Hub : Genes

Ilf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc gene expression Ilf2 0.08 0.08 2.1e-07 0.05 0.06 0.07 0.05 2.4e-06 2.3e-07 3.3e-08 1.2e-06
2 PL gene expression Ilf2 0.5 0.28 1.1e-14 0.13 0.13 0.12 0.13 8.7e-14 5.1e-14 5.3e-13 6.3e-14
3 Brain mRNA stability Ilf2 0.08 0.07 3.6e-06 0.09 0.06 0.07 0.08 2.7e-08 4.0e-06 3.2e-07 7.6e-08
4 LHb gene expression Ilf2 0.17 0.14 2.6e-03 0.13 0.1 0.11 0.11 6.0e-04 2.5e-03 1.8e-03 1.3e-03
5 NAcc mRNA stability Ilf2 0.04 0.05 2.1e-04 0.03 0.03 0.03 0.03 7.8e-05 1.2e-04 1.8e-04 9.7e-05
6 Liver gene expression Ilf2 0.13 0.12 9.5e-12 0.08 0.08 0.07 0.07 2.2e-09 1.9e-09 6.0e-08 9.8e-09
7 BLA gene expression Ilf2 0.16 0.13 1.6e-07 0.09 0.12 0.1 0.1 1.7e-05 4.2e-07 4.3e-06 4.1e-06
8 Brain gene expression Ilf2 0.13 0.1 7.3e-12 0.12 0.12 0.12 0.12 2.8e-11 1.7e-11 1.1e-11 1.2e-11
9 Adipose gene expression Ilf2 0.16 0.15 1.3e-12 0.09 0.09 0.08 0.09 2.0e-10 5.2e-10 6.5e-09 3.7e-10
10 Adipose mRNA stability Ilf2 0.4 0.16 0.0e+00 0.35 0.35 0.35 0.35 5.5e-40 8.0e-40 1.1e-39 7.6e-40
11 IL gene expression Ilf2 0.21 0.16 4.8e-04 0.14 0.13 0.14 0.12 2.6e-04 5.0e-04 3.5e-04 6.4e-04
12 PL mRNA stability Ilf2 0.08 0.19 2.8e-04 0.02 0.03 0.02 0.03 1.1e-03 1.8e-04 2.3e-03 2.4e-04
13 Liver mRNA stability Ilf2 0.06 0.06 9.4e-06 0.04 0.04 0.04 0.04 1.1e-05 7.8e-05 3.8e-05 2.7e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.23.01.70.1-0.0-0.0-0.1-0.0-0.0-0.10.20.20.2-0.10.0
Area under the delay curve1.51.62.6-1.01.6-1.3-1.3-1.41.31.3-1.2-1.2-1.2-1.21.2-1.1
BMI with tail0.00.10.2-0.40.2-0.4-0.4-0.40.30.3-0.4-0.4-0.4-0.40.4-0.3
BMI without tail0.20.50.80.3-0.50.60.60.6-0.7-0.80.60.90.90.8-0.80.9
Body weight0.21.02.01.4-1.21.01.01.0-1.0-1.01.00.90.90.8-0.90.8
Weight adjusted by age0.10.10.20.50.1-0.0-0.0-0.40.20.2-0.4-0.4-0.4-0.20.2-0.3
Bone surface0.30.53.41.80.9-0.6-0.6-0.50.50.5-0.5-0.1-0.1-0.10.3-0.3
Bone volume0.30.55.42.30.4-0.3-0.3-0.40.20.2-0.30.00.00.10.1-0.2
Breakpoint value in progressive ratio session2.12.32.8-1.11.7-1.6-1.6-1.51.61.6-1.5-1.5-1.5-1.31.5-1.5
Number of licking bursts0.00.00.1-0.20.2-0.2-0.2-0.30.20.2-0.2-0.2-0.2-0.20.2-0.2
Context. condit. distance diff. score1.01.21.4-0.31.1-1.2-1.2-1.11.11.1-1.1-1.1-1.1-1.01.1-1.1
Locomotion velocity, session 10.91.01.3-0.60.9-1.1-1.1-0.91.01.0-0.9-1.1-1.1-1.11.1-1.1
Locomotion distance, session 11.31.72.10.8-1.31.31.31.4-1.3-1.31.41.41.41.3-1.31.3
Locomotion velocity, session 22.52.97.7-2.81.6-1.6-1.6-1.61.61.6-1.6-1.6-1.6-1.61.5-1.4
Locomotion distance, session 20.20.22.01.4-0.60.30.30.3-0.3-0.30.30.10.10.1-0.20.0
Locomotion velocity, session 30.30.30.40.00.5-0.6-0.6-0.60.60.6-0.6-0.6-0.6-0.60.6-0.6
Locomotion distance, session 30.50.50.7-0.70.8-0.8-0.8-0.80.80.8-0.8-0.6-0.6-0.60.8-0.7
Stereotopy head waving bouts, day 32.73.28.4-2.91.9-1.8-1.8-1.61.71.6-1.6-1.7-1.7-1.61.6-1.4
Stereotopy head waving duration, day 32.83.36.7-2.62.0-1.9-1.9-1.71.81.7-1.7-1.7-1.7-1.61.6-1.4
Locomotion velocity, session 71.92.02.2-1.11.4-1.5-1.5-1.41.51.5-1.4-1.4-1.4-1.51.5-1.5
Locomotion distance, session 70.40.50.9-0.90.7-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.80.7-0.7
Stereotopy head waving bouts, day 70.10.10.8-0.90.1-0.1-0.10.00.10.1-0.0-0.0-0.00.00.00.0
Stereotopy head waving duration, day 70.10.10.5-0.70.5-0.4-0.4-0.20.30.3-0.2-0.2-0.2-0.10.3-0.2
Locomotion velocity, session 83.23.814.9-3.91.9-1.8-1.8-1.71.71.7-1.7-1.7-1.7-1.71.6-1.4
Locomotion distance, session 80.30.40.60.60.5-0.7-0.7-0.60.60.6-0.6-0.6-0.6-0.70.7-0.8
Degree of sensitization distance0.10.11.4-1.2-0.10.10.10.1-0.1-0.10.1-0.0-0.0-0.1-0.10.2
Degree of sensitization stereotypy0.10.10.20.4-0.40.40.40.4-0.3-0.30.40.40.40.4-0.30.3
Conditioned locomotion0.10.10.8-0.9-0.00.20.20.3-0.2-0.20.30.30.30.3-0.30.4
Cocaine response after cond. corrected0.10.10.5-0.7-0.0-0.2-0.2-0.30.20.2-0.4-0.5-0.5-0.50.3-0.4
Cocaine response after cond. not corrected0.20.21.3-1.1-0.1-0.1-0.1-0.20.10.1-0.2-0.5-0.5-0.50.2-0.3
Cocaine response before conditioning0.00.10.5-0.70.10.00.00.3-0.0-0.00.30.20.20.2-0.10.1
Saline control response1.62.02.5-1.21.2-1.4-1.4-1.51.41.4-1.5-1.6-1.6-1.61.4-1.5
Bone: connectivity density0.00.10.20.30.4-0.0-0.0-0.0-0.1-0.10.00.40.40.4-0.20.4
Bone: cortical apparent density0.60.82.91.7-0.1-0.5-0.5-0.50.60.7-0.6-1.0-1.0-1.00.9-1.1
Bone: cortical area0.71.013.33.70.0-0.1-0.1-0.10.10.1-0.00.00.00.00.1-0.4
Bone: cortical porosity0.10.11.51.20.1-0.1-0.1-0.20.20.2-0.2-0.0-0.0-0.00.2-0.3
Bone: cortical porosity0.20.30.70.80.4-0.4-0.4-0.50.50.5-0.5-0.3-0.3-0.30.5-0.7
Bone: cortical thickness0.20.43.01.70.4-0.4-0.4-0.40.40.4-0.4-0.3-0.3-0.30.4-0.6
Bone: cortical thickness0.20.20.40.6-0.60.50.50.5-0.5-0.50.50.40.40.4-0.40.3
Bone: cortical tissue density0.50.72.21.5-0.1-0.5-0.5-0.50.60.6-0.6-1.0-1.0-1.00.8-1.1
Condit. Reinf. active minus inactive responses1.82.02.5-0.5-1.41.51.51.5-1.5-1.51.51.41.41.4-1.51.6
Condit. Reinf. active-inactive response ratio2.93.14.3-0.6-1.41.71.71.8-1.8-1.81.81.91.91.9-1.92.1
Condit. Reinf. active responses2.32.83.81.1-2.01.81.81.8-1.8-1.81.71.61.61.5-1.71.6
Condit. Reinf. inactive responses0.50.64.62.1-1.00.60.60.5-0.4-0.40.40.10.10.1-0.2-0.1
Incentive salience index mean1.92.32.90.9-1.71.61.61.6-1.6-1.61.61.41.41.4-1.51.4
Condit. Reinf. lever presses2.43.214.53.8-1.91.61.61.7-1.5-1.51.61.41.41.3-1.31.0
Condit. Reinf. active minus inactive responses0.60.71.2-1.01.1-1.0-1.0-0.70.90.9-0.7-0.7-0.7-0.70.8-0.6
Condit. Reinf. active-inactive response ratio0.60.61.4-0.91.2-0.9-0.9-0.80.80.8-0.7-0.5-0.5-0.50.7-0.5
Condit. Reinf. active responses0.40.61.3-1.20.9-0.9-0.9-0.60.80.8-0.6-0.8-0.8-0.80.7-0.6
Condit. Reinf. inactive responses1.01.21.9-0.40.7-1.0-1.0-0.91.11.1-1.0-1.4-1.4-1.41.2-1.3
Condit. Reinf. lever presses0.30.30.60.70.2-0.5-0.5-0.30.50.5-0.4-0.7-0.7-0.70.6-0.7
Condit. Reinf. lever reinforcers received0.40.52.2-1.50.8-0.7-0.7-0.40.60.6-0.5-0.7-0.7-0.70.6-0.5
Conditioned reinforcement - actives0.40.41.61.3-0.70.50.50.6-0.5-0.50.60.60.60.6-0.40.3
Conditioned reinforcement - inactives0.70.85.1-2.30.7-0.6-0.6-0.70.70.7-0.7-0.7-0.7-0.70.7-0.6
Conditioned locomotion0.60.78.2-2.90.3-0.3-0.3-0.30.30.3-0.3-0.3-0.3-0.30.3-0.2
Patch foraging indifference point 0 sec0.91.51.8-0.71.2-1.2-1.2-1.21.21.2-1.2-1.4-1.4-1.31.2-1.1
Patch foraging indifference point AUC0.10.10.30.5-0.10.10.10.4-0.3-0.30.40.40.40.3-0.40.3
Delay disc. indifference point, 0s delay1.51.62.3-0.31.5-1.3-1.3-1.41.31.3-1.3-1.3-1.3-1.31.3-1.2
Delay disc. indifference point, 16s delay0.30.30.6-0.70.8-0.6-0.6-0.50.50.5-0.5-0.4-0.4-0.50.4-0.3
Delay disc. indifference point, 2s delay0.50.51.9-1.40.8-0.7-0.7-0.70.70.7-0.6-0.6-0.6-0.70.6-0.4
Delay disc. indifference point, 24s delay4.03.94.50.42.1-2.1-2.1-2.02.12.1-2.0-1.9-1.9-1.92.0-2.1
Delay disc. indifference point, 4s delay0.10.11.31.10.4-0.2-0.2-0.30.20.2-0.2-0.0-0.0-0.10.1-0.1
Delay disc. indifference point, 8s delay1.01.01.7-0.21.3-1.1-1.1-1.11.11.1-1.0-1.0-1.0-1.01.0-0.9
Indifference point function ln k0.10.10.20.50.3-0.1-0.1-0.30.30.3-0.3-0.2-0.2-0.20.3-0.3
Indifference point function log k0.10.10.20.50.3-0.1-0.1-0.30.30.3-0.3-0.2-0.2-0.20.3-0.3
Patch foraging total patch changes 0 sec0.50.81.2-0.10.9-0.9-0.9-0.90.90.9-0.9-1.1-1.1-1.10.9-0.9
Patch foraging total patch changes 12 sec0.50.77.72.80.1-0.2-0.2-0.30.30.2-0.3-0.2-0.2-0.20.3-0.5
Patch foraging total patch changes 18 sec0.10.11.11.0-0.0-0.0-0.00.1-0.0-0.00.1-0.1-0.1-0.1-0.0-0.1
Patch foraging total patch changes 24 sec0.20.22.1-1.4-0.30.20.20.2-0.2-0.20.1-0.0-0.00.0-0.20.3
Patch foraging total patch changes 6 sec0.30.41.51.20.5-0.8-0.8-0.60.50.5-0.6-0.6-0.6-0.60.5-0.6
Patch foraging time to switch 0 sec0.20.33.92.0-0.1-0.1-0.1-0.20.10.2-0.2-0.1-0.1-0.10.2-0.4
Patch foraging water rate 0 sec0.20.31.0-1.0-0.20.50.50.5-0.5-0.50.50.40.40.4-0.60.7
Patch foraging water rate 12 sec0.10.10.7-0.80.4-0.2-0.2-0.40.20.2-0.4-0.4-0.4-0.30.2-0.0
Patch foraging water rate 18 sec0.30.44.6-2.10.20.10.10.0-0.2-0.20.10.10.10.2-0.30.6
Patch foraging water rate 24 sec1.31.82.30.8-1.21.31.31.4-1.4-1.51.41.31.31.4-1.51.5
Patch foraging water rate 6 sec0.10.20.60.8-0.50.50.50.3-0.4-0.40.30.20.20.2-0.30.2
Seeking ratio, delayed vs. immediate footshock0.40.44.0-2.00.2-0.3-0.3-0.30.30.3-0.4-0.4-0.4-0.50.4-0.2
Distance traveled before self-admin1.92.05.12.3-1.51.31.31.4-1.3-1.31.41.41.41.3-1.21.1
Distance traveled after self-admin1.21.35.62.4-1.11.11.11.0-1.0-1.01.01.01.00.9-0.90.7
Extensor digitorum longus weight1.24.87.32.7-2.12.22.22.1-2.2-2.22.12.22.22.2-2.22.0
Bone: elastic displacement0.30.32.31.5-0.80.50.50.4-0.3-0.30.40.10.10.1-0.2-0.1
Bone: elastic work0.50.76.02.5-0.70.50.50.6-0.5-0.50.50.40.40.3-0.40.1
Bone: endosteal estimation0.41.012.13.5-0.30.10.10.1-0.1-0.10.10.10.10.1-0.0-0.2
Bone: endosteal perimeter0.30.66.22.5-0.0-0.3-0.3-0.30.30.3-0.3-0.4-0.4-0.30.4-0.6
Epididymis fat weight0.20.52.81.7-0.50.50.50.7-0.5-0.50.70.70.70.7-0.50.4
Delta time in closed arm before/after self-admin0.60.62.81.7-0.90.70.70.7-0.6-0.60.70.70.70.5-0.50.3
Delta time in open arm before/after self-admin0.60.67.3-2.70.3-0.1-0.1-0.10.20.2-0.1-0.2-0.2-0.10.10.2
Diff in mean of infusions in LGA sessions0.20.20.50.70.2-0.3-0.3-0.40.30.3-0.4-0.4-0.4-0.30.4-0.5
Delay discount exponential model param1.41.52.50.6-1.61.31.31.3-1.3-1.31.21.21.21.2-1.21.1
Extinction: sum of active levers before priming0.50.50.80.40.6-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.70.7-0.9
Active lever presses in extinction session 62.12.12.3-1.11.5-1.5-1.5-1.51.41.4-1.5-1.5-1.5-1.41.4-1.4
Bone: final force1.93.035.66.0-1.00.60.60.6-0.5-0.50.60.50.50.5-0.4-0.0
Bone: final moment1.93.132.85.7-1.20.80.80.8-0.8-0.80.80.70.70.7-0.70.2
Food consumed during 24 hour testing period0.20.20.20.20.5-0.5-0.5-0.50.50.5-0.5-0.5-0.5-0.50.5-0.4
Glucose0.40.60.8-0.90.8-0.8-0.8-0.70.70.7-0.7-0.7-0.7-0.70.7-0.7
Heart weight0.70.93.31.80.7-0.8-0.8-0.71.01.0-0.7-0.7-0.7-0.71.1-1.3
Delay discount hyperbolic model param1.31.42.30.7-1.51.31.31.3-1.3-1.21.21.11.11.2-1.11.0
Intermittent access intake day 1-15 change0.60.55.12.30.4-0.4-0.4-0.30.40.4-0.3-0.3-0.3-0.30.4-0.6
Intermittent access intake escalation0.40.42.21.50.6-0.6-0.6-0.40.60.6-0.4-0.4-0.4-0.40.6-0.7
Intermittent access intake escalation 21.01.06.42.5-0.70.70.70.9-0.7-0.70.80.90.90.9-0.70.5
Intermitt. access day 1 inactive lever presses0.10.11.1-1.10.1-0.1-0.1-0.30.10.1-0.3-0.3-0.3-0.30.1-0.1
Intermitt. access day 15 inactive lever presses0.80.93.51.90.5-0.7-0.7-0.90.80.8-0.9-0.9-0.9-0.90.9-1.2
Intermitt. access escalation Index1.11.04.3-2.1-0.40.70.70.9-0.8-0.80.90.90.90.9-0.91.1
Intermittent access day 1 total infusions0.20.21.2-1.10.2-0.3-0.3-0.40.40.4-0.4-0.4-0.4-0.40.4-0.4
Intermittent access day 15 total infusions0.50.50.80.10.7-0.7-0.7-0.80.80.8-0.7-0.7-0.7-0.80.8-0.9
Intermittent access terminal intake (last 3 days)0.10.10.30.50.1-0.2-0.2-0.20.20.2-0.2-0.2-0.2-0.20.3-0.4
Intermittent access total infusions0.00.10.10.20.2-0.2-0.2-0.20.30.2-0.2-0.2-0.2-0.20.3-0.3
Intermittent access day 1 locomotion0.70.85.7-2.40.5-0.6-0.6-0.70.60.6-0.7-0.7-0.7-0.60.6-0.5
Intermittent access day 15 total locomotion2.83.06.4-2.51.5-1.6-1.6-1.81.61.6-1.7-1.8-1.8-1.71.6-1.6
Intermittent access total locomotion2.32.77.4-2.71.3-1.5-1.5-1.61.51.5-1.6-1.6-1.6-1.51.5-1.4
Intermittent access standard deviation0.30.34.02.0-0.20.10.10.2-0.0-0.00.10.20.20.1-0.0-0.2
Left kidney weight0.20.66.42.50.0-0.3-0.3-0.10.40.4-0.2-0.4-0.4-0.40.5-0.7
Right kidney weight0.30.86.72.60.0-0.5-0.5-0.40.50.5-0.4-0.5-0.5-0.60.7-0.9
Cocaine induced anxiety0.40.50.7-0.80.7-0.7-0.7-0.70.70.7-0.7-0.6-0.6-0.60.7-0.6
Post-drug Anxiety0.10.20.20.30.3-0.4-0.4-0.40.40.4-0.4-0.4-0.4-0.40.4-0.5
Baseline Anxiety0.30.33.61.9-0.0-0.1-0.1-0.20.20.2-0.2-0.2-0.2-0.20.2-0.5
Tail length0.72.23.01.7-1.41.41.41.5-1.5-1.51.51.61.61.5-1.51.4
Length with tail0.51.83.41.8-1.51.41.41.5-1.3-1.31.41.21.21.1-1.21.0
Length without tail0.10.22.01.4-0.50.20.20.3-0.1-0.10.3-0.0-0.0-0.00.0-0.2
Times rat made contact with spout1.41.61.90.91.3-1.3-1.3-1.31.31.3-1.3-1.1-1.1-1.11.3-1.4
Lifetime Intake0.00.00.0-0.1-0.10.10.10.1-0.0-0.00.10.10.10.1-0.00.0
Liver weight, left1.01.64.6-2.11.1-1.2-1.2-1.01.21.2-1.1-1.2-1.2-1.21.1-1.0
Liver weight, right0.00.00.1-0.00.2-0.1-0.10.00.10.10.00.10.10.10.00.1
Locomotor activity0.81.24.82.2-1.21.01.01.1-1.0-1.01.00.80.80.8-0.90.7
Locomotor testing distance0.20.44.52.1-0.50.10.10.1-0.1-0.00.0-0.2-0.2-0.20.1-0.3
Locomotor testing rearing0.71.11.41.10.9-1.1-1.1-1.01.01.0-1.0-1.0-1.0-0.91.1-1.2
Locomotion in novel chamber0.70.95.4-2.30.9-0.8-0.8-0.80.70.7-0.7-0.7-0.7-0.80.6-0.5
Locomotion in novel chamber post-restriction0.00.00.10.30.2-0.2-0.2-0.20.20.2-0.2-0.1-0.1-0.00.2-0.2
Fecal boli incidents, locomotor time 10.20.21.1-1.0-0.10.20.20.2-0.3-0.40.30.50.50.5-0.40.7
Change in fecal boli incidents, locomotor task0.30.30.50.50.4-0.4-0.4-0.50.50.5-0.5-0.7-0.7-0.70.5-0.6
Time >=10cm from walls, locomotor time 10.50.51.8-1.30.7-0.5-0.5-0.70.60.6-0.6-0.7-0.7-0.60.6-0.4
Bouts of movement, locomotor time 10.40.40.9-1.00.8-0.8-0.8-0.50.60.6-0.5-0.6-0.6-0.50.6-0.4
Total resting periods, locomotor time 10.00.00.4-0.60.2-0.2-0.20.1-0.1-0.10.20.10.10.2-0.10.3
Rest time, locomotor task time 10.10.10.40.60.00.00.00.1-0.2-0.20.20.30.30.4-0.30.2
Distance moved, locomotor task time 10.10.11.0-1.0-0.40.40.40.3-0.2-0.20.30.10.10.1-0.10.1
Vertical activity count, locomotor time 11.51.52.10.8-1.41.51.51.3-1.2-1.21.31.11.11.1-1.21.2
Time >=10cm from walls, locomotor time 22.42.63.9-1.3-1.42.02.01.5-1.6-1.61.51.51.51.5-1.61.8
Bouts of movement, locomotor time 22.32.44.6-2.11.2-1.6-1.6-1.41.41.5-1.4-1.6-1.6-1.61.5-1.5
Total resting periods, locomotor time 22.42.64.1-2.01.3-1.7-1.7-1.41.51.5-1.5-1.6-1.6-1.71.6-1.6
Rest time, locomotor task time 20.50.64.92.2-0.40.20.20.5-0.4-0.50.50.60.60.7-0.50.4
Distance moved, locomotor task time 20.70.910.9-3.30.20.20.2-0.10.10.1-0.1-0.0-0.0-0.00.00.2
Vertical activity count, locomotor time 20.70.81.8-1.3-0.51.01.00.7-0.8-0.80.70.80.80.8-0.91.0
Light reinforcement 10.71.31.6-0.51.2-1.3-1.3-1.21.11.1-1.2-1.2-1.2-1.21.1-1.1
Light reinforcement 21.72.25.6-2.41.5-1.4-1.4-1.41.41.4-1.3-1.5-1.5-1.51.4-1.2
Bone: marrow area0.40.912.13.5-0.30.10.10.1-0.0-0.00.10.10.10.10.0-0.3
Bone: maximum diameter0.81.53.41.91.1-1.2-1.2-1.21.21.2-1.2-1.0-1.0-1.01.2-1.3
Bone: maximum force2.13.742.56.5-1.20.70.70.7-0.7-0.60.70.50.50.5-0.5-0.1
Bone: maximum moment2.03.537.06.1-1.40.90.90.9-0.8-0.80.80.60.60.6-0.60.1
Mean time between licks in bursts1.72.43.10.7-1.81.71.71.6-1.7-1.71.51.61.61.6-1.61.5
Mean num. licks in bursts0.30.41.11.10.6-0.6-0.6-0.50.60.6-0.5-0.5-0.5-0.50.6-0.7
Cd content in liver5.45.914.73.8-2.52.32.32.3-2.3-2.32.32.22.22.2-2.21.9
Co content in liver0.10.10.50.2-0.70.40.40.4-0.3-0.30.3-0.1-0.1-0.1-0.2-0.0
Cu content in liver0.81.03.3-1.8-0.60.90.90.8-0.9-0.90.80.90.90.9-1.01.2
Fe content in liver1.31.62.31.5-1.21.21.21.2-1.2-1.21.31.31.31.3-1.21.2
K content in liver0.10.10.2-0.40.2-0.2-0.2-0.30.20.2-0.2-0.3-0.3-0.30.3-0.2
Mg content in liver0.70.70.9-1.00.8-0.8-0.8-0.90.80.8-0.8-0.9-0.9-0.90.8-0.8
Mn content in liver0.20.30.9-1.00.4-0.4-0.4-0.50.40.4-0.4-0.6-0.6-0.60.4-0.3
Na content in liver1.11.25.2-2.31.3-1.1-1.1-1.00.90.9-0.9-0.8-0.8-0.80.8-0.5
Rb content in liver0.10.10.20.2-0.10.30.30.2-0.3-0.30.30.30.30.3-0.40.5
Se content in liver0.30.32.2-1.50.1-0.3-0.3-0.30.40.4-0.3-0.6-0.6-0.70.5-0.4
Sr content in liver1.21.16.62.6-1.30.90.90.9-0.8-0.80.90.50.50.5-0.60.4
Zn content in liver0.40.45.5-2.30.1-0.0-0.0-0.10.10.1-0.0-0.3-0.3-0.30.1-0.1
Bone: minimum diameter0.71.413.53.70.4-0.6-0.6-0.50.60.6-0.5-0.5-0.5-0.50.6-0.9
Time in familiar zone, hab. session 10.30.31.1-1.00.5-0.5-0.5-0.30.50.4-0.3-0.4-0.4-0.50.4-0.4
Time in novel zone, hab. session 10.50.51.81.4-0.80.70.70.6-0.7-0.60.50.60.60.5-0.60.5
Total zone transitions, hab. session 10.20.32.71.6-0.40.30.30.3-0.3-0.30.30.50.50.4-0.20.1
Total locomotion distance, hab. session 10.10.11.21.1-0.2-0.1-0.10.00.10.1-0.0-0.1-0.1-0.20.2-0.4
Locomotion velocity, hab. session 10.10.21.41.2-0.1-0.2-0.2-0.10.30.3-0.2-0.3-0.3-0.40.4-0.6
Time in familiar zone, hab. session 20.20.20.70.6-0.80.50.50.4-0.4-0.40.40.10.10.1-0.30.1
Time in novel zone, hab. session 20.20.20.4-0.50.00.30.30.3-0.4-0.40.40.60.60.6-0.50.7
Total zone transitions, hab. session 20.30.42.71.6-0.50.30.30.5-0.3-0.30.50.40.40.4-0.30.2
Total locomotion distance, hab. session 20.10.10.20.40.0-0.2-0.2-0.10.20.2-0.1-0.3-0.3-0.30.3-0.4
Locomotion velocity, hab. session 20.10.10.40.6-0.0-0.2-0.2-0.00.20.2-0.1-0.3-0.3-0.30.3-0.4
Novel to familiar place preference ratio1.11.17.42.7-0.30.50.50.6-0.6-0.60.71.11.11.1-0.70.7
Novelty place preference0.90.96.52.6-0.20.40.40.5-0.5-0.50.60.90.91.0-0.60.6
Time in novel zone, NPP test0.70.74.82.2-0.10.40.40.5-0.5-0.50.60.90.90.9-0.60.6
Total zone transitions, NPP test0.00.00.1-0.2-0.1-0.0-0.00.1-0.0-0.00.10.10.10.0-0.00.0
Total locomotion distance, NPP test0.10.20.3-0.00.4-0.5-0.5-0.40.50.5-0.4-0.4-0.4-0.50.5-0.5
Locomotion velocity, NPP test0.10.10.20.40.2-0.4-0.4-0.20.30.3-0.2-0.3-0.3-0.40.4-0.4
Intraocular pressure0.81.28.02.80.5-0.7-0.7-0.60.80.8-0.7-0.7-0.7-0.80.9-1.1
Delta distance traveled before/after self-admin0.10.10.20.4-0.30.30.30.2-0.2-0.20.20.30.30.2-0.20.2
Delta ambulatory time before/after self-admin0.00.00.10.30.00.10.1-0.00.00.0-0.00.00.0-0.10.0-0.1
Parametrial fat weight0.10.20.70.8-0.50.50.50.3-0.5-0.50.40.30.30.4-0.50.5
Pavlov. Cond. lever latency4.86.127.7-5.32.6-2.2-2.2-2.22.12.1-2.1-1.9-1.9-1.91.9-1.5
Pavlov. Cond. magazine entry latency8.310.637.36.1-3.53.13.13.0-2.9-2.92.92.82.82.7-2.72.3
Pavlov. Cond. change in total contacts4.54.920.04.5-2.32.02.02.0-1.9-1.91.91.81.81.8-1.81.4
Pavlov. Cond. index score7.49.443.26.6-3.12.72.72.7-2.6-2.62.62.52.52.5-2.41.9
Pavlov. Cond. latency score7.39.239.26.3-3.22.82.82.7-2.6-2.62.62.52.52.5-2.42.0
Pavlov. Cond. lever contacts6.37.443.76.6-2.72.22.22.2-2.1-2.12.12.02.01.9-1.91.4
Pavlov. Cond. magazine entry number8.410.453.3-7.33.2-2.8-2.8-2.72.62.6-2.6-2.5-2.5-2.52.4-1.9
Pavlov. Cond. intertrial magazine entries1.11.316.3-4.00.00.20.20.2-0.3-0.30.20.10.10.2-0.40.7
Pavlov. Cond. lever-magazine prob. diff.7.18.844.16.6-3.02.62.62.5-2.4-2.42.42.32.32.3-2.21.7
Pavlov. Cond. response bias8.510.350.37.1-3.22.82.82.7-2.6-2.62.62.52.52.5-2.41.9
Pavlov. Cond. lever latency1.52.12.8-1.41.7-1.5-1.5-1.61.51.5-1.5-1.3-1.3-1.31.4-1.3
Pavlov. Cond. magazine entry latency1.41.62.90.9-1.71.41.41.3-1.4-1.31.31.01.01.0-1.21.1
Pavlov. Cond. change in total contacts0.20.20.5-0.1-0.70.50.50.6-0.5-0.50.60.20.20.2-0.40.3
Pavlov. Cond. index score1.62.13.20.5-1.81.61.61.6-1.6-1.61.61.31.31.3-1.51.4
Pavlov. Cond. latency score2.02.53.60.3-1.91.71.71.7-1.7-1.71.71.41.41.4-1.61.5
Pavlov. Cond. lever contacts1.21.72.51.4-1.61.31.31.4-1.3-1.31.41.11.11.1-1.21.1
Pavlov. Cond. magazine entry number1.41.72.8-0.51.7-1.5-1.5-1.41.41.4-1.4-1.1-1.1-1.11.3-1.3
Pavlov. Cond. intertrial magazine entries1.21.62.7-0.81.7-1.4-1.4-1.31.41.3-1.3-1.1-1.1-1.11.3-1.2
Pavlov. Cond. lever-magazine prob. diff.1.51.93.00.5-1.71.51.51.6-1.5-1.51.51.21.21.2-1.41.3
Pavlov. Cond. response bias1.11.52.61.2-1.61.31.31.4-1.3-1.21.31.01.01.0-1.11.0
Time in closed arm before self-admin0.30.32.2-1.50.8-0.5-0.5-0.40.30.3-0.3-0.2-0.2-0.10.10.2
Time in closed arm after self-admin0.40.40.7-0.30.8-0.7-0.7-0.60.60.6-0.6-0.5-0.5-0.60.6-0.4
Time in open arm before self-admin4.75.110.33.2-2.52.22.22.2-2.2-2.22.12.12.12.0-2.11.8
Time in open arm after self-admin1.31.41.8-0.7-1.41.31.31.2-1.2-1.21.21.11.11.1-1.11.2
Bone: periosteal estimation0.61.315.53.90.2-0.3-0.3-0.30.30.3-0.3-0.2-0.2-0.20.3-0.6
Bone: periosteal perimeter0.61.07.22.70.6-0.7-0.7-0.70.70.7-0.7-0.7-0.7-0.70.8-1.0
Bone: post-yield work0.50.78.12.9-0.60.30.30.3-0.3-0.30.30.20.20.2-0.30.1
Progressive ratio test 1 active lever presses0.60.72.6-1.60.6-0.7-0.7-0.80.70.7-0.7-0.8-0.8-0.80.7-0.7
Progressive ratio test 1 breakpoint0.40.52.4-1.60.4-0.5-0.5-0.60.50.5-0.6-0.6-0.6-0.60.6-0.5
Progressive ratio test 1 inactive lever presses0.10.11.0-1.0-0.20.30.30.1-0.3-0.40.10.10.10.3-0.40.3
Progressive ratio test 2 active lever presses0.60.73.5-1.90.8-0.7-0.7-0.60.70.7-0.6-0.6-0.6-0.60.7-0.6
Progressive ratio test 2 breakpoint0.50.61.7-1.30.8-0.8-0.8-0.70.70.7-0.7-0.6-0.6-0.60.7-0.7
Progressive ratio test 2 inactive lever presses1.82.14.6-2.11.3-1.3-1.3-1.51.31.3-1.4-1.5-1.5-1.41.3-1.3
Incentive Sensitization - Responses0.00.10.4-0.70.4-0.2-0.20.00.10.1-0.00.00.00.10.00.0
Incentive Sensitization - Breakpoint0.10.10.5-0.70.5-0.3-0.3-0.10.30.3-0.1-0.1-0.1-0.00.2-0.1
Sum of active levers in priming session hrs 5-61.21.11.40.41.1-1.2-1.2-1.11.11.1-1.1-1.1-1.1-0.91.1-1.2
Progressive ratio2.42.714.9-3.91.1-1.1-1.1-1.41.31.3-1.4-1.4-1.4-1.61.4-1.2
Food seeking constrained by brief footshock0.50.62.1-1.40.8-0.8-0.8-0.60.70.7-0.6-0.6-0.6-0.70.7-0.6
Seeking ratio, punishment vs. effort0.60.74.82.2-0.30.40.40.7-0.5-0.60.70.80.80.8-0.60.6
Retroperitoneal fat weight0.72.22.60.0-1.51.51.51.6-1.5-1.51.61.61.61.5-1.51.6
Reaction time number correct0.71.02.9-1.71.1-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.90.8-0.6
Reaction time mean minus median0.20.32.9-1.7-0.00.10.10.2-0.2-0.30.20.30.30.3-0.30.3
Reaction time mean minus median AUC0.20.31.7-1.3-0.00.30.30.3-0.4-0.40.40.50.50.5-0.50.5
Reaction time num false alarms0.10.20.3-0.3-0.60.50.50.4-0.4-0.40.40.30.30.3-0.30.4
Reaction time num false alarms AUC0.10.10.6-0.8-0.60.40.40.3-0.3-0.20.30.10.10.1-0.20.2
Reaction time trials correct on left0.71.02.9-1.71.1-0.9-0.9-0.90.90.9-0.9-0.9-0.9-0.90.8-0.6
Reaction time trials on left0.71.03.1-1.81.2-0.9-0.9-0.90.90.9-0.9-0.9-0.9-1.00.8-0.6
Reaction time mean0.30.44.0-2.00.5-0.2-0.2-0.30.20.1-0.2-0.1-0.1-0.10.1-0.0
Reaction time mean AUC0.30.44.8-2.20.3-0.0-0.0-0.1-0.1-0.10.00.10.10.1-0.20.3
Median of all reaction times0.10.11.3-1.20.3-0.2-0.2-0.20.10.1-0.2-0.1-0.1-0.10.1-0.0
Reaction time omissions0.20.21.2-1.1-0.20.30.30.3-0.4-0.40.40.20.20.3-0.50.6
Reaction time false alarm rate0.40.51.30.3-1.10.90.90.8-0.8-0.70.80.60.60.6-0.60.5
Reaction time premature initiation rate1.82.427.45.20.0-0.6-0.6-0.20.50.5-0.3-0.5-0.5-0.40.7-1.0
Reaction time premature initiations1.31.818.24.30.3-0.8-0.8-0.30.70.7-0.4-0.6-0.6-0.60.8-1.0
Std. dev. reaction times0.40.55.4-2.30.10.20.20.3-0.3-0.30.30.40.40.4-0.40.6
Reaction time trials completed0.71.03.1-1.81.2-0.9-0.9-0.90.90.9-0.9-0.9-0.9-1.00.8-0.6
Reaction time trials AUC0.81.12.8-1.71.2-1.0-1.0-1.01.01.0-1.0-1.0-1.0-1.00.9-0.7
Run reversals in cocaine runway, females1.51.51.8-0.81.2-1.3-1.3-1.21.31.3-1.2-1.2-1.2-1.31.3-1.2
Run reversals in cocaine runway, males0.60.66.6-2.6-0.20.30.30.3-0.4-0.30.30.30.30.3-0.40.6
Latency to leave start box in cocaine runway1.92.18.3-2.91.5-1.4-1.4-1.21.31.3-1.2-1.2-1.2-1.21.2-0.9
Latency to leave start box in cocaine runway, F0.10.11.4-1.20.1-0.1-0.10.1-0.0-0.00.10.20.20.2-0.10.3
Latency to leave start box in cocaine runway, M5.85.614.2-3.82.3-2.2-2.2-2.22.22.2-2.2-2.3-2.3-2.22.1-1.9
Std. dev. time between licks in bursts0.10.10.80.9-0.50.30.30.2-0.2-0.20.20.20.20.2-0.1-0.0
Total sessions with >9 infusions0.10.10.2-0.40.3-0.4-0.4-0.30.30.3-0.3-0.3-0.3-0.20.3-0.3
Short access day 1 total inactive lever presses0.00.00.1-0.30.1-0.1-0.1-0.20.10.1-0.2-0.2-0.2-0.10.1-0.0
Short access day 10 total inactive lever presses0.10.10.10.3-0.20.30.30.2-0.3-0.30.20.20.20.3-0.30.2
Short access day 1 total infusions0.40.41.91.4-0.60.60.60.6-0.5-0.50.60.50.50.6-0.50.5
Short access day 10 total infusions0.30.44.2-2.00.3-0.2-0.2-0.20.30.3-0.2-0.3-0.3-0.20.3-0.2
Short access total infusions0.00.00.1-0.3-0.00.00.00.1-0.0-0.00.10.10.10.1-0.00.1
Short access day 1 locomotion0.20.20.7-0.80.4-0.4-0.4-0.30.30.3-0.4-0.4-0.4-0.30.3-0.4
Short access day 10 total locomotion1.71.93.9-2.01.3-1.4-1.4-1.31.31.3-1.3-1.3-1.3-1.31.3-1.1
Short access total locomotion0.80.81.9-1.40.8-0.9-0.9-0.80.90.9-0.9-0.9-0.9-0.80.9-0.9
One hour access (0.3 mA shock)0.10.10.30.5-0.30.30.30.5-0.3-0.30.40.50.50.4-0.30.2
Compulsive drug intake0.80.81.30.2-0.90.90.90.9-1.0-1.00.90.90.90.9-0.91.1
One hour access (shock baseline)0.10.10.6-0.80.4-0.3-0.3-0.20.30.3-0.2-0.2-0.2-0.20.3-0.4
Social response proportion0.91.012.2-3.50.6-0.3-0.3-0.30.10.1-0.2-0.1-0.1-0.0-0.10.4
Social responses0.60.82.9-1.71.1-1.0-1.0-0.80.80.8-0.7-0.7-0.7-0.60.7-0.6
Social time1.31.76.1-2.51.5-1.3-1.3-1.31.21.2-1.2-1.1-1.1-1.01.0-0.9
Soleus weight0.20.61.20.40.5-0.7-0.7-0.80.80.8-0.8-0.9-0.9-1.00.9-1.1
Bone: stiffness0.91.519.04.4-0.2-0.0-0.0-0.00.10.1-0.00.10.10.10.1-0.4
Tibialis anterior weight0.00.10.4-0.7-0.20.30.30.2-0.3-0.30.20.20.20.2-0.30.3
Time to tail flick, vehicle, before self-admin2.82.83.5-1.31.6-1.6-1.6-1.61.71.8-1.7-1.7-1.7-1.81.8-1.9
Time to tail flick, vehicle, after self-admin1.92.13.7-1.91.3-1.4-1.4-1.41.41.4-1.4-1.3-1.3-1.41.5-1.3
Time to tail flick, test, before self-admin3.13.05.2-2.31.8-1.6-1.6-1.71.71.7-1.7-1.8-1.8-1.61.6-1.4
Time to tail flick, test, after self-admin0.00.00.50.7-0.1-0.0-0.00.10.00.00.00.10.1-0.10.1-0.1
Delta time to tail flick, vehicle, before/after SA0.10.10.7-0.90.3-0.3-0.3-0.20.20.2-0.2-0.1-0.1-0.10.1-0.0
Delta time to tail flick, test, before/after SA1.41.34.52.1-1.10.90.91.1-1.0-1.01.01.21.21.0-0.90.8
Tibia length0.41.21.80.10.9-1.1-1.1-1.11.11.1-1.1-1.3-1.3-1.31.1-1.2
Ambulatory time before self-admin2.12.12.41.0-1.51.51.51.5-1.5-1.51.51.51.51.5-1.51.5
Ambulatory time after self-admin1.31.45.62.4-1.11.11.11.0-1.0-1.01.01.11.11.0-0.90.8
Bone: tissue strength0.40.30.40.5-0.60.60.60.6-0.6-0.60.60.60.60.6-0.60.6
Total heroin consumption0.91.11.4-0.81.2-1.2-1.2-1.01.11.1-1.0-1.0-1.0-0.91.0-0.9
Bone: trabecular number0.20.42.11.5-0.20.40.40.3-0.4-0.40.30.60.60.6-0.50.5
Bone: trabecular spacing0.60.71.3-0.40.2-0.6-0.6-0.70.80.8-0.8-1.1-1.1-1.11.0-1.1
Bone: trabecular thickness0.30.30.70.80.6-0.6-0.6-0.60.60.6-0.6-0.4-0.4-0.40.5-0.6
Bone: trabecular tissue density0.20.20.60.80.4-0.5-0.5-0.30.50.5-0.3-0.4-0.4-0.40.5-0.6
Water consumed over 24 hours0.70.81.40.11.2-1.0-1.0-0.91.01.0-0.9-0.8-0.8-0.80.9-0.8
Number of responses in last shaping day0.40.40.60.7-0.50.60.60.6-0.7-0.70.60.60.60.8-0.80.7