Gnal

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	Gnal	0.17	0.07	2.1e-14	0.11	0.12	0.12	0.11	4.1e-12	5.4e-13	8.8e-13	2.2e-12
2	PL	gene expression	Gnal	0.07	0.04	1.8e-06	0.05	0.06	0.06	0.06	5.1e-06	3.4e-07	7.5e-07	7.6e-07
3	Adipose	mRNA stability	Gnal	0.16	0.08	5.5e-10	0.07	0.08	0.07	0.08	7.8e-08	1.7e-09	1.6e-08	2.4e-09
4	IL	gene expression	Gnal	0.25	0.13	7.5e-04	0.07	0.11	0.07	0.1	9.8e-03	1.1e-03	9.0e-03	2.4e-03
5	NAcc	gene expression	Gnal	0.04	0.02	3.5e-06	0.05	0.04	0.04	0.04	8.2e-08	2.4e-06	6.8e-07	4.0e-07
6	NAcc	mRNA stability	Gnal	0.03	0.02	5.8e-04	0.03	0.02	0.02	0.02	3.9e-05	2.8e-04	1.7e-04	1.3e-04
7	Brain	mRNA stability	Gnal	0.18	0.08	3.5e-08	0.09	0.09	0.08	0.08	2.5e-08	1.3e-08	3.6e-08	4.3e-08
8	Brain	gene expression	Gnal	0.36	0.11	0.0e+00	0.21	0.25	0.25	0.24	1.9e-19	8.3e-23	1.3e-23	7.0e-22
9	Adipose	gene expression	Gnal	0.3	0.1	0.0e+00	0.2	0.23	0.23	0.23	9.5e-22	2.1e-25	2.9e-25	3.2e-25
10	PL	mRNA stability	Gnal	0.06	0.04	3.4e-05	0.03	0.04	0.04	0.04	8.9e-04	1.1e-05	1.2e-05	1.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.7	1.3	2.0	1.2	-1.4	-1.4	-1.4	-1.0	-1.1	-0.2	-1.4	-0.9	-0.5
Area under the delay curve	0.8	1.0	3.4	-1.9	1.2	1.0	0.9	1.3	0.9	-0.0	0.6	0.2	-0.2
BMI with tail	0.0	0.1	0.5	-0.2	0.3	0.2	0.3	0.2	0.3	0.7	0.4	0.4	0.3
BMI without tail	0.3	0.9	2.1	-1.4	1.1	1.1	1.1	1.0	0.9	0.3	0.8	0.7	0.5
Body weight	0.1	0.3	1.3	-0.0	0.0	-0.2	0.2	0.2	0.4	1.1	0.5	0.6	0.6
Weight adjusted by age	0.3	0.4	1.5	-0.4	-0.3	-0.0	-0.2	-0.4	-0.8	-1.2	-0.8	-0.8	-0.7
Bone surface	0.9	1.6	2.9	1.7	-1.6	-1.5	-1.6	-1.1	-1.1	-0.3	-1.5	-0.9	-0.4
Bone volume	0.3	0.5	1.0	0.7	-0.8	-1.0	-0.9	-0.5	-0.6	0.3	-0.8	-0.5	-0.2
Breakpoint value in progressive ratio session	0.8	0.9	1.5	-0.5	0.9	0.9	1.0	1.0	0.7	1.0	1.2	1.2	1.2
Number of licking bursts	0.9	1.5	2.2	1.0	-1.3	-1.5	-1.5	-1.2	-1.1	-0.5	-1.3	-1.3	-1.3
Context. condit. distance diff. score	0.2	0.3	1.5	-0.0	-0.0	-0.3	0.2	0.3	0.0	1.2	0.8	0.5	0.5
Locomotion velocity, session 1	4.5	4.8	10.1	3.2	-2.7	-2.1	-2.4	-2.1	-2.0	-1.6	-2.2	-1.7	-1.1
Locomotion distance, session 1	2.6	3.2	9.6	3.1	-2.4	-2.3	-2.0	-1.7	-1.5	0.0	-1.2	-0.9	-0.4
Locomotion velocity, session 2	1.0	1.2	1.9	1.3	-1.1	-0.8	-0.9	-1.4	-1.1	-1.2	-1.0	-1.0	-1.0
Locomotion distance, session 2	0.9	1.2	3.6	1.9	-1.5	-1.5	-1.2	-1.0	-0.9	0.6	-0.5	-0.3	0.1
Locomotion velocity, session 3	0.9	1.0	2.9	1.7	-1.2	-0.8	-1.1	-0.8	-0.9	-0.7	-0.8	-0.7	-0.4
Locomotion distance, session 3	0.9	1.0	1.6	0.9	-1.1	-1.1	-1.3	-0.9	-1.1	-0.6	-0.8	-1.1	-1.0
Stereotopy head waving bouts, day 3	0.0	0.1	0.2	-0.5	0.0	-0.0	0.1	-0.2	-0.2	-0.4	-0.3	-0.2	-0.1
Stereotopy head waving duration, day 3	0.1	0.2	0.4	-0.2	0.2	0.2	0.5	0.0	0.4	0.5	0.3	0.6	0.6
Locomotion velocity, session 7	0.2	0.2	0.5	0.7	-0.1	-0.1	0.1	0.2	0.2	0.7	0.5	0.4	0.4
Locomotion distance, session 7	0.3	0.3	0.8	0.1	0.3	0.5	0.4	0.5	0.7	0.6	0.6	0.7	0.9
Stereotopy head waving bouts, day 7	2.2	2.5	4.2	0.4	-1.2	-1.2	-1.3	-1.8	-1.7	-1.9	-1.7	-1.9	-2.0
Stereotopy head waving duration, day 7	1.5	1.9	2.9	0.5	-1.1	-1.0	-1.2	-1.5	-1.5	-1.7	-1.5	-1.6	-1.7
Locomotion velocity, session 8	4.1	4.9	9.7	3.1	-2.9	-2.8	-2.6	-2.2	-2.4	-0.4	-1.8	-1.5	-0.8
Locomotion distance, session 8	0.5	0.7	2.4	1.1	-0.9	-1.2	-0.6	-0.3	-0.6	1.6	0.5	0.3	0.5
Degree of sensitization distance	1.7	1.7	2.7	-0.9	1.2	1.4	1.4	1.4	1.4	0.9	1.2	1.5	1.6
Degree of sensitization stereotypy	1.4	1.5	3.2	0.1	-0.8	-0.9	-1.0	-1.3	-1.3	-1.4	-1.2	-1.5	-1.8
Conditioned locomotion	1.4	1.6	4.7	-2.2	1.7	1.6	1.5	1.1	1.0	-0.0	0.8	0.6	0.2
Cocaine response after cond. corrected	1.6	2.0	7.1	-2.7	1.7	2.0	1.4	0.7	1.0	-1.4	0.3	-0.0	-0.3
Cocaine response after cond. not corrected	0.9	1.1	3.6	-1.9	1.3	1.4	1.3	0.4	0.9	-0.8	0.4	0.2	-0.1
Cocaine response before conditioning	0.7	0.8	3.3	1.8	-0.9	-1.1	-0.5	-0.4	-0.4	1.2	0.2	0.4	0.5
Saline control response	0.6	0.8	4.2	2.0	-1.1	-0.4	-0.8	-0.3	0.1	0.4	-0.5	0.4	1.2
Bone: connectivity density	0.8	1.2	1.9	1.1	-1.4	-1.3	-1.3	-1.1	-1.2	-0.7	-1.4	-1.0	-0.5
Bone: cortical apparent density	2.2	3.1	6.2	-0.6	-1.2	-1.8	-1.5	-1.9	-1.9	-1.4	-1.8	-2.2	-2.5
Bone: cortical area	0.2	0.2	1.1	-0.4	0.3	-0.4	0.2	0.1	0.1	1.0	0.7	0.1	-0.6
Bone: cortical porosity	0.2	0.2	0.3	0.3	-0.4	-0.5	-0.6	-0.4	-0.3	-0.0	-0.5	-0.4	-0.4
Bone: cortical porosity	0.0	0.0	0.1	-0.2	0.2	0.0	-0.1	0.2	0.1	0.3	-0.1	-0.0	-0.2
Bone: cortical thickness	0.6	1.0	3.7	-0.3	-0.4	-1.3	-0.7	-1.0	-1.1	-0.1	-0.5	-1.2	-1.9
Bone: cortical thickness	0.7	0.8	2.8	0.3	-0.8	-1.7	-0.9	-0.8	-1.0	0.6	-0.4	-0.8	-1.2
Bone: cortical tissue density	2.1	2.8	5.7	-0.7	-1.1	-1.7	-1.4	-1.9	-1.8	-1.3	-1.7	-2.1	-2.4
Condit. Reinf. active minus inactive responses	2.7	3.1	6.1	1.0	-1.7	-1.0	-1.6	-1.8	-1.8	-2.5	-2.3	-1.8	-1.3
Condit. Reinf. active-inactive response ratio	1.2	1.3	4.9	-0.0	-0.8	-0.1	-0.8	-0.9	-1.0	-2.2	-1.6	-1.3	-0.8
Condit. Reinf. active responses	1.7	2.1	4.8	1.2	-1.4	-0.7	-1.3	-1.4	-1.4	-2.2	-1.9	-1.4	-0.9
Condit. Reinf. inactive responses	0.2	0.2	0.5	0.7	0.1	0.1	0.4	0.4	0.5	0.6	0.5	0.6	0.5
Incentive salience index mean	3.6	4.4	7.9	1.4	-2.0	-1.4	-2.0	-2.1	-2.2	-2.8	-2.6	-2.3	-1.8
Condit. Reinf. lever presses	0.9	1.3	2.2	1.2	-1.2	-0.8	-1.0	-1.3	-1.1	-1.5	-1.4	-1.1	-0.8
Condit. Reinf. active minus inactive responses	0.4	0.5	1.9	1.4	-0.9	-0.9	-0.8	-0.6	-0.6	0.3	-0.4	-0.3	-0.4
Condit. Reinf. active-inactive response ratio	0.2	0.2	1.1	0.6	-0.1	-0.3	-0.0	0.4	0.2	1.1	0.5	0.4	0.4
Condit. Reinf. active responses	0.3	0.5	1.3	1.2	-0.8	-0.8	-0.7	-0.9	-0.6	0.1	-0.4	-0.3	-0.3
Condit. Reinf. inactive responses	0.4	0.5	1.5	1.0	-0.8	-0.6	-0.5	-1.2	-0.6	-0.5	-0.6	-0.4	-0.3
Condit. Reinf. lever presses	0.4	0.5	1.1	1.1	-0.8	-0.9	-1.0	-0.7	-0.6	0.4	-0.6	-0.4	-0.4
Condit. Reinf. lever reinforcers received	0.3	0.4	0.8	0.9	-0.7	-0.6	-0.6	-0.9	-0.6	-0.1	-0.5	-0.4	-0.5
Conditioned reinforcement - actives	0.3	0.4	1.3	0.0	-0.5	-0.3	-0.7	-0.1	-0.7	-1.1	-0.9	-0.8	-0.5
Conditioned reinforcement - inactives	0.0	0.1	0.2	0.2	0.2	0.2	-0.2	0.4	0.1	0.3	0.4	0.0	-0.1
Conditioned locomotion	0.1	0.1	0.6	-0.1	0.0	0.2	0.2	0.8	0.1	0.2	0.1	0.3	0.7
Patch foraging indifference point 0 sec	0.2	0.5	1.1	1.0	-0.9	-0.9	-0.9	-0.6	-0.5	0.1	-0.6	-0.4	-0.2
Patch foraging indifference point AUC	0.4	0.6	2.7	1.6	-0.9	-0.6	-0.5	-0.3	0.2	0.9	0.1	0.6	1.0
Delay disc. indifference point, 0s delay	1.3	1.4	8.4	-2.9	1.4	1.0	0.8	0.8	0.4	-0.5	0.1	-0.3	-0.8
Delay disc. indifference point, 16s delay	0.2	0.2	0.5	-0.6	0.6	0.5	0.3	0.7	0.3	0.3	0.3	0.2	0.1
Delay disc. indifference point, 2s delay	1.8	2.0	3.6	-0.9	1.4	1.1	1.4	1.9	1.5	1.6	1.8	1.4	1.0
Delay disc. indifference point, 24s delay	0.6	0.7	2.3	-1.0	0.3	0.3	-0.1	-0.2	-0.2	-1.5	-0.5	-1.0	-1.3
Delay disc. indifference point, 4s delay	0.1	0.1	0.5	-0.5	-0.1	-0.4	-0.2	0.0	-0.1	0.2	-0.2	-0.4	-0.7
Delay disc. indifference point, 8s delay	2.1	2.5	5.2	-2.3	2.0	1.8	1.8	2.0	1.6	0.1	1.3	0.9	0.5
Indifference point function ln k	0.0	0.1	0.3	-0.6	0.3	0.1	0.2	0.3	0.1	0.2	0.1	0.1	-0.0
Indifference point function log k	0.0	0.1	0.3	-0.6	0.3	0.1	0.2	0.3	0.1	0.2	0.1	0.1	-0.0
Patch foraging total patch changes 0 sec	0.3	0.5	1.8	1.3	-1.0	-0.8	-0.9	-0.4	-0.3	0.2	-0.5	-0.1	0.2
Patch foraging total patch changes 12 sec	0.5	0.6	1.8	0.7	-0.0	0.1	0.3	0.3	0.7	1.2	0.7	1.1	1.3
Patch foraging total patch changes 18 sec	0.5	0.7	2.6	1.6	-1.2	-1.0	-1.0	-0.8	-0.4	0.3	-0.6	-0.1	0.3
Patch foraging total patch changes 24 sec	0.9	1.5	4.7	2.2	-0.7	-0.4	-0.1	0.5	0.9	1.7	0.7	1.4	1.9
Patch foraging total patch changes 6 sec	0.4	0.6	2.9	1.7	-0.9	-0.7	-0.6	-0.3	0.0	0.7	-0.2	0.4	0.7
Patch foraging time to switch 0 sec	0.4	0.7	4.4	-2.1	1.1	0.5	0.8	0.3	0.0	-0.2	0.3	-0.3	-0.8
Patch foraging water rate 0 sec	0.3	0.6	3.3	1.8	-0.6	-0.3	-0.2	0.2	0.5	0.8	0.2	0.7	1.1
Patch foraging water rate 12 sec	0.7	1.4	6.0	2.5	-1.3	-0.9	-0.7	-0.2	-0.1	1.3	0.0	0.9	1.5
Patch foraging water rate 18 sec	1.5	2.4	6.4	2.5	-2.1	-1.7	-1.6	-1.5	-1.5	-0.6	-1.4	-0.8	-0.2
Patch foraging water rate 24 sec	0.6	0.9	3.6	1.9	-0.9	-0.6	-0.6	0.0	0.0	1.3	-0.2	0.7	1.3
Patch foraging water rate 6 sec	0.5	0.7	2.7	1.3	-0.4	0.0	0.0	0.3	0.5	1.0	0.3	1.0	1.6
Seeking ratio, delayed vs. immediate footshock	0.3	0.4	1.1	0.6	-0.0	-0.1	0.3	0.9	0.2	1.1	0.5	0.8	0.9
Distance traveled before self-admin	0.5	0.6	2.0	-1.4	1.0	1.0	0.7	0.2	1.2	-0.5	0.2	0.0	-0.3
Distance traveled after self-admin	0.1	0.1	0.3	-0.1	0.1	-0.2	-0.0	-0.3	-0.3	0.3	0.1	-0.2	-0.5
Extensor digitorum longus weight	0.0	0.1	0.3	0.5	-0.3	-0.2	-0.1	-0.4	-0.0	0.1	-0.1	0.1	0.3
Bone: elastic displacement	2.2	2.5	3.9	1.9	-2.0	-1.9	-1.9	-1.4	-1.7	-0.8	-1.6	-1.3	-1.0
Bone: elastic work	0.6	0.8	2.1	0.5	-1.0	-1.5	-1.0	-0.9	-1.0	0.1	-0.7	-0.8	-1.0
Bone: endosteal estimation	0.7	1.5	3.5	0.2	0.7	0.7	0.8	1.3	1.4	1.9	1.3	1.5	1.6
Bone: endosteal perimeter	1.0	2.0	3.1	-0.8	1.4	1.3	1.4	1.4	1.8	1.4	1.6	1.5	1.3
Epididymis fat weight	0.5	1.6	4.4	-2.1	1.6	1.3	1.2	1.7	1.0	0.7	0.9	0.8	0.7
Delta time in closed arm before/after self-admin	0.2	0.2	0.6	-0.3	0.4	0.1	0.4	0.5	-0.6	0.7	0.4	0.5	0.3
Delta time in open arm before/after self-admin	0.4	0.4	1.3	0.7	0.1	0.2	0.3	0.2	1.1	0.7	0.7	0.7	0.7
Diff in mean of infusions in LGA sessions	0.8	1.0	1.8	-0.8	1.1	1.3	1.1	1.3	0.5	0.3	1.0	1.0	1.0
Delay discount exponential model param	0.8	0.9	3.2	1.8	-1.2	-0.9	-0.9	-1.2	-0.8	0.0	-0.6	-0.2	0.2
Extinction: sum of active levers before priming	0.2	0.2	0.7	0.6	-0.3	-0.5	-0.3	0.1	-0.5	0.8	0.3	0.2	0.2
Active lever presses in extinction session 6	0.3	0.3	0.9	-0.4	0.4	0.2	0.4	0.4	0.9	0.6	0.5	0.5	0.4
Bone: final force	0.4	0.6	1.8	0.5	-0.5	-1.4	-0.7	-0.7	-0.4	1.1	-0.1	-0.4	-1.0
Bone: final moment	0.4	0.6	2.5	0.6	-0.4	-1.3	-0.5	-0.5	-0.2	1.6	0.2	-0.1	-0.6
Food consumed during 24 hour testing period	1.2	1.6	3.9	0.4	-1.0	-2.0	-1.6	-1.0	-1.3	0.5	-0.9	-1.4	-1.8
Glucose	1.6	2.4	7.4	-0.3	-0.5	-0.3	-1.1	-1.3	-1.1	-2.7	-1.8	-2.1	-2.2
Heart weight	0.2	0.4	0.6	0.3	-0.6	-0.7	-0.8	-0.6	-0.6	-0.4	-0.6	-0.7	-0.7
Delay discount hyperbolic model param	0.7	0.8	2.8	1.7	-1.1	-0.8	-0.8	-1.2	-0.9	-0.0	-0.6	-0.2	0.2
Intermittent access intake day 1-15 change	0.3	0.6	1.9	-0.9	0.3	0.3	-0.1	-0.1	-0.4	-1.4	-0.4	-0.9	-1.2
Intermittent access intake escalation	0.2	0.5	1.4	-1.1	0.4	0.3	0.1	-0.1	-0.3	-1.2	-0.2	-0.7	-1.1
Intermittent access intake escalation 2	0.5	0.6	1.9	-1.4	1.0	0.8	0.8	0.6	0.3	-0.4	0.5	-0.0	-0.5
Intermitt. access day 1 inactive lever presses	0.2	0.6	1.9	1.4	-0.4	-0.4	-0.1	0.4	0.2	1.2	0.9	0.8	1.0
Intermitt. access day 15 inactive lever presses	0.6	1.2	3.3	1.8	-1.3	-1.7	-1.3	-0.8	-0.9	0.7	-0.3	-0.6	-0.6
Intermitt. access escalation Index	0.3	0.4	0.9	0.1	0.8	0.8	0.7	0.3	0.9	0.2	0.9	0.5	0.1
Intermittent access day 1 total infusions	0.2	0.4	1.3	1.2	-0.8	-0.6	-0.7	-0.1	-0.3	0.6	-0.1	0.1	0.5
Intermittent access day 15 total infusions	0.0	0.1	0.1	0.1	-0.1	-0.0	-0.4	-0.1	-0.3	-0.3	-0.2	-0.3	-0.3
Intermittent access terminal intake (last 3 days)	0.0	0.1	0.2	-0.2	0.0	0.1	-0.2	-0.0	-0.3	-0.4	-0.2	-0.3	-0.3
Intermittent access total infusions	0.3	0.3	0.5	0.6	-0.6	-0.3	-0.7	-0.3	-0.5	-0.6	-0.6	-0.6	-0.5
Intermittent access day 1 locomotion	0.7	1.0	2.6	-0.1	0.6	1.0	0.7	1.1	0.9	1.0	0.8	1.2	1.6
Intermittent access day 15 total locomotion	0.5	1.0	1.8	-1.2	1.2	1.3	1.1	1.2	1.0	-0.1	0.7	0.7	0.6
Intermittent access total locomotion	0.3	0.3	0.7	-0.4	0.4	0.6	0.4	0.8	0.5	0.3	0.4	0.6	0.8
Intermittent access standard deviation	0.3	0.6	2.2	-0.5	-0.3	-0.2	-0.4	-0.2	-0.9	-1.5	-0.8	-1.1	-1.1
Left kidney weight	0.0	0.1	0.5	-0.7	-0.1	-0.4	-0.3	-0.1	-0.2	0.4	-0.2	-0.3	-0.3
Right kidney weight	0.1	0.3	2.4	-1.5	0.6	0.4	0.3	0.4	0.2	-0.0	-0.1	-0.0	-0.1
Cocaine induced anxiety	0.4	0.5	2.4	-1.5	0.6	0.1	0.2	-0.3	-0.2	-0.5	0.0	-0.7	-1.3
Post-drug Anxiety	0.3	0.4	1.8	-1.4	0.5	0.2	0.2	-0.1	-0.1	-0.5	-0.0	-0.6	-1.0
Baseline Anxiety	0.7	0.8	1.7	1.3	-1.2	-0.9	-1.1	-0.6	-0.8	-0.5	-1.0	-0.6	-0.0
Tail length	0.0	0.1	0.2	-0.4	-0.2	-0.4	-0.1	-0.1	-0.3	0.0	-0.2	-0.1	-0.2
Length with tail	0.1	0.5	1.6	0.8	-1.0	-1.3	-0.8	-0.4	-0.6	0.7	-0.4	-0.2	0.0
Length without tail	0.4	1.3	3.1	1.2	-1.3	-1.8	-1.5	-1.0	-1.1	0.5	-0.7	-0.8	-0.9
Times rat made contact with spout	1.2	1.4	6.3	1.4	-0.3	-0.6	-0.1	0.8	0.6	2.5	0.9	1.2	1.4
Lifetime Intake	0.0	0.1	0.3	0.6	-0.2	-0.1	-0.3	0.1	-0.1	0.1	-0.1	-0.0	0.2
Liver weight, left	0.9	1.4	4.8	2.2	-1.8	-1.8	-1.0	-0.5	-1.1	0.7	-0.3	0.0	0.5
Liver weight, right	0.1	0.2	0.4	-0.2	0.2	0.2	0.4	0.5	0.3	0.5	0.6	0.5	0.6
Locomotor activity	0.4	0.7	3.7	1.9	-0.9	-0.9	-0.6	-0.7	-0.6	0.2	-0.1	-0.0	-0.1
Locomotor testing distance	1.2	2.2	6.3	2.5	-1.9	-1.8	-1.4	-1.6	-1.5	-0.5	-1.0	-0.9	-0.7
Locomotor testing rearing	0.1	0.2	0.6	0.0	0.6	0.7	0.8	0.2	0.5	-0.2	0.4	0.5	0.2
Locomotion in novel chamber	1.1	1.4	4.1	1.2	-0.1	0.1	0.4	1.2	0.6	1.7	1.2	1.5	2.0
Locomotion in novel chamber post-restriction	0.5	0.9	3.4	1.8	-1.1	-0.4	-1.0	-0.8	-0.4	-1.1	-0.9	-0.5	-0.0
Fecal boli incidents, locomotor time 1	0.1	0.2	0.6	0.4	-0.6	-0.2	-0.6	-0.1	-0.0	-0.4	-0.8	-0.3	0.2
Change in fecal boli incidents, locomotor task	0.6	0.6	1.0	0.9	-0.7	-1.0	-0.9	-1.0	-0.4	-0.1	-0.4	-0.7	-0.9
Time >=10cm from walls, locomotor time 1	0.6	0.6	1.8	-1.2	0.7	0.6	0.5	0.8	1.4	0.6	0.4	0.5	0.3
Bouts of movement, locomotor time 1	1.9	2.1	4.1	-1.5	1.6	1.4	1.4	1.9	2.0	1.0	1.2	1.2	1.1
Total resting periods, locomotor time 1	1.4	1.6	2.7	-0.7	1.2	0.9	1.1	1.6	1.7	1.3	1.2	1.3	1.2
Rest time, locomotor task time 1	0.3	0.3	1.8	1.3	-0.5	-0.4	-0.5	-0.3	0.7	0.5	0.2	0.2	0.4
Distance moved, locomotor task time 1	0.0	0.1	0.5	-0.3	0.1	-0.0	0.2	-0.1	-0.7	0.1	0.0	0.0	-0.1
Vertical activity count, locomotor time 1	0.1	0.1	0.3	-0.4	0.4	0.3	0.5	0.3	0.0	0.4	0.4	0.5	0.4
Time >=10cm from walls, locomotor time 2	0.4	0.6	2.3	-0.5	0.6	0.6	0.4	0.9	1.5	0.9	0.4	0.7	0.6
Bouts of movement, locomotor time 2	0.9	1.5	3.1	-1.5	1.5	1.8	1.7	1.2	0.6	-0.6	0.7	0.8	0.8
Total resting periods, locomotor time 2	0.6	1.1	2.4	-1.4	1.3	1.6	1.4	1.0	0.7	-0.5	0.5	0.7	0.7
Rest time, locomotor task time 2	1.3	1.6	2.7	0.6	-1.2	-1.4	-1.6	-1.6	-0.8	-0.9	-1.2	-1.5	-1.5
Distance moved, locomotor task time 2	0.2	0.2	0.4	-0.3	0.5	0.5	0.6	0.5	0.3	0.2	0.4	0.5	0.3
Vertical activity count, locomotor time 2	0.8	1.0	1.8	-0.0	0.8	0.9	1.0	1.1	0.6	1.2	1.2	1.4	1.3
Light reinforcement 1	0.3	0.8	2.4	1.5	-0.6	-0.5	-0.3	-0.1	0.2	1.6	0.4	0.9	1.3
Light reinforcement 2	0.1	0.2	1.1	1.0	-0.4	-0.3	-0.4	-0.2	-0.2	0.2	-0.0	-0.0	0.0
Bone: marrow area	0.8	1.7	3.7	0.2	0.7	0.7	0.9	1.3	1.5	1.9	1.4	1.6	1.6
Bone: maximum diameter	1.2	2.2	3.5	-0.4	1.3	1.1	1.4	1.5	1.7	1.8	1.9	1.7	1.5
Bone: maximum force	0.2	0.3	1.4	-0.5	0.5	-0.4	0.2	0.2	0.3	1.2	0.6	0.1	-0.6
Bone: maximum moment	0.3	0.5	2.7	-0.4	0.6	-0.3	0.4	0.4	0.5	1.6	0.9	0.4	-0.2
Mean time between licks in bursts	0.0	0.0	0.1	-0.4	-0.1	-0.1	0.1	-0.2	-0.2	-0.4	-0.2	-0.1	-0.1
Mean num. licks in bursts	1.6	2.5	4.2	-0.2	1.1	1.1	1.4	1.7	1.4	2.0	1.8	2.0	2.1
Cd content in liver	1.8	2.0	5.3	-0.0	-0.8	-0.4	-1.3	-1.4	-1.0	-2.3	-1.8	-1.8	-1.7
Co content in liver	1.6	1.9	2.6	0.8	-1.3	-1.4	-1.6	-1.4	-1.2	-1.3	-1.5	-1.6	-1.6
Cu content in liver	0.1	0.1	0.4	0.2	0.2	0.5	0.3	0.4	0.1	-0.1	0.2	0.4	0.6
Fe content in liver	2.3	2.7	5.4	1.8	-2.1	-2.3	-2.1	-1.3	-2.0	-0.0	-1.4	-1.3	-1.0
K content in liver	0.1	0.1	0.2	0.2	0.1	0.2	0.2	0.3	0.4	-0.1	0.3	0.1	0.1
Mg content in liver	0.3	0.3	0.8	-0.1	0.4	0.2	0.6	0.7	0.6	0.6	0.9	0.5	0.3
Mn content in liver	1.2	1.3	3.3	1.3	-1.4	-1.2	-1.2	-0.7	-1.8	-0.7	-1.0	-0.8	-0.4
Na content in liver	0.3	0.4	1.6	1.3	-0.7	-0.8	-0.5	0.2	-0.4	0.6	-0.1	0.2	0.4
Rb content in liver	0.1	0.1	0.4	-0.3	-0.1	-0.4	-0.4	-0.2	-0.5	-0.2	-0.3	-0.5	-0.6
Se content in liver	0.6	0.7	1.3	-0.6	1.1	0.9	1.2	0.9	1.0	0.4	0.9	0.8	0.5
Sr content in liver	1.0	0.8	3.2	1.8	-1.1	-1.2	-0.9	-0.7	-0.7	0.8	-0.2	-0.1	-0.1
Zn content in liver	0.6	0.7	2.0	-0.0	0.5	0.5	0.7	0.9	1.4	0.9	0.7	1.0	1.1
Bone: minimum diameter	1.2	2.2	5.0	-1.0	1.6	0.9	1.4	1.4	1.6	2.2	1.9	1.5	0.8
Time in familiar zone, hab. session 1	0.1	0.1	0.3	-0.1	-0.3	-0.6	-0.3	-0.3	-0.5	0.5	-0.0	-0.1	-0.1
Time in novel zone, hab. session 1	0.9	0.9	1.5	-0.2	1.0	1.2	0.9	1.1	1.2	0.5	0.8	1.0	1.0
Total zone transitions, hab. session 1	3.7	5.2	9.4	3.1	-3.0	-2.8	-2.7	-2.4	-2.3	-0.4	-1.9	-1.6	-0.8
Total locomotion distance, hab. session 1	3.6	5.0	8.6	2.4	-2.9	-2.7	-2.7	-2.4	-2.4	-0.7	-2.3	-1.7	-0.9
Locomotion velocity, hab. session 1	4.0	5.6	8.7	2.2	-2.9	-2.8	-2.8	-2.6	-2.6	-1.0	-2.4	-2.1	-1.4
Time in familiar zone, hab. session 2	0.5	0.5	1.4	0.9	-0.6	-0.7	0.1	0.1	-0.2	1.2	0.4	0.8	1.1
Time in novel zone, hab. session 2	0.5	0.5	1.5	-1.1	0.6	0.7	0.1	-0.0	0.0	-1.2	-0.3	-0.8	-1.1
Total zone transitions, hab. session 2	1.9	2.4	7.7	2.8	-2.0	-2.2	-1.4	-0.9	-0.9	1.9	-0.1	0.3	0.8
Total locomotion distance, hab. session 2	1.0	1.3	3.7	1.9	-1.5	-1.6	-1.0	-0.7	-0.7	1.4	-0.1	0.2	0.7
Locomotion velocity, hab. session 2	1.0	1.3	3.9	2.0	-1.5	-1.6	-1.1	-0.8	-0.8	1.1	-0.2	0.1	0.6
Novel to familiar place preference ratio	2.2	2.4	3.0	-1.3	1.7	1.7	1.7	1.7	1.5	1.2	1.6	1.7	1.5
Novelty place preference	1.9	2.0	2.5	-1.3	1.5	1.5	1.6	1.5	1.3	1.1	1.5	1.5	1.2
Time in novel zone, NPP test	2.0	2.2	2.7	-1.3	1.6	1.6	1.6	1.6	1.4	1.1	1.5	1.6	1.4
Total zone transitions, NPP test	1.8	2.5	6.2	2.5	-2.1	-2.2	-1.7	-1.8	-1.4	0.5	-0.8	-0.6	-0.3
Total locomotion distance, NPP test	1.2	1.7	4.5	2.1	-1.8	-1.9	-1.4	-1.1	-1.0	0.9	-0.6	-0.2	0.4
Locomotion velocity, NPP test	1.4	2.0	4.4	2.1	-2.0	-2.0	-1.6	-1.4	-1.3	0.4	-0.9	-0.6	-0.1
Intraocular pressure	0.2	0.3	1.2	1.1	-0.8	-0.8	-0.4	-0.4	-0.6	0.5	0.1	0.1	0.1
Delta distance traveled before/after self-admin	0.3	0.3	0.9	0.7	-0.3	-0.4	-0.1	0.1	-0.7	1.0	0.4	0.4	0.4
Delta ambulatory time before/after self-admin	1.1	1.4	4.2	1.2	-1.3	-1.5	-1.3	-1.0	-2.0	0.3	-0.8	-0.7	-0.4
Parametrial fat weight	2.9	6.8	13.7	-3.7	3.2	2.3	2.9	2.7	2.4	2.1	2.7	2.0	1.0
Pavlov. Cond. lever latency	2.1	2.7	4.7	-1.1	1.5	1.1	1.5	1.7	1.7	2.2	1.7	1.8	1.6
Pavlov. Cond. magazine entry latency	0.9	1.2	2.9	0.9	-0.9	-0.6	-1.0	-0.9	-1.1	-1.7	-1.1	-1.3	-1.2
Pavlov. Cond. change in total contacts	0.8	0.8	1.9	0.4	-0.6	-0.4	-0.8	-0.9	-0.8	-1.4	-1.0	-1.1	-1.1
Pavlov. Cond. index score	1.5	1.9	4.6	0.9	-1.1	-0.7	-1.2	-1.3	-1.3	-2.1	-1.4	-1.6	-1.5
Pavlov. Cond. latency score	2.1	2.6	5.2	1.1	-1.4	-1.0	-1.5	-1.6	-1.6	-2.3	-1.7	-1.9	-1.7
Pavlov. Cond. lever contacts	2.1	2.6	3.9	1.3	-1.6	-1.2	-1.6	-1.8	-1.6	-2.0	-1.7	-1.7	-1.5
Pavlov. Cond. magazine entry number	1.1	1.4	4.0	-0.6	0.9	0.4	1.0	1.0	1.1	2.0	1.2	1.4	1.3
Pavlov. Cond. intertrial magazine entries	0.2	0.3	1.2	1.1	-0.5	-0.3	-0.1	0.0	0.1	0.6	0.1	0.5	0.8
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.9	5.4	0.7	-1.0	-0.5	-1.1	-1.3	-1.3	-2.3	-1.4	-1.7	-1.6
Pavlov. Cond. response bias	1.0	1.2	3.4	0.6	-0.8	-0.5	-0.9	-1.1	-1.0	-1.8	-1.2	-1.3	-1.3
Pavlov. Cond. lever latency	0.3	0.3	0.9	-0.8	0.6	0.9	0.6	0.4	0.3	-0.9	0.1	0.0	0.0
Pavlov. Cond. magazine entry latency	1.2	1.5	2.3	0.7	-1.3	-1.5	-1.5	-1.2	-1.4	-0.4	-1.1	-1.3	-1.3
Pavlov. Cond. change in total contacts	1.1	1.8	2.6	1.5	-1.6	-1.6	-1.6	-1.5	-1.4	-0.3	-1.2	-1.1	-0.9
Pavlov. Cond. index score	1.2	1.6	3.1	1.1	-1.5	-1.8	-1.6	-1.4	-1.3	0.1	-1.0	-1.1	-1.1
Pavlov. Cond. latency score	1.6	2.2	3.8	1.1	-1.6	-1.9	-1.8	-1.6	-1.6	-0.2	-1.3	-1.5	-1.4
Pavlov. Cond. lever contacts	0.3	0.4	1.0	0.8	-0.6	-1.0	-0.6	-0.5	-0.3	1.0	-0.1	-0.0	-0.1
Pavlov. Cond. magazine entry number	1.2	1.5	3.0	-0.3	1.0	1.4	1.4	1.3	1.5	0.5	1.0	1.5	1.7
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.5	-0.5	0.5	0.5	0.7	0.3	0.2	-0.1	0.4	0.3	0.1
Pavlov. Cond. lever-magazine prob. diff.	1.4	1.9	3.3	1.0	-1.5	-1.8	-1.6	-1.5	-1.5	-0.2	-1.1	-1.3	-1.4
Pavlov. Cond. response bias	0.4	0.5	1.5	0.9	-0.8	-1.2	-0.7	-0.6	-0.6	1.0	-0.1	-0.1	-0.1
Time in closed arm before self-admin	1.4	1.8	6.2	-0.0	-0.8	-0.5	-1.0	-1.2	-0.3	-2.5	-1.5	-1.8	-1.8
Time in closed arm after self-admin	0.1	0.2	0.4	-0.3	-0.2	-0.3	-0.1	-0.2	-0.5	-0.7	-0.5	-0.5	-0.4
Time in open arm before self-admin	0.4	0.5	1.7	0.1	-0.1	-0.1	0.2	0.7	-0.3	1.3	0.4	0.8	1.2
Time in open arm after self-admin	0.5	0.5	1.6	1.0	-0.2	-0.2	0.0	0.2	0.4	1.3	0.7	0.9	1.0
Bone: periosteal estimation	0.8	1.7	4.9	-0.3	1.0	0.5	1.0	1.3	1.4	2.2	1.6	1.5	1.1
Bone: periosteal perimeter	1.0	1.8	3.0	-0.9	1.5	1.0	1.4	1.2	1.5	1.6	1.7	1.4	0.8
Bone: post-yield work	3.8	5.6	8.8	-2.1	3.0	2.7	2.5	2.9	2.7	1.5	2.5	2.0	1.3
Progressive ratio test 1 active lever presses	0.2	0.3	0.7	0.7	0.0	0.3	0.0	0.5	0.5	0.6	0.5	0.6	0.8
Progressive ratio test 1 breakpoint	0.3	0.3	0.8	0.6	0.2	0.4	0.1	0.6	0.6	0.7	0.6	0.7	0.9
Progressive ratio test 1 inactive lever presses	0.8	1.2	3.5	0.6	0.5	0.3	0.5	1.0	0.9	1.9	1.7	1.3	1.2
Progressive ratio test 2 active lever presses	0.2	0.3	0.6	0.8	-0.8	-0.6	-0.8	-0.3	-0.4	0.2	-0.6	-0.3	0.0
Progressive ratio test 2 breakpoint	0.3	0.4	0.9	0.8	-0.9	-0.8	-0.9	-0.4	-0.6	0.1	-0.7	-0.4	-0.1
Progressive ratio test 2 inactive lever presses	0.2	0.3	1.5	1.2	-0.7	-0.5	-0.8	0.1	-0.1	0.5	-0.2	0.0	0.4
Incentive Sensitization - Responses	1.6	2.2	3.5	1.2	-1.7	-1.9	-1.8	-1.3	-1.6	-0.6	-1.6	-1.5	-1.3
Incentive Sensitization - Breakpoint	2.0	2.6	3.8	1.2	-1.8	-1.9	-2.0	-1.5	-1.7	-0.8	-1.7	-1.7	-1.5
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.3	0.5	-0.0	0.1	-0.0	0.2	0.2	0.5	0.3	0.4	0.5
Progressive ratio	0.4	0.6	1.6	-0.4	0.6	0.8	1.0	0.7	0.9	0.1	0.6	0.9	1.3
Food seeking constrained by brief footshock	0.1	0.1	0.3	0.3	0.3	0.4	0.4	-0.0	0.3	-0.6	0.4	0.1	-0.1
Seeking ratio, punishment vs. effort	0.2	0.3	1.6	-0.4	0.5	0.2	0.0	-0.2	-0.1	-0.4	0.2	-0.5	-1.3
Retroperitoneal fat weight	1.6	6.9	28.8	-5.4	3.4	2.7	2.9	2.2	1.9	0.4	1.8	1.0	0.1
Reaction time number correct	2.3	4.4	9.8	3.1	-2.5	-2.5	-2.5	-2.2	-2.0	-0.2	-1.8	-1.4	-1.0
Reaction time mean minus median	0.3	0.8	1.4	-0.0	-0.9	-0.9	-0.7	-1.0	-1.2	-1.1	-1.0	-1.0	-0.8
Reaction time mean minus median AUC	0.2	0.5	1.2	0.2	-0.6	-0.5	-0.4	-0.7	-0.8	-1.1	-0.6	-0.7	-0.7
Reaction time num false alarms	0.4	0.6	1.4	-0.0	-0.8	-1.2	-0.8	-0.9	-0.8	0.1	-0.6	-0.8	-0.9
Reaction time num false alarms AUC	0.6	0.9	2.4	0.3	-0.9	-1.5	-1.0	-1.1	-0.9	0.3	-0.6	-0.9	-1.1
Reaction time trials correct on left	2.3	4.4	9.8	3.1	-2.5	-2.5	-2.5	-2.2	-2.0	-0.2	-1.8	-1.4	-1.0
Reaction time trials on left	2.4	4.5	9.8	3.1	-2.6	-2.5	-2.5	-2.2	-2.1	-0.3	-1.8	-1.4	-1.1
Reaction time mean	0.1	0.2	0.7	-0.8	-0.0	0.2	0.1	-0.1	-0.3	-0.7	-0.3	-0.3	-0.1
Reaction time mean AUC	0.1	0.2	0.9	-0.9	0.1	0.2	0.2	0.0	-0.3	-0.7	-0.2	-0.2	-0.2
Median of all reaction times	0.1	0.2	1.2	-1.1	0.3	0.5	0.3	0.2	0.1	-0.5	-0.0	0.0	0.1
Reaction time omissions	0.8	1.1	1.8	-0.3	-0.8	-1.0	-0.9	-1.0	-1.4	-1.0	-1.1	-1.3	-1.3
Reaction time false alarm rate	0.2	0.3	1.8	-1.3	0.6	0.1	0.5	0.3	0.4	0.4	0.5	0.1	-0.3
Reaction time premature initiation rate	0.1	0.2	0.9	0.5	-0.5	-0.1	-0.2	-0.1	-0.0	-0.1	-0.6	0.3	1.0
Reaction time premature initiations	0.8	1.5	3.4	1.9	-1.7	-1.2	-1.4	-1.2	-1.0	-0.3	-1.5	-0.5	0.3
Std. dev. reaction times	0.0	0.1	0.3	-0.1	-0.3	-0.1	0.0	-0.2	-0.3	-0.6	-0.2	-0.1	-0.0
Reaction time trials completed	2.4	4.5	9.8	3.1	-2.6	-2.5	-2.5	-2.2	-2.1	-0.3	-1.8	-1.4	-1.1
Reaction time trials AUC	2.7	5.2	10.9	3.3	-2.8	-2.7	-2.7	-2.4	-2.2	-0.5	-2.1	-1.6	-1.2
Run reversals in cocaine runway, females	0.8	0.8	1.9	1.4	-1.2	-1.0	-1.0	-0.7	-0.8	0.1	-0.9	-0.3	0.3
Run reversals in cocaine runway, males	0.3	0.3	0.7	0.8	-0.2	-0.1	-0.0	0.1	0.2	0.8	0.4	0.6	0.8
Latency to leave start box in cocaine runway	0.1	0.1	0.3	-0.5	0.5	0.4	0.5	0.1	0.3	0.0	0.6	0.3	0.0
Latency to leave start box in cocaine runway, F	0.6	0.7	2.4	-1.5	1.2	1.0	0.8	0.3	0.6	-0.2	0.8	0.1	-0.3
Latency to leave start box in cocaine runway, M	0.3	0.3	1.4	1.2	-0.8	-0.5	-0.4	-0.3	-0.3	0.2	-0.3	0.2	0.5
Std. dev. time between licks in bursts	0.3	0.5	1.1	1.0	-1.0	-0.8	-0.7	-0.7	-0.6	-0.1	-0.6	-0.2	0.2
Total sessions with >9 infusions	0.1	0.2	0.4	0.1	0.3	0.6	0.3	0.7	0.3	0.0	0.0	0.4	0.6
Short access day 1 total inactive lever presses	0.3	0.4	0.9	0.9	-0.7	-0.7	-0.6	-0.6	-0.4	0.8	-0.1	0.1	0.5
Short access day 10 total inactive lever presses	0.5	1.1	2.8	0.6	-0.8	-1.1	-1.0	-1.4	-0.8	-0.7	-0.6	-1.3	-1.7
Short access day 1 total infusions	0.0	0.1	0.3	0.6	-0.0	0.1	-0.0	0.0	0.1	0.2	-0.1	0.2	0.3
Short access day 10 total infusions	0.3	0.4	1.7	1.3	-0.3	-0.1	-0.1	0.3	0.1	0.7	0.3	0.6	0.9
Short access total infusions	0.2	0.2	0.8	0.5	0.1	0.2	0.1	0.5	0.4	0.7	0.2	0.6	0.9
Short access day 1 locomotion	0.8	1.0	1.7	-0.6	0.9	1.0	1.0	1.3	1.0	0.8	0.9	1.1	1.1
Short access day 10 total locomotion	0.2	0.4	1.8	-0.3	0.1	0.4	0.4	0.8	0.2	0.4	0.2	0.8	1.3
Short access total locomotion	0.4	0.4	2.3	0.3	-0.2	0.1	0.1	0.7	0.1	0.8	0.1	0.9	1.5
One hour access (0.3 mA shock)	0.9	1.0	1.8	0.2	-0.9	-0.7	-1.3	-0.7	-1.1	-1.2	-1.2	-1.3	-1.1
Compulsive drug intake	0.3	0.4	1.2	1.0	-0.4	-0.4	-0.1	0.1	0.2	1.1	0.6	0.6	0.8
One hour access (shock baseline)	0.9	1.4	2.4	0.7	-1.2	-0.8	-1.4	-0.9	-1.3	-1.5	-1.5	-1.4	-1.0
Social response proportion	4.3	4.8	9.2	-2.8	3.0	2.7	2.6	2.2	2.2	0.4	2.2	1.4	0.5
Social responses	0.5	0.6	1.3	-0.6	0.9	0.6	1.0	0.5	0.7	1.0	1.2	0.8	0.4
Social time	3.2	4.3	6.1	-1.2	2.0	2.0	2.2	1.8	2.5	2.0	2.3	2.4	2.2
Soleus weight	0.2	0.6	1.6	1.3	-1.1	-1.1	-0.7	-0.8	-0.8	0.4	-0.1	-0.2	-0.1
Bone: stiffness	0.5	0.8	1.8	-1.3	1.3	0.6	1.0	0.8	0.8	0.8	1.0	0.5	-0.3
Tibialis anterior weight	0.0	0.0	0.1	0.3	-0.1	0.0	-0.0	-0.3	0.1	-0.0	0.0	0.0	-0.1
Time to tail flick, vehicle, before self-admin	0.8	0.8	3.1	0.1	-0.4	-0.6	-0.7	-1.0	0.0	-1.1	-0.6	-1.3	-1.8
Time to tail flick, vehicle, after self-admin	0.8	1.0	2.2	0.9	-1.2	-1.3	-1.1	-0.8	-1.5	-0.4	-1.0	-0.9	-0.7
Time to tail flick, test, before self-admin	0.3	0.3	0.7	0.5	-0.6	-0.5	-0.5	-0.7	-0.9	-0.3	-0.5	-0.3	-0.2
Time to tail flick, test, after self-admin	0.8	0.8	2.6	1.6	-1.2	-1.2	-0.8	-0.8	-0.9	0.4	-0.5	-0.2	0.1
Delta time to tail flick, vehicle, before/after SA	0.6	0.6	1.7	0.4	-0.9	-0.8	-0.8	-0.6	-1.3	-0.3	-1.1	-0.6	-0.1
Delta time to tail flick, test, before/after SA	0.5	0.5	1.1	1.0	-0.9	-0.9	-0.8	-0.7	-0.6	-0.1	-0.5	-0.5	-0.4
Tibia length	0.4	1.2	6.8	0.8	-0.3	-0.9	0.1	0.4	0.4	2.6	1.0	1.1	1.0
Ambulatory time before self-admin	0.7	1.0	2.8	-1.4	1.3	1.4	1.1	0.7	1.7	-0.1	0.6	0.6	0.2
Ambulatory time after self-admin	0.1	0.1	0.3	-0.1	-0.2	-0.2	-0.3	-0.5	-0.4	-0.2	-0.3	-0.4	-0.5
Bone: tissue strength	0.3	0.3	1.1	-0.8	0.1	-0.4	-0.3	-0.3	-0.3	0.1	-0.1	-0.6	-1.1
Total heroin consumption	1.1	1.3	3.3	0.1	0.6	0.8	0.9	1.3	1.0	1.3	1.0	1.5	1.8
Bone: trabecular number	0.7	1.2	2.0	1.1	-1.4	-1.2	-1.3	-1.1	-1.1	-0.5	-1.4	-0.9	-0.4
Bone: trabecular spacing	3.5	4.7	12.0	-3.5	3.0	2.4	2.7	2.1	1.6	0.2	2.1	1.0	-0.2
Bone: trabecular thickness	0.6	0.7	3.0	1.7	-1.0	-0.8	-0.8	-0.2	-0.2	0.8	-0.2	0.3	0.8
Bone: trabecular tissue density	2.0	2.9	4.6	1.8	-2.0	-1.5	-2.1	-1.7	-1.6	-1.3	-2.0	-1.6	-1.2
Water consumed over 24 hours	2.1	2.8	5.8	1.8	-1.9	-2.4	-2.2	-1.2	-1.7	0.3	-1.4	-1.4	-1.2
Number of responses in last shaping day	1.3	1.5	2.4	0.2	-0.9	-0.8	-1.1	-1.5	-1.2	-1.6	-1.6	-1.4	-1.2