Hub : Genes

Fnbp4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039104893.1 0.02 0.01 2.6e-03 0.01 0.01 0.03 0.01 1.3e-02 8.7e-03 8.2e-04 2.4e-02
2 IL mRNA stability Fnbp4 0.26 0.17 6.8e-03 0.02 0.05 0.05 0.05 1.2e-01 2.8e-02 2.2e-02 2.3e-02
3 Adipose intron excision ratio chr3_76750091_76750414 0.02 0.02 9.9e-03 0.02 0.01 0.01 0.01 4.3e-03 1.3e-02 2.5e-02 1.1e-02
4 Adipose mRNA stability Fnbp4 0.03 0.02 1.1e-03 0.02 0.03 0.02 0.02 1.3e-03 8.4e-04 4.4e-03 1.4e-03
5 Brain isoform ratio XM_039104893.1 0.02 0.01 9.4e-03 0.03 0.02 0.03 0.03 8.2e-04 9.6e-03 1.8e-03 1.3e-03
6 Brain gene expression Fnbp4 0.04 0.03 7.7e-04 0.02 0.03 0.03 0.03 2.3e-03 6.0e-04 1.8e-03 1.3e-03
7 Adipose gene expression Fnbp4 0.06 0.03 1.8e-10 0.08 0.08 0.08 0.08 1.7e-09 1.3e-09 1.7e-09 1.2e-09
8 PL gene expression Fnbp4 0.04 0.03 3.9e-03 0.01 0.02 0.02 0.02 2.2e-02 1.4e-03 6.1e-03 4.5e-03
9 Adipose intron excision ratio chr3_76750516_76751077 0.03 0.03 1.8e-03 0.02 0.01 0.01 0.01 3.3e-03 8.2e-03 3.1e-02 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.22.03.10.9-0.7-1.61.5-1.81.61.51.61.2
Area under the delay curve1.11.14.80.72.20.9-1.10.4-1.0-0.9-0.8-0.6
BMI with tail0.82.74.5-2.00.0-1.82.1-2.01.81.51.31.0
BMI without tail2.44.96.8-2.61.4-2.02.1-2.42.32.32.12.3
Body weight0.31.13.4-1.8-1.5-0.71.3-0.51.00.70.20.5
Weight adjusted by age1.31.54.2-1.90.12.0-1.21.3-1.0-0.8-0.8-0.5
Bone surface2.13.86.70.9-1.4-2.62.5-2.42.21.71.81.2
Bone volume2.23.75.91.1-1.5-2.42.3-2.32.21.81.91.3
Breakpoint value in progressive ratio session0.91.02.20.80.20.8-0.90.9-1.1-1.3-1.2-1.5
Number of licking bursts1.01.21.8-1.31.21.4-1.21.3-1.0-0.8-0.8-0.2
Context. condit. distance diff. score0.10.10.40.40.10.5-0.60.6-0.3-0.10.30.1
Locomotion velocity, session 10.00.00.3-0.1-0.2-0.10.00.1-0.1-0.1-0.2-0.5
Locomotion distance, session 10.60.73.2-1.8-0.2-0.40.8-0.50.70.80.31.0
Locomotion velocity, session 20.81.05.1-2.31.7-0.30.4-0.50.1-0.2-0.4-0.3
Locomotion distance, session 20.50.75.1-2.30.0-0.10.5-0.40.40.4-0.30.5
Locomotion velocity, session 31.21.42.60.21.31.0-1.01.0-1.3-1.3-1.5-1.6
Locomotion distance, session 30.70.81.6-0.20.91.3-1.20.9-1.0-0.7-0.9-0.4
Stereotopy head waving bouts, day 31.21.42.5-1.51.2-1.41.4-1.61.10.90.80.1
Stereotopy head waving duration, day 31.21.43.9-2.01.2-1.31.3-1.41.00.80.70.2
Locomotion velocity, session 70.20.30.9-0.70.00.6-0.50.9-0.3-0.2-0.20.3
Locomotion distance, session 71.21.55.6-2.40.21.5-1.11.7-0.7-0.5-0.60.7
Stereotopy head waving bouts, day 72.52.85.11.6-0.9-2.21.9-1.81.71.71.90.6
Stereotopy head waving duration, day 72.73.25.21.6-0.5-2.32.0-2.11.92.02.01.0
Locomotion velocity, session 80.10.20.7-0.60.30.20.0-0.20.20.40.20.8
Locomotion distance, session 80.30.52.3-1.50.10.7-0.50.6-0.10.20.20.9
Degree of sensitization distance1.21.24.6-2.1-0.3-0.60.9-0.41.00.90.91.5
Degree of sensitization stereotypy1.71.99.13.0-1.8-1.20.8-0.70.70.80.9-0.1
Conditioned locomotion0.20.31.0-1.00.00.5-0.40.5-0.4-0.3-0.5-0.4
Cocaine response after cond. corrected1.21.42.30.40.01.4-1.51.5-1.4-1.1-1.2-1.2
Cocaine response after cond. not corrected0.30.40.9-0.2-0.60.7-0.61.0-0.6-0.3-0.7-0.6
Cocaine response before conditioning2.32.83.8-1.4-0.9-1.71.9-1.61.91.91.61.7
Saline control response0.30.41.7-1.30.9-0.10.1-0.50.30.50.60.6
Bone: connectivity density1.11.72.70.8-0.2-1.51.3-1.71.41.31.71.2
Bone: cortical apparent density0.30.30.80.20.70.5-0.50.3-0.6-0.5-0.7-0.9
Bone: cortical area1.62.46.2-0.6-2.5-1.81.9-1.11.71.41.21.1
Bone: cortical porosity0.10.10.20.20.4-0.30.3-0.20.1-0.2-0.3-0.5
Bone: cortical porosity0.10.10.2-0.30.4-0.40.5-0.30.20.1-0.1-0.3
Bone: cortical thickness0.20.32.0-0.5-1.40.10.00.30.10.10.10.2
Bone: cortical thickness0.40.52.20.8-1.50.3-0.10.5-0.3-0.5-0.7-0.3
Bone: cortical tissue density0.40.51.20.40.80.6-0.70.3-0.8-0.7-0.8-1.1
Condit. Reinf. active minus inactive responses0.30.30.6-0.40.80.6-0.50.1-0.6-0.6-0.7-0.6
Condit. Reinf. active-inactive response ratio0.20.20.60.80.20.1-0.2-0.2-0.3-0.3-0.4-0.7
Condit. Reinf. active responses0.50.72.1-1.40.91.0-0.80.6-0.6-0.5-0.6-0.0
Condit. Reinf. inactive responses0.70.85.1-2.30.60.6-0.40.40.00.20.31.0
Incentive salience index mean0.30.31.0-1.00.50.5-0.40.3-0.5-0.5-0.7-0.5
Condit. Reinf. lever presses0.50.74.7-2.20.20.7-0.40.7-0.4-0.3-0.6-0.1
Condit. Reinf. active minus inactive responses0.50.71.60.40.1-0.90.7-0.90.90.81.30.8
Condit. Reinf. active-inactive response ratio0.10.10.80.50.9-0.1-0.0-0.30.0-0.10.1-0.0
Condit. Reinf. active responses0.91.32.2-0.1-1.0-1.31.2-0.81.31.21.51.1
Condit. Reinf. inactive responses1.72.15.9-0.9-2.4-1.41.4-0.41.51.51.51.3
Condit. Reinf. lever presses1.41.82.7-1.3-0.9-1.51.6-1.11.61.51.31.2
Condit. Reinf. lever reinforcers received0.81.22.0-0.0-1.2-1.31.1-0.71.21.11.40.9
Conditioned reinforcement - actives1.61.66.82.6-2.4-0.2-0.40.8-0.4-0.40.1-0.6
Conditioned reinforcement - inactives0.60.74.11.2-2.0-0.80.40.00.20.10.2-0.4
Conditioned locomotion0.30.41.31.1-0.50.0-0.20.1-0.4-0.7-0.0-1.1
Patch foraging indifference point 0 sec0.40.62.1-0.5-1.50.4-0.21.00.20.50.70.9
Patch foraging indifference point AUC1.01.27.7-2.80.41.0-0.30.4-0.5-0.5-1.00.1
Delay disc. indifference point, 0s delay0.40.40.9-0.10.90.8-0.80.7-0.7-0.4-0.50.0
Delay disc. indifference point, 16s delay0.50.63.90.02.0-0.00.0-0.6-0.2-0.4-0.5-0.6
Delay disc. indifference point, 2s delay0.20.20.8-0.40.30.5-0.50.9-0.4-0.2-0.50.3
Delay disc. indifference point, 24s delay0.10.10.4-0.70.30.30.1-0.30.20.20.30.3
Delay disc. indifference point, 4s delay0.90.94.30.62.10.7-1.00.5-0.8-0.5-0.80.0
Delay disc. indifference point, 8s delay0.90.94.80.42.20.9-0.9-0.1-0.8-0.8-0.5-0.8
Indifference point function ln k0.71.02.81.7-0.90.4-0.61.0-0.8-1.0-0.6-1.3
Indifference point function log k0.71.02.81.7-0.90.4-0.61.0-0.8-1.0-0.6-1.3
Patch foraging total patch changes 0 sec0.30.51.9-0.5-1.40.4-0.20.90.20.40.70.9
Patch foraging total patch changes 12 sec1.01.35.1-2.3-0.8-0.20.9-0.51.01.00.81.4
Patch foraging total patch changes 18 sec0.60.83.3-1.80.41.1-0.91.0-0.4-0.00.10.5
Patch foraging total patch changes 24 sec1.51.911.2-3.3-0.41.4-0.30.50.20.70.21.6
Patch foraging total patch changes 6 sec1.11.79.6-3.1-0.50.70.00.60.50.90.51.8
Patch foraging time to switch 0 sec0.40.75.12.3-0.50.1-0.60.3-0.20.20.6-0.1
Patch foraging water rate 0 sec0.61.05.8-2.4-0.7-0.81.2-0.50.80.30.00.1
Patch foraging water rate 12 sec0.30.51.7-1.30.30.30.2-0.2-0.2-0.8-1.0-0.8
Patch foraging water rate 18 sec1.21.63.81.0-0.80.7-0.71.0-1.2-1.6-1.9-1.9
Patch foraging water rate 24 sec0.60.82.4-1.4-0.40.9-0.20.7-0.6-0.9-1.5-0.7
Patch foraging water rate 6 sec0.30.40.9-0.1-1.0-0.90.9-0.40.40.1-0.4-0.5
Seeking ratio, delayed vs. immediate footshock0.30.42.3-1.5-0.80.30.20.20.20.2-0.00.5
Distance traveled before self-admin0.60.75.5-0.22.30.4-0.4-0.3-0.1-0.00.00.2
Distance traveled after self-admin0.70.82.1-1.41.40.9-0.70.7-0.20.1-0.11.2
Extensor digitorum longus weight0.10.51.1-0.6-0.3-1.01.1-0.70.90.60.50.7
Bone: elastic displacement1.41.62.6-1.10.81.4-1.21.2-1.4-1.4-1.6-1.1
Bone: elastic work0.20.21.2-1.1-0.60.10.20.20.0-0.1-0.5-0.2
Bone: endosteal estimation2.45.312.0-0.8-2.1-3.23.5-2.42.72.01.41.1
Bone: endosteal perimeter1.02.14.10.2-2.0-1.82.0-1.21.61.30.90.8
Epididymis fat weight0.81.910.3-3.21.51.3-0.60.6-0.6-0.8-0.9-0.3
Delta time in closed arm before/after self-admin1.51.42.3-1.40.9-1.11.3-1.51.31.10.91.2
Delta time in open arm before/after self-admin1.71.62.60.4-1.01.2-1.21.6-1.4-1.3-1.5-1.4
Diff in mean of infusions in LGA sessions1.51.73.5-1.9-0.51.5-1.01.7-1.1-0.8-1.7-0.7
Delay discount exponential model param1.01.03.8-0.4-1.9-1.11.2-0.51.00.80.80.4
Extinction: sum of active levers before priming0.20.20.5-0.1-0.40.3-0.20.3-0.4-0.5-0.7-0.4
Active lever presses in extinction session 61.00.93.5-0.9-1.90.9-0.71.5-0.6-0.3-0.5-0.0
Bone: final force2.44.06.1-2.1-1.2-2.22.5-1.62.32.21.71.8
Bone: final moment2.94.77.1-2.3-1.3-2.42.7-1.82.52.41.92.0
Food consumed during 24 hour testing period0.50.72.9-1.7-0.5-0.50.7-0.50.70.70.40.7
Glucose0.71.16.32.5-0.8-0.2-0.60.8-0.7-0.2-0.8-0.8
Heart weight0.30.41.0-0.40.91.0-0.2-0.50.10.30.10.9
Delay discount hyperbolic model param1.01.13.2-0.4-1.8-1.11.3-0.71.10.91.00.4
Intermittent access intake day 1-15 change2.01.913.43.70.7-1.50.3-0.90.20.00.5-0.5
Intermittent access intake escalation1.61.58.93.00.6-1.40.4-1.10.50.50.90.1
Intermittent access intake escalation 22.42.319.44.40.1-0.8-0.6-0.0-0.4-0.40.2-0.6
Intermitt. access day 1 inactive lever presses0.60.73.60.2-1.90.3-0.20.8-0.4-0.5-0.4-1.0
Intermitt. access day 15 inactive lever presses5.15.514.83.8-3.80.6-1.83.1-1.6-1.4-1.5-1.0
Intermitt. access escalation Index0.40.42.20.21.50.5-0.6-0.1-0.20.20.30.5
Intermittent access day 1 total infusions0.60.72.2-1.4-1.5-0.20.6-0.10.60.60.40.6
Intermittent access day 15 total infusions1.31.53.51.9-0.4-1.70.9-1.11.01.11.20.9
Intermittent access terminal intake (last 3 days)1.21.37.82.8-0.8-1.20.3-0.60.50.50.90.5
Intermittent access total infusions1.41.62.80.8-0.8-1.71.3-1.41.31.31.41.1
Intermittent access day 1 locomotion1.21.22.4-1.5-0.5-0.50.9-0.61.11.31.21.5
Intermittent access day 15 total locomotion1.41.52.40.80.2-1.51.2-1.51.31.31.61.0
Intermittent access total locomotion1.82.13.5-0.10.1-1.51.5-1.81.61.71.91.5
Intermittent access standard deviation2.12.215.53.90.4-1.60.4-0.80.40.30.8-0.1
Left kidney weight0.20.62.3-1.5-0.7-0.00.7-0.40.70.70.21.2
Right kidney weight0.20.73.9-0.8-2.00.10.40.60.20.0-0.60.6
Cocaine induced anxiety2.22.511.4-1.5-3.4-0.51.10.21.21.41.41.5
Post-drug Anxiety0.40.51.30.5-1.2-0.40.20.30.50.80.71.1
Baseline Anxiety3.23.413.70.23.71.6-1.70.6-1.7-1.7-1.9-1.3
Tail length0.10.41.5-0.2-0.2-0.60.3-0.10.61.00.81.2
Length with tail0.31.37.01.4-2.70.1-0.31.4-0.3-0.3-0.5-0.0
Length without tail1.63.58.83.0-2.70.7-0.91.8-1.3-1.8-1.7-1.7
Times rat made contact with spout0.20.21.7-1.3-0.0-0.10.2-0.20.20.1-0.10.1
Lifetime Intake0.70.71.30.3-0.7-1.10.9-0.90.90.90.90.8
Liver weight, left0.60.93.8-1.9-1.11.1-0.41.1-0.4-0.3-0.60.4
Liver weight, right0.30.62.5-1.6-0.90.00.20.80.10.2-0.60.8
Locomotor activity1.82.85.9-2.4-0.5-1.41.9-1.81.81.81.51.3
Locomotor testing distance3.76.124.1-4.9-0.3-0.82.3-2.12.42.52.22.2
Locomotor testing rearing6.610.134.1-5.81.4-0.72.3-2.62.93.32.93.9
Locomotion in novel chamber1.51.83.7-0.2-1.11.9-1.81.9-1.4-1.1-1.0-0.5
Locomotion in novel chamber post-restriction1.72.15.4-1.81.32.3-1.71.4-1.3-0.8-1.10.0
Fecal boli incidents, locomotor time 11.82.03.50.40.91.8-1.91.5-1.7-1.4-1.4-1.0
Change in fecal boli incidents, locomotor task0.20.20.6-0.1-0.70.4-0.20.00.20.50.70.7
Time >=10cm from walls, locomotor time 10.80.93.11.81.1-0.3-0.3-0.20.20.70.91.3
Bouts of movement, locomotor time 11.11.15.41.52.30.8-1.10.3-0.8-0.4-0.20.1
Total resting periods, locomotor time 11.31.46.42.02.50.6-1.10.1-0.7-0.4-0.10.1
Rest time, locomotor task time 11.41.59.93.1-0.2-0.2-0.50.5-0.7-0.9-0.6-1.3
Distance moved, locomotor task time 15.05.521.5-4.6-0.1-1.12.3-2.32.22.21.71.9
Vertical activity count, locomotor time 10.60.61.5-1.20.90.8-0.40.3-0.6-0.7-0.9-1.0
Time >=10cm from walls, locomotor time 20.50.51.20.20.11.1-1.01.0-0.8-0.5-0.3-0.2
Bouts of movement, locomotor time 20.80.93.6-1.31.90.8-0.50.2-0.5-0.4-1.00.2
Total resting periods, locomotor time 20.60.73.7-0.81.90.8-0.60.1-0.5-0.3-0.70.3
Rest time, locomotor task time 21.82.013.03.6-0.40.5-1.41.1-1.0-0.8-0.1-0.4
Distance moved, locomotor task time 22.32.610.7-3.3-0.7-0.91.8-1.51.51.50.71.1
Vertical activity count, locomotor time 20.70.74.9-2.2-0.40.20.6-0.00.1-0.2-0.8-0.7
Light reinforcement 10.50.93.31.8-0.70.3-0.71.0-0.8-1.0-0.8-1.0
Light reinforcement 22.22.915.03.9-2.6-1.3-0.01.0-0.4-0.7-0.8-0.9
Bone: marrow area2.45.111.8-0.8-2.1-3.23.4-2.42.61.91.31.0
Bone: maximum diameter3.25.910.10.2-2.8-3.13.2-2.22.82.42.11.7
Bone: maximum force1.62.84.9-1.1-1.1-2.12.2-1.62.01.71.51.1
Bone: maximum moment2.03.56.0-1.4-1.3-2.32.5-1.82.21.91.71.4
Mean time between licks in bursts0.40.63.9-2.0-0.7-0.20.50.40.30.3-0.20.0
Mean num. licks in bursts1.21.42.40.3-1.4-1.51.5-1.51.31.11.00.6
Cd content in liver2.02.24.40.90.22.1-1.91.6-1.7-1.5-1.5-0.9
Co content in liver2.02.35.1-2.10.81.3-0.81.2-1.3-1.4-2.3-1.8
Cu content in liver1.01.21.7-0.9-0.9-1.21.2-0.91.31.31.21.0
Fe content in liver0.20.20.50.70.7-0.50.2-0.50.0-0.30.1-0.5
K content in liver0.60.61.5-0.70.6-0.80.7-1.20.70.70.80.3
Mg content in liver0.50.52.5-1.6-0.1-0.30.5-0.60.60.70.40.7
Mn content in liver0.60.61.20.8-0.50.7-0.80.7-0.8-0.9-0.7-1.1
Na content in liver2.22.45.8-0.62.1-1.81.5-2.41.41.11.50.3
Rb content in liver1.01.23.2-0.2-0.5-0.50.6-0.91.11.51.51.8
Se content in liver0.50.61.4-0.40.3-0.80.9-1.20.80.70.60.5
Sr content in liver0.40.41.3-0.70.2-0.50.9-1.10.50.4-0.4-0.1
Zn content in liver1.51.63.6-0.60.61.9-1.61.4-1.5-1.1-1.4-0.4
Bone: minimum diameter1.62.94.9-1.2-2.0-1.92.2-1.42.01.71.31.5
Time in familiar zone, hab. session 14.03.75.4-0.7-0.4-2.02.3-2.02.32.22.02.3
Time in novel zone, hab. session 13.73.66.30.80.61.8-2.11.9-2.3-2.1-2.0-2.5
Total zone transitions, hab. session 10.20.20.60.1-0.4-0.60.7-0.70.40.3-0.10.0
Total locomotion distance, hab. session 10.10.10.6-0.80.6-0.10.1-0.30.0-0.1-0.1-0.0
Locomotion velocity, hab. session 10.10.21.1-1.10.8-0.10.1-0.40.1-0.10.00.1
Time in familiar zone, hab. session 20.90.93.2-1.80.8-0.20.5-0.30.70.90.61.5
Time in novel zone, hab. session 21.01.04.42.1-0.30.3-0.70.2-0.8-0.9-0.6-1.4
Total zone transitions, hab. session 20.81.06.5-2.5-0.5-0.40.9-0.30.70.70.10.8
Total locomotion distance, hab. session 20.81.07.1-2.71.00.5-0.20.3-0.2-0.4-0.60.1
Locomotion velocity, hab. session 20.81.17.8-2.80.90.5-0.10.3-0.2-0.4-0.70.1
Novel to familiar place preference ratio0.30.41.00.5-0.7-0.80.4-0.50.50.41.00.1
Novelty place preference0.20.20.60.6-0.8-0.70.2-0.30.20.10.7-0.2
Time in novel zone, NPP test0.20.20.50.5-0.4-0.60.1-0.40.20.10.7-0.1
Total zone transitions, NPP test0.40.51.2-1.10.80.8-0.40.4-0.6-0.5-1.1-0.2
Total locomotion distance, NPP test0.81.16.1-2.50.0-0.20.5-0.20.70.70.51.4
Locomotion velocity, NPP test0.81.15.8-2.40.1-0.50.8-0.50.80.70.51.2
Intraocular pressure0.10.10.3-0.40.0-0.10.3-0.40.40.50.60.2
Delta distance traveled before/after self-admin0.80.92.6-0.7-0.41.4-1.21.6-0.8-0.5-0.70.4
Delta ambulatory time before/after self-admin2.12.35.7-0.7-0.22.2-1.92.4-1.6-1.2-1.5-0.1
Parametrial fat weight0.61.12.9-0.51.0-0.40.3-0.70.91.31.71.6
Pavlov. Cond. lever latency0.20.31.51.20.5-0.50.3-0.60.20.10.3-0.4
Pavlov. Cond. magazine entry latency0.70.94.1-2.00.9-0.40.6-0.90.70.60.50.9
Pavlov. Cond. change in total contacts0.40.42.3-1.5-0.60.20.10.20.20.40.10.8
Pavlov. Cond. index score0.40.53.8-1.90.30.20.2-0.20.20.3-0.00.8
Pavlov. Cond. latency score0.30.43.0-1.7-0.10.10.2-0.00.20.30.00.8
Pavlov. Cond. lever contacts0.30.42.5-1.6-0.70.00.30.10.20.3-0.30.5
Pavlov. Cond. magazine entry number0.50.71.01.00.20.7-0.80.9-0.9-0.9-0.7-0.8
Pavlov. Cond. intertrial magazine entries0.50.50.90.40.10.7-0.80.8-0.8-0.9-0.9-0.8
Pavlov. Cond. lever-magazine prob. diff.0.60.84.7-2.20.60.00.4-0.40.40.50.11.0
Pavlov. Cond. response bias0.70.83.0-1.70.3-0.50.8-0.80.80.80.61.1
Pavlov. Cond. lever latency1.31.83.31.41.21.8-1.81.3-1.5-1.2-1.0-0.5
Pavlov. Cond. magazine entry latency4.35.06.6-2.0-0.3-2.52.5-2.22.62.62.42.0
Pavlov. Cond. change in total contacts1.21.62.6-1.2-0.5-1.61.6-1.31.51.31.30.8
Pavlov. Cond. index score3.14.05.6-2.1-0.4-2.32.4-2.02.32.12.01.6
Pavlov. Cond. latency score2.53.14.3-1.9-0.3-2.02.1-1.82.01.91.81.4
Pavlov. Cond. lever contacts2.02.84.3-1.3-0.6-2.12.1-1.91.91.81.61.1
Pavlov. Cond. magazine entry number4.15.16.62.40.12.4-2.52.2-2.6-2.6-2.3-2.1
Pavlov. Cond. intertrial magazine entries0.50.71.70.00.51.3-1.11.0-0.9-0.7-0.8-0.2
Pavlov. Cond. lever-magazine prob. diff.3.24.15.9-2.1-0.3-2.32.4-2.12.32.22.01.6
Pavlov. Cond. response bias3.75.07.4-1.7-0.8-2.72.7-2.52.62.52.31.7
Time in closed arm before self-admin0.00.00.1-0.00.1-0.20.1-0.20.20.30.20.1
Time in closed arm after self-admin1.01.04.5-1.62.1-0.20.5-0.90.40.50.10.4
Time in open arm before self-admin0.30.40.90.4-1.0-0.30.30.00.50.60.90.9
Time in open arm after self-admin2.93.26.20.8-1.91.8-1.82.5-1.9-1.8-1.7-1.6
Bone: periosteal estimation3.06.312.8-0.8-3.0-3.33.6-2.42.92.21.61.3
Bone: periosteal perimeter0.91.55.10.7-2.3-1.41.5-1.01.21.00.60.5
Bone: post-yield work0.20.31.01.0-0.7-0.60.5-0.50.30.20.2-0.2
Progressive ratio test 1 active lever presses0.60.75.2-0.3-2.3-0.40.40.40.1-0.0-0.2-0.3
Progressive ratio test 1 breakpoint0.80.86.2-0.4-2.5-0.60.60.30.30.1-0.1-0.3
Progressive ratio test 1 inactive lever presses0.70.75.10.9-2.3-0.20.10.6-0.1-0.2-0.2-0.5
Progressive ratio test 2 active lever presses0.60.71.91.4-0.6-1.20.6-0.70.60.60.50.6
Progressive ratio test 2 breakpoint0.60.73.11.7-0.6-1.30.5-0.60.50.20.30.4
Progressive ratio test 2 inactive lever presses1.82.112.51.2-3.5-1.30.80.30.80.80.80.6
Incentive Sensitization - Responses2.72.810.23.21.7-2.11.0-2.10.90.60.80.2
Incentive Sensitization - Breakpoint2.82.810.23.21.9-2.00.9-2.10.90.70.90.4
Sum of active levers in priming session hrs 5-60.70.61.5-0.20.5-1.21.1-1.10.90.60.40.4
Progressive ratio0.30.41.6-1.3-0.6-0.10.6-0.30.60.50.60.3
Food seeking constrained by brief footshock3.44.26.9-2.6-0.4-1.42.5-2.32.42.12.21.4
Seeking ratio, punishment vs. effort0.70.91.30.5-0.2-1.10.9-1.01.01.11.01.0
Retroperitoneal fat weight0.61.95.52.31.01.2-1.71.3-1.4-1.3-0.9-0.7
Reaction time number correct0.50.81.8-0.31.30.7-0.80.6-0.9-1.0-1.0-0.8
Reaction time mean minus median1.52.04.1-2.02.0-0.81.1-1.41.21.21.41.0
Reaction time mean minus median AUC0.91.23.6-1.61.9-0.30.5-1.00.70.91.10.6
Reaction time num false alarms0.70.95.7-2.40.11.2-0.30.4-0.10.1-0.00.8
Reaction time num false alarms AUC0.81.16.6-2.6-0.41.4-0.40.6-0.4-0.4-0.40.0
Reaction time trials correct on left0.50.81.8-0.31.30.7-0.80.6-0.9-1.0-1.0-0.8
Reaction time trials on left0.50.71.8-0.41.40.7-0.80.6-0.9-1.0-0.9-0.7
Reaction time mean1.01.43.10.80.9-1.41.0-1.51.21.11.80.5
Reaction time mean AUC1.01.32.71.00.9-1.41.0-1.41.11.01.60.3
Median of all reaction times1.01.33.51.90.3-1.40.9-1.20.90.91.60.2
Reaction time omissions0.40.52.1-0.91.50.6-0.70.4-0.30.00.40.4
Reaction time false alarm rate0.70.96.1-2.5-0.91.00.10.10.20.20.10.5
Reaction time premature initiation rate0.30.51.00.30.40.0-0.60.8-0.7-1.0-0.6-1.0
Reaction time premature initiations0.60.91.7-0.21.20.3-0.90.9-1.0-1.3-0.9-1.2
Std. dev. reaction times1.42.03.8-1.91.8-0.81.1-1.51.31.21.50.9
Reaction time trials completed0.50.71.8-0.41.40.7-0.80.6-0.9-1.0-0.9-0.7
Reaction time trials AUC0.40.61.4-0.31.20.6-0.80.6-0.8-0.9-0.9-0.7
Run reversals in cocaine runway, females0.70.71.9-1.4-0.7-0.91.1-0.60.90.70.30.6
Run reversals in cocaine runway, males2.52.45.3-1.51.02.3-1.61.4-1.6-1.5-1.6-1.2
Latency to leave start box in cocaine runway2.02.25.31.2-2.30.6-0.81.4-1.2-1.5-1.4-2.1
Latency to leave start box in cocaine runway, F1.71.97.02.6-1.8-0.0-0.71.0-0.9-1.1-0.9-1.6
Latency to leave start box in cocaine runway, M1.41.33.7-0.9-1.90.7-0.20.8-0.7-1.1-1.1-1.7
Std. dev. time between licks in bursts1.51.812.9-3.6-1.00.50.10.90.00.2-0.70.6
Total sessions with >9 infusions0.20.20.6-0.00.8-0.30.4-0.60.1-0.2-0.3-0.5
Short access day 1 total inactive lever presses0.60.73.11.0-1.8-0.70.4-0.00.0-0.3-0.3-0.9
Short access day 10 total inactive lever presses0.60.74.92.20.1-1.10.2-0.50.20.00.2-0.3
Short access day 1 total infusions0.10.10.30.6-0.4-0.50.2-0.20.10.1-0.00.1
Short access day 10 total infusions0.40.41.8-1.3-1.30.10.40.30.40.40.20.1
Short access total infusions0.10.10.3-0.5-0.5-0.00.10.10.10.1-0.10.2
Short access day 1 locomotion0.10.20.40.20.60.6-0.60.0-0.20.00.30.5
Short access day 10 total locomotion2.42.79.30.43.1-1.01.1-2.41.31.21.90.6
Short access total locomotion0.70.82.0-0.81.4-0.20.6-1.00.80.71.10.8
One hour access (0.3 mA shock)1.72.03.21.6-1.7-1.81.1-0.71.21.31.51.4
Compulsive drug intake0.20.20.7-0.8-0.1-0.00.3-0.20.40.50.50.4
One hour access (shock baseline)1.31.53.31.8-0.4-1.60.9-1.11.01.21.21.2
Social response proportion2.02.213.43.7-1.8-0.8-0.40.8-0.6-0.6-0.6-0.9
Social responses2.12.74.8-0.3-2.2-1.92.0-1.41.81.61.80.8
Social time4.55.932.25.7-1.50.2-1.31.4-1.7-1.9-1.3-2.7
Soleus weight0.10.31.0-1.0-0.2-0.50.50.10.1-0.3-0.5-0.7
Bone: stiffness2.43.86.2-0.5-1.2-2.52.4-1.92.32.12.11.6
Tibialis anterior weight0.00.10.40.60.6-0.10.0-0.1-0.2-0.4-0.2-0.3
Time to tail flick, vehicle, before self-admin1.01.07.0-0.32.60.8-0.8-0.2-0.6-0.2-0.40.3
Time to tail flick, vehicle, after self-admin0.30.30.70.50.80.8-0.80.4-0.30.20.30.6
Time to tail flick, test, before self-admin0.60.62.11.4-0.9-0.40.10.3-0.3-0.7-0.4-1.3
Time to tail flick, test, after self-admin0.60.62.10.8-1.50.3-0.51.1-0.5-0.4-0.5-0.5
Delta time to tail flick, vehicle, before/after SA0.40.41.3-0.1-1.20.7-0.51.0-0.4-0.3-0.2-0.1
Delta time to tail flick, test, before/after SA0.80.71.9-0.60.21.4-1.21.1-0.7-0.1-0.30.7
Tibia length0.92.74.0-0.9-1.9-1.41.6-1.21.82.01.72.0
Ambulatory time before self-admin0.50.53.4-0.51.80.5-0.4-0.2-0.2-0.2-0.10.2
Ambulatory time after self-admin0.91.02.4-0.41.51.2-1.21.1-0.9-0.7-0.90.1
Bone: tissue strength1.61.52.4-1.61.2-1.21.1-1.41.21.21.30.8
Total heroin consumption0.30.31.11.00.7-0.1-0.30.1-0.4-0.7-0.5-0.6
Bone: trabecular number0.50.82.91.70.2-0.50.4-0.90.60.71.00.8
Bone: trabecular spacing1.21.63.1-0.2-0.21.5-1.31.8-1.4-1.4-1.5-1.0
Bone: trabecular thickness1.41.72.7-0.2-1.3-1.61.6-1.51.51.21.21.1
Bone: trabecular tissue density1.52.14.0-2.0-0.7-1.51.8-1.41.61.60.91.1
Water consumed over 24 hours0.70.81.3-1.1-0.1-0.70.9-0.91.01.00.91.1
Number of responses in last shaping day1.11.28.0-0.8-2.80.3-0.11.10.10.40.10.5