Hub : Genes

Kctd21

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Kctd21 0.13 0.06 1.3e-12 0.13 0.13 0.12 0.13 4.8e-12 3.3e-12 8.5e-11 7.7e-12
2 Adipose alternative TSS XM_039087670.1 0.03 0.02 4.1e-03 0 0.01 0.01 0 2.0e-01 1.8e-02 3.2e-02 7.8e-02
3 Liver alternative polyA XM_006229781.4 0.03 0.02 3.3e-03 0.02 0 0.01 0.01 2.2e-03 7.7e-02 5.6e-02 2.9e-02
4 Adipose alternative TSS XM_006229781.4 0.03 0.02 4.0e-03 0 0.01 0.01 0 1.4e-01 2.0e-02 3.4e-02 9.1e-02
5 Adipose isoform ratio XM_006229781.4 0.03 0.02 1.4e-03 0.02 0.01 0.01 0.01 1.1e-03 1.4e-02 2.6e-02 1.8e-02
6 Adipose mRNA stability Kctd21 0.08 0.04 1.8e-07 0.03 0.04 0.03 0.04 6.0e-04 9.3e-06 3.1e-04 8.3e-05
7 Adipose gene expression Kctd21 0.05 0.03 1.6e-05 0.02 0.03 0.02 0.02 1.6e-03 3.2e-04 1.2e-03 1.1e-03
8 PL gene expression Kctd21 0.1 0.05 4.6e-10 0.09 0.09 0.09 0.09 2.8e-10 4.7e-10 4.4e-10 4.6e-10
9 Brain gene expression Kctd21 0.04 0.03 1.7e-03 0.03 0.02 0.03 0.02 5.9e-04 2.5e-03 1.5e-03 2.3e-03
10 NAcc gene expression Kctd21 0.05 0.03 7.8e-05 0.04 0.03 0.03 0.03 4.5e-05 2.0e-04 5.6e-04 9.7e-05
11 RMTg alternative TSS NM_001109151.1 0.21 0.13 6.6e-03 -0 0.02 -0 -0 3.8e-01 1.2e-01 3.7e-01 3.4e-01
12 BLA gene expression Kctd21 0.08 0.05 1.4e-03 0.02 0.03 0.04 0.02 3.6e-02 1.0e-02 3.6e-03 4.6e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.20.40.1-0.00.6-0.00.20.10.6-0.5-0.6-0.60.6-0.2
Area under the delay curve0.50.51.31.1-1.01.11.0-0.80.9-0.3-0.3-0.2-0.20.7-0.0
BMI with tail0.82.64.7-1.91.6-2.2-1.60.4-1.9-1.11.71.81.6-0.92.0
BMI without tail4.810.017.3-3.42.8-4.2-2.70.7-3.3-2.43.53.73.5-2.93.4
Body weight2.18.914.7-3.12.5-3.8-2.40.2-3.1-2.53.53.53.5-2.23.5
Weight adjusted by age1.11.33.5-0.1-0.3-0.50.3-1.10.2-1.51.71.51.7-1.9-0.1
Bone surface0.91.53.21.6-1.71.51.7-1.81.7-0.90.50.40.4-0.5-0.2
Bone volume0.50.92.01.1-1.21.11.2-1.41.1-1.00.70.60.6-0.50.2
Breakpoint value in progressive ratio session0.20.20.40.5-0.40.50.4-0.10.50.4-0.6-0.5-0.50.4-0.6
Number of licking bursts1.51.73.7-1.81.9-1.5-1.91.7-1.90.8-0.2-0.2-0.20.30.4
Context. condit. distance diff. score2.42.96.42.5-2.42.22.4-2.02.5-0.4-0.3-0.3-0.30.0-1.1
Locomotion velocity, session 11.11.22.01.2-1.01.31.0-0.21.20.7-1.2-1.3-1.30.9-1.4
Locomotion distance, session 10.40.51.11.0-1.00.81.0-0.31.10.1-0.5-0.5-0.50.2-0.9
Locomotion velocity, session 20.40.50.90.9-1.00.91.0-0.80.9-0.50.20.20.2-0.2-0.5
Locomotion distance, session 20.00.00.1-0.10.1-0.1-0.10.2-0.3-0.20.10.00.00.3-0.1
Locomotion velocity, session 30.20.20.50.7-0.60.60.6-0.50.7-0.1-0.2-0.2-0.20.2-0.1
Locomotion distance, session 31.71.83.81.9-1.81.71.8-1.41.9-0.0-0.7-0.7-0.70.5-0.9
Stereotopy head waving bouts, day 32.02.45.1-2.32.2-2.0-2.22.0-2.10.90.20.10.2-0.70.6
Stereotopy head waving duration, day 30.30.30.8-0.60.7-0.1-0.80.7-0.80.4-0.4-0.4-0.40.90.3
Locomotion velocity, session 70.30.31.00.8-0.70.70.7-0.60.7-0.0-0.2-0.2-0.30.2-1.0
Locomotion distance, session 70.70.92.01.1-1.20.61.2-1.41.2-0.90.60.50.5-0.6-0.5
Stereotopy head waving bouts, day 70.30.31.20.3-0.20.60.20.10.40.7-0.7-0.7-0.60.1-1.1
Stereotopy head waving duration, day 70.10.20.50.5-0.50.70.5-0.40.5-0.1-0.1-0.1-0.10.1-0.4
Locomotion velocity, session 84.65.511.63.4-3.23.43.2-2.73.1-0.6-0.6-0.8-0.91.3-1.7
Locomotion distance, session 81.01.53.11.8-1.81.61.7-1.41.7-0.5-0.1-0.2-0.20.2-0.8
Degree of sensitization distance1.41.42.9-1.00.7-1.5-0.7-0.0-0.8-1.21.71.61.5-1.50.9
Degree of sensitization stereotypy1.71.83.61.8-1.71.91.7-1.21.90.3-0.8-0.8-0.80.3-1.6
Conditioned locomotion0.30.31.50.10.10.5-0.10.2-0.20.4-0.7-0.7-0.71.20.2
Cocaine response after cond. corrected0.10.20.60.3-0.4-0.00.4-0.30.5-0.40.40.40.4-0.70.3
Cocaine response after cond. not corrected0.10.10.50.5-0.50.20.5-0.20.70.2-0.1-0.1-0.1-0.5-0.2
Cocaine response before conditioning0.50.71.8-0.10.30.1-0.30.90.01.4-1.1-1.1-1.10.4-1.1
Saline control response0.70.92.60.1-0.3-0.20.3-1.0-0.1-1.61.21.21.2-0.21.4
Bone: connectivity density0.71.12.21.2-1.01.51.0-0.41.20.9-1.1-1.1-1.10.6-1.1
Bone: cortical apparent density0.20.30.7-0.70.7-0.4-0.70.5-0.8-0.00.10.10.10.30.8
Bone: cortical area0.71.02.00.4-0.7-0.10.7-1.30.5-1.41.41.31.3-1.10.3
Bone: cortical porosity0.20.20.50.10.00.1-0.10.40.10.7-0.7-0.7-0.70.3-0.6
Bone: cortical porosity0.20.30.7-0.10.2-0.1-0.20.60.10.8-0.7-0.8-0.80.0-0.7
Bone: cortical thickness0.00.10.2-0.30.2-0.5-0.20.1-0.2-0.10.40.30.3-0.4-0.1
Bone: cortical thickness0.91.02.51.3-1.50.71.5-1.21.6-0.50.10.00.0-0.7-0.7
Bone: cortical tissue density0.20.30.7-0.70.7-0.4-0.70.6-0.80.1-0.00.0-0.00.40.7
Condit. Reinf. active minus inactive responses1.11.22.5-0.60.3-1.3-0.3-0.3-0.6-1.41.51.41.4-1.11.6
Condit. Reinf. active-inactive response ratio1.11.23.5-0.70.5-1.4-0.5-0.2-0.7-1.31.51.31.3-0.91.9
Condit. Reinf. active responses0.60.81.4-0.80.6-1.2-0.60.1-0.8-0.91.11.00.9-0.71.2
Condit. Reinf. inactive responses0.00.00.0-0.10.2-0.0-0.10.1-0.10.00.00.00.0-0.1-0.2
Incentive salience index mean0.70.81.8-0.1-0.2-0.70.2-0.70.0-1.31.31.21.2-1.11.0
Condit. Reinf. lever presses0.40.51.00.9-1.00.71.0-1.00.9-0.60.30.20.2-0.2-0.3
Condit. Reinf. active minus inactive responses3.03.77.61.5-2.00.72.0-2.81.6-2.72.12.12.1-1.50.9
Condit. Reinf. active-inactive response ratio1.61.63.81.4-1.61.01.6-1.91.4-1.61.01.01.0-0.50.2
Condit. Reinf. active responses3.85.311.91.5-2.00.42.1-3.11.5-3.42.82.82.8-1.91.4
Condit. Reinf. inactive responses1.62.04.6-0.1-0.3-0.80.3-1.2-0.1-2.22.12.12.1-1.51.4
Condit. Reinf. lever presses5.27.016.73.3-3.52.63.6-4.12.9-3.01.51.51.5-0.10.6
Condit. Reinf. lever reinforcers received4.05.711.91.8-2.30.72.4-3.31.8-3.42.72.72.7-1.91.2
Conditioned reinforcement - actives2.42.46.32.2-2.12.12.1-1.42.50.3-0.6-0.6-0.7-0.5-0.9
Conditioned reinforcement - inactives0.20.22.3-0.00.1-0.1-0.10.30.10.5-0.2-0.3-0.2-0.2-1.5
Conditioned locomotion2.02.45.52.1-2.02.12.0-1.22.30.6-0.8-0.9-0.9-0.1-1.7
Patch foraging indifference point 0 sec0.71.12.71.0-1.20.71.2-1.60.9-1.61.00.91.0-0.10.6
Patch foraging indifference point AUC0.20.20.40.2-0.4-0.00.4-0.50.3-0.60.60.60.5-0.60.3
Delay disc. indifference point, 0s delay0.40.41.20.4-0.60.10.6-0.70.7-0.60.70.70.6-1.1-0.6
Delay disc. indifference point, 16s delay0.70.72.80.9-0.71.20.7-0.30.50.1-1.0-0.8-0.81.7-0.2
Delay disc. indifference point, 2s delay0.50.51.10.9-1.00.81.0-1.01.0-0.30.20.20.2-0.2-0.5
Delay disc. indifference point, 24s delay0.30.31.50.2-0.10.50.10.0-0.10.1-0.5-0.5-0.51.20.7
Delay disc. indifference point, 4s delay0.91.02.20.9-1.10.61.1-1.50.9-1.21.01.01.0-0.60.2
Delay disc. indifference point, 8s delay0.70.81.81.2-1.21.31.2-0.91.0-0.3-0.3-0.4-0.30.80.4
Indifference point function ln k0.40.51.70.7-0.50.90.5-0.20.40.4-0.8-0.9-0.81.3-0.3
Indifference point function log k0.40.51.70.7-0.50.90.5-0.20.40.4-0.8-0.9-0.81.3-0.3
Patch foraging total patch changes 0 sec0.71.12.61.1-1.30.91.3-1.60.9-1.40.80.70.80.00.6
Patch foraging total patch changes 12 sec0.71.02.40.3-0.7-0.00.7-0.90.6-1.21.41.31.3-1.50.1
Patch foraging total patch changes 18 sec1.11.43.00.8-1.10.31.1-1.40.9-1.71.41.41.4-1.10.7
Patch foraging total patch changes 24 sec0.81.02.40.4-0.7-0.10.7-0.90.7-1.31.21.31.3-1.60.8
Patch foraging total patch changes 6 sec0.10.10.70.2-0.10.20.1-0.3-0.1-0.20.0-0.1-0.10.80.4
Patch foraging time to switch 0 sec1.62.56.0-1.92.1-1.4-2.12.5-1.71.9-0.9-0.9-1.00.2-0.8
Patch foraging water rate 0 sec1.21.94.31.8-1.91.32.0-2.11.7-1.30.40.40.5-0.20.3
Patch foraging water rate 12 sec0.81.22.51.5-1.41.51.4-1.61.1-1.00.00.10.00.90.5
Patch foraging water rate 18 sec0.50.71.70.9-1.00.61.0-1.30.7-1.30.60.40.50.10.8
Patch foraging water rate 24 sec0.91.22.51.5-1.31.61.3-0.91.1-0.0-0.8-0.9-0.91.5-0.5
Patch foraging water rate 6 sec0.60.81.61.2-1.01.31.0-0.70.90.0-0.8-0.8-0.81.1-0.5
Seeking ratio, delayed vs. immediate footshock0.10.10.30.0-0.00.00.00.30.30.4-0.2-0.3-0.3-0.4-0.6
Distance traveled before self-admin0.10.10.2-0.30.3-0.4-0.30.4-0.30.10.00.10.10.10.5
Distance traveled after self-admin1.01.12.2-0.81.1-0.5-1.11.5-1.01.3-1.1-1.1-1.11.2-0.0
Extensor digitorum longus weight0.31.02.4-0.40.2-0.7-0.2-0.7-0.6-1.51.51.51.5-0.51.2
Bone: elastic displacement0.30.40.9-0.20.30.0-0.40.5-0.30.8-0.9-0.8-0.90.9-0.6
Bone: elastic work1.11.53.30.4-0.00.9-0.00.60.21.5-1.7-1.8-1.81.8-1.2
Bone: endosteal estimation1.02.14.30.8-1.20.31.2-1.80.9-2.11.91.91.9-1.70.7
Bone: endosteal perimeter1.42.96.11.6-1.91.21.9-2.51.6-2.31.81.71.7-1.10.4
Epididymis fat weight2.45.510.1-2.41.8-3.2-1.80.4-1.9-1.42.82.82.7-3.12.6
Delta time in closed arm before/after self-admin1.11.14.5-0.1-0.1-0.20.1-0.7-0.5-1.81.21.21.20.42.1
Delta time in open arm before/after self-admin0.80.81.60.8-1.00.31.0-1.31.0-0.80.80.90.9-1.20.0
Diff in mean of infusions in LGA sessions1.61.73.8-1.71.9-1.3-1.91.6-1.90.9-0.3-0.5-0.50.80.4
Delay discount exponential model param0.50.51.3-1.00.9-1.1-0.90.8-0.80.20.30.30.3-0.8-0.2
Extinction: sum of active levers before priming0.30.30.70.2-0.3-0.10.3-0.60.1-0.80.70.80.7-0.30.7
Active lever presses in extinction session 60.40.40.90.8-0.70.50.7-0.10.90.5-0.8-0.5-0.50.0-0.8
Bone: final force0.20.30.60.7-0.70.70.7-0.60.70.1-0.2-0.2-0.20.4-0.7
Bone: final moment0.20.30.50.7-0.70.70.7-0.70.7-0.1-0.0-0.1-0.10.2-0.7
Food consumed during 24 hour testing period0.81.02.51.4-1.31.61.3-0.91.30.1-0.5-0.5-0.50.5-0.6
Glucose0.20.30.90.8-0.80.70.8-0.90.7-0.30.20.00.00.4-0.2
Heart weight0.60.91.81.2-1.30.91.3-1.31.2-0.90.30.40.5-0.30.7
Delay discount hyperbolic model param0.60.61.2-1.11.1-1.1-1.11.0-1.00.40.10.10.0-0.4-0.1
Intermittent access intake day 1-15 change1.41.42.91.7-1.61.71.6-1.21.60.0-0.5-0.5-0.50.4-0.9
Intermittent access intake escalation1.61.63.31.8-1.71.81.7-1.41.8-0.2-0.4-0.4-0.40.4-0.7
Intermittent access intake escalation 20.30.30.70.6-0.70.50.7-0.70.9-0.20.30.20.3-0.70.0
Intermitt. access day 1 inactive lever presses0.40.40.8-0.70.7-0.9-0.70.9-0.30.8-0.0-0.20.0-0.9-0.8
Intermitt. access day 15 inactive lever presses0.30.33.00.1-0.00.1-0.00.10.00.3-0.2-0.2-0.20.2-1.7
Intermitt. access escalation Index0.40.31.1-0.50.6-0.2-0.60.6-0.60.6-0.4-0.2-0.40.6-1.0
Intermittent access day 1 total infusions0.70.81.81.1-1.20.91.2-1.31.2-0.80.60.50.5-0.5-0.4
Intermittent access day 15 total infusions2.22.55.22.2-2.22.22.2-2.02.3-0.3-0.1-0.2-0.20.1-0.9
Intermittent access terminal intake (last 3 days)1.21.32.91.5-1.61.41.6-1.51.7-0.40.30.20.2-0.6-0.6
Intermittent access total infusions0.91.12.41.3-1.41.11.4-1.31.6-0.30.40.30.3-0.9-0.7
Intermittent access day 1 locomotion0.50.51.60.8-0.70.90.7-0.41.00.7-0.5-0.5-0.5-0.2-1.3
Intermittent access day 15 total locomotion0.91.02.21.3-1.41.21.4-1.41.5-0.40.20.20.2-0.4-0.6
Intermittent access total locomotion0.50.61.30.9-1.00.71.0-1.01.1-0.20.40.30.3-0.8-0.5
Intermittent access standard deviation0.10.10.90.0-0.2-0.20.2-0.20.3-0.00.30.40.4-1.0-0.3
Left kidney weight1.13.16.6-0.70.2-1.4-0.1-0.9-0.5-2.42.52.52.6-2.22.1
Right kidney weight0.82.24.0-1.00.6-1.5-0.6-0.3-0.9-1.82.01.92.0-1.62.0
Cocaine induced anxiety0.80.91.9-1.21.3-0.8-1.31.4-1.30.8-0.3-0.6-0.60.60.0
Post-drug Anxiety0.10.10.2-0.30.4-0.3-0.40.5-0.5-0.10.0-0.1-0.10.40.4
Baseline Anxiety1.31.43.11.6-1.71.31.8-1.61.6-1.10.30.30.3-0.1-0.1
Tail length3.19.318.6-2.01.2-3.1-1.1-0.9-1.7-3.64.24.34.3-3.63.3
Length with tail1.96.912.3-2.31.7-3.1-1.7-0.2-2.3-2.63.43.43.5-2.43.0
Length without tail0.10.31.4-0.40.5-0.1-0.50.4-0.70.5-0.4-0.6-0.41.20.2
Times rat made contact with spout0.70.81.8-1.31.3-1.0-1.20.8-1.3-0.00.60.60.6-0.50.7
Lifetime Intake1.11.22.91.4-1.51.21.6-1.41.7-0.40.30.30.2-0.9-0.8
Liver weight, left0.81.21.8-1.21.0-1.4-1.00.1-1.2-0.61.31.31.3-0.71.3
Liver weight, right3.66.012.1-3.22.9-3.5-2.91.6-3.0-0.42.12.12.2-2.01.8
Locomotor activity0.40.61.5-1.00.9-1.0-0.90.8-1.2-0.60.50.30.40.11.0
Locomotor testing distance0.71.23.7-0.2-0.1-0.70.1-0.6-0.3-1.91.61.61.6-1.11.2
Locomotor testing rearing1.82.85.4-1.40.9-2.0-0.9-0.0-1.2-1.92.32.32.3-1.91.2
Locomotion in novel chamber1.11.33.81.4-1.11.91.1-0.51.40.9-0.8-0.7-0.60.7-1.6
Locomotion in novel chamber post-restriction2.73.38.32.5-2.22.92.2-1.72.30.3-1.0-1.0-1.01.3-1.4
Fecal boli incidents, locomotor time 12.32.56.22.2-2.31.92.3-1.52.5-0.3-0.5-0.3-0.3-0.5-1.2
Change in fecal boli incidents, locomotor task1.61.53.2-1.51.7-1.1-1.71.6-1.80.8-0.5-0.7-0.71.20.4
Time >=10cm from walls, locomotor time 10.90.91.81.3-1.11.31.1-0.81.20.3-0.9-0.7-0.70.7-0.6
Bouts of movement, locomotor time 10.30.30.80.7-0.60.70.6-0.70.3-0.60.10.10.10.8-0.9
Total resting periods, locomotor time 10.50.51.70.8-0.61.00.6-0.50.4-0.1-0.3-0.5-0.51.3-1.2
Rest time, locomotor task time 10.60.71.51.0-0.81.20.8-0.30.70.2-0.7-0.8-0.81.2-0.7
Distance moved, locomotor task time 11.01.13.0-0.40.1-0.9-0.1-0.6-0.2-1.21.51.51.5-1.70.9
Vertical activity count, locomotor time 10.60.61.3-0.30.1-0.6-0.1-0.6-0.2-0.91.01.11.1-1.11.1
Time >=10cm from walls, locomotor time 20.70.71.60.9-1.00.51.0-1.21.0-0.80.50.60.6-0.80.4
Bouts of movement, locomotor time 20.20.21.0-0.1-0.0-0.30.0-0.3-0.1-0.50.70.50.5-0.3-1.0
Total resting periods, locomotor time 20.10.11.1-0.0-0.0-0.20.0-0.2-0.0-0.30.40.30.3-0.2-1.0
Rest time, locomotor task time 20.81.02.4-0.81.0-0.6-1.01.6-0.81.4-1.2-1.0-1.00.6-0.4
Distance moved, locomotor task time 22.02.34.20.9-1.30.31.3-2.01.2-1.82.01.71.7-2.00.8
Vertical activity count, locomotor time 21.61.83.60.4-0.8-0.10.8-1.50.6-1.71.91.61.6-1.91.2
Light reinforcement 10.91.63.5-1.81.8-1.9-1.71.6-1.60.60.10.10.0-0.50.1
Light reinforcement 20.20.20.6-0.30.4-0.2-0.40.6-0.20.7-0.4-0.4-0.4-0.1-0.8
Bone: marrow area0.81.83.70.6-1.00.21.0-1.60.8-1.91.81.81.8-1.60.7
Bone: maximum diameter1.12.04.71.2-1.50.71.5-2.21.2-1.91.61.41.4-0.90.2
Bone: maximum force0.50.81.81.2-1.11.41.1-1.01.10.1-0.4-0.4-0.40.7-0.9
Bone: maximum moment0.40.81.71.2-1.11.31.1-1.01.1-0.1-0.2-0.3-0.30.5-0.8
Mean time between licks in bursts2.43.37.30.5-1.1-0.21.1-1.90.9-2.42.62.52.5-2.70.8
Mean num. licks in bursts1.11.32.61.5-1.61.31.6-1.61.5-0.90.50.50.5-0.4-0.2
Cd content in liver0.30.40.7-0.80.7-0.8-0.60.4-0.7-0.20.50.50.5-0.50.7
Co content in liver1.11.32.70.8-1.10.21.1-1.50.9-1.61.41.31.3-1.30.2
Cu content in liver1.31.53.5-0.2-0.1-0.80.1-0.8-0.2-1.91.71.71.7-1.31.9
Fe content in liver0.40.51.20.8-1.00.31.0-0.91.1-0.40.40.30.3-0.9-0.4
K content in liver0.60.61.2-1.11.1-0.8-1.11.1-1.00.40.00.10.1-0.20.6
Mg content in liver0.00.00.40.0-0.00.10.0-0.1-0.0-0.20.20.20.2-0.10.6
Mn content in liver0.91.12.8-0.30.60.4-0.61.2-0.31.7-1.5-1.4-1.41.0-0.6
Na content in liver0.50.51.7-0.10.20.1-0.20.80.21.3-1.0-0.9-0.9-0.1-0.8
Rb content in liver0.50.71.90.4-0.60.20.6-1.10.2-1.41.00.90.90.11.2
Se content in liver1.31.64.0-1.21.4-0.7-1.42.0-1.01.8-1.2-1.3-1.30.30.1
Sr content in liver0.60.51.01.0-0.91.00.9-0.71.00.0-0.4-0.4-0.40.3-0.7
Zn content in liver1.11.22.50.9-1.10.31.1-1.50.9-1.61.21.21.2-1.00.8
Bone: minimum diameter1.12.04.6-0.1-0.3-0.60.4-1.10.1-2.02.22.12.1-1.90.9
Time in familiar zone, hab. session 10.00.00.10.2-0.20.30.2-0.30.3-0.00.00.10.0-0.1-0.1
Time in novel zone, hab. session 10.40.41.1-0.80.7-1.0-0.70.4-0.9-0.50.60.50.5-0.10.8
Total zone transitions, hab. session 10.81.23.8-0.20.50.4-0.60.9-0.61.2-1.3-1.5-1.51.9-0.8
Total locomotion distance, hab. session 14.05.612.6-3.43.2-3.5-3.12.6-3.00.41.11.11.1-1.71.0
Locomotion velocity, hab. session 13.44.810.6-3.12.9-3.3-2.92.5-2.70.50.90.90.9-1.70.8
Time in familiar zone, hab. session 20.40.51.10.5-0.60.50.6-1.00.3-1.00.80.70.7-0.20.6
Time in novel zone, hab. session 20.10.10.30.3-0.4-0.10.4-0.10.50.2-0.2-0.1-0.1-0.4-0.5
Total zone transitions, hab. session 20.40.52.60.20.10.4-0.10.3-0.20.5-0.9-1.0-1.01.6-0.6
Total locomotion distance, hab. session 22.73.68.2-2.62.4-2.9-2.41.8-2.4-0.31.31.21.2-1.41.2
Locomotion velocity, hab. session 23.14.19.2-2.82.5-3.0-2.51.8-2.6-0.41.41.41.3-1.41.3
Novel to familiar place preference ratio0.10.10.2-0.20.3-0.4-0.30.3-0.30.3-0.1-0.1-0.00.2-0.5
Novelty place preference0.00.00.2-0.10.1-0.3-0.10.1-0.10.10.00.10.10.1-0.4
Time in novel zone, NPP test0.00.00.30.2-0.2-0.00.2-0.20.1-0.10.00.10.10.3-0.5
Total zone transitions, NPP test0.60.92.00.9-0.71.20.7-0.20.70.5-1.1-1.2-1.21.4-1.0
Total locomotion distance, NPP test1.72.35.8-2.01.7-2.4-1.71.5-1.5-0.11.11.11.0-2.10.4
Locomotion velocity, NPP test2.13.07.4-2.32.0-2.7-2.01.8-1.80.21.01.01.0-2.20.5
Intraocular pressure3.24.59.23.0-2.83.02.8-2.42.7-0.4-0.7-0.7-0.71.1-2.0
Delta distance traveled before/after self-admin0.50.51.2-0.60.8-0.2-0.80.8-0.80.7-0.8-0.8-0.71.10.1
Delta ambulatory time before/after self-admin0.80.93.3-0.20.50.3-0.50.8-0.61.0-1.3-1.2-1.21.8-0.1
Parametrial fat weight1.22.44.9-2.12.0-2.1-2.01.2-2.2-0.30.91.01.0-0.41.6
Pavlov. Cond. lever latency0.50.71.3-1.01.1-0.7-1.11.2-1.10.8-0.6-0.4-0.40.6-0.1
Pavlov. Cond. magazine entry latency0.91.22.30.9-1.10.31.1-1.50.9-1.51.31.01.0-1.00.7
Pavlov. Cond. change in total contacts1.11.22.31.2-1.40.71.4-1.51.5-0.80.80.70.7-1.30.0
Pavlov. Cond. index score1.31.62.91.1-1.40.51.4-1.71.2-1.71.41.21.2-1.30.6
Pavlov. Cond. latency score1.11.42.71.0-1.30.51.3-1.61.2-1.51.31.11.2-1.30.4
Pavlov. Cond. lever contacts0.70.91.50.8-1.10.51.1-1.21.0-1.11.00.80.8-1.00.3
Pavlov. Cond. magazine entry number1.11.42.9-1.11.4-0.5-1.41.7-1.11.6-1.2-1.0-1.00.8-0.8
Pavlov. Cond. intertrial magazine entries0.50.61.4-1.01.0-0.9-1.01.2-0.90.6-0.1-0.2-0.2-0.30.2
Pavlov. Cond. lever-magazine prob. diff.1.01.32.41.0-1.30.51.3-1.61.2-1.41.21.01.0-1.10.6
Pavlov. Cond. response bias0.50.61.20.5-0.70.10.7-0.90.6-1.11.00.80.8-0.90.8
Pavlov. Cond. lever latency6.89.120.3-3.94.2-3.2-4.24.5-3.53.2-1.3-1.2-1.2-0.3-0.4
Pavlov. Cond. magazine entry latency3.43.98.22.9-2.82.62.8-2.52.5-1.1-0.3-0.3-0.31.1-0.4
Pavlov. Cond. change in total contacts4.15.713.23.0-3.32.53.3-3.62.8-2.61.11.11.10.00.4
Pavlov. Cond. index score6.17.816.93.7-3.93.23.9-4.13.4-2.70.90.90.90.30.1
Pavlov. Cond. latency score5.77.114.83.7-3.83.23.8-3.93.3-2.40.70.60.60.6-0.0
Pavlov. Cond. lever contacts6.08.218.83.7-3.93.03.9-4.33.2-3.21.41.31.40.30.6
Pavlov. Cond. magazine entry number7.18.718.0-4.14.2-3.7-4.24.1-3.92.1-0.3-0.3-0.3-0.60.5
Pavlov. Cond. intertrial magazine entries2.33.06.2-2.01.7-2.5-1.60.9-1.7-1.01.81.81.7-2.11.3
Pavlov. Cond. lever-magazine prob. diff.5.77.316.13.6-3.83.03.8-4.03.3-2.71.01.01.00.20.2
Pavlov. Cond. response bias7.29.721.54.1-4.43.34.4-4.63.8-3.21.31.31.30.00.2
Time in closed arm before self-admin0.91.02.40.7-0.51.00.40.10.71.0-1.4-1.3-1.31.0-1.5
Time in closed arm after self-admin1.71.73.61.2-0.91.80.8-0.10.90.9-1.6-1.6-1.61.9-1.2
Time in open arm before self-admin0.70.81.6-1.21.2-1.2-1.21.2-1.30.20.10.10.10.10.7
Time in open arm after self-admin0.91.02.3-0.80.5-1.1-0.5-0.1-0.6-0.91.31.51.5-1.30.9
Bone: periosteal estimation1.32.85.21.2-1.60.51.6-2.31.4-2.22.01.91.9-1.80.3
Bone: periosteal perimeter0.91.53.90.8-1.00.51.0-1.70.6-2.01.61.51.6-0.50.8
Bone: post-yield work0.20.20.80.3-0.20.90.10.10.20.5-0.5-0.5-0.50.6-0.5
Progressive ratio test 1 active lever presses0.10.10.40.00.10.3-0.10.30.10.6-0.4-0.5-0.50.1-0.4
Progressive ratio test 1 breakpoint0.10.10.5-0.00.10.2-0.10.40.10.7-0.5-0.5-0.6-0.0-0.5
Progressive ratio test 1 inactive lever presses0.10.10.80.2-0.2-0.00.2-0.10.3-0.00.00.20.1-0.5-0.9
Progressive ratio test 2 active lever presses1.71.83.61.3-1.60.71.6-1.91.6-1.31.21.31.1-1.60.0
Progressive ratio test 2 breakpoint1.31.42.61.0-1.30.51.3-1.61.3-1.11.21.31.1-1.60.1
Progressive ratio test 2 inactive lever presses0.60.71.30.9-1.10.61.1-1.11.2-0.60.60.60.4-1.0-0.7
Incentive Sensitization - Responses2.12.14.21.2-1.50.51.5-2.01.4-1.61.51.71.5-1.70.2
Incentive Sensitization - Breakpoint1.91.93.91.2-1.50.51.5-2.01.5-1.51.41.61.4-1.60.0
Sum of active levers in priming session hrs 5-60.30.30.8-0.80.7-0.9-0.70.4-0.80.00.10.40.4-0.10.6
Progressive ratio1.21.43.31.5-1.41.81.4-0.71.30.0-0.8-0.8-0.81.1-1.2
Food seeking constrained by brief footshock0.60.82.5-0.1-0.2-0.60.2-0.5-0.2-1.61.31.31.3-0.90.7
Seeking ratio, punishment vs. effort2.12.65.5-1.61.2-2.3-1.20.3-1.2-1.01.81.81.8-2.21.7
Retroperitoneal fat weight4.916.230.6-4.73.9-5.5-3.91.4-4.4-2.44.34.14.3-3.44.4
Reaction time number correct0.81.12.2-0.40.7-0.2-0.81.3-0.71.2-1.4-1.4-1.41.5-0.4
Reaction time mean minus median0.30.41.2-0.0-0.1-0.20.1-0.5-0.1-1.11.00.91.0-0.30.6
Reaction time mean minus median AUC0.10.10.40.2-0.20.20.2-0.40.0-0.60.50.40.60.10.2
Reaction time num false alarms0.40.51.0-1.01.0-1.0-1.00.7-1.00.00.30.20.3-0.20.5
Reaction time num false alarms AUC0.00.10.1-0.30.3-0.2-0.30.4-0.30.2-0.0-0.2-0.1-0.1-0.1
Reaction time trials correct on left0.81.12.2-0.40.7-0.2-0.81.3-0.71.2-1.4-1.4-1.41.5-0.4
Reaction time trials on left0.81.12.1-0.40.7-0.2-0.71.3-0.71.2-1.4-1.4-1.41.5-0.5
Reaction time mean0.20.30.9-0.70.7-0.9-0.70.5-0.7-0.10.40.30.2-0.40.0
Reaction time mean AUC0.10.20.5-0.60.6-0.7-0.60.5-0.50.20.1-0.0-0.0-0.1-0.1
Median of all reaction times0.20.20.6-0.60.6-0.8-0.60.7-0.50.4-0.1-0.2-0.3-0.3-0.4
Reaction time omissions0.20.30.8-0.1-0.1-0.50.1-0.3-0.1-0.90.80.70.8-0.40.2
Reaction time false alarm rate0.10.10.6-0.1-0.0-0.10.1-0.30.1-0.20.50.40.5-0.7-0.0
Reaction time premature initiation rate2.53.36.3-1.20.7-2.0-0.7-0.4-1.0-2.02.52.42.5-2.32.1
Reaction time premature initiations1.11.63.0-1.10.8-1.7-0.80.2-1.0-1.31.51.41.5-1.41.6
Std. dev. reaction times0.60.92.1-0.40.1-0.8-0.1-0.4-0.4-1.41.41.41.4-0.91.0
Reaction time trials completed0.81.12.1-0.40.7-0.2-0.71.3-0.71.2-1.4-1.4-1.41.5-0.5
Reaction time trials AUC0.60.91.6-0.50.8-0.4-0.81.2-0.81.0-1.1-1.2-1.21.3-0.3
Run reversals in cocaine runway, females2.92.85.7-0.90.5-1.6-0.4-0.4-0.9-2.22.32.42.4-1.62.0
Run reversals in cocaine runway, males1.31.22.61.5-1.31.61.3-1.11.2-0.1-0.7-0.6-0.71.3-0.8
Latency to leave start box in cocaine runway0.90.91.9-1.31.3-1.4-1.31.4-1.00.8-0.2-0.3-0.2-0.70.6
Latency to leave start box in cocaine runway, F0.70.72.4-1.10.9-1.3-0.90.8-0.60.10.50.40.4-1.60.6
Latency to leave start box in cocaine runway, M0.90.92.1-0.60.8-0.3-0.81.2-0.61.4-1.2-1.2-1.10.8-0.4
Std. dev. time between licks in bursts1.51.83.3-1.10.7-1.4-0.70.1-0.9-1.41.81.71.7-1.81.5
Total sessions with >9 infusions0.70.82.01.2-1.21.11.2-0.71.40.0-0.1-0.2-0.3-0.4-1.0
Short access day 1 total inactive lever presses0.20.30.60.7-0.70.60.7-0.50.7-0.10.10.00.1-0.1-0.8
Short access day 10 total inactive lever presses0.90.92.0-1.31.4-1.2-1.41.2-1.40.6-0.1-0.10.00.3-0.2
Short access day 1 total infusions0.91.02.11.1-1.30.71.3-1.11.4-0.60.50.60.4-1.2-0.5
Short access day 10 total infusions1.01.12.31.2-1.40.91.4-1.31.5-0.80.60.60.5-1.2-0.4
Short access total infusions0.60.71.50.9-1.10.61.1-0.81.2-0.40.40.40.3-1.2-0.8
Short access day 1 locomotion1.82.04.12.0-1.81.91.8-1.02.00.3-0.8-0.9-0.90.5-1.1
Short access day 10 total locomotion0.10.10.20.3-0.40.10.4-0.40.4-0.20.40.30.4-0.5-0.3
Short access total locomotion0.20.21.00.2-0.10.10.10.40.50.7-0.3-0.4-0.4-0.6-1.0
One hour access (0.3 mA shock)1.61.83.21.3-1.60.71.6-1.81.6-1.41.31.11.2-1.50.4
Compulsive drug intake0.00.00.1-0.10.1-0.2-0.10.30.10.2-0.10.00.0-0.4-0.3
One hour access (shock baseline)0.80.91.81.2-1.30.91.3-1.41.3-0.80.70.40.5-0.60.2
Social response proportion1.51.63.2-1.81.8-1.7-1.81.7-1.60.70.20.00.1-0.60.8
Social responses1.62.14.3-1.91.7-2.1-1.71.2-1.9-0.51.11.01.0-0.81.3
Social time1.11.53.5-1.51.6-1.3-1.61.9-1.41.1-0.6-0.6-0.60.00.4
Soleus weight0.82.54.4-1.51.1-1.9-1.10.0-1.5-1.62.11.91.9-1.41.9
Bone: stiffness0.10.10.30.2-0.10.40.1-0.20.10.3-0.3-0.3-0.30.6-0.2
Tibialis anterior weight0.10.50.9-0.80.6-0.9-0.60.0-0.9-0.70.90.80.9-0.30.4
Time to tail flick, vehicle, before self-admin0.50.51.4-0.90.9-1.2-0.90.5-1.0-0.10.20.10.2-0.10.8
Time to tail flick, vehicle, after self-admin1.01.12.41.5-1.41.51.4-1.31.3-0.5-0.5-0.3-0.30.8-0.2
Time to tail flick, test, before self-admin0.40.41.00.8-0.90.70.9-1.00.8-0.70.40.20.3-0.10.1
Time to tail flick, test, after self-admin0.90.92.20.8-1.00.31.0-1.30.7-1.50.90.91.0-0.70.8
Delta time to tail flick, vehicle, before/after SA2.32.25.32.1-1.92.31.9-1.32.00.1-0.9-0.8-0.80.9-1.1
Delta time to tail flick, test, before/after SA0.10.10.2-0.40.4-0.3-0.40.5-0.40.2-0.3-0.1-0.10.10.1
Tibia length0.51.32.81.6-1.61.41.6-1.11.7-0.0-0.5-0.5-0.50.1-1.3
Ambulatory time before self-admin0.10.10.20.3-0.20.30.20.10.20.4-0.4-0.3-0.30.4-0.3
Ambulatory time after self-admin1.11.23.2-0.30.70.2-0.71.1-0.61.5-1.6-1.4-1.41.8-0.3
Bone: tissue strength1.91.94.9-0.40.80.2-0.81.3-0.52.2-1.8-1.8-1.81.6-1.3
Total heroin consumption0.10.10.80.2-0.10.20.1-0.10.00.0-0.30.00.00.60.9
Bone: trabecular number0.40.61.40.10.20.7-0.20.6-0.01.2-1.1-1.1-1.11.1-0.6
Bone: trabecular spacing0.20.30.70.7-0.80.30.8-0.60.8-0.40.10.10.1-0.6-0.3
Bone: trabecular thickness0.40.41.8-0.40.3-0.3-0.3-0.2-0.7-0.90.70.70.70.51.3
Bone: trabecular tissue density1.92.65.8-2.22.1-2.1-2.11.3-2.4-0.40.91.01.0-0.11.6
Water consumed over 24 hours0.80.91.9-1.21.3-0.7-1.31.4-1.31.0-0.6-0.6-0.60.60.1
Number of responses in last shaping day1.21.26.0-0.70.3-1.4-0.30.1-0.1-0.81.31.41.4-2.50.2