Hub : Genes

Hectd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Hectd1 0.07 0.06 6.9e-03 0.01 0.03 0.03 0.03 1.3e-01 2.3e-02 1.3e-02 2.9e-02
2 BLA isoform ratio NM_001419839.1 0.1 0.07 8.2e-05 0.06 0.04 0.03 0.03 4.5e-04 2.6e-03 1.0e-02 8.3e-03
3 BLA intron excision ratio chr6_69206174_69209504 0.07 0.06 2.1e-03 0.04 0.03 0.02 0.02 5.1e-03 1.3e-02 1.9e-02 4.0e-02
4 NAcc isoform ratio NM_001419839.1 0.02 0.02 5.1e-03 0.02 0.01 0 0.01 1.3e-03 2.3e-02 1.4e-01 1.0e-02
5 NAcc intron excision ratio chr6_69206033_69209504 0.04 0.03 5.2e-05 0.05 0.04 0.04 0.05 4.6e-06 1.7e-05 2.0e-05 3.5e-06
6 NAcc intron excision ratio chr6_69206174_69209504 0.04 0.03 3.8e-05 0.05 0.04 0.04 0.05 3.2e-06 1.1e-05 1.5e-05 2.1e-06
7 BLA intron excision ratio chr6_69206033_69209504 0.07 0.06 2.3e-03 0.01 0.02 0.02 0.01 8.5e-02 1.8e-02 2.7e-02 5.1e-02
8 Brain mRNA stability Hectd1 0.06 0.05 3.3e-04 0.02 0.03 0.02 0.03 4.3e-03 3.8e-04 4.1e-03 7.8e-04
9 BLA gene expression Hectd1 0.07 0.05 2.2e-03 0.04 0.04 0.05 0.05 4.9e-03 2.6e-03 1.7e-03 1.4e-03
10 Adipose gene expression Hectd1 0.13 0.09 1.9e-11 0.1 0.1 0.09 0.1 3.6e-11 2.5e-11 1.3e-10 4.3e-11
11 Brain gene expression Hectd1 0.04 0.03 2.1e-03 0.01 0.01 0 0 3.1e-02 3.9e-02 2.2e-01 1.3e-01
12 RMTg mRNA stability Hectd1 0.11 0.09 9.7e-03 0.09 0.09 0.12 0.08 2.5e-03 2.3e-03 3.2e-04 4.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.91.64.6-2.11.5-1.51.5-1.51.5-1.10.2-0.0-0.51.10.9
Area under the delay curve2.82.94.4-0.71.7-1.71.7-1.71.7-1.71.92.11.9-1.4-1.7
BMI with tail0.41.42.30.6-1.21.2-0.90.9-0.91.2-1.5-1.5-1.51.21.3
BMI without tail0.81.64.9-0.8-0.30.30.0-0.00.00.6-1.4-1.7-2.02.02.2
Body weight1.14.711.5-3.42.4-2.42.5-2.52.5-1.70.1-0.4-1.31.92.4
Weight adjusted by age0.50.60.80.7-0.90.9-0.80.8-0.80.8-0.7-0.8-0.50.30.8
Bone surface1.93.34.8-2.02.2-2.22.2-2.22.2-2.11.71.61.2-0.5-0.5
Bone volume1.73.05.5-2.32.2-2.22.1-2.12.1-1.91.31.10.60.1-0.1
Breakpoint value in progressive ratio session2.02.24.2-2.01.7-1.71.9-1.91.9-1.81.10.90.4-0.20.3
Number of licking bursts0.10.10.20.3-0.40.40.0-0.00.00.3-0.2-0.2-0.2-0.20.2
Context. condit. distance diff. score0.70.83.6-0.1-0.70.7-0.30.3-0.30.9-1.2-1.0-1.21.90.3
Locomotion velocity, session 10.20.30.6-0.40.5-0.50.6-0.60.6-0.50.50.50.5-0.8-0.2
Locomotion distance, session 11.01.33.01.7-1.51.5-1.31.3-1.31.4-0.9-0.7-0.3-0.1-0.2
Locomotion velocity, session 20.80.92.81.4-0.50.5-0.00.0-0.00.20.60.91.2-1.7-1.6
Locomotion distance, session 21.21.75.32.3-1.51.5-1.41.4-1.41.2-0.3-0.20.4-1.1-0.7
Locomotion velocity, session 30.70.83.01.7-0.90.9-0.60.6-0.60.8-0.00.40.7-0.6-1.4
Locomotion distance, session 31.21.32.11.5-1.31.3-0.90.9-0.91.4-1.3-1.1-1.01.10.6
Stereotopy head waving bouts, day 30.70.93.61.2-0.60.6-0.60.6-0.60.30.50.91.1-1.1-1.9
Stereotopy head waving duration, day 30.60.82.80.8-0.10.1-0.20.2-0.2-0.20.91.11.4-1.4-1.7
Locomotion velocity, session 75.56.18.51.9-2.62.6-2.32.3-2.32.9-2.9-2.8-2.62.41.6
Locomotion distance, session 73.74.77.91.1-2.12.1-1.51.5-1.52.3-2.7-2.8-2.72.22.4
Stereotopy head waving bouts, day 70.80.91.5-0.40.8-0.80.7-0.70.7-0.91.11.21.2-0.9-1.2
Stereotopy head waving duration, day 70.70.92.80.30.5-0.50.2-0.20.2-0.61.11.41.5-1.0-1.7
Locomotion velocity, session 80.10.10.40.00.3-0.3-0.10.1-0.1-0.20.50.60.6-0.3-0.6
Locomotion distance, session 80.40.61.01.0-1.01.0-0.70.7-0.71.0-0.8-0.6-0.50.9-0.4
Degree of sensitization distance0.10.10.4-0.60.1-0.10.3-0.30.3-0.1-0.2-0.4-0.50.30.5
Degree of sensitization stereotypy0.80.91.3-1.01.1-1.10.9-0.90.9-1.11.01.00.8-0.5-0.5
Conditioned locomotion0.40.52.40.9-0.30.30.1-0.10.10.00.60.81.0-0.9-1.5
Cocaine response after cond. corrected0.40.40.90.5-0.60.6-0.50.5-0.50.7-0.8-0.7-0.71.00.3
Cocaine response after cond. not corrected0.80.92.00.1-0.50.5-0.60.6-0.60.8-1.2-1.3-1.41.41.3
Cocaine response before conditioning0.50.63.0-0.4-0.10.1-0.50.5-0.50.3-0.7-1.1-1.00.61.7
Saline control response1.01.32.6-1.61.4-1.41.4-1.41.4-1.20.80.50.2-0.10.5
Bone: connectivity density1.82.87.6-2.81.8-1.82.0-2.02.0-1.40.2-0.1-0.81.71.5
Bone: cortical apparent density1.52.03.10.6-1.41.4-1.41.4-1.41.5-1.7-1.7-1.71.31.2
Bone: cortical area3.14.76.6-1.92.6-2.62.5-2.52.5-2.52.22.21.7-0.7-1.1
Bone: cortical porosity1.01.02.1-0.31.1-1.10.6-0.60.6-1.11.31.51.4-0.7-1.3
Bone: cortical porosity1.21.32.7-0.31.2-1.20.6-0.60.6-1.21.51.61.6-0.9-1.3
Bone: cortical thickness0.30.40.7-0.80.8-0.80.9-0.90.9-0.70.30.30.10.40.2
Bone: cortical thickness0.10.10.30.3-0.10.1-0.30.3-0.30.2-0.2-0.1-0.10.5-0.1
Bone: cortical tissue density1.52.03.10.6-1.41.4-1.41.4-1.41.5-1.7-1.8-1.71.31.1
Condit. Reinf. active minus inactive responses2.62.95.4-1.61.9-1.92.3-2.32.3-1.91.51.31.0-1.00.1
Condit. Reinf. active-inactive response ratio0.30.30.8-0.60.5-0.50.9-0.90.9-0.60.50.40.2-0.30.0
Condit. Reinf. active responses3.74.57.3-1.82.4-2.42.7-2.72.7-2.42.01.81.5-1.4-0.3
Condit. Reinf. inactive responses1.01.11.6-0.71.3-1.31.2-1.21.2-1.21.11.01.0-1.0-0.2
Incentive salience index mean3.54.37.0-1.52.3-2.32.6-2.62.6-2.32.11.81.6-1.5-0.3
Condit. Reinf. lever presses0.81.01.4-0.31.0-1.01.2-1.21.2-1.11.11.01.0-1.1-0.1
Condit. Reinf. active minus inactive responses0.00.00.10.2-0.20.2-0.00.0-0.00.2-0.1-0.10.0-0.20.1
Condit. Reinf. active-inactive response ratio0.10.10.30.5-0.30.3-0.30.3-0.30.20.10.20.3-0.4-0.5
Condit. Reinf. active responses0.00.00.10.3-0.20.2-0.00.0-0.00.2-0.0-0.10.1-0.40.1
Condit. Reinf. inactive responses0.10.10.8-0.2-0.10.1-0.00.0-0.00.2-0.4-0.6-0.50.20.9
Condit. Reinf. lever presses0.91.32.1-1.41.2-1.21.4-1.41.4-1.31.00.70.6-0.90.3
Condit. Reinf. lever reinforcers received0.50.71.1-0.60.8-0.81.0-1.01.0-0.80.90.80.8-0.8-0.3
Conditioned reinforcement - actives2.92.93.8-0.91.9-1.91.8-1.81.8-1.81.91.91.8-1.5-1.2
Conditioned reinforcement - inactives1.11.22.1-1.41.4-1.41.4-1.41.4-1.20.90.70.5-0.2-0.1
Conditioned locomotion0.20.30.60.00.5-0.50.4-0.40.4-0.50.70.60.7-0.6-0.4
Patch foraging indifference point 0 sec2.94.76.5-1.92.5-2.52.5-2.52.5-2.62.32.11.8-1.5-0.6
Patch foraging indifference point AUC2.63.04.6-0.71.9-1.91.6-1.61.6-1.92.12.22.1-1.2-1.8
Delay disc. indifference point, 0s delay1.31.41.8-1.11.2-1.21.4-1.41.4-1.21.21.31.0-0.6-1.1
Delay disc. indifference point, 16s delay2.02.03.5-0.31.2-1.21.2-1.21.2-1.41.71.91.8-1.6-1.6
Delay disc. indifference point, 2s delay0.80.91.4-0.71.1-1.11.2-1.21.2-1.00.90.90.8-0.4-0.5
Delay disc. indifference point, 24s delay4.94.86.5-1.22.3-2.32.3-2.32.3-2.32.52.62.3-2.1-1.7
Delay disc. indifference point, 4s delay0.20.21.10.7-0.00.00.0-0.00.00.10.30.60.6-0.2-1.1
Delay disc. indifference point, 8s delay0.70.81.1-0.51.0-1.01.0-1.01.0-0.90.90.90.7-0.4-0.5
Indifference point function ln k0.30.51.2-0.0-0.60.6-0.30.3-0.30.6-0.8-1.0-1.00.51.1
Indifference point function log k0.30.51.2-0.0-0.60.6-0.30.3-0.30.6-0.8-1.0-1.00.51.1
Patch foraging total patch changes 0 sec3.35.37.3-1.92.6-2.62.6-2.62.6-2.72.52.21.9-1.7-0.8
Patch foraging total patch changes 12 sec3.54.66.6-1.52.6-2.62.2-2.22.2-2.62.42.32.0-1.6-0.8
Patch foraging total patch changes 18 sec0.81.01.5-0.41.2-1.21.0-1.01.0-1.21.21.11.0-0.9-0.2
Patch foraging total patch changes 24 sec1.31.62.3-0.61.5-1.51.2-1.21.2-1.51.51.41.3-1.4-0.4
Patch foraging total patch changes 6 sec3.04.56.4-1.82.5-2.52.5-2.52.5-2.52.22.01.7-1.1-0.7
Patch foraging time to switch 0 sec13.220.427.42.6-4.74.7-4.64.6-4.65.0-5.2-5.1-4.93.93.6
Patch foraging water rate 0 sec3.96.29.0-1.22.5-2.52.4-2.42.4-2.83.03.02.9-2.4-2.1
Patch foraging water rate 12 sec0.91.43.1-1.81.5-1.51.5-1.51.5-1.40.80.50.3-0.00.4
Patch foraging water rate 18 sec1.62.23.0-1.51.6-1.61.7-1.71.7-1.71.61.51.2-0.9-0.7
Patch foraging water rate 24 sec1.21.73.1-1.11.3-1.31.7-1.71.7-1.41.21.30.9-0.1-0.9
Patch foraging water rate 6 sec5.07.29.3-1.93.1-3.12.9-2.92.9-3.03.02.92.6-2.0-1.7
Seeking ratio, delayed vs. immediate footshock0.50.63.11.8-0.90.9-0.80.8-0.80.7-0.2-0.20.3-0.2-0.2
Distance traveled before self-admin0.00.00.10.30.2-0.20.2-0.20.2-0.20.20.30.3-0.2-0.1
Distance traveled after self-admin0.20.20.40.5-0.50.5-0.60.6-0.60.5-0.4-0.3-0.2-0.0-0.1
Extensor digitorum longus weight1.35.216.3-4.02.4-2.42.3-2.32.3-1.80.0-0.7-1.52.02.9
Bone: elastic displacement0.91.02.4-0.3-0.50.5-0.30.3-0.30.8-1.3-1.4-1.61.31.6
Bone: elastic work1.21.55.4-0.6-0.10.10.0-0.00.00.6-1.4-1.6-1.91.92.3
Bone: endosteal estimation2.55.59.3-0.81.9-1.92.0-2.02.0-2.32.83.13.0-2.4-2.9
Bone: endosteal perimeter4.08.213.0-1.32.8-2.82.7-2.72.7-3.03.43.63.4-2.6-2.8
Epididymis fat weight0.30.81.10.5-1.01.0-0.90.9-0.90.9-1.0-0.9-1.00.80.5
Delta time in closed arm before/after self-admin0.60.61.1-0.71.1-1.10.8-0.80.8-0.90.70.70.5-0.2-0.4
Delta time in open arm before/after self-admin0.10.10.5-0.7-0.10.10.1-0.10.1-0.0-0.2-0.3-0.40.40.3
Diff in mean of infusions in LGA sessions0.40.41.00.9-0.70.7-0.50.5-0.50.30.20.40.5-0.9-1.0
Delay discount exponential model param2.12.23.50.5-1.41.4-1.51.5-1.51.5-1.7-1.9-1.71.31.6
Extinction: sum of active levers before priming1.41.43.8-1.61.1-1.11.1-1.11.1-0.7-0.3-0.7-1.11.62.0
Active lever presses in extinction session 62.01.94.6-2.11.6-1.61.6-1.61.6-1.30.3-0.0-0.60.91.4
Bone: final force0.00.00.50.00.1-0.10.1-0.10.10.0-0.10.1-0.00.7-0.2
Bone: final moment0.10.10.4-0.10.2-0.20.2-0.20.2-0.10.10.30.20.6-0.5
Food consumed during 24 hour testing period1.01.32.0-1.01.3-1.31.4-1.41.4-1.31.10.90.8-0.7-0.1
Glucose1.11.63.8-1.91.4-1.41.7-1.71.7-1.30.50.3-0.20.40.7
Heart weight1.01.42.7-1.71.5-1.51.4-1.41.4-1.41.00.80.4-0.60.2
Delay discount hyperbolic model param1.92.03.10.5-1.41.4-1.41.4-1.41.4-1.6-1.7-1.61.21.5
Intermittent access intake day 1-15 change0.40.41.1-1.10.8-0.80.3-0.30.3-0.3-0.3-0.5-0.71.01.0
Intermittent access intake escalation0.60.61.6-1.10.8-0.80.4-0.40.4-0.4-0.3-0.5-0.81.11.3
Intermittent access intake escalation 21.11.13.6-0.80.3-0.3-0.00.0-0.00.2-1.0-1.3-1.61.81.9
Intermitt. access day 1 inactive lever presses2.32.53.4-0.61.7-1.71.6-1.61.6-1.71.81.81.8-1.4-1.3
Intermitt. access day 15 inactive lever presses3.13.44.4-1.41.9-1.91.7-1.71.7-1.92.12.11.9-1.8-1.8
Intermitt. access escalation Index0.50.41.3-0.5-0.10.10.2-0.20.20.2-0.7-0.9-1.01.11.1
Intermittent access day 1 total infusions1.01.11.7-0.61.2-1.21.3-1.31.3-1.21.11.01.0-0.6-0.3
Intermittent access day 15 total infusions0.91.02.0-1.21.4-1.41.2-1.21.2-1.10.50.2-0.00.50.8
Intermittent access terminal intake (last 3 days)0.80.81.8-1.01.3-1.31.1-1.11.1-1.00.60.40.10.20.5
Intermittent access total infusions0.40.50.9-0.70.9-0.90.8-0.80.8-0.60.2-0.0-0.10.50.8
Intermittent access day 1 locomotion1.61.72.2-0.61.5-1.51.5-1.51.5-1.41.51.31.4-1.0-0.6
Intermittent access day 15 total locomotion0.50.61.0-1.00.8-0.81.0-1.01.0-0.70.2-0.0-0.20.60.8
Intermittent access total locomotion0.40.40.8-0.60.8-0.80.8-0.80.8-0.50.1-0.1-0.20.60.9
Intermittent access standard deviation0.60.61.8-1.01.3-1.30.7-0.70.7-0.90.50.50.20.20.1
Left kidney weight0.30.92.5-1.30.4-0.40.2-0.20.20.0-0.8-1.0-1.31.51.6
Right kidney weight0.41.13.3-1.20.2-0.2-0.10.1-0.10.3-1.1-1.3-1.61.71.8
Cocaine induced anxiety0.80.91.5-0.40.7-0.70.8-0.80.8-0.91.21.21.2-1.2-1.1
Post-drug Anxiety0.70.81.5-0.50.7-0.70.6-0.60.6-0.81.11.21.1-1.2-1.2
Baseline Anxiety1.31.31.90.9-1.31.3-1.41.4-1.41.3-1.2-1.1-1.00.70.4
Tail length0.61.83.5-1.91.7-1.71.6-1.61.6-1.30.40.0-0.40.91.3
Length with tail2.28.116.6-4.13.7-3.73.6-3.63.6-2.91.40.8-0.11.01.7
Length without tail1.63.56.2-2.52.5-2.52.4-2.42.4-2.01.00.70.10.50.9
Times rat made contact with spout0.91.01.40.7-1.11.1-0.90.9-0.91.1-1.2-1.1-1.01.00.8
Lifetime Intake0.30.40.6-0.60.8-0.80.8-0.80.8-0.60.2-0.0-0.10.40.7
Liver weight, left0.20.40.8-0.70.5-0.50.8-0.80.8-0.3-0.0-0.0-0.30.90.2
Liver weight, right0.20.31.5-0.40.2-0.20.4-0.40.40.1-0.4-0.5-0.71.20.8
Locomotor activity5.58.815.7-4.03.7-3.73.8-3.83.8-3.42.21.60.9-0.10.6
Locomotor testing distance3.45.613.5-3.73.0-3.02.9-2.92.9-2.61.30.60.00.61.5
Locomotor testing rearing2.13.28.1-2.81.8-1.81.7-1.71.7-1.3-0.1-0.8-1.31.72.8
Locomotion in novel chamber2.32.93.91.9-1.91.9-2.02.0-2.02.0-1.6-1.5-1.11.20.5
Locomotion in novel chamber post-restriction0.70.93.01.10.0-0.00.1-0.10.1-0.30.91.21.4-1.7-1.4
Fecal boli incidents, locomotor time 10.70.82.6-1.60.9-0.90.6-0.60.6-0.6-0.2-0.4-0.90.91.5
Change in fecal boli incidents, locomotor task0.10.10.4-0.1-0.30.30.0-0.00.00.2-0.3-0.4-0.40.70.3
Time >=10cm from walls, locomotor time 10.70.71.3-0.81.0-1.01.2-1.21.2-0.90.70.60.5-0.1-0.3
Bouts of movement, locomotor time 12.22.43.2-1.31.6-1.61.5-1.51.5-1.71.81.81.6-1.4-1.2
Total resting periods, locomotor time 12.52.73.6-1.31.7-1.71.6-1.61.6-1.81.91.91.7-1.6-1.3
Rest time, locomotor task time 14.14.56.9-1.21.9-1.91.9-1.91.9-2.22.52.62.4-2.6-2.1
Distance moved, locomotor task time 11.51.73.10.5-1.21.2-1.11.1-1.11.3-1.5-1.6-1.51.81.2
Vertical activity count, locomotor time 11.51.53.20.1-1.01.0-0.80.8-0.81.1-1.5-1.7-1.71.81.6
Time >=10cm from walls, locomotor time 20.91.01.8-1.21.3-1.31.4-1.41.4-1.00.50.30.00.40.4
Bouts of movement, locomotor time 20.30.30.70.10.4-0.40.4-0.40.4-0.50.70.70.8-0.8-0.6
Total resting periods, locomotor time 20.10.10.40.20.1-0.10.0-0.00.0-0.20.50.40.6-0.7-0.5
Rest time, locomotor task time 20.00.00.1-0.30.1-0.1-0.00.0-0.0-0.10.10.10.1-0.30.0
Distance moved, locomotor task time 20.20.20.3-0.30.3-0.30.6-0.60.6-0.50.40.50.3-0.0-0.5
Vertical activity count, locomotor time 20.00.00.10.2-0.30.3-0.00.0-0.00.2-0.00.10.1-0.2-0.3
Light reinforcement 10.30.53.0-0.80.3-0.30.2-0.20.2-0.0-0.6-0.8-1.00.71.7
Light reinforcement 20.71.03.91.00.3-0.30.0-0.00.0-0.51.11.21.5-2.0-1.1
Bone: marrow area2.65.79.6-0.82.0-2.02.1-2.12.1-2.42.93.13.0-2.4-2.9
Bone: maximum diameter6.111.216.3-1.83.3-3.33.4-3.43.4-3.63.94.03.7-2.9-2.9
Bone: maximum force0.30.61.0-0.40.8-0.80.7-0.70.7-0.80.81.00.80.0-0.9
Bone: maximum moment0.40.71.2-0.40.9-0.90.7-0.70.7-0.90.91.10.90.0-1.1
Mean time between licks in bursts0.10.10.5-0.70.1-0.1-0.10.1-0.1-0.10.10.20.00.1-0.6
Mean num. licks in bursts0.10.10.7-0.30.0-0.0-0.30.3-0.30.1-0.4-0.4-0.50.90.4
Cd content in liver0.40.52.2-0.90.3-0.30.2-0.20.2-0.1-0.5-0.6-0.91.50.9
Co content in liver0.30.40.9-0.80.3-0.30.6-0.60.6-0.1-0.3-0.4-0.71.00.9
Cu content in liver0.70.91.20.9-1.01.0-0.90.9-0.91.1-1.0-1.0-0.80.90.6
Fe content in liver0.60.71.30.5-0.80.8-1.11.1-1.10.8-0.8-0.8-0.70.30.6
K content in liver3.13.110.93.3-1.81.8-2.02.0-2.01.6-0.30.20.9-1.2-1.8
Mg content in liver4.14.211.03.3-2.42.4-2.62.6-2.62.2-1.1-0.60.1-0.4-1.2
Mn content in liver2.22.59.31.50.1-0.1-0.10.1-0.1-0.51.62.12.5-2.3-3.0
Na content in liver2.42.54.42.0-1.81.8-2.12.1-2.11.7-1.3-1.2-0.80.40.4
Rb content in liver1.72.15.12.3-1.71.7-1.81.8-1.81.5-0.6-0.30.2-0.6-1.2
Se content in liver4.75.710.13.2-2.82.8-3.23.2-3.22.6-1.7-1.5-0.80.10.0
Sr content in liver0.20.20.6-0.50.0-0.0-0.10.1-0.10.1-0.5-0.6-0.80.80.7
Zn content in liver0.20.21.21.1-0.30.3-0.40.4-0.40.4-0.2-0.10.10.00.0
Bone: minimum diameter1.93.54.8-1.42.2-2.21.9-1.91.9-2.22.12.21.8-0.8-1.5
Time in familiar zone, hab. session 10.80.71.7-0.2-0.30.3-0.70.7-0.70.5-0.9-1.0-1.21.31.2
Time in novel zone, hab. session 10.90.91.5-0.60.6-0.61.0-1.01.0-0.81.01.11.0-1.0-1.2
Total zone transitions, hab. session 10.91.34.12.0-0.90.9-0.90.9-0.90.70.30.61.1-1.6-1.5
Total locomotion distance, hab. session 11.92.76.02.4-2.02.0-2.12.1-2.11.8-1.0-0.8-0.2-0.5-0.3
Locomotion velocity, hab. session 11.42.06.62.6-1.61.6-1.71.7-1.71.3-0.3-0.10.5-1.2-0.7
Time in familiar zone, hab. session 21.92.03.00.2-1.11.1-1.51.5-1.51.2-1.6-1.7-1.71.41.5
Time in novel zone, hab. session 23.33.34.3-1.01.8-1.82.0-2.02.0-1.92.12.11.9-1.7-1.3
Total zone transitions, hab. session 21.62.06.32.3-0.80.8-0.60.6-0.60.40.91.21.8-2.5-2.2
Total locomotion distance, hab. session 21.21.65.12.0-0.90.9-0.90.9-0.90.50.60.81.4-2.2-1.5
Locomotion velocity, hab. session 21.41.95.32.3-1.01.0-1.01.0-1.00.60.70.91.6-2.3-1.8
Novel to familiar place preference ratio1.01.11.4-0.41.0-1.01.1-1.11.1-1.11.21.21.1-0.9-0.8
Novelty place preference2.52.53.1-0.91.7-1.71.8-1.81.8-1.71.81.71.6-1.3-1.1
Time in novel zone, NPP test2.12.22.8-1.01.6-1.61.7-1.71.7-1.61.61.51.3-1.1-0.9
Total zone transitions, NPP test0.50.72.31.5-0.60.6-0.40.4-0.40.30.40.61.0-1.4-1.1
Total locomotion distance, NPP test0.60.82.91.7-0.80.8-0.50.5-0.50.50.40.51.0-1.5-1.1
Locomotion velocity, NPP test0.50.72.91.7-0.80.8-0.60.6-0.60.60.20.30.8-1.2-0.8
Intraocular pressure0.50.61.9-1.40.6-0.60.8-0.80.8-0.3-0.3-0.6-0.91.01.0
Delta distance traveled before/after self-admin0.20.30.50.5-0.60.6-0.70.7-0.70.5-0.3-0.1-0.1-0.4-0.3
Delta ambulatory time before/after self-admin0.40.40.70.6-0.80.8-0.80.8-0.80.7-0.4-0.2-0.1-0.4-0.4
Parametrial fat weight1.02.06.4-0.9-0.10.1-0.40.4-0.40.6-1.6-1.8-2.12.52.2
Pavlov. Cond. lever latency0.60.72.9-0.4-0.50.5-0.50.5-0.50.7-1.1-1.0-1.21.70.5
Pavlov. Cond. magazine entry latency1.01.34.32.1-1.41.4-1.31.3-1.31.1-0.4-0.40.1-1.1-0.1
Pavlov. Cond. change in total contacts0.60.63.90.40.1-0.10.3-0.30.3-0.40.90.81.1-2.0-0.6
Pavlov. Cond. index score0.50.72.91.6-0.70.7-0.50.5-0.50.30.30.30.8-1.7-0.4
Pavlov. Cond. latency score0.50.63.21.4-0.50.5-0.30.3-0.30.10.50.50.9-1.8-0.5
Pavlov. Cond. lever contacts0.20.21.30.40.2-0.20.2-0.20.2-0.30.50.30.5-1.20.3
Pavlov. Cond. magazine entry number1.01.34.2-2.11.2-1.21.2-1.21.2-0.80.0-0.0-0.61.70.6
Pavlov. Cond. intertrial magazine entries0.60.82.0-1.30.4-0.40.8-0.80.8-0.1-0.6-0.8-1.11.21.4
Pavlov. Cond. lever-magazine prob. diff.0.50.72.51.6-0.80.8-0.60.6-0.60.40.20.20.6-1.5-0.3
Pavlov. Cond. response bias0.60.72.41.5-0.80.8-0.70.7-0.70.40.20.20.6-1.5-0.3
Pavlov. Cond. lever latency2.22.94.12.0-1.81.8-2.02.0-2.02.0-1.7-1.4-1.21.20.5
Pavlov. Cond. magazine entry latency0.10.10.50.2-0.20.2-0.20.2-0.20.10.0-0.10.1-0.70.3
Pavlov. Cond. change in total contacts2.43.35.3-2.32.1-2.12.2-2.22.2-2.11.71.31.0-1.10.1
Pavlov. Cond. index score1.52.02.8-1.61.5-1.51.7-1.71.7-1.61.41.00.9-1.30.1
Pavlov. Cond. latency score1.51.92.6-1.41.5-1.51.6-1.61.6-1.61.41.11.0-1.4-0.0
Pavlov. Cond. lever contacts1.31.73.0-1.71.4-1.41.6-1.61.6-1.51.31.00.8-1.0-0.1
Pavlov. Cond. magazine entry number1.01.21.60.9-1.01.0-1.31.3-1.31.2-1.2-1.0-1.01.20.4
Pavlov. Cond. intertrial magazine entries0.10.20.50.5-0.50.5-0.30.3-0.30.5-0.3-0.1-0.00.3-0.7
Pavlov. Cond. lever-magazine prob. diff.1.62.12.9-1.71.5-1.51.7-1.71.7-1.71.41.00.9-1.40.1
Pavlov. Cond. response bias0.91.32.3-1.51.2-1.21.3-1.31.3-1.31.00.80.7-0.90.0
Time in closed arm before self-admin1.82.04.62.1-1.91.9-1.61.6-1.61.6-1.1-1.0-0.60.30.5
Time in closed arm after self-admin0.60.62.31.5-0.90.9-0.90.9-0.90.8-0.3-0.10.1-0.3-0.3
Time in open arm before self-admin0.80.81.5-0.10.8-0.80.7-0.70.7-0.81.01.21.1-1.1-1.2
Time in open arm after self-admin0.30.31.20.20.1-0.10.1-0.10.1-0.20.60.70.8-0.9-1.1
Bone: periosteal estimation4.08.312.7-1.52.8-2.82.8-2.82.8-3.13.43.63.3-2.3-2.9
Bone: periosteal perimeter3.35.67.9-1.32.5-2.52.4-2.42.4-2.62.72.82.5-1.6-2.0
Bone: post-yield work0.81.12.0-0.61.1-1.10.6-0.60.6-1.11.31.41.4-0.7-1.4
Progressive ratio test 1 active lever presses0.91.01.5-0.91.2-1.21.2-1.21.2-1.11.00.80.7-0.4-0.3
Progressive ratio test 1 breakpoint1.11.11.4-0.71.2-1.21.2-1.21.2-1.21.21.11.0-0.7-0.6
Progressive ratio test 1 inactive lever presses2.72.94.1-1.22.0-2.02.0-2.02.0-1.91.81.61.5-1.1-0.7
Progressive ratio test 2 active lever presses0.10.10.60.8-0.30.3-0.30.3-0.30.3-0.2-0.20.00.00.1
Progressive ratio test 2 breakpoint0.20.20.80.9-0.40.4-0.50.5-0.50.5-0.3-0.3-0.10.10.2
Progressive ratio test 2 inactive lever presses1.01.21.8-0.81.3-1.31.3-1.31.3-1.21.11.00.9-0.7-0.4
Incentive Sensitization - Responses3.83.96.32.5-2.22.2-2.32.3-2.32.3-1.8-1.7-1.20.80.9
Incentive Sensitization - Breakpoint3.53.65.62.4-2.12.1-2.22.2-2.22.2-1.8-1.7-1.20.90.9
Sum of active levers in priming session hrs 5-60.70.71.6-1.31.1-1.11.0-1.01.0-0.80.30.2-0.20.20.5
Progressive ratio0.50.62.50.7-0.60.6-0.60.6-0.60.40.30.60.8-1.1-1.6
Food seeking constrained by brief footshock0.20.30.90.10.1-0.10.4-0.40.4-0.20.60.60.8-0.6-0.9
Seeking ratio, punishment vs. effort0.20.30.7-0.60.5-0.50.7-0.70.7-0.4-0.0-0.2-0.30.50.8
Retroperitoneal fat weight1.65.111.0-0.1-1.31.3-1.61.6-1.61.9-2.8-2.9-3.23.32.9
Reaction time number correct0.40.51.30.0-0.40.4-0.50.5-0.50.5-0.9-0.8-1.11.20.9
Reaction time mean minus median3.24.212.43.5-2.42.4-2.42.4-2.42.2-0.8-0.40.5-1.0-1.5
Reaction time mean minus median AUC2.43.18.52.9-2.02.0-2.22.2-2.21.9-0.7-0.30.4-0.9-1.2
Reaction time num false alarms0.50.61.4-0.50.5-0.50.8-0.80.8-0.80.91.00.9-1.2-0.7
Reaction time num false alarms AUC0.40.51.0-0.40.4-0.40.6-0.60.6-0.70.91.00.9-1.0-0.9
Reaction time trials correct on left0.40.51.30.0-0.40.4-0.50.5-0.50.5-0.9-0.8-1.11.20.9
Reaction time trials on left0.30.41.00.1-0.40.4-0.50.5-0.50.5-0.8-0.8-1.01.00.8
Reaction time mean1.52.13.41.6-1.81.8-1.91.9-1.91.6-1.2-1.1-0.70.10.1
Reaction time mean AUC1.82.53.91.7-1.91.9-2.02.0-2.01.8-1.4-1.3-0.90.30.3
Median of all reaction times1.11.52.30.7-1.41.4-1.51.5-1.51.3-1.3-1.2-1.10.60.7
Reaction time omissions1.41.94.82.2-1.31.3-1.21.2-1.20.90.30.61.2-1.7-2.0
Reaction time false alarm rate0.91.22.2-0.70.8-0.81.0-1.01.0-1.11.31.31.3-1.5-1.1
Reaction time premature initiation rate0.91.21.9-0.81.4-1.41.3-1.31.3-1.21.10.90.9-0.4-0.4
Reaction time premature initiations0.40.51.1-0.71.1-1.10.9-0.90.9-0.80.50.40.30.30.1
Std. dev. reaction times2.23.17.92.8-2.12.1-2.12.1-2.11.9-0.7-0.40.3-0.9-1.3
Reaction time trials completed0.30.41.00.1-0.40.4-0.50.5-0.50.5-0.8-0.8-1.01.00.8
Reaction time trials AUC0.30.51.2-0.1-0.40.4-0.50.5-0.50.4-0.8-0.8-1.11.11.0
Run reversals in cocaine runway, females0.70.72.30.6-0.20.2-0.30.3-0.3-0.10.70.91.2-1.5-1.4
Run reversals in cocaine runway, males0.10.10.40.4-0.20.2-0.00.0-0.00.2-0.3-0.3-0.30.70.2
Latency to leave start box in cocaine runway0.20.20.30.5-0.60.6-0.60.6-0.60.5-0.3-0.3-0.2-0.20.0
Latency to leave start box in cocaine runway, F0.30.30.60.6-0.80.8-0.70.7-0.70.6-0.4-0.3-0.2-0.1-0.2
Latency to leave start box in cocaine runway, M0.00.00.20.00.1-0.10.1-0.10.1-0.10.20.10.1-0.40.1
Std. dev. time between licks in bursts0.50.61.20.6-0.90.9-1.11.1-1.10.7-0.6-0.6-0.50.20.4
Total sessions with >9 infusions1.61.83.0-1.61.6-1.61.7-1.71.7-1.41.00.90.6-0.3-0.1
Short access day 1 total inactive lever presses3.23.67.6-2.82.3-2.32.4-2.42.4-1.90.80.3-0.20.81.3
Short access day 10 total inactive lever presses1.51.72.8-0.41.1-1.11.1-1.11.1-1.31.61.71.6-1.5-1.3
Short access day 1 total infusions1.51.63.0-1.71.6-1.61.7-1.71.7-1.30.60.3-0.00.40.7
Short access day 10 total infusions0.50.61.2-0.41.1-1.10.8-0.80.8-0.90.80.70.7-0.4-0.2
Short access total infusions0.20.20.4-0.40.5-0.50.6-0.60.6-0.30.0-0.1-0.20.40.6
Short access day 1 locomotion0.70.71.3-1.01.1-1.11.2-1.21.2-0.80.40.10.00.20.5
Short access day 10 total locomotion0.30.30.8-0.50.9-0.90.5-0.50.5-0.60.30.30.10.30.3
Short access total locomotion0.80.91.8-0.91.4-1.41.2-1.21.2-1.00.70.50.40.10.3
One hour access (0.3 mA shock)1.72.03.8-1.72.0-2.01.7-1.71.7-1.50.90.50.20.40.6
Compulsive drug intake0.60.61.2-0.10.1-0.10.8-0.80.8-0.50.80.90.9-1.1-1.1
One hour access (shock baseline)0.50.61.7-0.81.0-1.00.4-0.40.4-0.4-0.2-0.5-0.71.11.3
Social response proportion0.50.61.1-0.70.8-0.81.0-1.01.0-0.70.50.70.40.0-0.7
Social responses0.81.11.5-1.11.2-1.21.2-1.21.2-1.11.01.00.8-0.6-0.5
Social time1.21.64.8-2.21.7-1.71.4-1.41.4-1.30.60.4-0.10.40.5
Soleus weight1.23.55.4-1.92.3-2.32.0-2.02.0-2.21.91.81.5-0.8-0.6
Bone: stiffness0.50.73.10.50.2-0.20.2-0.20.2-0.41.01.31.4-0.6-1.8
Tibialis anterior weight1.65.615.9-4.02.6-2.62.6-2.62.6-2.00.3-0.3-1.22.12.5
Time to tail flick, vehicle, before self-admin0.10.10.30.20.0-0.00.0-0.00.0-0.20.40.50.6-0.4-0.5
Time to tail flick, vehicle, after self-admin0.70.71.60.00.6-0.60.6-0.60.6-0.81.11.11.2-1.2-0.9
Time to tail flick, test, before self-admin0.20.20.7-0.1-0.00.0-0.20.2-0.20.2-0.5-0.5-0.60.60.8
Time to tail flick, test, after self-admin1.01.03.8-2.01.2-1.21.1-1.11.1-1.00.40.3-0.10.20.1
Delta time to tail flick, vehicle, before/after SA0.40.40.8-0.30.5-0.50.5-0.50.5-0.60.70.70.8-0.9-0.8
Delta time to tail flick, test, before/after SA0.10.10.4-0.50.1-0.10.1-0.10.1-0.10.20.20.2-0.2-0.6
Tibia length1.74.96.7-1.82.5-2.52.6-2.62.6-2.52.32.11.8-1.7-1.0
Ambulatory time before self-admin0.00.00.10.30.1-0.10.1-0.10.1-0.10.10.10.1-0.00.0
Ambulatory time after self-admin0.50.50.70.6-0.80.8-0.80.8-0.80.8-0.8-0.7-0.70.40.4
Bone: tissue strength0.50.40.70.4-0.80.8-0.50.5-0.50.8-0.8-0.8-0.70.60.6
Total heroin consumption1.31.63.4-1.91.4-1.41.6-1.61.6-1.40.90.80.3-0.1-0.0
Bone: trabecular number1.01.64.2-2.01.2-1.21.1-1.11.1-0.6-0.4-0.7-1.32.01.5
Bone: trabecular spacing3.64.78.22.9-2.72.7-2.62.6-2.62.5-1.8-1.6-1.00.30.3
Bone: trabecular thickness0.91.13.1-1.81.3-1.31.3-1.31.3-1.10.50.4-0.10.30.3
Bone: trabecular tissue density0.81.22.51.6-0.70.7-1.21.2-1.20.50.40.71.1-1.5-1.4
Water consumed over 24 hours0.30.41.0-0.90.3-0.30.4-0.40.4-0.2-0.3-0.5-0.71.01.0
Number of responses in last shaping day0.20.20.5-0.10.7-0.70.1-0.10.1-0.50.50.60.5-0.4-0.4