Kif26a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL alternative TSS XM_006240635.4 0.02 0.02 6.6e-03 0.01 0.01 0.01 0.01 8.9e-03 7.2e-03 1.7e-02 1.2e-02
2 PL intron excision ratio chr6_131212934_131215372 0.02 0.02 7.0e-03 0.01 0.01 0.01 0.01 1.7e-02 1.1e-02 2.0e-02 2.5e-02
3 Liver gene expression Kif26a 0.03 0.03 2.5e-03 0.02 0.01 0.02 0.02 4.8e-03 7.2e-03 5.6e-03 6.7e-03
4 OFC gene expression Kif26a 0.17 0.12 6.0e-04 0.1 0.1 0.1 0.09 2.0e-03 2.7e-03 2.6e-03 3.8e-03
5 Brain gene expression Kif26a 0.4 0.23 3.4e-09 0.1 0.09 0.08 0.1 2.8e-09 1.1e-08 1.3e-07 3.5e-09
6 Liver alternative TSS XM_039112423.1 0.03 0.03 2.5e-03 0.02 0.01 0.02 0.02 1.2e-03 1.3e-02 3.8e-03 5.9e-03
7 NAcc gene expression Kif26a 0.15 0.11 3.7e-03 0.01 0.01 0.01 0.01 9.2e-03 2.6e-02 4.9e-02 1.2e-02
8 PL alternative TSS NM_001414931.1 0.02 0.02 2.7e-03 0.02 0.01 0.01 0.01 5.8e-03 7.9e-03 1.1e-02 1.1e-02
9 PL alternative TSS NM_001414931.1 0.02 0.02 5.0e-03 0.01 0.01 0.01 0.01 1.8e-02 2.8e-02 3.8e-02 3.7e-02
10 pVTA mRNA stability Kif26a 0.17 0.16 8.7e-03 0.03 0.04 0.04 0.03 1.3e-02 7.6e-03 6.0e-03 2.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.00.00.10.20.2-0.2-0.1-0.10.20.30.30.30.1
Area under the delay curve0.10.10.30.20.2-0.3-0.3-0.10.20.20.20.20.5
BMI with tail2.37.48.22.92.9-2.8-2.9-2.62.82.82.82.81.8
BMI without tail0.61.31.71.21.1-1.1-1.2-1.11.31.21.21.2-0.6
Body weight0.41.64.8-1.1-1.21.51.41.6-0.7-0.7-0.7-0.7-2.2
Weight adjusted by age0.20.20.5-0.4-0.40.70.60.7-0.2-0.1-0.1-0.1-0.3
Bone surface0.00.10.10.20.2-0.2-0.2-0.20.20.30.30.30.1
Bone volume0.00.00.10.20.2-0.1-0.1-0.10.20.30.30.3-0.2
Breakpoint value in progressive ratio session0.20.30.70.40.5-0.6-0.6-0.80.1-0.2-0.2-0.20.8
Number of licking bursts0.00.00.10.00.0-0.2-0.2-0.1-0.2-0.1-0.1-0.10.4
Context. condit. distance diff. score2.83.45.1-1.9-1.92.22.22.2-1.5-1.4-1.4-1.4-1.8
Locomotion velocity, session 10.10.20.2-0.4-0.40.50.40.4-0.4-0.4-0.4-0.4-0.2
Locomotion distance, session 10.60.71.10.90.9-0.9-0.9-0.80.70.80.80.81.1
Locomotion velocity, session 20.00.00.0-0.1-0.1-0.00.00.1-0.2-0.1-0.1-0.1-0.1
Locomotion distance, session 20.30.40.50.60.6-0.6-0.6-0.50.60.70.70.70.3
Locomotion velocity, session 30.10.10.20.40.4-0.4-0.3-0.30.30.40.40.40.4
Locomotion distance, session 30.00.00.0-0.1-0.10.10.10.1-0.1-0.1-0.1-0.10.1
Stereotopy head waving bouts, day 30.10.10.2-0.3-0.30.10.20.1-0.3-0.4-0.4-0.4-0.2
Stereotopy head waving duration, day 30.20.20.3-0.5-0.40.30.30.3-0.4-0.5-0.5-0.5-0.5
Locomotion velocity, session 70.20.20.70.50.5-0.5-0.4-0.40.30.40.40.40.8
Locomotion distance, session 70.60.80.91.00.9-0.9-0.8-0.80.91.01.01.00.8
Stereotopy head waving bouts, day 71.21.31.5-1.2-1.21.21.21.2-1.0-1.1-1.1-1.1-1.2
Stereotopy head waving duration, day 70.40.50.5-0.7-0.70.70.70.7-0.6-0.7-0.7-0.7-0.6
Locomotion velocity, session 80.60.71.2-0.8-0.91.11.01.1-0.5-0.5-0.5-0.5-1.0
Locomotion distance, session 80.20.30.7-0.2-0.30.70.70.80.10.20.20.2-0.7
Degree of sensitization distance0.20.20.30.40.4-0.5-0.4-0.50.20.30.30.30.6
Degree of sensitization stereotypy0.20.20.3-0.5-0.50.50.50.6-0.4-0.5-0.5-0.5-0.5
Conditioned locomotion1.21.41.7-1.3-1.31.21.21.2-1.2-1.2-1.2-1.2-0.8
Cocaine response after cond. corrected1.11.21.51.01.0-1.2-1.2-1.10.91.21.21.20.9
Cocaine response after cond. not corrected2.22.43.11.61.6-1.8-1.8-1.71.51.41.41.41.3
Cocaine response before conditioning1.21.42.71.51.5-1.3-1.4-1.41.60.50.50.50.9
Saline control response0.10.20.40.30.20.0-0.1-0.10.6-0.6-0.6-0.6-0.3
Bone: connectivity density0.20.30.6-0.5-0.50.70.70.7-0.3-0.2-0.2-0.2-0.6
Bone: cortical apparent density7.59.912.1-3.3-3.22.92.92.9-3.5-3.5-3.5-3.5-2.0
Bone: cortical area0.40.61.1-0.8-0.80.40.40.5-1.1-1.0-1.0-1.0-0.1
Bone: cortical porosity0.20.20.7-0.4-0.40.70.70.70.0-0.0-0.0-0.0-0.8
Bone: cortical porosity0.10.10.30.20.10.20.20.20.60.50.50.5-0.4
Bone: cortical thickness0.40.61.2-0.8-0.70.30.30.4-1.1-1.1-1.1-1.10.1
Bone: cortical thickness0.70.81.4-0.9-0.90.80.80.9-0.7-0.8-0.8-0.8-1.2
Bone: cortical tissue density7.710.112.3-3.3-3.33.02.92.9-3.5-3.5-3.5-3.5-2.1
Condit. Reinf. active minus inactive responses0.70.80.90.90.9-1.0-0.9-0.90.90.80.80.80.8
Condit. Reinf. active-inactive response ratio2.83.03.21.81.8-1.8-1.7-1.61.81.71.71.71.8
Condit. Reinf. active responses0.20.20.40.50.5-0.6-0.5-0.50.50.40.40.40.2
Condit. Reinf. inactive responses1.61.92.7-1.4-1.41.11.21.2-1.6-1.5-1.5-1.5-1.4
Incentive salience index mean0.60.71.00.90.9-1.0-0.9-0.90.80.80.80.80.8
Condit. Reinf. lever presses0.10.20.30.40.4-0.6-0.5-0.50.30.30.30.30.5
Condit. Reinf. active minus inactive responses0.60.81.5-1.0-1.01.21.21.0-0.9-0.2-0.2-0.2-1.1
Condit. Reinf. active-inactive response ratio0.70.81.1-0.9-0.91.11.10.9-0.80.70.70.7-1.0
Condit. Reinf. active responses0.10.10.4-0.2-0.30.40.40.3-0.2-0.1-0.1-0.1-0.7
Condit. Reinf. inactive responses0.40.50.70.80.8-0.8-0.7-0.80.8-0.6-0.6-0.60.2
Condit. Reinf. lever presses0.60.82.01.21.1-0.8-0.8-0.91.40.60.60.60.3
Condit. Reinf. lever reinforcers received0.10.20.8-0.3-0.30.60.60.5-0.2-0.1-0.1-0.1-0.9
Conditioned reinforcement - actives2.22.22.5-1.5-1.51.41.41.4-1.5-1.6-1.6-1.6-1.3
Conditioned reinforcement - inactives0.50.60.7-0.7-0.70.60.60.8-0.6-0.8-0.8-0.8-0.8
Conditioned locomotion0.30.30.90.70.7-0.6-0.6-0.50.90.30.30.3-0.0
Patch foraging indifference point 0 sec3.75.96.6-2.6-2.62.32.42.4-2.5-2.6-2.6-2.6-1.9
Patch foraging indifference point AUC2.02.33.3-1.6-1.51.31.21.2-1.7-1.8-1.8-1.8-0.4
Delay disc. indifference point, 0s delay0.20.20.4-0.5-0.50.50.50.6-0.3-0.3-0.3-0.3-0.5
Delay disc. indifference point, 16s delay0.10.10.50.20.2-0.2-0.3-0.20.20.10.10.10.7
Delay disc. indifference point, 2s delay0.30.41.40.50.5-0.7-0.7-0.60.30.30.30.31.2
Delay disc. indifference point, 24s delay0.30.31.20.40.4-0.5-0.5-0.40.30.30.30.31.1
Delay disc. indifference point, 4s delay0.20.30.4-0.5-0.50.50.50.6-0.4-0.4-0.4-0.4-0.7
Delay disc. indifference point, 8s delay0.10.10.10.20.2-0.2-0.20.10.40.40.40.40.2
Indifference point function ln k1.11.64.4-1.2-1.21.41.41.5-0.7-0.8-0.8-0.8-2.1
Indifference point function log k1.11.64.4-1.2-1.21.41.41.5-0.7-0.8-0.8-0.8-2.1
Patch foraging total patch changes 0 sec4.26.97.6-2.8-2.82.52.62.6-2.6-2.7-2.7-2.7-2.2
Patch foraging total patch changes 12 sec3.74.85.9-2.3-2.32.02.02.3-2.4-2.4-2.4-2.4-1.0
Patch foraging total patch changes 18 sec1.41.82.8-1.4-1.41.00.81.1-1.7-1.6-1.6-1.6-0.1
Patch foraging total patch changes 24 sec0.20.30.4-0.6-0.60.40.40.4-0.5-0.6-0.6-0.6-0.2
Patch foraging total patch changes 6 sec1.82.73.7-1.7-1.71.41.41.5-1.9-1.9-1.9-1.9-0.7
Patch foraging time to switch 0 sec10.015.517.74.14.1-3.8-3.9-3.64.04.24.24.23.0
Patch foraging water rate 0 sec17.628.232.3-5.6-5.55.15.14.8-5.5-5.7-5.7-5.7-4.3
Patch foraging water rate 12 sec10.015.316.8-4.1-4.13.94.14.0-3.5-3.8-3.8-3.8-4.0
Patch foraging water rate 18 sec5.06.87.5-2.7-2.72.52.72.6-2.4-2.6-2.6-2.6-2.5
Patch foraging water rate 24 sec4.15.76.6-2.5-2.52.42.52.3-2.1-2.3-2.3-2.3-2.6
Patch foraging water rate 6 sec4.76.87.5-2.7-2.72.52.62.5-2.5-2.7-2.7-2.7-2.5
Seeking ratio, delayed vs. immediate footshock0.20.30.7-0.6-0.60.60.40.8-0.4-0.4-0.4-0.4-0.3
Distance traveled before self-admin0.50.52.30.40.5-0.8-0.8-1.10.20.00.00.01.5
Distance traveled after self-admin0.40.50.6-0.8-0.80.70.70.7-0.7-0.6-0.6-0.6-0.7
Extensor digitorum longus weight6.425.429.3-5.2-5.35.45.35.4-4.8-4.7-4.7-4.7-4.7
Bone: elastic displacement0.50.60.7-0.8-0.80.70.70.7-0.8-0.8-0.8-0.8-0.7
Bone: elastic work0.00.10.1-0.3-0.30.20.20.2-0.3-0.3-0.3-0.3-0.1
Bone: endosteal estimation0.10.30.60.40.4-0.1-0.1-0.20.80.80.80.8-0.3
Bone: endosteal perimeter0.00.00.10.20.2-0.1-0.2-0.20.20.20.20.2-0.1
Epididymis fat weight3.99.010.33.23.1-3.0-3.0-2.83.23.23.23.21.9
Delta time in closed arm before/after self-admin0.10.10.30.10.00.10.10.30.30.50.50.5-0.5
Delta time in open arm before/after self-admin1.31.33.7-0.6-0.60.40.50.4-0.7-1.9-1.9-1.9-0.1
Diff in mean of infusions in LGA sessions0.10.10.20.10.2-0.4-0.4-0.4-0.10.00.00.00.4
Delay discount exponential model param0.00.00.2-0.1-0.10.20.2-0.0-0.2-0.1-0.1-0.1-0.4
Extinction: sum of active levers before priming0.10.10.50.30.3-0.3-0.3-0.70.00.10.10.10.5
Active lever presses in extinction session 61.61.62.1-1.2-1.21.41.41.1-1.0-1.2-1.2-1.2-1.4
Bone: final force0.20.30.5-0.6-0.60.60.70.7-0.6-0.5-0.5-0.5-0.3
Bone: final moment0.30.40.6-0.7-0.70.70.70.8-0.6-0.6-0.6-0.6-0.5
Food consumed during 24 hour testing period0.60.71.3-0.5-0.60.70.70.8-0.3-1.1-1.1-1.1-0.9
Glucose0.50.81.5-0.9-0.90.40.50.5-1.1-1.2-1.2-1.2-0.4
Heart weight0.00.00.0-0.1-0.10.20.10.1-0.1-0.0-0.0-0.0-0.1
Delay discount hyperbolic model param0.10.10.3-0.2-0.20.30.30.1-0.2-0.2-0.2-0.2-0.5
Intermittent access intake day 1-15 change1.21.21.91.31.3-1.4-1.4-1.31.20.70.70.70.7
Intermittent access intake escalation1.41.41.81.31.3-1.3-1.3-1.31.31.01.01.00.4
Intermittent access intake escalation 20.20.20.50.60.6-0.7-0.7-0.70.40.10.10.10.5
Intermitt. access day 1 inactive lever presses2.62.83.7-1.9-1.91.91.91.8-1.8-1.5-1.5-1.5-1.2
Intermitt. access day 15 inactive lever presses0.91.01.4-1.1-1.11.11.11.1-1.0-0.8-0.8-0.8-1.2
Intermitt. access escalation Index0.20.20.3-0.6-0.60.50.50.5-0.5-0.1-0.1-0.1-0.2
Intermittent access day 1 total infusions0.20.30.40.50.5-0.5-0.4-0.30.70.60.60.60.1
Intermittent access day 15 total infusions1.41.62.11.41.4-1.5-1.5-1.31.51.11.11.10.4
Intermittent access terminal intake (last 3 days)1.51.72.91.51.5-1.7-1.7-1.41.50.70.70.70.8
Intermittent access total infusions0.50.50.80.80.8-0.9-0.9-0.60.90.70.70.70.1
Intermittent access day 1 locomotion0.30.41.00.80.8-0.7-0.7-0.51.00.10.10.10.3
Intermittent access day 15 total locomotion0.10.10.50.40.4-0.3-0.3-0.20.70.20.20.2-0.5
Intermittent access total locomotion0.20.20.50.60.6-0.6-0.6-0.30.70.20.20.2-0.1
Intermittent access standard deviation2.93.14.32.02.0-2.1-2.1-1.92.01.31.31.31.2
Left kidney weight1.43.96.4-2.0-2.02.32.32.4-1.5-1.5-1.5-1.5-2.5
Right kidney weight0.92.55.1-1.5-1.62.01.92.0-1.1-1.0-1.0-1.0-2.3
Cocaine induced anxiety2.02.33.5-1.7-1.61.51.41.2-1.9-1.6-1.6-1.6-0.6
Post-drug Anxiety1.61.82.8-1.4-1.31.21.10.9-1.7-1.6-1.6-1.6-0.3
Baseline Anxiety1.51.62.01.31.3-1.4-1.4-1.21.31.21.21.21.0
Tail length3.811.517.7-3.4-3.53.63.53.5-3.0-3.0-3.0-3.0-4.2
Length with tail5.419.623.1-4.6-4.64.84.74.8-4.0-4.0-4.0-4.0-4.7
Length without tail2.55.57.5-2.5-2.52.62.62.7-2.2-2.2-2.2-2.2-1.6
Times rat made contact with spout0.30.41.0-0.4-0.40.20.20.2-0.7-1.0-1.0-1.00.3
Lifetime Intake0.10.20.30.50.5-0.6-0.5-0.30.60.20.20.2-0.2
Liver weight, left2.43.84.7-2.0-2.01.71.81.7-2.1-2.2-2.2-2.2-1.7
Liver weight, right0.00.00.1-0.1-0.10.00.00.1-0.1-0.2-0.2-0.20.4
Locomotor activity0.10.20.4-0.5-0.50.60.50.6-0.4-0.4-0.4-0.40.2
Locomotor testing distance0.40.60.7-0.8-0.80.80.70.8-0.7-0.9-0.9-0.9-0.0
Locomotor testing rearing1.52.46.21.51.5-1.5-1.7-1.51.21.21.21.22.5
Locomotion in novel chamber6.37.810.4-2.8-2.82.83.02.7-2.6-2.6-2.6-2.6-3.2
Locomotion in novel chamber post-restriction0.10.10.30.20.10.10.2-0.00.50.50.50.5-0.4
Fecal boli incidents, locomotor time 12.42.73.21.71.7-1.7-1.6-1.81.61.61.61.61.4
Change in fecal boli incidents, locomotor task1.91.85.9-1.2-1.31.71.71.7-0.5-0.5-0.5-0.5-2.4
Time >=10cm from walls, locomotor time 10.30.30.50.50.5-0.4-0.3-0.40.70.70.70.70.0
Bouts of movement, locomotor time 11.61.82.61.41.4-1.6-1.6-1.31.21.21.21.21.1
Total resting periods, locomotor time 11.51.62.31.41.4-1.5-1.5-1.21.21.21.21.20.9
Rest time, locomotor task time 10.10.10.2-0.1-0.1-0.3-0.2-0.1-0.4-0.5-0.5-0.50.1
Distance moved, locomotor task time 10.10.20.50.40.4-0.1-0.2-0.30.40.40.40.40.7
Vertical activity count, locomotor time 10.50.50.8-0.7-0.70.60.60.7-0.9-0.9-0.9-0.90.4
Time >=10cm from walls, locomotor time 20.40.50.7-0.7-0.70.60.60.4-0.8-0.8-0.8-0.8-0.3
Bouts of movement, locomotor time 21.71.82.4-1.4-1.41.41.31.5-1.3-1.4-1.4-1.4-0.9
Total resting periods, locomotor time 21.31.41.9-1.2-1.31.21.11.4-1.1-1.2-1.2-1.2-0.9
Rest time, locomotor task time 20.20.20.3-0.4-0.40.20.20.4-0.5-0.5-0.5-0.5-0.4
Distance moved, locomotor task time 20.20.31.20.50.5-0.4-0.5-0.50.30.30.30.31.1
Vertical activity count, locomotor time 20.40.40.8-0.5-0.50.30.30.4-0.8-0.8-0.8-0.80.9
Light reinforcement 10.00.00.1-0.0-0.1-0.00.10.10.20.10.10.1-0.3
Light reinforcement 22.02.73.01.71.7-1.7-1.6-1.61.71.71.71.71.5
Bone: marrow area0.10.20.50.40.3-0.1-0.1-0.10.70.70.70.7-0.3
Bone: maximum diameter0.10.20.50.20.3-0.7-0.7-0.7-0.0-0.1-0.1-0.10.7
Bone: maximum force0.20.30.4-0.6-0.60.50.50.6-0.6-0.6-0.6-0.6-0.2
Bone: maximum moment0.20.30.3-0.6-0.60.60.50.6-0.6-0.5-0.5-0.5-0.3
Mean time between licks in bursts0.40.61.41.00.9-0.6-0.6-0.71.20.70.70.70.3
Mean num. licks in bursts0.10.10.1-0.2-0.20.20.20.2-0.1-0.4-0.4-0.4-0.2
Cd content in liver2.02.23.6-1.2-1.31.81.81.8-0.5-1.4-1.4-1.4-1.9
Co content in liver1.11.31.9-1.2-1.21.41.41.4-1.0-0.8-0.8-0.8-1.1
Cu content in liver1.41.62.41.41.5-1.6-1.6-1.61.10.70.70.71.5
Fe content in liver0.30.41.00.60.6-0.7-0.7-0.70.30.30.30.31.0
K content in liver0.10.10.2-0.3-0.30.20.20.2-0.4-0.4-0.4-0.4-0.1
Mg content in liver0.10.10.2-0.4-0.40.40.30.4-0.4-0.1-0.1-0.1-0.4
Mn content in liver0.50.61.7-0.5-0.60.90.90.9-0.10.70.70.7-1.3
Na content in liver0.40.40.80.50.5-0.8-0.8-0.80.10.40.40.40.9
Rb content in liver0.80.91.6-1.2-1.21.31.21.3-1.0-0.2-0.2-0.2-1.0
Se content in liver0.10.10.20.30.3-0.1-0.2-0.10.5-0.5-0.5-0.5-0.1
Sr content in liver0.70.71.2-0.6-0.60.70.70.7-0.4-1.1-1.1-1.1-0.7
Zn content in liver0.30.30.6-0.4-0.40.30.30.3-0.4-0.8-0.8-0.8-0.5
Bone: minimum diameter0.81.41.8-1.2-1.31.31.31.3-1.1-1.0-1.0-1.0-1.3
Time in familiar zone, hab. session 10.10.10.30.30.3-0.0-0.1-0.00.50.50.50.50.2
Time in novel zone, hab. session 10.30.30.40.50.5-0.6-0.6-0.60.40.40.40.40.3
Total zone transitions, hab. session 10.30.51.00.60.5-0.2-0.2-0.21.01.01.01.0-0.1
Total locomotion distance, hab. session 10.40.61.7-0.6-0.71.01.01.1-0.0-0.1-0.1-0.1-1.3
Locomotion velocity, hab. session 10.81.22.1-1.1-1.11.31.31.4-0.7-0.7-0.7-0.7-1.5
Time in familiar zone, hab. session 20.20.20.30.50.5-0.2-0.3-0.30.60.60.60.60.5
Time in novel zone, hab. session 20.10.10.20.30.3-0.4-0.3-0.40.30.30.30.3-0.1
Total zone transitions, hab. session 20.81.01.11.01.0-1.0-1.0-1.01.01.11.11.10.6
Total locomotion distance, hab. session 20.30.40.7-0.7-0.70.50.50.6-0.6-0.6-0.6-0.6-0.9
Locomotion velocity, hab. session 20.50.60.9-0.8-0.80.60.60.7-0.8-0.8-0.8-0.8-1.0
Novel to familiar place preference ratio0.50.60.70.80.8-0.9-0.8-0.90.60.70.70.70.7
Novelty place preference0.30.30.40.60.6-0.7-0.6-0.70.50.50.50.50.5
Time in novel zone, NPP test0.20.20.20.50.5-0.5-0.5-0.50.40.50.50.50.4
Total zone transitions, NPP test0.10.20.50.1-0.00.30.30.40.50.50.50.5-0.7
Total locomotion distance, NPP test0.20.20.7-0.4-0.40.60.60.80.1-0.0-0.0-0.0-0.8
Locomotion velocity, NPP test0.20.20.7-0.4-0.50.60.60.8-0.0-0.1-0.1-0.1-0.9
Intraocular pressure0.10.10.30.20.2-0.1-0.2-0.20.30.30.30.30.5
Delta distance traveled before/after self-admin0.60.62.5-0.5-0.50.70.71.1-0.2-0.6-0.6-0.6-1.6
Delta ambulatory time before/after self-admin1.71.84.7-1.1-1.21.41.41.7-0.8-1.1-1.1-1.1-2.2
Parametrial fat weight0.00.00.10.20.2-0.3-0.3-0.20.10.10.10.10.3
Pavlov. Cond. lever latency0.70.91.3-1.0-1.01.11.01.0-1.0-0.9-0.9-0.9-0.9
Pavlov. Cond. magazine entry latency0.50.60.80.80.8-0.8-0.8-0.70.80.70.70.70.9
Pavlov. Cond. change in total contacts0.30.30.40.50.5-0.6-0.6-0.60.50.40.40.40.5
Pavlov. Cond. index score1.01.31.41.21.2-1.2-1.2-1.11.21.11.11.11.0
Pavlov. Cond. latency score0.70.91.11.01.0-1.1-1.0-1.01.00.90.90.90.9
Pavlov. Cond. lever contacts1.21.42.01.21.2-1.4-1.3-1.31.11.01.01.01.2
Pavlov. Cond. magazine entry number0.91.11.5-1.1-1.11.00.90.9-1.2-1.1-1.1-1.1-0.7
Pavlov. Cond. intertrial magazine entries5.56.77.3-2.7-2.72.72.72.6-2.6-2.6-2.6-2.6-2.3
Pavlov. Cond. lever-magazine prob. diff.0.81.01.21.01.0-1.1-1.1-1.01.00.90.90.90.9
Pavlov. Cond. response bias1.11.31.61.21.2-1.2-1.1-1.11.31.21.21.20.8
Pavlov. Cond. lever latency1.21.63.0-1.5-1.51.21.21.2-1.7-1.1-1.1-1.1-0.5
Pavlov. Cond. magazine entry latency3.33.86.02.32.2-2.0-2.0-2.02.41.71.71.71.2
Pavlov. Cond. change in total contacts3.14.35.52.32.3-2.1-2.1-2.32.21.81.81.81.8
Pavlov. Cond. index score3.24.06.42.32.3-1.9-1.9-2.02.51.91.91.91.1
Pavlov. Cond. latency score3.44.26.12.32.3-1.9-1.9-2.02.52.02.02.01.3
Pavlov. Cond. lever contacts1.82.44.21.91.8-1.5-1.5-1.62.01.31.31.30.7
Pavlov. Cond. magazine entry number2.73.34.5-2.0-2.01.81.81.8-2.1-1.9-1.9-1.9-1.0
Pavlov. Cond. intertrial magazine entries5.47.18.1-2.8-2.72.52.62.5-2.8-2.8-2.8-2.8-2.1
Pavlov. Cond. lever-magazine prob. diff.3.74.76.92.52.4-2.1-2.1-2.22.62.12.12.11.3
Pavlov. Cond. response bias2.12.95.42.12.0-1.6-1.7-1.72.31.51.51.50.6
Time in closed arm before self-admin3.13.55.62.12.1-2.0-2.0-2.31.91.21.21.22.4
Time in closed arm after self-admin1.01.01.91.21.2-1.0-1.0-1.01.40.80.80.80.7
Time in open arm before self-admin4.75.17.7-2.6-2.62.62.62.6-2.3-1.1-1.1-1.1-2.8
Time in open arm after self-admin3.64.04.3-2.0-2.02.02.12.0-1.9-2.0-2.0-2.0-1.8
Bone: periosteal estimation0.00.10.1-0.3-0.30.20.20.2-0.2-0.2-0.2-0.2-0.4
Bone: periosteal perimeter0.00.00.0-0.00.0-0.1-0.2-0.1-0.1-0.1-0.1-0.10.0
Bone: post-yield work1.62.23.3-1.5-1.61.81.81.8-1.2-1.3-1.3-1.3-1.1
Progressive ratio test 1 active lever presses0.10.10.10.00.0-0.2-0.20.10.1-0.4-0.4-0.4-0.1
Progressive ratio test 1 breakpoint0.10.10.20.20.2-0.5-0.5-0.00.3-0.3-0.3-0.30.1
Progressive ratio test 1 inactive lever presses2.52.83.8-1.9-1.91.71.71.9-1.8-1.5-1.5-1.5-1.2
Progressive ratio test 2 active lever presses0.10.10.30.00.0-0.1-0.10.10.00.50.50.5-0.4
Progressive ratio test 2 breakpoint0.10.10.5-0.1-0.10.00.10.20.00.40.40.4-0.7
Progressive ratio test 2 inactive lever presses0.80.91.8-1.0-1.00.90.90.9-1.1-0.7-0.7-0.7-1.3
Incentive Sensitization - Responses0.20.20.70.0-0.0-0.0-0.00.10.10.80.80.8-0.6
Incentive Sensitization - Breakpoint0.30.30.6-0.1-0.10.10.10.2-0.00.80.80.8-0.8
Sum of active levers in priming session hrs 5-60.60.51.20.70.8-1.0-1.0-1.10.40.50.50.50.7
Progressive ratio0.30.40.8-0.6-0.60.40.70.5-0.6-0.6-0.6-0.6-0.9
Food seeking constrained by brief footshock1.01.22.0-1.1-1.10.60.70.9-1.3-1.4-1.4-1.40.2
Seeking ratio, punishment vs. effort0.10.10.6-0.2-0.20.1-0.00.2-0.3-0.4-0.4-0.40.8
Retroperitoneal fat weight0.20.81.00.90.9-1.0-1.0-0.90.90.90.90.90.6
Reaction time number correct3.34.75.2-2.3-2.32.12.02.0-2.2-2.3-2.3-2.3-2.0
Reaction time mean minus median0.10.10.20.40.4-0.3-0.4-0.10.30.50.50.50.2
Reaction time mean minus median AUC0.10.10.20.30.2-0.1-0.20.10.30.50.50.5-0.2
Reaction time num false alarms1.01.31.5-1.2-1.21.01.01.1-1.1-1.2-1.2-1.2-1.2
Reaction time num false alarms AUC1.41.92.1-1.5-1.51.21.21.3-1.4-1.5-1.5-1.5-1.4
Reaction time trials correct on left3.34.75.2-2.3-2.32.12.02.0-2.2-2.3-2.3-2.3-2.0
Reaction time trials on left3.34.75.2-2.3-2.32.12.12.1-2.2-2.3-2.3-2.3-2.0
Reaction time mean0.71.01.51.11.0-0.9-0.9-0.71.11.21.21.20.6
Reaction time mean AUC0.40.61.00.80.8-0.6-0.6-0.40.81.01.01.00.4
Median of all reaction times0.40.50.90.70.7-0.6-0.5-0.30.81.01.01.00.3
Reaction time omissions1.11.52.3-1.3-1.31.31.21.5-1.1-1.0-1.0-1.0-1.5
Reaction time false alarm rate0.10.10.1-0.3-0.30.20.20.3-0.2-0.3-0.3-0.3-0.3
Reaction time premature initiation rate0.70.91.3-1.0-1.01.01.00.9-1.1-1.0-1.0-1.0-0.5
Reaction time premature initiations2.53.54.0-1.9-1.91.81.91.7-2.0-2.0-2.0-2.0-1.4
Std. dev. reaction times0.30.50.70.70.7-0.6-0.6-0.40.70.90.90.90.3
Reaction time trials completed3.34.75.2-2.3-2.32.12.12.1-2.2-2.3-2.3-2.3-2.0
Reaction time trials AUC3.55.15.6-2.3-2.32.12.12.1-2.3-2.4-2.4-2.4-2.1
Run reversals in cocaine runway, females1.11.11.71.11.1-1.2-1.1-1.30.91.01.01.00.4
Run reversals in cocaine runway, males0.50.51.0-0.7-0.60.40.40.4-1.0-1.0-1.0-1.00.5
Latency to leave start box in cocaine runway0.20.20.50.40.5-0.6-0.6-0.70.20.20.20.20.5
Latency to leave start box in cocaine runway, F0.40.41.20.50.6-0.8-0.8-1.00.10.10.10.11.1
Latency to leave start box in cocaine runway, M0.20.20.50.40.4-0.7-0.5-0.50.30.30.30.30.4
Std. dev. time between licks in bursts0.30.41.00.50.40.10.10.11.00.90.90.9-0.6
Total sessions with >9 infusions0.10.10.20.10.1-0.2-0.10.00.1-0.4-0.4-0.4-0.4
Short access day 1 total inactive lever presses0.10.10.3-0.1-0.10.40.40.30.20.30.30.3-0.6
Short access day 10 total inactive lever presses0.60.61.2-0.9-0.91.01.01.1-0.60.10.10.1-1.0
Short access day 1 total infusions0.60.61.1-0.6-0.60.60.60.6-0.5-1.1-1.1-1.1-0.8
Short access day 10 total infusions0.20.20.40.50.5-0.6-0.6-0.40.60.20.20.2-0.0
Short access total infusions0.10.10.20.40.4-0.4-0.4-0.20.4-0.4-0.4-0.4-0.3
Short access day 1 locomotion0.20.20.50.60.6-0.5-0.5-0.50.7-0.2-0.2-0.20.2
Short access day 10 total locomotion0.40.40.80.80.8-0.9-0.9-0.60.8-0.0-0.0-0.00.7
Short access total locomotion0.20.20.60.20.2-0.3-0.3-0.00.2-0.8-0.8-0.80.0
One hour access (0.3 mA shock)0.10.10.2-0.3-0.30.20.20.3-0.3-0.5-0.5-0.5-0.4
Compulsive drug intake0.10.10.50.00.00.20.2-0.00.20.10.10.10.7
One hour access (shock baseline)0.00.10.20.10.1-0.3-0.3-0.10.1-0.2-0.2-0.2-0.4
Social response proportion0.40.40.6-0.7-0.60.70.60.7-0.8-0.6-0.6-0.6-0.4
Social responses0.00.00.00.10.1-0.1-0.1-0.00.10.20.20.20.2
Social time1.62.13.9-1.4-1.41.81.71.6-1.1-1.0-1.0-1.0-2.0
Soleus weight0.10.20.6-0.2-0.30.60.50.60.20.20.20.2-0.7
Bone: stiffness1.32.02.3-1.5-1.51.51.51.5-1.4-1.4-1.4-1.4-0.9
Tibialis anterior weight0.31.11.3-1.1-1.11.11.01.2-1.0-1.0-1.0-1.0-0.7
Time to tail flick, vehicle, before self-admin0.70.71.2-0.8-0.80.70.70.8-0.71.11.11.1-0.8
Time to tail flick, vehicle, after self-admin0.10.10.40.10.10.10.00.20.5-0.2-0.2-0.2-0.6
Time to tail flick, test, before self-admin0.00.00.1-0.2-0.20.00.10.2-0.30.20.20.20.3
Time to tail flick, test, after self-admin1.41.42.0-1.4-1.41.31.31.4-1.3-0.7-0.7-0.7-1.4
Delta time to tail flick, vehicle, before/after SA0.40.41.40.10.10.0-0.00.10.2-1.2-1.2-1.2-0.2
Delta time to tail flick, test, before/after SA1.61.42.3-1.1-1.11.21.11.2-0.8-1.3-1.3-1.3-1.5
Tibia length0.20.50.9-0.7-0.60.30.30.3-0.9-0.9-0.9-0.9-0.2
Ambulatory time before self-admin0.70.82.70.60.7-1.0-1.1-1.30.3-0.1-0.1-0.11.7
Ambulatory time after self-admin0.00.00.00.10.1-0.1-0.1-0.20.1-0.1-0.1-0.10.1
Bone: tissue strength0.00.00.1-0.0-0.0-0.2-0.2-0.2-0.2-0.2-0.2-0.20.4
Total heroin consumption0.30.41.1-0.8-0.70.40.40.4-1.1-0.5-0.5-0.5-0.2
Bone: trabecular number0.10.20.4-0.4-0.50.60.60.6-0.3-0.2-0.2-0.2-0.5
Bone: trabecular spacing0.10.10.20.40.4-0.4-0.3-0.40.50.30.30.3-0.2
Bone: trabecular thickness0.10.10.2-0.3-0.30.20.20.2-0.4-0.3-0.3-0.30.1
Bone: trabecular tissue density0.20.30.5-0.3-0.2-0.1-0.2-0.1-0.7-0.7-0.7-0.70.7
Water consumed over 24 hours2.73.23.8-2.0-1.91.71.71.8-2.0-1.8-1.8-1.8-1.4
Number of responses in last shaping day0.50.50.80.70.7-0.8-0.7-0.50.80.60.60.60.9