Hub : Genes

Kcnj16

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA alternative polyA XM_006247570.3 0.07 0.04 5.7e-04 0.07 0.07 0.08 0.08 8.2e-04 4.9e-04 2.2e-04 3.6e-04
2 pVTA gene expression Kcnj16 0.28 0.09 0.0e+00 0.34 0.37 0.37 0.37 1.3e-15 3.9e-17 3.3e-17 8.1e-17
3 pVTA alternative polyA NM_053314.3 0.08 0.05 6.6e-04 0.04 0.06 0.04 0.05 5.8e-03 1.3e-03 9.0e-03 4.4e-03
4 Brain alternative TSS NM_053314.3 0.23 0.08 0.0e+00 0.31 0.28 0.3 0.31 4.5e-29 7.1e-26 3.0e-28 5.5e-29
5 Brain alternative TSS XM_006247570.3 0.23 0.08 0.0e+00 0.31 0.28 0.3 0.31 3.1e-29 4.5e-26 1.4e-28 2.8e-29
6 Brain gene expression Kcnj16 0.25 0.07 0.0e+00 0.4 0.39 0.4 0.41 9.8e-40 1.4e-38 4.1e-40 8.6e-41
7 LHb gene expression Kcnj16 0.47 0.13 8.2e-12 0.41 0.44 0.4 0.41 9.9e-11 6.9e-12 1.3e-10 5.9e-11
8 Brain isoform ratio NM_053314.3 0.04 0.02 2.1e-05 0.07 0.05 0.06 0.06 3.5e-07 1.6e-05 2.1e-06 3.8e-06
9 Brain isoform ratio XM_006247570.3 0.04 0.02 2.3e-05 0.07 0.05 0.06 0.06 4.0e-07 1.7e-05 2.1e-06 4.5e-06
10 PL gene expression Kcnj16 0.04 0.03 1.0e-05 0.03 0.03 0.03 0.03 1.1e-04 2.4e-04 3.4e-04 4.4e-04
11 pVTA isoform ratio NM_053314.3 0.38 0.14 5.0e-13 0.26 0.24 0.29 0.28 2.0e-11 7.0e-11 7.8e-13 2.0e-12
12 pVTA alternative TSS XM_006247570.3 0.27 0.08 2.6e-15 0.32 0.34 0.32 0.31 2.6e-14 1.3e-15 3.0e-14 6.5e-14
13 pVTA alternative TSS NM_053314.3 0.27 0.08 1.0e-14 0.31 0.33 0.31 0.3 5.5e-14 6.3e-15 8.8e-14 1.2e-13
14 pVTA isoform ratio XM_006247570.3 0.41 0.14 2.9e-14 0.28 0.27 0.32 0.3 1.5e-12 6.3e-12 2.9e-14 1.1e-13
15 NAcc alternative TSS XM_006247570.3 0.05 0.06 7.0e-03 -0 0.01 0.03 0 9.6e-01 5.5e-02 1.9e-04 2.5e-01
16 NAcc alternative TSS NM_053314.3 0.05 0.06 6.7e-03 -0 0.01 0.01 0 6.4e-01 6.1e-02 1.8e-02 1.8e-01
17 RMTg mRNA stability Kcnj16 0.2 0.11 4.9e-03 0.06 0.04 0.04 0.05 8.4e-03 2.9e-02 3.1e-02 1.7e-02
18 BLA gene expression Kcnj16 0.11 0.06 1.5e-03 0.02 0.03 0.02 0.03 3.4e-02 1.2e-02 4.0e-02 7.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density5.18.511.13.3-3.13.1-3.1-3.13.13.1-2.92.9-3.1-3.3-2.92.93.22.5-2.62.21.0
Area under the delay curve0.20.20.80.5-0.40.1-0.3-0.30.30.4-0.50.5-0.20.1-0.10.10.00.9-0.8-0.4-0.9
BMI with tail3.110.114.3-2.33.1-3.23.63.6-3.3-3.73.3-3.33.52.93.2-3.2-2.9-3.63.8-2.9-1.0
BMI without tail1.53.05.3-0.61.6-1.72.02.0-2.0-2.11.9-1.92.31.71.5-1.5-1.7-1.61.9-1.60.0
Body weight1.56.311.0-2.22.3-2.52.52.6-2.9-3.33.1-3.12.61.92.2-2.3-1.8-2.52.6-2.7-1.0
Weight adjusted by age2.52.98.1-1.51.7-1.31.71.6-1.3-1.71.0-1.01.42.11.6-1.6-2.1-2.82.8-0.7-0.0
Bone surface12.722.328.05.0-5.35.3-5.2-5.14.94.8-4.84.8-5.0-4.5-4.94.94.54.3-4.44.12.4
Bone volume9.416.020.24.5-4.54.5-4.5-4.54.34.3-4.14.1-4.2-3.9-4.14.13.83.5-3.63.11.4
Breakpoint value in progressive ratio session2.02.23.41.2-1.71.5-1.7-1.71.41.3-1.61.6-1.8-1.8-1.31.31.80.7-0.91.70.9
Number of licking bursts0.40.50.90.7-0.70.8-0.7-0.70.90.5-0.90.9-0.7-0.3-0.50.50.40.1-0.10.80.8
Context. condit. distance diff. score1.11.32.4-0.71.2-1.11.01.0-1.2-1.11.3-1.31.40.21.2-1.3-0.4-1.21.3-1.5-0.9
Locomotion velocity, session 10.10.11.3-0.10.10.2-0.0-0.10.30.2-0.20.2-0.20.30.1-0.0-0.2-0.70.61.10.2
Locomotion distance, session 11.51.94.0-1.61.6-1.41.11.0-0.8-0.80.6-0.61.11.41.9-1.9-1.5-1.61.3-1.2-2.0
Locomotion velocity, session 20.10.10.9-0.6-0.10.0-0.2-0.1-0.10.00.2-0.2-0.4-0.4-0.40.40.40.2-0.31.00.3
Locomotion distance, session 20.20.31.4-1.00.5-0.4-0.1-0.10.10.20.1-0.1-0.10.40.8-0.7-0.4-1.00.60.1-1.2
Locomotion velocity, session 31.51.83.4-1.81.5-1.41.31.3-1.0-1.11.0-1.00.91.61.8-1.7-1.5-1.51.3-0.8-1.0
Locomotion distance, session 30.10.10.40.1-0.10.2-0.1-0.10.40.5-0.40.4-0.50.20.3-0.3-0.2-0.50.50.6-0.2
Stereotopy head waving bouts, day 30.20.20.5-0.50.4-0.30.20.2-0.00.10.1-0.10.3-0.40.7-0.70.3-0.40.3-0.7-0.7
Stereotopy head waving duration, day 30.10.10.5-0.1-0.10.20.00.00.10.00.1-0.1-0.1-0.7-0.10.10.70.4-0.4-0.00.5
Locomotion velocity, session 70.91.02.10.6-1.11.1-1.1-1.11.11.1-0.80.8-1.4-1.2-1.01.01.30.8-0.90.90.1
Locomotion distance, session 70.50.71.70.6-0.90.8-1.1-1.10.91.0-0.80.8-1.2-0.8-0.30.30.8-0.30.1-0.3-1.3
Stereotopy head waving bouts, day 70.40.44.10.2-0.00.10.40.4-0.1-0.30.1-0.1-0.0-0.6-0.30.30.60.6-0.51.22.0
Stereotopy head waving duration, day 71.01.27.70.5-0.70.8-0.2-0.30.50.3-0.50.5-0.8-1.0-1.01.01.01.1-1.02.22.8
Locomotion velocity, session 80.10.10.4-0.4-0.10.3-0.2-0.20.20.3-0.00.0-0.3-0.1-0.30.30.1-0.30.20.1-0.6
Locomotion distance, session 80.91.32.5-1.21.2-1.20.60.7-1.0-0.71.3-1.30.90.11.5-1.5-0.3-1.61.4-1.2-1.6
Degree of sensitization distance0.40.41.60.1-0.40.4-0.7-0.70.30.4-0.20.2-0.6-0.7-0.40.40.70.4-0.6-1.0-1.3
Degree of sensitization stereotypy0.50.66.40.10.1-0.00.70.6-0.4-0.60.4-0.40.2-0.2-0.30.30.20.4-0.21.42.5
Conditioned locomotion0.60.72.3-0.10.6-0.50.60.6-0.1-0.2-0.30.30.91.50.9-0.9-1.5-1.21.4-0.7-0.6
Cocaine response after cond. corrected0.10.20.70.8-0.30.4-0.3-0.40.50.5-0.60.6-0.00.0-0.20.2-0.2-0.10.20.3-0.4
Cocaine response after cond. not corrected0.20.21.41.2-0.60.6-0.4-0.40.50.4-0.60.6-0.2-0.4-0.50.40.20.10.00.40.1
Cocaine response before conditioning0.10.10.40.3-0.10.20.30.3-0.3-0.30.3-0.3-0.1-0.4-0.10.10.4-0.00.0-0.20.7
Saline control response2.63.58.3-2.11.8-2.01.31.4-1.5-1.21.4-1.41.81.92.0-2.0-1.9-2.11.9-2.1-2.9
Bone: connectivity density5.89.111.72.9-3.23.2-3.3-3.33.33.3-3.43.4-3.3-3.2-2.93.03.12.2-2.52.91.3
Bone: cortical apparent density6.18.011.8-3.43.3-3.32.82.8-3.0-2.82.8-2.82.62.23.3-3.3-2.4-2.42.3-2.5-2.4
Bone: cortical area0.30.53.6-0.00.4-0.3-0.2-0.2-0.1-0.20.2-0.20.50.11.0-1.0-0.3-0.40.3-1.3-1.9
Bone: cortical porosity2.83.05.52.1-1.71.8-1.3-1.21.11.1-0.90.9-1.3-2.2-2.32.32.22.1-1.81.82.0
Bone: cortical porosity2.22.44.91.9-1.61.7-1.2-1.21.01.0-0.80.8-1.1-1.7-2.22.11.71.9-1.61.61.7
Bone: cortical thickness12.821.027.8-4.95.3-5.34.44.4-4.8-4.54.7-4.74.73.55.2-5.2-3.8-3.73.5-5.1-4.2
Bone: cortical thickness4.35.08.5-2.02.3-2.41.81.8-1.8-1.61.8-1.82.02.32.9-2.9-2.3-2.72.6-2.4-2.1
Bone: cortical tissue density5.77.511.1-3.33.2-3.22.72.7-2.9-2.72.7-2.72.52.23.2-3.2-2.4-2.32.2-2.5-2.3
Condit. Reinf. active minus inactive responses0.60.71.4-0.20.5-0.60.80.8-0.8-0.90.8-0.81.01.00.6-0.7-1.1-1.11.2-0.40.8
Condit. Reinf. active-inactive response ratio0.10.11.10.6-0.40.4-0.2-0.20.10.1-0.10.1-0.1-0.0-0.30.3-0.1-0.20.20.41.0
Condit. Reinf. active responses0.91.11.9-0.40.9-0.91.21.1-1.1-1.21.0-1.01.31.21.0-1.0-1.3-1.21.4-0.70.5
Condit. Reinf. inactive responses0.81.01.7-0.51.1-0.91.00.9-0.8-0.90.7-0.71.21.21.2-1.2-1.3-1.01.1-1.0-0.5
Incentive salience index mean0.30.41.1-0.20.4-0.40.70.6-0.4-0.60.4-0.40.61.00.4-0.5-1.1-0.70.80.10.9
Condit. Reinf. lever presses0.50.61.3-0.80.9-0.81.11.0-0.7-0.80.7-0.70.81.10.7-0.7-1.1-0.50.6-0.00.3
Condit. Reinf. active minus inactive responses0.30.41.71.3-0.70.7-0.3-0.30.00.0-0.20.2-0.1-0.5-0.80.70.40.6-0.40.61.2
Condit. Reinf. active-inactive response ratio0.20.21.30.7-0.00.20.40.4-0.5-0.50.3-0.30.40.2-0.40.3-0.20.5-0.30.01.2
Condit. Reinf. active responses0.40.51.91.4-0.80.9-0.8-0.80.50.6-0.60.6-0.5-0.9-0.70.60.80.5-0.4-0.00.0
Condit. Reinf. inactive responses0.30.31.20.4-0.40.5-0.7-0.70.70.8-0.60.6-0.6-0.7-0.00.10.6-0.40.2-0.4-1.1
Condit. Reinf. lever presses0.20.30.80.4-0.30.3-0.6-0.6-0.30.10.2-0.20.0-0.9-0.60.50.80.7-0.7-0.4-0.6
Condit. Reinf. lever reinforcers received0.30.41.71.3-0.70.8-0.8-0.70.40.5-0.40.4-0.3-0.9-0.50.50.80.4-0.3-0.2-0.3
Conditioned reinforcement - actives4.74.77.62.0-2.42.3-2.2-2.11.81.9-1.61.6-2.1-2.8-2.42.42.62.1-2.12.12.2
Conditioned reinforcement - inactives0.20.30.80.1-0.30.3-0.6-0.5-0.10.30.2-0.2-0.4-0.8-0.40.30.70.8-0.9-0.1-0.7
Conditioned locomotion0.60.71.30.8-1.00.8-1.0-0.90.60.6-0.50.5-0.8-1.1-1.01.01.11.1-1.10.40.1
Patch foraging indifference point 0 sec1.72.75.9-1.71.8-1.71.41.5-2.1-1.72.2-2.21.80.11.2-1.3-0.3-0.40.4-2.3-2.4
Patch foraging indifference point AUC0.70.83.4-1.20.9-0.90.70.7-0.6-0.70.8-0.80.81.80.7-0.6-1.6-0.60.6-0.7-0.7
Delay disc. indifference point, 0s delay0.20.20.5-0.10.4-0.50.50.5-0.4-0.40.2-0.20.5-0.00.6-0.6-0.0-0.10.2-0.7-0.7
Delay disc. indifference point, 16s delay0.80.82.01.3-1.00.8-0.6-0.60.80.8-1.01.0-0.6-0.6-0.80.80.61.4-1.20.60.6
Delay disc. indifference point, 2s delay0.40.44.7-0.2-0.2-0.2-0.4-0.40.20.4-0.40.4-0.30.40.3-0.3-0.10.6-0.7-0.9-2.2
Delay disc. indifference point, 24s delay1.71.63.21.8-1.41.3-0.9-0.91.11.1-1.21.2-0.7-0.7-1.51.50.61.8-1.51.31.5
Delay disc. indifference point, 4s delay0.50.52.6-0.50.3-0.70.40.4-0.3-0.30.2-0.20.41.20.8-0.8-0.9-0.50.4-1.0-1.6
Delay disc. indifference point, 8s delay0.50.51.3-0.60.5-0.90.50.5-0.6-0.40.5-0.50.51.00.9-0.8-0.7-0.20.2-1.0-1.2
Indifference point function ln k0.10.11.30.5-0.10.2-0.0-0.10.00.0-0.10.1-0.0-1.10.1-0.10.90.2-0.30.10.2
Indifference point function log k0.10.11.30.5-0.10.2-0.0-0.10.00.0-0.10.1-0.0-1.10.1-0.10.90.2-0.30.10.2
Patch foraging total patch changes 0 sec1.82.97.4-1.71.9-1.81.31.4-2.1-1.72.2-2.21.80.41.5-1.5-0.6-0.70.6-2.4-2.7
Patch foraging total patch changes 12 sec1.82.35.0-1.41.7-1.61.31.4-1.5-1.21.5-1.51.81.01.4-1.4-1.1-1.11.2-2.0-2.2
Patch foraging total patch changes 18 sec3.34.35.6-2.32.3-2.31.92.0-2.3-2.12.4-2.42.32.31.7-1.7-2.3-1.31.3-2.3-1.8
Patch foraging total patch changes 24 sec0.70.92.9-0.81.0-0.90.60.6-0.9-0.70.9-0.91.11.20.8-0.8-1.3-0.30.4-1.5-1.7
Patch foraging total patch changes 6 sec2.94.38.1-2.22.2-2.32.12.2-2.7-2.72.9-2.92.41.81.4-1.5-1.8-0.70.8-2.0-1.1
Patch foraging time to switch 0 sec1.11.72.51.4-1.51.5-1.1-1.11.41.3-1.61.6-1.4-1.3-1.41.51.30.6-0.61.31.0
Patch foraging water rate 0 sec3.15.07.1-1.92.5-2.42.22.2-2.6-2.52.2-2.22.71.92.4-2.4-2.1-2.02.0-2.3-1.5
Patch foraging water rate 12 sec1.62.54.1-1.81.6-1.71.11.1-1.4-1.61.4-1.41.31.42.0-2.0-1.5-1.51.2-2.0-2.0
Patch foraging water rate 18 sec1.52.03.3-0.91.6-1.41.41.4-1.4-1.41.1-1.11.31.31.8-1.8-1.4-1.71.6-1.6-0.7
Patch foraging water rate 24 sec0.20.30.5-0.20.4-0.70.00.1-0.7-0.30.6-0.60.6-0.40.6-0.60.20.4-0.4-0.7-0.7
Patch foraging water rate 6 sec1.11.63.1-0.91.6-1.31.21.2-1.0-1.10.8-0.81.40.81.8-1.8-1.0-1.21.0-1.5-1.4
Seeking ratio, delayed vs. immediate footshock1.51.74.1-1.21.3-1.31.91.9-1.5-1.91.7-1.72.00.60.5-0.5-0.6-0.20.5-1.00.8
Distance traveled before self-admin0.40.40.80.10.6-0.50.90.9-0.8-0.70.8-0.80.90.30.5-0.5-0.3-0.50.6-0.60.1
Distance traveled after self-admin0.40.41.5-0.20.6-0.40.90.8-0.5-0.60.4-0.40.91.20.3-0.3-1.2-0.30.5-0.30.3
Extensor digitorum longus weight0.00.10.4-0.6-0.0-0.20.40.4-0.3-0.60.4-0.4-0.20.1-0.20.20.2-0.30.4-0.10.6
Bone: elastic displacement2.83.24.7-1.52.1-2.12.02.0-2.0-1.91.8-1.81.71.42.2-2.2-1.5-1.41.4-1.6-0.3
Bone: elastic work0.60.82.0-0.40.8-1.10.50.5-0.9-0.80.8-0.80.70.41.4-1.4-0.5-1.00.8-1.2-0.8
Bone: endosteal estimation15.233.048.46.9-6.97.0-6.5-6.46.35.8-5.85.8-5.8-4.7-6.06.05.04.5-4.44.83.2
Bone: endosteal perimeter14.129.242.96.5-6.46.5-6.1-6.16.05.5-5.85.8-5.4-4.3-5.45.44.44.3-4.34.62.5
Epididymis fat weight1.73.95.8-1.82.1-2.11.81.8-2.0-2.22.1-2.12.01.82.0-2.0-1.8-1.51.5-2.4-2.1
Delta time in closed arm before/after self-admin0.00.00.20.4-0.10.10.10.00.10.2-0.10.10.10.2-0.20.2-0.20.2-0.00.40.2
Delta time in open arm before/after self-admin0.90.82.00.6-0.60.9-1.0-1.01.11.3-1.01.0-1.0-1.4-0.60.61.30.6-0.70.4-0.4
Diff in mean of infusions in LGA sessions0.20.20.4-0.50.0-0.40.00.1-0.4-0.60.5-0.50.00.60.4-0.4-0.4-0.60.4-0.4-0.2
Delay discount exponential model param0.20.31.0-0.50.5-0.10.30.3-0.3-0.50.5-0.50.2-0.10.1-0.1-0.0-1.00.90.41.0
Extinction: sum of active levers before priming4.54.59.03.0-2.32.5-1.9-1.91.81.7-1.91.9-1.9-2.0-2.52.41.81.8-1.72.22.5
Active lever presses in extinction session 62.22.13.71.5-1.71.4-1.8-1.81.51.7-1.51.5-1.8-1.9-0.80.81.80.8-1.10.1-1.4
Bone: final force0.81.22.51.6-1.31.3-1.6-1.61.31.3-1.01.0-1.1-1.1-0.70.61.10.7-0.80.2-0.5
Bone: final moment0.61.02.41.5-1.11.2-1.3-1.31.01.0-0.70.7-0.9-1.2-0.60.61.20.8-0.9-0.0-0.4
Food consumed during 24 hour testing period0.30.40.9-0.7-0.30.2-0.8-0.80.50.4-0.10.1-0.4-0.8-0.60.60.70.7-1.00.1-0.8
Glucose0.10.20.9-0.1-0.0-0.0-0.5-0.50.10.10.2-0.2-0.20.60.5-0.5-0.6-0.70.5-0.4-1.0
Heart weight1.21.73.9-0.61.3-1.41.41.4-2.0-1.91.7-1.71.70.71.0-1.1-0.8-0.60.7-1.6-0.6
Delay discount hyperbolic model param0.20.31.7-0.30.30.00.30.3-0.2-0.40.4-0.40.2-0.4-0.00.00.2-0.90.80.61.3
Intermittent access intake day 1-15 change0.50.51.5-1.20.7-0.70.50.6-0.9-0.61.2-1.20.60.30.5-0.6-0.3-0.30.3-0.7-0.7
Intermittent access intake escalation0.40.41.1-1.00.6-0.70.40.5-0.8-0.51.1-1.10.50.30.5-0.5-0.2-0.20.2-0.5-0.6
Intermittent access intake escalation 20.40.40.9-0.70.6-0.60.40.4-0.8-0.40.9-0.90.70.70.2-0.2-0.60.5-0.4-0.5-0.7
Intermitt. access day 1 inactive lever presses1.41.53.2-1.51.4-1.21.01.0-1.0-1.10.7-0.71.01.81.2-1.2-1.7-1.11.0-1.0-1.8
Intermitt. access day 15 inactive lever presses1.01.13.5-1.71.1-1.10.70.7-0.8-0.90.6-0.60.81.91.0-1.0-1.6-1.10.9-0.4-0.9
Intermitt. access escalation Index0.30.22.10.10.2-0.20.60.6-0.5-0.50.6-0.60.5-0.0-0.20.10.10.00.2-0.11.4
Intermittent access day 1 total infusions0.50.61.70.4-1.00.8-1.0-0.90.60.6-0.40.4-1.1-1.3-0.70.71.30.3-0.40.50.2
Intermittent access day 15 total infusions0.20.21.3-0.3-0.40.3-0.5-0.4-0.10.10.4-0.4-0.6-1.1-0.20.21.2-0.0-0.10.1-0.1
Intermittent access terminal intake (last 3 days)0.80.91.70.3-1.11.0-1.2-1.20.70.9-0.40.4-1.2-1.2-1.01.01.30.9-1.00.80.2
Intermittent access total infusions0.20.20.7-0.4-0.50.4-0.7-0.60.20.30.0-0.0-0.8-0.7-0.20.30.8-0.1-0.00.2-0.3
Intermittent access day 1 locomotion0.10.10.3-0.3-0.0-0.0-0.1-0.10.0-0.20.1-0.1-0.1-0.50.1-0.10.5-0.10.0-0.3-0.5
Intermittent access day 15 total locomotion0.91.02.2-1.00.9-1.00.90.9-1.3-1.11.5-1.51.00.30.9-0.9-0.3-0.70.8-1.1-0.8
Intermittent access total locomotion0.60.61.3-1.10.6-0.80.60.6-0.9-0.91.1-1.10.5-0.10.7-0.70.1-0.90.8-1.0-0.8
Intermittent access standard deviation0.20.20.9-0.60.1-0.40.20.2-0.6-0.20.9-0.90.1-0.70.3-0.30.8-0.20.3-0.3-0.3
Left kidney weight0.20.53.4-0.2-0.30.0-0.2-0.2-0.3-0.30.8-0.8-0.2-1.8-0.40.41.90.4-0.50.00.6
Right kidney weight0.20.74.20.3-0.60.4-0.8-0.70.10.10.4-0.4-0.5-2.1-0.40.42.00.6-0.70.1-0.2
Cocaine induced anxiety0.80.91.9-0.71.1-0.91.01.0-0.9-0.90.6-0.61.01.40.8-0.9-1.4-0.70.8-0.9-0.7
Post-drug Anxiety0.10.21.1-0.10.4-0.20.20.2-0.1-0.1-0.20.20.30.70.2-0.2-0.70.0-0.0-0.6-1.1
Baseline Anxiety0.60.71.60.2-0.70.7-1.0-1.01.21.1-1.31.3-0.9-0.4-0.50.60.40.6-0.80.4-0.8
Tail length0.10.21.10.2-0.50.2-0.4-0.3-0.3-0.30.4-0.4-0.1-0.1-0.80.80.31.0-0.90.10.4
Length with tail0.10.31.1-0.90.1-0.4-0.2-0.2-0.7-0.71.0-1.00.10.1-0.00.00.10.5-0.6-0.8-0.7
Length without tail0.30.62.0-1.20.5-0.70.10.2-0.6-0.60.9-0.9-0.00.20.9-0.9-0.1-0.70.4-1.2-1.4
Times rat made contact with spout0.80.92.6-1.61.1-1.11.01.0-0.8-1.10.7-0.70.71.10.7-0.7-0.9-0.70.6-1.0-1.0
Lifetime Intake0.50.51.40.1-0.90.7-1.1-1.00.60.7-0.30.3-1.2-1.1-0.50.51.20.2-0.40.4-0.3
Liver weight, left0.91.53.51.1-1.31.2-1.5-1.51.21.4-0.90.9-1.1-1.9-0.90.91.80.8-0.91.10.5
Liver weight, right0.10.21.5-0.3-0.2-0.1-0.7-0.70.60.8-0.20.2-0.2-0.30.4-0.40.4-0.20.10.5-1.2
Locomotor activity0.50.71.9-0.10.7-0.60.50.6-0.9-1.01.0-1.00.90.50.9-0.9-0.6-1.41.3-0.8-0.5
Locomotor testing distance1.72.84.4-1.01.8-1.51.51.5-1.7-1.81.5-1.52.01.71.9-1.9-1.9-2.12.0-1.5-1.1
Locomotor testing rearing6.49.912.8-2.93.4-3.33.03.1-3.4-3.63.2-3.23.62.93.0-3.0-3.1-3.13.0-3.3-2.2
Locomotion in novel chamber0.60.81.81.3-0.81.0-0.8-0.80.70.8-0.80.8-0.7-0.8-1.00.90.61.2-1.10.60.5
Locomotion in novel chamber post-restriction0.70.82.80.2-0.10.1-0.6-0.60.20.6-0.00.0-0.3-1.6-0.20.21.41.6-1.7-0.9-1.4
Fecal boli incidents, locomotor time 11.41.55.00.7-1.11.0-0.9-0.91.31.5-1.21.2-0.8-1.1-1.21.31.32.2-2.10.4-0.3
Change in fecal boli incidents, locomotor task0.40.41.1-0.20.6-0.80.30.4-1.0-0.91.0-1.00.50.40.5-0.6-0.40.1-0.2-0.5-0.1
Time >=10cm from walls, locomotor time 11.31.32.70.8-0.91.3-1.2-1.21.31.4-1.21.2-1.3-1.6-1.01.01.60.9-1.00.6-0.3
Bouts of movement, locomotor time 11.51.63.5-1.81.3-1.51.31.4-1.7-1.61.9-1.91.50.20.8-0.8-0.1-0.20.3-1.3-0.8
Total resting periods, locomotor time 10.60.71.6-1.20.8-1.00.90.9-1.2-0.91.3-1.31.0-0.10.3-0.30.20.2-0.1-0.7-0.5
Rest time, locomotor task time 10.30.31.5-0.80.2-0.50.30.4-0.5-0.30.5-0.50.40.1-0.20.20.11.2-1.2-0.3-0.5
Distance moved, locomotor task time 11.61.88.5-0.81.1-0.90.90.9-0.7-0.80.6-0.60.51.11.7-1.6-1.1-2.92.8-0.7-0.4
Vertical activity count, locomotor time 10.91.05.0-0.80.8-0.50.20.3-0.4-0.70.3-0.3-0.11.01.2-1.2-1.0-2.21.9-0.8-0.9
Time >=10cm from walls, locomotor time 20.70.71.7-0.71.3-0.81.11.1-1.0-1.20.9-0.91.10.60.6-0.7-0.8-0.40.4-0.8-0.1
Bouts of movement, locomotor time 20.60.74.4-1.40.7-0.80.50.5-0.6-0.50.6-0.60.60.20.6-0.5-0.00.0-0.1-1.4-2.1
Total resting periods, locomotor time 20.70.74.9-1.40.7-0.90.40.4-0.6-0.40.7-0.70.60.10.5-0.50.10.3-0.4-1.5-2.2
Rest time, locomotor task time 22.12.45.11.1-1.71.3-1.6-1.61.51.7-1.41.4-1.4-1.1-1.61.61.22.3-2.21.60.7
Distance moved, locomotor task time 23.54.111.8-1.62.0-1.72.12.0-1.5-1.81.4-1.41.71.82.2-2.3-1.8-3.43.4-1.6-0.9
Vertical activity count, locomotor time 22.22.44.3-1.51.7-1.41.51.5-1.3-1.61.3-1.31.21.31.7-1.7-1.3-2.12.0-1.9-1.4
Light reinforcement 10.51.03.1-1.10.8-0.80.70.6-0.1-0.2-0.10.10.81.81.2-1.2-1.6-1.31.3-0.8-1.0
Light reinforcement 20.60.81.60.9-0.91.0-0.7-0.71.31.1-1.21.2-0.71.1-0.40.4-0.8-0.00.11.00.7
Bone: marrow area14.731.846.76.8-6.86.8-6.4-6.36.25.7-5.75.7-5.7-4.6-5.95.84.84.4-4.34.73.2
Bone: maximum diameter6.812.518.54.2-4.14.2-4.3-4.34.13.8-3.93.9-3.5-3.1-3.13.13.12.7-2.82.80.9
Bone: maximum force1.62.75.52.1-1.91.9-2.3-2.31.81.8-1.61.6-1.6-1.7-1.21.21.71.3-1.40.4-0.8
Bone: maximum moment1.32.24.12.0-1.71.7-2.0-2.01.41.5-1.21.2-1.4-1.8-1.21.11.71.4-1.50.1-0.7
Mean time between licks in bursts0.60.81.70.9-0.90.9-0.8-0.70.50.2-0.50.5-1.0-1.3-1.00.91.21.1-1.20.50.8
Mean num. licks in bursts0.91.12.9-1.51.2-1.21.01.0-1.0-0.81.0-1.00.90.91.0-1.0-0.9-0.50.4-1.3-1.7
Cd content in liver0.10.10.40.50.10.00.00.0-0.00.20.0-0.00.10.00.2-0.3-0.1-0.60.6-0.1-0.0
Co content in liver0.50.62.10.00.7-0.61.11.1-1.0-1.30.8-0.80.7-0.10.2-0.20.1-0.60.7-0.51.5
Cu content in liver0.70.91.50.9-1.11.0-1.2-1.21.11.1-1.11.1-0.9-0.5-0.80.80.70.7-0.61.10.5
Fe content in liver0.20.30.80.3-0.10.20.20.2-0.3-0.00.6-0.6-0.2-0.9-0.50.50.90.7-0.60.50.8
K content in liver3.63.66.51.8-2.01.9-2.5-2.62.32.3-2.42.4-2.1-1.5-1.21.21.61.2-1.41.5-0.1
Mg content in liver2.93.05.51.8-1.81.8-2.3-2.32.22.2-2.22.2-1.8-1.6-1.11.11.50.7-0.91.40.3
Mn content in liver4.04.56.81.9-2.22.0-2.6-2.62.32.6-2.52.5-2.1-2.4-1.61.62.31.9-2.11.30.3
Na content in liver2.72.94.81.3-1.71.7-2.2-2.21.71.9-1.61.6-1.8-2.0-1.41.51.91.7-1.71.3-0.1
Rb content in liver0.40.52.3-0.20.2-0.10.30.20.40.3-0.60.60.41.20.5-0.4-1.1-1.41.50.50.5
Se content in liver0.50.72.20.7-0.80.6-1.5-1.51.11.2-1.11.1-0.5-0.6-0.20.30.50.3-0.40.4-0.2
Sr content in liver0.20.20.50.0-0.10.20.10.2-0.3-0.30.3-0.3-0.5-0.7-0.70.70.70.7-0.7-0.4-0.0
Zn content in liver3.84.35.72.1-2.12.2-2.2-2.22.32.2-2.42.4-2.0-1.9-2.02.01.81.5-1.62.11.7
Bone: minimum diameter6.812.621.34.6-4.24.3-4.4-4.44.13.7-3.83.8-3.4-2.9-3.23.12.92.9-2.92.40.7
Time in familiar zone, hab. session 10.40.41.60.8-0.20.3-0.1-0.10.10.3-0.00.00.2-1.1-0.70.71.01.3-1.1-0.1-0.1
Time in novel zone, hab. session 10.70.72.3-1.00.5-0.60.20.2-0.3-0.40.2-0.20.21.31.1-1.1-1.2-1.51.3-0.0-0.5
Total zone transitions, hab. session 10.60.81.4-1.21.0-1.00.70.7-0.9-0.90.9-0.90.80.91.0-1.0-0.8-0.90.6-0.9-0.6
Total locomotion distance, hab. session 11.11.62.5-1.61.5-1.51.11.1-1.2-1.21.2-1.21.51.01.6-1.6-1.1-1.21.1-1.1-1.0
Locomotion velocity, hab. session 10.81.21.8-1.31.2-1.21.01.0-0.9-1.11.0-1.01.21.01.4-1.3-1.0-1.21.1-0.8-0.4
Time in familiar zone, hab. session 20.20.20.50.70.30.10.60.6-0.3-0.40.2-0.20.7-0.6-0.50.40.40.20.10.50.7
Time in novel zone, hab. session 20.90.92.60.1-1.00.7-1.6-1.61.21.3-1.21.2-1.6-0.10.1-0.00.3-0.1-0.30.2-0.6
Total zone transitions, hab. session 20.10.10.3-0.40.3-0.30.50.4-0.3-0.40.3-0.30.20.40.2-0.2-0.4-0.20.10.30.6
Total locomotion distance, hab. session 20.70.91.6-1.21.2-1.11.11.0-0.9-0.91.0-1.01.10.71.1-1.1-0.8-0.90.8-0.6-0.3
Locomotion velocity, hab. session 20.70.91.6-1.31.2-1.11.11.0-0.8-0.91.0-1.01.10.81.1-1.1-0.9-0.90.8-0.6-0.3
Novel to familiar place preference ratio0.30.30.7-0.10.2-0.30.30.3-0.6-0.60.8-0.80.30.80.4-0.5-0.7-0.20.2-0.7-0.3
Novelty place preference0.10.10.40.00.1-0.10.10.2-0.5-0.50.7-0.70.10.60.2-0.3-0.5-0.10.1-0.5-0.1
Time in novel zone, NPP test0.20.20.5-0.10.2-0.20.20.2-0.5-0.60.7-0.70.20.70.3-0.4-0.5-0.20.2-0.5-0.0
Total zone transitions, NPP test0.81.22.1-1.41.3-1.21.11.0-0.9-0.80.8-0.80.91.51.3-1.3-1.4-1.00.9-0.7-1.0
Total locomotion distance, NPP test3.14.27.2-2.12.4-2.31.91.8-1.6-1.51.6-1.62.32.12.7-2.7-2.2-2.22.2-1.5-1.6
Locomotion velocity, NPP test3.55.08.4-2.42.5-2.52.12.0-1.8-1.71.8-1.82.42.42.9-2.9-2.5-2.32.3-1.8-2.0
Intraocular pressure0.10.20.80.20.10.10.40.4-0.1-0.50.4-0.40.5-0.1-0.20.10.1-0.60.7-0.10.9
Delta distance traveled before/after self-admin0.40.41.7-0.70.8-0.50.80.8-0.4-0.50.3-0.30.71.30.4-0.4-1.3-0.40.5-0.10.3
Delta ambulatory time before/after self-admin0.10.10.5-0.20.20.00.20.20.10.1-0.10.10.20.7-0.10.0-0.70.2-0.00.10.2
Parametrial fat weight0.81.73.01.4-1.31.4-1.4-1.41.61.7-1.71.7-1.0-0.7-1.21.20.70.9-0.81.40.7
Pavlov. Cond. lever latency1.72.24.21.6-1.61.5-1.9-1.91.51.8-1.41.4-1.5-2.0-1.21.22.01.1-1.20.60.2
Pavlov. Cond. magazine entry latency0.60.81.6-0.50.9-0.80.80.8-0.8-1.00.6-0.61.11.10.7-0.7-1.2-1.21.2-0.20.0
Pavlov. Cond. change in total contacts1.51.63.1-0.91.3-1.31.41.4-1.6-1.81.4-1.41.51.41.0-1.0-1.5-1.21.1-0.70.3
Pavlov. Cond. index score1.11.43.6-0.91.2-1.11.31.2-1.0-1.30.8-0.81.41.91.0-1.0-1.9-1.31.3-0.4-0.1
Pavlov. Cond. latency score1.01.33.5-1.01.2-1.11.31.2-1.0-1.30.8-0.81.31.81.0-1.0-1.9-1.11.2-0.3-0.1
Pavlov. Cond. lever contacts1.21.53.5-1.21.3-1.21.51.4-1.2-1.41.0-1.01.21.90.9-0.9-1.8-0.90.9-0.5-0.0
Pavlov. Cond. magazine entry number0.60.71.50.3-0.80.8-0.8-0.70.80.9-0.60.6-1.1-1.1-0.70.71.21.1-1.10.5-0.1
Pavlov. Cond. intertrial magazine entries0.10.20.40.50.10.00.60.6-0.5-0.60.6-0.60.3-0.0-0.0-0.00.00.20.1-0.60.4
Pavlov. Cond. lever-magazine prob. diff.0.91.13.2-0.81.0-1.01.11.0-0.8-1.10.6-0.61.11.80.9-0.9-1.8-1.41.4-0.30.1
Pavlov. Cond. response bias0.91.12.5-0.61.0-1.01.11.0-1.0-1.10.7-0.71.21.50.9-0.9-1.6-1.31.3-0.30.3
Pavlov. Cond. lever latency0.91.22.6-1.11.0-1.11.41.4-0.7-1.00.8-0.81.01.60.9-0.9-1.5-1.11.3-0.40.2
Pavlov. Cond. magazine entry latency1.01.13.70.9-1.00.7-0.9-0.80.00.30.1-0.1-0.6-1.9-1.21.21.81.3-1.30.91.3
Pavlov. Cond. change in total contacts1.82.55.21.6-1.71.6-1.8-1.70.91.1-0.90.9-1.5-2.3-1.81.82.21.8-1.81.31.0
Pavlov. Cond. index score1.52.04.71.6-1.41.3-1.5-1.40.60.8-0.60.6-1.1-2.2-1.51.42.01.8-1.81.11.1
Pavlov. Cond. latency score1.51.84.21.5-1.41.3-1.5-1.40.60.8-0.60.6-1.0-2.0-1.41.41.91.7-1.71.11.2
Pavlov. Cond. lever contacts0.60.82.00.7-0.80.9-1.2-1.20.50.8-0.70.7-0.8-1.4-0.70.71.20.9-1.10.2-0.3
Pavlov. Cond. magazine entry number0.60.72.6-0.70.7-0.40.60.50.30.0-0.40.40.31.60.9-0.8-1.5-1.00.9-0.7-1.3
Pavlov. Cond. intertrial magazine entries1.72.25.61.1-1.41.6-1.8-1.82.32.3-2.42.4-1.40.4-0.70.8-0.30.7-0.80.8-1.2
Pavlov. Cond. lever-magazine prob. diff.1.82.25.31.6-1.51.4-1.6-1.50.60.9-0.70.7-1.1-2.3-1.61.62.21.9-1.91.21.2
Pavlov. Cond. response bias0.81.23.21.0-1.11.0-1.5-1.40.50.9-0.60.6-1.0-1.8-1.01.01.61.0-1.20.50.1
Time in closed arm before self-admin0.20.21.7-0.0-0.1-0.0-0.00.0-0.3-0.50.4-0.4-0.1-0.7-0.10.10.6-0.10.10.31.3
Time in closed arm after self-admin0.30.31.0-0.40.5-0.50.60.6-0.8-1.00.6-0.60.60.10.3-0.3-0.2-0.60.60.10.9
Time in open arm before self-admin0.30.30.6-0.60.4-0.70.50.5-0.6-0.70.7-0.70.60.80.6-0.6-0.7-0.50.4-0.5-0.6
Time in open arm after self-admin0.50.50.90.6-0.70.9-0.9-0.90.90.8-0.70.7-0.9-0.5-0.80.80.50.6-0.70.6-0.1
Bone: periosteal estimation6.613.722.84.8-4.54.5-4.5-4.44.23.9-3.93.9-3.6-3.1-3.53.43.22.9-2.82.41.1
Bone: periosteal perimeter4.98.212.73.6-3.43.5-3.4-3.43.22.8-2.92.9-2.8-2.5-2.82.82.62.4-2.52.10.7
Bone: post-yield work2.93.97.12.0-2.22.2-2.7-2.62.42.5-2.52.5-1.8-1.3-1.61.61.31.5-1.51.1-0.9
Progressive ratio test 1 active lever presses0.40.52.3-1.50.5-0.70.30.3-0.5-0.60.6-0.60.20.70.6-0.6-0.5-0.90.7-0.4-0.9
Progressive ratio test 1 breakpoint0.40.52.3-1.50.5-0.60.20.3-0.5-0.60.6-0.60.20.80.6-0.5-0.6-0.80.6-0.5-1.0
Progressive ratio test 1 inactive lever presses0.20.20.9-0.9-0.0-0.0-0.5-0.50.20.2-0.10.1-0.50.60.1-0.1-0.4-0.0-0.20.1-1.0
Progressive ratio test 2 active lever presses0.20.21.1-0.3-0.40.2-0.4-0.3-0.2-0.20.6-0.6-0.3-1.0-0.30.31.10.1-0.2-0.00.3
Progressive ratio test 2 breakpoint0.20.20.9-0.70.1-0.30.20.2-0.6-0.71.0-1.00.2-0.40.1-0.10.5-0.40.4-0.40.1
Progressive ratio test 2 inactive lever presses0.10.10.20.0-0.40.2-0.5-0.40.10.2-0.00.0-0.4-0.2-0.20.20.30.4-0.4-0.0-0.3
Incentive Sensitization - Responses0.20.21.10.2-0.40.4-0.5-0.40.00.20.3-0.3-0.3-1.0-0.50.51.00.6-0.60.10.1
Incentive Sensitization - Breakpoint0.20.20.80.1-0.30.3-0.3-0.2-0.10.00.4-0.4-0.1-0.9-0.40.40.90.5-0.50.00.1
Sum of active levers in priming session hrs 5-60.10.10.40.00.1-0.40.40.4-0.5-0.60.3-0.30.4-0.00.3-0.30.1-0.40.4-0.30.4
Progressive ratio3.23.76.52.5-2.22.2-1.9-1.91.92.0-2.02.0-2.0-1.5-1.91.91.51.8-1.71.91.2
Food seeking constrained by brief footshock0.20.31.40.4-0.50.3-0.2-0.1-0.20.00.4-0.4-0.1-0.6-0.70.60.61.2-1.00.10.9
Seeking ratio, punishment vs. effort1.72.13.7-1.91.5-1.71.51.5-1.7-1.71.9-1.91.50.71.3-1.3-0.7-0.90.9-1.6-0.7
Retroperitoneal fat weight1.34.28.3-2.21.9-2.12.12.1-2.7-2.72.9-2.91.80.81.6-1.6-0.8-1.81.7-2.5-1.1
Reaction time number correct1.52.12.91.6-1.51.6-1.6-1.61.51.7-1.41.4-1.3-1.6-1.31.31.51.7-1.70.6-0.0
Reaction time mean minus median1.62.14.11.0-1.41.4-1.4-1.41.31.3-1.21.2-1.4-1.5-1.71.71.62.0-2.01.10.8
Reaction time mean minus median AUC3.64.76.51.9-2.22.3-2.4-2.42.42.5-2.52.5-2.3-1.9-2.02.11.92.3-2.31.70.6
Reaction time num false alarms0.40.52.11.5-0.80.8-0.9-0.90.80.8-0.70.7-0.5-0.3-0.30.30.20.8-0.70.10.2
Reaction time num false alarms AUC1.62.25.02.2-1.61.6-1.7-1.71.61.7-1.61.6-1.3-1.2-1.21.11.11.6-1.50.60.4
Reaction time trials correct on left1.52.12.91.6-1.51.6-1.6-1.61.51.7-1.41.4-1.3-1.6-1.31.31.51.7-1.70.6-0.0
Reaction time trials on left1.72.43.41.7-1.61.7-1.8-1.81.61.8-1.51.5-1.4-1.7-1.41.41.61.8-1.80.6-0.0
Reaction time mean0.40.51.50.1-0.70.6-0.5-0.40.20.2-0.10.1-0.9-1.2-0.90.91.20.6-0.80.70.9
Reaction time mean AUC0.50.72.30.1-0.80.7-0.6-0.50.30.2-0.10.1-1.0-1.5-1.01.01.50.8-0.90.71.0
Median of all reaction times0.20.31.1-0.2-0.40.3-0.2-0.1-0.1-0.20.3-0.3-0.7-0.9-0.50.51.00.1-0.30.61.1
Reaction time omissions3.95.47.71.9-2.32.4-2.6-2.62.62.8-2.72.7-2.3-1.8-2.22.21.82.7-2.81.90.2
Reaction time false alarm rate0.10.10.80.9-0.40.3-0.4-0.40.30.3-0.30.3-0.10.0-0.10.1-0.00.4-0.4-0.00.3
Reaction time premature initiation rate4.56.08.5-2.22.8-2.72.72.6-2.1-2.21.8-1.82.72.92.6-2.5-2.8-2.42.5-2.3-1.9
Reaction time premature initiations1.01.52.6-0.91.4-1.31.21.1-0.8-0.70.5-0.51.41.61.4-1.4-1.5-1.11.2-1.4-1.6
Std. dev. reaction times1.31.82.81.0-1.31.4-1.4-1.41.21.3-1.21.2-1.4-1.7-1.41.41.61.6-1.70.90.5
Reaction time trials completed1.72.43.41.7-1.61.7-1.8-1.81.61.8-1.51.5-1.4-1.7-1.41.41.61.8-1.80.6-0.0
Reaction time trials AUC1.42.13.01.6-1.51.6-1.7-1.71.51.7-1.41.4-1.4-1.5-1.31.21.41.6-1.60.6-0.1
Run reversals in cocaine runway, females5.75.510.4-2.12.4-2.52.62.5-2.4-2.42.3-2.32.43.22.2-2.2-3.0-2.22.4-1.4-0.3
Run reversals in cocaine runway, males0.70.72.5-0.30.4-0.20.80.8-0.3-0.60.6-0.60.51.50.5-0.5-1.4-1.41.6-0.20.4
Latency to leave start box in cocaine runway1.51.65.1-1.91.1-1.20.90.9-0.9-1.10.8-0.80.81.41.3-1.2-1.2-2.32.1-0.6-0.8
Latency to leave start box in cocaine runway, F5.15.612.4-3.12.2-2.31.91.9-2.0-2.12.2-2.21.72.12.5-2.4-1.9-3.53.2-2.2-2.3
Latency to leave start box in cocaine runway, M0.50.53.40.4-0.40.4-0.3-0.30.50.2-0.70.7-0.20.1-0.70.7-0.10.4-0.31.31.8
Std. dev. time between licks in bursts0.30.30.9-0.90.6-0.70.40.5-0.8-0.70.8-0.80.30.20.3-0.3-0.20.3-0.4-0.9-0.4
Total sessions with >9 infusions0.10.10.7-0.4-0.0-0.2-0.3-0.2-0.00.10.0-0.0-0.3-0.10.3-0.30.2-0.40.2-0.1-0.8
Short access day 1 total inactive lever presses0.20.21.3-0.60.10.0-0.3-0.30.20.1-0.00.0-0.4-0.60.3-0.30.5-0.50.3-0.3-1.1
Short access day 10 total inactive lever presses0.20.31.60.20.4-0.10.10.1-0.0-0.2-0.20.20.21.30.2-0.3-1.2-0.0-0.0-0.5-1.1
Short access day 1 total infusions0.40.52.10.2-0.70.6-0.8-0.70.50.7-0.40.4-0.9-1.5-0.30.31.40.1-0.30.2-0.6
Short access day 10 total infusions0.40.43.7-0.5-0.30.2-0.8-0.70.30.60.0-0.0-1.0-0.30.3-0.20.4-0.30.0-0.7-1.9
Short access total infusions0.50.61.50.2-0.90.8-1.1-1.00.60.7-0.40.4-1.2-1.2-0.50.51.20.1-0.30.4-0.3
Short access day 1 locomotion1.71.93.4-1.61.4-1.31.11.1-1.1-1.11.1-1.11.01.21.6-1.6-1.2-1.61.5-1.6-1.8
Short access day 10 total locomotion0.10.10.30.2-0.2-0.0-0.00.0-0.2-0.20.2-0.20.0-0.6-0.20.10.40.1-0.1-0.4-0.2
Short access total locomotion0.40.41.9-0.70.5-0.60.20.3-0.5-0.50.6-0.60.20.00.7-0.7-0.1-0.70.5-1.1-1.4
One hour access (0.3 mA shock)0.40.41.00.3-0.70.9-0.8-0.70.80.7-0.30.3-0.8-0.7-0.80.80.70.4-0.41.00.4
Compulsive drug intake0.10.10.50.4-0.10.4-0.1-0.20.70.5-0.50.5-0.10.3-0.30.3-0.30.4-0.30.3-0.1
One hour access (shock baseline)1.51.72.71.0-1.41.4-1.5-1.41.11.3-0.90.9-1.5-1.6-1.31.31.61.1-1.11.50.8
Social response proportion0.80.82.01.4-0.70.8-1.1-1.11.21.3-1.31.3-0.80.10.2-0.2-0.2-0.50.50.6-1.0
Social responses0.30.42.9-0.10.5-0.20.10.10.20.3-0.30.30.00.90.7-0.7-0.9-0.30.2-0.6-1.7
Social time0.60.82.41.6-0.80.9-0.5-0.61.21.1-1.41.4-0.30.7-0.40.4-0.80.30.00.80.5
Soleus weight0.31.02.81.7-1.21.1-1.1-1.11.21.0-1.31.3-0.6-0.1-0.80.80.10.9-0.80.60.8
Bone: stiffness1.72.75.61.9-1.81.9-2.4-2.31.81.9-1.51.5-1.6-1.7-1.01.01.71.1-1.20.5-1.2
Tibialis anterior weight0.51.63.11.1-1.41.4-0.9-0.91.00.6-0.90.9-1.3-1.3-1.81.81.51.2-1.21.21.5
Time to tail flick, vehicle, before self-admin1.71.83.0-1.71.2-1.51.21.2-1.5-1.41.4-1.41.30.61.4-1.4-0.6-1.11.0-1.5-1.6
Time to tail flick, vehicle, after self-admin0.40.51.71.3-0.70.7-0.5-0.50.60.8-0.40.4-0.6-0.7-0.70.70.80.9-0.60.40.3
Time to tail flick, test, before self-admin0.10.10.40.5-0.20.20.20.2-0.3-0.50.2-0.20.2-0.2-0.30.30.2-0.00.10.10.6
Time to tail flick, test, after self-admin0.70.73.50.5-0.80.8-1.0-0.90.80.9-0.60.6-1.0-0.8-0.20.20.80.6-0.7-0.4-1.9
Delta time to tail flick, vehicle, before/after SA2.42.44.61.9-1.51.7-1.7-1.71.92.1-1.81.8-1.8-0.9-1.31.30.91.5-1.41.0-0.1
Delta time to tail flick, test, before/after SA1.00.91.80.8-0.91.0-1.2-1.11.01.3-0.70.7-1.2-1.1-0.60.61.11.1-1.20.1-0.9
Tibia length0.30.71.9-0.90.5-0.71.01.0-1.1-1.41.3-1.30.40.90.2-0.2-0.7-0.50.6-0.20.7
Ambulatory time before self-admin0.30.30.50.20.4-0.50.70.7-0.6-0.70.5-0.50.70.60.5-0.5-0.5-0.60.7-0.30.4
Ambulatory time after self-admin0.40.42.20.10.5-0.30.80.8-0.5-0.50.3-0.30.81.50.2-0.3-1.4-0.30.5-0.00.7
Bone: tissue strength1.00.92.1-1.21.1-1.30.80.8-1.1-0.70.8-0.81.00.41.2-1.1-0.5-0.40.4-1.5-1.2
Total heroin consumption4.04.77.01.7-2.52.2-2.6-2.62.52.5-2.52.5-2.7-2.1-1.91.92.21.7-1.91.70.1
Bone: trabecular number4.87.510.32.8-2.92.9-3.1-3.13.03.2-3.13.1-3.0-2.8-2.62.62.72.0-2.12.50.7
Bone: trabecular spacing5.57.19.4-2.72.8-2.83.13.1-2.8-2.92.9-2.92.93.02.3-2.3-2.9-2.12.3-2.3-0.8
Bone: trabecular thickness2.63.15.62.4-1.92.0-2.1-2.11.91.9-1.71.7-1.7-2.1-1.61.61.91.4-1.51.10.1
Bone: trabecular tissue density1.01.42.7-1.61.3-1.41.41.4-1.4-1.31.5-1.51.20.70.9-0.9-0.7-0.60.7-0.6-0.9
Water consumed over 24 hours0.20.21.2-1.10.5-0.5-0.00.00.1-0.00.1-0.10.10.20.6-0.6-0.2-0.2-0.1-0.7-1.0
Number of responses in last shaping day2.72.83.6-1.91.8-1.81.91.9-1.9-1.81.9-1.91.81.41.4-1.5-1.5-1.51.6-1.6-0.6