Hub : Genes

Gcnt4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Gcnt4 0.52 0.12 0.0e+00 0.33 0.36 0.37 0.36 4.9e-38 2.9e-41 1.8e-42 3.8e-42
2 pVTA gene expression Gcnt4 0.06 0.05 6.7e-04 0.04 0.03 0.03 0.04 2.1e-04 4.0e-03 2.4e-03 5.0e-04
3 Brain isoform ratio XM_039103468.2 0.09 0.05 1.0e-11 0.12 0.13 0.13 0.13 1.4e-11 2.6e-12 6.8e-12 8.6e-12
4 Adipose alternative TSS XM_039103467.2 0.06 0.04 5.4e-04 0 0.01 0.01 0 3.2e-01 7.3e-03 9.1e-03 8.7e-02
5 Liver isoform ratio NM_001399789.1 0.05 0.04 6.5e-03 0 0.01 0.01 0.01 1.5e-01 2.1e-02 2.2e-02 2.3e-02
6 Brain intron excision ratio chr2_29988943_30012956 0.05 0.04 2.1e-05 0.04 0.04 0.02 0.03 1.3e-04 8.7e-05 6.6e-03 1.6e-03
7 OFC isoform ratio XM_039103468.2 0.15 0.12 7.1e-03 0.04 0.04 0.03 -0 3.3e-02 4.0e-02 7.5e-02 3.6e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.20.40.10.40.5-0.4-0.40.3
Area under the delay curve0.60.71.0-0.81.0-0.9-0.80.50.9-0.7
BMI with tail1.65.46.8-2.61.9-2.4-2.52.42.4-2.0
BMI without tail1.65.06.0-2.42.3-2.2-2.32.32.2-1.7
Body weight1.98.310.2-3.03.2-3.1-2.72.32.9-2.9
Weight adjusted by age0.20.31.0-0.5-0.70.2-0.51.00.1-0.2
Bone surface0.00.10.5-0.10.7-0.00.2-0.2-0.10.1
Bone volume0.20.40.60.60.00.60.8-0.7-0.70.6
Breakpoint value in progressive ratio session0.00.00.10.2-0.20.20.3-0.2-0.1-0.1
Number of licking bursts0.00.00.00.1-0.20.0-0.10.00.1-0.2
Context. condit. distance diff. score1.21.41.81.2-1.31.31.0-0.9-1.21.4
Locomotion velocity, session 10.30.30.50.7-0.10.70.6-0.6-0.60.3
Locomotion distance, session 11.01.21.61.3-0.81.21.2-1.2-1.20.9
Locomotion velocity, session 20.10.10.30.20.60.20.3-0.2-0.2-0.1
Locomotion distance, session 21.01.31.91.4-1.01.41.1-1.1-1.20.9
Locomotion velocity, session 31.01.22.01.0-0.61.40.9-0.6-1.31.4
Locomotion distance, session 31.11.22.21.0-0.81.30.8-0.8-1.31.5
Stereotopy head waving bouts, day 31.61.92.61.6-0.91.41.5-1.5-1.41.0
Stereotopy head waving duration, day 30.10.10.20.30.30.00.5-0.4-0.1-0.3
Locomotion velocity, session 70.30.40.70.3-0.80.70.2-0.0-0.60.9
Locomotion distance, session 70.10.10.2-0.30.4-0.1-0.30.30.2-0.2
Stereotopy head waving bouts, day 72.73.04.01.6-1.71.91.5-1.4-1.92.0
Stereotopy head waving duration, day 70.60.81.10.8-0.91.00.8-0.6-1.01.0
Locomotion velocity, session 82.22.63.41.8-1.61.81.6-1.3-1.71.4
Locomotion distance, session 80.91.32.01.1-1.21.40.9-0.7-1.31.4
Degree of sensitization distance0.90.92.0-0.70.6-1.1-0.80.71.1-1.4
Degree of sensitization stereotypy1.82.03.61.1-1.41.61.1-0.9-1.61.9
Conditioned locomotion0.20.20.50.2-0.30.40.4-0.5-0.50.7
Cocaine response after cond. corrected0.40.51.0-0.81.0-0.5-0.60.80.5-0.3
Cocaine response after cond. not corrected0.91.11.4-1.21.2-0.9-1.11.21.0-0.8
Cocaine response before conditioning0.10.10.2-0.2-0.2-0.2-0.50.30.3-0.1
Saline control response0.60.81.3-1.10.4-0.9-1.01.00.9-0.7
Bone: connectivity density0.00.10.10.20.20.20.3-0.3-0.20.1
Bone: cortical apparent density2.53.45.21.6-2.12.01.4-1.2-1.92.3
Bone: cortical area0.30.51.80.5-1.30.40.5-0.5-0.50.7
Bone: cortical porosity0.00.00.10.3-0.10.20.2-0.3-0.20.1
Bone: cortical porosity0.20.30.50.6-0.70.50.4-0.5-0.40.4
Bone: cortical thickness1.22.05.51.1-2.31.20.9-0.8-1.21.6
Bone: cortical thickness0.50.61.0-1.00.4-0.8-1.00.80.7-0.4
Bone: cortical tissue density2.43.34.91.7-2.02.01.4-1.2-1.92.2
Condit. Reinf. active minus inactive responses0.10.20.3-0.5-0.10.1-0.50.6-0.10.6
Condit. Reinf. active-inactive response ratio0.30.30.9-0.8-0.2-0.2-0.71.00.20.3
Condit. Reinf. active responses0.10.10.3-0.50.2-0.1-0.50.4-0.00.4
Condit. Reinf. inactive responses0.10.10.4-0.20.6-0.3-0.20.10.2-0.2
Incentive salience index mean0.20.30.6-0.70.7-0.4-0.70.50.20.1
Condit. Reinf. lever presses0.10.10.40.00.7-0.00.1-0.5-0.20.2
Condit. Reinf. active minus inactive responses0.30.41.2-0.5-0.5-0.3-1.01.10.5-0.1
Condit. Reinf. active-inactive response ratio0.50.61.1-0.6-0.0-0.7-1.01.00.9-0.8
Condit. Reinf. active responses0.20.20.6-0.2-0.80.1-0.60.80.10.3
Condit. Reinf. inactive responses0.20.30.6-0.70.3-0.3-0.70.80.4-0.2
Condit. Reinf. lever presses0.10.10.2-0.2-0.4-0.1-0.50.50.20.1
Condit. Reinf. lever reinforcers received0.20.30.7-0.3-0.7-0.0-0.70.80.20.2
Conditioned reinforcement - actives0.50.91.4-0.80.7-1.0-0.91.11.0-1.2
Conditioned reinforcement - inactives0.10.10.20.5-0.40.20.2-0.4-0.20.3
Conditioned locomotion0.50.70.91.0-0.70.80.9-0.8-0.80.8
Patch foraging indifference point 0 sec0.91.73.0-1.51.7-1.3-1.10.91.2-1.1
Patch foraging indifference point AUC0.50.71.4-0.50.8-1.0-0.80.51.0-1.2
Delay disc. indifference point, 0s delay0.10.10.2-0.1-0.40.1-0.20.2-0.10.5
Delay disc. indifference point, 16s delay0.10.10.2-0.30.4-0.4-0.2-0.00.4-0.3
Delay disc. indifference point, 2s delay0.10.10.2-0.30.1-0.3-0.40.30.3-0.1
Delay disc. indifference point, 24s delay2.52.84.6-1.72.1-1.7-1.51.31.6-1.7
Delay disc. indifference point, 4s delay0.10.10.5-0.00.7-0.1-0.2-0.00.00.5
Delay disc. indifference point, 8s delay1.82.12.6-1.51.6-1.5-1.31.11.4-1.6
Indifference point function ln k0.00.00.0-0.10.00.20.10.1-0.20.2
Indifference point function log k0.00.00.0-0.10.00.20.10.1-0.20.2
Patch foraging total patch changes 0 sec0.81.63.0-1.41.7-1.3-1.00.91.1-1.2
Patch foraging total patch changes 12 sec1.41.82.1-1.41.3-1.5-1.31.11.4-1.4
Patch foraging total patch changes 18 sec0.81.31.7-1.00.5-1.2-1.31.11.3-1.2
Patch foraging total patch changes 24 sec1.72.93.5-1.81.3-1.9-1.81.61.9-1.5
Patch foraging total patch changes 6 sec1.42.13.5-1.61.9-1.5-1.11.01.4-1.5
Patch foraging time to switch 0 sec0.00.10.4-0.4-0.2-0.0-0.30.60.10.0
Patch foraging water rate 0 sec0.10.20.70.20.40.10.5-0.8-0.30.1
Patch foraging water rate 12 sec0.61.32.70.8-1.31.20.8-0.8-1.11.6
Patch foraging water rate 18 sec0.30.50.9-0.90.1-0.7-1.00.80.8-0.2
Patch foraging water rate 24 sec0.50.71.5-1.01.2-0.8-0.70.50.7-0.7
Patch foraging water rate 6 sec1.42.03.41.6-1.31.21.4-1.8-1.31.1
Seeking ratio, delayed vs. immediate footshock0.10.10.30.10.60.00.0-0.4-0.20.2
Distance traveled before self-admin0.10.10.3-0.30.1-0.5-0.50.20.5-0.0
Distance traveled after self-admin1.92.43.2-1.71.8-1.6-1.61.31.5-1.1
Extensor digitorum longus weight0.00.10.20.00.4-0.10.3-0.4-0.0-0.4
Bone: elastic displacement1.31.52.61.6-1.61.01.2-1.2-0.90.4
Bone: elastic work0.70.91.71.3-0.80.71.2-1.3-0.70.2
Bone: endosteal estimation0.40.91.8-0.91.3-1.0-0.80.60.9-0.9
Bone: endosteal perimeter0.10.30.4-0.60.6-0.6-0.50.40.5-0.4
Epididymis fat weight1.86.37.8-2.82.2-2.5-2.72.62.5-2.2
Delta time in closed arm before/after self-admin1.31.21.71.2-1.31.01.0-1.1-1.01.2
Delta time in open arm before/after self-admin1.11.12.4-1.40.1-0.8-1.41.50.9-0.6
Diff in mean of infusions in LGA sessions0.70.91.31.1-0.80.81.2-1.1-0.80.7
Delay discount exponential model param0.70.81.20.9-1.11.00.8-0.6-0.90.7
Extinction: sum of active levers before priming0.10.10.2-0.4-0.20.0-0.30.40.10.3
Active lever presses in extinction session 60.20.20.60.40.30.40.6-0.8-0.50.3
Bone: final force0.00.10.3-0.1-0.5-0.2-0.20.20.2-0.2
Bone: final moment0.00.10.2-0.2-0.4-0.3-0.10.20.2-0.2
Food consumed during 24 hour testing period1.62.24.6-1.70.4-1.2-2.02.21.3-0.4
Glucose0.91.53.41.3-1.91.30.8-0.5-1.11.3
Heart weight1.72.73.7-1.81.2-1.5-1.81.91.6-1.3
Delay discount hyperbolic model param0.50.61.00.7-1.00.80.8-0.5-0.80.5
Intermittent access intake day 1-15 change0.20.41.10.6-1.00.40.4-0.5-0.40.6
Intermittent access intake escalation0.30.61.20.8-1.10.60.5-0.7-0.50.9
Intermittent access intake escalation 20.20.20.60.5-0.80.30.4-0.4-0.30.5
Intermitt. access day 1 inactive lever presses1.35.07.42.2-2.22.02.0-2.2-2.12.7
Intermitt. access day 15 inactive lever presses1.73.54.71.9-2.21.81.5-1.7-1.82.1
Intermitt. access escalation Index0.20.30.40.6-0.60.60.5-0.6-0.60.5
Intermittent access day 1 total infusions1.52.53.2-1.61.3-1.8-1.81.41.8-1.3
Intermittent access day 15 total infusions0.20.30.7-0.5-0.1-0.6-0.80.60.7-0.1
Intermittent access terminal intake (last 3 days)0.10.20.4-0.3-0.3-0.4-0.60.50.5-0.2
Intermittent access total infusions0.70.81.3-0.90.4-1.0-1.20.91.0-0.6
Intermittent access day 1 locomotion0.40.50.9-0.60.6-1.0-0.80.50.8-0.6
Intermittent access day 15 total locomotion1.01.82.5-1.20.6-1.6-1.41.31.6-1.3
Intermittent access total locomotion0.10.10.3-0.1-0.0-0.5-0.40.10.4-0.1
Intermittent access standard deviation0.10.20.60.3-0.70.30.0-0.2-0.30.8
Left kidney weight4.822.426.9-5.25.1-4.8-4.64.34.7-4.3
Right kidney weight5.524.928.3-5.34.8-5.1-5.14.85.0-4.7
Cocaine induced anxiety0.10.10.20.20.10.50.5-0.0-0.4-0.3
Post-drug Anxiety0.20.20.5-0.40.7-0.1-0.10.60.2-0.7
Baseline Anxiety0.10.10.2-0.20.4-0.4-0.40.20.4-0.1
Tail length0.83.07.1-1.72.7-1.7-1.31.21.5-1.6
Length with tail1.14.69.1-2.13.0-2.2-1.51.32.0-2.4
Length without tail0.92.84.2-1.72.0-1.8-1.30.91.6-2.1
Times rat made contact with spout3.23.66.6-2.21.1-1.6-2.42.61.8-1.2
Lifetime Intake0.50.61.0-0.80.5-0.9-1.00.70.9-0.5
Liver weight, left5.69.210.9-3.32.6-3.0-3.33.13.0-2.8
Liver weight, right1.52.75.3-1.92.3-1.6-1.51.11.4-1.3
Locomotor activity0.20.41.3-0.5-0.3-0.1-0.71.10.4-0.5
Locomotor testing distance1.93.47.9-2.00.7-1.3-2.22.81.7-1.5
Locomotor testing rearing1.02.15.4-1.70.5-0.9-1.72.31.2-0.8
Locomotion in novel chamber0.40.60.90.7-0.81.00.7-0.4-0.80.7
Locomotion in novel chamber post-restriction0.30.41.00.61.00.20.6-0.9-0.40.4
Fecal boli incidents, locomotor time 10.10.20.30.5-0.40.00.4-0.5-0.1-0.5
Change in fecal boli incidents, locomotor task0.20.20.40.40.10.50.3-0.1-0.50.6
Time >=10cm from walls, locomotor time 12.42.54.71.8-0.91.31.9-2.2-1.51.0
Bouts of movement, locomotor time 10.60.71.6-0.90.4-0.7-0.91.30.8-0.7
Total resting periods, locomotor time 10.80.91.6-1.00.6-0.8-0.91.30.9-1.0
Rest time, locomotor task time 10.20.20.40.4-0.50.60.4-0.1-0.50.4
Distance moved, locomotor task time 10.30.51.0-1.00.8-0.8-0.80.40.7-0.2
Vertical activity count, locomotor time 10.10.20.5-0.60.7-0.5-0.50.10.30.0
Time >=10cm from walls, locomotor time 20.10.10.10.30.40.20.2-0.3-0.30.3
Bouts of movement, locomotor time 20.10.10.20.40.10.30.2-0.1-0.40.4
Total resting periods, locomotor time 20.10.10.20.4-0.20.40.2-0.2-0.50.4
Rest time, locomotor task time 20.30.42.30.3-1.50.40.10.0-0.30.5
Distance moved, locomotor task time 20.60.81.5-1.11.2-0.7-0.90.90.6-0.2
Vertical activity count, locomotor time 20.20.30.8-0.70.9-0.4-0.60.50.20.2
Light reinforcement 11.02.42.8-1.61.6-1.4-1.41.71.5-1.6
Light reinforcement 20.00.10.2-0.20.4-0.4-0.2-0.10.3-0.2
Bone: marrow area0.40.91.7-0.91.3-1.0-0.80.60.9-0.9
Bone: maximum diameter0.30.61.0-0.80.5-1.0-0.70.60.9-0.7
Bone: maximum force0.10.30.4-0.6-0.1-0.5-0.60.70.5-0.4
Bone: maximum moment0.10.20.3-0.6-0.0-0.6-0.50.60.5-0.4
Mean time between licks in bursts0.61.52.8-1.00.8-1.4-1.01.01.4-1.7
Mean num. licks in bursts0.81.32.6-1.40.7-1.0-1.41.61.0-0.5
Cd content in liver0.10.10.3-0.3-0.6-0.0-0.40.50.10.4
Co content in liver0.60.71.3-1.10.9-0.6-0.91.10.5-0.2
Cu content in liver0.20.20.40.4-0.30.40.4-0.4-0.40.6
Fe content in liver1.11.42.01.2-0.81.11.3-1.4-1.21.0
K content in liver0.80.81.7-1.01.3-0.8-0.80.70.7-0.5
Mg content in liver0.40.40.80.6-0.90.50.4-0.5-0.50.8
Mn content in liver2.83.13.91.7-1.71.81.7-1.6-1.82.0
Na content in liver0.60.61.1-0.81.1-0.8-0.50.50.7-0.9
Rb content in liver0.20.20.4-0.5-0.1-0.5-0.70.50.5-0.1
Se content in liver2.12.53.51.4-1.31.71.5-1.5-1.81.9
Sr content in liver0.10.10.2-0.00.50.10.4-0.4-0.30.1
Zn content in liver0.10.10.20.2-0.20.30.3-0.4-0.40.4
Bone: minimum diameter1.22.34.61.5-2.11.41.3-1.2-1.41.5
Time in familiar zone, hab. session 10.00.00.10.3-0.2-0.0-0.0-0.20.1-0.2
Time in novel zone, hab. session 12.22.23.2-1.81.4-1.4-1.41.71.4-1.2
Total zone transitions, hab. session 10.91.21.71.1-0.51.21.1-1.3-1.31.1
Total locomotion distance, hab. session 10.91.32.21.3-0.61.01.3-1.5-1.10.8
Locomotion velocity, hab. session 11.72.53.91.8-1.01.51.8-2.0-1.61.3
Time in familiar zone, hab. session 21.51.61.9-1.31.0-1.3-1.31.21.4-1.3
Time in novel zone, hab. session 20.10.10.10.10.10.30.10.1-0.30.3
Total zone transitions, hab. session 20.10.10.3-0.00.6-0.0-0.0-0.10.1-0.4
Total locomotion distance, hab. session 20.10.20.30.5-0.50.50.3-0.3-0.40.3
Locomotion velocity, hab. session 20.10.10.30.5-0.30.40.3-0.4-0.40.3
Novel to familiar place preference ratio0.30.30.70.3-0.70.60.4-0.2-0.60.8
Novelty place preference0.20.20.60.2-0.50.60.3-0.1-0.60.8
Time in novel zone, NPP test0.30.30.70.3-0.60.70.4-0.2-0.70.9
Total zone transitions, NPP test0.60.91.21.1-0.31.01.0-1.1-1.00.8
Total locomotion distance, NPP test1.92.63.41.8-1.51.71.6-1.6-1.61.4
Locomotion velocity, NPP test1.62.33.01.7-1.41.51.5-1.6-1.51.4
Intraocular pressure4.97.09.12.6-2.13.02.6-2.3-3.02.8
Delta distance traveled before/after self-admin1.61.72.6-1.51.6-1.3-1.21.21.2-1.1
Delta ambulatory time before/after self-admin1.82.32.9-1.71.6-1.4-1.51.51.4-1.4
Parametrial fat weight0.00.10.2-0.40.4-0.3-0.30.20.3-0.3
Pavlov. Cond. lever latency0.10.10.5-0.1-0.70.2-0.10.4-0.10.2
Pavlov. Cond. magazine entry latency2.32.96.0-1.72.5-1.7-1.21.21.5-1.8
Pavlov. Cond. change in total contacts0.40.51.4-0.71.2-0.6-0.50.40.5-0.6
Pavlov. Cond. index score1.01.33.3-1.11.8-1.2-0.80.61.0-1.2
Pavlov. Cond. latency score0.81.02.4-0.81.6-1.0-0.60.50.9-1.1
Pavlov. Cond. lever contacts0.10.20.50.40.30.20.5-0.7-0.30.2
Pavlov. Cond. magazine entry number4.96.110.22.7-3.22.42.1-2.1-2.32.4
Pavlov. Cond. intertrial magazine entries0.80.91.31.0-1.00.90.8-0.9-0.91.1
Pavlov. Cond. lever-magazine prob. diff.0.70.92.7-0.81.7-0.9-0.50.40.7-0.9
Pavlov. Cond. response bias1.92.35.7-1.62.4-1.5-1.21.01.3-1.4
Pavlov. Cond. lever latency0.10.10.20.3-0.00.10.4-0.4-0.1-0.3
Pavlov. Cond. magazine entry latency4.55.46.9-2.61.9-2.3-2.62.62.3-1.9
Pavlov. Cond. change in total contacts0.10.20.4-0.4-0.1-0.4-0.60.60.5-0.3
Pavlov. Cond. index score1.41.92.9-1.60.9-1.3-1.71.71.3-0.9
Pavlov. Cond. latency score1.92.53.7-1.81.1-1.5-1.91.91.5-1.0
Pavlov. Cond. lever contacts0.10.10.2-0.3-0.2-0.1-0.50.50.10.3
Pavlov. Cond. magazine entry number3.44.25.82.3-1.32.02.4-2.4-2.11.6
Pavlov. Cond. intertrial magazine entries0.50.81.51.2-1.00.81.0-1.0-0.70.3
Pavlov. Cond. lever-magazine prob. diff.1.72.33.7-1.70.9-1.4-1.91.91.5-1.0
Pavlov. Cond. response bias0.30.40.8-0.80.1-0.5-0.90.90.5-0.2
Time in closed arm before self-admin0.91.11.71.2-0.70.91.1-1.3-1.01.1
Time in closed arm after self-admin1.71.92.41.6-1.31.21.3-1.4-1.21.5
Time in open arm before self-admin2.83.14.7-1.71.7-1.8-1.61.51.8-2.2
Time in open arm after self-admin4.24.76.3-2.51.9-1.9-2.32.42.0-2.0
Bone: periosteal estimation0.00.00.1-0.1-0.2-0.2-0.0-0.10.10.0
Bone: periosteal perimeter0.00.10.1-0.1-0.3-0.3-0.0-0.00.3-0.3
Bone: post-yield work0.20.30.8-0.60.9-0.6-0.30.30.5-0.7
Progressive ratio test 1 active lever presses0.20.20.4-0.30.2-0.6-0.60.30.6-0.4
Progressive ratio test 1 breakpoint0.10.10.3-0.20.1-0.5-0.60.20.5-0.3
Progressive ratio test 1 inactive lever presses0.10.10.40.50.10.20.3-0.7-0.30.2
Progressive ratio test 2 active lever presses1.92.23.0-1.51.0-1.6-1.71.51.7-1.3
Progressive ratio test 2 breakpoint1.72.02.8-1.40.9-1.5-1.71.41.6-1.2
Progressive ratio test 2 inactive lever presses0.30.50.6-0.70.6-0.7-0.80.80.8-0.6
Incentive Sensitization - Responses3.14.35.5-2.21.6-2.0-2.22.32.1-1.9
Incentive Sensitization - Breakpoint3.14.15.3-2.11.6-2.0-2.22.32.1-1.8
Sum of active levers in priming session hrs 5-60.00.00.1-0.20.40.00.20.2-0.00.2
Progressive ratio0.40.61.4-1.00.4-0.5-0.91.20.6-0.2
Food seeking constrained by brief footshock1.41.72.1-1.21.3-1.3-1.21.41.3-1.5
Seeking ratio, punishment vs. effort0.10.10.60.20.5-0.30.1-0.20.2-0.8
Retroperitoneal fat weight0.62.53.5-1.81.2-1.6-1.91.71.7-0.9
Reaction time number correct0.81.63.01.0-1.01.31.1-1.2-1.31.7
Reaction time mean minus median0.10.10.70.5-0.90.2-0.00.1-0.00.1
Reaction time mean minus median AUC0.10.20.4-0.1-0.5-0.4-0.60.60.5-0.4
Reaction time num false alarms0.30.40.7-0.70.4-0.8-0.70.60.8-0.5
Reaction time num false alarms AUC0.40.71.0-0.80.5-1.0-0.90.61.0-0.8
Reaction time trials correct on left0.81.63.01.0-1.01.31.1-1.2-1.31.7
Reaction time trials on left1.01.83.41.1-1.21.41.1-1.2-1.41.8
Reaction time mean0.71.14.40.9-2.11.00.3-0.0-0.71.0
Reaction time mean AUC0.50.93.50.9-1.90.80.3-0.1-0.60.9
Median of all reaction times0.60.83.60.7-1.90.80.20.1-0.60.9
Reaction time omissions1.11.74.91.0-2.21.30.30.1-1.01.7
Reaction time false alarm rate1.42.02.8-1.31.1-1.6-1.31.21.6-1.7
Reaction time premature initiation rate3.44.75.5-2.12.0-2.2-2.02.22.3-2.3
Reaction time premature initiations0.71.21.5-1.21.0-1.1-1.11.21.2-0.9
Std. dev. reaction times0.40.82.91.0-1.70.80.3-0.2-0.50.7
Reaction time trials completed1.01.83.41.1-1.21.41.1-1.2-1.41.8
Reaction time trials AUC0.91.73.31.0-1.21.41.0-1.1-1.41.8
Run reversals in cocaine runway, females0.40.40.80.9-0.70.40.6-0.8-0.3-0.2
Run reversals in cocaine runway, males0.70.71.31.0-0.50.71.0-1.1-0.80.7
Latency to leave start box in cocaine runway0.70.81.61.2-0.30.60.9-1.3-0.80.5
Latency to leave start box in cocaine runway, F0.30.41.10.70.10.30.7-1.0-0.50.2
Latency to leave start box in cocaine runway, M0.30.30.70.9-0.70.50.4-0.4-0.40.3
Std. dev. time between licks in bursts1.31.72.6-1.21.5-1.5-1.10.81.4-1.6
Total sessions with >9 infusions0.10.20.3-0.40.4-0.5-0.50.30.5-0.0
Short access day 1 total inactive lever presses0.10.10.2-0.10.3-0.4-0.40.10.4-0.1
Short access day 10 total inactive lever presses0.51.31.71.2-0.61.11.3-1.3-1.21.2
Short access day 1 total infusions0.00.00.10.00.1-0.2-0.1-0.30.10.3
Short access day 10 total infusions0.10.10.30.2-0.6-0.1-0.2-0.10.10.4
Short access total infusions0.10.10.3-0.30.3-0.5-0.50.10.5-0.2
Short access day 1 locomotion0.10.10.40.2-0.20.10.0-0.3-0.10.7
Short access day 10 total locomotion4.48.112.02.9-2.82.62.4-2.9-2.73.5
Short access total locomotion1.72.13.41.5-1.41.21.2-1.6-1.31.8
One hour access (0.3 mA shock)0.20.20.3-0.50.4-0.6-0.50.40.5-0.4
Compulsive drug intake0.10.10.2-0.20.4-0.3-0.2-0.00.2-0.3
One hour access (shock baseline)0.00.10.1-0.3-0.1-0.3-0.30.30.3-0.1
Social response proportion7.88.811.63.4-3.22.92.8-2.9-2.92.6
Social responses2.12.63.61.8-1.91.71.4-1.3-1.61.7
Social time0.71.01.31.0-0.81.11.0-0.8-1.11.1
Soleus weight0.20.51.7-0.01.3-0.40.5-0.80.1-0.7
Bone: stiffness0.40.71.3-1.10.5-0.8-0.91.00.7-0.3
Tibialis anterior weight3.211.013.03.6-2.83.33.5-3.6-3.42.9
Time to tail flick, vehicle, before self-admin0.00.00.2-0.10.2-0.2-0.0-0.30.10.4
Time to tail flick, vehicle, after self-admin0.20.20.4-0.50.2-0.6-0.60.50.5-0.1
Time to tail flick, test, before self-admin0.40.41.50.6-1.20.40.3-0.4-0.40.5
Time to tail flick, test, after self-admin1.01.01.51.0-0.91.21.0-1.0-1.20.9
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.1-0.1-0.0-0.20.50.1-0.4
Delta time to tail flick, test, before/after SA0.50.50.80.60.20.70.9-0.9-0.80.4
Tibia length0.30.91.2-1.00.5-1.1-0.90.91.1-1.0
Ambulatory time before self-admin0.10.20.4-0.40.2-0.6-0.50.20.5-0.1
Ambulatory time after self-admin1.21.42.0-1.41.2-1.3-1.41.01.2-0.7
Bone: tissue strength0.10.10.2-0.2-0.2-0.3-0.30.40.3-0.2
Total heroin consumption0.30.40.80.6-0.90.40.7-0.6-0.40.4
Bone: trabecular number0.00.00.1-0.10.3-0.10.0-0.00.0-0.1
Bone: trabecular spacing0.30.41.50.5-1.20.60.1-0.1-0.40.8
Bone: trabecular thickness2.83.44.92.1-1.31.82.2-2.2-1.81.3
Bone: trabecular tissue density0.20.30.70.4-0.30.70.3-0.2-0.60.8
Water consumed over 24 hours2.94.07.0-2.41.2-1.7-2.52.61.8-1.1
Number of responses in last shaping day0.10.10.3-0.20.5-0.0-0.2-0.1-0.10.5