Hub : Genes

Kcnj16

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA alternative polyA NM_053314.3 0.04 0.02 1.8e-04 0.04 0.05 0.04 0.04 1.7e-04 1.1e-04 6.4e-04 2.2e-04
2 pVTA alternative polyA XM_006247570.4 0.04 0.02 9.1e-05 0.04 0.05 0.04 0.04 2.5e-04 7.0e-05 8.3e-04 2.4e-04
3 pVTA isoform ratio NM_053314.3 0.16 0.06 0.0e+00 0.21 0.22 0.2 0.22 4.5e-17 2.7e-17 3.0e-16 7.0e-18
4 pVTA gene expression Kcnj16 0.27 0.08 0.0e+00 0.41 0.43 0.44 0.44 8.5e-35 6.4e-38 1.9e-38 1.4e-38
5 pVTA isoform ratio XM_006247570.4 0.16 0.06 0.0e+00 0.22 0.22 0.2 0.22 3.7e-17 2.7e-17 2.2e-16 5.5e-18
6 Brain isoform ratio XM_006247570.4 0.04 0.02 2.5e-05 0.04 0.04 0.03 0.04 1.5e-04 5.1e-05 6.8e-04 6.7e-05
7 Brain alternative TSS NM_053314.3 0.25 0.08 0.0e+00 0.33 0.29 0.31 0.32 3.5e-31 2.6e-27 4.9e-29 6.1e-30
8 Brain alternative TSS XM_006247570.4 0.25 0.08 0.0e+00 0.32 0.29 0.31 0.31 4.8e-31 2.9e-27 5.3e-29 7.8e-30
9 NAcc alternative TSS NM_053314.3 0.02 0.02 9.7e-03 -0 0 0.01 0 7.5e-01 4.9e-02 4.0e-02 2.3e-01
10 PL gene expression Kcnj16 0.04 0.02 1.5e-05 0.03 0.02 0.03 0.03 3.1e-04 1.4e-03 6.2e-04 8.7e-04
11 Brain isoform ratio NM_053314.3 0.04 0.02 1.9e-05 0.04 0.05 0.05 0.04 1.2e-04 3.7e-05 2.0e-05 5.5e-05
12 LHb gene expression Kcnj16 0.48 0.13 4.7e-12 0.33 0.44 0.33 0.42 9.4e-09 7.3e-12 1.2e-08 3.9e-11
13 Brain gene expression Kcnj16 0.24 0.07 0.0e+00 0.4 0.4 0.41 0.41 3.2e-40 5.5e-40 2.4e-40 3.8e-41
14 Liver alternative polyA NM_053314.3 0.03 0.02 7.0e-03 0.02 0.01 0.01 0.02 2.5e-03 3.4e-02 3.0e-02 5.4e-03
15 Liver alternative polyA XM_006247570.4 0.03 0.02 8.7e-03 0.02 0.01 0.01 0.02 2.7e-03 4.9e-02 1.6e-02 6.1e-03
16 pVTA alternative TSS NM_053314.3 0.33 0.08 0.0e+00 0.39 0.37 0.38 0.38 2.2e-33 9.7e-31 9.2e-32 7.3e-32
17 pVTA alternative TSS XM_006247570.4 0.33 0.08 0.0e+00 0.4 0.37 0.38 0.38 5.3e-34 4.0e-31 2.4e-32 2.2e-32
18 IC gene expression Kcnj16 0.12 0.06 2.8e-05 0.11 0.12 0.1 0.12 1.8e-05 1.2e-05 3.6e-05 1.2e-05
19 BLA gene expression Kcnj16 0.11 0.06 1.6e-03 0.03 0.05 0.03 0.04 1.3e-02 1.1e-03 1.3e-02 3.7e-03
20 NAcc gene expression Kcnj16 0.04 0.02 9.9e-03 0 0.01 -0 0 2.4e-01 1.6e-02 4.3e-01 8.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density4.68.510.43.0-3.13.03.1-3.1-2.8-3.03.0-3.2-2.9-3.03.23.2-3.13.1-3.13.12.81.01.5
Area under the delay curve0.10.22.5-0.0-0.00.20.3-0.3-0.4-0.20.2-0.5-0.1-0.40.40.3-0.40.4-0.20.2-0.2-0.7-1.6
BMI with tail1.96.69.6-2.32.5-2.8-2.62.82.52.6-2.62.82.32.4-3.1-2.63.1-3.13.0-3.0-2.1-1.0-1.3
BMI without tail2.010.917.0-3.03.2-3.2-3.33.33.43.4-3.43.23.43.5-4.1-3.73.6-3.63.5-3.5-3.2-0.7-2.2
Body weight1.25.210.5-1.92.1-2.2-2.32.22.32.2-2.22.12.22.6-3.2-2.62.5-2.52.4-2.4-2.1-0.6-2.4
Weight adjusted by age1.03.05.6-1.61.7-1.9-1.71.91.71.9-1.92.41.81.4-2.0-1.52.0-2.02.0-2.0-1.1-0.20.3
Bone surface12.023.728.45.3-5.35.35.2-5.3-5.0-5.15.1-4.9-5.0-5.14.85.0-5.15.1-5.05.04.72.51.6
Bone volume8.717.220.64.5-4.54.54.5-4.5-4.4-4.54.5-4.3-4.3-4.34.44.5-4.24.2-4.24.24.01.50.9
Breakpoint value in progressive ratio session0.51.01.81.0-1.00.90.8-0.9-0.9-1.01.0-0.6-1.4-1.10.70.9-1.11.1-1.21.21.20.41.0
Number of licking bursts0.20.61.10.8-0.80.60.8-0.7-0.7-0.90.9-0.6-0.9-0.80.51.0-0.70.7-0.70.71.00.60.7
Context. condit. distance diff. score1.11.32.1-1.11.1-1.1-1.11.11.21.0-1.01.01.01.3-1.0-1.41.3-1.31.4-1.4-1.5-0.8-0.7
Locomotion velocity, session 10.10.10.50.4-0.40.20.7-0.2-0.3-0.20.2-0.0-0.4-0.40.20.3-0.20.2-0.30.30.70.10.5
Locomotion distance, session 10.91.24.5-1.21.1-1.2-0.91.20.81.0-1.01.30.90.7-0.7-0.61.0-1.00.9-0.9-1.1-2.1-1.0
Locomotion velocity, session 20.10.20.50.3-0.30.40.3-0.4-0.0-0.40.4-0.0-0.40.10.10.0-0.70.7-0.70.70.50.30.5
Locomotion distance, session 20.10.11.9-0.0-0.0-0.10.10.1-0.2-0.30.30.5-0.3-0.10.30.3-0.10.1-0.30.30.1-1.4-0.3
Locomotion velocity, session 31.21.33.5-1.21.2-1.3-1.31.30.91.2-1.21.91.01.0-1.0-1.01.1-1.11.2-1.2-0.8-1.0-0.6
Locomotion distance, session 30.00.00.20.1-0.10.00.3-0.0-0.30.0-0.00.2-0.3-0.40.40.30.0-0.0-0.00.00.3-0.30.0
Stereotopy head waving bouts, day 30.10.10.7-0.30.2-0.3-0.50.30.00.2-0.20.80.20.3-0.0-0.20.4-0.40.3-0.3-0.5-0.8-0.3
Stereotopy head waving duration, day 30.00.10.40.2-0.20.3-0.1-0.2-0.1-0.10.10.2-0.00.1-0.0-0.1-0.20.2-0.20.20.10.60.6
Locomotion velocity, session 71.01.11.71.1-1.21.31.1-1.2-1.1-0.90.9-0.8-0.9-1.01.11.0-1.31.3-1.21.20.90.4-0.0
Locomotion distance, session 70.60.81.50.9-1.00.90.7-0.9-1.1-0.90.9-0.4-1.2-0.80.90.9-0.90.9-0.80.8-0.1-1.1-1.2
Stereotopy head waving bouts, day 70.70.88.20.3-0.20.30.5-0.30.20.1-0.1-0.60.2-0.2-0.00.0-0.30.3-0.30.31.32.22.9
Stereotopy head waving duration, day 71.11.412.20.6-0.60.70.7-0.7-0.1-0.30.3-0.7-0.2-0.60.30.4-0.80.8-0.80.81.92.63.5
Locomotion velocity, session 80.10.20.60.6-0.50.40.5-0.4-0.5-0.40.40.3-0.6-0.20.30.1-0.30.3-0.30.30.1-0.4-0.8
Locomotion distance, session 80.60.82.5-0.90.9-0.8-0.80.90.80.5-0.51.10.51.1-0.7-1.00.8-0.80.9-0.9-1.2-1.6-1.0
Degree of sensitization distance0.40.52.30.6-0.60.70.3-0.7-0.6-0.60.6-0.3-0.6-0.20.40.4-0.70.7-0.60.6-0.6-1.0-1.5
Degree of sensitization stereotypy0.91.09.3-0.30.3-0.20.10.20.90.7-0.7-0.20.70.2-0.7-0.50.2-0.20.2-0.21.02.33.0
Conditioned locomotion0.30.40.9-0.40.4-0.7-0.40.70.10.5-0.50.60.3-0.1-0.00.11.0-1.00.9-0.9-0.5-0.8-0.4
Cocaine response after cond. corrected0.10.10.40.2-0.2-0.00.50.0-0.4-0.10.1-0.3-0.1-0.70.40.50.2-0.20.2-0.20.3-0.5-0.6
Cocaine response after cond. not corrected0.10.10.40.4-0.40.20.6-0.2-0.4-0.10.1-0.5-0.1-0.50.30.50.1-0.10.1-0.10.40.1-0.2
Cocaine response before conditioning0.10.10.9-0.00.10.0-0.20.00.40.4-0.40.00.40.5-0.5-0.10.1-0.10.1-0.1-0.30.90.6
Saline control response3.54.89.0-2.22.1-2.3-2.42.31.51.8-1.82.61.61.8-1.7-1.82.1-2.12.1-2.1-2.8-3.0-3.0
Bone: connectivity density5.89.211.73.1-3.23.03.1-3.1-3.1-3.23.2-2.8-3.2-3.43.23.4-3.23.2-3.23.23.11.11.9
Bone: cortical apparent density4.26.78.8-3.02.9-2.9-2.72.92.82.4-2.42.72.52.6-2.5-2.82.4-2.42.4-2.4-2.7-2.7-1.1
Bone: cortical area0.30.43.9-0.10.1-0.3-0.00.3-0.3-0.30.30.3-0.2-0.10.10.20.4-0.40.4-0.4-0.7-2.0-1.7
Bone: cortical porosity2.52.75.81.7-1.72.02.0-2.0-1.0-1.51.5-2.4-1.1-0.91.11.1-1.71.7-1.61.61.62.31.1
Bone: cortical porosity1.61.83.91.5-1.41.61.7-1.6-1.0-1.21.2-1.9-0.9-0.90.91.0-1.31.3-1.21.21.42.00.6
Bone: cortical thickness13.322.227.9-5.35.2-5.2-5.05.14.84.6-4.64.64.84.7-4.4-4.44.7-4.74.7-4.7-5.0-4.5-2.6
Bone: cortical thickness3.54.25.8-2.32.3-2.4-2.12.41.81.8-1.82.41.71.7-1.6-1.62.2-2.22.3-2.3-2.3-2.3-1.1
Bone: cortical tissue density4.06.38.4-2.92.8-2.8-2.62.82.72.4-2.42.72.42.5-2.4-2.72.4-2.42.3-2.3-2.6-2.6-1.0
Condit. Reinf. active minus inactive responses0.60.71.1-0.70.8-0.9-0.60.90.90.8-0.80.40.70.7-1.0-0.81.0-1.01.0-1.0-0.50.30.8
Condit. Reinf. active-inactive response ratio0.10.11.40.3-0.20.20.3-0.20.0-0.10.1-0.5-0.2-0.10.00.1-0.00.0-0.10.10.40.71.2
Condit. Reinf. active responses0.91.21.9-1.01.1-1.2-0.91.21.21.2-1.20.61.00.9-1.2-1.01.4-1.41.4-1.4-0.80.10.6
Condit. Reinf. inactive responses0.60.81.3-0.90.9-1.0-0.81.00.80.9-0.90.70.80.6-0.8-0.71.1-1.11.1-1.1-0.9-0.7-0.4
Incentive salience index mean0.30.41.7-0.50.5-0.7-0.40.70.70.6-0.60.30.50.3-0.6-0.40.7-0.70.7-0.7-0.00.41.3
Condit. Reinf. lever presses0.40.61.0-0.90.8-0.9-0.70.90.91.0-1.00.70.90.6-0.7-0.60.8-0.80.7-0.7-0.30.00.9
Condit. Reinf. active minus inactive responses0.10.21.50.4-0.40.40.5-0.40.1-0.20.2-0.8-0.1-0.1-0.10.1-0.00.0-0.00.00.41.21.0
Condit. Reinf. active-inactive response ratio0.20.31.5-0.10.2-0.1-0.10.10.60.5-0.5-0.60.60.5-0.6-0.50.4-0.40.5-0.5-0.11.21.1
Condit. Reinf. active responses0.20.30.70.7-0.70.70.7-0.7-0.5-0.60.6-0.8-0.6-0.60.50.5-0.40.4-0.40.40.20.10.0
Condit. Reinf. inactive responses0.30.41.10.6-0.60.60.5-0.6-0.7-0.70.7-0.0-0.7-0.80.70.7-0.50.5-0.60.60.0-1.0-0.7
Condit. Reinf. lever presses0.20.20.50.4-0.40.70.5-0.6-0.2-0.70.7-0.7-0.3-0.10.2-0.2-0.40.4-0.40.4-0.3-0.4-0.7
Condit. Reinf. lever reinforcers received0.20.20.50.6-0.60.60.6-0.6-0.4-0.70.7-0.7-0.6-0.40.40.3-0.30.3-0.30.3-0.0-0.2-0.4
Conditioned reinforcement - actives0.31.01.71.1-1.11.21.3-1.2-0.9-1.11.1-1.1-1.1-0.60.90.6-1.01.0-1.21.20.70.90.2
Conditioned reinforcement - inactives0.10.10.70.1-0.10.2-0.0-0.20.1-0.40.4-0.1-0.20.4-0.1-0.4-0.20.2-0.30.3-0.6-0.8-0.8
Conditioned locomotion0.10.10.5-0.10.1-0.1-0.10.10.20.1-0.10.00.20.4-0.4-0.40.2-0.20.1-0.1-0.5-0.2-0.7
Patch foraging indifference point 0 sec1.23.38.3-1.71.6-1.5-1.71.51.71.3-1.31.41.72.1-1.8-2.21.5-1.51.4-1.4-2.6-2.2-2.9
Patch foraging indifference point AUC0.51.11.6-1.21.1-1.1-1.31.21.01.0-1.01.11.01.2-1.0-1.01.1-1.11.0-1.0-0.9-0.5-0.6
Delay disc. indifference point, 0s delay0.20.20.4-0.60.6-0.5-0.40.50.50.6-0.60.30.60.3-0.4-0.30.4-0.40.5-0.5-0.6-0.5-0.3
Delay disc. indifference point, 16s delay0.60.82.40.8-0.81.01.1-1.0-0.8-0.60.6-1.5-0.6-1.00.91.1-1.01.0-0.80.80.90.80.1
Delay disc. indifference point, 2s delay0.40.55.0-0.0-0.10.20.1-0.2-0.4-0.40.4-0.1-0.3-0.30.50.2-0.50.5-0.30.3-0.5-1.7-2.2
Delay disc. indifference point, 24s delay1.01.63.91.2-1.21.31.5-1.3-1.1-1.11.1-2.0-0.9-1.31.21.2-1.11.1-0.90.91.51.60.7
Delay disc. indifference point, 4s delay0.50.63.3-0.80.7-0.6-0.60.60.30.6-0.60.80.50.4-0.4-0.40.3-0.30.6-0.6-0.9-1.4-1.8
Delay disc. indifference point, 8s delay0.20.42.0-0.80.7-0.6-0.50.60.40.5-0.50.60.40.4-0.3-0.40.4-0.40.4-0.4-0.7-0.7-1.4
Indifference point function ln k0.00.00.40.1-0.10.10.2-0.10.10.1-0.1-0.40.1-0.0-0.00.0-0.00.00.0-0.0-0.2-0.00.7
Indifference point function log k0.00.00.40.1-0.10.10.2-0.10.10.1-0.1-0.40.1-0.0-0.00.0-0.00.00.0-0.0-0.2-0.00.7
Patch foraging total patch changes 0 sec1.33.79.7-1.81.8-1.7-1.81.71.71.4-1.41.61.72.1-1.8-2.21.6-1.61.6-1.6-2.8-2.6-3.1
Patch foraging total patch changes 12 sec2.02.76.2-1.61.6-1.6-1.51.61.31.3-1.31.61.41.7-1.3-1.61.6-1.61.6-1.6-1.9-2.1-2.5
Patch foraging total patch changes 18 sec2.04.86.3-2.42.4-2.3-2.52.32.42.0-2.02.02.22.5-2.3-2.42.2-2.22.2-2.2-2.3-1.5-1.4
Patch foraging total patch changes 24 sec0.31.03.2-0.80.8-0.8-0.80.90.70.6-0.60.70.71.1-0.8-1.01.0-1.00.9-0.9-1.3-1.5-1.8
Patch foraging total patch changes 6 sec3.45.88.8-2.62.6-2.4-2.72.42.82.2-2.22.02.53.0-2.9-2.92.2-2.22.2-2.2-2.6-1.0-1.6
Patch foraging time to switch 0 sec0.62.12.81.6-1.61.61.5-1.6-1.5-1.31.3-1.3-1.4-1.71.41.5-1.51.5-1.41.41.61.30.9
Patch foraging water rate 0 sec1.55.87.2-2.62.6-2.7-2.42.72.62.3-2.32.12.42.4-2.6-2.42.6-2.62.6-2.6-2.4-1.8-0.9
Patch foraging water rate 12 sec0.72.75.3-1.71.7-1.8-1.71.81.61.3-1.31.71.41.7-1.8-1.61.5-1.51.4-1.4-2.0-2.3-1.3
Patch foraging water rate 18 sec0.81.92.3-1.41.4-1.5-1.41.51.51.5-1.51.11.31.5-1.3-1.31.5-1.51.4-1.4-1.4-1.00.3
Patch foraging water rate 24 sec0.30.41.0-0.80.8-0.5-0.60.50.70.3-0.3-0.10.50.8-0.4-0.70.5-0.50.6-0.6-0.9-1.0-0.5
Patch foraging water rate 6 sec1.52.23.2-1.61.5-1.7-1.31.71.51.6-1.61.11.61.1-1.3-1.11.7-1.71.7-1.7-1.5-1.8-0.1
Seeking ratio, delayed vs. immediate footshock1.62.34.1-1.41.5-1.6-1.51.61.61.7-1.71.22.01.6-1.9-1.61.7-1.71.6-1.6-1.10.8-0.3
Distance traveled before self-admin0.81.72.6-1.31.3-1.3-1.21.31.51.6-1.60.91.61.3-1.3-1.31.5-1.51.5-1.5-1.20.00.3
Distance traveled after self-admin0.91.62.8-1.11.1-1.2-1.21.31.21.7-1.70.91.61.1-1.2-0.91.6-1.61.6-1.6-0.80.10.7
Extensor digitorum longus weight0.00.10.70.10.0-0.0-0.30.00.00.3-0.30.60.1-0.0-0.5-0.2-0.10.1-0.10.10.10.8-0.2
Bone: elastic displacement3.84.87.0-2.62.6-2.5-2.42.52.62.4-2.41.92.32.3-2.1-2.12.2-2.22.2-2.2-1.9-0.70.6
Bone: elastic work0.81.11.9-1.41.3-1.3-1.21.21.30.8-0.80.80.81.0-1.0-0.91.0-1.00.9-0.9-1.1-1.20.1
Bone: endosteal estimation15.738.452.97.3-7.16.96.9-6.8-6.9-6.76.7-6.1-6.8-6.55.96.2-5.95.9-5.95.95.73.60.7
Bone: endosteal perimeter14.134.647.46.9-6.76.56.6-6.4-6.6-6.46.4-5.8-6.4-6.35.66.1-5.65.6-5.75.75.42.90.5
Epididymis fat weight1.47.18.8-2.82.8-2.9-2.62.82.72.7-2.72.12.72.8-3.0-2.52.8-2.82.8-2.8-2.8-1.9-2.3
Delta time in closed arm before/after self-admin0.10.10.20.2-0.20.30.4-0.3-0.1-0.10.1-0.4-0.1-0.20.30.2-0.10.1-0.10.10.30.40.4
Delta time in open arm before/after self-admin0.50.61.30.9-0.90.90.9-0.8-1.1-0.80.8-0.4-0.8-0.91.20.8-0.70.7-0.80.80.4-0.5-0.5
Diff in mean of infusions in LGA sessions0.81.52.4-1.41.4-1.3-1.51.21.41.1-1.11.40.91.4-1.5-1.40.8-0.81.0-1.0-1.5-1.2-0.8
Delay discount exponential model param0.20.32.9-0.00.1-0.2-0.40.30.40.2-0.20.50.10.4-0.4-0.30.4-0.40.2-0.20.30.81.7
Extinction: sum of active levers before priming2.03.16.01.9-1.91.92.0-1.9-1.4-1.41.4-2.3-1.4-1.61.21.7-1.51.5-1.41.42.02.42.2
Active lever presses in extinction session 63.93.95.32.0-2.02.11.8-2.1-2.2-2.12.1-1.9-2.2-2.02.22.0-2.32.3-2.12.10.9-0.9-1.0
Bone: final force1.11.82.71.5-1.51.41.6-1.3-1.6-1.61.6-1.2-1.6-1.41.51.4-1.11.1-1.11.10.9-0.5-0.8
Bone: final moment0.81.21.91.3-1.31.31.4-1.2-1.3-1.31.3-1.2-1.3-1.11.21.1-0.90.9-0.90.90.6-0.3-0.8
Food consumed during 24 hour testing period0.10.30.90.3-0.40.40.2-0.4-0.5-0.70.70.1-0.4-0.40.40.4-0.60.6-0.60.60.2-0.9-0.6
Glucose0.20.32.5-0.20.2-0.5-0.20.4-0.2-0.30.30.4-0.40.10.10.00.4-0.40.4-0.4-0.4-1.6-1.4
Heart weight1.62.73.6-1.71.8-1.7-1.61.71.91.6-1.60.91.91.6-1.9-1.81.8-1.81.8-1.8-1.5-0.7-0.9
Delay discount hyperbolic model param0.20.33.3-0.00.1-0.3-0.30.30.40.3-0.30.50.20.4-0.4-0.30.4-0.40.2-0.20.30.91.8
Intermittent access intake day 1-15 change0.10.61.6-0.90.9-0.7-0.80.70.90.4-0.40.80.71.3-0.8-1.20.5-0.50.5-0.5-0.9-0.7-1.0
Intermittent access intake escalation0.21.22.4-1.31.3-1.1-1.11.11.20.8-0.81.11.11.5-1.1-1.60.9-0.90.9-0.9-1.2-0.8-1.1
Intermittent access intake escalation 20.61.02.0-1.21.1-0.9-0.90.91.10.7-0.70.61.21.4-0.9-1.40.9-0.90.8-0.8-1.1-0.6-1.1
Intermitt. access day 1 inactive lever presses0.10.81.7-0.90.9-1.0-1.11.01.10.8-0.81.10.80.8-1.3-0.90.8-0.80.8-0.8-0.5-0.40.5
Intermitt. access day 15 inactive lever presses0.10.51.7-0.80.8-0.8-1.00.80.70.4-0.41.30.40.6-0.8-0.60.4-0.40.4-0.4-0.5-1.1-0.1
Intermitt. access escalation Index0.20.61.1-0.70.7-0.6-0.70.60.90.8-0.80.40.90.8-0.7-0.80.9-0.90.9-0.9-0.41.10.8
Intermittent access day 1 total infusions0.10.30.80.7-0.70.60.4-0.5-0.6-0.60.60.0-0.9-0.50.20.4-0.50.5-0.60.60.1-0.1-0.2
Intermittent access day 15 total infusions0.20.51.4-0.60.6-0.6-0.70.60.70.5-0.51.20.31.0-0.9-1.00.5-0.50.5-0.5-0.9-0.3-0.4
Intermittent access terminal intake (last 3 days)0.00.10.20.1-0.10.10.0-0.1-0.0-0.20.20.5-0.30.3-0.2-0.4-0.20.2-0.30.3-0.3-0.3-0.5
Intermittent access total infusions0.10.10.90.00.0-0.1-0.10.2-0.00.0-0.01.0-0.30.2-0.4-0.30.1-0.1-0.00.0-0.4-0.4-0.5
Intermittent access day 1 locomotion0.00.10.3-0.20.2-0.2-0.40.20.20.3-0.30.40.20.2-0.5-0.10.0-0.00.1-0.1-0.5-0.5-0.4
Intermittent access day 15 total locomotion1.03.74.7-2.12.1-1.9-2.11.92.01.9-1.92.11.82.1-2.1-2.11.7-1.71.9-1.9-2.2-1.6-1.4
Intermittent access total locomotion1.72.03.4-1.41.4-1.4-1.61.41.41.5-1.51.81.31.5-1.7-1.51.3-1.31.3-1.3-1.6-1.1-1.1
Intermittent access standard deviation0.20.92.1-0.80.8-0.9-0.80.90.90.8-0.81.40.51.4-1.0-1.40.9-0.90.8-0.8-1.1-0.6-1.1
Left kidney weight0.00.11.90.0-0.00.0-0.0-0.0-0.1-0.30.30.5-0.20.3-0.2-0.3-0.10.1-0.10.1-0.1-0.4-1.4
Right kidney weight0.10.54.80.2-0.20.00.2-0.0-0.5-0.50.50.5-0.50.10.10.0-0.10.1-0.20.2-0.2-1.8-2.2
Cocaine induced anxiety0.10.21.70.2-0.10.10.2-0.10.1-0.00.0-0.5-0.1-0.2-0.10.10.0-0.0-0.10.10.61.21.3
Post-drug Anxiety0.10.10.50.2-0.20.20.3-0.2-0.2-0.20.2-0.4-0.2-0.50.30.4-0.20.2-0.20.20.60.60.7
Baseline Anxiety0.10.21.50.2-0.30.20.1-0.2-0.5-0.30.30.0-0.1-0.30.50.3-0.30.3-0.20.2-0.2-1.2-1.0
Tail length0.31.84.5-1.21.3-1.0-1.41.01.71.2-1.20.51.52.0-2.1-1.91.0-1.01.0-1.0-1.60.5-1.4
Length with tail0.20.76.4-0.60.6-0.4-0.80.40.70.3-0.30.20.61.2-1.1-1.00.3-0.30.3-0.3-1.1-0.6-2.5
Length without tail0.10.44.1-0.10.1-0.2-0.20.2-0.3-0.30.30.4-0.40.10.10.20.1-0.1-0.10.1-0.5-1.8-2.0
Times rat made contact with spout0.70.81.3-1.01.0-1.0-1.11.00.91.1-1.11.11.10.8-1.0-0.80.7-0.70.6-0.6-0.7-0.9-0.6
Lifetime Intake0.10.10.60.2-0.20.10.0-0.0-0.2-0.20.20.7-0.50.2-0.2-0.2-0.10.1-0.20.2-0.4-0.6-0.8
Liver weight, left0.40.71.61.1-1.11.01.2-1.0-1.0-0.70.7-0.6-0.7-0.70.70.6-0.70.7-0.70.70.5-0.4-1.3
Liver weight, right0.20.40.9-0.60.6-0.6-0.40.60.40.6-0.60.90.40.6-0.6-0.60.6-0.60.7-0.7-0.4-0.7-0.7
Locomotor activity0.40.61.0-0.70.7-0.8-0.50.80.90.6-0.60.10.50.9-0.9-0.80.9-0.91.0-1.0-0.9-0.7-0.2
Locomotor testing distance1.43.45.2-1.81.9-2.0-1.62.02.01.8-1.81.31.81.8-2.0-1.82.1-2.12.3-2.3-1.8-1.5-0.4
Locomotor testing rearing3.111.213.8-3.53.5-3.5-3.43.53.63.2-3.22.93.43.6-3.7-3.43.5-3.53.7-3.7-3.5-2.4-1.5
Locomotion in novel chamber0.70.92.21.1-1.11.11.2-1.1-0.8-0.90.9-1.5-0.8-0.90.91.0-0.90.9-0.90.90.80.70.8
Locomotion in novel chamber post-restriction0.10.31.50.2-0.30.30.1-0.3-0.3-0.70.7-1.0-0.20.10.70.2-0.40.4-0.60.6-0.6-1.0-1.2
Fecal boli incidents, locomotor time 10.61.62.81.2-1.31.41.2-1.4-1.6-1.11.1-1.4-0.8-1.51.71.4-1.31.3-1.31.31.00.4-1.0
Change in fecal boli incidents, locomotor task0.20.20.9-0.50.5-0.3-0.20.20.90.0-0.0-0.70.20.7-0.4-0.50.0-0.00.1-0.1-0.4-0.10.9
Time >=10cm from walls, locomotor time 11.11.32.31.4-1.51.31.4-1.2-1.5-1.21.2-0.7-1.3-1.21.31.1-1.01.0-1.31.30.9-0.1-0.5
Bouts of movement, locomotor time 11.31.73.2-1.21.3-1.1-1.51.21.31.0-1.01.31.41.6-1.4-1.81.2-1.21.2-1.2-1.6-0.5-1.6
Total resting periods, locomotor time 10.60.72.1-0.80.8-0.7-0.90.70.70.6-0.60.91.01.0-0.8-1.30.8-0.80.7-0.7-1.0-0.2-1.4
Rest time, locomotor task time 10.20.20.60.3-0.30.60.2-0.6-0.3-0.60.6-0.8-0.1-0.30.40.2-0.80.8-0.60.60.30.5-0.4
Distance moved, locomotor task time 10.51.44.0-1.11.1-1.3-1.01.41.01.4-1.42.00.71.0-1.1-1.01.4-1.41.4-1.4-0.9-0.90.1
Vertical activity count, locomotor time 10.10.72.6-0.60.7-1.0-0.91.00.70.7-0.71.60.10.7-1.0-0.60.9-0.90.6-0.6-0.8-1.3-0.3
Time >=10cm from walls, locomotor time 20.30.81.4-0.80.8-0.9-0.90.91.20.9-0.90.51.11.0-1.1-0.81.0-1.01.0-1.0-0.8-0.10.9
Bouts of movement, locomotor time 20.30.85.3-0.60.6-0.6-0.90.60.30.3-0.31.10.70.6-0.5-0.70.5-0.50.7-0.7-1.3-1.8-2.3
Total resting periods, locomotor time 20.20.96.7-0.70.6-0.6-0.80.60.30.3-0.31.00.70.6-0.4-0.70.4-0.40.5-0.5-1.4-1.9-2.6
Rest time, locomotor task time 21.52.63.61.4-1.51.71.6-1.7-1.6-1.71.7-1.7-1.5-1.51.81.5-1.91.9-1.91.91.50.80.1
Distance moved, locomotor task time 22.43.25.9-1.61.7-1.9-1.71.91.62.1-2.12.41.71.5-1.8-1.52.0-2.02.2-2.2-1.5-1.10.2
Vertical activity count, locomotor time 20.92.13.2-1.21.3-1.4-1.51.41.31.6-1.61.81.31.4-1.6-1.31.5-1.51.6-1.6-1.6-1.2-0.8
Light reinforcement 10.10.41.3-0.70.7-0.7-0.80.70.20.5-0.51.10.6-0.0-0.3-0.20.6-0.60.7-0.7-0.5-1.1-0.6
Light reinforcement 20.40.91.81.0-1.00.91.2-0.9-1.2-0.80.8-0.6-1.0-1.31.01.1-0.70.7-0.60.61.20.60.4
Bone: marrow area15.036.850.77.1-7.06.76.8-6.6-6.7-6.66.6-6.0-6.6-6.35.86.1-5.75.7-5.85.85.63.50.6
Bone: maximum diameter7.916.020.84.6-4.54.34.4-4.2-4.5-4.64.6-3.9-4.5-4.44.04.3-3.83.8-3.83.83.41.10.1
Bone: maximum force2.24.36.32.3-2.32.22.4-2.2-2.4-2.52.5-2.1-2.3-2.22.22.1-1.91.9-1.91.91.3-0.7-1.3
Bone: maximum moment1.73.14.52.0-2.02.02.0-1.9-2.0-2.12.1-2.0-1.9-1.81.81.7-1.61.6-1.61.60.9-0.6-1.3
Mean time between licks in bursts0.10.50.90.9-0.80.90.5-0.9-0.4-0.80.8-0.8-0.6-0.50.20.5-0.90.9-1.01.00.50.90.5
Mean num. licks in bursts0.41.22.2-1.11.1-1.0-1.21.00.81.2-1.21.11.20.9-0.7-1.00.9-0.90.9-0.9-1.3-1.5-1.4
Cd content in liver0.91.01.7-0.90.9-0.9-0.71.01.01.2-1.20.71.11.1-0.7-1.01.3-1.31.3-1.3-0.9-0.3-0.0
Co content in liver0.70.82.1-0.90.9-0.6-1.00.61.41.1-1.10.11.31.0-1.2-0.90.5-0.50.4-0.4-0.51.11.4
Cu content in liver0.20.20.40.4-0.40.40.4-0.4-0.5-0.50.5-0.4-0.5-0.60.50.5-0.40.4-0.30.30.60.30.3
Fe content in liver0.50.63.8-0.30.4-0.2-0.20.20.81.0-1.00.20.80.7-0.7-0.90.4-0.40.4-0.40.12.01.6
K content in liver2.12.03.21.2-1.31.21.3-1.2-1.6-1.81.8-1.0-1.7-1.81.61.6-1.61.6-1.51.51.2-0.7-0.1
Mg content in liver1.31.42.40.9-1.01.00.9-1.0-1.1-1.61.6-1.2-1.3-1.41.41.4-1.31.3-1.31.30.9-0.40.6
Mn content in liver1.61.83.31.2-1.31.31.2-1.3-1.6-1.51.5-1.1-1.4-1.81.81.6-1.41.4-1.41.41.1-0.30.4
Na content in liver1.11.21.71.0-1.11.11.2-1.1-1.3-1.31.3-0.7-1.0-1.21.31.0-1.21.2-1.31.31.0-0.5-0.3
Rb content in liver0.50.61.2-0.70.7-1.1-0.81.10.30.7-0.71.10.30.1-0.1-0.11.1-1.11.1-1.10.1-0.30.3
Se content in liver0.20.20.60.0-0.1-0.10.30.0-0.4-0.80.8-0.2-0.7-0.60.60.6-0.10.1-0.10.10.5-0.60.1
Sr content in liver0.20.20.40.3-0.20.5-0.0-0.50.20.2-0.2-0.30.30.1-0.2-0.1-0.60.6-0.60.6-0.10.50.6
Zn content in liver1.01.11.91.1-1.11.01.2-1.0-1.1-1.11.1-1.1-1.1-1.41.21.4-0.90.9-0.90.91.20.40.9
Bone: minimum diameter8.416.121.84.6-4.54.34.5-4.3-4.6-4.74.7-4.2-4.4-4.33.94.3-3.73.7-3.83.83.40.9-0.6
Time in familiar zone, hab. session 10.10.10.90.3-0.30.50.5-0.5-0.2-0.00.0-1.00.30.20.40.1-0.20.2-0.00.00.00.2-0.6
Time in novel zone, hab. session 10.20.31.3-0.50.5-0.7-0.70.70.30.1-0.11.1-0.1-0.0-0.5-0.30.5-0.50.4-0.4-0.2-0.90.3
Total zone transitions, hab. session 10.40.50.8-0.80.8-0.8-0.80.80.80.6-0.60.90.70.8-0.9-0.70.7-0.70.7-0.7-0.8-0.7-0.0
Total locomotion distance, hab. session 11.11.62.4-1.41.4-1.4-1.21.51.21.1-1.11.61.21.0-1.2-1.11.3-1.31.4-1.4-1.2-1.4-0.4
Locomotion velocity, hab. session 10.81.22.1-1.21.2-1.3-1.01.31.01.0-1.01.41.00.9-1.2-0.91.2-1.21.2-1.2-0.8-0.70.1
Time in familiar zone, hab. session 20.30.30.6-0.20.3-0.30.10.30.60.7-0.7-0.20.80.6-0.5-0.30.7-0.70.8-0.8-0.00.70.6
Time in novel zone, hab. session 21.51.73.41.1-1.11.10.8-1.1-1.5-1.71.7-0.4-1.9-1.51.41.3-1.51.5-1.61.60.8-0.8-0.0
Total zone transitions, hab. session 20.10.11.1-0.30.3-0.2-0.20.20.40.3-0.30.00.30.1-0.3-0.10.1-0.10.1-0.10.20.41.0
Total locomotion distance, hab. session 20.70.91.3-1.11.1-1.1-1.01.11.01.0-1.01.11.10.8-0.9-0.91.0-1.01.0-1.0-0.6-0.60.1
Locomotion velocity, hab. session 20.70.91.4-1.11.1-1.1-0.91.10.91.0-1.01.21.00.7-0.9-0.81.1-1.11.0-1.0-0.6-0.60.1
Novel to familiar place preference ratio0.10.20.6-0.30.3-0.2-0.30.20.50.3-0.3-0.10.40.5-0.6-0.70.2-0.20.3-0.3-0.8-0.2-0.7
Novelty place preference0.10.10.4-0.10.2-0.0-0.10.00.40.2-0.2-0.20.20.4-0.5-0.50.0-0.00.2-0.2-0.60.0-0.4
Time in novel zone, NPP test0.10.10.4-0.20.2-0.1-0.20.10.50.2-0.2-0.20.30.4-0.6-0.60.1-0.10.2-0.2-0.60.0-0.2
Total zone transitions, NPP test0.40.60.9-0.90.9-0.9-0.80.90.70.8-0.80.90.80.6-0.5-0.60.7-0.70.7-0.7-0.6-1.0-0.0
Total locomotion distance, NPP test2.63.65.3-2.22.1-2.3-1.82.31.71.7-1.72.11.81.5-1.5-1.42.2-2.22.1-2.1-1.5-2.0-0.3
Locomotion velocity, NPP test3.14.46.2-2.42.3-2.5-2.02.51.81.9-1.92.32.01.7-1.6-1.72.4-2.42.3-2.3-1.8-2.3-1.0
Intraocular pressure0.10.10.70.1-0.0-0.1-0.10.10.20.3-0.30.10.20.1-0.6-0.10.4-0.40.5-0.50.30.80.5
Delta distance traveled before/after self-admin0.20.21.1-0.20.2-0.4-0.30.40.30.6-0.60.40.60.2-0.4-0.10.6-0.60.6-0.60.20.41.0
Delta ambulatory time before/after self-admin0.00.00.20.2-0.20.20.1-0.1-0.20.1-0.1-0.10.1-0.10.20.30.1-0.10.1-0.10.30.40.4
Parametrial fat weight1.63.86.32.2-2.22.12.2-2.0-2.5-2.12.1-1.7-1.9-2.32.52.2-1.61.6-1.61.61.90.6-0.0
Pavlov. Cond. lever latency2.22.84.41.7-1.81.91.8-1.9-1.9-2.12.1-1.4-2.0-1.52.01.5-1.71.7-1.71.71.30.3-0.5
Pavlov. Cond. magazine entry latency0.70.91.4-1.11.1-1.2-0.81.11.20.9-0.90.51.00.7-1.0-0.81.1-1.11.1-1.1-0.6-0.40.6
Pavlov. Cond. change in total contacts1.92.03.7-1.51.6-1.6-1.51.51.91.4-1.40.71.51.5-1.8-1.51.4-1.41.4-1.4-1.1-0.21.0
Pavlov. Cond. index score1.31.72.6-1.41.4-1.6-1.31.61.41.5-1.51.01.40.9-1.4-1.01.5-1.51.5-1.5-0.9-0.60.5
Pavlov. Cond. latency score1.31.72.6-1.41.4-1.6-1.31.61.51.5-1.51.01.41.0-1.4-1.01.4-1.41.4-1.4-0.9-0.60.5
Pavlov. Cond. lever contacts1.61.92.9-1.51.5-1.6-1.51.51.61.7-1.71.11.61.3-1.6-1.31.4-1.41.4-1.4-1.2-0.40.1
Pavlov. Cond. magazine entry number0.91.21.91.2-1.21.41.0-1.3-1.3-1.01.0-0.7-1.0-0.81.10.9-1.31.3-1.31.30.90.7-0.6
Pavlov. Cond. intertrial magazine entries0.10.20.5-0.10.1-0.1-0.10.10.40.6-0.6-0.20.50.6-0.6-0.50.3-0.30.4-0.4-0.20.7-0.3
Pavlov. Cond. lever-magazine prob. diff.1.01.22.0-1.21.2-1.4-1.11.41.21.2-1.20.91.10.7-1.1-0.81.3-1.31.3-1.3-0.7-0.60.6
Pavlov. Cond. response bias0.91.11.7-1.21.2-1.3-1.01.21.31.1-1.10.61.10.8-1.1-0.81.2-1.21.2-1.2-0.8-0.40.7
Pavlov. Cond. lever latency0.81.12.2-1.11.1-1.3-1.01.20.91.5-1.51.21.10.9-0.9-0.51.2-1.21.0-1.0-0.40.30.3
Pavlov. Cond. magazine entry latency0.60.92.00.8-0.71.10.8-1.1-0.4-1.21.2-1.2-0.9-0.30.40.1-1.11.1-1.11.10.81.40.5
Pavlov. Cond. change in total contacts0.82.03.21.4-1.41.71.4-1.7-1.0-1.81.8-1.6-1.6-1.11.00.7-1.61.6-1.61.61.10.90.7
Pavlov. Cond. index score1.21.83.31.3-1.31.61.4-1.6-0.9-1.81.8-1.8-1.4-0.90.90.6-1.51.5-1.51.51.01.10.6
Pavlov. Cond. latency score1.01.63.01.2-1.21.51.3-1.5-0.8-1.71.7-1.7-1.4-0.90.80.6-1.41.4-1.41.41.01.10.6
Pavlov. Cond. lever contacts0.60.91.81.0-1.01.20.9-1.2-0.8-1.31.3-1.1-1.0-0.80.80.5-1.11.1-1.11.10.3-0.2-0.1
Pavlov. Cond. magazine entry number0.40.51.4-0.40.4-0.8-0.60.80.01.0-1.00.90.8-0.1-0.10.20.8-0.80.8-0.8-0.5-1.2-0.5
Pavlov. Cond. intertrial magazine entries1.02.34.61.6-1.61.31.5-1.3-2.1-1.51.5-1.0-1.6-2.02.02.0-1.21.2-1.31.31.1-1.1-1.0
Pavlov. Cond. lever-magazine prob. diff.1.21.83.11.3-1.31.61.4-1.6-0.9-1.81.8-1.8-1.4-0.90.90.6-1.51.5-1.51.51.11.10.6
Pavlov. Cond. response bias1.01.42.71.1-1.11.41.2-1.4-0.9-1.71.7-1.3-1.4-0.91.00.6-1.41.4-1.41.40.60.10.1
Time in closed arm before self-admin0.10.21.4-0.20.3-0.5-0.40.40.50.2-0.20.20.00.4-0.6-0.30.3-0.30.1-0.10.30.91.2
Time in closed arm after self-admin0.91.01.9-1.01.1-1.2-1.21.11.31.0-1.00.70.91.1-1.4-0.81.0-1.01.0-1.0-0.30.51.2
Time in open arm before self-admin0.20.30.5-0.60.6-0.5-0.60.40.60.3-0.30.30.50.6-0.6-0.50.2-0.20.3-0.3-0.7-0.6-0.6
Time in open arm after self-admin0.60.71.00.9-0.90.91.0-0.9-1.0-0.90.9-0.6-0.9-0.70.90.7-0.80.8-0.90.90.4-0.3-0.7
Bone: periosteal estimation7.317.524.34.9-4.84.64.8-4.5-4.8-4.74.7-4.1-4.7-4.54.14.4-3.83.8-3.83.83.61.5-0.4
Bone: periosteal perimeter5.310.414.53.8-3.73.63.5-3.5-3.6-3.63.6-3.2-3.5-3.43.03.4-3.23.2-3.13.12.71.2-0.3
Bone: post-yield work2.74.77.52.4-2.42.22.3-2.1-2.7-2.62.6-1.9-2.4-2.52.42.5-1.91.9-1.91.91.5-0.7-1.3
Progressive ratio test 1 active lever presses1.32.34.5-1.41.5-1.5-1.71.51.41.4-1.42.11.11.6-1.9-1.61.2-1.21.3-1.3-1.9-1.4-1.4
Progressive ratio test 1 breakpoint1.11.83.7-1.31.3-1.4-1.51.41.21.2-1.21.90.91.5-1.7-1.41.1-1.11.1-1.1-1.8-1.3-1.4
Progressive ratio test 1 inactive lever presses0.41.13.7-1.01.0-1.1-1.41.11.00.7-0.71.50.61.0-1.1-1.00.6-0.60.6-0.6-1.3-1.9-0.9
Progressive ratio test 2 active lever presses0.60.91.7-0.80.9-0.9-0.90.91.00.8-0.81.30.61.3-1.3-1.20.8-0.80.8-0.8-1.2-0.5-0.7
Progressive ratio test 2 breakpoint0.81.11.9-0.91.0-1.0-1.01.01.11.0-1.01.40.71.4-1.3-1.30.9-0.90.9-0.9-1.3-0.4-0.7
Progressive ratio test 2 inactive lever presses0.20.62.0-0.70.7-0.6-0.80.60.60.5-0.50.90.50.9-0.8-0.70.5-0.50.5-0.5-1.1-1.1-1.4
Incentive Sensitization - Responses0.00.10.4-0.20.2-0.2-0.30.20.40.3-0.30.40.20.6-0.5-0.50.3-0.30.2-0.2-0.5-0.3-0.6
Incentive Sensitization - Breakpoint0.10.20.4-0.30.3-0.3-0.30.30.40.4-0.40.40.20.6-0.5-0.60.4-0.40.3-0.3-0.5-0.3-0.5
Sum of active levers in priming session hrs 5-60.30.30.7-0.70.7-0.6-0.70.60.80.6-0.60.40.50.6-0.7-0.50.5-0.50.5-0.5-0.40.20.5
Progressive ratio1.23.66.22.1-2.12.12.3-2.1-1.9-1.91.9-2.5-1.9-1.92.01.8-1.81.8-1.81.81.81.30.6
Food seeking constrained by brief footshock0.10.11.00.1-0.10.30.2-0.20.1-0.00.0-0.8-0.10.40.0-0.3-0.10.10.0-0.0-0.01.00.3
Seeking ratio, punishment vs. effort1.22.73.9-1.71.7-1.6-1.91.61.81.7-1.71.81.72.0-1.7-1.81.6-1.61.6-1.6-1.7-0.6-0.6
Retroperitoneal fat weight1.56.98.1-2.72.7-2.7-2.82.72.72.7-2.72.62.72.8-2.9-2.82.7-2.72.7-2.7-2.7-1.4-1.7
Reaction time number correct0.72.33.31.7-1.71.71.7-1.7-1.7-1.61.6-1.8-1.5-1.51.71.6-1.51.5-1.61.61.10.0-0.3
Reaction time mean minus median0.21.62.41.3-1.31.41.3-1.4-1.2-1.21.2-1.5-1.1-1.21.21.1-1.51.5-1.51.51.20.80.2
Reaction time mean minus median AUC0.74.66.12.3-2.32.22.4-2.2-2.5-2.32.3-2.1-2.2-2.52.52.2-2.12.1-2.22.22.10.50.2
Reaction time num false alarms0.40.61.30.8-0.80.90.8-0.9-0.8-1.01.0-1.2-1.1-0.70.80.8-0.70.7-0.70.70.20.3-0.5
Reaction time num false alarms AUC1.12.64.01.7-1.71.81.7-1.8-1.7-1.91.9-2.0-1.9-1.61.71.6-1.61.6-1.61.61.00.6-0.3
Reaction time trials correct on left0.72.33.31.7-1.71.71.7-1.7-1.7-1.61.6-1.8-1.5-1.51.71.6-1.51.5-1.61.61.10.0-0.3
Reaction time trials on left0.82.73.71.8-1.81.81.9-1.8-1.8-1.71.7-1.9-1.6-1.61.91.8-1.61.6-1.71.71.20.0-0.3
Reaction time mean0.20.30.70.5-0.50.70.4-0.7-0.1-0.40.4-0.6-0.4-0.00.10.1-0.90.9-0.80.80.40.80.8
Reaction time mean AUC0.20.51.00.7-0.60.80.4-0.8-0.2-0.50.5-0.6-0.6-0.10.10.1-1.01.0-1.01.00.50.90.8
Median of all reaction times0.20.21.40.3-0.20.40.1-0.40.2-0.10.1-0.3-0.30.3-0.2-0.2-0.60.6-0.60.60.30.91.2
Reaction time omissions2.74.56.22.2-2.32.32.2-2.3-2.4-2.32.3-2.2-2.0-2.52.42.2-2.22.2-2.22.21.70.20.2
Reaction time false alarm rate0.10.20.40.3-0.30.40.3-0.4-0.3-0.70.7-0.6-0.6-0.20.30.2-0.30.3-0.30.3-0.10.4-0.2
Reaction time premature initiation rate4.46.89.3-2.92.8-3.1-2.73.02.42.9-2.92.62.72.1-2.3-2.02.9-2.92.8-2.8-2.4-2.0-1.3
Reaction time premature initiations0.51.52.8-1.31.2-1.5-1.11.40.81.3-1.31.11.20.6-0.6-0.51.4-1.41.3-1.3-1.2-1.7-1.2
Std. dev. reaction times0.51.52.01.3-1.31.31.2-1.3-1.2-1.31.3-1.4-1.2-1.21.31.1-1.41.4-1.41.41.00.40.3
Reaction time trials completed0.82.73.71.8-1.81.81.9-1.8-1.8-1.71.7-1.9-1.6-1.61.91.8-1.61.6-1.71.71.20.0-0.3
Reaction time trials AUC0.72.33.21.7-1.71.71.7-1.7-1.7-1.61.6-1.8-1.5-1.61.71.7-1.51.5-1.61.61.1-0.1-0.3
Run reversals in cocaine runway, females3.74.25.5-2.32.3-2.3-2.12.32.22.3-2.32.12.11.9-2.0-2.02.2-2.22.2-2.2-1.4-0.1-0.1
Run reversals in cocaine runway, males0.20.20.7-0.10.1-0.2-0.10.30.10.6-0.60.80.30.3-0.4-0.10.6-0.60.6-0.6-0.20.6-0.1
Latency to leave start box in cocaine runway0.50.73.8-0.70.8-1.0-1.01.00.50.8-0.82.00.40.4-0.9-0.80.8-0.80.7-0.7-0.5-0.9-0.5
Latency to leave start box in cocaine runway, F3.13.912.2-1.71.8-2.1-2.12.11.41.9-1.93.51.31.6-1.9-1.91.9-1.91.7-1.7-2.0-2.2-2.0
Latency to leave start box in cocaine runway, M1.01.05.40.7-0.70.60.8-0.6-0.5-0.70.7-0.9-0.7-1.00.70.8-0.70.7-0.70.71.71.62.3
Std. dev. time between licks in bursts0.20.30.9-0.60.6-0.5-1.00.50.70.5-0.50.60.70.6-0.6-0.80.4-0.40.4-0.4-0.8-0.3-0.2
Total sessions with >9 infusions0.70.82.6-0.70.7-0.7-0.90.70.60.7-0.71.30.41.0-0.8-1.00.5-0.50.5-0.5-1.3-1.5-1.6
Short access day 1 total inactive lever presses0.40.83.1-0.50.5-0.7-1.00.70.40.7-0.71.40.40.8-0.7-0.70.6-0.60.5-0.5-1.2-1.7-1.5
Short access day 10 total inactive lever presses0.00.31.00.5-0.50.50.3-0.5-0.2-0.60.6-0.8-0.5-0.50.20.6-0.60.6-0.60.60.3-0.11.0
Short access day 1 total infusions0.30.72.9-0.50.5-0.5-0.70.60.50.5-0.51.10.30.9-0.7-1.00.5-0.50.5-0.5-1.3-1.4-1.7
Short access day 10 total infusions0.60.96.7-0.30.3-0.4-0.60.40.00.3-0.31.20.00.7-0.3-0.70.3-0.30.2-0.2-1.6-2.3-2.6
Short access total infusions0.10.21.40.1-0.10.0-0.1-0.0-0.1-0.10.10.6-0.30.4-0.2-0.3-0.10.1-0.20.2-0.7-1.0-1.2
Short access day 1 locomotion4.16.79.4-2.52.5-2.6-2.82.62.32.6-2.63.02.32.6-2.6-2.62.5-2.52.5-2.5-3.1-2.6-2.4
Short access day 10 total locomotion0.10.40.8-0.40.5-0.3-0.60.40.60.9-0.90.60.60.7-0.9-0.70.6-0.60.6-0.6-0.90.1-0.6
Short access total locomotion1.52.24.0-1.41.4-1.3-1.61.31.21.5-1.51.81.21.5-1.4-1.41.3-1.31.3-1.3-2.0-1.8-2.0
One hour access (0.3 mA shock)0.20.20.30.6-0.60.50.6-0.4-0.5-0.50.5-0.1-0.5-0.10.40.3-0.40.4-0.50.50.2-0.3-0.4
Compulsive drug intake0.30.51.00.8-0.80.60.6-0.6-1.0-0.60.6-0.4-0.6-0.90.81.0-0.60.6-0.60.60.7-0.5-0.5
One hour access (shock baseline)0.10.30.60.7-0.70.60.8-0.6-0.5-0.70.7-0.3-0.8-0.40.50.4-0.60.6-0.70.70.50.30.3
Social response proportion0.70.91.90.8-0.80.51.0-0.6-1.2-1.11.1-0.7-1.4-1.21.31.3-0.50.5-0.70.71.0-1.3-0.6
Social responses0.20.22.8-0.10.0-0.1-0.10.1-0.2-0.00.0-0.2-0.1-0.20.40.2-0.10.1-0.20.2-0.3-1.7-0.8
Social time0.40.71.80.7-0.70.51.0-0.6-1.0-0.60.6-1.1-0.7-1.31.21.2-0.30.3-0.30.31.10.30.6
Soleus weight0.41.32.31.2-1.21.01.3-1.0-1.3-1.31.3-1.4-1.2-1.41.11.5-0.90.9-0.90.91.30.80.4
Bone: stiffness2.54.66.82.3-2.32.32.6-2.2-2.5-2.62.6-2.0-2.4-2.02.22.2-1.91.9-1.91.91.4-1.0-1.6
Tibialis anterior weight0.62.03.51.7-1.61.61.3-1.6-1.2-1.21.2-1.2-1.2-1.30.81.2-1.61.6-1.61.61.71.91.1
Time to tail flick, vehicle, before self-admin0.10.10.5-0.40.4-0.3-0.50.30.30.1-0.10.40.10.2-0.4-0.2-0.00.00.1-0.1-0.4-0.7-0.7
Time to tail flick, vehicle, after self-admin0.30.61.20.7-0.70.81.1-0.8-0.8-0.70.7-1.0-0.9-0.90.90.8-0.60.6-0.70.70.60.7-0.2
Time to tail flick, test, before self-admin0.20.20.7-0.20.3-0.2-0.30.20.70.6-0.6-0.10.50.6-0.8-0.60.4-0.40.5-0.5-0.50.60.7
Time to tail flick, test, after self-admin0.40.44.30.0-0.10.2-0.0-0.2-0.3-0.10.1-0.0-0.3-0.00.20.1-0.50.5-0.20.2-0.7-2.1-1.7
Delta time to tail flick, vehicle, before/after SA0.70.81.70.9-0.90.91.0-0.9-1.2-0.80.8-0.6-1.0-1.11.30.9-0.80.8-0.90.90.2-0.5-1.0
Delta time to tail flick, test, before/after SA0.30.31.80.3-0.30.40.4-0.4-0.6-0.50.5-0.3-0.5-0.30.80.3-0.50.5-0.50.5-0.1-1.1-1.3
Tibia length0.20.51.6-0.50.6-0.6-0.80.60.90.8-0.80.80.60.8-1.3-1.10.5-0.50.4-0.4-0.21.0-0.1
Ambulatory time before self-admin0.51.52.1-1.31.3-1.3-1.21.31.51.4-1.40.71.41.1-1.2-1.01.3-1.31.4-1.4-0.90.11.1
Ambulatory time after self-admin1.01.62.5-1.11.1-1.2-1.11.21.31.6-1.60.61.51.0-1.1-0.71.5-1.51.5-1.5-0.50.71.6
Bone: tissue strength0.91.01.6-1.21.1-1.1-1.31.11.01.0-1.00.91.11.0-0.6-1.00.8-0.80.8-0.8-1.2-1.2-0.4
Total heroin consumption3.54.15.72.1-2.12.11.9-2.1-2.3-2.12.1-1.7-2.4-2.22.12.2-2.42.4-2.32.31.80.20.2
Bone: trabecular number4.38.010.92.9-2.92.83.1-2.8-3.0-3.03.0-2.6-3.1-3.13.33.3-2.92.9-2.92.92.80.51.1
Bone: trabecular spacing5.07.39.1-2.82.8-2.8-2.82.82.83.0-3.02.63.03.0-2.8-2.92.8-2.82.8-2.8-2.4-0.6-1.0
Bone: trabecular thickness2.63.64.62.1-2.12.02.1-2.0-2.0-2.12.1-2.1-2.0-2.12.12.1-1.81.8-1.81.81.60.20.1
Bone: trabecular tissue density0.61.01.7-1.11.1-0.8-1.00.81.01.0-1.01.01.31.2-1.1-1.20.8-0.80.8-0.8-0.9-0.5-1.3
Water consumed over 24 hours0.10.21.6-0.20.2-0.2-0.50.2-0.1-0.10.10.9-0.1-0.10.10.2-0.20.2-0.30.3-0.1-1.3-0.4
Number of responses in last shaping day1.82.33.1-1.51.5-1.5-1.61.51.61.7-1.71.71.61.6-1.6-1.71.6-1.61.7-1.7-1.6-0.3-0.4