Ift20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose alternative TSS NM_001105815.1 0.12 0.09 3.0e-12 0.09 0.09 0.1 0.1 2.5e-10 2.5e-10 1.2e-10 2.1e-11
2 PL isoform ratio XM_063268683.1 0.06 0.05 1.1e-07 0.09 0.06 0.09 0.09 6.1e-10 5.2e-07 3.5e-10 1.7e-10
3 PL intron excision ratio chr10_63930861_63932596 0.03 0.03 1.8e-04 0.02 0.03 0.02 0.02 2.3e-03 7.0e-04 3.7e-03 2.5e-03
4 NAcc intron excision ratio chr10_63930861_63932596 0.03 0.03 5.3e-05 0.02 0.03 0.02 0.02 3.3e-04 4.6e-05 3.5e-04 3.0e-04
5 NAcc intron excision ratio chr10_63933081_63934663 0.01 0.01 9.3e-03 0.01 0.01 -0 0.01 2.0e-02 8.5e-03 4.2e-01 2.2e-02
6 NAcc gene expression Ift20 0.02 0.02 6.5e-04 0.02 0.02 0.02 0.02 4.9e-04 3.6e-04 4.9e-04 5.1e-04
7 Adipose alternative TSS NM_001105815.1 0.04 0.04 4.2e-05 0.02 0.03 0.02 0.02 1.3e-03 2.9e-04 1.4e-03 1.5e-03
8 Eye intron excision ratio chr10_63933081_63934663 0.24 0.21 9.9e-03 0.07 0.12 0.07 0.1 3.3e-02 7.3e-03 3.2e-02 1.1e-02
9 NAcc isoform ratio XM_063268683.1 0.02 0.02 2.0e-04 0.01 0.01 0.01 0.01 4.1e-03 1.9e-03 5.8e-03 8.0e-03
10 pVTA gene expression Ift20 0.06 0.04 1.8e-05 0.04 0.06 0.05 0.05 1.6e-04 2.7e-05 8.9e-05 4.9e-05
11 Liver mRNA stability Ift20 0.02 0.02 7.4e-03 0.01 0.01 0.01 0.01 6.6e-02 2.4e-02 3.6e-02 4.0e-02
12 Adipose gene expression Ift20 0.13 0.09 8.9e-16 0.1 0.12 0.11 0.11 1.6e-11 2.0e-13 1.5e-12 1.6e-12
13 Adipose isoform ratio XM_006246935.5 0.17 0.22 1.4e-09 0.06 0.07 0.07 0.07 1.3e-07 2.6e-08 6.9e-08 8.5e-08
14 Adipose alternative TSS XM_063268683.1 0.19 0.15 5.6e-17 0.12 0.13 0.13 0.13 9.8e-14 1.9e-14 7.0e-14 6.1e-14
15 BLA intron excision ratio chr10_63930861_63932596 0.15 0.15 6.1e-04 0.04 0.04 0.04 0.04 2.2e-03 2.7e-03 5.2e-03 3.0e-03
16 Adipose alternative TSS XM_063268683.1 0.06 0.05 2.7e-06 0.04 0.04 0.04 0.04 1.1e-05 3.1e-05 4.2e-05 2.6e-05
17 Adipose isoform ratio NM_001105815.1 0.12 0.14 6.5e-09 0.08 0.07 0.07 0.07 7.6e-09 7.7e-08 2.3e-08 7.7e-08
18 PL isoform ratio NM_001105815.1 0.03 0.03 8.4e-04 0.05 0.02 0.04 0.04 6.6e-06 1.5e-03 8.0e-05 1.0e-04
19 IC gene expression Ift20 0.07 0.07 7.0e-03 0.03 0.03 0.02 0.03 2.2e-02 2.2e-02 6.8e-02 1.8e-02
20 Liver isoform ratio NM_001105815.1 0.06 0.1 2.7e-03 0.02 0.01 0.01 0.02 2.3e-03 9.8e-03 7.7e-03 6.2e-03
21 Liver isoform ratio XM_006246935.5 0.13 0.17 6.6e-03 0.01 0 -0 0 6.0e-02 9.7e-02 5.0e-01 1.1e-01
22 PL intron excision ratio chr10_63933081_63934663 0.02 0.02 4.2e-03 0.02 0.02 0.02 0.02 1.3e-03 5.5e-03 3.8e-03 5.1e-03
23 Adipose intron excision ratio chr10_63933081_63934663 0.28 0.19 4.1e-06 0.03 0.04 0.03 0.03 5.4e-04 3.3e-05 1.8e-04 2.3e-04
24 Adipose intron excision ratio chr10_63930861_63932596 0.09 0.07 3.2e-08 0.05 0.05 0.05 0.05 6.8e-06 1.9e-06 1.7e-06 3.0e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density2.13.75.1-2.0-2.01.91.9-1.91.9-1.9-1.9-2.02.0-2.01.9-2.02.01.92.31.81.92.02.0-1.9-2.0-1.61.3
Area under the delay curve1.31.53.30.80.5-1.2-1.01.1-1.11.21.21.3-1.31.3-1.21.3-1.3-0.3-1.8-0.8-0.2-1.7-1.71.61.80.3-1.2
BMI with tail1.96.68.6-2.9-2.82.62.6-2.62.6-2.6-2.6-2.62.6-2.62.6-2.62.62.72.62.82.52.42.4-2.5-2.3-2.42.1
BMI without tail2.06.07.4-2.7-2.52.52.4-2.42.4-2.5-2.5-2.52.5-2.52.5-2.52.52.52.72.32.32.62.6-2.4-2.3-1.81.9
Body weight2.711.914.1-3.8-3.63.53.6-3.63.5-3.5-3.5-3.53.5-3.53.5-3.53.63.73.43.33.43.33.2-3.3-2.8-3.32.9
Weight adjusted by age0.10.20.8-0.6-0.70.20.2-0.20.2-0.2-0.3-0.30.3-0.30.2-0.30.30.90.40.50.90.50.4-0.2-0.70.2-0.3
Bone surface1.62.93.7-1.8-1.81.71.7-1.71.7-1.7-1.7-1.71.7-1.81.7-1.81.71.71.91.71.61.81.8-1.6-1.7-1.51.1
Bone volume1.52.63.3-1.8-1.81.61.6-1.61.6-1.6-1.6-1.61.6-1.61.6-1.61.61.71.81.61.71.61.6-1.6-1.6-1.41.0
Breakpoint value in progressive ratio session0.30.41.0-0.1-0.20.60.5-0.50.5-0.6-0.6-0.60.6-0.70.6-0.60.6-0.20.70.5-0.21.01.0-0.3-0.9-0.10.7
Number of licking bursts0.40.61.61.10.9-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.7-0.7-1.3-1.0-0.8-1.3-0.6-0.60.70.60.6-0.3
Context. condit. distance diff. score0.60.71.0-0.9-1.00.80.8-0.80.8-0.8-0.8-0.80.8-0.80.8-0.80.91.00.90.81.00.80.8-0.9-0.9-0.70.4
Locomotion velocity, session 12.12.33.4-1.3-1.21.61.6-1.61.6-1.6-1.6-1.61.6-1.61.6-1.61.61.31.31.31.21.51.5-1.5-1.4-1.61.9
Locomotion distance, session 10.20.31.2-0.10.30.60.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.60.60.00.30.3-0.20.50.5-0.5-0.2-0.51.1
Locomotion velocity, session 20.00.00.1-0.10.00.20.1-0.10.1-0.1-0.2-0.20.2-0.20.2-0.20.2-0.1-0.00.1-0.20.20.2-0.1-0.2-0.00.3
Locomotion distance, session 21.11.62.3-1.3-0.91.31.3-1.31.3-1.3-1.3-1.31.3-1.31.3-1.41.30.81.01.50.81.31.3-1.2-1.3-1.31.5
Locomotion velocity, session 33.43.94.72.11.7-2.0-2.02.0-2.02.02.02.0-2.02.0-2.01.9-2.0-2.2-2.2-1.8-2.1-1.9-1.92.11.71.7-1.9
Locomotion distance, session 30.40.41.00.70.6-0.6-0.60.6-0.60.60.60.7-0.70.7-0.60.6-0.7-0.7-1.0-0.6-0.7-0.7-0.70.60.80.4-0.5
Stereotopy head waving bouts, day 30.00.00.1-0.0-0.30.00.0-0.00.1-0.0-0.1-0.10.1-0.10.0-0.10.10.00.20.10.10.20.20.1-0.30.0-0.1
Stereotopy head waving duration, day 30.60.81.41.00.7-0.9-1.00.9-0.90.90.90.9-0.90.8-0.90.8-0.8-1.0-0.4-0.8-0.9-0.5-0.51.10.41.2-1.1
Locomotion velocity, session 70.20.20.7-0.5-0.80.40.3-0.40.4-0.4-0.4-0.50.5-0.50.4-0.40.50.60.70.30.60.70.7-0.2-0.70.00.1
Locomotion distance, session 70.30.40.7-0.7-0.60.70.6-0.60.6-0.6-0.7-0.70.7-0.70.7-0.60.70.70.70.60.60.80.8-0.7-0.7-0.20.5
Stereotopy head waving bouts, day 70.50.61.0-0.9-1.00.70.7-0.70.7-0.7-0.8-0.80.8-0.80.7-0.80.70.80.80.90.90.80.8-0.7-1.0-0.60.3
Stereotopy head waving duration, day 70.20.20.5-0.6-0.70.40.4-0.40.4-0.4-0.4-0.50.5-0.50.4-0.50.50.50.70.50.50.60.6-0.4-0.7-0.2-0.0
Locomotion velocity, session 80.00.10.2-0.1-0.10.20.3-0.30.3-0.3-0.2-0.20.2-0.20.2-0.30.20.10.20.30.10.10.1-0.1-0.0-0.50.3
Locomotion distance, session 80.81.11.5-1.1-0.91.11.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.11.10.81.01.20.81.11.1-1.1-1.1-1.00.9
Degree of sensitization distance3.13.24.4-1.9-1.91.81.7-1.71.7-1.7-1.8-1.81.8-1.81.8-1.71.81.92.11.71.91.91.9-1.7-1.8-1.21.4
Degree of sensitization stereotypy0.60.60.9-0.9-0.80.80.7-0.80.7-0.8-0.8-0.80.8-0.80.8-0.80.80.70.80.90.80.80.8-0.8-1.0-0.60.4
Conditioned locomotion1.82.13.41.71.7-1.5-1.51.5-1.41.51.41.4-1.41.4-1.51.4-1.4-1.8-1.2-1.3-1.9-1.3-1.31.51.11.3-1.1
Cocaine response after cond. corrected1.61.92.2-1.5-1.21.41.4-1.41.4-1.4-1.4-1.41.4-1.41.4-1.41.41.11.31.41.21.41.4-1.4-1.5-1.41.3
Cocaine response after cond. not corrected2.12.52.9-1.7-1.41.61.6-1.61.7-1.6-1.6-1.61.6-1.61.6-1.71.61.31.41.71.41.61.5-1.5-1.7-1.61.5
Cocaine response before conditioning0.20.20.3-0.5-0.40.50.4-0.50.4-0.5-0.5-0.50.5-0.50.5-0.50.50.40.40.40.40.50.4-0.3-0.4-0.30.2
Saline control response0.00.00.10.10.1-0.1-0.10.1-0.10.10.10.1-0.10.0-0.10.1-0.1-0.2-0.1-0.1-0.20.10.00.2-0.20.3-0.2
Bone: connectivity density3.75.87.5-2.3-2.32.42.4-2.42.4-2.4-2.5-2.52.5-2.52.4-2.52.52.22.72.32.22.52.6-2.3-2.7-2.01.8
Bone: cortical apparent density0.50.71.11.10.7-0.9-0.90.9-0.90.90.90.9-0.90.9-0.90.9-0.8-0.7-1.0-1.0-0.9-0.7-0.70.90.71.0-0.6
Bone: cortical area1.21.93.11.31.0-1.4-1.41.4-1.31.41.41.4-1.41.5-1.41.4-1.5-1.1-1.2-1.4-1.1-1.5-1.61.41.80.9-1.3
Bone: cortical porosity0.30.30.8-0.6-0.60.50.4-0.50.4-0.5-0.5-0.50.5-0.50.5-0.40.50.70.90.30.60.60.6-0.5-0.6-0.1-0.1
Bone: cortical porosity0.10.10.4-0.4-0.40.30.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.30.30.50.70.20.50.30.4-0.4-0.4-0.0-0.3
Bone: cortical thickness2.74.45.02.11.7-2.2-2.22.2-2.22.22.22.2-2.22.2-2.22.2-2.2-1.7-1.9-2.2-1.8-2.1-2.22.12.21.9-2.0
Bone: cortical thickness0.10.10.30.50.6-0.2-0.30.3-0.30.20.20.2-0.20.2-0.20.2-0.2-0.40.3-0.4-0.4-0.1-0.10.20.10.4-0.2
Bone: cortical tissue density0.30.40.80.90.5-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.7-0.6-0.6-0.8-0.8-0.7-0.5-0.50.70.50.8-0.4
Condit. Reinf. active minus inactive responses0.80.91.11.10.9-0.9-1.01.0-1.00.90.90.9-0.90.9-0.90.9-0.9-0.9-1.0-0.9-0.9-0.8-0.81.00.80.9-0.9
Condit. Reinf. active-inactive response ratio0.20.20.40.50.4-0.4-0.40.4-0.50.40.40.4-0.40.4-0.40.5-0.4-0.3-0.3-0.4-0.3-0.4-0.40.50.40.5-0.6
Condit. Reinf. active responses0.00.00.30.30.1-0.1-0.10.1-0.10.10.10.1-0.10.1-0.20.1-0.2-0.3-0.5-0.2-0.3-0.1-0.10.30.00.10.1
Condit. Reinf. inactive responses0.30.41.1-0.5-0.60.60.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.70.60.30.10.60.20.60.6-0.5-0.7-0.71.1
Incentive salience index mean0.30.30.60.60.4-0.6-0.60.6-0.60.60.60.6-0.60.6-0.60.6-0.6-0.5-0.8-0.4-0.4-0.6-0.60.70.40.5-0.7
Condit. Reinf. lever presses0.20.21.1-0.6-1.00.40.4-0.40.4-0.4-0.4-0.40.4-0.40.3-0.40.40.60.10.60.70.30.3-0.3-0.5-0.4-0.1
Condit. Reinf. active minus inactive responses0.70.92.41.31.6-0.9-1.00.9-0.90.90.80.8-0.80.8-0.90.8-0.8-1.4-0.5-0.9-1.4-0.5-0.40.80.41.3-0.5
Condit. Reinf. active-inactive response ratio0.80.92.21.21.5-0.9-1.00.9-0.90.90.90.9-0.90.9-0.90.9-0.9-1.4-0.8-0.8-1.4-0.8-0.60.80.61.0-0.5
Condit. Reinf. active responses0.40.51.21.01.1-0.7-0.80.7-0.80.70.70.6-0.60.6-0.70.7-0.6-1.1-0.2-0.7-0.9-0.4-0.30.70.31.1-0.6
Condit. Reinf. inactive responses0.00.00.2-0.1-0.30.1-0.0-0.00.0-0.0-0.1-0.10.1-0.10.1-0.10.10.20.5-0.00.30.30.2-0.0-0.20.3-0.3
Condit. Reinf. lever presses2.63.65.22.12.3-1.9-1.91.9-1.91.91.91.9-1.91.9-1.91.9-1.9-2.2-1.5-1.7-2.2-1.8-1.71.91.71.8-1.5
Condit. Reinf. lever reinforcers received0.60.91.91.21.4-0.9-1.01.0-1.00.90.90.9-0.90.9-0.90.9-0.9-1.3-0.5-0.9-1.2-0.7-0.60.90.61.2-0.7
Conditioned reinforcement - actives0.30.40.6-0.6-0.70.70.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.70.70.60.80.70.40.60.7-0.6-0.8-0.70.6
Conditioned reinforcement - inactives0.10.20.7-0.5-0.40.50.6-0.50.6-0.5-0.5-0.50.5-0.50.5-0.50.40.50.40.20.30.30.3-0.4-0.1-0.90.5
Conditioned locomotion0.60.71.7-1.0-1.20.80.9-0.80.9-0.8-0.8-0.80.8-0.80.8-0.80.71.00.51.31.10.40.5-0.7-0.8-1.30.6
Patch foraging indifference point 0 sec0.40.81.31.21.0-0.9-0.90.9-0.90.90.90.9-0.90.9-0.90.9-0.9-1.0-0.7-0.9-1.0-0.8-0.70.70.81.0-0.8
Patch foraging indifference point AUC2.23.14.82.12.2-1.8-1.81.8-1.71.81.81.8-1.81.8-1.81.7-1.8-2.2-1.7-1.6-2.1-1.7-1.71.81.31.5-1.1
Delay disc. indifference point, 0s delay0.80.81.80.91.0-0.8-0.80.8-0.80.90.90.9-0.90.9-0.80.9-0.9-0.7-1.3-0.5-0.9-1.1-1.10.81.40.6-0.6
Delay disc. indifference point, 16s delay0.80.92.80.3-0.1-0.8-0.60.7-0.70.80.90.9-0.91.0-0.80.9-1.00.4-1.5-0.40.2-1.5-1.51.31.7-0.2-0.9
Delay disc. indifference point, 2s delay2.42.73.51.61.5-1.7-1.61.7-1.71.71.71.7-1.71.7-1.71.7-1.7-1.4-1.9-1.4-1.2-1.7-1.71.71.81.4-1.5
Delay disc. indifference point, 24s delay0.80.92.0-1.1-1.20.90.9-0.90.9-0.9-0.9-0.90.9-0.90.9-0.90.91.30.70.91.40.80.8-0.7-0.9-0.90.6
Delay disc. indifference point, 4s delay0.20.20.60.40.0-0.3-0.30.3-0.30.30.40.4-0.40.4-0.30.4-0.4-0.2-0.7-0.60.3-0.6-0.60.70.80.1-0.7
Delay disc. indifference point, 8s delay0.60.71.60.40.1-0.8-0.70.8-0.70.80.80.9-0.90.9-0.80.8-0.90.0-1.2-0.3-0.0-1.3-1.31.20.90.1-0.9
Indifference point function ln k0.50.82.0-1.2-1.40.90.9-0.90.8-0.9-0.9-0.90.9-0.90.9-0.80.91.30.80.51.21.01.0-0.9-0.5-0.50.5
Indifference point function log k0.50.82.0-1.2-1.40.90.9-0.90.8-0.9-0.9-0.90.9-0.90.9-0.80.91.30.80.51.21.01.0-0.9-0.5-0.50.5
Patch foraging total patch changes 0 sec0.40.71.11.10.9-0.8-0.90.8-0.90.80.80.8-0.80.8-0.80.8-0.8-0.9-0.6-0.9-0.9-0.6-0.60.70.71.0-0.7
Patch foraging total patch changes 12 sec0.20.31.20.91.1-0.5-0.40.4-0.40.40.40.5-0.50.5-0.50.4-0.5-0.9-0.4-0.4-0.9-0.5-0.50.40.50.10.1
Patch foraging total patch changes 18 sec1.82.74.72.12.2-1.7-1.71.7-1.61.61.61.6-1.61.6-1.71.6-1.6-2.0-1.4-1.6-2.0-1.5-1.41.51.51.5-1.0
Patch foraging total patch changes 24 sec2.03.56.22.32.5-1.9-1.91.9-1.91.91.81.8-1.81.8-1.91.8-1.8-2.4-1.7-1.7-2.2-1.7-1.61.81.41.7-1.0
Patch foraging total patch changes 6 sec3.24.96.62.52.6-2.2-2.22.2-2.22.22.22.2-2.22.3-2.22.2-2.2-2.5-2.3-1.9-2.4-2.3-2.22.12.11.8-1.7
Patch foraging time to switch 0 sec1.32.73.1-1.7-1.81.71.7-1.71.7-1.7-1.7-1.71.7-1.71.7-1.71.71.71.41.71.71.51.4-1.4-1.5-1.81.4
Patch foraging water rate 0 sec1.53.25.02.02.2-1.8-1.81.8-1.81.81.81.8-1.81.8-1.81.8-1.8-2.0-1.3-1.8-2.1-1.6-1.51.51.81.8-1.5
Patch foraging water rate 12 sec0.10.20.7-0.4-0.40.40.4-0.40.3-0.4-0.4-0.40.4-0.40.4-0.40.50.60.80.20.50.60.7-0.8-0.3-0.00.3
Patch foraging water rate 18 sec0.50.81.5-1.2-1.00.80.8-0.80.8-0.8-0.8-0.80.8-0.80.8-0.70.81.21.10.81.20.80.9-1.0-0.6-0.60.5
Patch foraging water rate 24 sec0.20.20.70.50.6-0.4-0.40.4-0.40.40.40.4-0.40.5-0.40.4-0.5-0.4-0.5-0.5-0.5-0.6-0.50.20.90.2-0.4
Patch foraging water rate 6 sec1.11.62.31.21.2-1.3-1.31.3-1.41.31.31.3-1.31.3-1.31.3-1.3-1.0-0.9-1.5-1.2-1.1-1.11.11.41.4-1.2
Seeking ratio, delayed vs. immediate footshock1.72.13.21.51.6-1.4-1.41.4-1.41.41.51.5-1.51.5-1.41.5-1.5-1.4-1.7-1.3-1.2-1.7-1.81.41.41.0-1.3
Distance traveled before self-admin3.24.25.61.91.5-2.2-2.22.2-2.22.22.22.2-2.22.2-2.22.2-2.2-1.3-2.2-2.2-1.3-2.2-2.21.81.92.0-2.4
Distance traveled after self-admin0.10.10.30.1-0.2-0.3-0.30.3-0.30.30.30.3-0.30.3-0.30.3-0.30.2-0.5-0.20.2-0.4-0.4-0.00.20.2-0.5
Extensor digitorum longus weight0.93.44.8-2.2-2.11.81.8-1.81.8-1.8-1.8-1.81.8-1.81.8-1.81.82.02.12.12.21.71.7-1.7-1.6-1.71.2
Bone: elastic displacement2.93.33.61.81.6-1.9-1.91.9-1.91.91.91.9-1.91.9-1.91.9-1.9-1.7-1.7-1.8-1.7-1.9-1.81.81.91.6-1.9
Bone: elastic work8.411.013.03.63.1-3.4-3.33.4-3.33.43.43.4-3.43.4-3.43.4-3.4-3.1-3.1-3.6-3.1-3.3-3.33.43.62.9-3.0
Bone: endosteal estimation0.00.00.1-0.10.20.10.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.1-0.10.10.1-0.1-0.2-0.0-0.10.3-0.30.0
Bone: endosteal perimeter0.00.10.5-0.3-0.10.30.3-0.30.4-0.3-0.3-0.20.2-0.20.3-0.30.20.10.20.30.10.00.0-0.20.2-0.70.3
Epididymis fat weight8.328.435.7-6.0-5.65.45.4-5.45.4-5.4-5.4-5.45.4-5.45.4-5.35.45.85.45.35.55.25.1-5.2-4.7-4.84.5
Delta time in closed arm before/after self-admin3.02.84.81.21.0-1.8-1.81.8-1.81.81.81.8-1.81.7-1.81.8-1.7-0.8-1.8-1.8-0.8-1.6-1.61.71.61.9-2.2
Delta time in open arm before/after self-admin6.36.211.4-1.8-1.32.62.7-2.72.7-2.7-2.6-2.62.6-2.62.6-2.72.51.22.42.71.22.32.3-2.6-2.5-2.93.4
Diff in mean of infusions in LGA sessions0.50.61.3-0.5-0.50.90.9-0.90.9-0.9-0.9-0.90.9-0.90.9-0.90.80.20.40.90.20.80.8-0.7-0.7-0.81.1
Delay discount exponential model param0.91.02.2-0.6-0.31.00.8-0.90.9-0.9-1.0-1.01.0-1.11.0-1.01.00.21.50.7-0.01.41.4-1.4-1.4-0.31.1
Extinction: sum of active levers before priming0.80.91.4-0.6-0.81.00.9-0.90.9-1.0-1.0-1.01.0-1.00.9-1.00.90.51.01.00.51.21.2-0.9-1.2-0.91.2
Active lever presses in extinction session 60.20.21.1-0.4-0.40.30.2-0.20.2-0.3-0.3-0.40.3-0.40.2-0.40.40.61.10.20.60.80.8-0.8-0.70.3-0.1
Bone: final force0.20.40.80.70.3-0.6-0.60.6-0.60.60.60.6-0.60.6-0.60.6-0.7-0.4-0.6-0.7-0.5-0.8-0.80.60.90.3-0.7
Bone: final moment0.30.40.90.60.4-0.7-0.60.6-0.60.70.70.7-0.70.7-0.70.7-0.7-0.4-0.6-0.8-0.5-0.8-0.80.71.00.3-0.8
Food consumed during 24 hour testing period0.30.41.20.40.4-0.6-0.70.7-0.70.70.60.6-0.60.6-0.60.7-0.6-0.1-0.1-1.0-0.1-0.3-0.30.80.51.1-1.1
Glucose1.32.02.51.41.4-1.5-1.51.5-1.51.51.51.5-1.51.5-1.51.5-1.5-1.3-1.0-1.4-1.2-1.5-1.41.61.21.3-1.2
Heart weight1.32.12.9-1.5-1.51.51.4-1.51.5-1.5-1.5-1.51.5-1.51.5-1.51.61.41.71.31.21.71.6-1.2-1.3-1.01.0
Delay discount hyperbolic model param1.31.52.8-0.9-0.61.21.1-1.21.1-1.2-1.2-1.31.3-1.31.2-1.31.30.51.70.90.31.61.6-1.6-1.6-0.61.3
Intermittent access intake day 1-15 change0.00.10.5-0.20.00.20.1-0.10.1-0.1-0.2-0.20.2-0.20.2-0.10.20.10.4-0.0-0.00.40.4-0.2-0.70.40.0
Intermittent access intake escalation0.10.10.6-0.3-0.00.30.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.30.40.20.40.20.00.50.5-0.2-0.80.10.3
Intermittent access intake escalation 20.10.20.30.30.5-0.4-0.40.4-0.40.40.40.4-0.40.4-0.40.4-0.4-0.3-0.4-0.5-0.4-0.3-0.30.4-0.00.5-0.4
Intermitt. access day 1 inactive lever presses0.00.10.30.30.4-0.3-0.30.4-0.30.40.40.4-0.40.4-0.40.3-0.4-0.3-0.4-0.4-0.6-0.4-0.40.50.50.2-0.4
Intermitt. access day 15 inactive lever presses0.51.03.51.31.9-0.8-0.80.8-0.80.80.80.8-0.80.8-0.80.8-0.8-1.7-0.5-0.9-1.8-0.8-0.71.00.80.8-0.3
Intermitt. access escalation Index1.01.52.7-1.5-1.61.21.2-1.21.2-1.2-1.1-1.11.1-1.11.2-1.01.21.50.71.61.70.90.9-1.4-0.8-1.01.0
Intermittent access day 1 total infusions0.20.41.7-0.5-0.40.60.7-0.70.7-0.6-0.6-0.60.6-0.60.6-0.70.50.30.41.10.30.20.3-0.4-0.3-1.30.9
Intermittent access day 15 total infusions0.91.42.4-0.9-0.61.21.3-1.21.3-1.2-1.2-1.21.2-1.21.2-1.31.20.61.11.60.51.01.1-1.1-1.4-1.51.5
Intermittent access terminal intake (last 3 days)1.21.62.7-1.1-1.01.31.4-1.31.4-1.3-1.3-1.31.3-1.31.3-1.31.20.91.11.50.91.01.1-1.2-1.4-1.61.4
Intermittent access total infusions0.50.61.7-0.6-0.40.80.8-0.80.9-0.8-0.8-0.80.8-0.70.8-0.80.70.30.71.30.30.50.5-0.6-1.0-1.21.0
Intermittent access day 1 locomotion0.10.11.0-0.3-0.40.30.4-0.30.4-0.3-0.3-0.30.3-0.20.3-0.40.20.2-0.10.80.2-0.10.0-0.1-0.2-1.00.5
Intermittent access day 15 total locomotion0.40.71.2-0.8-0.90.80.8-0.80.9-0.8-0.8-0.80.8-0.80.8-0.90.70.80.71.10.80.70.8-0.7-1.0-1.00.6
Intermittent access total locomotion0.70.81.7-0.8-0.70.91.0-0.91.0-0.9-0.9-0.90.9-0.90.9-1.00.80.70.71.30.70.70.8-0.6-1.1-1.31.0
Intermittent access standard deviation0.00.10.30.20.50.10.2-0.10.2-0.1-0.1-0.10.1-0.10.1-0.10.1-0.40.30.3-0.4-0.2-0.1-0.1-0.2-0.50.6
Left kidney weight0.00.20.4-0.6-0.60.50.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.50.50.60.40.40.50.40.3-0.4-0.0-0.50.3
Right kidney weight0.20.81.0-1.0-1.00.90.9-0.90.9-0.9-0.9-0.90.9-0.90.9-0.90.91.01.00.90.90.80.8-0.8-0.5-0.90.7
Cocaine induced anxiety0.20.20.90.60.8-0.4-0.40.4-0.40.40.40.4-0.40.4-0.40.4-0.4-0.8-0.5-0.3-0.9-0.5-0.50.40.70.3-0.1
Post-drug Anxiety0.10.10.3-0.2-0.00.30.3-0.30.2-0.3-0.3-0.30.3-0.40.3-0.30.40.00.50.3-0.00.50.5-0.3-0.60.10.3
Baseline Anxiety0.20.31.2-0.3-0.30.40.3-0.40.3-0.4-0.4-0.50.5-0.50.4-0.40.50.30.80.20.80.80.8-0.4-1.10.20.2
Tail length0.41.52.1-1.3-1.11.31.2-1.31.2-1.3-1.3-1.31.3-1.31.3-1.21.31.41.40.81.31.41.3-1.2-1.0-0.81.1
Length with tail0.62.53.6-1.7-1.51.71.6-1.61.6-1.6-1.6-1.61.6-1.61.7-1.51.71.91.81.21.71.61.5-1.5-1.1-1.41.4
Length without tail0.41.42.5-1.4-1.31.21.3-1.21.2-1.2-1.2-1.21.2-1.11.2-1.11.21.61.21.11.30.91.0-1.1-0.7-1.31.1
Times rat made contact with spout0.10.10.7-0.0-0.0-0.3-0.40.3-0.40.30.30.3-0.30.3-0.30.3-0.30.30.3-0.60.30.0-0.10.50.10.7-0.8
Lifetime Intake0.80.92.5-0.7-0.61.01.1-1.01.1-1.0-1.0-0.90.9-0.91.0-1.00.90.50.81.40.50.50.6-0.8-1.0-1.61.3
Liver weight, left5.28.510.4-3.1-2.92.92.9-2.92.9-2.9-2.9-2.92.9-2.92.9-2.92.92.93.22.83.02.92.8-2.9-2.9-2.62.7
Liver weight, right4.06.97.9-2.8-2.72.72.7-2.72.7-2.7-2.7-2.72.7-2.72.7-2.72.72.62.82.62.62.62.6-2.5-2.4-2.52.3
Locomotor activity0.00.10.70.40.8-0.2-0.20.2-0.20.20.20.2-0.20.2-0.10.2-0.2-0.40.1-0.2-0.4-0.2-0.10.10.20.20.1
Locomotor testing distance0.10.10.70.40.9-0.3-0.30.3-0.30.30.30.3-0.30.3-0.30.4-0.3-0.5-0.1-0.2-0.4-0.4-0.30.20.20.20.0
Locomotor testing rearing0.10.21.30.71.1-0.4-0.40.4-0.40.40.40.3-0.30.3-0.30.4-0.3-0.80.0-0.5-0.7-0.2-0.20.4-0.00.60.0
Locomotion in novel chamber1.92.53.91.10.9-1.7-1.61.7-1.61.71.71.7-1.81.8-1.71.7-1.7-0.4-1.9-1.5-0.4-1.9-1.91.31.31.2-2.0
Locomotion in novel chamber post-restriction0.10.10.8-0.4-0.90.00.0-0.00.0-0.0-0.0-0.00.0-0.00.0-0.00.00.70.0-0.20.60.2-0.2-0.1-0.7-0.0-0.4
Fecal boli incidents, locomotor time 11.42.03.4-1.4-1.31.41.3-1.41.3-1.4-1.4-1.41.4-1.41.4-1.41.41.11.71.41.21.61.9-1.7-1.7-0.91.3
Change in fecal boli incidents, locomotor task0.10.10.50.30.0-0.2-0.10.1-0.10.20.20.2-0.20.3-0.20.2-0.3-0.1-0.7-0.20.2-0.6-0.60.40.7-0.4-0.3
Time >=10cm from walls, locomotor time 10.00.00.1-0.0-0.10.20.2-0.20.1-0.2-0.2-0.20.2-0.20.2-0.20.20.10.30.30.10.20.10.0-0.3-0.1-0.1
Bouts of movement, locomotor time 10.40.50.80.70.6-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.7-0.7-0.5-0.9-0.6-0.5-0.8-0.80.70.90.5-0.7
Total resting periods, locomotor time 10.10.10.20.50.4-0.4-0.40.4-0.40.40.40.4-0.40.4-0.40.4-0.4-0.4-0.5-0.3-0.2-0.3-0.40.30.50.4-0.4
Rest time, locomotor task time 10.10.20.6-0.10.10.30.2-0.30.3-0.3-0.3-0.40.4-0.40.3-0.40.4-0.40.7-0.0-0.20.60.4-0.8-0.80.10.2
Distance moved, locomotor task time 10.20.30.80.50.3-0.5-0.40.5-0.50.50.50.6-0.50.6-0.50.6-0.6-0.2-0.8-0.4-0.3-0.8-0.90.80.90.1-0.5
Vertical activity count, locomotor time 10.00.10.40.30.1-0.1-0.00.1-0.00.10.20.2-0.20.2-0.10.2-0.2-0.2-0.60.20.1-0.6-0.60.40.6-0.5-0.1
Time >=10cm from walls, locomotor time 20.81.11.6-0.6-0.71.21.2-1.21.2-1.2-1.2-1.21.2-1.11.2-1.11.10.21.11.30.91.00.9-1.0-1.0-1.31.0
Bouts of movement, locomotor time 20.30.51.30.90.7-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.7-0.7-0.9-0.7-1.1-0.5-0.6-0.50.70.90.7-0.7
Total resting periods, locomotor time 20.10.20.80.50.4-0.4-0.40.4-0.40.40.40.4-0.40.4-0.40.4-0.4-0.5-0.3-0.9-0.3-0.2-0.20.40.50.6-0.5
Rest time, locomotor task time 20.20.21.30.50.8-0.3-0.50.4-0.40.40.30.2-0.20.2-0.30.2-0.2-0.70.4-0.5-0.80.40.3-0.1-0.61.1-0.4
Distance moved, locomotor task time 20.20.21.00.1-0.1-0.3-0.20.2-0.20.30.30.4-0.40.4-0.30.4-0.40.2-0.80.0-0.0-0.9-1.00.50.8-0.5-0.3
Vertical activity count, locomotor time 20.20.31.70.2-0.1-0.20.00.1-0.00.20.30.4-0.40.4-0.20.4-0.4-0.0-1.10.10.1-1.2-1.30.61.2-1.0-0.1
Light reinforcement 10.00.00.00.00.0-0.1-0.00.0-0.00.10.10.1-0.10.1-0.10.1-0.10.0-0.20.20.1-0.2-0.10.00.1-0.1-0.0
Light reinforcement 20.30.40.60.60.5-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.7-0.7-0.5-0.4-0.7-0.5-0.7-0.80.60.80.5-0.7
Bone: marrow area0.00.00.1-0.10.20.10.1-0.10.1-0.1-0.1-0.10.1-0.00.1-0.10.0-0.10.10.0-0.1-0.2-0.1-0.00.4-0.30.0
Bone: maximum diameter0.20.51.20.50.4-0.7-0.60.6-0.60.70.70.7-0.70.7-0.70.7-0.7-0.5-0.6-0.6-0.6-0.9-0.90.71.10.2-0.7
Bone: maximum force0.40.71.40.80.6-0.9-0.80.8-0.80.90.90.9-0.90.9-0.90.9-0.9-0.6-0.8-0.9-0.6-1.0-1.00.91.20.5-0.9
Bone: maximum moment0.50.91.60.80.6-0.9-0.90.9-0.90.91.01.0-1.01.0-1.01.0-1.0-0.6-0.7-1.0-0.6-1.1-1.10.91.30.6-1.0
Mean time between licks in bursts0.41.11.8-1.2-1.31.01.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.01.01.31.00.91.30.90.8-0.9-0.9-1.10.8
Mean num. licks in bursts0.40.72.4-1.2-1.10.60.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.60.61.61.30.51.60.70.6-0.6-0.6-0.3-0.1
Cd content in liver0.80.92.21.21.4-0.8-0.70.8-0.70.80.80.8-0.80.9-0.80.8-0.9-1.5-1.3-0.6-1.4-1.0-1.00.91.10.3-0.1
Co content in liver0.50.51.70.81.2-0.7-0.70.7-0.70.70.70.7-0.70.7-0.60.7-0.6-1.1-0.8-0.3-1.3-0.6-0.60.60.50.8-0.4
Cu content in liver1.82.23.11.61.8-1.5-1.51.5-1.51.51.51.4-1.41.4-1.51.4-1.4-1.6-1.4-1.5-1.5-1.2-1.21.51.51.6-1.3
Fe content in liver2.22.64.2-1.2-1.11.71.7-1.71.8-1.7-1.7-1.71.7-1.71.7-1.81.60.71.81.60.81.61.6-1.5-1.6-2.02.1
K content in liver0.10.10.3-0.3-0.30.40.4-0.40.4-0.4-0.3-0.30.3-0.30.4-0.30.40.4-0.10.40.40.30.3-0.3-0.3-0.30.5
Mg content in liver0.80.81.91.21.2-0.8-0.80.8-0.80.80.80.8-0.80.8-0.80.8-0.8-1.4-1.0-1.0-1.4-0.7-0.71.00.80.7-0.5
Mn content in liver0.30.30.50.60.6-0.6-0.60.6-0.60.60.50.5-0.50.5-0.50.6-0.5-0.6-0.7-0.5-0.6-0.4-0.40.50.40.7-0.3
Na content in liver0.20.21.2-0.3-0.10.40.5-0.50.5-0.4-0.4-0.40.4-0.30.4-0.40.30.3-0.20.60.3-0.1-0.1-0.3-0.1-1.10.9
Rb content in liver0.10.10.20.00.10.30.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.30.3-0.30.20.4-0.30.20.2-0.3-0.3-0.20.5
Se content in liver0.91.14.21.61.4-0.9-0.90.9-0.80.80.80.8-0.80.8-0.90.8-0.9-2.1-1.1-1.0-2.0-0.7-0.71.00.80.60.1
Sr content in liver0.30.30.6-0.7-0.40.60.5-0.50.4-0.5-0.5-0.50.6-0.50.6-0.40.60.80.40.50.60.70.7-0.6-0.70.00.3
Zn content in liver0.40.41.4-0.2-0.20.70.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.70.6-0.20.40.4-0.10.70.7-0.6-0.5-1.01.2
Bone: minimum diameter0.00.10.30.10.1-0.3-0.20.3-0.20.30.30.3-0.30.3-0.30.3-0.3-0.20.0-0.2-0.2-0.4-0.40.30.6-0.1-0.2
Time in familiar zone, hab. session 10.30.30.40.30.3-0.5-0.50.5-0.50.50.60.6-0.60.6-0.50.6-0.6-0.2-0.6-0.4-0.2-0.6-0.60.50.70.5-0.6
Time in novel zone, hab. session 10.10.10.3-0.1-0.10.40.3-0.30.3-0.4-0.4-0.40.4-0.40.4-0.40.40.10.40.20.10.50.5-0.3-0.5-0.30.5
Total zone transitions, hab. session 10.00.00.30.00.1-0.1-0.10.1-0.10.10.10.1-0.10.1-0.10.1-0.1-0.1-0.50.0-0.2-0.3-0.30.10.4-0.10.2
Total locomotion distance, hab. session 10.10.10.30.30.2-0.4-0.40.4-0.40.40.40.4-0.40.4-0.30.4-0.3-0.3-0.6-0.4-0.3-0.3-0.30.30.40.5-0.2
Locomotion velocity, hab. session 10.30.40.90.60.6-0.7-0.70.7-0.70.70.70.7-0.70.7-0.70.7-0.6-0.6-0.9-0.7-0.7-0.7-0.70.60.70.6-0.4
Time in familiar zone, hab. session 20.20.30.70.70.8-0.5-0.50.5-0.50.50.50.5-0.50.5-0.50.5-0.5-0.7-0.1-0.5-0.7-0.3-0.30.50.20.7-0.3
Time in novel zone, hab. session 20.10.10.40.2-0.1-0.3-0.20.2-0.20.20.30.3-0.30.3-0.30.3-0.3-0.0-0.6-0.3-0.0-0.5-0.50.20.5-0.1-0.2
Total zone transitions, hab. session 20.30.30.8-0.8-0.60.60.6-0.60.6-0.6-0.6-0.60.6-0.60.6-0.60.60.40.20.90.40.60.6-0.5-0.5-0.60.7
Total locomotion distance, hab. session 20.10.10.50.30.6-0.3-0.40.3-0.40.30.30.3-0.30.3-0.30.3-0.3-0.7-0.3-0.2-0.7-0.2-0.20.40.20.5-0.0
Locomotion velocity, hab. session 20.10.20.50.30.7-0.4-0.40.4-0.40.40.40.4-0.40.3-0.40.3-0.3-0.7-0.4-0.2-0.7-0.2-0.20.50.30.5-0.1
Novel to familiar place preference ratio0.91.01.1-1.0-1.01.01.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.01.01.11.11.01.10.90.9-1.0-0.9-1.00.9
Novelty place preference1.21.21.4-1.2-1.21.11.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.11.11.21.11.11.21.11.1-1.2-1.0-1.11.0
Time in novel zone, NPP test1.21.31.5-1.2-1.21.21.2-1.21.2-1.2-1.2-1.21.2-1.21.2-1.21.21.21.11.11.21.11.1-1.2-1.1-1.11.0
Total zone transitions, NPP test0.00.00.30.00.30.10.2-0.20.2-0.2-0.1-0.10.1-0.10.1-0.20.1-0.3-0.20.3-0.30.10.1-0.1-0.0-0.30.5
Total locomotion distance, NPP test1.01.42.61.31.6-1.1-1.11.1-1.11.11.11.1-1.11.1-1.11.1-1.1-1.6-1.3-1.0-1.6-1.0-1.01.21.11.0-0.5
Locomotion velocity, NPP test1.21.62.91.41.7-1.2-1.21.2-1.21.21.21.2-1.21.2-1.21.2-1.2-1.7-1.4-1.1-1.7-1.2-1.21.31.21.1-0.7
Intraocular pressure1.11.61.81.21.0-1.3-1.31.3-1.31.31.31.3-1.31.3-1.31.3-1.3-1.1-1.0-1.2-1.1-1.3-1.21.31.11.3-1.2
Delta distance traveled before/after self-admin3.03.13.6-1.7-1.51.81.8-1.81.8-1.8-1.8-1.81.8-1.81.8-1.91.81.51.81.91.51.81.8-1.7-1.7-1.81.9
Delta ambulatory time before/after self-admin2.02.54.5-1.2-0.81.71.7-1.71.7-1.7-1.7-1.71.7-1.71.7-1.71.60.71.61.80.71.61.6-1.4-1.5-1.82.1
Parametrial fat weight6.014.117.2-4.1-3.83.83.8-3.83.8-3.8-3.8-3.83.8-3.83.8-3.83.93.84.13.83.63.83.8-3.5-3.6-3.23.1
Pavlov. Cond. lever latency0.00.00.10.00.20.10.0-0.10.0-0.1-0.1-0.10.1-0.10.1-0.10.1-0.00.4-0.1-0.10.20.2-0.1-0.00.10.4
Pavlov. Cond. magazine entry latency0.00.00.1-0.2-0.20.20.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.20.20.1-0.00.30.10.10.1-0.2-0.1-0.40.3
Pavlov. Cond. change in total contacts0.30.30.60.40.4-0.6-0.60.6-0.60.60.60.6-0.60.6-0.60.5-0.6-0.6-0.7-0.3-0.5-0.6-0.60.70.40.4-0.6
Pavlov. Cond. index score0.00.00.1-0.1-0.1-0.1-0.00.1-0.00.10.10.1-0.10.1-0.10.1-0.1-0.1-0.30.2-0.0-0.2-0.20.10.1-0.2-0.2
Pavlov. Cond. latency score0.00.00.1-0.1-0.20.00.1-0.10.1-0.1-0.0-0.00.0-0.00.0-0.10.00.0-0.20.20.1-0.1-0.1-0.0-0.1-0.3-0.0
Pavlov. Cond. lever contacts0.00.00.1-0.3-0.30.00.1-0.10.1-0.1-0.0-0.00.0-0.00.0-0.0-0.00.1-0.30.40.3-0.2-0.20.0-0.1-0.3-0.2
Pavlov. Cond. magazine entry number0.10.10.3-0.3-0.30.40.3-0.30.3-0.4-0.4-0.40.4-0.40.4-0.30.40.40.50.20.40.50.5-0.4-0.4-0.10.3
Pavlov. Cond. intertrial magazine entries0.30.40.80.80.8-0.6-0.60.6-0.60.60.50.5-0.50.5-0.60.5-0.6-0.8-0.7-0.6-0.9-0.4-0.40.50.50.6-0.3
Pavlov. Cond. lever-magazine prob. diff.0.00.00.20.10.1-0.2-0.20.2-0.10.20.20.2-0.20.2-0.20.2-0.2-0.3-0.40.1-0.2-0.4-0.40.20.2-0.1-0.3
Pavlov. Cond. response bias0.00.00.1-0.1-0.1-0.00.1-0.00.1-0.00.00.0-0.00.0-0.0-0.0-0.0-0.1-0.30.20.0-0.2-0.20.00.1-0.3-0.1
Pavlov. Cond. lever latency2.63.55.6-2.1-2.41.91.9-1.91.9-1.9-1.9-1.91.9-1.91.9-1.91.92.11.31.82.21.81.7-1.9-1.8-1.81.3
Pavlov. Cond. magazine entry latency0.20.20.40.60.6-0.5-0.50.5-0.50.50.50.5-0.50.5-0.50.5-0.5-0.5-0.4-0.6-0.5-0.4-0.50.60.40.4-0.3
Pavlov. Cond. change in total contacts1.42.23.81.82.0-1.5-1.51.5-1.51.51.51.5-1.51.5-1.51.4-1.5-1.7-1.2-1.5-1.8-1.4-1.41.51.41.3-0.9
Pavlov. Cond. index score2.33.25.02.02.2-1.8-1.81.8-1.81.81.81.8-1.81.8-1.81.8-1.8-2.0-1.3-1.8-2.0-1.6-1.71.91.71.6-1.2
Pavlov. Cond. latency score2.83.75.82.22.4-1.9-1.91.9-1.91.91.91.9-1.91.9-1.91.9-1.9-2.1-1.4-1.9-2.1-1.8-1.82.01.81.8-1.3
Pavlov. Cond. lever contacts1.52.13.81.71.9-1.5-1.51.5-1.51.51.41.4-1.41.4-1.41.4-1.4-1.8-0.9-1.4-1.8-1.3-1.21.51.31.5-1.0
Pavlov. Cond. magazine entry number0.00.10.4-0.4-0.60.10.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.10.4-0.00.20.40.10.2-0.3-0.1-0.1-0.2
Pavlov. Cond. intertrial magazine entries0.40.61.0-0.9-1.00.80.8-0.80.8-0.8-0.8-0.80.8-0.80.8-0.80.80.80.50.80.80.80.9-0.9-0.8-0.60.6
Pavlov. Cond. lever-magazine prob. diff.1.82.44.11.82.0-1.5-1.61.5-1.51.51.51.5-1.51.5-1.51.5-1.5-1.8-1.1-1.5-1.8-1.4-1.51.61.41.4-1.0
Pavlov. Cond. response bias1.21.72.81.51.7-1.3-1.31.3-1.31.31.31.3-1.31.3-1.31.3-1.3-1.5-1.0-1.3-1.6-1.2-1.21.31.21.2-0.7
Time in closed arm before self-admin1.62.03.3-1.3-1.31.51.6-1.51.5-1.5-1.5-1.41.4-1.41.5-1.51.41.11.11.61.11.11.1-1.4-1.4-1.81.7
Time in closed arm after self-admin0.60.61.5-0.1-0.3-0.7-0.60.7-0.60.70.80.8-0.80.8-0.70.8-0.80.6-1.1-0.70.6-1.2-1.20.51.10.3-1.2
Time in open arm before self-admin2.32.54.81.41.4-1.6-1.71.7-1.71.71.61.6-1.61.6-1.61.6-1.5-1.2-1.1-1.8-1.2-1.1-1.11.91.42.2-2.0
Time in open arm after self-admin0.91.02.0-0.5-0.01.01.0-1.01.0-1.0-1.0-1.11.0-1.01.0-1.11.00.11.31.00.11.11.1-0.9-1.1-1.01.4
Bone: periosteal estimation0.30.61.50.70.7-0.8-0.70.7-0.70.70.80.8-0.80.8-0.80.8-0.8-0.7-0.6-0.8-0.7-1.0-1.00.81.20.3-0.7
Bone: periosteal perimeter0.20.31.20.30.2-0.5-0.40.5-0.40.50.50.6-0.60.6-0.50.5-0.6-0.2-0.5-0.5-0.3-0.8-0.90.61.1-0.1-0.5
Bone: post-yield work0.40.61.7-1.2-1.30.70.7-0.70.7-0.7-0.7-0.70.7-0.70.7-0.70.61.10.60.91.10.50.5-0.6-0.6-0.80.3
Progressive ratio test 1 active lever presses0.40.51.10.80.8-0.6-0.60.6-0.60.60.60.7-0.60.7-0.60.7-0.7-0.9-0.8-0.3-1.1-0.9-0.80.80.40.3-0.2
Progressive ratio test 1 breakpoint0.50.61.40.90.9-0.7-0.60.7-0.60.70.70.7-0.70.7-0.70.7-0.7-1.0-0.8-0.3-1.2-1.0-0.90.80.50.3-0.2
Progressive ratio test 1 inactive lever presses1.21.73.01.41.2-1.3-1.21.2-1.21.31.31.3-1.31.4-1.31.3-1.4-1.4-1.5-1.0-1.4-1.7-1.61.41.50.6-0.8
Progressive ratio test 2 active lever presses0.30.30.70.70.7-0.6-0.60.6-0.60.60.60.6-0.60.6-0.60.5-0.6-0.7-0.4-0.3-0.9-0.6-0.60.60.40.4-0.4
Progressive ratio test 2 breakpoint0.30.30.80.70.8-0.6-0.60.6-0.50.60.60.6-0.60.6-0.60.5-0.6-0.8-0.4-0.3-0.9-0.6-0.50.60.30.4-0.4
Progressive ratio test 2 inactive lever presses0.10.10.30.30.5-0.3-0.30.3-0.30.30.30.3-0.30.3-0.30.3-0.3-0.2-0.0-0.3-0.3-0.4-0.40.40.40.1-0.4
Incentive Sensitization - Responses0.00.00.2-0.1-0.00.10.0-0.00.1-0.1-0.1-0.10.1-0.10.0-0.20.00.00.40.1-0.10.20.30.0-0.1-0.1-0.1
Incentive Sensitization - Breakpoint0.00.00.3-0.1-0.00.10.1-0.10.1-0.1-0.1-0.20.2-0.20.1-0.20.10.00.50.2-0.00.30.3-0.0-0.2-0.1-0.0
Sum of active levers in priming session hrs 5-61.41.32.0-0.8-0.71.21.1-1.21.2-1.2-1.2-1.21.2-1.21.2-1.21.20.51.21.20.51.31.3-1.1-1.2-1.01.4
Progressive ratio0.00.10.30.20.20.0-0.10.0-0.10.0-0.0-0.10.1-0.10.0-0.10.1-0.30.5-0.2-0.30.40.5-0.2-0.50.6-0.3
Food seeking constrained by brief footshock0.10.10.2-0.2-0.10.30.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.30.3-0.10.40.2-0.10.40.3-0.4-0.2-0.30.5
Seeking ratio, punishment vs. effort0.10.10.4-0.1-0.2-0.10.00.1-0.00.10.10.2-0.20.2-0.10.2-0.20.3-0.50.10.2-0.4-0.60.20.5-0.50.2
Retroperitoneal fat weight0.62.53.9-1.9-1.71.61.6-1.61.6-1.6-1.6-1.61.6-1.61.6-1.51.62.01.91.61.81.41.4-1.4-1.2-1.51.3
Reaction time number correct0.71.31.6-1.2-0.91.21.2-1.21.1-1.2-1.2-1.21.2-1.21.2-1.11.21.11.31.10.91.11.1-1.3-1.0-1.00.9
Reaction time mean minus median0.10.30.8-0.3-0.20.50.5-0.50.5-0.5-0.5-0.50.5-0.50.5-0.50.50.20.30.40.20.60.6-0.5-0.7-0.40.9
Reaction time mean minus median AUC0.92.33.9-1.4-1.31.61.6-1.61.6-1.6-1.6-1.61.6-1.51.6-1.61.51.31.31.51.31.41.4-1.6-1.6-1.62.0
Reaction time num false alarms5.67.98.62.82.6-2.9-2.92.9-2.92.92.92.9-2.92.9-2.92.9-2.9-2.5-2.4-2.8-2.6-2.7-2.72.72.72.9-2.9
Reaction time num false alarms AUC5.18.08.92.82.6-2.9-3.03.0-3.03.02.92.9-2.92.9-2.93.0-2.9-2.5-2.3-2.8-2.7-2.8-2.72.72.82.9-3.0
Reaction time trials correct on left0.71.31.6-1.2-0.91.21.2-1.21.1-1.2-1.2-1.21.2-1.21.2-1.11.21.11.31.10.91.11.1-1.3-1.0-1.00.9
Reaction time trials on left0.71.31.6-1.3-0.91.21.2-1.21.2-1.2-1.2-1.21.2-1.21.2-1.21.21.21.31.11.01.11.1-1.3-1.0-1.00.9
Reaction time mean0.50.81.7-0.7-0.61.01.0-1.01.0-1.0-1.0-1.01.0-1.01.0-1.01.00.60.70.70.51.01.0-0.9-1.0-0.91.3
Reaction time mean AUC0.40.71.5-0.6-0.50.90.9-0.90.9-0.9-0.9-0.90.9-0.90.9-0.90.90.50.60.60.50.90.8-0.8-0.8-0.91.2
Median of all reaction times0.40.61.3-0.4-0.30.80.8-0.80.8-0.8-0.8-0.80.8-0.80.8-0.90.80.30.60.50.20.90.8-0.7-0.8-0.81.1
Reaction time omissions1.42.03.5-1.6-1.91.41.4-1.41.4-1.4-1.4-1.41.4-1.41.4-1.41.41.71.11.41.81.31.3-1.4-1.5-1.31.1
Reaction time false alarm rate6.08.29.02.92.5-3.0-3.03.0-3.03.03.03.0-3.03.0-3.03.0-2.9-2.6-2.6-2.9-2.6-2.8-2.82.82.82.9-2.9
Reaction time premature initiation rate0.20.30.6-0.7-0.80.60.6-0.60.6-0.6-0.6-0.50.5-0.50.6-0.50.50.80.40.60.80.40.4-0.6-0.4-0.80.5
Reaction time premature initiations0.40.71.1-1.0-1.00.80.9-0.90.9-0.8-0.8-0.80.8-0.80.8-0.80.81.10.80.81.00.70.7-0.9-0.6-0.90.7
Std. dev. reaction times0.61.22.0-0.9-0.91.11.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.11.10.90.81.00.91.11.2-1.1-1.2-1.01.4
Reaction time trials completed0.71.31.6-1.3-0.91.21.2-1.21.2-1.2-1.2-1.21.2-1.21.2-1.21.21.21.31.11.01.11.1-1.3-1.0-1.00.9
Reaction time trials AUC0.51.01.5-1.1-0.81.01.0-1.01.0-1.0-1.0-1.01.0-1.01.1-1.01.11.01.21.00.81.01.1-1.2-0.9-0.90.8
Run reversals in cocaine runway, females0.10.10.9-0.6-0.50.30.2-0.20.2-0.2-0.2-0.30.2-0.30.2-0.20.31.00.30.30.70.30.3-0.40.2-0.10.1
Run reversals in cocaine runway, males0.20.20.9-0.7-0.90.30.3-0.30.3-0.3-0.3-0.30.3-0.30.3-0.30.30.9-0.10.30.90.2-0.1-0.4-0.6-0.50.0
Latency to leave start box in cocaine runway0.80.93.81.01.3-0.9-1.11.0-1.11.00.90.8-0.80.8-0.90.8-0.7-0.9-0.2-1.2-0.6-0.3-0.00.40.41.9-1.4
Latency to leave start box in cocaine runway, F0.20.21.60.50.7-0.4-0.60.5-0.60.50.40.3-0.30.3-0.40.4-0.3-0.50.2-0.4-0.30.20.20.30.11.3-0.7
Latency to leave start box in cocaine runway, M0.40.41.60.40.7-0.6-0.70.6-0.70.60.60.5-0.50.5-0.60.5-0.5-0.3-0.2-1.00.1-0.40.1-0.40.21.2-1.3
Std. dev. time between licks in bursts0.10.10.6-0.6-0.40.20.2-0.20.2-0.2-0.2-0.20.2-0.20.2-0.20.20.8-0.10.10.80.1-0.0-0.10.0-0.4-0.1
Total sessions with >9 infusions0.60.72.9-0.9-1.00.81.0-0.91.0-0.9-0.8-0.80.8-0.80.8-0.80.70.90.31.10.80.10.3-0.7-0.4-1.71.1
Short access day 1 total inactive lever presses3.95.17.0-2.4-2.42.32.4-2.32.4-2.3-2.3-2.32.3-2.22.3-2.32.22.32.02.42.21.91.9-2.2-2.0-2.72.2
Short access day 10 total inactive lever presses0.00.00.20.00.1-0.00.0-0.00.00.00.00.0-0.00.1-0.00.0-0.1-0.1-0.3-0.2-0.4-0.1-0.2-0.10.1-0.30.3
Short access day 1 total infusions0.81.14.1-0.7-0.41.11.3-1.21.2-1.1-1.1-1.01.0-1.01.1-1.10.90.30.61.20.40.40.4-0.9-0.7-2.01.6
Short access day 10 total infusions0.50.62.3-0.7-0.70.80.9-0.90.9-0.8-0.8-0.70.7-0.70.8-0.80.70.50.40.90.60.20.3-0.6-0.5-1.51.1
Short access total infusions0.30.42.3-0.4-0.30.60.8-0.70.8-0.7-0.6-0.60.6-0.50.6-0.60.50.20.20.90.2-0.00.1-0.5-0.4-1.51.1
Short access day 1 locomotion0.10.10.60.20.30.10.2-0.10.2-0.1-0.0-0.00.00.00.1-0.0-0.0-0.4-0.40.4-0.3-0.5-0.40.10.2-0.70.4
Short access day 10 total locomotion0.40.82.31.21.4-0.8-0.70.7-0.70.80.80.8-0.80.8-0.70.8-0.8-1.5-1.0-0.6-1.5-0.9-0.80.90.70.5-0.1
Short access total locomotion0.40.41.10.70.7-0.6-0.40.5-0.50.50.60.6-0.60.6-0.60.6-0.7-0.8-1.0-0.1-0.8-1.0-0.90.80.8-0.2-0.1
One hour access (0.3 mA shock)0.00.10.30.30.4-0.2-0.10.1-0.10.10.10.1-0.10.1-0.20.1-0.2-0.5-0.10.2-0.6-0.3-0.20.2-0.1-0.10.2
Compulsive drug intake0.91.11.4-1.1-0.81.11.1-1.11.1-1.1-1.1-1.11.1-1.11.1-1.11.10.91.01.20.91.01.0-1.1-0.9-1.21.2
One hour access (shock baseline)0.10.10.30.50.4-0.4-0.40.4-0.40.40.40.4-0.40.4-0.40.3-0.4-0.5-0.2-0.1-0.6-0.4-0.30.40.00.3-0.2
Social response proportion2.52.93.6-1.9-1.81.81.8-1.81.8-1.8-1.7-1.71.7-1.71.8-1.71.71.81.21.71.71.51.4-1.6-1.4-1.91.4
Social responses1.92.42.7-1.4-1.31.61.7-1.61.7-1.6-1.6-1.61.6-1.61.7-1.61.61.31.01.51.31.61.5-1.6-1.5-1.61.6
Social time1.72.33.3-1.6-1.51.61.6-1.61.6-1.6-1.5-1.51.5-1.51.6-1.51.51.40.71.81.81.21.1-1.5-1.5-1.81.5
Soleus weight2.46.97.8-2.8-2.82.62.7-2.72.7-2.7-2.6-2.62.6-2.62.6-2.72.62.62.72.72.72.52.5-2.5-2.5-2.72.2
Bone: stiffness1.93.13.5-1.8-1.51.81.8-1.81.8-1.8-1.8-1.81.8-1.81.8-1.81.81.71.61.81.71.61.7-1.9-1.7-1.81.7
Tibialis anterior weight2.99.712.5-3.5-3.13.13.1-3.13.1-3.1-3.1-3.13.1-3.13.1-3.13.13.13.53.23.23.13.0-3.0-2.9-2.92.4
Time to tail flick, vehicle, before self-admin0.30.31.0-0.7-1.00.40.5-0.40.4-0.4-0.4-0.30.3-0.30.4-0.30.30.90.00.50.90.00.0-0.8-0.0-0.70.2
Time to tail flick, vehicle, after self-admin0.40.51.40.90.8-0.6-0.60.6-0.60.60.60.6-0.60.7-0.60.6-0.7-0.9-1.2-0.5-0.9-0.8-0.80.70.70.2-0.2
Time to tail flick, test, before self-admin0.00.00.2-0.3-0.40.00.0-0.00.0-0.0-0.0-0.00.0-0.10.0-0.00.10.40.0-0.10.40.10.1-0.2-0.20.2-0.4
Time to tail flick, test, after self-admin0.80.94.20.70.8-0.9-1.11.0-1.10.90.90.8-0.80.8-0.90.9-0.7-0.60.0-1.3-0.6-0.2-0.21.00.22.0-1.5
Delta time to tail flick, vehicle, before/after SA0.80.82.11.21.3-0.7-0.80.8-0.80.80.70.7-0.70.7-0.70.7-0.7-1.4-0.6-0.9-1.4-0.4-0.41.20.41.0-0.4
Delta time to tail flick, test, before/after SA0.60.71.41.01.2-0.8-0.80.8-0.80.80.80.7-0.70.7-0.80.8-0.7-1.1-0.5-0.8-1.1-0.6-0.60.80.60.9-0.5
Tibia length0.00.00.10.0-0.2-0.2-0.20.2-0.20.20.20.2-0.20.2-0.20.2-0.20.1-0.2-0.20.2-0.3-0.30.20.3-0.0-0.2
Ambulatory time before self-admin1.11.72.90.80.2-1.4-1.31.3-1.31.41.41.4-1.41.4-1.41.4-1.4-0.2-1.7-1.2-0.2-1.7-1.71.01.60.8-1.6
Ambulatory time after self-admin0.00.00.3-0.3-0.50.10.1-0.10.1-0.1-0.1-0.10.1-0.10.1-0.10.10.5-0.10.20.5-0.0-0.0-0.40.0-0.2-0.0
Bone: tissue strength1.51.52.41.10.5-1.3-1.21.3-1.21.31.31.3-1.31.3-1.31.3-1.3-0.8-1.5-1.3-0.8-1.4-1.41.31.40.9-1.3
Total heroin consumption2.73.15.7-1.5-1.71.81.6-1.71.6-1.7-1.8-1.81.8-1.91.7-1.81.81.32.21.51.32.42.4-1.8-2.1-0.81.5
Bone: trabecular number2.84.75.9-2.1-2.12.22.1-2.22.2-2.2-2.2-2.22.2-2.22.2-2.22.22.02.42.02.02.32.4-2.1-2.4-1.71.7
Bone: trabecular spacing0.20.30.50.40.2-0.6-0.50.6-0.50.60.60.6-0.60.6-0.60.6-0.6-0.3-0.7-0.4-0.2-0.7-0.70.50.60.4-0.6
Bone: trabecular thickness0.00.00.00.20.1-0.00.0-0.00.0-0.00.00.0-0.00.0-0.0-0.0-0.0-0.00.2-0.10.0-0.1-0.10.10.2-0.20.1
Bone: trabecular tissue density1.32.02.61.61.5-1.4-1.41.4-1.41.41.41.4-1.41.4-1.41.4-1.4-1.5-1.5-1.4-1.6-1.4-1.41.41.51.2-1.0
Water consumed over 24 hours0.00.10.20.30.4-0.2-0.20.2-0.20.20.20.2-0.20.2-0.20.2-0.2-0.30.0-0.4-0.3-0.1-0.20.40.30.3-0.2
Number of responses in last shaping day1.11.22.21.01.0-1.1-1.01.0-1.01.01.11.1-1.11.1-1.11.1-1.2-1.0-1.4-1.1-1.2-1.4-1.51.21.40.4-0.8