Hub : Genes

Gng7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Gng7 0.03 0.03 2.2e-03 0.01 0.01 0.01 0.01 1.3e-02 1.9e-02 4.3e-02 2.5e-02
2 IL mRNA stability Gng7 0.3 0.17 2.5e-05 0.08 0.1 0.1 0.09 5.2e-03 2.5e-03 2.0e-03 4.3e-03
3 NAcc isoform ratio XM_039079813.1 0.02 0.01 2.6e-03 0.02 0.02 0.02 0.02 4.4e-03 2.1e-03 4.7e-03 3.8e-03
4 BLA mRNA stability Gng7 0.05 0.04 8.0e-03 0.03 0.02 0.01 0.02 1.0e-02 2.3e-02 1.1e-01 3.4e-02
5 NAcc isoform ratio XM_017595070.2 0.02 0.01 8.0e-03 0.02 0.01 0.01 0.01 2.1e-03 1.8e-02 4.1e-02 1.1e-02
6 OFC gene expression Gng7 0.44 0.18 1.3e-11 0.36 0.34 0.4 0.38 1.7e-09 6.1e-09 1.9e-10 3.9e-10
7 IL gene expression Gng7 0.12 0.1 8.8e-03 0.03 0.03 0.02 0.02 5.8e-02 5.9e-02 1.1e-01 1.2e-01
8 PL mRNA stability Gng7 0.06 0.04 2.2e-08 0.08 0.07 0.07 0.07 2.8e-09 4.9e-08 3.3e-08 3.0e-08
9 Eye isoform ratio XM_017595070.2 0.18 0.14 5.0e-03 0.12 0.09 0.09 0.08 6.0e-03 1.7e-02 1.8e-02 2.3e-02
10 PL gene expression Gng7 0.04 0.03 5.9e-04 0.02 0.01 0.01 0.01 2.1e-03 2.0e-02 1.5e-02 2.4e-02
11 OFC mRNA stability Gng7 0.33 0.17 1.8e-08 0.28 0.28 0.28 0.28 1.7e-07 3.1e-07 2.8e-07 3.1e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.30.40.90.9-0.00.5-0.60.6-0.6-0.8-0.8-0.7-0.7-0.6
Area under the delay curve2.52.73.3-1.7-1.61.7-1.71.8-1.6-1.6-1.6-1.6-1.6-1.4
BMI with tail6.520.923.7-4.9-4.74.6-4.54.5-4.5-4.5-4.5-4.5-4.5-4.5
BMI without tail2.14.38.8-3.0-2.22.0-1.92.0-2.0-1.9-1.9-1.9-1.9-1.9
Body weight1.14.75.5-2.3-2.32.2-2.22.2-2.1-2.1-2.1-2.1-2.1-2.2
Weight adjusted by age0.20.21.1-1.0-0.50.4-0.40.2-0.3-0.3-0.3-0.3-0.3-0.4
Bone surface0.20.43.11.80.50.1-0.30.3-0.3-0.5-0.5-0.4-0.4-0.3
Bone volume0.30.43.31.80.50.1-0.30.3-0.3-0.5-0.5-0.4-0.4-0.3
Breakpoint value in progressive ratio session6.06.68.31.82.6-2.72.9-2.72.72.62.62.62.52.5
Number of licking bursts0.10.10.7-0.8-0.2-0.10.2-0.20.10.10.20.10.10.2
Context. condit. distance diff. score0.30.30.4-0.6-0.60.6-0.50.6-0.6-0.6-0.6-0.6-0.6-0.6
Locomotion velocity, session 10.40.52.11.40.8-0.60.5-0.40.50.50.50.50.60.5
Locomotion distance, session 10.20.22.11.40.20.0-0.10.2-0.1-0.1-0.2-0.2-0.1-0.2
Locomotion velocity, session 22.93.48.93.02.0-1.71.6-1.51.61.61.61.61.81.6
Locomotion distance, session 21.11.56.22.51.3-1.11.0-0.90.91.01.01.01.11.0
Locomotion velocity, session 36.47.58.02.52.8-2.72.7-2.72.72.82.72.82.82.8
Locomotion distance, session 30.00.00.1-0.30.1-0.00.1-0.00.2-0.0-0.1-0.00.1-0.0
Stereotopy head waving bouts, day 34.65.57.82.82.4-2.32.2-2.22.22.32.32.32.32.3
Stereotopy head waving duration, day 35.76.98.42.92.6-2.62.5-2.52.52.62.62.62.62.6
Locomotion velocity, session 70.60.70.90.60.9-0.90.8-0.80.80.80.80.90.90.8
Locomotion distance, session 70.10.10.8-0.9-0.20.1-0.10.10.0-0.1-0.1-0.1-0.0-0.1
Stereotopy head waving bouts, day 70.10.10.40.60.00.2-0.30.3-0.2-0.2-0.2-0.2-0.3-0.2
Stereotopy head waving duration, day 70.10.11.21.10.4-0.20.1-0.10.10.10.10.10.10.1
Locomotion velocity, session 80.30.42.41.60.7-0.40.3-0.30.30.40.40.40.40.4
Locomotion distance, session 80.10.10.80.90.3-0.20.2-0.20.10.20.20.20.30.2
Degree of sensitization distance0.40.40.4-0.5-0.70.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6
Degree of sensitization stereotypy2.32.52.9-1.1-1.41.6-1.61.6-1.6-1.7-1.7-1.7-1.7-1.7
Conditioned locomotion1.11.33.0-1.7-1.41.1-1.11.0-1.1-0.9-0.9-0.9-0.9-1.0
Cocaine response after cond. corrected4.34.910.1-3.2-2.42.2-2.02.1-2.1-1.9-2.0-2.0-2.0-2.1
Cocaine response after cond. not corrected4.65.110.7-3.3-2.52.2-2.12.1-2.1-1.9-2.0-2.1-2.0-2.1
Cocaine response before conditioning0.40.50.80.90.8-0.70.6-0.70.60.70.70.70.60.7
Saline control response0.00.00.1-0.3-0.30.2-0.20.1-0.2-0.1-0.2-0.2-0.0-0.1
Bone: connectivity density0.50.81.20.2-0.40.8-1.01.0-0.9-1.1-1.1-1.0-1.0-1.0
Bone: cortical apparent density0.81.11.4-1.0-1.21.0-1.01.0-1.1-1.1-1.1-1.1-1.0-1.0
Bone: cortical area0.81.11.5-0.4-0.91.1-1.11.1-1.2-1.2-1.2-1.1-1.1-1.1
Bone: cortical porosity0.40.51.31.10.8-0.70.6-0.60.60.60.60.60.50.6
Bone: cortical porosity0.10.10.70.80.10.1-0.10.1-0.1-0.2-0.2-0.2-0.2-0.1
Bone: cortical thickness1.32.12.4-0.9-1.41.4-1.51.5-1.6-1.5-1.5-1.4-1.5-1.5
Bone: cortical thickness0.10.10.3-0.50.0-0.20.3-0.30.20.30.30.30.30.3
Bone: cortical tissue density0.60.70.9-0.9-1.00.8-0.80.8-0.9-0.9-0.9-0.9-0.8-0.8
Condit. Reinf. active minus inactive responses4.14.64.92.12.2-2.22.2-2.12.22.12.12.12.12.2
Condit. Reinf. active-inactive response ratio2.42.52.91.11.6-1.61.7-1.61.71.61.61.61.61.7
Condit. Reinf. active responses3.24.06.92.62.1-2.01.9-1.91.91.81.81.91.91.9
Condit. Reinf. inactive responses0.60.73.31.80.9-0.70.7-0.60.60.60.60.70.70.6
Incentive salience index mean1.92.33.92.01.7-1.51.5-1.41.51.41.41.41.41.4
Condit. Reinf. lever presses0.20.21.31.20.10.2-0.20.4-0.2-0.4-0.4-0.4-0.4-0.3
Condit. Reinf. active minus inactive responses2.73.33.81.11.8-1.91.9-1.91.91.91.81.91.81.9
Condit. Reinf. active-inactive response ratio0.30.30.4-0.40.3-0.50.7-0.60.70.60.60.60.60.6
Condit. Reinf. active responses2.33.23.51.41.9-1.91.9-1.81.91.81.81.81.81.8
Condit. Reinf. inactive responses1.11.31.71.31.3-1.21.1-1.11.11.21.11.11.01.1
Condit. Reinf. lever presses2.73.74.31.21.9-1.92.0-2.02.02.12.02.02.02.0
Condit. Reinf. lever reinforcers received1.92.62.91.11.6-1.71.7-1.71.71.71.61.61.61.7
Conditioned reinforcement - actives2.32.33.01.31.7-1.71.6-1.71.71.41.41.41.31.3
Conditioned reinforcement - inactives0.40.51.1-1.1-0.80.7-0.60.5-0.6-0.6-0.6-0.6-0.7-0.8
Conditioned locomotion7.59.110.82.73.3-3.23.3-3.13.22.92.92.92.82.8
Patch foraging indifference point 0 sec0.20.30.4-0.3-0.60.5-0.50.5-0.6-0.5-0.5-0.5-0.5-0.5
Patch foraging indifference point AUC1.01.21.40.91.2-1.21.2-1.11.21.01.11.01.01.0
Delay disc. indifference point, 0s delay8.39.110.1-2.0-2.93.1-3.13.1-3.1-3.2-3.2-3.2-3.2-3.1
Delay disc. indifference point, 16s delay0.20.20.3-0.5-0.40.4-0.50.6-0.4-0.4-0.4-0.4-0.4-0.4
Delay disc. indifference point, 2s delay6.57.27.7-2.4-2.62.7-2.72.7-2.7-2.8-2.8-2.8-2.8-2.6
Delay disc. indifference point, 24s delay0.60.61.0-0.9-0.70.8-0.81.0-0.7-0.7-0.7-0.7-0.7-0.8
Delay disc. indifference point, 4s delay1.51.52.0-1.2-1.11.3-1.31.4-1.3-1.2-1.2-1.2-1.2-1.1
Delay disc. indifference point, 8s delay1.11.11.8-1.3-1.11.0-1.01.1-1.0-1.0-1.0-1.0-1.0-0.8
Indifference point function ln k0.30.40.7-0.9-0.60.6-0.60.5-0.6-0.5-0.6-0.6-0.5-0.6
Indifference point function log k0.30.40.7-0.9-0.60.6-0.60.5-0.6-0.5-0.6-0.6-0.5-0.6
Patch foraging total patch changes 0 sec0.10.20.3-0.3-0.50.4-0.40.4-0.5-0.4-0.4-0.4-0.4-0.3
Patch foraging total patch changes 12 sec0.20.20.9-0.9-0.70.5-0.40.4-0.5-0.4-0.3-0.4-0.4-0.4
Patch foraging total patch changes 18 sec1.21.51.71.21.2-1.21.2-1.31.21.21.21.21.31.3
Patch foraging total patch changes 24 sec0.10.10.20.40.3-0.30.3-0.30.30.30.30.30.20.3
Patch foraging total patch changes 6 sec0.20.30.90.90.4-0.50.6-0.60.40.50.60.60.60.6
Patch foraging time to switch 0 sec1.72.73.6-0.4-1.71.7-1.81.8-1.9-1.6-1.6-1.6-1.6-1.7
Patch foraging water rate 0 sec0.20.31.0-1.00.2-0.40.5-0.60.60.30.30.30.30.5
Patch foraging water rate 12 sec0.61.04.0-2.0-1.10.9-0.80.8-0.7-0.7-0.8-0.8-0.7-0.7
Patch foraging water rate 18 sec0.60.81.5-1.20.4-0.70.9-1.00.90.90.80.80.81.0
Patch foraging water rate 24 sec0.30.44.5-2.1-0.50.10.1-0.10.1-0.0-0.1-0.1-0.00.1
Patch foraging water rate 6 sec0.71.01.3-0.40.8-1.01.1-1.11.11.01.01.01.11.1
Seeking ratio, delayed vs. immediate footshock4.45.06.32.42.5-2.32.2-2.22.32.12.12.12.12.2
Distance traveled before self-admin0.50.60.9-0.5-0.50.6-0.60.7-0.6-0.9-0.9-0.9-0.9-0.9
Distance traveled after self-admin0.60.71.10.91.0-0.91.0-0.80.90.80.70.70.70.7
Extensor digitorum longus weight4.417.323.1-4.8-4.34.1-3.94.1-3.9-4.1-4.1-4.0-4.2-4.1
Bone: elastic displacement0.20.30.40.60.6-0.50.5-0.50.60.50.50.50.50.5
Bone: elastic work0.20.30.4-0.4-0.40.6-0.60.6-0.6-0.6-0.6-0.6-0.6-0.6
Bone: endosteal estimation0.30.60.7-0.5-0.60.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8
Bone: endosteal perimeter0.10.30.80.90.7-0.50.4-0.40.40.50.50.40.50.4
Epididymis fat weight0.20.50.70.30.6-0.70.8-0.80.70.80.80.80.80.8
Delta time in closed arm before/after self-admin0.50.53.5-1.9-0.70.4-0.50.3-0.3-0.4-0.4-0.4-0.4-0.4
Delta time in open arm before/after self-admin1.21.21.6-0.5-1.21.2-1.11.3-1.2-1.1-1.1-1.1-1.0-1.0
Diff in mean of infusions in LGA sessions1.82.02.31.31.4-1.41.4-1.41.41.51.41.41.51.5
Delay discount exponential model param2.32.43.01.71.5-1.61.6-1.71.51.51.51.51.51.4
Extinction: sum of active levers before priming1.51.52.30.31.2-1.31.5-1.51.41.21.21.21.11.2
Active lever presses in extinction session 63.02.94.31.51.9-1.82.1-1.81.81.61.61.61.51.6
Bone: final force1.52.42.8-0.9-1.41.6-1.61.6-1.7-1.6-1.6-1.6-1.6-1.6
Bone: final moment1.11.92.3-0.8-1.31.4-1.41.4-1.5-1.4-1.4-1.4-1.4-1.4
Food consumed during 24 hour testing period0.60.81.5-1.2-0.80.8-0.70.7-0.7-1.0-1.0-0.9-0.9-0.7
Glucose1.32.02.4-1.6-1.41.4-1.31.4-1.3-1.4-1.4-1.4-1.4-1.4
Heart weight0.40.60.70.40.7-0.80.8-0.80.90.80.80.80.90.8
Delay discount hyperbolic model param3.23.43.91.91.8-1.91.9-2.01.81.91.91.81.91.6
Intermittent access intake day 1-15 change7.47.38.02.32.7-2.82.8-2.82.82.72.72.72.62.7
Intermittent access intake escalation7.67.48.61.92.6-2.82.9-2.92.92.72.72.72.72.7
Intermittent access intake escalation 29.59.310.42.22.9-3.13.2-3.23.23.13.13.13.13.1
Intermitt. access day 1 inactive lever presses0.40.41.0-0.10.7-0.71.0-0.70.90.50.50.50.50.5
Intermitt. access day 15 inactive lever presses0.60.71.00.60.7-0.81.0-0.80.80.90.90.90.80.8
Intermitt. access escalation Index0.50.40.60.2-0.40.6-0.70.7-0.7-0.8-0.8-0.8-0.8-0.6
Intermittent access day 1 total infusions0.10.10.1-0.3-0.30.3-0.10.2-0.3-0.2-0.2-0.2-0.3-0.4
Intermittent access day 15 total infusions2.32.53.11.01.5-1.61.8-1.81.71.71.71.71.61.5
Intermittent access terminal intake (last 3 days)1.31.41.70.81.2-1.21.3-1.31.21.21.21.21.11.0
Intermittent access total infusions0.20.30.50.20.5-0.60.6-0.70.60.50.50.50.50.4
Intermittent access day 1 locomotion0.40.40.50.50.6-0.60.6-0.70.60.70.70.70.60.6
Intermittent access day 15 total locomotion3.94.24.91.82.1-2.12.2-2.12.22.02.02.02.01.9
Intermittent access total locomotion1.01.11.41.01.2-1.21.2-1.21.21.01.01.00.90.8
Intermittent access standard deviation3.53.74.61.42.0-2.02.1-2.12.11.91.91.91.81.7
Left kidney weight0.00.00.40.60.3-0.10.0-0.00.10.10.10.10.10.0
Right kidney weight1.44.04.92.22.1-2.02.0-2.02.02.02.02.02.01.9
Cocaine induced anxiety0.50.51.61.30.9-0.70.6-0.60.60.70.70.70.50.4
Post-drug Anxiety0.30.41.51.20.6-0.40.3-0.30.30.70.70.70.60.5
Baseline Anxiety0.20.20.4-0.00.2-0.30.3-0.30.30.60.60.60.70.6
Tail length3.410.311.02.63.2-3.33.2-3.23.33.33.33.23.33.2
Length with tail1.96.98.12.82.7-2.62.5-2.62.62.62.62.62.62.5
Length without tail0.10.11.11.10.3-0.1-0.1-0.00.10.00.00.00.00.0
Times rat made contact with spout0.10.20.8-0.9-0.50.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3
Lifetime Intake0.10.10.20.10.3-0.30.4-0.50.30.30.30.30.20.1
Liver weight, left2.33.74.6-2.1-2.02.0-2.01.9-1.9-1.8-1.8-1.8-1.8-1.8
Liver weight, right1.83.03.3-1.6-1.71.8-1.81.7-1.7-1.7-1.7-1.7-1.8-1.8
Locomotor activity3.04.78.22.92.4-2.22.1-2.12.02.02.02.12.02.0
Locomotor testing distance1.93.14.42.11.9-1.81.7-1.81.71.71.71.71.71.7
Locomotor testing rearing0.10.10.2-0.20.2-0.30.3-0.30.30.40.40.40.40.4
Locomotion in novel chamber0.40.50.70.30.8-0.80.8-0.80.80.60.60.60.70.6
Locomotion in novel chamber post-restriction0.70.91.00.60.9-1.01.0-1.00.91.01.01.01.01.0
Fecal boli incidents, locomotor time 11.41.52.0-1.2-1.41.3-1.11.1-1.2-1.2-1.2-1.2-1.2-1.3
Change in fecal boli incidents, locomotor task0.10.10.30.40.6-0.40.4-0.40.30.30.30.30.30.2
Time >=10cm from walls, locomotor time 10.50.51.00.1-0.50.6-0.70.7-0.7-0.7-0.7-0.7-0.7-1.0
Bouts of movement, locomotor time 10.20.20.20.40.4-0.50.5-0.50.50.50.50.50.50.3
Total resting periods, locomotor time 10.20.30.30.60.6-0.50.5-0.50.50.50.50.50.50.4
Rest time, locomotor task time 10.10.20.30.50.4-0.40.5-0.50.40.30.30.30.40.2
Distance moved, locomotor task time 10.60.60.8-0.3-0.60.8-0.90.9-0.8-0.8-0.8-0.8-0.8-0.8
Vertical activity count, locomotor time 10.10.10.4-0.7-0.30.2-0.10.1-0.2-0.2-0.2-0.2-0.2-0.1
Time >=10cm from walls, locomotor time 20.91.01.2-1.1-1.11.0-1.01.0-0.9-1.0-1.0-1.0-0.9-1.0
Bouts of movement, locomotor time 20.30.31.81.40.6-0.40.3-0.30.40.30.30.30.40.5
Total resting periods, locomotor time 20.30.31.71.30.6-0.40.2-0.20.30.30.30.30.30.4
Rest time, locomotor task time 20.40.51.11.10.8-0.70.5-0.50.60.70.70.70.60.6
Distance moved, locomotor task time 20.60.71.5-1.2-1.00.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8
Vertical activity count, locomotor time 20.50.61.8-1.3-0.90.7-0.50.5-0.6-0.7-0.7-0.7-0.6-0.7
Light reinforcement 15.710.412.93.63.3-3.23.1-3.13.23.23.13.23.23.2
Light reinforcement 21.82.43.31.81.6-1.61.5-1.51.51.51.51.61.51.6
Bone: marrow area0.30.60.7-0.5-0.70.8-0.80.8-0.8-0.8-0.8-0.8-0.8-0.8
Bone: maximum diameter0.40.82.41.51.0-0.90.8-0.80.70.80.80.80.70.8
Bone: maximum force1.42.43.0-1.1-1.51.6-1.61.6-1.7-1.5-1.5-1.5-1.6-1.6
Bone: maximum moment1.12.02.5-1.0-1.41.4-1.51.5-1.6-1.4-1.4-1.4-1.4-1.5
Mean time between licks in bursts4.66.57.32.12.5-2.62.6-2.62.62.62.72.62.72.6
Mean num. licks in bursts0.10.10.10.1-0.10.3-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3
Cd content in liver0.20.20.3-0.4-0.50.5-0.50.5-0.5-0.5-0.5-0.5-0.5-0.5
Co content in liver0.60.80.90.70.8-0.90.9-0.90.90.90.90.80.90.9
Cu content in liver0.20.20.30.2-0.30.5-0.50.6-0.5-0.5-0.5-0.5-0.5-0.6
Fe content in liver0.00.10.1-0.10.1-0.20.2-0.30.20.30.20.20.30.3
K content in liver0.10.10.60.80.00.2-0.20.3-0.2-0.3-0.3-0.4-0.3-0.3
Mg content in liver0.10.10.40.70.00.2-0.20.4-0.2-0.3-0.4-0.4-0.3-0.4
Mn content in liver0.50.63.51.91.0-0.60.5-0.50.50.50.40.40.50.5
Na content in liver1.31.41.9-0.2-1.11.2-1.21.2-1.2-1.3-1.3-1.4-1.2-1.2
Rb content in liver0.60.81.00.0-0.60.8-0.90.9-0.9-1.0-0.9-1.0-1.0-0.9
Se content in liver0.10.10.30.50.5-0.40.4-0.40.40.30.30.20.30.4
Sr content in liver0.10.10.2-0.40.0-0.20.3-0.30.30.20.20.20.20.3
Zn content in liver2.42.73.50.51.5-1.71.9-1.81.91.71.61.61.61.8
Bone: minimum diameter0.00.10.10.2-0.10.2-0.30.3-0.3-0.3-0.3-0.3-0.3-0.3
Time in familiar zone, hab. session 12.72.53.11.11.5-1.51.5-1.61.51.81.81.71.71.7
Time in novel zone, hab. session 11.41.41.8-0.7-1.01.1-1.11.2-1.2-1.3-1.3-1.3-1.3-1.3
Total zone transitions, hab. session 10.60.82.81.71.0-0.80.8-0.70.70.80.80.70.80.8
Total locomotion distance, hab. session 10.70.94.32.11.1-0.80.6-0.60.60.80.80.70.80.7
Locomotion velocity, hab. session 11.11.65.72.41.4-1.11.0-1.01.01.11.11.11.11.1
Time in familiar zone, hab. session 27.27.48.22.02.7-2.72.7-2.82.82.82.82.82.92.8
Time in novel zone, hab. session 25.55.56.2-1.7-2.22.3-2.42.4-2.4-2.4-2.4-2.4-2.5-2.4
Total zone transitions, hab. session 20.40.60.70.8-0.50.7-0.80.8-0.9-0.7-0.8-0.8-0.7-0.8
Total locomotion distance, hab. session 20.71.04.22.10.9-0.80.7-0.70.70.90.80.80.80.8
Locomotion velocity, hab. session 20.70.94.82.20.9-0.70.6-0.60.60.70.70.70.70.7
Novel to familiar place preference ratio5.05.16.1-1.6-2.02.2-2.32.3-2.3-2.4-2.4-2.4-2.5-2.4
Novelty place preference3.13.23.9-1.2-1.51.8-1.81.9-1.7-1.9-1.9-1.9-2.0-1.9
Time in novel zone, NPP test3.53.64.3-1.3-1.61.9-1.92.0-1.9-2.0-2.0-2.0-2.1-2.0
Total zone transitions, NPP test0.10.10.80.9-0.20.3-0.30.3-0.3-0.2-0.2-0.2-0.1-0.2
Total locomotion distance, NPP test0.20.20.80.9-0.20.4-0.50.5-0.5-0.3-0.3-0.4-0.3-0.4
Locomotion velocity, NPP test0.10.11.41.20.10.1-0.20.2-0.2-0.0-0.1-0.1-0.0-0.1
Intraocular pressure0.20.20.5-0.70.2-0.40.5-0.50.50.50.50.50.50.5
Delta distance traveled before/after self-admin1.81.92.21.41.3-1.31.4-1.31.31.51.51.51.41.5
Delta ambulatory time before/after self-admin1.81.92.31.51.4-1.41.3-1.31.31.41.41.41.31.4
Parametrial fat weight0.50.91.10.51.0-1.01.0-1.11.11.01.01.01.00.9
Pavlov. Cond. lever latency0.10.10.4-0.60.1-0.30.4-0.40.30.30.30.30.40.3
Pavlov. Cond. magazine entry latency3.13.94.31.91.9-2.02.0-2.01.92.02.02.12.02.0
Pavlov. Cond. change in total contacts0.00.10.10.40.3-0.20.2-0.20.20.20.20.20.10.2
Pavlov. Cond. index score0.30.41.31.10.7-0.60.5-0.50.50.50.50.60.40.6
Pavlov. Cond. latency score0.30.31.51.20.6-0.50.4-0.40.40.40.40.50.30.5
Pavlov. Cond. lever contacts0.10.10.80.90.20.1-0.20.2-0.1-0.2-0.2-0.2-0.3-0.1
Pavlov. Cond. magazine entry number0.70.81.0-1.0-0.90.9-0.90.9-0.8-0.9-0.9-1.0-0.8-1.0
Pavlov. Cond. intertrial magazine entries0.20.20.3-0.00.3-0.50.6-0.60.50.50.50.50.60.5
Pavlov. Cond. lever-magazine prob. diff.0.60.81.81.30.9-0.80.8-0.80.80.80.80.90.70.9
Pavlov. Cond. response bias1.11.31.71.31.1-1.11.1-1.11.11.11.11.21.01.2
Pavlov. Cond. lever latency0.91.21.4-0.8-1.21.1-1.01.1-1.1-1.2-1.2-1.2-1.0-1.1
Pavlov. Cond. magazine entry latency0.50.50.80.50.9-0.70.7-0.70.70.70.70.80.70.7
Pavlov. Cond. change in total contacts0.91.21.40.71.2-1.11.1-1.11.21.11.11.11.11.1
Pavlov. Cond. index score1.01.31.50.71.2-1.11.1-1.11.21.21.21.21.21.1
Pavlov. Cond. latency score0.91.11.30.81.2-1.11.0-1.01.01.11.11.11.11.0
Pavlov. Cond. lever contacts0.91.21.50.61.1-1.11.1-1.11.11.21.21.21.11.1
Pavlov. Cond. magazine entry number0.70.91.3-0.6-1.21.0-1.00.9-1.0-1.0-1.0-1.0-1.0-0.9
Pavlov. Cond. intertrial magazine entries0.20.30.7-0.8-0.80.5-0.40.4-0.5-0.4-0.4-0.4-0.4-0.4
Pavlov. Cond. lever-magazine prob. diff.1.01.21.50.81.2-1.11.1-1.11.11.21.21.21.21.1
Pavlov. Cond. response bias2.12.83.21.11.7-1.71.7-1.71.71.81.81.81.71.7
Time in closed arm before self-admin1.11.21.5-0.1-1.01.1-1.21.2-1.2-1.2-1.2-1.2-1.2-1.2
Time in closed arm after self-admin0.00.00.0-0.10.0-0.1-0.0-0.10.00.10.10.10.10.2
Time in open arm before self-admin0.91.01.50.41.2-1.11.1-1.11.20.90.90.90.90.8
Time in open arm after self-admin0.70.80.9-0.9-0.90.9-0.80.9-0.8-0.9-0.9-0.9-0.8-0.9
Bone: periosteal estimation0.51.01.3-0.3-0.81.0-1.11.1-1.2-1.1-1.1-1.1-1.1-1.1
Bone: periosteal perimeter0.00.10.50.70.2-0.1-0.00.0-0.1-0.0-0.0-0.0-0.0-0.0
Bone: post-yield work0.50.71.0-0.9-1.00.9-0.80.8-0.9-0.8-0.8-0.8-0.8-0.8
Progressive ratio test 1 active lever presses0.10.10.3-0.6-0.30.2-0.20.1-0.2-0.2-0.2-0.2-0.2-0.3
Progressive ratio test 1 breakpoint0.10.10.4-0.6-0.40.3-0.40.2-0.4-0.3-0.3-0.3-0.3-0.4
Progressive ratio test 1 inactive lever presses0.00.00.10.10.1-0.10.2-0.10.10.00.00.0-0.0-0.1
Progressive ratio test 2 active lever presses0.30.30.5-0.10.6-0.60.6-0.70.70.50.50.50.50.4
Progressive ratio test 2 breakpoint0.30.30.50.20.7-0.60.6-0.70.70.50.50.50.50.4
Progressive ratio test 2 inactive lever presses0.00.00.10.20.3-0.20.3-0.30.20.20.20.20.1-0.0
Incentive Sensitization - Responses0.30.30.6-0.10.7-0.70.7-0.70.80.40.40.40.40.4
Incentive Sensitization - Breakpoint0.30.30.60.00.7-0.70.7-0.70.80.50.50.50.50.5
Sum of active levers in priming session hrs 5-60.00.00.1-0.00.0-0.00.3-0.10.1-0.0-0.0-0.0-0.1-0.1
Progressive ratio0.10.10.2-0.4-0.40.4-0.40.4-0.3-0.3-0.3-0.3-0.3-0.4
Food seeking constrained by brief footshock0.10.10.40.60.3-0.30.3-0.30.30.30.30.30.30.3
Seeking ratio, punishment vs. effort0.10.10.30.60.3-0.40.3-0.30.20.30.20.20.30.4
Retroperitoneal fat weight0.31.01.5-1.2-1.21.0-1.01.0-1.0-0.9-0.9-0.9-0.9-0.9
Reaction time number correct0.40.63.0-1.7-0.80.6-0.50.5-0.5-0.7-0.7-0.6-0.6-0.5
Reaction time mean minus median0.81.11.30.71.1-1.01.0-1.01.11.11.01.01.11.0
Reaction time mean minus median AUC0.00.00.10.40.20.1-0.20.2-0.1-0.1-0.2-0.2-0.1-0.2
Reaction time num false alarms0.10.10.9-1.0-0.20.1-0.00.1-0.1-0.2-0.2-0.1-0.2-0.1
Reaction time num false alarms AUC0.10.21.4-1.2-0.30.2-0.10.1-0.1-0.2-0.2-0.2-0.2-0.1
Reaction time trials correct on left0.40.63.0-1.7-0.80.6-0.50.5-0.5-0.7-0.7-0.6-0.6-0.5
Reaction time trials on left0.40.62.9-1.7-0.90.6-0.60.5-0.6-0.7-0.7-0.7-0.7-0.5
Reaction time mean0.00.00.10.2-0.00.1-0.20.2-0.2-0.0-0.0-0.10.0-0.2
Reaction time mean AUC0.00.10.10.2-0.10.2-0.30.3-0.3-0.1-0.1-0.2-0.1-0.3
Median of all reaction times0.30.40.6-0.2-0.60.7-0.80.8-0.8-0.6-0.6-0.6-0.5-0.7
Reaction time omissions0.20.30.50.70.6-0.60.6-0.50.60.40.40.40.40.4
Reaction time false alarm rate0.00.00.1-0.3-0.10.1-0.00.1-0.1-0.1-0.1-0.1-0.1-0.1
Reaction time premature initiation rate1.41.82.20.91.1-1.31.4-1.41.31.51.51.51.41.4
Reaction time premature initiations0.91.21.70.00.7-1.11.2-1.31.11.21.21.21.21.3
Std. dev. reaction times0.20.30.40.60.7-0.50.5-0.50.50.60.50.50.60.5
Reaction time trials completed0.40.62.9-1.7-0.90.6-0.60.5-0.6-0.7-0.7-0.7-0.7-0.5
Reaction time trials AUC0.40.63.1-1.8-0.80.6-0.50.4-0.5-0.6-0.6-0.6-0.6-0.4
Run reversals in cocaine runway, females0.30.30.50.70.7-0.60.5-0.50.50.50.50.50.50.5
Run reversals in cocaine runway, males1.21.12.01.41.1-1.01.0-1.00.91.01.01.01.01.1
Latency to leave start box in cocaine runway0.70.71.91.41.1-0.90.9-0.80.80.70.70.70.70.6
Latency to leave start box in cocaine runway, F0.20.20.50.70.00.2-0.20.2-0.4-0.4-0.5-0.5-0.4-0.6
Latency to leave start box in cocaine runway, M3.53.43.91.01.8-1.91.9-1.92.01.91.91.91.91.9
Std. dev. time between licks in bursts0.60.81.11.01.0-0.90.8-0.80.80.90.90.81.00.8
Total sessions with >9 infusions0.00.10.20.00.10.0-0.1-0.0-0.1-0.3-0.3-0.3-0.3-0.4
Short access day 1 total inactive lever presses0.00.00.10.30.2-0.20.2-0.30.20.10.10.10.0-0.0
Short access day 10 total inactive lever presses0.10.10.4-0.10.3-0.30.6-0.30.40.20.20.20.10.1
Short access day 1 total infusions0.10.10.50.70.4-0.20.2-0.30.10.20.20.20.1-0.0
Short access day 10 total infusions0.00.00.1-0.20.1-0.20.3-0.30.20.10.10.10.1-0.0
Short access total infusions0.00.00.10.00.1-0.0-0.0-0.1-0.0-0.1-0.1-0.1-0.1-0.2
Short access day 1 locomotion0.80.91.51.21.0-1.01.0-1.00.90.90.90.90.80.6
Short access day 10 total locomotion4.14.66.11.82.3-2.42.3-2.52.42.02.02.02.02.0
Short access total locomotion0.80.91.30.91.1-1.01.0-1.11.00.80.80.80.80.6
One hour access (0.3 mA shock)0.20.20.4-0.5-0.50.4-0.40.3-0.4-0.4-0.4-0.4-0.5-0.6
Compulsive drug intake1.41.51.7-0.8-1.11.2-1.31.2-1.2-1.3-1.3-1.3-1.3-1.3
One hour access (shock baseline)0.10.10.2-0.10.2-0.30.4-0.50.40.40.40.40.30.2
Social response proportion0.60.72.21.50.8-0.70.7-0.60.60.70.70.80.70.7
Social responses6.88.711.73.43.2-2.92.9-2.82.92.92.82.82.92.8
Social time0.50.71.0-0.7-1.00.9-0.90.9-0.9-0.7-0.8-0.8-0.7-0.9
Soleus weight9.327.227.8-5.1-5.35.3-5.25.2-5.2-5.2-5.2-5.2-5.2-5.2
Bone: stiffness3.35.36.0-1.9-2.32.3-2.32.3-2.5-2.3-2.3-2.3-2.3-2.3
Tibialis anterior weight1.24.24.9-2.1-1.82.0-1.92.1-1.8-2.2-2.1-2.1-2.2-2.1
Time to tail flick, vehicle, before self-admin0.30.31.51.20.8-0.50.4-0.40.50.30.40.40.40.5
Time to tail flick, vehicle, after self-admin0.30.30.6-0.10.2-0.40.4-0.50.40.60.60.60.80.8
Time to tail flick, test, before self-admin0.10.10.90.90.4-0.2-0.1-0.20.10.20.20.20.20.1
Time to tail flick, test, after self-admin0.20.20.80.90.5-0.30.1-0.30.30.30.30.30.50.6
Delta time to tail flick, vehicle, before/after SA0.30.31.7-1.3-0.70.4-0.30.3-0.4-0.1-0.2-0.2-0.1-0.2
Delta time to tail flick, test, before/after SA0.20.20.40.10.3-0.40.4-0.40.50.40.50.50.50.6
Tibia length1.13.03.51.41.7-1.71.7-1.71.81.91.81.81.81.7
Ambulatory time before self-admin0.40.40.7-0.5-0.40.5-0.50.6-0.5-0.8-0.8-0.8-0.8-0.8
Ambulatory time after self-admin0.30.40.70.70.8-0.70.9-0.60.70.50.50.50.40.4
Bone: tissue strength1.81.72.1-0.9-1.41.4-1.41.4-1.4-1.3-1.3-1.3-1.3-1.4
Total heroin consumption2.02.43.11.41.6-1.61.8-1.61.61.51.51.51.51.5
Bone: trabecular number0.40.62.51.61.1-0.70.6-0.60.70.50.50.50.50.6
Bone: trabecular spacing0.20.32.9-1.7-0.70.3-0.10.1-0.1-0.0-0.0-0.1-0.0-0.1
Bone: trabecular thickness0.50.62.01.40.10.5-0.70.7-0.7-0.7-0.7-0.7-0.8-0.7
Bone: trabecular tissue density1.42.03.3-1.5-1.81.5-1.41.4-1.5-1.3-1.3-1.3-1.3-1.4
Water consumed over 24 hours0.80.91.2-0.5-0.80.9-1.01.0-1.0-1.1-1.1-1.0-1.1-1.0
Number of responses in last shaping day0.10.10.40.20.5-0.40.5-0.60.40.30.30.30.20.1