Hub : Genes

Gnb5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Gnb5 0.38 0.1 0.0e+00 0.25 0.28 0.3 0.15 6.2e-28 2.0e-31 1.0e-33 1.1e-16
2 Liver mRNA stability Gnb5 0.06 0.03 2.9e-04 0.04 0.03 0.02 0.01 3.1e-05 6.4e-04 4.3e-03 1.7e-02
3 Eye gene expression Gnb5 0.54 0.16 4.8e-05 0.11 0.15 0.12 0.12 8.9e-03 2.5e-03 7.1e-03 6.3e-03
4 IL gene expression Gnb5 0.78 0.09 1.2e-11 0.34 0.34 0.32 0.32 5.2e-09 4.9e-09 2.0e-08 2.1e-08
5 NAcc gene expression Gnb5 0.42 0.12 0.0e+00 0.26 0.3 0.31 0.32 1.6e-29 3.5e-35 1.4e-36 2.6e-37
6 PL gene expression Gnb5 0.69 0.09 0.0e+00 0.39 0.51 0.51 0.51 4.5e-46 4.2e-65 3.3e-64 1.4e-64
7 BLA gene expression Gnb5 0.74 0.1 0.0e+00 0.4 0.44 0.45 0.45 6.5e-23 4.7e-26 2.3e-26 1.5e-26
8 OFC mRNA stability Gnb5 0.12 0.07 7.2e-03 0.06 0.04 0.04 0.04 1.5e-02 4.5e-02 4.5e-02 5.3e-02
9 BLA mRNA stability Gnb5 0.07 0.04 1.2e-03 0.01 0.03 0.02 0.02 9.5e-02 6.4e-03 2.0e-02 3.8e-02
10 OFC gene expression Gnb5 0.89 0.05 1.7e-16 0.33 0.35 0.33 0.36 1.3e-08 4.6e-09 1.2e-08 2.5e-09
11 LHb gene expression Gnb5 0.63 0.13 6.8e-09 0.3 0.35 0.31 0.34 9.7e-08 3.6e-09 4.5e-08 6.4e-09
12 PL mRNA stability Gnb5 0.1 0.05 2.0e-14 0.11 0.13 0.12 0.13 1.1e-11 2.4e-14 1.4e-13 8.8e-14
13 NAcc mRNA stability Gnb5 0.09 0.05 3.5e-12 0.11 0.12 0.12 0.12 7.8e-13 2.3e-13 6.2e-14 2.9e-13
14 Adipose gene expression Gnb5 0.49 0.11 0.0e+00 0.24 0.23 0.21 0.24 6.6e-26 8.8e-26 4.4e-23 6.5e-26
15 Brain gene expression Gnb5 0.74 0.08 0.0e+00 0.49 0.66 0.69 0.62 1.2e-51 4.9e-82 1.1e-87 5.3e-74
16 pVTA mRNA stability Gnb5 0.17 0.09 1.0e-03 0 0.01 0.04 0 2.5e-01 8.4e-02 9.4e-03 3.3e-01
17 pVTA gene expression Gnb5 0.12 0.07 2.7e-03 0.06 0.05 0.04 0.06 1.6e-03 4.2e-03 8.2e-03 1.5e-03
18 Brain mRNA stability Gnb5 0.34 0.11 0.0e+00 0.31 0.33 0.34 0.34 7.2e-29 7.1e-32 3.7e-32 4.0e-32
19 LHb mRNA stability Gnb5 0.24 0.12 9.2e-04 0.04 0.06 0.11 0.03 3.4e-02 1.9e-02 1.7e-03 6.4e-02
20 Eye mRNA stability Gnb5 0.82 0.08 5.1e-08 0.03 0.15 0.1 0.17 1.0e-01 3.0e-03 1.1e-02 1.4e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.10.10.5-0.0-0.4-0.1-0.10.20.1-0.0-0.00.30.20.20.5-0.40.3-0.2-0.60.5-0.6-0.50.7
Area under the delay curve0.40.42.30.91.5-1.30.4-0.5-0.4-0.2-0.61.0-0.10.50.40.3-0.20.10.4-0.40.3-0.2-0.6
BMI with tail0.51.67.82.12.8-2.50.7-1.00.10.3-2.41.20.51.00.50.20.1-0.61.1-0.60.5-0.5-0.9
BMI without tail0.71.34.21.32.0-1.20.3-1.3-0.8-0.6-0.50.9-0.6-0.4-0.40.7-1.31.02.1-1.61.30.0-1.8
Body weight0.52.08.61.82.9-2.31.4-0.70.30.7-2.10.90.81.2-0.21.0-0.4-0.62.1-1.01.30.2-1.7
Weight adjusted by age1.11.24.70.81.0-1.61.20.00.90.6-1.51.30.91.71.3-0.41.1-1.1-0.00.6-0.7-2.20.1
Bone surface0.91.64.51.50.8-1.9-0.6-0.8-0.4-0.7-1.82.1-0.40.42.0-1.70.5-0.1-1.30.6-1.6-1.81.3
Bone volume0.40.61.81.00.5-1.3-0.3-0.5-0.2-0.4-1.21.4-0.10.31.3-1.00.3-0.2-0.80.2-0.9-1.10.7
Breakpoint value in progressive ratio session0.50.51.40.80.5-1.20.1-0.30.20.0-1.11.20.00.61.2-0.90.6-0.5-0.40.7-1.0-0.70.8
Number of licking bursts1.41.75.01.10.8-1.80.2-0.40.60.1-2.01.80.11.22.0-1.51.3-0.8-0.90.9-1.6-2.21.2
Context. condit. distance diff. score0.40.51.40.90.3-0.9-0.7-0.4-0.4-0.4-1.20.8-0.30.01.0-1.00.4-0.2-1.10.7-1.0-0.30.9
Locomotion velocity, session 10.40.41.50.91.2-0.8-0.1-0.7-0.6-0.4-0.30.5-0.5-0.3-0.10.3-0.90.50.8-0.90.60.2-0.9
Locomotion distance, session 10.30.41.1-1.0-1.00.61.00.80.70.50.90.00.40.5-0.10.50.2-0.30.50.40.1-0.5-0.0
Locomotion velocity, session 20.40.41.51.01.2-1.0-0.1-0.8-0.5-0.6-0.41.1-0.5-0.10.4-0.2-0.50.50.6-0.80.1-0.8-0.5
Locomotion distance, session 20.50.63.6-0.50.10.21.20.20.20.20.90.20.10.2-0.61.2-0.80.31.9-0.91.2-0.2-1.3
Locomotion velocity, session 31.01.22.80.7-0.1-0.5-1.2-0.9-0.9-1.40.01.6-1.4-0.81.4-1.7-0.31.0-1.10.0-1.4-1.61.1
Locomotion distance, session 30.60.72.3-0.6-1.01.0-0.9-0.3-0.8-1.11.50.1-1.3-1.3-0.1-0.4-0.81.2-0.1-0.2-0.2-0.10.3
Stereotopy head waving bouts, day 31.01.25.0-0.2-1.00.1-0.50.50.60.2-0.60.10.10.51.2-1.41.4-0.9-2.21.6-1.7-0.82.0
Stereotopy head waving duration, day 30.70.84.20.6-0.0-0.4-1.2-0.3-0.2-0.4-1.00.2-0.4-0.11.0-1.40.8-0.3-2.00.8-1.4-0.41.4
Locomotion velocity, session 70.00.10.2-0.1-0.40.1-0.10.1-0.1-0.20.10.2-0.2-0.10.3-0.2-0.00.1-0.30.3-0.3-0.20.4
Locomotion distance, session 70.10.10.50.20.1-0.3-0.1-0.2-0.2-0.3-0.20.7-0.3-0.00.5-0.4-0.00.2-0.10.1-0.4-0.50.3
Stereotopy head waving bouts, day 71.92.24.91.30.5-0.9-2.2-1.6-1.6-2.0-0.51.6-2.0-1.41.4-2.2-0.51.4-1.6-0.2-1.6-1.31.1
Stereotopy head waving duration, day 71.92.34.71.50.8-1.1-2.2-1.8-1.7-2.1-0.61.8-2.1-1.41.4-2.1-0.71.5-1.3-0.4-1.5-1.30.9
Locomotion velocity, session 81.21.42.81.51.3-1.1-1.3-1.6-1.4-1.7-0.31.7-1.5-1.10.9-1.1-1.01.4-0.1-1.0-0.5-1.2-0.1
Locomotion distance, session 80.20.31.70.50.0-0.80.2-0.2-0.0-0.2-0.51.3-0.20.30.9-0.60.1-0.0-0.00.3-0.6-1.10.4
Degree of sensitization distance0.60.62.00.50.7-1.00.90.30.81.0-1.40.21.11.30.50.01.0-1.1-0.00.3-0.2-0.40.0
Degree of sensitization stereotypy1.61.73.71.30.7-0.9-1.9-1.6-1.6-1.9-0.41.6-1.8-1.41.2-1.8-0.71.4-1.0-0.4-1.2-1.10.7
Conditioned locomotion1.51.84.0-1.5-1.11.12.01.81.51.80.8-1.51.91.2-1.31.80.5-1.21.20.21.20.9-0.8
Cocaine response after cond. corrected1.11.23.61.91.7-1.7-1.1-1.4-0.9-0.9-1.81.2-0.8-0.31.1-1.2-0.00.3-0.80.1-0.8-0.40.5
Cocaine response after cond. not corrected1.01.15.21.81.7-1.8-0.6-0.9-0.3-0.2-2.31.0-0.20.41.1-1.00.5-0.4-0.90.4-0.8-0.40.6
Cocaine response before conditioning0.60.72.20.40.6-0.91.20.51.01.2-1.50.31.21.50.40.11.0-1.30.10.2-0.1-0.5-0.1
Saline control response0.81.04.80.3-0.5-0.0-1.4-0.3-0.4-0.8-0.30.3-0.6-0.51.0-1.60.70.1-2.21.0-1.6-0.71.6
Bone: connectivity density0.30.52.4-1.1-1.60.90.30.80.60.21.0-0.10.40.20.2-0.30.5-0.2-0.50.7-0.6-0.80.9
Bone: cortical apparent density1.41.94.5-1.0-0.51.9-0.40.1-0.6-0.31.9-1.9-0.4-1.4-2.11.5-1.41.01.1-1.51.71.9-1.5
Bone: cortical area0.30.52.50.3-0.3-0.4-0.50.40.10.2-0.80.10.50.40.8-0.70.9-0.6-1.60.6-0.9-0.41.1
Bone: cortical porosity1.51.73.4-1.4-1.60.81.51.81.81.70.0-0.91.81.60.10.21.7-1.8-0.61.4-0.5-0.31.0
Bone: cortical porosity1.61.83.5-1.5-1.91.01.31.81.81.50.2-0.81.71.50.3-0.11.8-1.7-0.91.7-0.8-0.51.3
Bone: cortical thickness0.60.93.4-1.3-1.51.7-0.31.10.10.41.2-1.90.6-0.5-1.10.80.1-0.2-0.70.10.51.30.2
Bone: cortical thickness0.30.31.7-0.5-0.40.8-0.20.50.20.40.1-1.30.5-0.1-0.70.40.3-0.3-0.50.40.21.20.2
Bone: cortical tissue density1.31.84.3-0.9-0.41.8-0.40.0-0.7-0.31.8-1.9-0.4-1.4-2.11.5-1.41.01.1-1.51.71.8-1.5
Condit. Reinf. active minus inactive responses1.01.14.60.51.1-0.50.5-0.7-0.6-0.40.20.5-0.4-0.5-0.81.0-1.50.92.1-1.81.50.2-2.0
Condit. Reinf. active-inactive response ratio0.50.61.41.11.2-0.6-0.9-1.0-1.0-0.7-0.70.1-0.7-0.8-0.2-0.1-0.80.70.3-1.20.40.4-0.8
Condit. Reinf. active responses0.81.04.50.71.1-0.80.6-0.7-0.6-0.50.11.1-0.6-0.3-0.20.7-1.40.92.1-1.61.1-0.4-1.7
Condit. Reinf. inactive responses0.30.31.80.00.2-0.51.0-0.10.1-0.00.31.1-0.10.40.30.4-0.50.31.3-0.50.3-0.8-0.6
Incentive salience index mean0.50.62.30.20.3-0.91.50.40.90.8-0.81.00.81.30.50.30.4-0.81.1-0.00.1-1.2-0.4
Condit. Reinf. lever presses3.34.411.2-0.8-1.2-0.92.72.02.92.4-1.41.02.53.31.8-0.62.9-2.8-0.62.4-1.7-2.61.8
Condit. Reinf. active minus inactive responses3.03.78.22.82.4-1.8-2.9-2.8-2.6-2.7-1.31.7-2.4-2.10.9-1.7-1.52.1-0.8-1.2-0.6-0.1-0.0
Condit. Reinf. active-inactive response ratio2.32.47.51.91.3-1.0-2.7-2.1-2.1-2.2-0.91.1-2.0-1.90.9-1.8-0.91.6-1.4-0.4-1.00.10.7
Condit. Reinf. active responses1.31.85.92.22.4-1.9-1.2-2.0-1.5-1.4-1.51.5-1.2-0.90.6-0.7-1.11.10.3-1.10.0-0.1-0.7
Condit. Reinf. inactive responses0.60.72.70.10.8-0.81.60.40.91.1-0.80.31.01.3-0.10.90.2-0.81.3-0.30.7-0.4-0.9
Condit. Reinf. lever presses1.42.04.21.91.3-1.8-1.6-1.3-0.9-1.0-2.01.5-0.9-0.21.8-2.00.60.1-1.90.7-1.7-0.91.3
Condit. Reinf. lever reinforcers received1.21.65.62.12.4-1.7-1.2-1.9-1.5-1.3-1.41.2-1.2-0.90.4-0.6-1.11.10.3-1.00.10.1-0.7
Conditioned reinforcement - actives0.80.81.9-0.7-1.10.30.80.91.41.0-0.5-0.10.91.10.5-0.41.3-1.2-0.61.3-0.9-0.71.1
Conditioned reinforcement - inactives0.10.10.5-0.1-0.00.20.1-0.20.10.10.1-0.3-0.1-0.3-0.50.3-0.40.30.7-0.60.4-0.1-0.7
Conditioned locomotion1.11.33.0-1.4-1.21.11.41.61.41.70.4-1.61.51.1-0.91.10.8-1.30.30.60.50.5-0.3
Patch foraging indifference point 0 sec0.50.92.11.21.0-0.7-1.4-1.3-1.3-1.4-0.20.8-1.3-1.00.5-0.8-0.91.0-0.7-0.3-0.40.10.2
Patch foraging indifference point AUC1.61.95.1-1.7-1.01.22.21.61.71.71.1-1.21.51.2-1.21.90.4-1.01.70.21.40.5-0.9
Delay disc. indifference point, 0s delay0.80.92.80.60.9-0.4-0.1-0.9-0.8-0.70.30.6-0.8-0.8-0.50.4-1.41.21.6-1.70.9-0.3-1.6
Delay disc. indifference point, 16s delay0.10.10.4-0.20.40.00.10.1-0.4-0.00.5-0.20.00.1-0.20.6-0.10.1-0.1-0.10.40.2-0.6
Delay disc. indifference point, 2s delay0.60.72.10.81.5-0.8-0.1-0.9-0.9-0.5-0.10.4-0.4-0.4-0.30.6-1.00.81.0-1.30.90.3-1.3
Delay disc. indifference point, 24s delay0.10.10.4-0.20.3-0.00.30.1-0.3-0.10.5-0.0-0.10.1-0.20.6-0.30.10.3-0.20.50.4-0.6
Delay disc. indifference point, 4s delay0.70.82.81.21.7-1.3-0.4-1.2-1.0-1.1-0.51.3-0.9-0.30.6-0.4-0.70.80.2-0.8-0.0-0.5-0.5
Delay disc. indifference point, 8s delay0.80.84.01.51.9-2.00.4-0.8-0.3-0.2-1.31.6-0.20.70.9-0.1-0.1-0.10.4-0.3-0.0-0.5-0.2
Indifference point function ln k2.02.87.22.21.4-1.5-2.7-2.2-2.0-2.2-1.41.6-2.0-1.61.4-2.2-0.61.4-1.7-0.4-1.4-0.80.9
Indifference point function log k2.02.87.22.21.4-1.5-2.7-2.2-2.0-2.2-1.41.6-2.0-1.61.4-2.2-0.61.4-1.7-0.4-1.4-0.80.9
Patch foraging total patch changes 0 sec0.40.61.51.01.0-0.6-1.2-1.1-1.2-1.2-0.10.5-1.1-1.00.2-0.5-0.90.9-0.4-0.4-0.10.4-0.0
Patch foraging total patch changes 12 sec0.91.22.8-1.7-1.21.31.61.51.21.31.3-1.21.10.8-1.01.40.3-0.70.90.40.90.7-0.5
Patch foraging total patch changes 18 sec0.20.30.6-0.7-0.50.60.50.70.60.70.5-0.80.50.4-0.40.50.4-0.5-0.20.60.20.60.2
Patch foraging total patch changes 24 sec1.51.84.80.40.90.2-0.6-1.1-1.4-1.21.2-0.0-1.4-1.6-1.21.0-2.21.81.8-1.91.61.1-1.8
Patch foraging total patch changes 6 sec0.50.71.8-0.00.20.4-0.3-0.5-0.8-0.91.20.1-0.9-1.0-0.70.7-1.41.21.1-1.01.00.4-1.0
Patch foraging time to switch 0 sec0.40.62.7-1.2-1.60.90.31.00.70.50.6-0.50.40.40.1-0.20.7-0.6-0.70.9-0.6-0.20.9
Patch foraging water rate 0 sec1.52.48.32.52.9-1.8-1.6-2.3-1.9-1.6-1.31.1-1.5-1.30.2-0.5-1.51.40.4-1.70.40.3-1.1
Patch foraging water rate 12 sec2.84.39.63.13.1-2.2-2.6-3.1-2.7-2.7-1.32.0-2.5-2.00.9-1.4-1.72.3-0.1-1.8-0.3-0.5-0.6
Patch foraging water rate 18 sec2.63.68.01.42.0-0.2-1.7-2.1-2.4-2.00.6-0.2-1.9-2.5-1.50.8-2.82.41.6-2.71.81.6-2.3
Patch foraging water rate 24 sec1.11.63.51.31.2-0.3-1.7-1.7-1.9-1.80.10.4-1.6-1.9-0.4-0.3-1.71.80.3-1.50.50.4-1.0
Patch foraging water rate 6 sec1.92.86.82.62.6-2.0-1.9-2.4-2.0-2.1-1.41.9-1.8-1.31.0-1.3-1.21.7-0.1-1.3-0.4-0.8-0.4
Seeking ratio, delayed vs. immediate footshock2.22.57.12.01.8-2.5-0.2-1.4-0.2-0.7-1.92.7-0.50.82.4-1.90.7-0.2-0.80.3-1.7-2.71.0
Distance traveled before self-admin1.11.12.81.10.7-1.4-0.8-0.8-0.5-0.8-1.01.6-0.60.11.7-1.60.50.0-1.30.7-1.5-1.11.5
Distance traveled after self-admin1.31.44.31.71.4-2.1-0.4-0.9-0.2-0.4-1.91.8-0.20.61.8-1.40.8-0.4-1.00.5-1.4-0.81.3
Extensor digitorum longus weight0.51.85.82.02.4-2.2-0.0-1.7-0.9-0.9-1.42.0-0.8-0.10.7-0.2-1.10.91.2-1.90.3-1.4-1.3
Bone: elastic displacement0.40.51.3-0.4-0.00.70.40.10.00.20.5-0.90.1-0.3-1.11.0-0.60.21.1-0.61.10.9-1.1
Bone: elastic work0.10.20.6-0.1-0.00.4-0.20.0-0.3-0.10.3-0.60.2-0.5-0.70.5-0.40.30.3-0.20.60.7-0.4
Bone: endosteal estimation1.94.111.22.51.9-3.3-0.4-1.2-0.0-0.4-3.33.1-0.31.33.1-2.51.3-0.8-1.71.1-2.4-2.51.8
Bone: endosteal perimeter1.02.16.11.51.2-2.40.2-0.50.30.1-2.52.10.11.32.2-1.51.2-0.9-1.10.9-1.6-1.81.3
Epididymis fat weight2.76.312.4-3.3-2.43.32.52.51.42.03.2-3.11.70.2-3.43.5-0.8-0.53.2-0.93.02.7-2.4
Delta time in closed arm before/after self-admin0.70.72.2-0.9-0.51.00.60.80.60.90.6-1.50.90.2-1.21.10.0-0.60.70.01.01.3-0.6
Delta time in open arm before/after self-admin1.31.34.0-0.1-1.10.8-2.0-0.6-1.2-1.60.80.3-1.7-1.60.6-1.4-0.51.3-1.60.2-1.1-0.70.5
Diff in mean of infusions in LGA sessions2.52.85.20.80.1-1.80.50.31.20.8-2.21.50.91.92.3-1.82.1-1.7-1.82.0-2.3-2.12.2
Delay discount exponential model param0.50.52.9-1.0-1.71.5-0.30.70.50.40.6-1.10.2-0.4-0.5-0.20.3-0.2-0.40.5-0.30.20.7
Extinction: sum of active levers before priming0.60.61.8-0.2-0.7-0.0-0.10.40.50.2-0.40.30.20.51.0-0.91.0-0.7-1.41.2-1.3-1.01.2
Active lever presses in extinction session 60.70.71.81.10.7-1.0-0.8-0.9-0.4-0.8-0.91.2-0.7-0.21.1-1.30.10.3-0.80.1-1.1-0.90.6
Bone: final force0.00.10.40.40.3-0.6-0.00.1-0.20.1-0.40.30.40.20.30.00.1-0.2-0.3-0.3-0.1-0.1-0.0
Bone: final moment0.00.10.30.2-0.0-0.30.00.4-0.00.3-0.2-0.10.50.20.00.30.2-0.3-0.3-0.10.10.3-0.0
Food consumed during 24 hour testing period2.02.49.82.32.1-2.7-0.6-1.1-0.2-0.2-3.11.7-0.00.92.0-1.61.1-0.8-1.51.0-1.5-0.91.3
Glucose0.10.20.6-0.1-0.10.5-0.7-0.4-0.5-0.60.4-0.2-0.6-0.7-0.2-0.3-0.30.5-0.3-0.7-0.1-0.1-0.0
Heart weight0.81.13.10.61.1-0.2-0.4-0.9-1.0-0.70.3-0.2-0.7-1.0-1.00.8-1.51.21.4-1.81.30.8-1.7
Delay discount hyperbolic model param0.50.52.9-1.1-1.71.4-0.10.80.70.50.6-1.10.3-0.2-0.5-0.10.4-0.3-0.40.6-0.30.20.7
Intermittent access intake day 1-15 change0.20.20.8-0.4-0.3-0.00.90.50.80.70.2-0.10.50.7-0.10.40.3-0.40.50.20.1-0.2-0.1
Intermittent access intake escalation0.40.41.00.10.1-0.70.80.20.80.7-0.70.50.51.00.5-0.20.7-0.70.00.5-0.5-0.80.3
Intermittent access intake escalation 20.60.61.50.60.4-1.20.6-0.00.60.4-1.11.10.31.01.1-0.60.7-0.7-0.30.7-0.9-0.90.8
Intermitt. access day 1 inactive lever presses0.10.10.2-0.2-0.10.30.10.1-0.10.20.3-0.30.0-0.1-0.40.4-0.30.20.4-0.40.40.4-0.4
Intermitt. access day 15 inactive lever presses1.92.04.7-1.7-0.91.31.91.41.11.61.4-1.61.30.8-1.72.2-0.2-0.61.9-0.51.81.1-1.5
Intermitt. access escalation Index0.70.62.21.21.5-1.50.1-0.40.20.2-1.40.50.50.80.6-0.60.7-0.7-0.60.2-0.4-0.70.2
Intermittent access day 1 total infusions1.41.74.5-2.0-2.11.81.11.81.51.60.7-1.81.40.9-0.70.71.1-1.3-0.41.20.00.60.5
Intermittent access day 15 total infusions1.61.83.8-1.6-1.70.81.71.82.01.90.1-1.01.71.7-0.10.41.5-1.7-0.31.5-0.4-0.30.8
Intermittent access terminal intake (last 3 days)1.41.53.5-1.1-1.20.31.61.51.91.9-0.5-0.61.71.80.20.21.6-1.8-0.41.5-0.5-0.60.8
Intermittent access total infusions1.71.93.9-1.6-2.01.01.11.81.81.8-0.1-1.01.61.50.2-0.11.9-1.8-1.12.0-0.9-0.31.5
Intermittent access day 1 locomotion2.52.66.3-2.5-2.32.11.72.31.62.01.4-2.31.81.1-1.51.70.8-1.30.50.81.01.1-0.3
Intermittent access day 15 total locomotion0.70.81.8-1.4-1.31.11.01.21.01.30.6-1.21.00.7-0.70.80.5-0.80.10.50.40.3-0.2
Intermittent access total locomotion0.30.40.8-0.7-0.80.50.60.80.70.90.0-0.60.80.7-0.00.20.8-0.7-0.50.7-0.2-0.20.3
Intermittent access standard deviation1.81.94.9-1.2-1.20.22.21.72.22.1-0.4-0.31.82.20.30.41.6-1.90.21.4-0.4-0.70.7
Left kidney weight0.10.30.80.60.8-0.70.5-0.1-0.00.4-0.60.10.30.2-0.40.6-0.4-0.10.9-0.70.70.5-0.9
Right kidney weight0.10.30.90.30.6-0.61.00.10.50.6-0.60.40.70.80.00.30.2-0.40.8-0.20.3-0.3-0.6
Cocaine induced anxiety0.40.52.0-0.5-0.80.20.70.71.00.5-0.10.10.70.80.5-0.50.9-0.7-0.20.9-0.6-1.40.7
Post-drug Anxiety0.40.41.9-1.2-1.41.20.60.80.70.31.0-0.40.30.1-0.30.20.1-0.00.60.20.1-0.6-0.1
Baseline Anxiety1.51.63.8-0.8-0.41.3-0.3-0.0-0.9-0.41.7-1.2-0.7-1.3-1.71.4-1.71.21.3-1.51.72.0-1.6
Tail length0.30.94.40.30.8-0.30.6-0.5-0.5-0.30.50.4-0.4-0.3-0.71.1-1.30.82.1-1.41.40.3-1.8
Length with tail0.20.62.50.71.2-0.91.0-0.20.10.4-0.60.50.40.5-0.40.9-0.6-0.11.6-1.01.00.2-1.3
Length without tail0.71.43.90.60.7-1.31.10.71.41.4-2.00.31.61.90.9-0.31.5-1.9-0.81.2-0.8-0.40.9
Times rat made contact with spout0.70.83.31.41.3-1.6-0.4-0.7-0.2-0.1-1.81.0-0.10.51.1-0.90.6-0.4-0.80.6-0.8-0.50.7
Lifetime Intake2.22.46.0-2.2-2.41.61.52.22.02.10.4-1.51.81.6-0.20.41.8-1.8-0.71.9-0.50.11.2
Liver weight, left0.10.10.50.60.7-0.6-0.1-0.3-0.10.1-0.60.20.00.10.1-0.00.0-0.1-0.0-0.00.10.4-0.0
Liver weight, right0.50.83.00.31.1-0.30.5-0.4-0.30.20.0-0.1-0.1-0.2-0.91.2-1.00.41.7-1.31.40.8-1.7
Locomotor activity0.10.20.40.20.0-0.40.40.30.60.4-0.60.10.50.60.3-0.10.6-0.6-0.20.6-0.2-0.10.5
Locomotor testing distance0.10.20.70.80.7-0.5-0.8-0.6-0.5-0.7-0.60.3-0.4-0.50.2-0.5-0.20.4-0.4-0.1-0.2-0.00.1
Locomotor testing rearing0.30.51.31.00.9-0.4-1.1-1.0-0.9-1.1-0.20.3-0.9-1.0-0.0-0.3-0.80.9-0.1-0.70.10.1-0.2
Locomotion in novel chamber0.10.10.4-0.4-0.50.5-0.00.40.10.30.3-0.60.2-0.0-0.30.20.1-0.4-0.20.30.00.60.1
Locomotion in novel chamber post-restriction0.20.21.4-0.1-0.20.5-0.2-0.1-0.2-0.10.5-0.5-0.4-0.6-0.70.3-0.60.30.6-0.30.51.2-0.3
Fecal boli incidents, locomotor time 11.51.64.8-0.2-0.1-0.92.21.11.92.0-1.20.41.72.20.50.31.4-1.90.81.1-0.1-0.80.3
Change in fecal boli incidents, locomotor task2.82.67.71.50.7-0.7-2.8-1.7-1.7-2.1-0.81.1-2.0-1.51.5-2.4-0.11.2-2.50.3-1.9-0.81.6
Time >=10cm from walls, locomotor time 10.80.81.60.0-0.2-0.70.70.40.80.6-0.90.80.71.21.2-0.71.3-1.0-0.81.2-1.1-1.21.0
Bouts of movement, locomotor time 10.20.20.9-0.40.3-0.10.90.40.20.50.30.00.50.6-0.30.9-0.1-0.30.7-0.10.60.3-0.6
Total resting periods, locomotor time 10.10.10.4-0.30.2-0.20.70.30.10.40.20.00.30.5-0.10.60.0-0.30.4-0.00.40.2-0.4
Rest time, locomotor task time 10.50.62.11.21.4-0.9-1.0-1.0-1.0-0.6-0.70.2-0.7-0.6-0.0-0.1-0.50.6-0.2-1.10.20.0-0.8
Distance moved, locomotor task time 10.40.41.2-0.6-0.60.80.10.1-0.3-0.31.1-0.3-0.4-0.6-0.80.6-0.90.60.9-0.50.70.6-0.7
Vertical activity count, locomotor time 10.10.10.5-0.6-0.60.50.30.30.10.10.7-0.2-0.0-0.1-0.30.4-0.30.20.5-0.00.30.5-0.1
Time >=10cm from walls, locomotor time 20.40.41.0-0.5-0.50.30.70.71.01.0-0.2-0.70.90.8-0.20.20.9-0.9-0.10.3-0.0-0.3-0.0
Bouts of movement, locomotor time 21.31.43.9-1.1-0.21.01.30.70.40.71.3-1.00.50.1-1.61.9-0.80.12.0-0.81.81.3-1.6
Total resting periods, locomotor time 20.90.92.7-0.9-0.10.81.20.60.30.61.1-0.90.50.2-1.31.6-0.6-0.01.6-0.61.50.9-1.4
Rest time, locomotor task time 20.30.41.7-0.8-0.71.10.00.60.30.50.7-1.30.5-0.2-0.90.60.1-0.1-0.1-0.30.40.2-0.4
Distance moved, locomotor task time 20.70.82.00.50.7-0.4-0.5-1.1-1.1-1.00.40.8-1.3-1.0-0.10.0-1.41.31.0-1.40.5-0.3-1.1
Vertical activity count, locomotor time 20.00.00.10.20.2-0.40.1-0.2-0.00.0-0.20.3-0.10.10.1-0.1-0.10.00.3-0.3-0.0-0.2-0.2
Light reinforcement 10.40.82.20.81.5-1.41.40.00.40.7-0.90.71.01.1-0.10.8-0.2-0.61.4-0.70.8-0.0-1.2
Light reinforcement 22.02.66.3-1.2-1.80.51.12.02.01.7-0.4-0.72.01.90.8-0.52.3-2.3-1.82.5-1.4-0.32.1
Bone: marrow area1.94.211.42.41.8-3.3-0.3-1.10.1-0.3-3.43.0-0.21.43.1-2.51.4-0.9-1.71.2-2.5-2.51.9
Bone: maximum diameter2.24.012.52.72.0-3.5-0.6-1.1-0.2-0.4-3.52.9-0.21.23.0-2.21.3-0.8-1.90.7-2.2-2.31.7
Bone: maximum force0.20.31.10.70.5-1.10.10.10.10.2-1.00.70.60.60.8-0.30.6-0.5-0.50.2-0.5-0.50.4
Bone: maximum moment0.10.20.60.40.1-0.70.20.40.20.4-0.80.30.70.60.6-0.10.6-0.7-0.60.3-0.4-0.20.5
Mean time between licks in bursts0.91.22.7-1.4-1.40.81.41.51.61.50.3-0.91.41.3-0.10.31.4-1.4-0.21.3-0.3-0.20.7
Mean num. licks in bursts0.70.84.1-0.10.20.7-0.5-0.1-0.8-0.20.8-1.1-0.2-1.0-1.31.0-1.10.60.5-0.71.32.0-1.0
Cd content in liver0.50.62.20.40.8-0.30.4-0.6-0.4-0.40.20.4-0.3-0.3-0.40.6-0.90.71.4-1.40.9-0.4-1.5
Co content in liver1.41.74.8-0.80.10.71.60.80.61.20.8-1.21.20.5-1.72.2-0.6-0.42.1-1.02.01.2-2.0
Cu content in liver0.60.82.0-0.6-0.10.80.70.60.30.60.8-1.20.80.0-1.41.4-0.4-0.11.2-0.51.41.2-1.1
Fe content in liver1.51.84.51.0-0.1-0.9-1.6-1.1-1.0-1.6-0.71.8-1.6-0.81.8-2.10.00.9-1.70.7-1.8-1.61.6
K content in liver0.30.30.60.70.5-0.3-0.7-0.7-0.8-0.8-0.10.4-0.7-0.70.0-0.1-0.60.70.1-0.60.20.1-0.3
Mg content in liver0.60.61.91.31.4-1.1-0.6-1.0-0.9-0.8-0.70.9-0.6-0.50.2-0.2-0.70.70.5-1.10.2-0.2-0.7
Mn content in liver1.61.84.3-1.0-1.40.50.91.71.71.5-0.5-0.81.71.60.5-0.32.1-1.9-1.51.7-1.1-0.41.6
Na content in liver0.80.92.5-0.0-0.7-0.40.00.40.50.1-0.60.90.20.71.4-1.21.1-0.6-1.31.2-1.5-1.21.6
Rb content in liver2.02.54.82.11.9-1.5-1.7-2.1-2.2-2.1-0.61.6-2.1-1.70.5-0.7-1.81.90.4-1.90.2-0.2-0.9
Se content in liver0.50.72.3-1.3-1.51.20.41.00.80.70.7-0.90.60.4-0.20.10.8-0.7-0.61.2-0.30.20.9
Sr content in liver1.00.92.4-0.6-0.6-0.21.51.11.41.3-0.50.31.31.60.60.01.2-1.30.01.1-0.5-0.90.6
Zn content in liver0.60.61.4-0.7-0.20.71.00.80.81.00.5-1.11.00.6-1.01.20.2-0.60.8-0.21.00.7-0.8
Bone: minimum diameter0.20.31.1-0.0-0.2-0.30.40.70.60.8-0.7-0.21.00.90.20.00.8-1.0-0.60.4-0.30.00.4
Time in familiar zone, hab. session 11.21.22.40.30.2-1.20.80.31.00.7-1.21.10.61.51.6-0.91.4-1.2-0.91.2-1.3-1.51.2
Time in novel zone, hab. session 12.02.04.10.40.90.7-1.4-1.1-1.6-1.20.9-1.1-1.1-2.0-1.70.9-1.91.71.0-2.01.61.8-1.7
Total zone transitions, hab. session 10.81.24.4-1.6-1.21.51.10.90.40.42.1-0.70.2-0.1-1.21.5-0.80.41.6-0.51.30.3-1.1
Total locomotion distance, hab. session 11.42.07.5-1.6-1.01.80.80.5-0.1-0.12.7-1.0-0.2-0.8-1.81.8-1.51.02.1-1.31.80.9-1.7
Locomotion velocity, hab. session 10.81.14.8-1.5-1.21.51.00.80.30.32.2-0.70.1-0.3-1.21.4-0.80.41.5-0.61.10.5-1.0
Time in familiar zone, hab. session 20.70.71.61.11.1-0.7-1.3-1.3-1.1-1.1-0.50.6-1.0-0.90.4-0.7-0.50.9-0.3-0.8-0.3-0.3-0.1
Time in novel zone, hab. session 20.10.10.4-0.3-0.50.20.20.50.40.4-0.1-0.30.40.30.0-0.00.4-0.5-0.40.6-0.20.30.5
Total zone transitions, hab. session 20.91.25.0-1.2-0.70.81.70.80.60.61.6-0.20.50.3-1.11.7-0.80.12.2-0.21.50.6-1.2
Total locomotion distance, hab. session 21.52.06.3-1.8-1.11.32.31.31.11.11.9-0.71.00.7-1.42.2-0.6-0.22.5-0.21.70.7-1.4
Locomotion velocity, hab. session 21.92.56.8-2.2-1.61.62.61.81.61.62.0-1.01.41.1-1.42.2-0.1-0.72.20.31.60.7-1.0
Novel to familiar place preference ratio0.10.10.30.40.5-0.50.3-0.10.20.2-0.40.30.20.40.2-0.10.2-0.20.20.0-0.0-0.3-0.1
Novelty place preference0.20.20.90.70.8-0.90.2-0.30.10.2-0.80.50.20.50.5-0.20.3-0.30.00.0-0.2-0.5-0.0
Time in novel zone, NPP test0.50.51.91.31.4-1.4-0.5-0.9-0.4-0.4-1.20.9-0.30.10.7-0.60.00.1-0.2-0.2-0.4-0.5-0.0
Total zone transitions, NPP test0.30.41.9-0.20.10.10.5-0.2-0.3-0.30.90.4-0.4-0.3-0.50.7-1.00.71.4-0.80.80.0-0.9
Total locomotion distance, NPP test0.40.63.3-0.8-0.40.41.30.40.40.31.10.10.30.2-0.61.1-0.60.21.8-0.61.0-0.2-1.0
Locomotion velocity, NPP test0.71.03.1-1.5-1.21.01.71.00.90.71.5-0.10.60.5-0.71.2-0.3-0.11.8-0.20.9-0.3-0.8
Intraocular pressure1.21.63.51.11.5-0.4-1.2-1.5-1.7-1.40.20.1-1.6-1.6-0.80.4-1.91.60.9-1.81.11.0-1.4
Delta distance traveled before/after self-admin0.20.21.30.81.1-0.80.0-0.5-0.1-0.0-0.80.10.20.1-0.10.3-0.1-0.00.3-0.60.40.5-0.4
Delta ambulatory time before/after self-admin0.20.21.10.70.9-0.7-0.1-0.30.10.1-1.10.00.20.20.10.00.3-0.3-0.2-0.20.00.30.0
Parametrial fat weight0.10.10.5-0.3-0.00.40.2-0.0-0.2-0.20.7-0.2-0.1-0.3-0.50.3-0.40.30.6-0.40.50.3-0.7
Pavlov. Cond. lever latency2.73.48.70.70.90.8-2.6-1.7-2.6-2.01.2-1.1-2.3-3.0-1.70.6-2.52.30.2-1.91.52.8-1.3
Pavlov. Cond. magazine entry latency4.05.213.2-2.2-2.20.83.63.13.53.20.2-0.73.53.30.20.92.6-3.00.52.1-0.3-1.50.7
Pavlov. Cond. change in total contacts2.62.88.5-1.5-1.40.32.92.22.62.4-0.0-0.32.72.60.10.81.8-2.20.71.3-0.1-1.10.2
Pavlov. Cond. index score3.64.511.9-1.8-1.90.33.52.73.32.8-0.2-0.03.13.30.70.52.6-2.80.42.1-0.7-2.00.9
Pavlov. Cond. latency score3.03.89.8-1.6-1.60.13.12.43.02.5-0.30.12.83.00.80.32.4-2.50.32.0-0.8-2.00.9
Pavlov. Cond. lever contacts2.12.56.5-0.7-0.8-0.52.41.62.31.9-0.80.62.22.51.1-0.22.1-2.00.11.5-1.0-2.20.9
Pavlov. Cond. magazine entry number2.63.38.62.02.0-0.9-2.9-2.5-2.8-2.5-0.40.6-2.7-2.5-0.0-0.8-1.92.3-0.6-1.50.21.2-0.5
Pavlov. Cond. intertrial magazine entries3.34.08.81.92.0-1.0-2.4-2.7-2.9-2.90.21.6-3.0-2.60.1-0.6-2.72.90.8-2.20.50.4-1.2
Pavlov. Cond. lever-magazine prob. diff.3.94.812.7-1.8-1.90.23.62.73.42.9-0.30.03.23.40.80.42.7-2.90.42.2-0.8-2.11.0
Pavlov. Cond. response bias2.32.88.1-1.5-1.40.32.92.22.62.3-0.0-0.22.52.60.30.61.9-2.10.71.5-0.3-1.40.4
Pavlov. Cond. lever latency1.52.04.9-2.1-1.72.21.11.50.81.02.1-2.10.80.0-1.91.9-0.3-0.21.0-0.31.41.4-0.9
Pavlov. Cond. magazine entry latency1.11.23.4-1.2-1.80.90.21.11.00.60.4-0.30.70.60.7-0.81.5-0.9-1.51.8-1.3-0.91.7
Pavlov. Cond. change in total contacts0.30.51.21.11.0-1.0-0.6-0.9-0.5-0.6-1.00.9-0.5-0.20.8-0.90.00.3-0.30.0-0.5-0.60.3
Pavlov. Cond. index score0.91.12.60.80.3-1.1-0.4-0.40.1-0.3-1.31.3-0.10.51.6-1.61.0-0.4-1.31.2-1.6-1.51.4
Pavlov. Cond. latency score1.31.63.91.00.3-1.3-0.7-0.50.1-0.4-1.61.5-0.20.51.9-2.01.2-0.4-1.71.4-2.0-1.61.7
Pavlov. Cond. lever contacts1.41.94.81.91.4-2.2-0.8-1.1-0.4-0.7-2.22.0-0.50.42.0-1.90.8-0.2-1.10.7-1.6-1.61.1
Pavlov. Cond. magazine entry number0.60.72.30.10.70.10.4-0.1-0.30.20.4-0.50.1-0.2-1.11.3-1.00.31.3-1.31.41.2-1.5
Pavlov. Cond. intertrial magazine entries0.20.31.2-0.30.2-0.11.10.50.70.9-0.2-0.20.70.9-0.20.70.3-0.70.60.10.40.3-0.3
Pavlov. Cond. lever-magazine prob. diff.0.81.02.40.5-0.0-0.9-0.1-0.00.40.0-1.21.10.20.71.5-1.41.2-0.7-1.21.4-1.6-1.41.5
Pavlov. Cond. response bias0.50.71.80.80.4-1.1-0.2-0.40.1-0.3-1.11.3-0.10.41.4-1.30.7-0.3-0.80.8-1.2-1.30.9
Time in closed arm before self-admin0.50.51.60.30.3-0.80.50.20.60.3-0.80.80.51.01.0-0.50.9-0.7-0.60.8-0.8-1.30.8
Time in closed arm after self-admin0.50.51.0-0.8-0.50.61.00.90.91.00.3-0.91.00.7-0.70.80.4-0.80.60.30.60.6-0.2
Time in open arm before self-admin0.40.41.40.80.9-1.10.2-0.30.20.3-1.20.60.40.70.7-0.60.6-0.5-0.40.3-0.6-0.40.7
Time in open arm after self-admin1.51.74.71.0-0.1-0.7-1.8-0.9-0.9-1.3-0.71.2-1.3-0.71.6-2.10.30.6-2.20.8-1.9-1.41.6
Bone: periosteal estimation1.22.57.52.01.4-2.6-0.6-0.8-0.2-0.4-2.72.2-0.10.92.4-1.91.0-0.6-1.60.6-1.8-1.81.4
Bone: periosteal perimeter0.91.43.21.50.9-1.7-0.9-0.8-0.5-0.7-1.81.7-0.60.21.8-1.60.5-0.1-1.50.4-1.5-1.31.2
Bone: post-yield work1.52.16.02.01.7-2.4-0.7-1.3-0.6-0.9-2.22.4-0.70.42.1-1.80.40.1-0.80.1-1.5-1.80.9
Progressive ratio test 1 active lever presses0.91.02.4-0.9-0.90.41.21.21.51.5-0.3-0.81.41.4-0.00.31.3-1.4-0.41.3-0.2-0.00.6
Progressive ratio test 1 breakpoint1.21.22.9-1.0-0.90.41.31.41.61.7-0.4-0.81.61.60.10.31.5-1.6-0.51.5-0.3-0.20.7
Progressive ratio test 1 inactive lever presses0.80.92.3-1.3-1.30.81.11.21.31.50.2-0.91.11.1-0.30.51.0-1.1-0.20.9-0.10.20.4
Progressive ratio test 2 active lever presses0.91.02.3-1.2-1.20.61.31.31.51.5-0.1-0.71.31.3-0.10.41.1-1.3-0.01.1-0.1-0.10.5
Progressive ratio test 2 breakpoint0.80.82.0-1.0-1.10.41.21.21.41.3-0.2-0.51.11.20.10.21.1-1.2-0.21.2-0.3-0.30.6
Progressive ratio test 2 inactive lever presses1.71.94.5-1.9-2.11.51.31.82.01.80.4-1.51.61.3-0.30.41.5-1.6-0.61.6-0.40.00.9
Incentive Sensitization - Responses1.01.02.3-1.2-1.20.71.41.41.51.50.0-0.71.41.2-0.20.61.0-1.30.30.9-0.0-0.10.2
Incentive Sensitization - Breakpoint1.01.02.3-1.3-1.30.81.51.41.41.50.3-0.91.31.1-0.50.80.7-1.20.70.70.30.2-0.1
Sum of active levers in priming session hrs 5-60.80.71.81.21.0-0.8-1.3-1.2-0.9-1.2-0.80.7-1.0-0.80.7-1.1-0.30.7-0.8-0.3-0.7-0.40.3
Progressive ratio0.60.72.40.10.5-0.71.50.51.21.2-0.80.11.31.40.00.60.7-1.31.10.30.30.1-0.2
Food seeking constrained by brief footshock3.44.111.43.43.4-3.0-2.0-2.9-2.2-2.3-2.02.5-2.1-1.21.4-1.6-1.41.5-0.3-1.5-0.6-0.8-0.2
Seeking ratio, punishment vs. effort2.22.75.91.91.7-1.2-2.4-2.2-2.4-2.4-0.41.5-2.4-2.00.8-1.4-1.62.2-0.8-1.3-0.5-0.6-0.2
Retroperitoneal fat weight1.34.211.3-1.8-0.61.82.11.20.71.42.1-2.11.00.1-2.93.2-1.4-0.03.4-1.63.02.4-2.9
Reaction time number correct0.50.71.50.80.4-0.7-0.9-0.9-0.7-1.2-0.31.2-0.9-0.61.0-1.2-0.00.7-0.60.1-0.9-1.10.6
Reaction time mean minus median0.60.82.3-1.3-1.11.50.30.80.50.61.3-1.50.3-0.2-1.21.0-0.2-0.00.4-0.20.81.1-0.5
Reaction time mean minus median AUC0.30.41.4-1.0-1.11.2-0.10.50.30.31.0-1.10.1-0.3-0.70.40.00.0-0.10.10.20.60.0
Reaction time num false alarms0.30.41.9-0.8-0.81.1-0.30.2-0.4-0.31.4-0.7-0.3-0.7-0.70.4-0.60.50.0-0.50.40.6-0.4
Reaction time num false alarms AUC0.30.51.9-0.7-0.91.1-0.50.1-0.5-0.51.4-0.6-0.5-1.0-0.70.3-0.70.60.0-0.50.30.6-0.3
Reaction time trials correct on left0.50.71.50.80.4-0.7-0.9-0.9-0.7-1.2-0.31.2-0.9-0.61.0-1.2-0.00.7-0.60.1-0.9-1.10.6
Reaction time trials on left0.50.71.40.70.3-0.6-1.0-0.9-0.8-1.2-0.21.2-0.9-0.70.9-1.2-0.10.8-0.60.1-0.9-1.10.6
Reaction time mean0.60.82.3-1.5-1.51.40.61.30.91.00.9-1.40.90.4-0.70.60.7-0.6-0.40.40.10.40.1
Reaction time mean AUC0.40.51.6-1.2-1.31.10.31.00.60.70.7-1.10.60.2-0.50.30.5-0.4-0.50.3-0.00.20.1
Median of all reaction times0.70.92.7-1.6-1.61.40.71.51.01.10.9-1.31.10.6-0.50.50.9-0.8-0.50.6-0.00.20.2
Reaction time omissions0.60.83.8-1.4-1.51.5-0.10.5-0.2-0.12.0-0.8-0.4-0.7-0.90.7-0.80.60.4-0.50.60.6-0.4
Reaction time false alarm rate0.50.72.1-1.0-0.91.4-0.10.4-0.20.01.4-1.3-0.1-0.7-1.30.9-0.80.40.4-0.70.91.3-0.7
Reaction time premature initiation rate0.40.61.40.51.0-0.3-0.3-0.7-0.7-0.50.30.1-0.6-0.7-0.60.7-1.20.81.0-1.21.00.7-1.1
Reaction time premature initiations0.50.71.50.91.1-0.6-0.8-1.1-1.1-1.10.10.6-1.1-1.0-0.10.1-1.21.10.7-1.10.50.2-0.7
Std. dev. reaction times0.60.82.9-1.5-1.51.70.10.90.40.51.5-1.50.2-0.3-1.10.8-0.20.00.1-0.20.60.8-0.3
Reaction time trials completed0.50.71.40.70.3-0.6-1.0-0.9-0.8-1.2-0.21.2-0.9-0.70.9-1.2-0.10.8-0.60.1-0.9-1.10.6
Reaction time trials AUC0.60.81.90.90.4-0.7-1.1-1.0-0.8-1.3-0.41.3-1.0-0.61.1-1.4-0.00.8-0.70.1-1.0-1.20.7
Run reversals in cocaine runway, females0.30.31.3-0.5-0.20.9-0.10.20.00.10.4-1.10.2-0.4-0.90.5-0.20.20.1-0.40.60.5-0.5
Run reversals in cocaine runway, males0.70.61.91.11.1-1.2-0.5-1.0-0.9-0.9-0.61.4-0.9-0.40.6-0.4-0.80.80.5-0.7-0.0-0.6-0.4
Latency to leave start box in cocaine runway0.50.61.70.0-0.4-0.30.10.20.60.2-0.50.60.20.61.0-1.01.1-0.5-0.91.1-1.1-0.91.3
Latency to leave start box in cocaine runway, F0.10.10.40.00.0-0.40.50.20.50.3-0.30.40.30.60.5-0.10.6-0.4-0.10.5-0.3-0.40.4
Latency to leave start box in cocaine runway, M0.30.30.9-0.6-1.00.60.20.50.60.20.3-0.20.40.30.3-0.50.7-0.3-0.50.8-0.6-0.70.9
Std. dev. time between licks in bursts0.91.02.9-0.2-0.4-0.61.10.51.30.7-0.81.00.81.51.2-0.71.3-1.0-0.31.2-1.2-1.71.1
Total sessions with >9 infusions1.61.83.9-1.2-1.50.21.21.61.61.7-0.4-0.21.51.80.8-0.21.9-1.7-1.12.0-1.0-0.71.4
Short access day 1 total inactive lever presses0.10.20.7-0.3-0.10.30.20.20.10.50.1-0.70.30.0-0.60.5-0.1-0.10.4-0.20.50.8-0.4
Short access day 10 total inactive lever presses0.20.20.50.50.3-0.1-0.7-0.6-0.6-0.70.10.2-0.7-0.7-0.0-0.2-0.60.70.0-0.5-0.00.1-0.0
Short access day 1 total infusions1.92.04.2-1.7-1.91.01.72.02.12.00.1-1.01.91.70.00.51.8-1.8-0.41.6-0.4-0.20.9
Short access day 10 total infusions2.52.86.3-1.8-2.51.11.02.01.91.9-0.1-0.91.61.70.7-0.52.3-2.0-1.92.5-1.5-0.62.1
Short access total infusions2.93.39.4-2.8-3.12.21.62.62.22.31.0-2.02.01.5-0.60.71.8-1.8-0.61.9-0.20.41.0
Short access day 1 locomotion0.50.51.6-0.5-0.3-0.21.10.80.91.1-0.30.11.11.30.40.10.9-0.9-0.10.7-0.2-0.90.2
Short access day 10 total locomotion0.10.10.4-0.1-0.2-0.20.30.40.40.4-0.20.20.40.60.5-0.00.6-0.5-0.50.5-0.3-0.40.4
Short access total locomotion1.81.94.3-1.7-1.80.91.62.01.82.10.1-1.11.91.7-0.00.51.7-1.8-0.51.5-0.3-0.40.6
One hour access (0.3 mA shock)0.70.81.9-1.2-1.41.00.91.21.21.10.3-0.90.90.9-0.20.40.8-1.0-0.41.1-0.20.40.7
Compulsive drug intake0.60.63.40.50.0-0.2-1.2-0.2-0.4-0.5-0.50.0-0.3-0.30.7-1.10.6-0.2-1.80.8-1.1-0.01.2
One hour access (shock baseline)1.51.74.0-1.6-1.70.71.91.82.01.80.1-0.51.71.80.20.41.5-1.6-0.11.5-0.4-0.60.9
Social response proportion0.30.31.3-0.5-0.80.9-0.20.60.10.20.4-1.10.4-0.2-0.60.30.2-0.3-0.80.40.10.90.2
Social responses0.60.71.9-0.7-0.70.31.21.21.31.1-0.2-0.51.41.20.00.31.1-1.3-0.21.3-0.2-0.10.6
Social time0.10.10.50.3-0.2-0.1-0.5-0.1-0.2-0.4-0.40.2-0.1-0.20.3-0.60.20.1-0.70.5-0.6-0.20.6
Soleus weight2.78.027.74.54.6-5.3-0.9-3.2-1.6-1.8-4.24.8-1.70.43.2-2.3-0.50.80.1-1.3-1.4-3.1-0.2
Bone: stiffness0.40.61.40.80.8-0.6-0.9-1.0-1.2-1.10.10.7-0.9-0.90.1-0.2-0.91.10.1-1.10.1-0.0-0.5
Tibialis anterior weight2.17.219.94.33.7-4.5-2.1-3.3-2.1-2.4-3.64.2-2.1-0.43.1-2.8-0.61.2-1.1-0.9-1.8-2.60.5
Time to tail flick, vehicle, before self-admin0.80.81.81.10.6-1.0-1.1-1.2-0.8-1.0-0.81.3-1.2-0.71.0-1.4-0.30.7-0.5-0.2-1.0-0.60.6
Time to tail flick, vehicle, after self-admin2.32.55.71.50.9-1.8-1.0-0.9-0.3-0.7-1.91.9-0.50.62.4-2.31.2-0.5-2.41.2-2.3-1.92.1
Time to tail flick, test, before self-admin0.20.20.8-0.20.3-0.00.90.30.20.40.3-0.10.50.4-0.50.9-0.2-0.00.9-0.30.90.3-0.6
Time to tail flick, test, after self-admin0.30.41.40.91.2-1.20.1-0.7-0.2-0.3-0.71.0-0.10.40.7-0.50.00.00.0-0.2-0.3-0.70.1
Delta time to tail flick, vehicle, before/after SA0.50.41.00.70.6-0.9-0.2-0.3-0.1-0.2-0.90.80.00.41.0-0.90.6-0.3-0.90.6-0.8-1.00.8
Delta time to tail flick, test, before/after SA1.21.13.11.20.6-1.2-1.0-0.8-0.3-0.6-1.41.1-0.50.11.5-1.80.6-0.2-1.40.6-1.6-1.11.3
Tibia length0.92.77.40.0-0.2-1.01.51.62.02.2-2.2-0.22.42.61.0-0.12.4-2.7-1.11.9-0.9-0.21.3
Ambulatory time before self-admin0.60.61.6-0.1-0.5-0.40.40.50.60.3-0.30.80.40.91.1-0.81.0-0.8-0.91.2-1.1-0.91.3
Ambulatory time after self-admin1.21.33.21.51.1-1.8-0.6-0.8-0.2-0.4-1.81.5-0.20.51.7-1.50.9-0.4-1.40.6-1.5-0.81.4
Bone: tissue strength0.20.20.7-0.1-0.10.6-0.7-0.2-0.6-0.50.7-0.6-0.4-0.8-0.50.2-0.50.5-0.2-0.30.30.8-0.1
Total heroin consumption1.01.23.51.81.8-1.9-0.9-1.4-0.8-0.9-1.51.6-0.9-0.21.2-1.1-0.10.3-0.4-0.2-0.8-0.50.5
Bone: trabecular number0.50.81.9-0.6-1.10.00.70.71.00.5-0.00.60.60.91.0-0.71.0-0.8-0.81.1-1.1-1.41.3
Bone: trabecular spacing1.62.15.1-1.5-0.81.90.70.70.10.62.0-2.00.3-0.6-2.32.1-1.00.31.8-0.62.02.2-1.6
Bone: trabecular thickness0.10.10.40.30.2-0.2-0.30.1-0.10.1-0.4-0.30.30.0-0.00.10.2-0.3-0.6-0.0-0.00.40.1
Bone: trabecular tissue density0.50.73.10.10.60.4-0.6-0.3-0.7-0.20.5-1.0-0.4-0.8-1.11.0-0.90.50.4-0.91.21.8-1.0
Water consumed over 24 hours0.91.14.71.61.6-1.9-0.3-0.8-0.1-0.1-2.21.30.00.61.4-1.10.7-0.5-0.70.6-0.9-0.70.7
Number of responses in last shaping day3.73.89.00.1-0.1-1.31.61.22.21.9-2.10.82.12.92.0-1.13.0-2.7-1.82.6-2.0-2.22.1