Hub : Genes

Jmjd7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	Jmjd7	0.08	0.04	7.5e-10	0.1	0.1	0.1	0.1	3.2e-09	1.3e-09	3.9e-09	3.3e-09
2	PL	gene expression	Jmjd7	0.03	0.02	1.6e-04	0.03	0.03	0.03	0.03	4.1e-04	1.1e-04	7.5e-04	2.1e-04
3	Liver	gene expression	Jmjd7	0.05	0.03	7.2e-03	0	0	0	0	1.3e-01	9.4e-02	1.0e-01	9.2e-02
4	Brain	alternative TSS	NM_001114656.1	0.03	0.02	5.4e-03	0.02	0.02	0.02	0.01	6.2e-03	1.0e-02	4.0e-03	1.3e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4
Bone: apparent density	0.7	1.1	2.5	1.6	1.3	-0.3	0.6
Area under the delay curve	2.9	3.4	5.8	1.8	2.4	-0.9	1.9
BMI with tail	3.8	13.3	20.8	4.6	3.9	-2.4	3.3
BMI without tail	4.3	13.0	26.3	5.1	4.2	-1.9	2.2
Body weight	4.3	18.9	30.0	5.5	4.6	-3.4	3.6
Weight adjusted by age	0.9	1.3	2.0	1.1	1.2	-1.4	0.8
Bone surface	0.4	0.7	1.8	1.4	0.7	-0.3	0.7
Bone volume	0.5	1.0	2.1	1.4	0.8	-0.4	0.9
Breakpoint value in progressive ratio session	0.3	0.3	0.8	-0.3	-0.6	0.9	-0.3
Number of licking bursts	0.3	0.5	1.5	-0.1	-0.4	1.2	-0.5
Context. condit. distance diff. score	0.7	0.9	2.5	1.6	0.8	0.1	-0.6
Locomotion velocity, session 1	1.2	1.3	3.1	-1.8	-0.8	0.7	-0.9
Locomotion distance, session 1	0.8	1.0	1.7	-1.1	-0.4	0.8	-1.3
Locomotion velocity, session 2	1.3	1.5	3.7	1.4	1.9	0.0	0.6
Locomotion distance, session 2	0.7	1.0	2.2	-0.4	-0.2	1.2	-1.5
Locomotion velocity, session 3	0.4	0.5	1.0	0.4	0.8	0.2	1.0
Locomotion distance, session 3	0.6	0.7	2.7	0.1	-0.1	1.6	-0.3
Stereotopy head waving bouts, day 3	3.8	4.5	4.9	1.9	2.2	-2.1	2.2
Stereotopy head waving duration, day 3	5.2	6.2	7.7	2.3	2.8	-2.3	2.5
Locomotion velocity, session 7	0.4	0.4	0.7	0.5	0.5	0.8	-0.7
Locomotion distance, session 7	1.0	1.3	3.3	-0.1	-0.5	1.3	-1.8
Stereotopy head waving bouts, day 7	0.3	0.3	1.0	-0.3	-0.1	-0.4	1.0
Stereotopy head waving duration, day 7	0.6	0.7	1.9	-0.3	-0.2	-0.9	1.4
Locomotion velocity, session 8	2.2	2.7	5.5	2.1	2.4	-0.5	0.7
Locomotion distance, session 8	0.9	1.2	2.6	1.1	0.7	0.8	-1.6
Degree of sensitization distance	0.7	0.7	1.1	-0.8	-1.1	-0.5	-0.9
Degree of sensitization stereotypy	0.5	0.5	1.2	-0.9	-1.1	0.2	0.2
Conditioned locomotion	1.1	1.3	2.9	1.7	1.4	-0.6	0.3
Cocaine response after cond. corrected	0.9	1.1	3.5	-0.5	-0.5	1.9	-0.5
Cocaine response after cond. not corrected	1.1	1.3	3.9	-0.7	-0.4	2.0	-0.7
Cocaine response before conditioning	0.1	0.1	0.2	-0.3	0.2	-0.1	-0.5
Saline control response	2.3	3.1	6.2	1.2	1.2	-2.5	1.8
Bone: connectivity density	0.4	0.6	0.9	0.7	0.6	-1.0	0.7
Bone: cortical apparent density	1.6	2.2	4.9	-1.6	-2.2	0.7	-0.8
Bone: cortical area	1.7	2.6	3.4	1.9	1.6	-1.3	1.6
Bone: cortical porosity	0.7	0.7	1.6	0.2	0.9	1.3	-0.7
Bone: cortical porosity	0.6	0.6	1.7	0.7	1.3	0.5	-0.1
Bone: cortical thickness	1.4	2.3	3.1	1.8	1.8	-1.0	1.4
Bone: cortical thickness	0.1	0.2	0.3	0.4	-0.0	0.5	0.5
Bone: cortical tissue density	1.5	2.0	4.6	-1.6	-2.1	0.7	-0.7
Condit. Reinf. active minus inactive responses	1.2	1.4	3.0	-1.5	-1.7	-0.5	-0.1
Condit. Reinf. active-inactive response ratio	0.3	0.4	0.7	-0.0	-0.2	-0.8	0.8
Condit. Reinf. active responses	2.8	3.5	7.3	-2.5	-2.7	-0.2	-0.7
Condit. Reinf. inactive responses	2.9	3.6	6.3	-2.3	-2.5	0.7	-1.5
Incentive salience index mean	2.2	2.7	5.2	-2.3	-2.3	-0.3	-0.6
Condit. Reinf. lever presses	1.5	2.2	4.2	-2.1	-1.9	-0.4	-0.9
Condit. Reinf. active minus inactive responses	0.3	0.4	1.2	0.2	-0.4	-1.1	0.4
Condit. Reinf. active-inactive response ratio	0.1	0.2	0.4	0.2	-0.5	-0.6	0.2
Condit. Reinf. active responses	0.6	0.8	2.4	0.4	-0.3	-1.6	0.8
Condit. Reinf. inactive responses	1.0	1.3	3.5	0.2	-0.0	-1.9	1.3
Condit. Reinf. lever presses	2.1	2.9	6.2	0.3	0.2	-2.5	2.3
Condit. Reinf. lever reinforcers received	0.7	1.0	3.0	0.1	-0.5	-1.7	0.8
Conditioned reinforcement - actives	0.1	0.1	0.2	-0.5	-0.2	0.2	-0.3
Conditioned reinforcement - inactives	0.2	0.3	0.7	0.3	0.0	0.8	-0.7
Conditioned locomotion	0.4	0.5	0.9	-0.3	0.5	-0.9	0.9
Patch foraging indifference point 0 sec	3.9	7.1	12.3	1.3	1.9	-3.5	3.3
Patch foraging indifference point AUC	1.6	2.3	4.1	-2.0	-1.7	0.9	-1.1
Delay disc. indifference point, 0s delay	1.1	1.2	2.6	0.0	0.7	-1.2	1.6
Delay disc. indifference point, 16s delay	1.0	1.1	2.2	0.7	1.3	-0.2	1.5
Delay disc. indifference point, 2s delay	0.2	0.3	0.6	0.8	0.5	-0.3	0.2
Delay disc. indifference point, 24s delay	0.2	0.3	0.9	-0.9	-0.3	0.4	-0.2
Delay disc. indifference point, 4s delay	1.3	1.3	3.0	1.3	1.7	-0.3	0.8
Delay disc. indifference point, 8s delay	5.8	6.8	9.5	2.5	3.1	-1.7	3.0
Indifference point function ln k	2.1	3.7	7.8	2.8	2.4	-0.7	0.9
Indifference point function log k	2.1	3.7	7.8	2.8	2.4	-0.7	0.9
Patch foraging total patch changes 0 sec	3.4	6.4	10.8	1.2	1.7	-3.3	3.3
Patch foraging total patch changes 12 sec	0.6	0.8	1.9	-0.7	-0.5	-1.4	0.9
Patch foraging total patch changes 18 sec	0.4	0.6	1.4	-1.2	-1.0	-0.2	-0.3
Patch foraging total patch changes 24 sec	1.4	2.5	3.7	1.1	1.4	-1.9	1.7
Patch foraging total patch changes 6 sec	0.4	0.5	0.9	-0.7	-0.4	-0.9	0.8
Patch foraging time to switch 0 sec	0.4	0.9	1.6	-1.3	-1.1	-0.8	0.3
Patch foraging water rate 0 sec	0.2	0.4	1.2	1.1	0.5	-0.1	0.4
Patch foraging water rate 12 sec	0.5	1.1	2.8	0.7	-0.1	1.7	-1.0
Patch foraging water rate 18 sec	0.6	1.0	2.0	1.4	1.1	0.8	0.3
Patch foraging water rate 24 sec	0.2	0.3	0.6	0.6	-0.4	0.8	0.3
Patch foraging water rate 6 sec	1.5	2.2	4.4	-0.7	-1.5	2.1	-1.3
Seeking ratio, delayed vs. immediate footshock	0.4	0.4	1.3	0.4	-0.4	0.3	-1.2
Distance traveled before self-admin	0.4	0.6	1.2	1.1	0.9	-0.3	0.5
Distance traveled after self-admin	0.0	0.0	0.1	0.1	-0.4	-0.1	0.1
Extensor digitorum longus weight	0.3	1.3	2.0	1.4	1.4	-0.4	1.2
Bone: elastic displacement	0.2	0.3	0.9	-0.1	0.2	-0.4	0.9
Bone: elastic work	1.2	1.6	3.9	0.6	0.6	-1.3	2.0
Bone: endosteal estimation	0.1	0.2	0.3	0.4	-0.1	0.6	-0.5
Bone: endosteal perimeter	0.0	0.0	0.1	0.1	-0.1	0.2	-0.3
Epididymis fat weight	0.5	1.6	3.4	1.6	1.8	-0.3	0.7
Delta time in closed arm before/after self-admin	0.8	0.7	2.1	-0.1	-0.4	0.8	-1.5
Delta time in open arm before/after self-admin	0.6	0.6	1.5	1.2	0.3	0.8	-0.2
Diff in mean of infusions in LGA sessions	0.3	0.4	0.7	-0.8	-0.8	-0.3	-0.2
Delay discount exponential model param	2.2	2.5	4.8	-1.6	-2.2	0.6	-1.5
Extinction: sum of active levers before priming	0.3	0.4	0.7	-0.9	-0.4	0.7	-0.3
Active lever presses in extinction session 6	0.1	0.1	0.2	-0.3	0.2	0.4	-0.3
Bone: final force	0.2	0.3	0.7	0.9	0.3	-0.6	0.4
Bone: final moment	0.2	0.3	0.6	0.8	0.2	-0.5	0.5
Food consumed during 24 hour testing period	0.3	0.3	0.9	0.1	-0.1	1.0	-0.7
Glucose	0.7	1.1	2.7	1.6	1.1	0.8	-0.1
Heart weight	2.7	4.1	8.8	3.0	2.4	-1.2	0.6
Delay discount hyperbolic model param	2.1	2.3	4.3	-1.6	-2.1	0.6	-1.4
Intermittent access intake day 1-15 change	0.3	0.7	1.7	1.0	0.3	1.3	-0.4
Intermittent access intake escalation	0.3	0.6	1.3	1.2	0.4	0.9	-0.0
Intermittent access intake escalation 2	1.6	1.8	5.3	0.7	0.2	2.3	-1.2
Intermitt. access day 1 inactive lever presses	0.4	1.6	2.9	1.3	1.4	-1.7	0.4
Intermitt. access day 15 inactive lever presses	0.1	0.3	0.7	0.9	0.5	-0.0	-0.1
Intermitt. access escalation Index	0.4	0.5	1.0	-0.0	-0.6	-1.0	0.9
Intermittent access day 1 total infusions	0.1	0.2	0.3	-0.5	-0.0	-0.3	0.5
Intermittent access day 15 total infusions	0.1	0.2	0.4	0.6	0.3	0.2	0.3
Intermittent access terminal intake (last 3 days)	0.3	0.4	0.9	0.7	0.3	1.0	-0.1
Intermittent access total infusions	0.1	0.1	0.1	0.3	0.3	0.0	0.4
Intermittent access day 1 locomotion	1.3	1.6	2.1	0.7	1.4	-1.5	1.4
Intermittent access day 15 total locomotion	0.3	0.6	1.3	1.1	0.8	0.6	-0.2
Intermittent access total locomotion	0.2	0.3	0.6	0.6	0.8	-0.1	0.4
Intermittent access standard deviation	0.2	0.5	1.2	0.7	0.3	1.1	-0.3
Left kidney weight	2.3	10.7	20.4	4.5	4.4	-1.6	0.8
Right kidney weight	3.6	16.3	27.9	5.3	5.3	-2.7	1.5
Cocaine induced anxiety	0.8	1.2	2.4	1.0	1.5	-1.2	0.2
Post-drug Anxiety	1.0	1.1	1.8	1.3	1.4	-0.6	-0.7
Baseline Anxiety	0.2	0.3	0.7	0.0	-0.4	0.4	-0.8
Tail length	1.1	4.4	11.0	3.3	2.4	-1.0	0.1
Length with tail	0.9	4.1	7.4	2.7	2.1	-1.8	1.2
Length without tail	0.6	2.0	2.6	1.6	1.4	-1.1	1.5
Times rat made contact with spout	0.7	0.8	1.2	0.6	0.8	-0.9	1.1
Lifetime Intake	0.2	0.2	0.6	0.1	0.3	-0.1	0.8
Liver weight, left	2.9	4.8	7.3	2.7	1.9	-2.1	1.8
Liver weight, right	2.6	4.5	5.2	2.3	2.2	-1.9	2.2
Locomotor activity	0.0	0.1	0.2	-0.5	-0.1	-0.0	-0.1
Locomotor testing distance	0.1	0.3	0.8	-0.9	-0.4	0.1	-0.2
Locomotor testing rearing	0.9	1.9	2.8	-1.7	-1.5	1.0	-1.2
Locomotion in novel chamber	0.3	0.4	0.7	0.4	0.5	-0.8	0.7
Locomotion in novel chamber post-restriction	0.6	1.0	2.7	1.6	0.9	-0.7	0.3
Fecal boli incidents, locomotor time 1	0.2	0.3	0.6	-0.8	-0.3	0.5	0.4
Change in fecal boli incidents, locomotor task	1.2	1.1	3.0	1.7	1.2	-0.3	0.1
Time >=10cm from walls, locomotor time 1	0.3	0.3	0.9	-0.2	-0.6	0.9	-0.4
Bouts of movement, locomotor time 1	1.8	2.0	4.1	-2.0	-1.5	1.1	-0.6
Total resting periods, locomotor time 1	2.2	2.4	4.8	-2.2	-1.7	1.1	-0.8
Rest time, locomotor task time 1	0.1	0.1	0.2	-0.3	-0.5	0.3	0.1
Distance moved, locomotor task time 1	0.2	0.3	0.3	-0.6	-0.5	-0.6	0.3
Vertical activity count, locomotor time 1	0.0	0.1	0.4	0.2	-0.2	-0.6	0.1
Time >=10cm from walls, locomotor time 2	5.1	7.6	10.4	3.2	2.7	-2.9	2.1
Bouts of movement, locomotor time 2	0.3	0.5	1.4	0.2	-0.3	-0.9	1.2
Total resting periods, locomotor time 2	0.3	0.4	1.1	0.0	-0.4	-0.7	1.0
Rest time, locomotor task time 2	4.1	5.3	6.4	-2.4	-2.1	2.5	-2.1
Distance moved, locomotor task time 2	1.8	2.2	3.9	1.3	1.2	-2.0	1.3
Vertical activity count, locomotor time 2	2.1	3.0	4.4	1.9	1.2	-2.1	1.6
Light reinforcement 1	1.8	4.3	11.6	-0.0	0.2	-3.4	2.4
Light reinforcement 2	0.7	1.0	2.2	-1.5	-1.3	-0.1	-0.5
Bone: marrow area	0.1	0.2	0.3	0.5	0.0	0.4	-0.4
Bone: maximum diameter	0.6	1.2	1.5	1.2	0.8	-1.1	1.2
Bone: maximum force	1.1	1.9	2.9	1.7	1.3	-1.4	1.1
Bone: maximum moment	0.9	1.6	2.4	1.5	1.2	-1.2	1.0
Mean time between licks in bursts	0.2	0.5	0.7	-0.6	-0.1	0.9	-0.9
Mean num. licks in bursts	0.7	1.1	2.5	0.5	0.8	-1.6	1.0
Cd content in liver	0.2	0.3	0.3	0.6	0.4	-0.5	0.6
Co content in liver	0.5	0.6	1.0	0.7	1.0	0.2	0.9
Cu content in liver	1.0	1.2	2.0	-0.5	-0.8	1.4	-1.4
Fe content in liver	3.0	3.6	7.7	-2.3	-2.8	0.4	-1.1
K content in liver	0.4	0.3	0.8	0.9	0.6	0.4	-0.1
Mg content in liver	0.8	0.8	1.9	1.4	0.7	0.8	0.5
Mn content in liver	1.5	1.6	2.1	1.5	1.4	-1.2	1.0
Na content in liver	0.7	0.7	1.1	-0.7	-0.8	0.8	-1.1
Rb content in liver	3.3	3.9	7.1	2.7	2.4	-0.4	1.5
Se content in liver	0.0	0.0	0.0	0.1	-0.0	0.2	-0.2
Sr content in liver	0.0	0.0	0.1	-0.1	0.3	-0.0	-0.0
Zn content in liver	1.5	1.7	2.3	-0.8	-1.5	1.4	-1.4
Bone: minimum diameter	1.9	3.5	5.2	2.0	2.3	-1.5	1.6
Time in familiar zone, hab. session 1	0.9	0.9	1.2	-1.0	-1.0	1.1	-0.8
Time in novel zone, hab. session 1	1.3	1.3	1.7	1.1	1.0	-1.3	1.2
Total zone transitions, hab. session 1	0.1	0.2	0.4	-0.5	-0.2	0.3	-0.7
Total locomotion distance, hab. session 1	0.1	0.2	0.4	-0.4	0.1	0.2	-0.6
Locomotion velocity, hab. session 1	0.2	0.2	0.5	-0.7	-0.1	0.1	-0.7
Time in familiar zone, hab. session 2	0.2	0.2	0.4	-0.0	-0.2	-0.4	0.7
Time in novel zone, hab. session 2	0.3	0.3	0.8	0.7	0.9	-0.1	0.0
Total zone transitions, hab. session 2	0.3	0.4	0.9	0.1	0.3	0.7	-0.9
Total locomotion distance, hab. session 2	0.1	0.1	0.3	0.2	0.3	0.2	-0.6
Locomotion velocity, hab. session 2	0.1	0.1	0.3	-0.1	0.1	0.1	-0.5
Novel to familiar place preference ratio	1.3	1.5	3.1	0.9	0.8	-1.8	1.1
Novelty place preference	1.3	1.4	2.9	0.9	0.9	-1.7	1.0
Time in novel zone, NPP test	1.1	1.2	2.6	0.8	0.8	-1.6	0.9
Total zone transitions, NPP test	1.2	1.8	4.1	-0.3	0.0	2.0	-1.7
Total locomotion distance, NPP test	0.8	1.1	2.0	0.4	0.9	1.3	-1.4
Locomotion velocity, NPP test	0.8	1.1	1.8	0.4	0.9	1.3	-1.3
Intraocular pressure	0.7	1.0	2.3	-1.5	-1.0	-0.2	0.8
Delta distance traveled before/after self-admin	0.3	0.3	0.5	-0.7	-0.7	-0.2	0.0
Delta ambulatory time before/after self-admin	0.6	0.7	1.4	-1.2	-1.1	-0.3	-0.3
Parametrial fat weight	0.1	0.3	1.0	0.0	0.4	-1.0	-0.1
Pavlov. Cond. lever latency	0.2	0.2	0.6	0.5	0.1	0.0	0.8
Pavlov. Cond. magazine entry latency	0.5	0.6	2.1	-0.5	-0.4	-1.4	-0.2
Pavlov. Cond. change in total contacts	0.8	0.8	2.9	-0.1	-0.3	0.6	-1.7
Pavlov. Cond. index score	0.3	0.4	0.7	-0.8	-0.5	-0.5	-0.6
Pavlov. Cond. latency score	0.3	0.3	0.8	-0.6	-0.2	-0.9	-0.3
Pavlov. Cond. lever contacts	0.3	0.4	1.0	-0.7	-0.3	-0.1	-1.0
Pavlov. Cond. magazine entry number	0.3	0.4	1.4	0.1	0.0	1.2	0.2
Pavlov. Cond. intertrial magazine entries	0.5	0.6	1.3	-0.5	-1.2	0.9	0.3
Pavlov. Cond. lever-magazine prob. diff.	0.4	0.5	1.0	-0.9	-0.5	-0.1	-1.0
Pavlov. Cond. response bias	0.7	0.8	1.8	-0.9	-0.8	0.1	-1.3
Pavlov. Cond. lever latency	2.5	3.4	6.7	-1.1	-0.8	2.6	-2.3
Pavlov. Cond. magazine entry latency	0.8	0.9	2.7	-0.1	-0.6	-1.6	0.8
Pavlov. Cond. change in total contacts	0.4	0.6	2.0	-0.0	-0.6	-1.4	0.4
Pavlov. Cond. index score	1.0	1.4	3.7	0.3	-0.4	-1.9	1.2
Pavlov. Cond. latency score	0.7	0.9	2.5	0.3	-0.4	-1.6	0.9
Pavlov. Cond. lever contacts	2.9	4.1	8.4	1.1	0.7	-2.9	2.5
Pavlov. Cond. magazine entry number	0.4	0.6	1.7	-0.1	0.5	1.3	-0.5
Pavlov. Cond. intertrial magazine entries	0.6	0.9	2.2	1.0	1.5	0.1	0.7
Pavlov. Cond. lever-magazine prob. diff.	0.9	1.2	3.5	0.3	-0.3	-1.9	1.1
Pavlov. Cond. response bias	2.6	3.5	8.1	0.9	0.2	-2.8	2.2
Time in closed arm before self-admin	1.4	1.8	3.9	-2.0	-1.8	0.3	-0.1
Time in closed arm after self-admin	1.7	1.8	3.4	-1.7	-1.8	0.5	-1.0
Time in open arm before self-admin	1.0	1.1	1.8	0.8	1.1	-1.0	1.3
Time in open arm after self-admin	1.4	1.5	4.0	2.0	1.4	0.5	0.3
Bone: periosteal estimation	0.5	1.0	1.9	1.4	1.0	-0.6	0.8
Bone: periosteal perimeter	1.0	1.6	2.1	1.5	1.5	-1.0	1.1
Bone: post-yield work	0.7	1.0	2.8	0.2	0.2	1.0	-1.7
Progressive ratio test 1 active lever presses	0.1	0.1	0.2	-0.5	-0.4	-0.2	0.4
Progressive ratio test 1 breakpoint	0.1	0.1	0.2	-0.5	-0.3	-0.1	0.2
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.2	-0.4	-0.4	-0.0	-0.3
Progressive ratio test 2 active lever presses	0.1	0.1	0.3	-0.4	-0.6	0.1	0.3
Progressive ratio test 2 breakpoint	0.1	0.1	0.2	-0.2	-0.4	-0.1	0.4
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.1	0.3	0.1	0.1	0.0
Incentive Sensitization - Responses	0.0	0.1	0.2	0.0	-0.1	0.2	0.5
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	0.0	-0.1	0.1	0.5
Sum of active levers in priming session hrs 5-6	1.2	1.1	2.4	-0.2	-0.5	1.6	-1.4
Progressive ratio	0.1	0.1	0.2	-0.2	-0.5	0.0	-0.2
Food seeking constrained by brief footshock	0.0	0.1	0.2	-0.2	0.0	-0.4	-0.2
Seeking ratio, punishment vs. effort	0.0	0.1	0.1	-0.3	0.0	-0.3	0.1
Retroperitoneal fat weight	2.4	10.1	13.9	3.2	2.8	-3.7	3.0
Reaction time number correct	1.1	2.1	5.8	2.4	1.6	-0.1	0.5
Reaction time mean minus median	0.5	1.2	1.9	1.1	0.9	-1.4	1.0
Reaction time mean minus median AUC	1.2	3.1	3.5	1.9	1.7	-1.8	1.7
Reaction time num false alarms	0.0	0.0	0.1	-0.1	0.1	0.2	-0.3
Reaction time num false alarms AUC	0.1	0.1	0.2	-0.4	-0.4	0.3	-0.4
Reaction time trials correct on left	1.1	2.1	5.8	2.4	1.6	-0.1	0.5
Reaction time trials on left	1.1	2.1	5.7	2.4	1.6	-0.1	0.5
Reaction time mean	0.6	1.0	2.3	-1.2	-1.5	-0.2	-0.5
Reaction time mean AUC	0.3	0.4	1.0	-0.7	-1.0	-0.4	-0.0
Median of all reaction times	1.9	2.7	5.3	-2.0	-2.3	0.5	-1.1
Reaction time omissions	0.8	1.1	2.5	0.7	0.8	-1.6	0.9
Reaction time false alarm rate	0.5	0.7	1.9	-1.4	-0.9	0.1	-0.4
Reaction time premature initiation rate	1.3	1.8	3.3	-1.8	-1.8	-0.5	-0.7
Reaction time premature initiations	0.2	0.4	0.9	-0.5	-0.9	-0.5	-0.4
Std. dev. reaction times	0.8	1.5	3.0	0.8	0.6	-1.7	1.4
Reaction time trials completed	1.1	2.1	5.7	2.4	1.6	-0.1	0.5
Reaction time trials AUC	0.9	1.6	4.8	2.2	1.2	-0.1	0.4
Run reversals in cocaine runway, females	1.0	1.0	1.9	0.6	0.3	1.3	-1.4
Run reversals in cocaine runway, males	1.1	1.1	1.6	-1.1	-0.9	1.3	-0.8
Latency to leave start box in cocaine runway	0.2	0.2	0.5	-0.5	-0.7	-0.4	0.0
Latency to leave start box in cocaine runway, F	0.1	0.1	0.3	-0.6	-0.4	-0.0	-0.1
Latency to leave start box in cocaine runway, M	0.3	0.3	0.7	-0.1	-0.8	-0.7	-0.1
Std. dev. time between licks in bursts	1.9	2.6	3.4	1.6	1.8	-1.3	1.7
Total sessions with >9 infusions	0.6	0.8	2.0	-0.5	0.2	-0.9	1.4
Short access day 1 total inactive lever presses	1.2	1.6	3.4	1.5	1.8	-0.4	0.6
Short access day 10 total inactive lever presses	0.6	1.5	3.4	1.4	0.8	0.3	-1.8
Short access day 1 total infusions	0.1	0.1	0.3	-0.4	0.2	0.2	0.5
Short access day 10 total infusions	0.3	0.4	0.6	-0.5	-0.3	-0.7	0.8
Short access total infusions	0.4	0.5	1.7	-0.3	0.1	-0.5	1.3
Short access day 1 locomotion	0.4	0.5	1.2	-1.1	-0.5	-0.2	0.6
Short access day 10 total locomotion	1.1	1.9	4.7	1.5	2.2	0.0	1.0
Short access total locomotion	1.5	1.8	2.9	0.5	1.4	-1.4	1.7
One hour access (0.3 mA shock)	1.0	1.1	3.2	0.2	-0.7	1.8	-0.9
Compulsive drug intake	0.2	0.2	0.5	0.5	-0.3	0.7	-0.2
One hour access (shock baseline)	0.1	0.1	0.2	-0.5	-0.5	0.1	0.0
Social response proportion	1.0	1.2	2.9	-0.8	-1.7	-0.3	-1.0
Social responses	2.3	3.0	7.2	-2.1	-2.7	-0.2	-0.7
Social time	0.3	0.4	0.9	-0.4	-0.9	-0.4	0.5
Soleus weight	0.1	0.3	0.9	-0.5	-1.0	-0.2	0.3
Bone: stiffness	0.5	0.9	1.6	1.2	0.9	-1.0	0.3
Tibialis anterior weight	0.1	0.3	0.8	-0.0	-0.9	-0.2	0.5
Time to tail flick, vehicle, before self-admin	0.9	0.9	1.7	0.5	0.9	-0.9	1.3
Time to tail flick, vehicle, after self-admin	0.5	0.6	1.8	0.6	0.5	0.0	1.4
Time to tail flick, test, before self-admin	0.4	0.4	1.0	-0.2	0.0	-1.0	0.7
Time to tail flick, test, after self-admin	0.7	0.8	1.3	0.7	0.7	-0.9	1.1
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	1.3	1.1	0.4	0.3	-0.0
Delta time to tail flick, test, before/after SA	0.2	0.2	0.5	0.3	0.2	-0.1	0.7
Tibia length	1.0	2.7	3.8	1.3	1.9	-2.0	1.3
Ambulatory time before self-admin	0.6	0.9	1.1	1.1	1.0	-0.5	1.0
Ambulatory time after self-admin	0.3	0.3	0.7	-0.6	-0.8	0.4	-0.3
Bone: tissue strength	0.4	0.4	0.9	0.7	0.9	0.0	-0.3
Total heroin consumption	0.4	0.5	1.3	-0.1	0.3	1.1	-0.7
Bone: trabecular number	0.8	1.3	3.8	1.9	1.2	0.2	0.0
Bone: trabecular spacing	1.0	1.3	2.3	-1.5	-0.8	-1.2	1.0
Bone: trabecular thickness	0.4	0.5	0.9	-0.3	-0.9	0.9	-0.5
Bone: trabecular tissue density	4.4	6.5	11.1	-1.3	-1.5	3.3	-3.3
Water consumed over 24 hours	0.3	0.4	1.0	-0.7	-1.0	0.2	-0.1
Number of responses in last shaping day	0.3	0.3	0.7	-0.9	-0.4	-0.5	0.3