Kif26a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IC intron excision ratio chr6_137069722_137069954 0.86 0.08 4.4e-03 0.01 0.03 0.02 0 1.2e-01 1.8e-02 3.7e-02 2.2e-01
2 PL alternative TSS XM_006240635.5 0.02 0.02 2.2e-03 0.02 0.03 0.02 0.02 3.9e-03 8.4e-04 3.9e-03 4.0e-03
3 PL intron excision ratio chr6_137034083_137036521 0.02 0.02 4.8e-03 0.01 0.01 0.01 0.01 3.0e-02 2.2e-02 3.0e-02 4.7e-02
4 PL alternative TSS XM_006240635.5 0.02 0.02 8.3e-03 0.01 0.02 0.01 0.01 1.1e-02 3.5e-03 1.3e-02 1.2e-02
5 PL alternative TSS NM_001414931.1 0.02 0.02 3.1e-03 0.01 0.02 0.01 0.01 7.6e-03 3.8e-03 1.1e-02 1.3e-02
6 PL alternative TSS NM_001414931.1 0.02 0.02 4.2e-03 0.02 0.01 0.01 0.02 1.8e-03 7.4e-03 3.9e-02 5.0e-03
7 OFC gene expression Kif26a 0.17 0.12 5.5e-04 0.08 0.08 0.06 0.06 5.1e-03 6.5e-03 1.5e-02 1.3e-02
8 Liver gene expression Kif26a 0.03 0.03 2.4e-03 0.02 0.02 0.02 0.02 4.1e-03 5.9e-03 5.0e-03 5.5e-03
9 Liver alternative TSS XM_039112423.2 0.04 0.03 6.6e-04 0.03 0.02 0.02 0.02 3.4e-04 4.1e-03 1.2e-03 1.4e-03
10 PL intron excision ratio chr6_137036208_137036521 0.02 0.01 8.1e-03 0.01 0.01 0.01 0.01 4.7e-02 3.9e-02 3.4e-02 4.7e-02
11 IC intron excision ratio chr6_137069722_137069951 0.85 0.09 6.9e-03 0.01 -0 0.07 0 1.4e-01 3.8e-01 7.9e-04 2.4e-01
12 Brain gene expression Kif26a 0.49 0.24 6.5e-10 0.11 0.12 0.11 0.1 2.9e-10 6.5e-11 4.1e-10 6.3e-10
13 NAcc gene expression Kif26a 0.18 0.1 2.7e-04 0.01 0.02 0.02 0.01 5.9e-03 1.1e-04 3.2e-04 7.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.20.32.01.40.30.30.3-0.30.6-0.5-0.30.50.30.40.4-0.8
Area under the delay curve0.10.10.40.60.30.30.3-0.30.4-0.4-0.30.30.50.20.30.0
BMI with tail3.913.423.34.83.63.63.6-3.53.3-3.5-3.53.83.74.33.1-2.9
BMI without tail1.68.616.73.72.82.82.7-2.72.3-2.7-2.63.22.94.12.3-2.9
Body weight0.31.34.70.3-1.0-1.0-1.01.0-1.11.11.2-0.3-0.92.2-1.4-1.3
Weight adjusted by age0.10.20.5-0.3-0.5-0.5-0.50.5-0.20.60.6-0.3-0.5-0.2-0.7-0.6
Bone surface0.20.31.11.10.30.30.3-0.30.5-0.4-0.20.50.41.00.2-0.9
Bone volume0.20.41.71.30.30.30.3-0.20.4-0.3-0.20.60.41.20.3-1.1
Breakpoint value in progressive ratio session0.10.32.41.60.20.20.2-0.20.0-0.2-0.3-0.2-0.1-0.40.40.7
Number of licking bursts0.10.20.8-0.60.10.10.1-0.10.0-0.3-0.2-0.1-0.1-0.90.40.7
Context. condit. distance diff. score2.83.46.1-2.5-1.9-1.9-1.92.0-1.82.22.2-1.6-1.20.4-2.4-0.1
Locomotion velocity, session 10.20.20.40.1-0.4-0.4-0.40.4-0.40.50.4-0.5-0.3-0.6-0.60.2
Locomotion distance, session 10.81.14.82.20.90.90.9-0.91.0-1.0-1.00.71.00.40.8-0.2
Locomotion velocity, session 20.10.10.70.8-0.0-0.0-0.00.0-0.20.1-0.0-0.20.50.5-0.10.1
Locomotion distance, session 20.50.72.91.70.60.60.6-0.60.7-0.6-0.60.70.71.00.5-0.6
Locomotion velocity, session 30.20.21.10.80.40.40.4-0.40.4-0.4-0.30.31.10.30.3-0.3
Locomotion distance, session 30.00.00.40.0-0.0-0.0-0.00.00.10.00.1-0.10.6-0.1-0.00.1
Stereotopy head waving bouts, day 30.10.10.40.4-0.3-0.3-0.20.2-0.40.00.1-0.4-0.10.10.20.6
Stereotopy head waving duration, day 30.20.30.50.6-0.5-0.5-0.50.5-0.70.30.3-0.6-0.60.5-0.00.6
Locomotion velocity, session 70.30.30.80.10.50.50.5-0.50.7-0.5-0.50.30.9-0.70.40.0
Locomotion distance, session 70.60.72.00.20.90.90.9-0.91.0-0.9-0.80.81.4-0.30.8-0.5
Stereotopy head waving bouts, day 70.60.71.1-0.5-1.0-1.0-1.01.0-0.80.91.0-0.8-1.1-0.0-0.90.2
Stereotopy head waving duration, day 70.30.40.8-0.0-0.7-0.7-0.70.7-0.60.60.7-0.6-0.90.3-0.60.2
Locomotion velocity, session 80.60.81.5-0.7-0.9-0.9-0.90.9-0.71.11.1-0.6-0.40.9-1.2-0.5
Locomotion distance, session 80.40.63.4-0.3-0.3-0.3-0.30.4-0.20.60.60.10.31.8-1.1-1.3
Degree of sensitization distance0.30.32.2-0.30.40.40.4-0.40.4-0.4-0.40.10.2-1.50.50.3
Degree of sensitization stereotypy0.20.20.40.3-0.5-0.5-0.50.5-0.30.50.5-0.4-0.6-0.1-0.50.1
Conditioned locomotion1.11.21.6-1.2-1.2-1.2-1.21.2-1.21.21.2-1.2-1.2-0.2-1.00.7
Cocaine response after cond. corrected0.81.22.31.51.01.01.0-1.10.8-1.2-1.20.81.11.41.30.1
Cocaine response after cond. not corrected2.13.06.22.51.71.71.7-1.71.4-1.8-1.81.51.71.91.9-0.5
Cocaine response before conditioning1.72.12.91.51.51.51.5-1.51.6-1.4-1.31.61.70.81.2-1.5
Saline control response0.10.21.4-0.70.10.10.0-0.00.20.10.20.50.40.3-0.0-1.2
Bone: connectivity density0.20.20.80.1-0.4-0.5-0.50.50.00.50.6-0.0-0.40.3-0.9-0.7
Bone: cortical apparent density5.89.211.7-2.6-3.3-3.3-3.33.2-3.33.03.0-3.4-3.3-2.5-2.52.7
Bone: cortical area0.20.30.9-0.8-0.5-0.5-0.50.5-0.90.30.3-0.7-0.60.10.00.9
Bone: cortical porosity0.50.61.7-0.7-0.6-0.6-0.70.7-0.30.70.9-0.2-0.51.3-1.0-1.0
Bone: cortical porosity0.30.31.7-0.20.10.00.00.00.40.10.20.50.11.3-0.4-1.3
Bone: cortical thickness0.30.51.5-0.8-0.6-0.5-0.50.5-0.90.30.3-0.8-0.7-0.80.21.2
Bone: cortical thickness0.60.81.8-1.3-1.0-1.0-1.01.0-1.00.90.9-0.8-1.0-0.1-0.40.3
Bone: cortical tissue density5.79.011.4-2.5-3.3-3.2-3.23.2-3.23.02.9-3.4-3.3-2.3-2.52.6
Condit. Reinf. active minus inactive responses0.81.01.61.30.90.90.9-0.90.7-1.1-1.00.91.11.11.1-0.3
Condit. Reinf. active-inactive response ratio2.93.16.32.51.81.81.8-1.81.7-1.8-1.81.81.91.61.5-0.8
Condit. Reinf. active responses0.30.30.80.20.50.50.5-0.50.2-0.7-0.60.50.80.70.9-0.1
Condit. Reinf. inactive responses1.41.82.7-1.6-1.4-1.4-1.31.3-1.51.11.2-1.6-1.1-1.4-0.81.2
Incentive salience index mean0.70.91.91.40.90.90.9-0.90.8-1.1-1.00.81.10.71.1-0.3
Condit. Reinf. lever presses0.20.30.70.80.50.50.5-0.50.5-0.6-0.60.40.6-0.00.7-0.0
Condit. Reinf. active minus inactive responses0.60.93.2-1.8-0.9-0.9-0.91.0-0.81.11.2-0.6-0.4-0.3-1.1-0.4
Condit. Reinf. active-inactive response ratio0.50.82.1-1.4-0.9-0.9-0.90.9-0.91.01.1-0.7-0.80.1-1.0-0.1
Condit. Reinf. active responses0.10.10.5-0.3-0.1-0.1-0.20.2-0.10.20.30.20.40.6-0.1-0.7
Condit. Reinf. inactive responses0.60.91.70.80.90.90.9-0.90.9-0.9-0.91.01.31.01.0-0.9
Condit. Reinf. lever presses1.11.64.00.51.21.21.2-1.21.1-0.9-0.91.51.42.00.7-1.7
Condit. Reinf. lever reinforcers received0.20.21.2-0.4-0.2-0.3-0.30.3-0.20.40.40.20.11.1-0.4-1.0
Conditioned reinforcement - actives0.20.71.5-1.1-0.9-0.8-0.80.8-1.20.90.7-0.9-0.7-0.2-0.30.7
Conditioned reinforcement - inactives0.10.31.30.6-0.5-0.5-0.50.5-0.60.50.4-0.4-0.31.2-0.30.1
Conditioned locomotion0.30.51.50.80.60.60.6-0.50.3-0.3-0.50.80.61.20.5-0.9
Patch foraging indifference point 0 sec1.74.86.6-1.5-2.5-2.5-2.52.5-2.62.42.4-2.3-2.3-0.1-1.91.3
Patch foraging indifference point AUC0.71.73.3-0.9-1.4-1.4-1.31.3-1.71.11.2-1.8-1.0-1.0-0.91.8
Delay disc. indifference point, 0s delay0.20.20.7-0.8-0.5-0.5-0.50.5-0.40.40.4-0.5-0.4-0.3-0.20.3
Delay disc. indifference point, 16s delay0.40.65.40.80.40.40.4-0.40.0-0.4-0.40.20.42.30.30.2
Delay disc. indifference point, 2s delay0.50.62.61.00.50.50.6-0.60.7-0.8-0.70.20.6-1.60.80.6
Delay disc. indifference point, 24s delay0.40.74.7-0.40.60.60.6-0.60.7-0.7-0.60.40.9-2.20.80.1
Delay disc. indifference point, 4s delay0.20.20.5-0.1-0.6-0.6-0.60.6-0.20.60.6-0.5-0.4-0.7-0.50.2
Delay disc. indifference point, 8s delay0.10.10.30.60.30.30.3-0.30.4-0.3-0.30.40.40.40.1-0.5
Indifference point function ln k0.51.42.5-1.5-1.2-1.2-1.21.3-0.71.41.4-0.6-1.4-0.4-1.6-0.7
Indifference point function log k0.51.42.5-1.5-1.2-1.2-1.21.3-0.71.41.4-0.6-1.4-0.4-1.6-0.7
Patch foraging total patch changes 0 sec1.95.57.5-1.6-2.7-2.7-2.72.7-2.72.62.6-2.4-2.4-0.1-2.21.3
Patch foraging total patch changes 12 sec2.93.95.8-0.8-2.3-2.2-2.22.2-2.32.02.0-2.4-2.1-0.6-1.71.9
Patch foraging total patch changes 18 sec0.51.22.70.2-1.3-1.3-1.31.2-1.40.81.0-1.6-0.8-0.2-0.41.6
Patch foraging total patch changes 24 sec0.10.20.40.3-0.5-0.5-0.50.5-0.60.30.4-0.5-0.40.1-0.10.4
Patch foraging total patch changes 6 sec1.42.45.4-0.1-1.7-1.7-1.61.6-2.31.41.4-1.8-1.31.3-1.01.7
Patch foraging time to switch 0 sec3.914.826.85.24.04.04.0-3.94.2-3.8-3.74.13.53.03.1-3.0
Patch foraging water rate 0 sec7.026.440.2-6.3-5.4-5.4-5.45.4-5.75.15.1-5.6-4.8-3.9-4.24.0
Patch foraging water rate 12 sec3.413.717.9-3.8-4.1-4.1-4.14.1-4.24.14.0-3.7-3.7-0.5-3.71.8
Patch foraging water rate 18 sec3.06.713.7-3.7-2.7-2.7-2.72.7-2.42.62.5-2.5-2.5-2.2-2.21.4
Patch foraging water rate 24 sec3.85.411.5-3.4-2.5-2.5-2.52.5-2.42.52.4-2.2-2.2-1.4-2.01.1
Patch foraging water rate 6 sec4.76.916.1-4.0-2.7-2.7-2.72.7-2.92.62.5-2.7-2.5-1.6-2.21.6
Seeking ratio, delayed vs. immediate footshock0.40.54.12.0-0.5-0.5-0.50.5-0.30.30.6-0.4-0.40.3-0.6-0.2
Distance traveled before self-admin0.20.50.80.60.70.70.7-0.70.5-0.7-0.80.70.7-0.30.9-0.1
Distance traveled after self-admin0.20.30.40.2-0.6-0.6-0.60.6-0.50.50.6-0.3-0.50.7-0.6-0.4
Extensor digitorum longus weight5.622.227.4-5.0-5.1-5.1-5.15.2-5.25.25.2-4.6-5.1-1.1-5.11.7
Bone: elastic displacement0.40.51.0-1.0-0.7-0.7-0.70.7-0.50.50.7-0.6-0.7-1.0-0.40.4
Bone: elastic work0.10.10.4-0.7-0.3-0.3-0.30.3-0.30.30.3-0.3-0.4-0.2-0.20.3
Bone: endosteal estimation0.30.73.90.50.60.50.5-0.50.5-0.2-0.20.80.62.0-0.1-1.6
Bone: endosteal perimeter0.20.66.10.60.40.40.4-0.4-0.1-0.2-0.30.40.42.50.2-0.4
Epididymis fat weight2.311.428.55.33.33.33.3-3.33.2-3.4-3.43.13.42.83.3-1.5
Delta time in closed arm before/after self-admin0.20.20.7-0.6-0.1-0.1-0.10.1-0.10.40.30.3-0.10.8-0.4-0.7
Delta time in open arm before/after self-admin0.40.51.1-0.8-0.6-0.6-0.60.6-0.60.40.4-0.9-0.9-0.9-0.11.1
Diff in mean of infusions in LGA sessions0.20.32.41.60.10.10.2-0.20.1-0.2-0.3-0.00.00.90.30.5
Delay discount exponential model param0.10.10.3-0.6-0.3-0.3-0.30.3-0.40.30.3-0.3-0.50.2-0.30.1
Extinction: sum of active levers before priming0.40.72.1-0.70.80.80.9-0.90.6-0.9-0.80.50.6-1.50.80.3
Active lever presses in extinction session 62.12.14.9-2.2-1.3-1.4-1.41.4-1.31.51.5-1.2-1.5-1.6-1.50.5
Bone: final force0.20.31.2-1.1-0.4-0.4-0.40.4-0.50.50.5-0.4-0.40.2-0.5-0.1
Bone: final moment0.20.31.3-1.2-0.4-0.4-0.40.4-0.50.50.6-0.4-0.50.1-0.5-0.2
Food consumed during 24 hour testing period0.20.31.10.0-0.5-0.5-0.50.6-0.40.50.6-0.2-0.51.1-0.6-0.5
Glucose0.50.82.71.6-0.9-0.8-0.80.8-0.80.30.3-1.1-0.8-0.60.21.4
Heart weight0.50.81.4-0.4-1.0-1.0-1.01.0-1.21.00.9-1.1-1.00.0-0.80.8
Delay discount hyperbolic model param0.10.10.5-0.7-0.3-0.3-0.30.3-0.50.30.3-0.2-0.50.4-0.2-0.1
Intermittent access intake day 1-15 change0.53.04.51.41.91.91.9-1.91.6-1.8-1.91.82.11.11.8-0.8
Intermittent access intake escalation0.52.94.51.31.91.91.9-1.91.5-1.8-1.91.82.11.01.9-0.6
Intermittent access intake escalation 20.71.22.1-0.11.21.21.3-1.30.8-1.2-1.31.01.3-0.31.50.1
Intermitt. access day 1 inactive lever presses0.10.72.8-1.7-0.8-0.8-0.80.8-0.70.90.8-0.8-0.7-0.4-0.70.5
Intermitt. access day 15 inactive lever presses0.31.62.3-0.3-1.5-1.5-1.51.5-1.51.41.4-1.3-1.40.1-1.10.5
Intermitt. access escalation Index0.30.81.7-0.5-1.1-1.1-1.11.1-0.61.11.2-0.7-0.9-0.1-1.3-0.3
Intermittent access day 1 total infusions0.20.51.31.10.70.70.7-0.70.3-0.5-0.80.60.71.00.8-0.4
Intermittent access day 15 total infusions0.92.13.41.91.51.51.5-1.51.0-1.3-1.61.41.81.51.7-0.6
Intermittent access terminal intake (last 3 days)1.93.39.73.11.71.71.7-1.71.1-1.6-1.91.61.92.12.0-0.7
Intermittent access total infusions1.21.45.22.31.01.01.0-1.00.4-0.8-1.10.91.21.71.2-0.5
Intermittent access day 1 locomotion1.12.13.01.71.51.51.5-1.51.1-1.2-1.51.51.61.41.4-1.0
Intermittent access day 15 total locomotion0.10.51.10.80.70.70.7-0.70.0-0.5-0.80.60.90.91.1-0.0
Intermittent access total locomotion1.11.44.12.01.01.01.0-1.00.4-0.9-1.21.01.21.61.4-0.5
Intermittent access standard deviation0.73.77.62.82.02.01.9-1.91.5-1.7-2.02.01.91.91.9-1.3
Left kidney weight0.75.48.6-0.4-2.6-2.6-2.62.7-2.22.82.8-1.8-2.52.1-2.9-0.6
Right kidney weight0.74.77.5-0.9-2.3-2.3-2.42.4-2.12.62.5-1.7-2.32.2-2.7-0.3
Cocaine induced anxiety2.25.933.0-5.7-1.6-1.6-1.61.6-1.61.71.6-1.9-1.9-3.6-1.32.0
Post-drug Anxiety5.25.921.9-4.7-2.1-2.1-2.02.0-2.12.22.0-2.3-2.3-2.7-1.62.1
Baseline Anxiety0.20.42.81.70.20.20.2-0.20.2-0.3-0.30.20.21.40.3-0.1
Tail length2.613.918.0-4.0-4.1-4.1-4.14.1-4.24.14.2-3.6-4.1-0.7-3.81.2
Length with tail5.323.629.5-4.2-5.4-5.4-5.45.4-5.35.45.4-4.9-5.4-1.1-5.21.9
Length without tail1.68.512.2-1.6-3.3-3.3-3.33.3-2.83.43.3-2.9-3.3-0.9-3.51.2
Times rat made contact with spout0.30.41.5-0.5-0.4-0.4-0.30.3-0.50.20.2-0.8-0.5-1.20.11.1
Lifetime Intake0.81.04.72.20.70.70.7-0.70.1-0.5-0.90.70.91.71.0-0.3
Liver weight, left1.93.35.0-2.2-2.0-2.0-2.02.0-2.21.91.9-1.8-1.9-0.7-1.50.8
Liver weight, right0.30.62.30.70.60.60.6-0.60.5-0.5-0.40.90.71.50.2-1.1
Locomotor activity0.20.30.5-0.2-0.6-0.6-0.60.6-0.40.60.6-0.5-0.1-0.7-0.60.2
Locomotor testing distance0.20.50.8-0.7-0.8-0.8-0.80.8-0.50.70.8-0.7-0.6-0.9-0.80.6
Locomotor testing rearing0.62.13.71.01.61.61.6-1.71.5-1.6-1.61.41.90.01.4-0.0
Locomotion in novel chamber3.95.316.7-4.1-2.2-2.2-2.22.2-2.22.42.2-1.9-2.1-2.0-2.00.5
Locomotion in novel chamber post-restriction0.00.10.6-0.80.20.10.1-0.1-0.1-0.0-0.00.30.20.1-0.0-0.6
Fecal boli incidents, locomotor time 11.02.75.12.31.71.71.7-1.72.0-1.5-1.71.71.70.61.5-0.9
Change in fecal boli incidents, locomotor task1.81.96.3-2.5-1.1-1.1-1.11.2-1.61.41.4-0.4-0.81.0-1.6-1.5
Time >=10cm from walls, locomotor time 10.40.52.60.90.50.50.5-0.50.3-0.3-0.30.70.71.60.2-0.9
Bouts of movement, locomotor time 12.12.710.33.21.41.51.5-1.52.1-1.8-1.61.21.40.21.6-0.4
Total resting periods, locomotor time 12.12.59.03.01.41.41.4-1.42.0-1.7-1.51.21.40.21.5-0.5
Rest time, locomotor task time 10.20.32.40.6-0.0-0.0-0.0-0.00.0-0.4-0.3-0.40.2-1.50.70.9
Distance moved, locomotor task time 10.10.21.2-0.30.30.30.3-0.30.00.1-0.00.4-0.11.1-0.4-0.4
Vertical activity count, locomotor time 10.10.61.40.2-0.8-0.8-0.80.7-0.80.70.8-0.9-1.20.4-0.91.0
Time >=10cm from walls, locomotor time 20.20.62.0-1.4-0.6-0.6-0.60.6-0.20.40.6-0.7-0.8-1.4-0.40.8
Bouts of movement, locomotor time 20.51.72.6-1.4-1.5-1.5-1.51.5-1.21.31.4-1.4-1.6-0.6-1.20.6
Total resting periods, locomotor time 20.31.31.9-1.2-1.3-1.3-1.31.3-1.11.11.2-1.2-1.4-0.2-1.00.5
Rest time, locomotor task time 20.30.43.31.8-0.4-0.4-0.40.4-0.70.30.2-0.60.00.7-0.00.6
Distance moved, locomotor task time 20.10.10.50.20.50.40.5-0.50.7-0.4-0.30.4-0.1-0.30.10.1
Vertical activity count, locomotor time 20.20.51.2-1.0-0.5-0.5-0.50.5-0.20.40.5-0.8-1.0-1.1-0.31.1
Light reinforcement 10.00.00.2-0.5-0.1-0.1-0.10.1-0.00.10.00.0-0.00.2-0.1-0.2
Light reinforcement 21.12.53.71.91.61.71.7-1.71.4-1.6-1.61.51.71.71.4-0.6
Bone: marrow area0.20.63.20.40.50.50.5-0.40.5-0.1-0.20.70.61.8-0.1-1.5
Bone: maximum diameter0.20.41.40.40.50.50.6-0.6-0.0-0.8-0.80.10.50.41.20.7
Bone: maximum force0.10.10.4-0.7-0.2-0.2-0.20.2-0.30.30.3-0.2-0.20.6-0.4-0.3
Bone: maximum moment0.10.10.5-0.7-0.2-0.2-0.20.2-0.20.30.3-0.1-0.20.6-0.4-0.5
Mean time between licks in bursts0.20.93.7-0.00.80.80.8-0.80.6-0.6-0.51.11.41.90.4-1.3
Mean num. licks in bursts0.00.10.10.4-0.3-0.3-0.30.3-0.30.30.3-0.3-0.20.2-0.3-0.1
Cd content in liver0.30.31.3-0.4-0.3-0.3-0.40.4-0.30.50.50.0-0.31.1-0.6-0.8
Co content in liver1.21.52.4-0.9-1.3-1.3-1.31.3-1.31.41.4-1.2-1.20.8-1.50.4
Cu content in liver1.01.22.31.51.11.11.2-1.20.8-1.2-1.20.91.11.11.20.1
Fe content in liver0.40.51.51.20.60.60.6-0.60.6-0.5-0.60.71.10.20.4-0.4
K content in liver0.30.30.6-0.7-0.6-0.6-0.60.6-0.70.60.5-0.7-0.7-0.1-0.40.6
Mg content in liver0.40.51.4-0.6-0.6-0.6-0.60.6-1.10.60.6-0.6-0.61.2-0.40.4
Mn content in liver0.30.32.40.20.10.10.1-0.00.00.20.10.50.21.6-0.3-1.2
Na content in liver0.60.71.61.20.70.70.7-0.80.3-1.0-1.00.20.6-0.11.31.1
Rb content in liver0.91.01.5-0.9-1.1-1.1-1.11.1-1.11.21.2-1.0-0.90.2-1.20.3
Se content in liver0.30.31.70.50.40.40.4-0.40.2-0.3-0.30.60.41.30.2-0.8
Sr content in liver0.20.20.6-0.4-0.4-0.4-0.40.4-0.40.50.4-0.4-0.8-0.1-0.50.1
Zn content in liver1.01.22.2-1.3-1.1-1.1-1.11.1-1.51.01.0-1.1-1.30.9-0.70.8
Bone: minimum diameter0.61.22.3-0.7-1.0-1.0-1.11.1-1.31.21.2-0.8-1.01.5-1.3-0.2
Time in familiar zone, hab. session 10.20.31.20.70.20.20.2-0.20.50.00.00.50.11.1-0.5-1.0
Time in novel zone, hab. session 10.40.41.10.80.50.50.5-0.50.4-0.7-0.60.41.0-0.21.0-0.1
Total zone transitions, hab. session 10.60.83.21.10.50.50.5-0.40.8-0.3-0.21.00.61.8-0.2-1.7
Total locomotion distance, hab. session 10.60.93.7-0.2-0.7-0.7-0.70.8-0.51.01.0-0.1-0.51.9-1.3-1.2
Locomotion velocity, hab. session 10.81.21.9-0.8-1.1-1.1-1.11.2-1.11.31.3-0.7-0.91.3-1.4-0.4
Time in familiar zone, hab. session 20.20.31.4-1.20.40.40.4-0.40.5-0.2-0.20.60.50.0-0.1-0.5
Time in novel zone, hab. session 20.40.53.41.80.30.30.3-0.30.1-0.4-0.40.30.41.00.6-0.3
Total zone transitions, hab. session 20.70.91.30.61.01.01.0-1.01.0-0.9-1.01.11.10.51.0-0.8
Total locomotion distance, hab. session 20.20.30.6-0.6-0.7-0.7-0.70.7-0.80.70.6-0.6-0.30.1-0.20.2
Locomotion velocity, hab. session 20.30.50.8-0.6-0.8-0.8-0.80.8-0.90.80.7-0.8-0.5-0.0-0.20.4
Novel to familiar place preference ratio0.60.71.61.20.80.80.8-0.81.0-0.9-0.90.70.9-0.41.0-0.2
Novelty place preference0.40.51.51.20.60.60.6-0.60.8-0.7-0.70.50.7-0.20.8-0.2
Time in novel zone, NPP test0.30.30.91.00.50.50.5-0.50.8-0.6-0.50.50.7-0.20.6-0.4
Total zone transitions, NPP test0.50.73.31.4-0.0-0.0-0.10.10.40.30.30.50.61.8-0.7-1.7
Total locomotion distance, NPP test0.30.41.60.5-0.4-0.4-0.50.5-0.20.70.6-0.00.21.3-0.7-1.0
Locomotion velocity, NPP test0.30.41.70.7-0.5-0.5-0.50.5-0.30.60.5-0.10.01.3-0.7-0.8
Intraocular pressure0.10.21.6-1.30.0-0.0-0.00.00.4-0.00.20.20.1-1.0-0.2-0.4
Delta distance traveled before/after self-admin0.30.32.40.9-0.1-0.2-0.20.20.10.10.30.1-0.21.5-0.4-0.8
Delta ambulatory time before/after self-admin0.50.81.3-0.2-1.0-1.0-1.01.0-0.70.91.1-0.7-1.10.8-1.1-0.4
Parametrial fat weight0.40.92.11.40.80.80.8-0.70.9-0.8-0.61.10.81.50.4-1.4
Pavlov. Cond. lever latency0.81.01.6-1.2-1.0-1.0-1.01.0-1.11.21.2-0.9-0.80.2-1.30.1
Pavlov. Cond. magazine entry latency0.40.51.2-0.10.80.80.8-0.81.1-0.7-0.70.80.3-1.00.5-0.5
Pavlov. Cond. change in total contacts0.30.30.60.70.60.60.6-0.60.6-0.7-0.70.50.3-0.30.8-0.0
Pavlov. Cond. index score0.91.22.00.91.21.21.2-1.21.4-1.3-1.21.10.8-0.81.2-0.5
Pavlov. Cond. latency score0.70.91.40.81.01.01.0-1.01.2-1.1-1.10.90.6-0.81.1-0.2
Pavlov. Cond. lever contacts1.41.62.41.51.31.31.3-1.41.4-1.6-1.51.11.1-0.51.6-0.1
Pavlov. Cond. magazine entry number0.70.91.6-0.7-1.1-1.0-1.01.0-1.31.01.0-1.1-0.50.3-0.90.8
Pavlov. Cond. intertrial magazine entries5.36.311.2-3.3-2.7-2.7-2.72.7-2.82.62.7-2.5-2.4-0.7-2.41.4
Pavlov. Cond. lever-magazine prob. diff.0.91.11.80.71.11.11.1-1.11.3-1.2-1.20.90.7-1.01.2-0.3
Pavlov. Cond. response bias1.21.62.40.91.41.41.4-1.41.6-1.4-1.41.41.0-0.11.2-1.0
Pavlov. Cond. lever latency1.72.46.4-1.0-1.6-1.5-1.51.5-1.31.31.3-1.8-1.4-2.5-1.01.9
Pavlov. Cond. magazine entry latency3.04.36.21.32.22.22.2-2.22.1-2.0-2.02.51.82.31.8-2.1
Pavlov. Cond. change in total contacts1.74.15.51.42.32.32.3-2.32.1-2.1-2.12.42.01.31.7-1.5
Pavlov. Cond. index score3.04.88.11.62.32.32.2-2.22.1-1.9-1.92.62.02.81.5-2.5
Pavlov. Cond. latency score2.94.76.71.52.32.32.3-2.32.2-2.0-2.02.62.02.51.5-2.3
Pavlov. Cond. lever contacts2.33.48.11.41.91.81.8-1.81.6-1.6-1.62.11.72.81.3-2.1
Pavlov. Cond. magazine entry number2.93.85.6-1.4-2.1-2.0-2.02.0-1.81.81.8-2.3-1.8-2.4-1.62.0
Pavlov. Cond. intertrial magazine entries2.76.07.6-2.2-2.7-2.7-2.72.7-2.72.62.5-2.8-2.2-1.9-2.11.8
Pavlov. Cond. lever-magazine prob. diff.3.45.38.51.72.42.42.4-2.42.2-2.1-2.12.72.22.91.6-2.4
Pavlov. Cond. response bias3.04.110.51.62.01.91.9-1.91.8-1.6-1.62.41.83.21.3-2.6
Time in closed arm before self-admin1.93.34.82.12.02.02.0-2.01.8-2.2-2.11.52.00.12.00.0
Time in closed arm after self-admin0.70.81.00.61.01.01.0-1.01.0-0.9-0.91.01.00.80.8-0.5
Time in open arm before self-admin3.24.07.9-2.8-2.0-2.0-2.02.1-2.22.32.2-1.5-1.9-1.0-2.30.0
Time in open arm after self-admin2.52.75.4-2.3-1.7-1.7-1.71.7-1.61.71.7-1.5-1.8-1.5-1.60.6
Bone: periosteal estimation0.10.22.0-0.1-0.1-0.1-0.10.1-0.40.20.2-0.1-0.11.4-0.1-0.5
Bone: periosteal perimeter0.20.44.40.30.20.20.2-0.2-0.4-0.3-0.30.20.32.10.4-0.1
Bone: post-yield work1.52.55.1-1.9-1.6-1.6-1.61.7-1.31.81.9-1.3-1.6-0.6-2.3-0.0
Progressive ratio test 1 active lever presses0.61.17.52.70.50.50.5-0.50.1-0.4-0.70.40.71.90.8-0.2
Progressive ratio test 1 breakpoint0.81.38.42.90.60.60.6-0.60.2-0.6-0.80.50.82.00.9-0.2
Progressive ratio test 1 inactive lever presses0.61.62.40.2-1.5-1.5-1.51.5-1.41.61.4-1.4-1.20.4-1.20.5
Progressive ratio test 2 active lever presses0.20.21.21.1-0.1-0.1-0.10.0-0.60.3-0.2-0.30.10.70.40.7
Progressive ratio test 2 breakpoint0.20.21.11.1-0.1-0.1-0.10.1-0.70.4-0.1-0.30.00.70.30.6
Progressive ratio test 2 inactive lever presses0.30.81.6-0.6-1.0-1.0-1.00.9-1.31.00.8-1.1-0.8-0.2-0.41.1
Incentive Sensitization - Responses0.00.10.30.2-0.2-0.2-0.20.2-0.50.30.1-0.4-0.1-0.20.10.6
Incentive Sensitization - Breakpoint0.10.10.4-0.1-0.3-0.3-0.30.3-0.60.40.2-0.4-0.2-0.3-0.00.6
Sum of active levers in priming session hrs 5-60.20.21.8-0.3-0.1-0.1-0.10.1-0.40.1-0.0-0.4-0.2-1.30.30.7
Progressive ratio0.10.31.9-1.4-0.3-0.3-0.30.3-1.00.50.3-0.3-0.50.5-0.30.4
Food seeking constrained by brief footshock0.91.12.71.0-1.1-1.1-1.11.1-0.90.80.7-1.4-1.2-0.1-0.51.6
Seeking ratio, punishment vs. effort0.10.22.01.4-0.3-0.3-0.30.30.4-0.00.2-0.4-0.2-0.5-0.10.4
Retroperitoneal fat weight0.31.25.12.10.70.70.7-0.70.6-0.8-0.80.70.82.30.8-0.6
Reaction time number correct1.13.95.2-1.0-2.3-2.3-2.32.3-2.02.22.1-2.1-1.9-1.3-1.71.5
Reaction time mean minus median0.00.10.50.50.20.20.2-0.20.6-0.1-0.20.20.5-0.30.2-0.7
Reaction time mean minus median AUC0.00.21.20.60.10.10.1-0.10.6-0.1-0.10.30.50.4-0.1-1.1
Reaction time num false alarms0.61.01.8-0.5-1.2-1.2-1.21.2-1.41.01.0-1.1-1.10.1-0.60.8
Reaction time num false alarms AUC0.71.52.7-1.0-1.4-1.4-1.41.4-1.61.21.2-1.3-1.2-0.2-0.71.0
Reaction time trials correct on left1.13.95.2-1.0-2.3-2.3-2.32.3-2.02.22.1-2.1-1.9-1.3-1.71.5
Reaction time trials on left1.13.95.3-0.9-2.3-2.3-2.32.3-2.02.32.2-2.1-1.9-1.2-1.81.4
Reaction time mean0.61.23.92.00.90.90.9-0.81.1-0.7-0.81.01.01.60.4-1.3
Reaction time mean AUC0.40.92.81.70.60.60.6-0.60.9-0.4-0.50.80.81.60.1-1.3
Median of all reaction times0.71.15.32.00.60.60.6-0.50.7-0.4-0.40.80.72.30.0-1.2
Reaction time omissions0.50.71.20.8-1.0-1.0-1.11.1-0.40.91.0-0.7-0.50.6-1.0-0.7
Reaction time false alarm rate0.10.10.3-0.5-0.3-0.3-0.30.3-0.60.10.2-0.2-0.30.40.20.2
Reaction time premature initiation rate1.01.54.4-2.1-1.1-1.1-1.11.1-1.41.21.2-1.1-1.1-0.6-1.11.0
Reaction time premature initiations1.33.95.6-2.4-2.1-2.1-2.12.0-2.22.22.1-1.9-1.9-1.2-1.81.5
Std. dev. reaction times0.10.41.10.70.50.50.5-0.50.8-0.4-0.50.60.80.50.3-1.0
Reaction time trials completed1.13.95.3-0.9-2.3-2.3-2.32.3-2.02.32.2-2.1-1.9-1.2-1.81.4
Reaction time trials AUC1.24.25.7-1.1-2.4-2.4-2.42.4-2.12.32.2-2.2-1.9-1.3-1.81.5
Run reversals in cocaine runway, females0.70.83.0-0.40.80.80.8-0.81.3-0.7-0.90.50.8-1.70.9-0.3
Run reversals in cocaine runway, males0.60.62.1-0.7-0.7-0.7-0.70.6-0.80.50.5-1.1-0.6-1.1-0.41.4
Latency to leave start box in cocaine runway0.20.31.1-0.30.50.50.5-0.50.3-0.7-0.70.20.5-0.21.10.4
Latency to leave start box in cocaine runway, F0.40.51.3-0.50.50.50.5-0.60.5-0.8-0.70.00.4-1.11.10.9
Latency to leave start box in cocaine runway, M0.30.32.00.60.30.30.3-0.3-0.1-0.3-0.50.30.41.40.5-0.1
Std. dev. time between licks in bursts0.61.16.80.50.40.30.3-0.20.5-0.00.01.00.62.6-0.4-2.2
Total sessions with >9 infusions0.91.27.02.70.50.50.5-0.50.0-0.4-0.70.50.72.30.7-0.4
Short access day 1 total inactive lever presses0.10.10.80.6-0.2-0.2-0.20.2-0.20.40.2-0.10.00.9-0.2-0.1
Short access day 10 total inactive lever presses0.00.31.51.0-0.2-0.2-0.20.2-0.10.20.30.1-0.01.2-0.5-0.7
Short access day 1 total infusions0.10.30.80.5-0.5-0.4-0.40.4-0.90.60.3-0.5-0.40.8-0.20.5
Short access day 10 total infusions1.62.617.64.20.91.00.9-0.90.5-0.8-1.20.91.32.41.2-0.6
Short access total infusions0.70.96.02.50.50.50.5-0.5-0.0-0.3-0.70.50.61.80.8-0.3
Short access day 1 locomotion0.20.41.50.60.60.60.6-0.60.2-0.4-0.60.50.71.20.6-0.2
Short access day 10 total locomotion1.35.324.54.91.81.81.7-1.71.6-1.8-2.01.82.03.11.9-1.3
Short access total locomotion1.01.69.03.00.60.70.6-0.70.2-0.6-0.90.51.02.51.0-0.2
One hour access (0.3 mA shock)0.10.10.4-0.0-0.1-0.0-0.00.0-0.60.1-0.1-0.20.30.50.40.5
Compulsive drug intake0.20.31.9-1.4-0.2-0.3-0.30.30.10.30.5-0.0-0.2-0.6-0.6-0.2
One hour access (shock baseline)0.00.10.20.1-0.00.00.0-0.0-0.50.2-0.2-0.10.10.40.40.2
Social response proportion0.30.30.60.2-0.6-0.6-0.60.6-0.80.50.6-0.6-0.80.4-0.70.4
Social responses0.10.10.70.80.10.10.1-0.0-0.0-0.1-0.10.10.00.9-0.0-0.3
Social time1.21.83.2-1.3-1.4-1.5-1.51.5-1.31.71.8-0.9-1.00.1-1.8-0.6
Soleus weight0.10.42.70.2-0.2-0.2-0.20.2-0.10.40.40.3-0.11.6-0.7-1.2
Bone: stiffness0.71.22.1-1.5-1.1-1.1-1.11.1-1.31.21.2-1.1-1.10.2-1.30.3
Tibialis anterior weight0.20.71.5-1.2-0.9-0.9-0.90.9-1.10.80.9-0.7-0.90.0-0.90.5
Time to tail flick, vehicle, before self-admin0.20.30.4-0.4-0.6-0.6-0.60.6-0.40.60.6-0.5-0.2-0.4-0.50.1
Time to tail flick, vehicle, after self-admin0.20.40.80.20.70.60.6-0.60.8-0.4-0.60.90.8-0.50.5-0.7
Time to tail flick, test, before self-admin0.20.20.90.90.10.10.1-0.2-0.1-0.4-0.2-0.10.30.90.30.4
Time to tail flick, test, after self-admin0.70.82.0-1.4-0.9-0.9-0.90.9-0.81.00.9-0.8-0.6-0.7-0.70.4
Delta time to tail flick, vehicle, before/after SA0.10.10.30.20.20.20.2-0.20.2-0.1-0.20.20.1-0.50.3-0.0
Delta time to tail flick, test, before/after SA0.81.02.6-1.6-0.9-1.0-1.01.0-0.51.31.1-0.6-0.9-1.0-1.0-0.4
Tibia length0.20.51.5-0.1-0.7-0.7-0.70.6-0.80.30.4-0.9-0.7-0.60.21.2
Ambulatory time before self-admin0.30.81.30.81.01.01.0-1.00.7-1.0-1.10.91.0-0.31.10.1
Ambulatory time after self-admin0.10.10.60.80.20.20.2-0.20.2-0.3-0.20.40.20.60.2-0.6
Bone: tissue strength0.30.31.60.8-0.1-0.1-0.10.1-0.0-0.2-0.1-0.5-0.1-1.30.50.8
Total heroin consumption1.61.93.5-0.6-1.4-1.4-1.31.3-1.61.31.1-1.8-1.3-1.7-0.61.9
Bone: trabecular number0.10.20.50.7-0.3-0.3-0.30.30.10.20.40.0-0.20.4-0.4-0.7
Bone: trabecular spacing0.00.10.3-0.50.20.20.2-0.30.0-0.1-0.30.20.20.10.40.1
Bone: trabecular thickness0.10.11.21.10.20.20.2-0.20.3-0.3-0.20.20.2-0.10.3-0.2
Bone: trabecular tissue density0.30.42.1-0.40.10.10.1-0.2-0.1-0.4-0.4-0.50.0-1.50.81.5
Water consumed over 24 hours1.32.53.7-1.5-1.7-1.7-1.71.7-1.91.51.5-1.9-1.7-0.5-1.01.4
Number of responses in last shaping day0.50.63.31.80.20.20.2-0.20.3-0.1-0.10.50.41.8-0.1-1.1