8-0.51.51.5-0.3-1.6-2.4-0.62.32.63.0-2.62.62.4
Pavlov. Cond. magazine entry latency3.94.56.32.1-2.4-2.52.12.52.42.1-2.5-2.5-2.21.3-1.5-0.7
Pavlov. Cond. change in total contacts3.85.311.00.5-1.6-1.70.31.82.81.1-2.6-2.7-3.33.1-3.0-2.6
Pavlov. Cond. index score4.76.010.71.3-2.2-2.31.22.42.91.4-2.9-3.1-3.32.6-2.8-2.2
Pavlov. Cond. latency score3.84.88.61.1-2.0-2.01.12.12.71.3-2.6-2.7-2.92.3-2.5-2.0
Pavlov. Cond. lever contacts3.54.810.10.4-1.6-1.60.21.62.50.3-2.5-2.7-3.22.9-2.9-2.8
Pavlov. Cond. magazine entry number3.84.66.9-2.02.42.4-1.9-2.5-2.5-1.72.62.62.4-1.51.71.0
Pavlov. Cond. intertrial magazine entries0.50.71.6-1.20.90.9-1.3-0.9-0.4-1.20.50.4-0.10.6-0.5-0.9
Pavlov. Cond. lever-magazine prob. diff.4.25.49.81.1-2.1-2.11.02.22.81.3-2.8-2.9-3.12.6-2.7-2.2
Pavlov. Cond. response bias4.35.811.21.0-2.1-2.10.82.12.80.9-2.9-3.0-3.32.9-3.0-2.6
Time in closed arm before self-admin1.01.12.0-1.31.01.0-1.3-0.9-1.0-1.30.40.4-0.41.2-1.3-1.4
Time in closed arm after self-admin0.60.61.3-0.91.11.0-1.0-1.0-0.6-0.60.91.00.6-0.30.10.1
Time in open arm before self-admin1.01.13.40.9-0.4-0.51.00.40.41.20.20.21.0-1.81.61.8
Time in open arm after self-admin3.13.45.42.1-2.3-2.32.12.31.92.1-2.0-2.1-1.40.5-0.30.2
Bone: periosteal estimation4.18.518.3-4.33.83.7-4.1-3.6-2.4-3.42.62.31.00.6-0.7-2.0
Bone: periosteal perimeter2.54.29.2-3.02.72.6-3.0-2.6-1.6-2.11.91.70.80.3-0.4-1.2
Bone: post-yield work1.01.43.7-1.51.11.2-1.6-1.1-0.5-1.90.50.4-0.31.0-1.0-1.7
Progressive ratio test 1 active lever presses0.00.00.1-0.30.20.10.0-0.1-0.2-0.20.20.10.2-0.20.20.0
Progressive ratio test 1 breakpoint0.00.00.1-0.40.20.2-0.1-0.2-0.2-0.30.10.10.10.0-0.0-0.2
Progressive ratio test 1 inactive lever presses0.80.82.30.8-0.9-1.11.11.11.01.5-1.0-1.1-0.60.1-0.10.3
Progressive ratio test 2 active lever presses0.70.71.3-1.21.11.1-1.0-1.0-1.0-1.10.90.80.5-0.10.1-0.3
Progressive ratio test 2 breakpoint0.60.71.3-1.11.01.0-1.0-1.0-1.0-1.10.70.70.30.3-0.3-0.6
Progressive ratio test 2 inactive lever presses0.10.10.3-0.30.10.0-0.50.00.10.0-0.2-0.3-0.40.5-0.5-0.5
Incentive Sensitization - Responses1.11.12.2-1.41.11.2-1.4-1.1-1.0-1.50.70.70.10.7-0.7-0.9
Incentive Sensitization - Breakpoint1.01.02.0-1.41.11.1-1.3-1.1-1.0-1.40.70.70.10.7-0.7-0.9
Sum of active levers in priming session hrs 5-60.10.10.40.20.00.00.20.0-0.70.20.10.20.4-0.20.20.3
Progressive ratio0.40.51.0-0.80.80.7-1.0-0.7-0.4-0.60.30.4-0.30.7-0.8-0.8
Food seeking constrained by brief footshock1.51.96.5-0.3-0.2-0.3-0.70.40.7-0.2-1.2-1.2-1.92.4-2.6-2.2
Seeking ratio, punishment vs. effort0.40.50.90.4-0.6-0.70.30.70.60.4-0.9-1.0-0.80.8-0.9-0.6
Retroperitoneal fat weight4.314.329.64.5-4.3-4.64.14.64.45.4-3.9-3.9-2.60.7-0.91.0
Reaction time number correct0.40.51.70.20.10.20.2-0.2-0.7-0.10.60.41.1-1.31.31.1
Reaction time mean minus median0.60.82.6-0.2-0.3-0.2-0.20.30.5-0.6-0.7-0.9-1.21.3-1.5-1.6
Reaction time mean minus median AUC0.60.81.60.6-0.9-0.90.60.90.90.3-1.0-1.3-1.10.8-1.0-0.9
Reaction time num false alarms4.96.710.3-2.33.02.9-2.1-2.9-3.2-1.83.13.13.0-2.01.91.2
Reaction time num false alarms AUC4.25.89.5-2.02.72.7-1.9-2.7-3.1-2.02.92.82.9-2.01.81.1
Reaction time trials correct on left0.40.51.70.20.10.20.2-0.2-0.7-0.10.60.41.1-1.31.31.1
Reaction time trials on left0.40.61.90.10.20.20.2-0.3-0.8-0.10.70.51.2-1.41.41.2
Reaction time mean0.20.30.50.6-0.7-0.60.60.60.70.3-0.5-0.6-0.40.0-0.2-0.1
Reaction time mean AUC0.50.71.11.0-1.0-1.01.01.01.00.7-0.8-1.0-0.70.1-0.3-0.1
Median of all reaction times0.10.20.40.7-0.5-0.50.70.50.40.5-0.2-0.30.0-0.40.30.4
Reaction time omissions0.30.40.7-0.50.60.7-0.5-0.7-0.8-0.70.70.70.7-0.40.40.2
Reaction time false alarm rate1.72.43.8-1.31.81.8-1.2-1.8-1.9-1.21.92.01.8-1.11.00.6
Reaction time premature initiation rate1.72.26.7-1.40.60.5-1.8-0.51.1-0.9-0.6-0.3-1.72.6-2.4-2.3
Reaction time premature initiations0.60.82.2-1.00.50.4-1.3-0.40.7-0.6-0.3-0.1-0.81.5-1.3-1.2
Std. dev. reaction times0.81.22.20.4-0.9-0.80.40.91.2-0.2-1.2-1.3-1.51.2-1.4-1.5
Reaction time trials completed0.40.61.90.10.20.20.2-0.3-0.8-0.10.70.51.2-1.41.41.2
Reaction time trials AUC0.50.72.20.20.20.20.2-0.3-0.80.00.70.51.3-1.51.51.3
Run reversals in cocaine runway, females0.80.81.6-1.01.21.1-1.3-1.1-0.8-1.00.80.80.30.4-0.3-0.5
Run reversals in cocaine runway, males2.72.64.21.7-1.9-2.01.62.02.02.1-1.8-1.8-1.20.4-0.60.1
Latency to leave start box in cocaine runway4.04.47.1-2.72.52.5-2.6-2.4-2.2-2.51.61.90.31.5-1.2-1.7
Latency to leave start box in cocaine runway, F4.24.67.5-2.72.62.6-2.6-2.6-2.5-2.71.92.10.90.9-0.8-1.3
Latency to leave start box in cocaine runway, M0.60.51.7-0.80.60.6-0.9-0.5-0.4-0.40.10.3-0.61.3-1.0-1.1
Std. dev. time between licks in bursts1.61.94.0-1.61.61.7-1.5-1.6-1.6-2.01.31.40.8-0.20.0-0.6
Total sessions with >9 infusions0.10.10.3-0.40.40.3-0.4-0.3-0.6-0.30.10.20.10.5-0.5-0.4
Short access day 1 total inactive lever presses0.40.51.80.3-0.5-0.80.40.80.91.3-0.8-1.0-0.70.4-0.40.1
Short access day 10 total inactive lever presses1.11.23.81.1-1.0-1.31.11.21.32.0-0.8-1.0-0.6-0.40.40.8
Short access day 1 total infusions0.70.72.20.1-0.4-0.5-0.10.60.30.5-0.9-0.9-1.11.5-1.5-1.0
Short access day 10 total infusions0.40.51.8-0.20.0-0.0-0.30.1-0.0-0.1-0.5-0.5-0.81.3-1.3-1.1
Short access total infusions0.70.82.9-0.2-0.1-0.1-0.30.20.0-0.1-0.7-0.7-1.11.7-1.7-1.4
Short access day 1 locomotion0.70.81.4-1.21.01.0-1.1-0.9-1.1-0.90.50.5-0.10.8-0.8-0.9
Short access day 10 total locomotion0.91.01.9-1.41.11.2-1.2-1.1-1.1-1.30.80.80.20.4-0.4-0.8
Short access total locomotion1.81.93.5-1.91.51.5-1.6-1.4-1.6-1.80.90.90.11.2-1.2-1.3
One hour access (0.3 mA shock)0.20.20.7-0.40.40.3-0.1-0.3-0.8-0.20.50.30.7-0.70.70.4
Compulsive drug intake0.50.51.70.3-0.3-0.40.70.40.10.90.1-0.10.6-1.31.31.2
One hour access (shock baseline)0.30.40.8-0.70.70.7-0.6-0.7-0.8-0.90.60.50.40.1-0.1-0.3
Social response proportion2.12.24.12.0-1.7-1.62.01.51.41.6-0.7-0.90.2-1.41.51.7
Social responses0.20.20.40.7-0.6-0.50.60.50.50.1-0.3-0.50.0-0.40.50.5
Social time0.70.93.3-0.90.81.0-0.8-1.0-1.0-1.80.90.80.8-0.40.5-0.2
Soleus weight1.95.510.31.0-1.8-2.00.72.12.72.1-2.7-2.9-3.22.8-2.8-2.1
Bone: stiffness1.01.63.6-1.91.41.3-1.9-1.2-0.5-1.20.50.3-0.51.3-1.3-1.8
Tibialis anterior weight1.13.96.41.3-1.9-2.01.12.12.31.6-2.4-2.5-2.42.0-2.0-1.3
Time to tail flick, vehicle, before self-admin0.30.31.20.5-0.5-0.60.50.70.51.1-0.6-0.5-0.40.4-0.40.1
Time to tail flick, vehicle, after self-admin1.31.43.5-1.31.21.3-1.6-1.2-0.7-1.90.60.7-0.31.1-1.0-1.5
Time to tail flick, test, before self-admin2.02.05.2-1.51.11.3-1.6-1.2-1.0-2.30.50.6-0.61.6-1.6-2.0
Time to tail flick, test, after self-admin0.20.20.6-0.20.40.3-0.1-0.4-0.50.00.50.50.8-0.70.60.7
Delta time to tail flick, vehicle, before/after SA1.71.76.9-1.41.01.4-1.5-1.3-1.0-2.60.70.7-0.31.0-0.9-1.7
Delta time to tail flick, test, before/after SA1.00.92.90.20.30.10.3-0.1-0.30.90.60.61.3-1.51.51.7
Tibia length1.23.411.2-2.51.92.2-2.3-2.2-1.3-3.31.51.20.60.3-0.3-1.5
Ambulatory time before self-admin2.62.74.11.2-1.4-1.60.91.71.21.9-1.9-2.0-2.01.8-2.0-1.1
Ambulatory time after self-admin0.80.93.0-0.70.0-0.1-0.30.10.4-0.0-0.6-0.6-1.51.7-1.7-1.6
Bone: tissue strength1.81.82.81.1-1.6-1.41.21.51.40.1-1.7-1.6-1.51.2-1.2-1.0
Total heroin consumption0.70.82.40.2-0.5-0.6-0.00.60.50.6-1.0-0.9-1.01.5-1.6-0.9
Bone: trabecular number2.74.27.3-2.72.72.6-2.7-2.6-2.1-2.12.11.91.2-0.10.2-0.7
Bone: trabecular spacing1.72.24.22.0-2.0-1.92.11.91.51.2-1.4-1.3-0.7-0.20.20.6
Bone: trabecular thickness1.21.43.7-1.81.51.4-1.9-1.3-0.8-0.80.80.7-0.11.0-0.8-1.2
Bone: trabecular tissue density1.11.65.1-0.8-0.00.1-0.90.00.7-0.9-0.8-0.8-1.72.2-1.9-2.3
Water consumed over 24 hours0.30.40.90.6-0.7-0.80.50.80.70.9-0.7-0.8-0.40.0-0.20.2
Number of responses in last shaping day0.10.10.2-0.50.20.2-0.3-0.2-0.5-0.40.10.10.10.2-0.2-0.3