Hub : Genes

Gabrg2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL mRNA stability Gabrg2 0.25 0.16 7.0e-06 0.22 0.23 0.24 0.25 4.2e-06 2.3e-06 1.4e-06 1.2e-06
2 NAcc mRNA stability Gabrg2 0.28 0.11 0.0e+00 0.34 0.34 0.34 0.35 2.5e-41 4.2e-41 5.1e-40 6.2e-42
3 BLA mRNA stability Gabrg2 0.53 0.11 0.0e+00 0.44 0.47 0.43 0.46 1.0e-25 6.5e-28 9.4e-25 5.2e-27
4 Brain mRNA stability Gabrg2 0.35 0.13 0.0e+00 0.41 0.38 0.41 0.3 1.1e-40 6.9e-37 1.3e-40 7.4e-28
5 RMTg gene expression Gabrg2 0.18 0.13 5.8e-04 0.08 0.08 0.06 0.06 4.2e-03 4.5e-03 9.0e-03 9.3e-03
6 LHb mRNA stability Gabrg2 0.46 0.17 9.1e-13 0.39 0.47 0.45 0.46 2.4e-10 1.1e-12 3.4e-12 1.8e-12
7 PL mRNA stability Gabrg2 0.25 0.09 0.0e+00 0.38 0.38 0.38 0.38 1.5e-43 7.0e-44 1.9e-43 2.4e-43
8 pVTA gene expression Gabrg2 0.06 0.05 6.3e-03 0.01 0.02 0.01 0.01 7.5e-02 3.9e-02 1.2e-01 1.0e-01
9 NAcc gene expression Gabrg2 0.05 0.04 2.7e-06 0.04 0.05 0.04 0.04 4.5e-05 3.6e-06 5.5e-06 7.1e-06
10 pVTA mRNA stability Gabrg2 0.56 0.13 0.0e+00 0.56 0.58 0.57 0.58 1.9e-28 1.1e-30 7.7e-30 2.8e-30
11 OFC mRNA stability Gabrg2 0.6 0.2 3.5e-10 0.33 0.34 0.35 0.35 1.4e-08 6.0e-09 3.7e-09 3.3e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.11.82.51.61.31.4-1.3-1.11.41.31.4-1.41.31.1
Area under the delay curve2.72.94.1-2.0-1.6-1.71.51.5-1.7-1.6-1.82.0-1.6-1.5
BMI with tail0.10.30.5-0.3-0.7-0.60.70.5-0.4-0.6-0.3-0.0-0.6-0.6
BMI without tail0.00.10.20.1-0.4-0.40.4-0.3-0.2-0.3-0.20.0-0.30.2
Body weight1.45.98.22.92.22.2-2.2-2.82.32.22.4-2.62.22.7
Weight adjusted by age0.10.10.40.6-0.0-0.00.10.10.2-0.00.3-0.50.00.2
Bone surface0.30.61.81.30.60.7-0.6-0.60.70.70.8-0.80.70.6
Bone volume2.03.35.82.41.71.8-1.6-1.61.81.71.9-2.01.71.7
Breakpoint value in progressive ratio session0.70.81.60.70.80.9-0.9-1.30.80.90.8-0.80.81.1
Number of licking bursts0.40.40.70.90.60.7-0.6-0.50.70.60.7-0.70.60.6
Context. condit. distance diff. score0.91.12.21.51.00.8-0.9-1.01.01.01.1-1.21.01.2
Locomotion velocity, session 10.10.10.1-0.4-0.3-0.30.40.2-0.2-0.3-0.20.1-0.3-0.2
Locomotion distance, session 10.00.00.10.0-0.00.10.1-0.10.20.00.2-0.30.00.1
Locomotion velocity, session 20.20.20.7-0.6-0.3-0.20.20.8-0.3-0.3-0.30.4-0.3-0.7
Locomotion distance, session 20.00.00.1-0.1-0.10.10.00.30.1-0.10.0-0.1-0.0-0.3
Locomotion velocity, session 30.00.00.00.2-0.1-0.10.2-0.1-0.1-0.2-0.10.1-0.20.0
Locomotion distance, session 30.00.00.3-0.6-0.00.00.10.2-0.1-0.1-0.20.2-0.1-0.2
Stereotopy head waving bouts, day 30.10.10.2-0.3-0.1-0.20.20.4-0.2-0.2-0.30.4-0.2-0.3
Stereotopy head waving duration, day 30.10.10.10.00.40.3-0.3-0.00.30.30.2-0.10.30.1
Locomotion velocity, session 71.92.12.61.61.51.4-1.4-1.41.41.51.4-1.41.51.5
Locomotion distance, session 70.91.11.30.81.11.1-1.1-0.91.11.11.1-1.01.11.0
Stereotopy head waving bouts, day 71.61.82.60.91.61.6-1.5-0.81.41.41.4-1.21.41.0
Stereotopy head waving duration, day 70.91.11.50.81.21.2-1.2-0.71.11.11.0-0.91.10.8
Locomotion velocity, session 80.30.30.6-0.7-0.6-0.50.60.8-0.4-0.6-0.30.2-0.6-0.7
Locomotion distance, session 80.81.22.41.51.00.9-0.9-1.01.10.91.1-1.31.01.1
Degree of sensitization distance0.70.71.01.00.70.7-0.7-0.50.90.80.9-1.00.80.7
Degree of sensitization stereotypy3.23.54.61.62.02.1-2.0-1.32.01.91.9-1.91.91.6
Conditioned locomotion0.30.40.50.70.50.6-0.5-0.70.60.50.6-0.70.50.6
Cocaine response after cond. corrected0.10.10.10.40.30.2-0.2-0.10.30.30.3-0.30.30.2
Cocaine response after cond. not corrected0.00.00.00.10.10.1-0.0-0.00.10.20.2-0.20.20.1
Cocaine response before conditioning0.10.10.2-0.4-0.2-0.20.30.3-0.1-0.3-0.1-0.0-0.2-0.3
Saline control response0.81.01.40.91.10.9-1.1-1.21.01.10.9-0.81.11.0
Bone: connectivity density0.00.10.10.40.30.4-0.30.20.30.30.3-0.20.3-0.2
Bone: cortical apparent density2.33.03.71.81.61.7-1.7-1.91.71.71.7-1.71.71.9
Bone: cortical area4.26.37.82.82.52.6-2.4-2.32.52.52.6-2.62.42.4
Bone: cortical porosity0.10.10.20.40.20.2-0.2-0.30.10.20.1-0.00.20.4
Bone: cortical porosity1.01.11.51.21.11.1-1.1-1.11.01.11.0-0.91.11.2
Bone: cortical thickness4.26.97.82.62.62.7-2.5-2.42.72.62.7-2.82.62.6
Bone: cortical thickness0.80.91.21.11.01.1-1.0-0.71.01.01.0-1.00.90.8
Bone: cortical tissue density2.02.63.21.61.51.5-1.5-1.71.61.61.6-1.61.61.8
Condit. Reinf. active minus inactive responses0.20.20.7-0.8-0.3-0.10.20.8-0.3-0.3-0.40.4-0.3-0.5
Condit. Reinf. active-inactive response ratio0.10.10.4-0.60.30.5-0.40.40.30.30.10.10.3-0.1
Condit. Reinf. active responses0.00.00.10.1-0.10.10.10.4-0.0-0.1-0.10.1-0.1-0.1
Condit. Reinf. inactive responses0.20.21.41.20.20.2-0.1-0.60.30.20.3-0.50.20.6
Incentive salience index mean0.20.20.5-0.3-0.4-0.30.40.7-0.5-0.4-0.50.5-0.4-0.6
Condit. Reinf. lever presses0.10.10.60.8-0.2-0.20.20.1-0.3-0.2-0.20.2-0.3-0.1
Condit. Reinf. active minus inactive responses2.12.63.21.61.61.7-1.5-1.31.71.61.7-1.81.61.6
Condit. Reinf. active-inactive response ratio0.10.10.20.30.40.4-0.5-0.00.40.40.4-0.40.40.2
Condit. Reinf. active responses5.06.97.72.72.62.7-2.5-2.42.72.62.7-2.82.62.6
Condit. Reinf. inactive responses4.96.17.92.82.32.5-2.2-2.62.42.42.4-2.52.32.5
Condit. Reinf. lever presses1.11.52.11.01.21.4-1.3-1.11.31.21.2-1.21.11.1
Condit. Reinf. lever reinforcers received5.57.88.72.92.82.9-2.7-2.52.82.82.9-2.92.82.7
Conditioned reinforcement - actives0.60.61.10.5-0.9-1.10.80.0-1.0-0.8-0.90.7-1.00.1
Conditioned reinforcement - inactives0.20.21.11.00.20.1-0.1-0.60.00.20.1-0.20.10.6
Conditioned locomotion0.10.10.60.8-0.1-0.20.1-0.5-0.2-0.1-0.1-0.1-0.20.6
Patch foraging indifference point 0 sec3.45.66.82.62.42.4-2.5-2.22.32.32.4-2.42.22.1
Patch foraging indifference point AUC0.20.31.21.10.20.2-0.1-0.60.40.30.5-0.70.30.5
Delay disc. indifference point, 0s delay0.30.30.4-0.10.50.3-0.6-0.60.60.50.6-0.60.60.6
Delay disc. indifference point, 16s delay4.44.45.1-2.1-2.1-2.22.11.8-2.2-2.1-2.22.3-2.1-1.8
Delay disc. indifference point, 2s delay0.70.71.1-1.1-0.8-0.70.51.0-0.8-0.7-0.91.1-0.7-1.0
Delay disc. indifference point, 24s delay6.46.27.8-2.4-2.5-2.62.42.0-2.6-2.5-2.72.8-2.5-2.2
Delay disc. indifference point, 4s delay0.40.41.2-1.1-0.6-0.70.40.5-0.6-0.5-0.60.7-0.4-0.5
Delay disc. indifference point, 8s delay0.60.61.0-1.0-0.6-0.70.60.7-0.8-0.7-0.91.0-0.7-0.6
Indifference point function ln k0.20.30.70.30.70.7-0.8-0.60.50.70.4-0.20.60.5
Indifference point function log k0.20.30.70.30.70.7-0.8-0.60.50.70.4-0.20.60.5
Patch foraging total patch changes 0 sec3.55.67.42.72.42.4-2.5-2.22.32.32.4-2.42.22.2
Patch foraging total patch changes 12 sec1.21.52.31.51.01.2-1.0-1.31.31.11.3-1.51.11.2
Patch foraging total patch changes 18 sec0.60.81.11.00.80.9-0.8-0.90.90.90.9-0.90.90.8
Patch foraging total patch changes 24 sec0.20.20.40.60.30.3-0.2-0.40.50.30.5-0.70.40.5
Patch foraging total patch changes 6 sec3.24.87.42.72.02.1-2.0-2.12.22.02.3-2.51.92.1
Patch foraging time to switch 0 sec1.42.13.0-1.7-1.4-1.41.41.7-1.3-1.4-1.31.2-1.4-1.7
Patch foraging water rate 0 sec0.00.00.20.4-0.2-0.10.1-0.1-0.1-0.1-0.10.0-0.20.0
Patch foraging water rate 12 sec0.00.10.10.10.30.3-0.2-0.20.30.30.3-0.30.30.3
Patch foraging water rate 18 sec0.00.00.20.4-0.1-0.20.1-0.3-0.1-0.1-0.0-0.0-0.10.4
Patch foraging water rate 24 sec0.10.10.50.70.0-0.10.0-0.70.00.10.1-0.10.10.7
Patch foraging water rate 6 sec0.30.50.8-0.2-0.8-0.70.70.5-0.8-0.8-0.90.9-0.8-0.4
Seeking ratio, delayed vs. immediate footshock1.51.73.0-0.6-1.6-1.61.70.5-1.4-1.5-1.20.8-1.6-0.8
Distance traveled before self-admin2.12.23.0-1.7-1.4-1.41.31.6-1.5-1.4-1.51.6-1.4-1.5
Distance traveled after self-admin0.20.20.7-0.4-0.4-0.50.40.4-0.6-0.4-0.60.8-0.4-0.1
Extensor digitorum longus weight1.35.27.12.32.12.2-2.1-2.22.42.22.5-2.72.22.1
Bone: elastic displacement0.10.10.30.20.30.5-0.3-0.30.40.30.4-0.50.30.4
Bone: elastic work0.10.10.4-0.00.30.6-0.3-0.10.40.30.4-0.40.30.2
Bone: endosteal estimation0.20.30.50.4-0.7-0.60.70.5-0.6-0.7-0.50.3-0.7-0.6
Bone: endosteal perimeter0.00.00.10.20.10.2-0.10.20.10.1-0.00.10.1-0.2
Epididymis fat weight0.10.20.40.2-0.3-0.50.3-0.4-0.6-0.4-0.50.6-0.50.2
Delta time in closed arm before/after self-admin1.11.01.51.11.00.8-0.9-0.91.11.01.1-1.21.00.9
Delta time in open arm before/after self-admin0.00.00.2-0.40.10.0-0.00.3-0.00.0-0.00.10.0-0.3
Diff in mean of infusions in LGA sessions0.70.81.40.70.90.8-0.9-1.20.80.90.7-0.60.91.0
Delay discount exponential model param2.52.63.92.01.51.5-1.4-1.51.61.51.8-1.91.51.4
Extinction: sum of active levers before priming0.00.00.1-0.3-0.1-0.1-0.00.2-0.1-0.1-0.20.2-0.1-0.2
Active lever presses in extinction session 60.20.20.50.10.50.7-0.6-0.20.60.50.5-0.50.50.2
Bone: final force0.20.30.60.80.50.5-0.4-0.50.50.50.5-0.50.50.5
Bone: final moment0.30.61.01.00.70.7-0.7-0.70.70.70.8-0.80.70.7
Food consumed during 24 hour testing period0.00.00.00.1-0.1-0.10.10.0-0.1-0.1-0.10.1-0.1-0.2
Glucose0.10.10.30.2-0.5-0.30.50.3-0.3-0.4-0.20.1-0.4-0.4
Heart weight0.91.22.61.61.00.8-1.0-1.50.91.00.9-0.91.01.3
Delay discount hyperbolic model param2.32.53.81.91.51.5-1.3-1.41.61.51.7-1.91.41.4
Intermittent access intake day 1-15 change0.10.10.40.10.30.2-0.4-0.6-0.10.3-0.20.60.20.5
Intermittent access intake escalation0.50.51.00.40.80.7-0.8-1.00.60.80.4-0.20.70.9
Intermittent access intake escalation 20.70.71.20.41.10.8-1.1-1.10.61.00.40.01.01.0
Intermitt. access day 1 inactive lever presses0.80.81.2-0.8-0.9-0.91.00.8-0.9-0.9-0.90.8-0.9-1.1
Intermitt. access day 15 inactive lever presses0.80.91.9-0.9-0.9-0.80.81.3-0.8-0.9-0.80.7-0.8-1.4
Intermitt. access escalation Index1.31.11.50.91.21.1-1.2-0.91.11.21.1-0.91.20.9
Intermittent access day 1 total infusions0.20.20.40.4-0.5-0.60.60.3-0.6-0.5-0.40.3-0.6-0.3
Intermittent access day 15 total infusions0.10.10.20.4-0.1-0.30.2-0.3-0.4-0.2-0.30.4-0.30.2
Intermittent access terminal intake (last 3 days)0.10.10.50.1-0.2-0.40.20.0-0.5-0.3-0.60.7-0.4-0.1
Intermittent access total infusions0.10.10.20.2-0.2-0.40.20.0-0.4-0.2-0.40.4-0.4-0.0
Intermittent access day 1 locomotion1.01.03.51.90.80.7-0.8-1.10.70.80.9-1.00.71.1
Intermittent access day 15 total locomotion0.40.50.70.80.80.7-0.8-0.60.60.70.6-0.50.60.7
Intermittent access total locomotion0.10.10.60.80.2-0.0-0.2-0.4-0.10.10.0-0.1-0.00.4
Intermittent access standard deviation0.10.20.6-0.5-0.1-0.30.10.2-0.5-0.2-0.50.8-0.3-0.2
Left kidney weight0.41.01.91.41.00.8-0.9-0.90.90.91.0-1.20.80.9
Right kidney weight0.30.81.11.01.00.9-0.8-1.00.80.90.9-0.90.80.9
Cocaine induced anxiety0.20.20.30.40.50.4-0.5-0.40.50.50.4-0.30.50.3
Post-drug Anxiety0.00.00.0-0.1-0.1-0.10.00.1-0.1-0.1-0.10.2-0.1-0.1
Baseline Anxiety2.32.53.5-1.8-1.6-1.51.61.9-1.5-1.6-1.41.2-1.6-1.7
Tail length1.13.46.82.11.71.6-1.6-2.61.61.71.6-1.51.72.3
Length with tail3.211.816.53.83.43.3-3.3-4.13.23.33.2-3.13.23.8
Length without tail4.29.110.83.33.03.0-3.0-3.03.03.03.0-3.02.92.9
Times rat made contact with spout0.70.81.3-1.1-0.8-0.80.80.8-0.9-0.8-1.01.2-0.9-0.9
Lifetime Intake0.30.30.5-0.1-0.6-0.70.60.3-0.7-0.6-0.60.6-0.7-0.2
Liver weight, left1.32.12.71.11.61.5-1.6-1.61.31.51.3-1.01.51.6
Liver weight, right0.20.31.10.60.50.3-0.4-1.10.30.40.3-0.30.30.7
Locomotor activity7.712.213.73.53.63.4-3.7-3.53.43.63.4-3.23.63.5
Locomotor testing distance15.225.429.14.85.25.0-5.4-4.95.05.24.9-4.75.25.0
Locomotor testing rearing13.220.422.74.54.64.3-4.7-4.64.44.64.4-4.24.74.8
Locomotion in novel chamber0.30.30.60.50.60.7-0.5-0.30.70.50.7-0.80.50.4
Locomotion in novel chamber post-restriction0.10.10.2-0.3-0.5-0.20.40.3-0.4-0.4-0.50.5-0.5-0.2
Fecal boli incidents, locomotor time 11.11.21.70.81.21.3-1.2-1.11.11.21.0-0.91.11.0
Change in fecal boli incidents, locomotor task2.62.53.0-1.4-1.5-1.51.61.7-1.5-1.6-1.51.4-1.6-1.7
Time >=10cm from walls, locomotor time 10.80.81.3-0.6-0.9-0.81.20.4-1.0-1.0-1.11.0-1.0-0.6
Bouts of movement, locomotor time 11.61.83.0-1.2-1.2-1.71.40.6-1.5-1.3-1.61.7-1.3-0.7
Total resting periods, locomotor time 12.62.94.3-1.4-1.6-2.01.81.0-1.9-1.7-1.92.1-1.7-1.1
Rest time, locomotor task time 10.30.40.8-0.3-0.7-0.90.70.2-0.7-0.7-0.60.6-0.6-0.3
Distance moved, locomotor task time 11.71.82.71.11.51.6-1.5-1.11.41.51.3-1.21.41.1
Vertical activity count, locomotor time 10.80.81.40.51.01.2-1.0-0.51.01.01.0-0.90.90.6
Time >=10cm from walls, locomotor time 20.40.40.60.50.60.7-0.5-0.80.60.60.6-0.60.60.7
Bouts of movement, locomotor time 20.10.10.30.10.40.2-0.4-0.60.30.40.3-0.20.40.4
Total resting periods, locomotor time 20.00.00.1-0.20.1-0.1-0.2-0.20.00.1-0.00.20.20.1
Rest time, locomotor task time 23.74.25.1-1.8-2.1-2.01.82.3-2.1-2.0-2.12.1-2.0-2.2
Distance moved, locomotor task time 21.72.02.31.11.51.4-1.3-1.51.51.41.4-1.41.41.4
Vertical activity count, locomotor time 21.01.11.70.51.21.3-1.1-0.91.21.11.1-1.11.10.7
Light reinforcement 10.30.60.80.70.90.9-0.9-0.40.80.80.7-0.70.80.9
Light reinforcement 20.70.91.50.81.10.9-1.0-1.10.91.00.8-0.71.01.2
Bone: marrow area0.20.50.70.2-0.8-0.70.80.6-0.7-0.8-0.60.4-0.8-0.7
Bone: maximum diameter0.20.41.31.10.50.6-0.5-0.70.60.50.6-0.70.50.6
Bone: maximum force0.30.61.31.10.70.7-0.6-0.70.70.70.8-0.90.60.7
Bone: maximum moment0.61.11.91.41.01.1-0.9-1.01.00.91.0-1.20.90.9
Mean time between licks in bursts0.20.30.4-0.4-0.6-0.50.60.6-0.5-0.6-0.50.4-0.6-0.6
Mean num. licks in bursts1.11.32.1-1.5-1.0-1.11.00.9-1.2-1.0-1.21.3-1.0-1.1
Cd content in liver11.512.614.73.73.43.4-3.4-3.73.53.53.6-3.73.53.8
Co content in liver2.63.04.02.01.61.7-1.6-1.71.71.71.8-1.91.71.8
Cu content in liver0.00.00.1-0.30.10.2-0.1-0.3-0.10.1-0.20.30.00.1
Fe content in liver0.30.40.60.40.60.8-0.6-0.40.70.60.7-0.70.60.4
K content in liver0.60.51.1-1.0-0.5-0.60.50.7-0.8-0.6-0.91.1-0.6-0.7
Mg content in liver2.52.64.0-1.6-1.5-1.61.41.4-1.7-1.5-1.82.0-1.5-1.5
Mn content in liver0.00.00.1-0.1-0.2-0.20.1-0.1-0.3-0.1-0.30.4-0.2-0.1
Na content in liver4.75.05.6-2.0-2.2-2.22.32.1-2.3-2.3-2.32.2-2.4-2.3
Rb content in liver1.01.21.51.11.11.2-1.1-1.11.11.11.1-1.01.01.1
Se content in liver1.11.32.4-1.1-1.0-1.21.00.6-1.3-1.1-1.41.5-1.1-0.8
Sr content in liver0.50.51.51.20.40.4-0.4-0.80.50.50.6-0.80.51.0
Zn content in liver0.60.61.1-0.9-0.7-0.90.60.6-0.8-0.7-0.91.1-0.7-0.7
Bone: minimum diameter0.00.00.20.40.00.20.0-0.10.10.00.2-0.30.00.0
Time in familiar zone, hab. session 10.30.30.50.70.50.6-0.5-0.20.60.50.5-0.60.50.4
Time in novel zone, hab. session 12.92.93.1-1.7-1.6-1.71.71.6-1.7-1.7-1.71.8-1.7-1.7
Total zone transitions, hab. session 10.50.71.1-0.7-1.0-0.81.01.1-0.7-1.0-0.70.4-0.9-1.0
Total locomotion distance, hab. session 10.10.20.80.60.20.5-0.2-0.00.50.20.6-0.90.20.2
Locomotion velocity, hab. session 10.30.41.40.80.40.7-0.4-0.40.80.50.9-1.20.50.6
Time in familiar zone, hab. session 21.81.92.31.01.51.4-1.5-1.51.41.51.3-1.21.51.4
Time in novel zone, hab. session 21.11.11.5-0.7-1.2-1.11.21.2-1.1-1.1-1.00.8-1.1-1.1
Total zone transitions, hab. session 20.70.91.3-0.9-1.1-0.91.10.8-0.9-1.0-0.80.7-1.0-0.9
Total locomotion distance, hab. session 20.10.10.3-0.2-0.5-0.40.50.3-0.3-0.5-0.20.0-0.5-0.4
Locomotion velocity, hab. session 20.20.30.6-0.3-0.8-0.60.80.5-0.5-0.7-0.40.2-0.7-0.6
Novel to familiar place preference ratio2.72.83.8-0.9-1.9-2.01.91.5-1.8-1.8-1.71.5-1.8-1.5
Novelty place preference2.02.03.0-0.6-1.6-1.71.61.2-1.5-1.5-1.41.3-1.5-1.2
Time in novel zone, NPP test2.32.43.4-0.7-1.8-1.91.71.4-1.7-1.7-1.51.4-1.6-1.3
Total zone transitions, NPP test0.00.10.2-0.3-0.3-0.10.30.4-0.1-0.3-0.1-0.1-0.2-0.4
Total locomotion distance, NPP test0.40.51.00.60.60.9-0.6-0.30.90.70.9-1.00.70.5
Locomotion velocity, NPP test0.50.71.20.80.71.0-0.7-0.41.00.71.0-1.10.80.6
Intraocular pressure0.10.20.4-0.20.50.5-0.5-0.00.60.60.5-0.30.60.3
Delta distance traveled before/after self-admin0.30.40.70.80.60.6-0.6-0.80.50.60.4-0.20.60.8
Delta ambulatory time before/after self-admin0.50.61.10.70.70.7-0.7-1.10.70.70.6-0.40.71.0
Parametrial fat weight0.00.10.20.10.20.2-0.1-0.40.20.20.3-0.40.10.5
Pavlov. Cond. lever latency0.00.10.4-0.70.20.0-0.20.10.10.10.10.00.1-0.1
Pavlov. Cond. magazine entry latency0.10.10.20.1-0.4-0.40.40.2-0.4-0.3-0.40.4-0.4-0.3
Pavlov. Cond. change in total contacts0.80.81.91.40.70.8-0.8-1.30.70.80.7-0.70.81.1
Pavlov. Cond. index score0.10.10.20.3-0.4-0.30.4-0.0-0.4-0.3-0.30.3-0.4-0.2
Pavlov. Cond. latency score0.10.10.20.3-0.4-0.30.3-0.1-0.4-0.3-0.30.3-0.4-0.1
Pavlov. Cond. lever contacts0.50.51.71.30.50.7-0.6-0.80.60.60.6-0.70.60.7
Pavlov. Cond. magazine entry number0.00.00.1-0.30.1-0.10.00.1-0.0-0.0-0.00.10.00.0
Pavlov. Cond. intertrial magazine entries2.22.63.41.61.61.7-1.6-1.21.81.61.8-1.81.71.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.6-0.3-0.20.2-0.3-0.2-0.2-0.10.1-0.20.1
Pavlov. Cond. response bias0.00.10.50.7-0.10.00.1-0.3-0.0-0.00.1-0.2-0.10.1
Pavlov. Cond. lever latency0.30.40.8-0.5-0.5-0.90.60.6-0.6-0.6-0.60.7-0.5-0.5
Pavlov. Cond. magazine entry latency0.10.10.1-0.3-0.30.10.30.3-0.2-0.3-0.20.1-0.4-0.4
Pavlov. Cond. change in total contacts0.70.91.51.00.91.2-0.9-1.20.90.90.9-0.90.81.0
Pavlov. Cond. index score0.30.41.00.40.61.0-0.6-0.70.60.60.6-0.60.50.5
Pavlov. Cond. latency score0.40.51.10.50.71.1-0.7-0.70.70.70.7-0.70.60.6
Pavlov. Cond. lever contacts0.10.10.30.20.20.6-0.2-0.30.30.20.2-0.30.10.1
Pavlov. Cond. magazine entry number0.91.21.9-0.9-1.1-1.41.11.1-1.1-1.1-1.01.0-1.0-1.1
Pavlov. Cond. intertrial magazine entries0.81.11.50.91.11.1-1.1-0.21.21.11.2-1.21.10.7
Pavlov. Cond. lever-magazine prob. diff.0.20.30.70.30.50.8-0.5-0.70.50.50.4-0.40.40.5
Pavlov. Cond. response bias0.10.10.30.10.20.6-0.2-0.30.20.20.2-0.30.10.2
Time in closed arm before self-admin0.50.50.7-0.8-0.7-0.50.60.5-0.8-0.7-0.80.9-0.8-0.7
Time in closed arm after self-admin0.50.50.90.70.60.7-0.7-0.50.80.60.8-0.90.60.5
Time in open arm before self-admin0.30.30.40.20.60.6-0.6-0.40.60.60.6-0.50.60.5
Time in open arm after self-admin0.91.01.20.81.11.0-1.1-0.81.01.11.0-1.01.10.8
Bone: periosteal estimation0.61.23.21.80.91.1-0.9-1.11.00.91.1-1.20.91.0
Bone: periosteal perimeter1.01.62.31.31.41.5-1.4-0.91.31.31.3-1.21.31.0
Bone: post-yield work1.62.23.81.91.41.4-1.4-1.61.41.41.4-1.51.41.5
Progressive ratio test 1 active lever presses0.10.10.30.60.30.3-0.2-0.40.30.30.3-0.40.20.4
Progressive ratio test 1 breakpoint0.00.00.20.40.10.2-0.0-0.30.10.10.2-0.30.10.3
Progressive ratio test 1 inactive lever presses1.92.12.3-1.2-1.4-1.51.51.4-1.5-1.4-1.51.5-1.5-1.5
Progressive ratio test 2 active lever presses0.30.40.50.70.60.5-0.6-0.70.50.60.5-0.50.50.7
Progressive ratio test 2 breakpoint0.10.20.40.60.40.2-0.3-0.60.20.40.3-0.20.30.5
Progressive ratio test 2 inactive lever presses0.00.00.10.30.1-0.1-0.0-0.1-0.10.1-0.00.10.10.0
Incentive Sensitization - Responses1.01.01.21.01.11.1-1.1-1.01.01.11.0-0.81.00.9
Incentive Sensitization - Breakpoint1.31.31.61.01.21.2-1.2-1.11.11.21.1-0.91.21.1
Sum of active levers in priming session hrs 5-60.10.10.20.00.50.4-0.5-0.10.50.40.4-0.40.40.2
Progressive ratio0.10.10.30.5-0.2-0.20.4-0.1-0.2-0.2-0.10.0-0.30.1
Food seeking constrained by brief footshock0.10.20.30.20.40.5-0.3-0.40.50.40.4-0.50.40.5
Seeking ratio, punishment vs. effort0.30.30.5-0.10.70.7-0.7-0.50.60.70.5-0.40.70.5
Retroperitoneal fat weight0.82.54.2-0.8-2.0-1.82.01.0-1.7-1.9-1.51.1-1.9-1.1
Reaction time number correct11.116.017.44.04.13.9-4.0-4.24.04.04.0-3.84.14.0
Reaction time mean minus median6.48.510.2-2.7-2.9-2.63.03.2-2.8-2.9-2.92.8-2.9-3.2
Reaction time mean minus median AUC4.15.36.5-2.2-2.3-2.12.42.5-2.2-2.3-2.32.2-2.3-2.5
Reaction time num false alarms2.93.96.12.51.92.0-2.0-1.71.91.92.0-2.11.81.9
Reaction time num false alarms AUC2.23.05.32.31.61.7-1.7-1.41.61.61.7-1.91.51.7
Reaction time trials correct on left11.116.017.44.04.13.9-4.0-4.24.04.04.0-3.84.14.0
Reaction time trials on left11.316.217.54.04.13.9-4.0-4.24.04.14.0-3.94.14.0
Reaction time mean8.111.412.4-3.2-3.5-3.43.53.5-3.3-3.4-3.33.1-3.4-3.4
Reaction time mean AUC8.110.911.8-3.3-3.4-3.33.43.4-3.3-3.3-3.23.1-3.3-3.3
Median of all reaction times6.28.59.6-2.8-3.1-3.13.12.9-2.9-3.0-2.82.7-3.0-2.8
Reaction time omissions0.10.10.4-0.0-0.2-0.20.30.4-0.3-0.2-0.30.3-0.3-0.6
Reaction time false alarm rate0.30.51.0-0.1-0.8-0.50.61.0-0.7-0.7-0.60.4-0.8-0.7
Reaction time premature initiation rate0.30.40.60.80.50.6-0.7-0.40.60.50.6-0.70.50.5
Reaction time premature initiations4.76.67.42.72.62.5-2.7-2.52.62.52.6-2.62.52.5
Std. dev. reaction times4.96.98.7-2.6-2.6-2.42.72.9-2.5-2.6-2.52.5-2.6-2.9
Reaction time trials completed11.316.217.54.04.13.9-4.0-4.24.04.14.0-3.94.14.0
Reaction time trials AUC12.017.218.44.24.34.0-4.2-4.34.14.24.1-4.04.24.1
Run reversals in cocaine runway, females1.71.72.20.91.31.1-1.2-1.31.31.21.4-1.51.31.5
Run reversals in cocaine runway, males0.00.00.1-0.1-0.3-0.20.3-0.0-0.1-0.3-0.0-0.2-0.20.0
Latency to leave start box in cocaine runway1.31.41.9-1.3-1.2-1.21.01.3-1.2-1.1-1.21.4-1.0-1.2
Latency to leave start box in cocaine runway, F0.91.01.6-1.3-0.9-0.90.81.3-1.0-0.8-1.01.3-0.8-1.0
Latency to leave start box in cocaine runway, M0.60.61.0-1.0-0.8-0.80.70.8-0.7-0.7-0.70.7-0.7-1.0
Std. dev. time between licks in bursts0.10.10.20.3-0.4-0.20.4-0.2-0.2-0.3-0.1-0.1-0.30.1
Total sessions with >9 infusions0.00.00.10.0-0.2-0.10.3-0.0-0.1-0.2-0.0-0.2-0.30.2
Short access day 1 total inactive lever presses0.10.10.40.40.40.3-0.3-0.70.30.30.3-0.30.30.4
Short access day 10 total inactive lever presses0.00.00.1-0.30.20.1-0.1-0.00.20.10.2-0.10.2-0.2
Short access day 1 total infusions0.10.10.30.50.1-0.10.1-0.60.10.00.3-0.50.00.6
Short access day 10 total infusions0.10.10.20.2-0.4-0.40.30.2-0.4-0.4-0.40.3-0.4-0.0
Short access total infusions0.70.81.5-0.3-1.1-1.21.10.6-1.0-1.1-0.90.7-1.1-0.5
Short access day 1 locomotion0.10.10.20.3-0.4-0.50.40.3-0.4-0.4-0.30.2-0.4-0.2
Short access day 10 total locomotion0.30.40.70.8-0.7-0.70.70.1-0.6-0.7-0.40.0-0.8-0.0
Short access total locomotion0.30.30.60.8-0.7-0.70.80.1-0.5-0.7-0.2-0.2-0.70.0
One hour access (0.3 mA shock)0.20.20.70.60.50.3-0.6-0.60.20.50.2-0.10.40.8
Compulsive drug intake1.91.92.50.81.41.5-1.6-1.11.41.51.4-1.21.51.4
One hour access (shock baseline)0.00.10.10.1-0.1-0.30.1-0.2-0.3-0.1-0.30.4-0.20.2
Social response proportion0.10.10.20.20.20.3-0.1-0.40.30.20.3-0.40.20.3
Social responses0.10.10.40.6-0.00.00.1-0.40.10.00.1-0.20.10.4
Social time1.01.31.9-1.3-1.0-1.11.01.4-1.1-1.0-1.21.3-1.0-1.3
Soleus weight0.20.50.60.60.70.8-0.7-0.60.80.70.7-0.60.80.5
Bone: stiffness0.20.31.01.00.50.3-0.4-0.70.40.40.4-0.40.40.5
Tibialis anterior weight0.51.62.31.51.11.0-1.0-1.41.31.11.3-1.51.21.3
Time to tail flick, vehicle, before self-admin1.61.62.3-1.5-1.3-1.21.21.3-1.2-1.3-1.21.1-1.3-1.3
Time to tail flick, vehicle, after self-admin0.10.10.10.20.30.1-0.2-0.40.20.30.2-0.10.30.3
Time to tail flick, test, before self-admin0.30.30.7-0.4-0.5-0.20.50.8-0.4-0.5-0.50.4-0.5-0.7
Time to tail flick, test, after self-admin0.50.50.8-0.5-0.9-0.80.90.8-0.6-0.8-0.50.3-0.7-0.6
Delta time to tail flick, vehicle, before/after SA3.53.43.91.91.91.8-1.9-1.81.82.01.8-1.72.01.8
Delta time to tail flick, test, before/after SA0.30.30.6-0.4-0.7-0.80.70.4-0.5-0.6-0.50.4-0.5-0.3
Tibia length0.10.30.40.50.50.6-0.6-0.60.50.50.5-0.40.50.6
Ambulatory time before self-admin4.54.75.7-2.4-2.0-2.02.02.4-2.1-2.0-2.22.3-2.0-2.4
Ambulatory time after self-admin1.41.52.2-1.2-1.2-1.21.21.1-1.3-1.2-1.41.5-1.2-1.0
Bone: tissue strength0.10.10.1-0.3-0.4-0.30.40.1-0.4-0.4-0.40.4-0.4-0.2
Total heroin consumption0.00.00.1-0.3-0.10.00.10.2-0.0-0.1-0.0-0.0-0.10.0
Bone: trabecular number0.30.50.80.90.70.9-0.7-0.40.70.70.7-0.70.70.4
Bone: trabecular spacing0.00.00.1-0.3-0.0-0.20.0-0.1-0.0-0.00.0-0.0-0.00.2
Bone: trabecular thickness3.34.05.92.41.92.0-1.8-1.92.01.92.1-2.21.91.9
Bone: trabecular tissue density0.00.10.1-0.2-0.3-0.30.30.2-0.2-0.3-0.20.0-0.30.0
Water consumed over 24 hours0.00.00.10.10.10.1-0.1-0.30.00.1-0.00.10.10.1
Number of responses in last shaping day1.01.01.7-1.3-0.8-0.90.90.9-1.0-0.9-1.01.1-0.9-1.0