Il18bp

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression Il18bp 0.11 0.08 7.5e-04 0.05 0.04 0.05 0.02 7.3e-04 2.0e-03 1.0e-03 3.3e-02
2 Brain gene expression Il18bp 0.17 0.1 4.2e-11 0.1 0.11 0.1 0.11 2.8e-09 2.4e-10 6.1e-10 3.6e-10
3 Liver gene expression Il18bp 0.28 0.14 0.0e+00 0.16 0.16 0.16 0.16 2.6e-17 1.0e-17 2.3e-17 1.8e-17
4 Adipose mRNA stability Il18bp 0.17 0.1 4.0e-15 0.11 0.1 0.11 0.1 5.8e-12 1.0e-11 7.7e-12 1.6e-11
5 NAcc gene expression Il18bp 0.09 0.06 3.1e-07 0.06 0.06 0.05 0.06 1.5e-07 2.4e-07 1.6e-06 4.9e-07
6 Liver intron excision ratio chr1_156374242_156374489 0.04 0.03 2.7e-03 0.02 0.01 0.01 0.01 5.9e-03 1.7e-02 6.7e-03 1.1e-02
7 NAcc intron excision ratio chr1_156374242_156374489 0.02 0.02 9.1e-03 0.01 0.01 0.01 0.01 8.7e-03 1.2e-02 5.9e-02 2.3e-02
8 Liver intron excision ratio chr1_156373709_156374048 0.05 0.04 3.9e-04 0.03 0.02 0.03 0.02 6.6e-04 1.4e-03 7.2e-04 1.0e-03
9 PL gene expression Il18bp 0.03 0.03 4.6e-03 0.02 0.02 0.02 0.02 1.2e-03 3.7e-03 2.2e-03 3.1e-03
10 Brain mRNA stability Il18bp 0.04 0.03 7.9e-04 0.01 0.03 0.01 0.02 1.4e-02 2.0e-03 1.4e-02 9.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.10.10.4-0.60.50.4-0.1-0.3-0.20.30.3-0.2-0.0
Area under the delay curve0.20.21.0-0.80.4-0.20.30.30.2-0.4-0.20.2-1.0
BMI with tail1.75.68.5-0.91.82.5-2.6-2.9-2.52.52.5-2.42.3
BMI without tail0.10.31.21.1-0.9-0.3-0.1-0.00.1-0.3-0.20.30.7
Body weight0.31.31.61.1-1.2-1.21.31.01.2-1.2-1.21.3-0.6
Weight adjusted by age0.80.92.51.6-1.2-0.90.80.90.9-0.8-0.91.00.1
Bone surface0.71.22.10.9-1.2-1.21.51.11.1-1.1-1.11.1-0.5
Bone volume0.50.91.70.6-0.9-1.01.31.01.0-0.9-1.01.0-0.5
Breakpoint value in progressive ratio session1.21.32.4-1.00.71.0-1.1-1.0-1.51.21.5-1.30.9
Number of licking bursts1.41.75.5-2.42.11.2-0.9-0.8-0.90.80.9-0.9-0.8
Context. condit. distance diff. score0.81.04.22.1-1.7-0.70.50.40.1-0.1-0.10.21.4
Locomotion velocity, session 12.32.53.3-0.91.31.6-1.7-1.7-1.81.71.7-1.81.3
Locomotion distance, session 10.91.12.70.5-0.00.8-1.1-1.0-1.21.01.2-1.21.7
Locomotion velocity, session 21.11.32.1-0.10.51.0-1.1-1.1-1.51.21.3-1.41.4
Locomotion distance, session 21.01.42.90.30.31.1-1.1-1.2-1.41.21.3-1.41.7
Locomotion velocity, session 30.20.20.70.8-0.8-0.50.50.40.1-0.3-0.10.00.4
Locomotion distance, session 30.20.20.80.9-0.8-0.20.10.1-0.20.10.3-0.20.8
Stereotopy head waving bouts, day 30.50.61.00.1-0.3-0.70.70.80.9-0.9-1.00.9-1.0
Stereotopy head waving duration, day 30.10.10.30.5-0.20.1-0.3-0.3-0.10.0-0.0-0.10.5
Locomotion velocity, session 70.91.01.6-0.40.71.0-0.7-1.0-1.21.11.3-1.21.0
Locomotion distance, session 70.10.10.2-0.50.40.10.40.0-0.10.10.2-0.1-0.3
Stereotopy head waving bouts, day 70.91.03.92.0-1.8-0.90.50.60.5-0.7-0.50.50.9
Stereotopy head waving duration, day 70.81.04.22.0-1.7-0.80.30.40.3-0.5-0.40.41.1
Locomotion velocity, session 80.50.61.81.4-1.3-0.80.90.70.3-0.3-0.40.30.5
Locomotion distance, session 80.71.03.71.9-1.4-0.2-0.2-0.1-0.40.30.4-0.41.9
Degree of sensitization distance0.70.71.5-0.3-0.1-0.71.00.90.9-0.8-0.90.8-1.2
Degree of sensitization stereotypy1.82.07.22.7-2.4-1.30.80.90.6-0.7-0.60.71.2
Conditioned locomotion0.40.41.3-0.60.1-0.50.80.80.5-0.5-0.50.5-1.2
Cocaine response after cond. corrected0.40.51.5-1.21.20.7-0.5-0.6-0.40.50.4-0.4-0.4
Cocaine response after cond. not corrected0.90.91.3-0.91.11.1-0.9-1.1-0.91.10.9-0.90.5
Cocaine response before conditioning0.81.03.51.0-0.50.6-0.8-0.9-0.90.90.9-0.91.9
Saline control response3.54.55.91.9-2.4-2.42.22.22.2-2.2-2.22.2-1.0
Bone: connectivity density1.11.72.2-0.70.91.3-1.3-1.4-1.41.51.5-1.51.2
Bone: cortical apparent density0.30.41.6-1.20.8-0.00.30.20.3-0.4-0.30.3-1.3
Bone: cortical area0.50.71.50.6-0.9-1.01.21.00.8-0.8-0.80.8-0.5
Bone: cortical porosity0.20.30.40.3-0.5-0.60.50.60.6-0.5-0.40.6-0.4
Bone: cortical porosity0.30.30.50.4-0.5-0.60.70.70.7-0.6-0.60.7-0.4
Bone: cortical thickness0.40.71.0-0.70.80.9-0.7-0.9-0.90.91.0-0.90.5
Bone: cortical thickness0.00.00.00.1-0.1-0.10.00.10.00.0-0.00.0-0.0
Bone: cortical tissue density0.30.41.5-1.20.80.00.20.20.3-0.4-0.30.2-1.2
Condit. Reinf. active minus inactive responses2.12.43.11.1-1.4-1.61.41.61.8-1.7-1.71.8-1.1
Condit. Reinf. active-inactive response ratio4.04.45.81.3-1.8-2.21.92.22.4-2.4-2.32.4-1.6
Condit. Reinf. active responses1.11.42.00.4-0.7-1.21.21.21.4-1.3-1.41.4-1.3
Condit. Reinf. inactive responses0.20.30.6-0.70.80.6-0.2-0.5-0.40.50.4-0.5-0.0
Incentive salience index mean1.31.62.20.7-0.9-1.31.11.21.5-1.5-1.41.5-1.1
Condit. Reinf. lever presses0.00.00.1-0.10.1-0.0-0.00.00.2-0.2-0.20.2-0.2
Condit. Reinf. active minus inactive responses5.06.212.53.3-3.5-2.72.52.42.2-2.2-2.22.20.1
Condit. Reinf. active-inactive response ratio0.60.61.81.3-1.3-0.70.70.50.5-0.4-0.50.50.6
Condit. Reinf. active responses7.09.718.03.9-4.2-3.43.13.02.9-2.9-2.92.9-0.2
Condit. Reinf. inactive responses4.75.89.22.7-3.0-2.62.32.42.4-2.4-2.42.4-0.6
Condit. Reinf. lever presses6.38.623.74.9-4.6-2.92.42.32.2-2.2-2.22.21.4
Condit. Reinf. lever reinforcers received6.99.818.84.1-4.3-3.43.03.02.9-2.9-2.92.8-0.0
Conditioned reinforcement - actives0.10.10.30.2-0.30.1-0.1-0.2-0.60.30.5-0.40.5
Conditioned reinforcement - inactives0.40.51.4-0.50.2-0.40.70.60.7-0.5-0.70.8-1.2
Conditioned locomotion0.60.72.31.0-0.50.4-0.7-0.6-0.80.70.7-0.81.5
Patch foraging indifference point 0 sec0.71.24.72.2-1.7-0.90.50.50.8-0.9-0.80.60.9
Patch foraging indifference point AUC0.60.71.10.9-0.8-0.90.80.80.9-1.0-0.90.7-0.4
Delay disc. indifference point, 0s delay0.20.20.60.7-0.6-0.40.30.30.3-0.3-0.30.20.2
Delay disc. indifference point, 16s delay0.70.82.4-0.60.1-0.70.90.90.8-0.9-0.80.8-1.5
Delay disc. indifference point, 2s delay0.91.01.50.6-1.0-1.21.11.11.0-1.2-1.01.0-0.8
Delay disc. indifference point, 24s delay0.50.41.7-1.30.90.00.20.20.2-0.3-0.20.2-1.3
Delay disc. indifference point, 4s delay1.11.11.50.8-1.1-1.21.11.11.1-1.2-1.11.0-0.7
Delay disc. indifference point, 8s delay0.20.20.8-0.90.50.2-0.0-0.0-0.4-0.00.4-0.4-0.4
Indifference point function ln k0.10.10.50.1-0.00.3-0.2-0.4-0.40.50.4-0.20.7
Indifference point function log k0.10.10.50.1-0.00.3-0.2-0.4-0.40.50.4-0.20.7
Patch foraging total patch changes 0 sec0.50.93.92.0-1.4-0.60.30.30.5-0.6-0.60.31.0
Patch foraging total patch changes 12 sec1.21.52.11.5-1.4-1.31.01.31.3-1.4-1.31.0-0.4
Patch foraging total patch changes 18 sec0.50.71.71.3-1.2-0.80.70.60.7-0.9-0.70.50.2
Patch foraging total patch changes 24 sec1.41.72.91.7-1.5-1.31.31.21.4-1.3-1.41.2-0.3
Patch foraging total patch changes 6 sec0.40.63.01.7-0.9-0.40.00.00.7-0.7-0.80.50.6
Patch foraging time to switch 0 sec1.31.97.3-2.72.21.2-0.9-0.8-0.90.90.9-1.0-1.0
Patch foraging water rate 0 sec0.91.55.92.4-1.9-1.10.80.70.7-0.9-0.70.80.8
Patch foraging water rate 12 sec1.21.96.71.5-0.60.9-1.2-1.2-1.11.31.2-1.12.6
Patch foraging water rate 18 sec0.70.94.12.0-1.6-0.40.20.2-0.00.00.1-0.01.6
Patch foraging water rate 24 sec0.71.02.40.40.20.9-0.9-1.1-1.01.01.1-1.01.6
Patch foraging water rate 6 sec0.50.82.70.9-0.30.6-0.5-0.9-0.80.90.9-0.81.7
Seeking ratio, delayed vs. immediate footshock1.51.73.1-1.61.81.5-1.1-1.2-1.31.51.3-1.10.2
Distance traveled before self-admin0.80.91.3-0.81.11.1-1.1-0.9-1.01.10.9-0.80.4
Distance traveled after self-admin0.60.71.20.20.10.6-0.8-0.7-1.01.01.0-0.91.1
Extensor digitorum longus weight0.10.20.4-0.60.60.5-0.2-0.3-0.50.50.4-0.50.0
Bone: elastic displacement2.62.94.2-1.61.91.9-2.0-1.8-1.71.71.7-1.70.7
Bone: elastic work5.16.68.9-2.02.62.8-3.0-2.7-2.62.72.7-2.61.5
Bone: endosteal estimation1.94.06.21.5-2.1-2.22.52.32.0-1.9-2.02.0-1.2
Bone: endosteal perimeter1.83.85.51.9-2.3-2.22.42.11.9-1.8-1.91.9-0.8
Epididymis fat weight0.10.10.7-0.80.50.1-0.1-0.2-0.10.00.1-0.1-0.5
Delta time in closed arm before/after self-admin0.70.62.1-0.70.2-0.50.70.70.7-0.9-0.80.7-1.4
Delta time in open arm before/after self-admin2.52.43.71.9-1.8-1.61.51.51.7-1.1-1.81.7-0.3
Diff in mean of infusions in LGA sessions1.11.24.1-1.20.5-0.60.80.91.0-0.9-1.01.2-2.0
Delay discount exponential model param0.20.21.01.0-0.6-0.0-0.1-0.10.00.2-0.00.00.9
Extinction: sum of active levers before priming0.10.10.4-0.70.40.4-0.2-0.3-0.40.40.4-0.40.0
Active lever presses in extinction session 60.60.62.41.2-0.50.4-0.7-0.6-0.40.70.4-0.31.5
Bone: final force1.22.03.7-0.4-0.4-1.31.81.51.5-1.5-1.51.5-1.9
Bone: final moment1.11.82.9-0.2-0.5-1.31.71.51.4-1.4-1.51.4-1.7
Food consumed during 24 hour testing period0.60.73.11.8-1.4-0.50.10.30.2-0.3-0.20.21.2
Glucose0.60.91.4-0.20.40.9-1.0-0.9-1.21.11.2-1.11.1
Heart weight0.60.82.71.7-1.2-0.70.60.50.9-0.4-0.90.90.3
Delay discount hyperbolic model param0.20.20.80.8-0.30.2-0.3-0.3-0.20.40.2-0.10.9
Intermittent access intake day 1-15 change1.51.53.70.80.21.1-1.4-1.5-1.11.31.1-1.01.9
Intermittent access intake escalation1.71.73.70.60.31.2-1.5-1.6-1.21.51.2-1.21.9
Intermittent access intake escalation 20.70.71.0-0.30.60.9-0.9-1.0-0.81.00.8-0.80.8
Intermitt. access day 1 inactive lever presses0.60.62.2-1.10.8-0.10.50.40.7-0.5-0.60.7-1.5
Intermitt. access day 15 inactive lever presses0.20.21.01.0-0.4-0.20.1-0.10.6-0.0-0.50.80.2
Intermitt. access escalation Index0.30.30.50.1-0.3-0.50.50.30.6-0.7-0.60.7-0.5
Intermittent access day 1 total infusions0.91.11.90.8-1.4-1.41.41.30.6-1.1-0.70.7-0.6
Intermittent access day 15 total infusions0.10.20.60.8-0.7-0.30.30.1-0.1-0.00.1-0.00.4
Intermittent access terminal intake (last 3 days)0.20.20.70.6-0.9-0.60.50.4-0.1-0.30.10.00.1
Intermittent access total infusions0.20.30.70.3-0.9-0.70.80.60.0-0.5-0.10.1-0.2
Intermittent access day 1 locomotion0.20.20.4-0.0-0.2-0.50.60.60.4-0.5-0.40.5-0.7
Intermittent access day 15 total locomotion0.30.41.20.8-0.20.4-0.5-0.6-0.40.60.5-0.51.1
Intermittent access total locomotion0.10.10.40.7-0.6-0.30.30.20.0-0.0-0.00.00.3
Intermittent access standard deviation0.70.71.1-0.40.70.9-1.0-1.0-0.91.00.8-0.90.8
Left kidney weight0.51.33.92.0-1.6-1.01.00.71.1-0.7-1.01.10.4
Right kidney weight0.51.32.51.6-1.2-1.01.10.81.3-0.8-1.31.3-0.1
Cocaine induced anxiety0.80.93.7-1.91.50.40.00.00.3-0.0-0.30.3-1.5
Post-drug Anxiety1.61.83.7-0.2-0.3-1.21.41.41.5-1.5-1.51.5-1.9
Baseline Anxiety2.12.33.91.8-2.0-1.71.51.51.3-1.6-1.31.4-0.4
Tail length7.522.828.54.1-5.1-5.34.95.14.9-5.2-4.95.0-2.7
Length with tail4.416.219.43.0-3.9-4.44.24.44.3-4.2-4.34.4-2.8
Length without tail0.00.10.3-0.40.40.00.30.20.30.2-0.10.2-0.6
Times rat made contact with spout0.20.20.5-0.50.2-0.20.50.30.3-0.4-0.30.4-0.7
Lifetime Intake0.30.31.10.7-1.0-0.70.60.5-0.0-0.40.00.00.2
Liver weight, left1.52.57.9-1.50.2-1.31.61.91.3-1.3-1.31.3-2.8
Liver weight, right3.04.911.3-0.9-0.4-2.02.62.52.2-2.3-2.22.2-3.4
Locomotor activity0.10.20.70.8-0.5-0.00.1-0.0-0.20.20.2-0.10.8
Locomotor testing distance0.40.72.91.7-1.5-0.60.70.40.1-0.2-0.10.21.1
Locomotor testing rearing0.61.02.00.9-1.4-1.21.41.10.7-0.9-0.70.7-0.2
Locomotion in novel chamber1.92.33.5-0.71.31.7-1.7-1.9-1.51.61.5-1.51.4
Locomotion in novel chamber post-restriction0.30.31.30.5-0.40.3-0.4-0.6-0.50.50.5-0.51.1
Fecal boli incidents, locomotor time 10.50.62.8-1.71.10.4-0.4-0.1-0.50.20.5-0.5-0.8
Change in fecal boli incidents, locomotor task0.10.10.30.3-0.3-0.20.50.20.2-0.2-0.30.10.0
Time >=10cm from walls, locomotor time 10.60.60.90.9-0.9-0.80.90.70.7-0.9-0.80.7-0.2
Bouts of movement, locomotor time 10.91.02.20.6-0.5-0.90.81.01.4-0.8-1.21.5-0.9
Total resting periods, locomotor time 10.20.20.6-0.00.1-0.20.20.30.7-0.2-0.50.8-0.6
Rest time, locomotor task time 10.30.30.70.0-0.5-0.70.70.80.4-0.7-0.40.5-0.7
Distance moved, locomotor task time 10.00.00.10.00.10.2-0.2-0.3-0.20.20.2-0.20.3
Vertical activity count, locomotor time 10.00.00.1-0.10.0-0.10.40.30.1-0.2-0.20.2-0.3
Time >=10cm from walls, locomotor time 23.63.85.22.0-2.2-2.22.32.01.9-1.9-2.01.9-0.9
Bouts of movement, locomotor time 23.03.24.70.0-1.1-1.92.02.21.8-1.9-1.82.0-2.2
Total resting periods, locomotor time 21.92.14.1-0.5-0.6-1.51.51.81.4-1.5-1.41.5-2.0
Rest time, locomotor task time 21.61.94.4-2.11.81.3-1.1-1.0-1.41.11.4-1.3-0.2
Distance moved, locomotor task time 21.41.64.12.0-1.8-1.31.21.01.1-1.1-1.01.00.3
Vertical activity count, locomotor time 21.21.32.10.6-1.1-1.31.41.41.0-1.3-1.11.0-1.0
Light reinforcement 12.44.46.4-2.22.52.4-2.0-2.1-2.12.12.1-2.20.8
Light reinforcement 24.76.38.4-0.71.52.5-2.8-2.6-2.92.62.8-2.92.6
Bone: marrow area1.73.75.91.3-1.9-2.12.42.21.9-1.9-2.01.9-1.3
Bone: maximum diameter1.93.55.32.0-2.3-2.12.21.91.8-1.7-1.81.8-0.6
Bone: maximum force0.81.32.6-0.2-0.5-1.11.61.31.2-1.1-1.11.2-1.4
Bone: maximum moment0.50.91.90.0-0.6-1.01.41.11.0-0.9-1.00.9-1.1
Mean time between licks in bursts7.911.013.53.1-3.7-3.63.43.43.5-3.4-3.53.6-1.5
Mean num. licks in bursts1.41.64.52.1-2.0-1.31.00.91.0-1.0-1.01.00.6
Cd content in liver0.20.21.0-1.00.60.2-0.20.0-0.40.20.4-0.4-0.5
Co content in liver4.65.46.61.8-2.3-2.62.52.52.5-2.4-2.52.4-1.6
Cu content in liver2.32.83.51.2-1.6-1.91.81.81.8-1.8-1.81.8-1.2
Fe content in liver0.70.81.4-0.0-0.3-0.91.01.01.0-1.0-1.01.0-1.2
K content in liver0.20.20.6-0.80.80.4-0.3-0.3-0.10.20.1-0.1-0.4
Mg content in liver0.00.00.10.10.10.2-0.3-0.3-0.10.20.1-0.10.3
Mn content in liver2.42.83.9-1.92.01.8-1.5-1.6-1.71.71.7-1.70.5
Na content in liver0.00.00.20.5-0.3-0.10.10.00.10.1-0.10.10.3
Rb content in liver0.70.91.10.9-1.0-1.11.01.00.9-1.1-0.90.9-0.5
Se content in liver1.72.07.2-2.72.21.3-0.9-0.9-1.01.01.0-0.9-0.8
Sr content in liver2.01.93.70.10.51.3-1.5-1.5-1.41.51.4-1.41.9
Zn content in liver0.60.72.91.7-1.2-0.2-0.2-0.2-0.30.10.3-0.21.6
Bone: minimum diameter1.83.35.40.9-1.6-2.02.32.11.8-1.8-1.81.9-1.5
Time in familiar zone, hab. session 10.10.10.30.5-0.5-0.30.10.3-0.0-0.1-0.1-0.10.2
Time in novel zone, hab. session 10.20.20.7-0.50.2-0.20.50.30.5-0.5-0.40.6-0.8
Total zone transitions, hab. session 10.30.40.90.3-0.00.4-0.7-0.6-0.60.60.6-0.60.9
Total locomotion distance, hab. session 10.71.01.50.1-0.4-0.90.91.01.1-1.2-1.21.1-1.2
Locomotion velocity, hab. session 10.30.50.9-0.1-0.2-0.60.50.70.8-0.9-0.90.8-1.0
Time in familiar zone, hab. session 23.03.14.52.0-2.1-1.91.81.81.7-1.8-1.81.7-0.5
Time in novel zone, hab. session 23.73.74.6-1.41.82.1-2.1-2.1-2.02.12.1-2.01.3
Total zone transitions, hab. session 20.70.94.72.2-1.3-0.3-0.2-0.10.10.1-0.20.11.5
Total locomotion distance, hab. session 21.21.52.21.3-1.2-1.31.11.21.4-1.3-1.51.3-0.6
Locomotion velocity, hab. session 21.21.62.31.1-1.2-1.31.21.31.4-1.3-1.51.4-0.8
Novel to familiar place preference ratio2.92.94.50.4-1.0-1.71.71.72.1-1.9-1.92.1-1.8
Novelty place preference2.62.74.00.4-1.0-1.61.71.62.0-1.8-1.82.0-1.7
Time in novel zone, NPP test3.03.14.60.6-1.2-1.81.81.82.1-2.0-2.02.1-1.7
Total zone transitions, NPP test1.42.03.30.10.61.4-1.7-1.6-1.61.61.5-1.51.8
Total locomotion distance, NPP test0.20.30.7-0.30.60.7-0.8-0.7-0.60.50.5-0.50.4
Locomotion velocity, NPP test0.50.71.2-0.71.01.0-1.1-1.0-0.90.80.8-0.80.5
Intraocular pressure0.30.40.8-0.00.40.8-0.8-0.9-0.50.70.6-0.50.8
Delta distance traveled before/after self-admin2.02.24.21.5-2.0-1.81.71.61.2-1.5-1.21.2-0.4
Delta ambulatory time before/after self-admin1.11.22.81.3-1.7-1.31.21.10.7-1.1-0.80.7-0.0
Parametrial fat weight1.22.33.1-1.21.51.6-1.5-1.5-1.71.81.7-1.50.9
Pavlov. Cond. lever latency0.81.01.2-0.91.11.1-0.9-1.0-1.01.11.0-1.00.4
Pavlov. Cond. magazine entry latency1.31.64.32.1-2.0-1.31.01.10.9-1.0-0.90.90.5
Pavlov. Cond. change in total contacts2.22.32.91.2-1.6-1.71.71.71.6-1.6-1.61.6-0.8
Pavlov. Cond. index score1.21.53.31.7-1.8-1.31.11.21.0-1.1-1.01.00.1
Pavlov. Cond. latency score1.31.63.11.6-1.8-1.41.21.31.1-1.2-1.11.1-0.1
Pavlov. Cond. lever contacts0.60.71.00.9-1.0-0.90.80.90.8-0.8-0.80.8-0.2
Pavlov. Cond. magazine entry number1.11.33.7-1.91.91.2-0.8-1.0-0.80.90.9-0.8-0.5
Pavlov. Cond. intertrial magazine entries0.20.21.1-1.00.90.30.1-0.1-0.10.10.1-0.1-0.7
Pavlov. Cond. lever-magazine prob. diff.0.91.22.61.5-1.6-1.20.91.10.9-1.0-0.90.90.1
Pavlov. Cond. response bias0.50.61.41.1-1.2-0.90.60.80.7-0.7-0.70.70.1
Pavlov. Cond. lever latency5.67.626.6-5.24.62.5-2.0-1.7-1.61.61.6-1.6-2.1
Pavlov. Cond. magazine entry latency1.82.07.92.1-1.10.5-1.0-1.1-1.11.01.1-1.12.8
Pavlov. Cond. change in total contacts4.66.323.94.9-4.2-2.11.41.31.3-1.4-1.31.32.4
Pavlov. Cond. index score3.54.518.84.3-3.6-1.61.00.90.8-0.8-0.80.82.4
Pavlov. Cond. latency score2.93.616.04.0-3.2-1.20.70.50.4-0.4-0.40.42.6
Pavlov. Cond. lever contacts6.28.428.45.3-4.7-2.72.11.91.9-1.9-1.91.92.0
Pavlov. Cond. magazine entry number1.82.29.2-3.02.20.30.30.30.3-0.3-0.30.4-2.7
Pavlov. Cond. intertrial magazine entries1.92.53.30.5-1.0-1.61.61.71.8-1.8-1.81.8-1.6
Pavlov. Cond. lever-magazine prob. diff.3.54.418.44.3-3.6-1.71.10.90.9-0.9-0.90.82.3
Pavlov. Cond. response bias5.57.528.45.3-4.6-2.31.61.51.5-1.5-1.51.42.5
Time in closed arm before self-admin0.70.72.91.5-1.00.1-0.5-0.4-0.50.40.5-0.41.7
Time in closed arm after self-admin0.10.10.4-0.70.60.3-0.3-0.2-0.20.10.2-0.2-0.3
Time in open arm before self-admin2.52.77.0-2.72.61.8-1.5-1.4-1.21.11.2-1.1-0.6
Time in open arm after self-admin0.40.40.80.2-0.2-0.50.60.60.8-0.5-0.90.9-0.7
Bone: periosteal estimation1.22.44.31.1-1.7-1.82.11.81.5-1.4-1.51.5-0.9
Bone: periosteal perimeter1.01.62.71.4-1.7-1.51.61.31.2-1.1-1.11.2-0.3
Bone: post-yield work0.10.10.70.3-0.5-0.40.80.40.1-0.1-0.00.10.1
Progressive ratio test 1 active lever presses0.00.00.10.0-0.2-0.10.20.1-0.20.00.2-0.1-0.0
Progressive ratio test 1 breakpoint0.00.00.10.0-0.3-0.30.30.3-0.1-0.10.10.0-0.2
Progressive ratio test 1 inactive lever presses0.00.00.20.1-0.1-0.20.40.20.00.00.00.1-0.2
Progressive ratio test 2 active lever presses0.40.41.10.2-0.7-0.91.00.80.3-0.7-0.30.4-0.6
Progressive ratio test 2 breakpoint0.50.61.30.3-0.8-1.01.10.90.5-0.8-0.50.5-0.7
Progressive ratio test 2 inactive lever presses0.00.00.10.2-0.3-0.20.40.1-0.20.10.2-0.0-0.0
Incentive Sensitization - Responses0.90.91.50.6-1.1-1.21.21.10.7-1.1-0.70.7-0.6
Incentive Sensitization - Breakpoint0.40.40.80.4-0.9-0.90.90.80.4-0.8-0.40.4-0.3
Sum of active levers in priming session hrs 5-60.20.20.50.1-0.00.3-0.4-0.4-0.60.40.6-0.40.7
Progressive ratio0.40.51.00.30.40.8-0.9-0.9-0.51.00.5-0.60.9
Food seeking constrained by brief footshock1.72.13.11.8-1.7-1.51.21.11.6-1.3-1.61.7-0.2
Seeking ratio, punishment vs. effort1.41.72.70.7-1.5-1.51.51.41.2-1.7-1.21.3-0.8
Retroperitoneal fat weight0.20.83.3-1.81.10.00.40.30.1-0.2-0.20.3-1.7
Reaction time number correct0.20.30.5-0.10.30.6-0.7-0.6-0.70.50.7-0.60.7
Reaction time mean minus median0.30.40.60.8-0.8-0.70.60.70.5-0.5-0.50.4-0.2
Reaction time mean minus median AUC0.20.20.50.7-0.7-0.50.60.50.2-0.4-0.20.1-0.0
Reaction time num false alarms0.60.83.1-1.81.30.20.30.10.4-0.3-0.40.3-1.6
Reaction time num false alarms AUC0.50.73.3-1.81.30.40.1-0.10.0-0.1-0.1-0.1-1.4
Reaction time trials correct on left0.20.30.5-0.10.30.6-0.7-0.6-0.70.50.7-0.60.7
Reaction time trials on left0.30.40.7-0.20.40.7-0.8-0.7-0.80.60.8-0.70.7
Reaction time mean0.50.73.1-1.50.8-0.30.60.70.3-0.4-0.40.3-1.8
Reaction time mean AUC0.60.83.1-1.70.9-0.20.50.60.3-0.3-0.30.2-1.8
Median of all reaction times0.70.94.3-2.11.20.10.30.40.0-0.1-0.10.0-1.8
Reaction time omissions0.60.81.7-1.31.10.8-0.7-0.7-1.00.71.0-1.0-0.1
Reaction time false alarm rate0.50.73.0-1.71.30.30.2-0.00.1-0.0-0.1-0.0-1.4
Reaction time premature initiation rate1.41.93.31.6-1.8-1.61.41.51.2-1.4-1.21.2-0.4
Reaction time premature initiations0.40.61.51.2-1.2-0.90.50.70.5-0.7-0.50.40.2
Std. dev. reaction times1.01.42.6-0.1-0.6-1.21.41.51.1-1.2-1.11.0-1.6
Reaction time trials completed0.30.40.7-0.20.40.7-0.8-0.7-0.80.60.8-0.70.7
Reaction time trials AUC0.20.20.4-0.10.20.5-0.6-0.5-0.60.30.6-0.50.5
Run reversals in cocaine runway, females0.20.20.40.6-0.7-0.60.50.50.4-0.5-0.30.4-0.1
Run reversals in cocaine runway, males0.10.10.4-0.50.60.3-0.2-0.3-0.10.40.1-0.1-0.4
Latency to leave start box in cocaine runway0.40.42.3-1.50.80.3-0.10.0-0.50.00.5-0.6-0.8
Latency to leave start box in cocaine runway, F0.40.41.6-1.10.4-0.30.60.60.3-0.7-0.30.2-1.3
Latency to leave start box in cocaine runway, M1.01.01.7-1.31.00.9-0.9-0.8-1.20.81.2-1.20.3
Std. dev. time between licks in bursts3.13.74.71.2-1.8-2.12.02.22.1-2.0-2.12.1-1.4
Total sessions with >9 infusions0.80.92.91.3-1.2-0.1-0.2-0.3-1.00.41.0-0.91.7
Short access day 1 total inactive lever presses0.50.51.6-0.50.3-0.40.70.70.8-0.5-0.70.9-1.3
Short access day 10 total inactive lever presses0.30.31.1-0.91.00.6-0.4-0.4-0.20.30.2-0.1-0.4
Short access day 1 total infusions0.70.82.41.1-1.6-1.21.01.00.3-0.8-0.30.40.0
Short access day 10 total infusions0.50.61.71.0-1.3-1.00.90.80.2-0.7-0.20.20.0
Short access total infusions0.40.51.61.1-1.3-0.90.70.60.1-0.4-0.10.20.2
Short access day 1 locomotion0.90.91.90.4-0.00.7-0.8-0.8-1.31.11.2-1.11.4
Short access day 10 total locomotion0.30.40.6-0.30.30.6-0.7-0.7-0.70.50.7-0.80.7
Short access total locomotion0.20.20.5-0.20.20.4-0.4-0.3-0.70.50.7-0.70.5
One hour access (0.3 mA shock)0.20.30.80.7-0.50.0-0.1-0.2-0.60.40.6-0.70.9
Compulsive drug intake0.40.40.9-0.40.90.9-0.8-0.7-0.50.80.5-0.50.4
One hour access (shock baseline)0.30.41.20.8-1.1-0.80.70.50.2-0.5-0.20.10.1
Social response proportion0.10.20.4-0.20.60.3-0.6-0.50.30.0-0.30.4-0.2
Social responses0.40.51.2-0.40.1-0.50.60.50.8-0.8-0.80.9-1.1
Social time1.31.84.6-2.11.71.3-1.4-1.0-1.21.01.2-1.2-0.2
Soleus weight0.30.81.8-0.3-0.1-0.71.00.81.0-0.9-1.01.0-1.3
Bone: stiffness2.74.27.5-0.4-0.6-1.82.42.22.2-2.2-2.32.2-2.7
Tibialis anterior weight0.20.82.20.4-0.7-0.91.51.00.9-0.9-0.90.9-0.8
Time to tail flick, vehicle, before self-admin0.10.10.70.8-0.4-0.20.30.00.0-0.00.10.30.3
Time to tail flick, vehicle, after self-admin0.60.61.81.1-1.4-0.90.60.80.6-0.6-0.40.70.3
Time to tail flick, test, before self-admin2.22.23.61.9-1.6-1.51.41.31.6-1.4-1.61.6-0.4
Time to tail flick, test, after self-admin4.74.86.62.0-2.0-2.22.12.12.6-2.3-2.52.5-1.3
Delta time to tail flick, vehicle, before/after SA0.00.00.20.1-0.4-0.1-0.10.1-0.0-0.10.0-0.00.4
Delta time to tail flick, test, before/after SA0.10.10.1-0.30.40.3-0.3-0.2-0.00.20.1-0.0-0.1
Tibia length0.30.81.61.2-1.3-0.90.80.80.7-0.7-0.80.70.1
Ambulatory time before self-admin0.91.01.4-1.11.21.0-1.1-0.8-1.01.11.0-0.90.3
Ambulatory time after self-admin0.20.20.50.2-0.40.1-0.2-0.1-0.60.50.6-0.40.7
Bone: tissue strength3.23.13.9-0.71.31.9-1.9-2.0-1.91.92.0-1.91.7
Total heroin consumption0.20.21.00.7-0.60.1-0.2-0.2-0.40.30.4-0.21.0
Bone: trabecular number1.11.72.6-1.61.51.4-1.2-1.3-1.31.31.3-1.20.4
Bone: trabecular spacing0.70.92.30.8-0.10.7-1.2-0.9-0.90.80.9-0.91.5
Bone: trabecular thickness2.12.63.8-0.1-0.7-1.51.91.81.8-1.7-1.71.8-2.0
Bone: trabecular tissue density3.65.111.0-0.6-0.5-2.02.42.42.3-2.5-2.42.3-3.3
Water consumed over 24 hours0.30.30.8-0.90.90.6-0.6-0.5-0.40.40.4-0.4-0.2
Number of responses in last shaping day0.90.92.0-0.2-0.6-1.11.41.20.7-1.0-0.70.7-1.3