Hub : Genes

Gfod2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio NM_001107421.1 0.06 0.04 1.1e-04 0.04 0.02 0.01 0.04 6.0e-05 1.0e-02 1.7e-02 1.6e-04
2 Adipose gene expression Gfod2 0.05 0.03 1.2e-07 0.05 0.05 0.05 0.05 2.9e-06 4.3e-06 6.8e-06 4.1e-06
3 Brain isoform ratio XM_063278026.1 0.04 0.03 9.3e-04 0.02 0.02 0.01 0.01 2.7e-03 7.6e-03 1.5e-02 1.2e-02
4 NAcc gene expression Gfod2 0.02 0.02 1.7e-04 0.03 0.02 0.01 0.02 5.9e-05 1.3e-04 7.9e-03 2.5e-04
5 Brain alternative polyA XM_063278026.1 0.09 0.07 2.0e-05 0.04 0.03 0.02 0.05 2.0e-04 1.4e-03 6.0e-03 3.8e-05
6 Liver isoform ratio XM_063278027.1 0.02 0.01 3.5e-03 0 0 -0 0 9.5e-02 9.3e-02 7.3e-01 1.2e-01
7 Brain alternative polyA NM_001107421.1 0.08 0.06 2.4e-05 0.04 0.03 0.02 0.04 3.3e-04 1.4e-03 4.5e-03 4.5e-05
8 pVTA alternative polyA XM_063278026.1 0.04 0.03 6.4e-04 0.01 0.03 0.02 0.02 4.0e-02 2.9e-03 1.7e-02 1.5e-02
9 pVTA alternative polyA NM_001107421.1 0.04 0.03 7.6e-04 0.01 0.03 0.01 0.01 4.5e-02 3.2e-03 2.2e-02 1.9e-02
10 PL alternative polyA NM_001107421.1 0.03 0.02 4.9e-04 0.03 0.02 0.02 0.02 5.2e-04 2.4e-03 1.2e-03 1.0e-03
11 PL alternative polyA XM_063278026.1 0.03 0.02 5.1e-04 0.03 0.02 0.02 0.02 5.4e-04 2.7e-03 1.1e-03 9.8e-04
12 Adipose isoform ratio XM_039097734.2 0.02 0.02 8.7e-03 0.01 0 0.01 0 3.5e-02 8.2e-02 6.0e-02 1.4e-01
13 Liver alternative TSS XM_063278029.1 0.05 0.03 4.4e-03 0.02 0.01 0.02 0.02 3.4e-03 1.3e-02 6.5e-03 5.1e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density0.10.10.3-0.5-0.50.5-0.30.4-0.4-0.30.3-0.3-0.20.2-0.1-0.1
Area under the delay curve0.00.00.1-0.00.0-0.00.3-0.00.00.00.1-0.1-0.00.00.4-0.3
BMI with tail0.10.21.0-0.5-0.5-0.1-0.40.4-0.3-0.30.4-0.4-0.40.40.81.0
BMI without tail0.00.10.40.10.1-0.60.2-0.10.20.1-0.00.0-0.40.40.50.6
Body weight0.31.22.6-1.1-1.11.1-0.81.2-1.0-1.00.9-0.9-1.21.20.61.6
Weight adjusted by age0.00.00.20.10.00.0-0.30.0-0.1-0.10.0-0.0-0.10.1-0.3-0.4
Bone surface1.12.03.0-1.7-1.71.7-1.41.7-1.6-1.41.4-1.4-1.31.30.80.3
Bone volume0.91.62.5-1.6-1.61.4-1.11.5-1.5-1.31.3-1.3-1.31.30.4-0.4
Breakpoint value in progressive ratio session1.72.03.11.61.5-1.11.2-1.51.41.5-1.51.51.5-1.5-1.8-0.0
Number of licking bursts0.71.13.3-1.2-1.31.1-1.01.1-0.8-1.00.7-0.6-0.80.80.71.8
Context. condit. distance diff. score0.10.20.80.40.4-0.20.4-0.20.20.3-0.40.40.5-0.5-0.90.2
Locomotion velocity, session 10.10.10.8-0.1-0.10.1-0.20.1-0.1-0.10.3-0.3-0.20.20.90.5
Locomotion distance, session 10.10.20.70.40.3-0.40.4-0.40.50.4-0.50.50.1-0.1-0.30.9
Locomotion velocity, session 21.11.32.31.31.2-1.01.1-1.01.20.9-1.31.30.6-0.6-1.31.5
Locomotion distance, session 20.40.53.40.60.6-0.50.6-0.40.70.4-0.70.80.1-0.1-0.61.9
Locomotion velocity, session 30.20.20.40.40.3-0.50.4-0.50.60.5-0.50.50.7-0.7-0.00.6
Locomotion distance, session 30.10.10.50.20.1-0.10.3-0.10.20.2-0.30.30.3-0.3-0.7-0.1
Stereotopy head waving bouts, day 30.20.20.6-0.6-0.60.4-0.50.4-0.3-0.30.4-0.4-0.50.50.8-0.2
Stereotopy head waving duration, day 30.60.71.1-1.1-1.00.9-0.90.9-0.7-0.80.7-0.7-0.90.90.80.5
Locomotion velocity, session 70.20.22.10.40.3-0.20.2-0.1-0.10.10.1-0.10.3-0.3-0.4-1.5
Locomotion distance, session 70.10.21.50.30.2-0.20.2-0.20.10.2-0.20.20.3-0.3-0.6-1.2
Stereotopy head waving bouts, day 70.30.30.9-0.9-0.90.6-0.60.6-0.5-0.50.5-0.5-0.20.20.60.3
Stereotopy head waving duration, day 70.80.91.8-1.3-1.21.0-1.11.0-0.8-0.80.9-0.9-0.60.61.30.5
Locomotion velocity, session 80.20.21.90.20.2-0.00.1-0.10.20.1-0.20.20.3-0.30.01.4
Locomotion distance, session 80.71.01.81.11.0-0.80.9-0.80.90.8-1.01.10.9-0.9-1.11.3
Degree of sensitization distance0.10.11.5-0.1-0.10.1-0.10.1-0.2-0.10.3-0.3-0.10.10.1-1.2
Degree of sensitization stereotypy0.40.40.8-0.9-0.90.7-0.70.7-0.6-0.60.7-0.7-0.40.40.80.0
Conditioned locomotion1.61.92.7-1.3-1.31.5-1.41.5-1.4-1.61.2-1.2-1.71.70.51.0
Cocaine response after cond. corrected0.91.03.2-0.6-0.50.5-0.90.7-0.9-0.71.3-1.3-0.60.61.7-1.8
Cocaine response after cond. not corrected0.30.41.9-0.2-0.00.1-0.40.1-0.3-0.10.7-0.70.0-0.01.4-1.3
Cocaine response before conditioning1.21.51.91.01.0-1.01.1-1.21.41.2-1.41.41.3-1.3-0.81.3
Saline control response3.95.27.9-2.1-2.12.2-2.32.3-2.2-2.42.1-2.1-2.82.81.92.1
Bone: connectivity density0.00.10.2-0.1-0.10.00.1-0.10.20.2-0.30.30.3-0.3-0.40.4
Bone: cortical apparent density0.50.71.60.40.3-1.00.4-0.80.80.7-0.70.71.3-1.3-0.3-1.1
Bone: cortical area0.40.62.2-0.6-0.70.5-0.50.7-0.9-0.60.8-0.8-0.60.60.2-1.5
Bone: cortical porosity0.50.51.01.00.9-0.71.0-0.60.50.8-0.70.70.3-0.3-1.00.2
Bone: cortical porosity0.40.40.80.90.9-0.70.9-0.60.50.7-0.50.50.4-0.4-0.7-0.2
Bone: cortical thickness0.20.31.5-0.4-0.50.3-0.40.5-0.6-0.40.6-0.6-0.40.40.3-1.2
Bone: cortical thickness0.30.31.90.10.1-0.20.50.2-0.10.2-0.10.1-0.20.2-1.3-1.4
Bone: cortical tissue density0.50.71.70.40.4-1.00.4-0.90.90.7-0.80.81.3-1.3-0.3-1.1
Condit. Reinf. active minus inactive responses3.84.25.42.32.3-2.32.2-2.11.92.1-1.81.82.2-2.2-1.5-1.7
Condit. Reinf. active-inactive response ratio3.43.64.92.22.2-2.12.0-2.01.82.0-1.71.62.2-2.2-1.2-1.4
Condit. Reinf. active responses2.73.44.42.12.0-2.12.0-1.91.81.9-1.71.71.8-1.8-1.6-1.3
Condit. Reinf. inactive responses0.20.20.60.20.2-0.50.5-0.40.40.5-0.50.50.4-0.4-0.8-0.6
Incentive salience index mean2.12.64.12.02.0-1.81.7-1.71.51.6-1.41.41.6-1.6-1.2-1.1
Condit. Reinf. lever presses0.20.31.01.00.9-0.60.6-0.50.40.4-0.40.40.3-0.3-0.3-0.1
Condit. Reinf. active minus inactive responses0.70.91.5-1.1-1.20.6-1.01.1-1.0-1.01.0-1.0-0.90.90.6-0.4
Condit. Reinf. active-inactive response ratio0.80.92.0-1.3-1.40.7-0.91.0-0.9-0.91.0-1.0-0.70.70.7-0.7
Condit. Reinf. active responses0.30.40.6-0.5-0.60.2-0.60.8-0.7-0.80.6-0.6-0.80.80.10.2
Condit. Reinf. inactive responses0.30.41.11.11.0-0.80.7-0.60.50.4-0.60.60.1-0.1-0.80.4
Condit. Reinf. lever presses2.94.17.21.81.7-1.92.0-1.82.01.8-2.32.31.7-1.7-2.72.2
Condit. Reinf. lever reinforcers received0.00.10.2-0.1-0.2-0.3-0.10.3-0.2-0.30.0-0.0-0.30.3-0.50.4
Conditioned reinforcement - actives0.71.22.41.41.4-1.51.4-1.21.11.2-0.90.90.7-0.7-0.3-0.6
Conditioned reinforcement - inactives0.20.30.7-0.5-0.50.3-0.70.4-0.5-0.30.6-0.60.3-0.30.8-0.7
Conditioned locomotion0.60.81.2-0.9-1.00.8-0.90.9-1.1-0.91.1-1.1-0.60.61.0-0.2
Patch foraging indifference point 0 sec2.54.65.9-2.1-2.22.3-2.22.3-2.2-2.42.1-2.1-2.42.41.60.7
Patch foraging indifference point AUC1.42.12.8-1.7-1.61.5-1.31.6-1.4-1.51.1-1.1-1.71.70.51.6
Delay disc. indifference point, 0s delay0.50.50.80.70.8-0.80.9-0.80.90.8-0.70.70.7-0.7-0.10.5
Delay disc. indifference point, 16s delay0.20.20.5-0.3-0.20.20.30.3-0.3-0.30.4-0.4-0.70.70.6-0.6
Delay disc. indifference point, 2s delay0.20.30.5-0.7-0.60.6-0.30.6-0.5-0.50.6-0.5-0.00.00.60.3
Delay disc. indifference point, 24s delay0.00.00.1-0.3-0.20.10.40.10.0-0.1-0.00.0-0.20.20.00.2
Delay disc. indifference point, 4s delay0.20.20.50.30.3-0.3-0.1-0.40.40.3-0.30.30.7-0.7-0.3-0.4
Delay disc. indifference point, 8s delay0.10.11.1-0.0-0.0-0.00.2-0.1-0.10.00.2-0.3-0.00.00.3-1.0
Indifference point function ln k0.30.63.60.70.6-0.60.5-0.60.40.6-0.10.10.8-0.80.2-1.9
Indifference point function log k0.30.63.60.70.6-0.60.5-0.60.40.6-0.10.10.8-0.80.2-1.9
Patch foraging total patch changes 0 sec2.44.56.0-2.1-2.12.3-2.22.3-2.2-2.42.1-2.1-2.52.51.50.6
Patch foraging total patch changes 12 sec2.63.44.5-2.0-2.02.1-1.82.0-1.7-2.01.5-1.4-2.12.10.91.8
Patch foraging total patch changes 18 sec2.03.14.7-1.9-1.82.0-1.52.0-2.0-1.91.7-1.7-2.22.20.4-0.2
Patch foraging total patch changes 24 sec0.50.97.2-0.9-0.81.1-0.60.8-0.4-0.70.1-0.1-0.40.4-0.52.7
Patch foraging total patch changes 6 sec1.82.74.1-1.6-1.61.9-1.81.7-1.6-1.91.4-1.4-1.71.71.02.0
Patch foraging time to switch 0 sec0.71.41.81.31.3-1.01.1-1.21.31.2-1.31.31.3-1.3-0.80.7
Patch foraging water rate 0 sec1.32.63.8-1.7-1.81.8-1.51.7-1.7-1.71.6-1.6-2.02.01.3-0.1
Patch foraging water rate 12 sec0.10.31.0-0.6-0.71.0-0.50.5-0.5-0.50.5-0.4-0.40.4-0.0-0.3
Patch foraging water rate 18 sec0.10.20.7-0.6-0.60.9-0.40.3-0.3-0.30.2-0.10.2-0.2-0.8-0.1
Patch foraging water rate 24 sec0.10.21.6-0.2-0.20.40.10.0-0.2-0.00.3-0.3-0.40.4-0.2-1.3
Patch foraging water rate 6 sec0.91.33.3-1.4-1.31.3-1.01.1-1.3-1.01.1-1.1-0.80.80.0-1.8
Seeking ratio, delayed vs. immediate footshock2.43.04.5-1.8-1.81.7-1.71.7-1.9-1.72.0-2.0-1.51.52.1-0.6
Distance traveled before self-admin0.91.22.3-1.5-1.51.2-1.41.3-1.3-1.00.9-0.90.3-0.3-0.6-1.1
Distance traveled after self-admin0.20.20.7-0.8-0.70.5-0.80.5-0.4-0.40.3-0.3-0.00.00.2-0.1
Extensor digitorum longus weight0.93.57.82.12.0-1.52.2-1.81.71.9-2.02.01.5-1.5-2.8-0.1
Bone: elastic displacement2.02.33.0-1.5-1.51.4-1.51.3-1.6-1.31.7-1.7-1.31.31.5-1.7
Bone: elastic work0.91.23.9-1.0-1.10.8-1.00.8-1.1-0.91.2-1.2-0.80.80.8-2.0
Bone: endosteal estimation0.10.20.8-0.3-0.30.2-0.30.2-0.4-0.30.4-0.4-0.40.40.1-0.9
Bone: endosteal perimeter0.10.20.4-0.3-0.40.3-0.20.5-0.6-0.40.5-0.5-0.50.5-0.1-0.6
Epididymis fat weight1.75.78.1-2.5-2.62.8-2.12.6-2.8-2.52.5-2.5-2.52.51.2-1.0
Delta time in closed arm before/after self-admin0.20.20.6-0.3-0.30.40.10.3-0.2-0.30.3-0.4-0.50.50.70.2
Delta time in open arm before/after self-admin0.20.20.90.0-0.00.1-0.8-0.0-0.10.10.1-0.10.9-0.9-0.2-0.8
Diff in mean of infusions in LGA sessions0.60.81.50.70.8-0.41.0-0.70.80.8-1.01.00.9-0.9-1.21.1
Delay discount exponential model param0.00.00.1-0.0-0.10.1-0.30.1-0.1-0.10.0-0.0-0.10.1-0.20.0
Extinction: sum of active levers before priming0.70.81.11.01.1-1.10.7-1.00.90.9-0.90.90.8-0.8-0.8-0.1
Active lever presses in extinction session 60.10.10.30.10.1-0.20.00.0-0.1-0.10.1-0.2-0.30.30.1-0.6
Bone: final force0.91.52.71.41.3-1.31.4-1.21.11.2-1.21.21.0-1.0-1.6-0.7
Bone: final moment0.40.61.01.00.9-0.80.8-0.90.70.8-0.70.70.6-0.6-1.0-0.8
Food consumed during 24 hour testing period0.10.20.4-0.4-0.40.4-0.20.4-0.3-0.50.1-0.1-0.60.6-0.50.3
Glucose1.01.62.61.21.2-1.40.7-1.51.51.3-1.31.31.6-1.6-0.6-0.2
Heart weight0.00.00.2-0.2-0.3-0.20.0-0.00.10.10.0-0.10.1-0.10.4-0.1
Delay discount hyperbolic model param0.00.00.1-0.1-0.10.2-0.40.2-0.2-0.20.1-0.1-0.20.2-0.2-0.0
Intermittent access intake day 1-15 change1.02.03.71.41.5-1.91.2-1.61.71.5-1.61.61.2-1.2-1.10.1
Intermittent access intake escalation1.12.23.81.51.5-1.91.3-1.71.71.6-1.61.61.3-1.3-1.00.2
Intermittent access intake escalation 20.80.91.81.01.0-1.30.8-1.11.21.0-1.01.00.8-0.8-0.4-0.2
Intermitt. access day 1 inactive lever presses0.10.21.90.20.3-0.40.1-0.20.40.1-0.20.20.0-0.00.71.4
Intermitt. access day 15 inactive lever presses0.10.20.80.10.1-0.20.4-0.30.20.4-0.20.20.9-0.9-0.1-0.4
Intermitt. access escalation Index0.30.51.1-0.8-0.81.1-0.80.6-0.6-0.70.6-0.6-0.60.60.90.0
Intermittent access day 1 total infusions0.20.32.20.70.5-0.50.4-0.40.30.30.1-0.1-0.20.21.50.2
Intermittent access day 15 total infusions1.42.14.61.91.8-2.21.3-1.81.71.6-1.31.31.1-1.10.2-0.2
Intermittent access terminal intake (last 3 days)2.53.36.02.42.2-2.41.8-2.22.01.9-1.71.71.5-1.5-0.3-0.3
Intermittent access total infusions2.12.55.02.22.0-2.11.8-1.91.71.7-1.31.31.1-1.1-0.1-0.6
Intermittent access day 1 locomotion1.41.86.3-0.9-1.01.0-1.21.0-1.2-1.21.6-1.6-1.41.42.5-0.3
Intermittent access day 15 total locomotion0.30.63.1-0.6-0.70.2-0.80.5-0.6-0.60.9-1.0-0.60.61.8-0.4
Intermittent access total locomotion0.40.53.40.1-0.1-0.2-0.20.0-0.4-0.20.8-0.8-0.30.31.9-1.1
Intermittent access standard deviation0.10.30.8-0.4-0.40.4-0.90.5-0.6-0.40.6-0.7-0.40.40.8-0.4
Left kidney weight1.88.216.52.22.2-2.22.9-2.52.82.8-3.33.33.1-3.1-4.11.9
Right kidney weight1.98.518.92.32.3-2.43.1-2.52.82.8-3.33.43.0-3.0-4.31.8
Cocaine induced anxiety2.63.75.4-2.3-2.21.8-2.02.0-1.9-1.92.0-2.0-1.81.82.00.4
Post-drug Anxiety0.70.81.6-1.2-1.10.9-0.90.9-0.7-0.80.8-0.8-0.70.71.00.7
Baseline Anxiety1.41.62.11.41.3-1.21.3-1.41.51.4-1.41.41.3-1.3-0.90.2
Tail length0.00.10.50.30.30.10.7-0.10.10.1-0.20.2-0.50.5-0.20.7
Length with tail0.10.62.1-0.4-0.41.3-0.20.7-0.6-0.50.3-0.3-0.90.9-0.51.4
Length without tail0.41.22.5-1.1-1.11.6-1.21.2-1.2-1.20.9-0.9-1.11.10.21.2
Times rat made contact with spout1.31.52.0-1.4-1.41.3-1.21.3-1.2-1.31.1-1.1-1.41.41.00.3
Lifetime Intake1.72.14.32.11.9-1.81.7-1.81.51.5-1.21.20.9-0.9-0.1-0.7
Liver weight, left0.30.62.0-0.9-0.91.0-0.70.7-0.5-0.60.3-0.3-0.60.60.31.4
Liver weight, right0.40.72.7-0.8-0.71.1-0.30.8-0.7-0.70.5-0.5-1.01.00.11.6
Locomotor activity2.23.54.8-1.8-1.91.9-1.92.0-2.2-2.12.0-2.0-2.12.11.0-0.7
Locomotor testing distance1.93.45.3-1.7-1.81.6-1.72.0-2.0-1.92.0-2.0-2.32.31.5-0.6
Locomotor testing rearing0.30.51.1-0.8-0.80.5-0.40.8-0.9-0.60.7-0.7-0.90.9-0.1-1.0
Locomotion in novel chamber2.12.73.7-1.7-1.71.5-1.71.7-1.8-1.61.9-1.9-1.41.41.9-0.7
Locomotion in novel chamber post-restriction1.82.94.6-1.7-1.81.4-1.41.7-1.6-1.71.7-1.8-2.12.11.7-0.9
Fecal boli incidents, locomotor time 11.01.43.8-1.1-1.11.0-1.41.1-0.8-1.20.7-0.7-2.02.00.41.0
Change in fecal boli incidents, locomotor task0.70.71.50.70.7-0.70.5-0.80.80.8-0.80.81.1-1.1-0.31.2
Time >=10cm from walls, locomotor time 10.50.51.6-0.5-0.50.6-0.60.5-0.4-0.60.5-0.5-1.31.30.60.7
Bouts of movement, locomotor time 10.20.21.0-0.4-0.30.2-0.40.3-0.1-0.30.2-0.2-0.50.50.91.0
Total resting periods, locomotor time 10.10.10.8-0.1-0.1-0.1-0.3-0.00.2-0.0-0.00.0-0.10.10.70.9
Rest time, locomotor task time 10.20.32.00.40.4-0.50.0-0.40.50.3-0.30.30.2-0.20.81.4
Distance moved, locomotor task time 10.20.31.5-0.5-0.60.4-0.20.4-0.5-0.30.5-0.5-0.00.0-0.0-1.2
Vertical activity count, locomotor time 10.51.34.3-1.2-1.31.1-0.71.1-1.2-1.01.1-1.1-1.01.0-0.0-2.1
Time >=10cm from walls, locomotor time 20.20.30.50.60.7-0.70.3-0.70.70.7-0.60.60.3-0.3-0.60.0
Bouts of movement, locomotor time 20.50.81.60.80.9-1.01.3-0.91.00.9-0.90.90.9-0.9-0.50.2
Total resting periods, locomotor time 20.61.01.71.01.0-1.11.3-1.11.11.1-1.11.11.0-1.0-0.70.5
Rest time, locomotor task time 20.50.61.10.90.9-0.90.5-1.01.10.8-0.90.90.2-0.2-0.21.0
Distance moved, locomotor task time 20.91.14.2-1.1-1.11.0-1.01.0-1.2-0.81.2-1.2-0.20.20.4-2.0
Vertical activity count, locomotor time 21.11.52.5-1.5-1.51.3-1.01.4-1.4-1.21.3-1.3-0.80.80.4-1.6
Light reinforcement 11.84.56.1-2.3-2.32.4-2.02.4-2.5-2.32.2-2.2-2.22.21.1-0.7
Light reinforcement 22.23.54.8-2.1-2.21.9-2.02.0-2.0-2.01.9-1.9-1.81.81.3-0.5
Bone: marrow area0.10.10.9-0.2-0.20.1-0.30.1-0.4-0.30.4-0.4-0.40.40.1-0.9
Bone: maximum diameter0.30.71.2-0.7-0.70.4-0.70.8-1.0-0.90.9-0.9-0.80.80.6-1.1
Bone: maximum force0.20.40.80.60.5-0.60.7-0.70.50.7-0.60.60.7-0.7-0.9-0.6
Bone: maximum moment0.00.10.60.20.1-0.10.2-0.30.10.2-0.10.10.3-0.3-0.2-0.7
Mean time between licks in bursts0.10.22.3-0.3-0.20.1-0.10.2-0.3-0.10.2-0.20.3-0.3-0.2-1.5
Mean num. licks in bursts0.20.22.80.10.2-0.20.2-0.1-0.10.10.1-0.1-0.20.2-0.2-1.7
Cd content in liver0.10.10.30.40.4-0.30.5-0.30.10.4-0.10.10.5-0.5-0.3-0.5
Co content in liver0.20.32.80.40.4-0.30.3-0.30.10.2-0.00.00.1-0.1-0.4-1.7
Cu content in liver1.01.22.31.31.3-0.71.5-1.11.11.2-1.11.10.8-0.8-1.10.2
Fe content in liver2.02.53.5-1.5-1.51.7-1.71.6-1.6-1.71.6-1.6-1.91.91.3-0.7
K content in liver0.10.10.40.50.5-0.60.1-0.40.40.2-0.30.30.3-0.3-0.10.1
Mg content in liver0.40.40.5-0.7-0.70.6-0.70.6-0.5-0.70.6-0.6-0.70.70.70.7
Mn content in liver0.80.91.9-1.3-1.40.9-1.01.0-0.9-0.90.9-0.9-0.70.71.00.1
Na content in liver0.10.11.0-0.10.00.0-1.0-0.00.0-0.30.1-0.2-0.10.10.5-0.7
Rb content in liver0.30.41.60.60.6-0.31.3-0.50.60.8-0.50.50.4-0.4-0.40.1
Se content in liver0.60.77.8-0.1-0.1-0.10.6-0.2-0.00.40.0-0.00.2-0.2-0.7-2.8
Sr content in liver0.90.81.4-0.9-0.91.2-0.71.0-0.9-0.90.8-0.8-0.90.90.80.6
Zn content in liver2.12.33.21.71.6-1.71.8-1.51.31.5-1.31.31.3-1.3-1.6-1.6
Bone: minimum diameter0.20.42.7-0.4-0.50.2-0.40.4-0.7-0.40.7-0.7-0.50.50.3-1.6
Time in familiar zone, hab. session 10.50.41.3-0.8-0.70.6-0.70.5-0.6-0.40.7-0.7-0.20.20.7-1.1
Time in novel zone, hab. session 10.20.20.40.70.6-0.60.5-0.40.50.4-0.50.50.2-0.2-0.4-0.1
Total zone transitions, hab. session 10.81.12.0-0.9-0.91.0-0.91.1-0.9-1.10.8-0.8-1.31.30.91.4
Total locomotion distance, hab. session 10.91.32.2-1.0-1.11.2-1.01.3-1.1-1.31.0-1.0-1.51.50.60.7
Locomotion velocity, hab. session 11.11.62.8-1.1-1.11.3-1.11.4-1.2-1.41.0-1.0-1.71.70.71.4
Time in familiar zone, hab. session 21.51.64.2-1.2-1.20.9-1.11.1-1.2-1.01.4-1.5-0.70.71.7-2.0
Time in novel zone, hab. session 23.94.05.11.91.9-2.12.1-2.12.22.1-2.32.31.9-1.9-2.00.7
Total zone transitions, hab. session 21.92.44.1-1.4-1.41.5-1.41.7-1.4-1.71.2-1.2-1.91.91.02.0
Total locomotion distance, hab. session 20.91.22.4-0.9-0.91.1-0.91.3-1.1-1.30.9-0.9-1.51.50.50.8
Locomotion velocity, hab. session 20.91.22.3-0.8-0.91.1-0.81.2-1.0-1.30.8-0.8-1.51.50.31.4
Novel to familiar place preference ratio1.61.83.70.91.0-1.31.2-1.41.51.6-1.31.31.9-1.9-0.60.5
Novelty place preference2.52.75.11.31.3-1.71.5-1.81.81.9-1.61.62.3-2.3-0.80.4
Time in novel zone, NPP test2.32.44.61.21.3-1.61.5-1.71.71.8-1.51.52.1-2.1-0.7-0.0
Total zone transitions, NPP test1.52.23.5-1.4-1.41.6-1.41.6-1.4-1.71.3-1.2-1.91.90.91.3
Total locomotion distance, NPP test0.81.12.2-0.9-1.01.1-0.81.2-1.0-1.20.7-0.7-1.51.50.11.0
Locomotion velocity, NPP test0.60.91.9-0.8-0.81.0-0.71.1-0.9-1.10.6-0.6-1.41.4-0.11.1
Intraocular pressure0.60.91.91.01.1-0.81.4-0.80.70.8-0.80.90.8-0.8-1.4-0.4
Delta distance traveled before/after self-admin0.50.51.40.60.7-0.60.5-0.70.80.7-0.70.70.6-0.60.01.2
Delta ambulatory time before/after self-admin0.70.91.51.11.1-1.10.8-1.11.21.0-1.00.90.5-0.5-0.01.2
Parametrial fat weight6.615.520.2-4.3-4.44.5-4.34.1-4.0-4.03.9-3.9-4.14.13.5-0.2
Pavlov. Cond. lever latency0.20.31.4-0.6-0.50.2-0.40.2-0.3-0.10.5-0.5-0.00.01.0-1.2
Pavlov. Cond. magazine entry latency0.91.12.71.51.5-1.01.2-0.90.90.8-1.11.10.5-0.5-1.60.0
Pavlov. Cond. change in total contacts0.91.01.31.11.1-0.91.0-0.91.00.8-1.11.10.8-0.8-1.11.0
Pavlov. Cond. index score0.81.12.81.31.3-0.81.0-0.70.80.6-1.11.10.4-0.4-1.71.3
Pavlov. Cond. latency score0.70.92.31.21.2-0.70.9-0.60.70.5-1.01.00.3-0.3-1.51.1
Pavlov. Cond. lever contacts0.91.02.11.21.2-0.81.0-0.80.90.7-1.11.10.6-0.6-1.41.3
Pavlov. Cond. magazine entry number0.91.12.4-1.4-1.41.0-1.21.0-1.0-0.81.1-1.1-0.50.51.6-0.1
Pavlov. Cond. intertrial magazine entries0.60.75.7-0.4-0.50.3-0.40.4-0.7-0.40.8-0.8-0.40.40.5-2.4
Pavlov. Cond. lever-magazine prob. diff.0.91.12.81.31.3-0.81.0-0.70.90.6-1.11.20.4-0.4-1.71.4
Pavlov. Cond. response bias0.60.71.81.11.1-0.70.9-0.60.70.5-0.90.90.3-0.3-1.30.8
Pavlov. Cond. lever latency1.41.93.7-1.0-1.01.5-1.51.2-1.4-1.31.6-1.6-1.21.21.9-0.9
Pavlov. Cond. magazine entry latency3.44.15.92.12.1-2.42.2-2.02.02.0-2.12.12.0-2.0-2.1-0.5
Pavlov. Cond. change in total contacts1.82.97.11.41.4-1.71.9-1.51.61.6-1.91.91.6-1.6-2.7-0.1
Pavlov. Cond. index score3.34.46.52.02.0-2.42.3-2.02.22.1-2.32.32.0-2.0-2.50.4
Pavlov. Cond. latency score3.44.55.92.02.0-2.42.3-2.02.22.1-2.32.32.1-2.1-2.40.7
Pavlov. Cond. lever contacts1.82.45.21.31.2-1.71.7-1.41.61.5-1.81.81.3-1.3-2.30.9
Pavlov. Cond. magazine entry number5.26.48.5-2.6-2.62.9-2.72.5-2.5-2.62.6-2.6-2.62.62.70.5
Pavlov. Cond. intertrial magazine entries4.16.18.3-2.6-2.62.2-2.52.6-2.6-2.72.6-2.6-2.92.91.8-0.9
Pavlov. Cond. lever-magazine prob. diff.3.74.96.92.12.1-2.62.4-2.22.32.2-2.42.42.2-2.2-2.50.1
Pavlov. Cond. response bias3.04.17.41.81.8-2.32.2-1.92.02.0-2.22.22.0-2.0-2.70.1
Time in closed arm before self-admin2.83.64.5-2.0-2.01.8-2.12.0-1.7-2.11.6-1.6-1.91.91.62.1
Time in closed arm after self-admin3.23.44.6-2.1-2.01.9-1.82.0-1.7-1.91.6-1.6-1.81.81.81.9
Time in open arm before self-admin2.02.24.91.61.5-1.31.7-1.41.31.5-1.51.51.2-1.2-2.2-0.9
Time in open arm after self-admin1.01.14.71.10.9-0.70.3-0.90.60.9-0.60.61.2-1.2-1.2-2.2
Bone: periosteal estimation0.30.62.4-0.7-0.70.5-0.60.6-0.9-0.70.8-0.8-0.70.70.1-1.5
Bone: periosteal perimeter0.50.91.4-1.0-1.10.9-0.71.1-1.2-0.91.1-1.0-1.01.00.3-0.8
Bone: post-yield work0.60.91.5-1.1-1.11.2-1.00.9-1.0-0.81.1-1.1-0.70.71.20.1
Progressive ratio test 1 active lever presses3.03.76.72.52.3-2.32.6-2.21.92.0-1.81.71.5-1.5-1.1-0.9
Progressive ratio test 1 breakpoint2.73.36.02.32.2-2.22.5-2.01.81.9-1.71.61.4-1.4-1.1-0.9
Progressive ratio test 1 inactive lever presses0.10.10.60.40.4-0.70.3-0.40.30.2-0.10.1-0.20.20.70.1
Progressive ratio test 2 active lever presses2.12.44.72.22.0-2.11.7-1.91.81.6-1.41.40.8-0.8-0.2-0.3
Progressive ratio test 2 breakpoint2.22.54.82.22.1-2.21.8-1.91.81.7-1.51.50.8-0.8-0.3-0.2
Progressive ratio test 2 inactive lever presses0.20.31.10.50.4-0.60.4-0.50.30.40.0-0.00.3-0.30.8-1.1
Incentive Sensitization - Responses0.60.91.91.31.2-1.40.8-1.21.21.0-0.90.90.2-0.20.20.6
Incentive Sensitization - Breakpoint0.81.02.21.41.3-1.50.9-1.31.31.1-1.01.00.2-0.20.20.6
Sum of active levers in priming session hrs 5-60.40.40.70.60.6-0.60.7-0.60.40.6-0.30.30.8-0.8-0.4-0.6
Progressive ratio0.20.32.3-0.2-0.20.20.60.2-0.20.1-0.20.30.7-0.7-1.50.4
Food seeking constrained by brief footshock1.92.44.71.51.6-1.11.1-1.41.51.3-1.71.71.6-1.6-2.21.2
Seeking ratio, punishment vs. effort0.50.71.31.11.1-0.80.2-1.01.10.8-0.90.90.7-0.7-0.20.6
Retroperitoneal fat weight6.126.231.4-5.5-5.65.3-5.35.4-5.5-5.25.5-5.5-5.05.04.6-1.6
Reaction time number correct1.01.93.01.51.6-1.71.6-1.51.51.6-1.41.31.2-1.2-0.8-0.0
Reaction time mean minus median0.71.82.81.61.7-1.31.6-1.21.01.4-1.21.21.4-1.4-1.5-0.2
Reaction time mean minus median AUC0.61.52.61.51.6-1.11.6-1.10.91.3-1.11.11.2-1.2-1.60.1
Reaction time num false alarms0.10.20.30.40.4-0.20.4-0.50.40.6-0.30.30.5-0.50.00.6
Reaction time num false alarms AUC0.00.10.50.10.20.10.1-0.10.10.20.0-0.0-0.10.10.30.7
Reaction time trials correct on left1.01.93.01.51.6-1.71.6-1.51.51.6-1.41.31.2-1.2-0.8-0.0
Reaction time trials on left1.12.03.21.51.6-1.81.7-1.51.51.6-1.41.41.2-1.2-0.9-0.1
Reaction time mean0.10.20.90.20.20.00.3-0.1-0.00.3-0.20.21.0-1.0-0.9-0.1
Reaction time mean AUC0.30.41.40.40.5-0.20.5-0.40.30.6-0.40.51.2-1.2-0.90.1
Median of all reaction times0.10.10.4-0.3-0.30.5-0.20.3-0.4-0.10.2-0.20.7-0.7-0.50.0
Reaction time omissions0.10.10.4-0.10.1-0.10.30.2-0.2-0.00.0-0.0-0.60.6-0.4-0.2
Reaction time false alarm rate0.30.40.8-0.6-0.60.9-0.70.6-0.7-0.60.7-0.7-0.60.60.70.5
Reaction time premature initiation rate1.21.72.71.41.4-1.11.1-1.31.31.2-1.41.41.4-1.4-1.6-0.0
Reaction time premature initiations2.23.94.72.22.2-2.01.9-2.12.02.0-2.12.12.0-2.0-2.0-0.1
Std. dev. reaction times0.30.51.10.80.9-0.70.7-0.60.30.7-0.50.51.0-1.0-1.0-0.3
Reaction time trials completed1.12.03.21.51.6-1.81.7-1.51.51.6-1.41.41.2-1.2-0.9-0.1
Reaction time trials AUC1.01.93.11.51.6-1.81.7-1.51.51.6-1.41.41.2-1.2-0.9-0.2
Run reversals in cocaine runway, females1.71.73.0-1.1-1.20.7-1.71.2-1.3-1.41.3-1.3-1.61.61.0-0.7
Run reversals in cocaine runway, males0.50.51.6-0.6-0.60.5-0.80.6-0.5-0.70.4-0.4-1.21.20.2-0.2
Latency to leave start box in cocaine runway0.10.20.50.20.2-0.2-0.0-0.40.40.4-0.40.30.7-0.70.00.1
Latency to leave start box in cocaine runway, F0.80.91.91.11.1-1.40.5-1.21.21.1-0.80.81.0-1.00.5-0.1
Latency to leave start box in cocaine runway, M1.00.92.8-1.2-1.21.7-0.91.2-1.1-1.00.8-0.7-0.30.3-0.30.4
Std. dev. time between licks in bursts1.62.13.0-1.7-1.71.6-1.51.7-1.7-1.61.5-1.5-1.51.50.6-0.5
Total sessions with >9 infusions1.51.93.81.81.7-1.71.7-1.51.31.3-1.01.00.7-0.7-0.6-1.9
Short access day 1 total inactive lever presses0.20.32.70.00.0-0.1-0.20.0-0.2-0.10.4-0.4-0.30.30.8-1.6
Short access day 10 total inactive lever presses0.10.30.5-0.6-0.60.3-0.50.5-0.5-0.50.5-0.5-0.70.70.60.7
Short access day 1 total infusions0.40.51.51.21.1-0.80.8-0.90.70.6-0.40.3-0.10.10.3-1.1
Short access day 10 total infusions0.40.51.41.21.0-0.81.1-0.90.70.7-0.40.30.1-0.10.6-0.5
Short access total infusions1.72.14.32.11.9-1.62.0-1.71.51.5-1.21.20.9-0.9-0.2-1.1
Short access day 1 locomotion0.20.30.70.80.7-0.80.4-0.60.50.3-0.40.4-0.20.2-0.3-0.6
Short access day 10 total locomotion1.73.15.9-1.4-1.61.5-1.31.6-1.9-1.72.2-2.2-1.61.62.4-1.6
Short access total locomotion0.60.72.3-0.2-0.30.6-0.40.5-0.7-0.71.0-1.0-0.60.61.5-1.4
One hour access (0.3 mA shock)1.21.32.81.61.6-1.71.4-1.41.31.2-1.11.00.5-0.50.00.4
Compulsive drug intake0.20.20.6-0.6-0.50.4-0.80.5-0.4-0.50.2-0.2-0.40.4-0.4-0.0
One hour access (shock baseline)1.01.63.11.81.7-1.71.5-1.51.41.4-1.01.00.7-0.70.50.2
Social response proportion0.60.71.51.21.2-0.90.9-0.90.90.9-0.60.60.7-0.7-0.0-0.7
Social responses0.10.10.60.40.5-0.20.2-0.10.10.10.0-0.0-0.10.1-0.1-0.8
Social time0.20.32.80.50.6-0.40.4-0.30.00.30.1-0.20.0-0.00.1-1.7
Soleus weight0.20.50.9-0.4-0.50.9-0.90.6-0.8-0.90.7-0.7-0.70.70.2-0.4
Bone: stiffness3.25.16.92.32.2-2.32.5-2.22.32.4-2.42.42.3-2.3-2.60.4
Tibialis anterior weight0.51.63.91.61.6-0.71.6-1.01.01.1-1.31.30.5-0.5-2.01.1
Time to tail flick, vehicle, before self-admin0.40.51.11.11.1-0.90.3-0.90.80.8-0.60.60.2-0.2-0.2-0.2
Time to tail flick, vehicle, after self-admin1.01.33.4-0.8-0.80.6-0.60.9-1.0-0.91.3-1.3-1.51.51.9-1.1
Time to tail flick, test, before self-admin2.72.84.2-1.5-1.62.0-1.21.7-1.6-1.71.5-1.5-2.12.11.61.5
Time to tail flick, test, after self-admin0.20.20.9-0.2-0.20.20.20.3-0.3-0.30.4-0.4-0.40.40.8-1.0
Delta time to tail flick, vehicle, before/after SA1.31.23.9-0.8-0.80.50.00.9-1.0-0.91.2-1.2-1.31.31.2-2.0
Delta time to tail flick, test, before/after SA1.11.12.41.01.0-1.21.0-1.11.01.0-0.90.91.1-1.1-0.9-1.6
Tibia length0.10.10.70.0-0.0-0.40.3-0.20.30.2-0.40.40.1-0.1-0.60.9
Ambulatory time before self-admin1.11.73.1-1.8-1.71.5-1.71.5-1.6-1.31.2-1.2-0.30.3-0.2-1.2
Ambulatory time after self-admin0.40.51.8-1.1-1.00.8-1.30.8-0.7-0.70.5-0.5-0.20.20.10.0
Bone: tissue strength0.20.21.30.10.1-0.1-0.2-0.50.40.2-0.00.00.6-0.61.2-0.2
Total heroin consumption0.91.01.91.41.3-0.90.7-1.21.11.1-1.01.01.1-1.1-0.40.1
Bone: trabecular number0.30.51.1-1.0-1.10.7-0.70.9-0.7-0.70.7-0.7-0.50.50.30.1
Bone: trabecular spacing0.00.10.2-0.1-0.10.3-0.20.1-0.2-0.20.2-0.2-0.40.40.3-0.2
Bone: trabecular thickness0.50.61.00.70.6-0.80.9-0.70.70.8-0.80.80.8-0.8-1.0-0.1
Bone: trabecular tissue density0.60.91.11.01.1-0.90.8-1.01.10.9-1.01.01.0-1.0-0.50.7
Water consumed over 24 hours0.30.41.5-0.6-0.70.7-0.50.6-0.4-0.60.3-0.3-0.70.70.21.2
Number of responses in last shaping day0.91.02.60.70.8-0.70.6-0.80.70.8-0.90.91.4-1.4-1.60.0