Hub : Genes

Ggnbp1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Ggnbp1 0.18 0.07 1.0e-11 0.1 0.1 0.09 0.1 4.5e-08 1.4e-08 1.8e-07 3.4e-08
2 Liver gene expression Ggnbp1 0.05 0.03 3.5e-04 0.03 0.03 0.03 0.03 2.7e-04 1.9e-04 1.4e-04 1.7e-04
3 PL gene expression Ggnbp1 0.15 0.06 0.0e+00 0.2 0.19 0.2 0.09 3.3e-21 1.2e-20 4.1e-21 1.0e-09
4 BLA gene expression Ggnbp1 0.18 0.08 8.7e-08 0.15 0.06 0.15 0.15 2.0e-08 3.1e-04 2.8e-08 1.6e-08
5 Brain gene expression Ggnbp1 0.2 0.08 1.1e-16 0.18 0.16 0.17 0.18 3.5e-16 4.8e-15 1.2e-15 2.7e-16
6 IC gene expression Ggnbp1 0.11 0.06 3.2e-03 0.03 0.06 0.01 0.04 2.4e-02 2.3e-03 8.7e-02 6.6e-03
7 NAcc gene expression Ggnbp1 0.19 0.06 0.0e+00 0.22 0.21 0.22 0.22 7.7e-33 2.4e-31 2.7e-32 1.6e-32
8 LHb gene expression Ggnbp1 0.32 0.14 6.0e-05 0.16 0.09 0.12 0.13 1.4e-04 3.8e-03 7.7e-04 5.8e-04
9 Brain intron excision ratio chr20_5104852_5110512 0.07 0.04 9.7e-03 -0 -0 -0 0.01 7.7e-01 7.7e-01 1.0e+00 2.5e-02
10 Adipose gene expression Ggnbp1 0.09 0.04 3.9e-06 0.04 0.04 0.03 0.04 2.4e-05 6.9e-05 1.6e-04 1.0e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density1.12.06.4-0.8-2.5-1.2-1.3-1.1-0.7-1.7-1.01.1-1.7
Area under the delay curve0.10.20.60.20.80.00.50.4-0.20.6-0.00.10.2
BMI with tail1.65.48.12.81.32.32.22.52.82.32.3-2.71.5
BMI without tail2.37.110.22.82.92.82.72.92.73.22.8-1.91.6
Body weight2.912.519.13.04.13.23.23.63.24.43.2-3.93.3
Weight adjusted by age1.82.79.71.22.70.81.31.00.61.11.2-1.53.1
Bone surface0.20.40.9-0.9-0.9-0.7-0.8-0.4-0.3-0.9-0.4-0.0-0.6
Bone volume0.20.41.8-0.5-1.3-0.5-0.6-0.2-0.2-0.8-0.30.2-0.9
Breakpoint value in progressive ratio session0.20.30.5-0.7-0.6-0.4-0.6-0.6-0.3-0.7-0.20.5-0.7
Number of licking bursts0.60.92.5-1.6-0.3-1.2-1.3-0.8-0.9-0.7-0.80.6-0.7
Context. condit. distance diff. score7.38.811.6-3.3-3.2-3.3-3.4-3.2-2.8-3.0-3.21.9-1.8
Locomotion velocity, session 11.92.13.4-1.5-1.3-1.3-1.2-1.7-1.8-1.8-0.91.4-1.1
Locomotion distance, session 10.91.22.5-0.7-1.6-0.9-1.0-1.0-0.8-1.2-0.51.0-1.5
Locomotion velocity, session 20.80.91.5-1.2-1.1-1.0-1.1-0.7-0.8-1.0-0.80.6-1.2
Locomotion distance, session 20.71.01.7-0.7-1.2-1.1-1.1-1.2-0.9-1.3-1.00.5-0.4
Locomotion velocity, session 30.20.20.90.20.20.30.20.70.31.00.4-0.1-0.4
Locomotion distance, session 31.41.52.1-1.1-1.5-1.3-1.4-1.2-1.1-1.0-1.11.1-1.4
Stereotopy head waving bouts, day 30.60.72.4-0.01.60.50.50.70.30.90.8-1.01.1
Stereotopy head waving duration, day 30.60.72.90.31.70.60.70.70.20.90.6-0.61.1
Locomotion velocity, session 73.23.56.3-1.3-2.5-2.0-1.9-2.3-1.8-2.1-2.11.0-0.7
Locomotion distance, session 74.35.57.9-1.8-2.8-2.5-2.5-2.7-2.4-2.5-2.32.0-1.5
Stereotopy head waving bouts, day 70.30.41.40.00.90.50.50.4-0.10.30.81.2-0.3
Stereotopy head waving duration, day 70.60.82.20.51.50.90.90.90.50.91.20.20.3
Locomotion velocity, session 82.22.76.3-2.5-1.2-1.9-1.9-1.8-2.0-1.3-1.50.5-0.7
Locomotion distance, session 85.57.910.7-3.0-3.2-3.2-3.3-3.2-2.6-3.0-3.11.4-1.5
Degree of sensitization distance0.30.30.5-0.7-0.6-0.5-0.5-0.7-0.5-0.7-0.4-0.0-0.0
Degree of sensitization stereotypy0.50.53.3-0.4-0.1-0.1-0.1-0.2-0.4-0.50.11.8-1.2
Conditioned locomotion0.30.42.10.10.00.20.10.70.80.30.1-1.50.4
Cocaine response after cond. corrected0.20.30.9-0.1-0.6-0.2-0.3-0.30.3-0.4-0.7-0.90.5
Cocaine response after cond. not corrected0.20.20.9-0.10.40.30.20.30.50.30.0-1.00.7
Cocaine response before conditioning1.72.15.90.42.41.41.41.60.81.81.9-0.50.7
Saline control response4.25.68.72.92.52.82.92.62.42.32.2-1.01.3
Bone: connectivity density0.91.44.2-0.9-2.0-1.2-1.3-1.1-0.6-1.5-0.90.3-1.0
Bone: cortical apparent density1.72.33.61.90.51.81.81.91.91.11.5-1.20.7
Bone: cortical area0.10.10.30.10.10.10.10.50.30.40.2-0.3-0.1
Bone: cortical porosity0.70.74.0-0.50.7-0.3-0.2-0.4-1.20.0-0.42.0-0.8
Bone: cortical porosity0.70.83.4-0.80.7-0.6-0.4-0.7-1.4-0.2-0.41.8-0.5
Bone: cortical thickness0.81.32.41.5-0.11.31.21.61.41.11.0-0.4-0.6
Bone: cortical thickness2.42.95.32.10.32.01.92.22.31.51.7-1.30.1
Bone: cortical tissue density1.62.23.31.80.61.81.71.81.81.11.5-1.20.8
Condit. Reinf. active minus inactive responses0.40.41.4-0.4-0.4-0.4-0.3-0.7-0.9-0.7-0.31.2-0.5
Condit. Reinf. active-inactive response ratio0.60.61.10.90.81.01.00.80.70.80.9-0.10.2
Condit. Reinf. active responses0.20.30.7-0.2-0.7-0.4-0.3-0.8-0.6-0.6-0.10.8-0.4
Condit. Reinf. inactive responses0.70.92.5-0.5-1.6-0.8-0.8-1.1-0.7-1.0-0.60.9-1.0
Incentive salience index mean2.12.63.2-1.7-1.7-1.8-1.7-1.8-1.7-1.8-1.61.3-1.0
Condit. Reinf. lever presses4.46.18.7-2.7-2.8-2.9-3.0-2.6-2.3-2.6-2.71.1-1.2
Condit. Reinf. active minus inactive responses0.30.41.60.31.00.50.60.60.11.30.7-0.30.3
Condit. Reinf. active-inactive response ratio0.30.41.30.11.10.40.50.3-0.21.10.6-0.30.7
Condit. Reinf. active responses0.10.10.50.10.50.30.30.3-0.00.70.50.0-0.1
Condit. Reinf. inactive responses0.20.20.40.50.20.60.50.60.60.30.5-0.3-0.4
Condit. Reinf. lever presses0.60.82.1-0.6-0.6-0.9-0.8-0.8-1.1-0.6-0.81.4-1.1
Condit. Reinf. lever reinforcers received0.10.10.3-0.10.40.20.20.1-0.20.50.50.3-0.3
Conditioned reinforcement - actives0.00.10.30.1-0.5-0.10.30.0-0.2-0.3-0.20.30.2
Conditioned reinforcement - inactives0.10.10.30.50.40.30.4-0.1-0.2-0.10.10.40.4
Conditioned locomotion0.20.30.6-0.2-0.4-0.6-0.2-0.5-0.8-0.4-0.70.40.8
Patch foraging indifference point 0 sec2.75.08.32.62.22.82.92.32.12.12.2-1.31.4
Patch foraging indifference point AUC0.10.10.3-0.20.10.40.20.50.20.40.50.1-0.2
Delay disc. indifference point, 0s delay0.10.20.4-0.40.1-0.5-0.3-0.4-0.6-0.4-0.2-0.20.4
Delay disc. indifference point, 16s delay0.20.20.40.60.40.20.50.60.10.6-0.10.4-0.1
Delay disc. indifference point, 2s delay0.20.20.7-0.20.9-0.10.3-0.1-0.70.3-0.00.00.8
Delay disc. indifference point, 24s delay0.70.82.90.91.70.61.10.7-0.00.70.70.40.9
Delay disc. indifference point, 4s delay0.70.71.40.41.20.81.21.10.50.90.8-0.50.4
Delay disc. indifference point, 8s delay0.10.10.20.10.5-0.30.20.1-0.40.3-0.10.20.3
Indifference point function ln k0.50.91.8-1.1-0.5-0.9-1.0-0.7-0.9-1.0-1.30.6-0.9
Indifference point function log k0.50.91.8-1.1-0.5-0.9-1.0-0.7-0.9-1.0-1.30.6-0.9
Patch foraging total patch changes 0 sec2.75.28.42.72.22.82.92.32.22.12.2-1.31.4
Patch foraging total patch changes 12 sec2.02.64.21.81.22.02.01.71.81.51.8-1.00.9
Patch foraging total patch changes 18 sec2.53.86.22.51.32.32.22.12.41.51.9-1.41.3
Patch foraging total patch changes 24 sec0.40.72.31.5-0.10.91.00.70.90.50.90.10.1
Patch foraging total patch changes 6 sec2.23.46.22.51.32.32.41.91.81.71.9-0.80.9
Patch foraging time to switch 0 sec0.51.12.41.50.70.50.60.81.30.90.7-1.61.3
Patch foraging water rate 0 sec0.30.51.10.70.71.11.10.50.40.70.4-0.70.8
Patch foraging water rate 12 sec0.10.31.10.3-0.80.40.30.40.3-0.2-0.20.3-1.1
Patch foraging water rate 18 sec0.30.50.90.80.50.90.90.80.71.00.7-0.60.3
Patch foraging water rate 24 sec0.20.30.90.50.21.00.80.60.60.50.5-0.2-0.4
Patch foraging water rate 6 sec0.20.30.70.60.30.70.50.80.70.80.2-0.6-0.1
Seeking ratio, delayed vs. immediate footshock1.72.14.10.71.41.71.32.01.71.71.8-0.9-0.7
Distance traveled before self-admin0.20.21.6-0.1-0.0-0.0-0.30.20.6-0.10.1-1.30.4
Distance traveled after self-admin1.01.32.30.61.01.21.01.51.51.11.1-1.30.3
Extensor digitorum longus weight0.10.61.3-1.0-0.0-1.1-1.0-0.6-0.9-0.0-1.1-0.0-0.1
Bone: elastic displacement0.20.20.70.60.40.30.60.0-0.30.3-0.10.80.1
Bone: elastic work0.10.20.50.70.40.50.70.30.20.20.2-0.00.4
Bone: endosteal estimation0.61.34.7-0.52.20.20.20.50.10.90.5-1.52.1
Bone: endosteal perimeter0.30.72.3-1.50.4-1.1-1.1-0.7-0.7-0.1-0.6-0.70.7
Epididymis fat weight4.615.631.45.61.74.54.34.25.03.54.0-3.31.3
Delta time in closed arm before/after self-admin0.30.31.10.70.30.20.30.20.40.30.4-1.01.0
Delta time in open arm before/after self-admin0.10.10.3-0.1-0.00.00.30.2-0.1-0.3-0.20.5-0.2
Diff in mean of infusions in LGA sessions1.41.73.3-1.2-1.8-1.3-1.6-1.5-0.9-1.3-1.50.5-0.8
Delay discount exponential model param0.20.20.7-0.2-0.8-0.1-0.5-0.50.2-0.60.0-0.2-0.1
Extinction: sum of active levers before priming0.50.51.1-0.8-0.6-0.8-0.9-0.9-0.7-1.1-0.60.10.2
Active lever presses in extinction session 60.10.10.30.5-0.2-0.10.1-0.5-0.5-0.30.10.60.4
Bone: final force2.94.75.92.41.82.42.42.22.42.01.9-2.31.7
Bone: final moment2.13.44.22.11.72.02.01.81.91.81.6-1.91.7
Food consumed during 24 hour testing period0.50.71.80.51.00.30.30.40.90.60.5-1.31.3
Glucose2.53.97.9-2.60.8-2.3-2.1-2.5-2.8-1.0-2.11.11.0
Heart weight1.01.65.91.02.40.91.21.00.21.80.9-0.61.3
Delay discount hyperbolic model param0.20.20.7-0.1-0.8-0.1-0.5-0.50.3-0.6-0.0-0.2-0.1
Intermittent access intake day 1-15 change0.10.20.40.10.10.70.30.50.50.40.6-0.0-0.5
Intermittent access intake escalation0.30.71.40.70.31.21.01.00.90.91.20.1-0.5
Intermittent access intake escalation 20.10.10.3-0.5-0.1-0.2-0.2-0.1-0.3-0.2-0.20.4-0.3
Intermitt. access day 1 inactive lever presses0.10.30.7-0.80.1-0.3-0.8-0.6-0.1-0.7-0.2-0.6-0.2
Intermitt. access day 15 inactive lever presses0.20.51.20.51.10.90.60.40.50.40.7-0.51.0
Intermitt. access escalation Index1.52.15.7-1.6-2.4-1.2-1.7-1.1-0.6-1.3-1.00.5-2.0
Intermittent access day 1 total infusions1.52.44.3-0.7-1.5-1.6-0.9-1.8-2.1-1.8-1.82.0-0.1
Intermittent access day 15 total infusions0.20.31.40.2-0.7-0.00.3-0.2-0.5-0.4-0.11.2-0.5
Intermittent access terminal intake (last 3 days)0.20.21.50.3-0.40.00.4-0.2-0.6-0.3-0.11.2-0.3
Intermittent access total infusions0.40.51.90.0-0.6-0.40.1-0.6-1.0-0.7-0.51.4-0.3
Intermittent access day 1 locomotion0.10.10.30.1-0.6-0.20.1-0.4-0.5-0.4-0.50.30.4
Intermittent access day 15 total locomotion0.50.91.71.00.71.01.11.00.71.10.7-0.81.3
Intermittent access total locomotion0.20.20.70.6-0.00.30.80.50.10.40.2-0.00.7
Intermittent access standard deviation1.73.55.72.11.92.42.21.91.91.62.1-1.31.0
Left kidney weight2.210.115.53.03.23.13.03.83.33.93.0-3.12.0
Right kidney weight2.310.315.62.83.43.02.93.63.33.92.9-3.52.6
Cocaine induced anxiety0.10.20.5-0.7-0.6-0.2-0.7-0.20.2-0.3-0.1-0.5-0.5
Post-drug Anxiety0.20.20.6-0.1-0.10.40.00.50.70.40.8-0.7-0.5
Baseline Anxiety0.20.30.60.80.40.50.70.60.30.30.7-0.40.2
Tail length0.93.615.10.33.91.51.51.70.62.61.6-1.01.8
Length with tail1.46.118.40.94.31.71.92.11.13.31.8-2.43.1
Length without tail1.96.114.81.62.81.71.82.11.92.51.5-3.93.6
Times rat made contact with spout0.30.31.50.6-0.30.30.40.20.1-0.1-0.01.2-0.8
Lifetime Intake0.30.31.40.2-0.3-0.30.2-0.5-0.9-0.6-0.41.20.1
Liver weight, left0.71.13.8-0.51.90.1-0.10.50.51.10.3-1.71.5
Liver weight, right0.20.41.3-1.10.5-0.5-0.6-0.1-0.5-0.0-0.1-0.90.8
Locomotor activity0.71.02.30.21.31.10.91.41.11.50.9-0.3-0.5
Locomotor testing distance0.30.61.30.20.80.80.61.01.01.10.5-0.6-0.1
Locomotor testing rearing0.51.01.60.51.00.91.00.91.21.11.0-1.30.8
Locomotion in novel chamber0.10.10.40.0-0.30.2-0.00.30.20.0-0.6-0.2-0.4
Locomotion in novel chamber post-restriction1.01.62.21.40.81.31.41.41.31.31.0-1.50.9
Fecal boli incidents, locomotor time 10.40.51.1-0.4-0.3-1.0-0.4-1.0-0.7-1.1-0.70.40.7
Change in fecal boli incidents, locomotor task0.60.61.40.30.80.80.70.70.70.61.1-1.20.5
Time >=10cm from walls, locomotor time 11.61.65.70.61.11.00.81.21.60.81.0-2.41.4
Bouts of movement, locomotor time 10.60.73.2-0.9-0.8-0.5-0.7-0.3-0.2-0.7-0.50.6-1.8
Total resting periods, locomotor time 10.50.62.1-1.0-0.7-0.5-0.7-0.4-0.4-0.9-0.50.5-1.4
Rest time, locomotor task time 10.50.61.2-1.1-0.3-1.0-0.9-0.6-0.9-0.9-0.60.6-0.2
Distance moved, locomotor task time 11.01.41.91.40.91.41.41.11.21.31.3-0.90.9
Vertical activity count, locomotor time 11.53.64.92.11.52.22.11.82.01.92.0-1.71.4
Time >=10cm from walls, locomotor time 21.72.58.21.12.51.11.31.00.90.81.4-1.52.9
Bouts of movement, locomotor time 20.20.32.0-0.5-0.20.40.20.40.10.20.20.4-1.4
Total resting periods, locomotor time 20.30.53.0-1.0-0.5-0.1-0.3-0.0-0.4-0.2-0.20.8-1.7
Rest time, locomotor task time 21.11.32.9-1.7-1.1-1.3-1.6-1.0-0.7-1.2-1.1-0.3-0.9
Distance moved, locomotor task time 22.12.65.62.21.61.41.81.11.11.41.5-0.82.4
Vertical activity count, locomotor time 21.72.45.71.91.51.31.71.21.01.41.5-1.02.4
Light reinforcement 10.92.25.01.31.21.61.21.42.11.30.8-2.21.2
Light reinforcement 20.60.92.20.71.10.80.70.51.00.60.4-1.51.5
Bone: marrow area0.71.55.1-0.42.30.30.40.60.31.00.7-1.62.2
Bone: maximum diameter0.71.33.3-1.8-0.3-1.6-1.6-1.1-1.3-0.7-1.20.2-0.1
Bone: maximum force1.11.92.51.41.21.41.51.41.41.11.2-1.61.4
Bone: maximum moment0.61.11.91.11.11.01.11.00.90.90.9-1.11.4
Mean time between licks in bursts1.43.57.3-2.7-1.1-2.3-2.4-1.7-2.0-1.8-1.70.8-1.2
Mean num. licks in bursts0.61.03.21.80.21.31.51.00.90.70.70.10.2
Cd content in liver0.50.63.01.00.50.30.5-0.50.20.00.3-1.11.7
Co content in liver2.52.94.02.01.71.61.71.41.61.71.9-1.71.5
Cu content in liver0.30.31.80.5-0.70.20.10.20.3-0.10.30.7-1.3
Fe content in liver0.60.71.21.10.60.90.90.90.90.70.7-0.70.8
K content in liver1.51.42.3-1.1-1.4-1.5-1.5-0.9-1.0-1.0-1.10.9-1.3
Mg content in liver2.93.04.6-2.1-2.0-1.9-2.1-1.4-1.3-1.5-1.40.8-2.0
Mn content in liver1.92.24.4-2.1-1.1-1.9-1.9-1.5-1.5-1.1-1.8-0.1-0.0
Na content in liver0.20.31.60.1-0.30.20.00.60.40.30.00.5-1.3
Rb content in liver0.30.30.8-0.4-0.7-0.7-0.6-0.8-0.4-0.9-0.4-0.00.0
Se content in liver1.61.84.4-2.1-0.5-1.4-1.5-1.4-1.7-0.8-1.11.3-1.1
Sr content in liver0.30.31.40.10.6-0.3-0.1-0.4-0.50.2-0.3-0.31.2
Zn content in liver0.20.20.4-0.40.2-0.5-0.4-0.5-0.6-0.2-0.1-0.40.6
Bone: minimum diameter0.20.30.8-0.90.6-0.7-0.6-0.3-0.40.2-0.1-0.80.7
Time in familiar zone, hab. session 10.70.72.9-0.0-1.0-0.6-0.5-0.5-0.6-0.7-0.81.7-1.0
Time in novel zone, hab. session 11.01.02.50.31.20.90.80.70.71.01.1-1.61.1
Total zone transitions, hab. session 10.50.71.6-0.8-1.1-0.6-0.8-0.6-0.4-0.9-0.40.8-1.3
Total locomotion distance, hab. session 10.81.12.9-0.9-1.7-1.1-1.3-0.7-0.6-1.0-0.70.6-1.3
Locomotion velocity, hab. session 10.50.71.8-0.8-1.3-0.9-1.1-0.5-0.5-0.7-0.50.6-1.2
Time in familiar zone, hab. session 20.60.61.50.4-0.10.70.51.21.20.70.7-0.3-1.2
Time in novel zone, hab. session 20.40.42.30.31.00.20.4-0.4-0.60.00.00.01.5
Total zone transitions, hab. session 20.30.31.3-0.3-1.1-0.3-0.50.20.5-0.10.1-0.4-1.1
Total locomotion distance, hab. session 21.21.55.0-0.9-2.2-1.1-1.4-0.6-0.1-1.1-1.30.1-1.7
Locomotion velocity, hab. session 21.72.36.3-1.3-2.5-1.5-1.8-1.0-0.5-1.4-1.60.4-1.9
Novel to familiar place preference ratio0.30.30.8-0.10.1-0.2-0.1-0.6-0.6-0.8-0.80.90.2
Novelty place preference0.20.20.8-0.10.2-0.1-0.0-0.5-0.6-0.6-0.70.90.1
Time in novel zone, NPP test0.20.20.8-0.10.3-0.00.1-0.4-0.5-0.5-0.60.90.1
Total zone transitions, NPP test1.72.54.3-1.4-2.1-1.6-1.7-1.7-1.2-1.8-1.21.2-1.6
Total locomotion distance, NPP test1.52.04.9-0.9-2.2-1.5-1.5-1.7-1.1-1.6-1.40.6-0.9
Locomotion velocity, NPP test2.02.96.6-1.1-2.6-1.9-1.9-1.9-1.2-1.9-1.70.8-1.2
Intraocular pressure0.10.10.20.20.2-0.1-0.10.00.10.50.40.20.4
Delta distance traveled before/after self-admin1.11.22.30.71.51.21.41.30.61.41.30.10.1
Delta ambulatory time before/after self-admin0.91.12.00.51.41.21.21.30.71.31.2-0.0-0.0
Parametrial fat weight1.74.06.92.21.02.01.92.22.61.81.8-2.61.2
Pavlov. Cond. lever latency7.89.812.53.42.83.33.23.43.53.33.3-2.91.9
Pavlov. Cond. magazine entry latency3.34.26.0-2.4-1.7-2.0-2.0-1.8-2.3-1.9-1.92.4-2.0
Pavlov. Cond. change in total contacts1.21.32.4-1.4-0.8-1.0-0.9-1.1-1.4-1.1-0.81.5-1.2
Pavlov. Cond. index score6.17.79.7-3.1-2.5-2.9-2.8-2.7-3.1-2.7-2.92.7-2.0
Pavlov. Cond. latency score6.48.110.2-3.2-2.6-2.9-2.9-2.8-3.2-2.8-3.02.7-2.1
Pavlov. Cond. lever contacts6.17.39.4-2.9-2.5-2.9-2.8-3.0-3.1-2.9-2.82.2-1.4
Pavlov. Cond. magazine entry number2.63.34.52.11.51.81.81.62.01.71.9-2.01.7
Pavlov. Cond. intertrial magazine entries1.01.22.81.70.81.11.20.51.00.61.5-0.71.3
Pavlov. Cond. lever-magazine prob. diff.6.27.69.7-3.0-2.5-2.9-2.8-2.7-3.1-2.8-2.82.7-1.9
Pavlov. Cond. response bias4.35.37.2-2.7-1.9-2.4-2.4-2.2-2.6-2.3-2.42.3-1.6
Pavlov. Cond. lever latency0.20.21.1-0.20.10.20.10.00.4-0.00.4-1.10.7
Pavlov. Cond. magazine entry latency0.60.71.3-0.8-0.2-1.0-0.8-0.9-1.1-0.8-1.00.8-0.1
Pavlov. Cond. change in total contacts0.10.21.00.10.0-0.1-0.00.0-0.40.0-0.01.0-0.7
Pavlov. Cond. index score0.30.41.1-0.4-0.2-0.7-0.5-0.5-0.9-0.3-0.81.0-0.6
Pavlov. Cond. latency score0.20.20.7-0.3-0.1-0.5-0.4-0.3-0.7-0.1-0.70.8-0.5
Pavlov. Cond. lever contacts0.10.10.80.30.0-0.1-0.00.1-0.30.1-0.30.9-0.6
Pavlov. Cond. magazine entry number0.10.10.40.20.10.50.40.40.50.20.6-0.30.0
Pavlov. Cond. intertrial magazine entries0.50.72.1-1.5-0.8-0.7-0.9-0.6-0.4-0.7-0.20.6-1.3
Pavlov. Cond. lever-magazine prob. diff.0.20.30.9-0.3-0.2-0.6-0.5-0.4-0.8-0.3-0.70.9-0.5
Pavlov. Cond. response bias0.40.51.5-0.4-0.4-0.8-0.7-0.6-0.9-0.4-0.91.2-0.7
Time in closed arm before self-admin0.10.10.1-0.30.2-0.4-0.2-0.2-0.30.3-0.20.10.4
Time in closed arm after self-admin0.10.10.40.10.0-0.6-0.2-0.3-0.30.3-0.3-0.20.6
Time in open arm before self-admin0.60.72.0-0.7-0.4-0.6-0.6-0.8-1.0-1.0-0.61.4-0.7
Time in open arm after self-admin0.40.41.3-0.6-0.5-0.1-0.1-0.2-0.6-0.8-0.41.1-0.9
Bone: periosteal estimation0.40.82.2-0.11.50.40.30.90.41.00.6-1.31.2
Bone: periosteal perimeter0.10.20.5-0.60.7-0.3-0.30.0-0.20.5-0.2-0.40.3
Bone: post-yield work0.30.51.1-1.0-0.1-0.7-0.7-0.8-0.7-0.7-0.1-0.30.9
Progressive ratio test 1 active lever presses0.30.30.70.10.1-0.30.1-0.6-0.8-0.8-0.50.60.9
Progressive ratio test 1 breakpoint0.30.30.70.10.1-0.30.1-0.6-0.8-0.7-0.60.60.9
Progressive ratio test 1 inactive lever presses0.20.20.60.8-0.30.60.50.30.60.00.4-0.50.2
Progressive ratio test 2 active lever presses0.40.50.8-0.3-0.8-0.7-0.4-0.6-0.8-0.9-0.80.8-0.4
Progressive ratio test 2 breakpoint0.40.50.9-0.3-0.8-0.7-0.4-0.6-0.8-0.9-0.71.0-0.4
Progressive ratio test 2 inactive lever presses0.71.22.3-0.8-0.8-1.1-0.8-1.3-1.4-1.5-1.30.90.0
Incentive Sensitization - Responses0.50.81.8-0.9-0.9-0.8-0.9-0.6-0.7-0.6-0.90.9-1.3
Incentive Sensitization - Breakpoint0.50.71.9-0.9-0.9-0.8-0.9-0.6-0.6-0.6-0.80.8-1.4
Sum of active levers in priming session hrs 5-60.40.40.9-0.60.3-0.3-0.5-0.7-0.9-0.4-0.71.00.2
Progressive ratio5.38.412.02.72.53.22.93.53.23.23.3-2.71.1
Food seeking constrained by brief footshock0.10.20.70.50.5-0.10.30.1-0.2-0.10.00.40.8
Seeking ratio, punishment vs. effort3.55.07.3-2.0-1.5-2.5-2.1-2.7-2.6-2.6-2.52.4-0.6
Retroperitoneal fat weight0.10.41.20.8-0.20.50.40.40.70.80.5-1.10.5
Reaction time number correct1.12.13.31.71.11.81.71.51.61.21.8-1.10.6
Reaction time mean minus median1.23.15.4-2.3-1.1-2.0-1.8-2.0-2.0-1.4-1.71.5-1.2
Reaction time mean minus median AUC1.64.17.0-2.3-1.0-2.3-2.0-2.7-2.6-2.0-1.92.0-0.6
Reaction time num false alarms0.10.21.0-0.7-0.4-0.2-0.40.00.00.10.3-0.1-1.0
Reaction time num false alarms AUC0.20.31.4-0.7-0.1-0.0-0.30.40.20.40.5-0.1-1.2
Reaction time trials correct on left1.12.13.31.71.11.81.71.51.61.21.8-1.10.6
Reaction time trials on left1.12.03.21.61.11.81.61.41.51.21.8-1.00.6
Reaction time mean1.93.05.2-2.0-1.1-2.2-2.0-2.3-2.0-1.8-1.70.9-0.0
Reaction time mean AUC1.82.85.1-1.9-1.0-2.1-1.9-2.3-2.0-1.7-1.50.90.1
Median of all reaction times1.31.83.4-1.4-0.9-1.7-1.6-1.8-1.6-1.5-1.30.40.3
Reaction time omissions1.11.73.1-1.8-1.6-1.3-1.5-1.5-1.2-1.3-1.10.6-0.7
Reaction time false alarm rate0.71.02.7-1.6-0.7-1.1-1.2-0.6-0.9-0.4-0.60.6-1.4
Reaction time premature initiation rate0.10.20.90.50.20.20.20.20.30.0-0.3-0.50.9
Reaction time premature initiations0.81.42.41.50.91.31.31.21.30.80.8-1.21.3
Std. dev. reaction times1.73.15.9-2.4-0.7-2.1-1.9-2.1-2.2-1.5-1.51.6-0.8
Reaction time trials completed1.12.03.21.61.11.81.61.41.51.21.8-1.00.6
Reaction time trials AUC1.12.03.21.61.11.81.61.41.61.21.8-1.10.7
Run reversals in cocaine runway, females0.20.20.80.90.00.10.50.20.00.50.1-0.30.9
Run reversals in cocaine runway, males1.41.42.2-1.5-0.9-1.5-1.4-1.1-1.1-1.5-1.40.8-0.4
Latency to leave start box in cocaine runway0.91.12.2-0.9-0.7-1.5-1.3-1.3-0.9-1.1-1.30.10.0
Latency to leave start box in cocaine runway, F0.60.71.6-0.8-0.4-1.0-1.0-1.3-0.9-0.8-0.90.20.4
Latency to leave start box in cocaine runway, M0.30.30.7-0.3-0.5-0.8-0.7-0.2-0.1-0.5-0.8-0.4-0.2
Std. dev. time between licks in bursts1.92.66.4-2.5-1.1-2.2-2.2-1.2-1.7-1.0-1.40.3-1.1
Total sessions with >9 infusions0.20.31.10.30.50.20.6-0.2-0.6-0.30.11.00.5
Short access day 1 total inactive lever presses0.60.82.0-0.70.2-0.8-0.5-1.2-1.4-1.0-1.10.90.6
Short access day 10 total inactive lever presses0.20.42.2-0.5-0.70.0-0.6-0.10.7-0.30.1-0.5-1.5
Short access day 1 total infusions0.60.72.0-0.2-0.1-0.6-0.1-1.0-1.3-1.2-0.81.40.6
Short access day 10 total infusions0.20.21.00.2-0.40.20.4-0.5-0.5-0.60.11.0-0.3
Short access total infusions0.30.41.40.1-0.1-0.30.2-0.8-1.1-0.8-0.41.20.5
Short access day 1 locomotion0.60.71.4-0.8-1.0-0.9-0.9-1.0-0.7-1.2-0.70.7-0.6
Short access day 10 total locomotion0.61.12.50.31.61.10.71.31.00.70.8-1.41.1
Short access total locomotion0.10.21.00.00.60.20.20.00.0-0.20.1-0.51.0
One hour access (0.3 mA shock)1.92.23.7-1.4-1.9-1.6-1.6-1.0-1.0-1.3-1.71.2-1.9
Compulsive drug intake1.92.24.7-2.0-1.9-1.7-2.2-1.0-0.4-1.4-1.6-0.7-0.9
One hour access (shock baseline)0.20.31.60.4-0.2-0.20.3-0.1-0.70.1-0.41.2-0.5
Social response proportion0.30.30.70.20.90.50.60.30.30.40.4-0.80.8
Social responses0.50.61.30.21.20.80.60.90.71.01.0-0.50.1
Social time1.21.74.8-2.2-1.6-1.1-1.6-0.6-0.4-0.9-1.0-0.1-1.7
Soleus weight0.51.44.0-2.00.8-1.4-1.4-0.9-1.3-0.2-1.1-0.91.0
Bone: stiffness0.91.42.51.30.61.31.21.31.60.91.1-1.40.7
Tibialis anterior weight0.10.51.40.80.10.50.41.20.90.80.3-0.6-0.4
Time to tail flick, vehicle, before self-admin0.60.61.8-0.4-1.00.4-0.30.61.10.50.3-1.1-1.3
Time to tail flick, vehicle, after self-admin0.30.40.7-0.8-0.1-0.7-0.6-0.8-0.7-0.7-0.60.6-0.1
Time to tail flick, test, before self-admin0.60.63.3-0.0-0.80.50.20.80.60.80.40.2-1.8
Time to tail flick, test, after self-admin2.12.24.1-1.5-1.6-1.3-1.3-1.1-1.3-1.2-1.31.9-2.0
Delta time to tail flick, vehicle, before/after SA1.31.33.5-0.3-0.1-1.1-0.5-1.5-1.6-1.3-0.91.90.4
Delta time to tail flick, test, before/after SA0.50.50.9-0.4-0.8-0.8-0.8-0.9-0.7-0.9-0.80.5-0.4
Tibia length0.41.12.5-0.21.30.80.61.10.91.50.9-1.60.9
Ambulatory time before self-admin0.10.10.4-0.2-0.5-0.4-0.5-0.20.1-0.6-0.2-0.3-0.1
Ambulatory time after self-admin0.50.61.30.40.70.90.81.11.00.70.9-0.80.1
Bone: tissue strength0.30.31.60.50.80.40.6-0.1-0.00.20.1-0.31.3
Total heroin consumption0.10.10.7-0.4-0.10.2-0.20.00.3-0.00.6-0.0-0.8
Bone: trabecular number1.11.85.6-0.7-2.4-1.1-1.2-1.2-0.7-1.5-1.01.0-1.7
Bone: trabecular spacing2.02.67.91.12.81.51.61.30.91.61.5-0.92.0
Bone: trabecular thickness1.11.35.2-0.6-2.3-1.1-1.2-0.7-0.4-1.1-1.00.4-1.4
Bone: trabecular tissue density0.10.21.1-0.30.6-0.1-0.0-0.1-0.6-0.0-0.31.00.2
Water consumed over 24 hours0.10.10.2-0.50.1-0.4-0.4-0.2-0.2-0.2-0.30.00.0
Number of responses in last shaping day0.60.61.6-0.60.6-1.0-0.5-0.5-1.3-0.7-0.80.21.2