Hub : Genes

Fmnl2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL alternative TSS XM_017592149.2 0.13 0.12 9.0e-03 0.03 0.05 0.08 0.03 7.4e-02 2.1e-02 5.5e-03 6.5e-02
2 BLA gene expression Fmnl2 0.31 0.21 9.8e-15 0.23 0.28 0.25 0.26 1.9e-12 2.9e-15 1.0e-13 5.9e-14
3 Brain mRNA stability Fmnl2 0.04 0.04 1.2e-03 0.02 0.03 0.02 0.02 4.4e-03 1.1e-03 6.2e-03 3.8e-03
4 IL gene expression Fmnl2 0.2 0.16 9.5e-04 0.06 0.1 0.09 0.07 1.4e-02 2.5e-03 3.7e-03 8.2e-03
5 PL isoform ratio XM_039106790.1 0.02 0.02 9.7e-03 0.01 0.02 0.01 0.01 2.8e-02 5.3e-03 1.8e-02 1.9e-02
6 Brain gene expression Fmnl2 0.22 0.15 0.0e+00 0.2 0.2 0.2 0.21 2.0e-18 2.2e-18 4.4e-18 5.9e-19
7 PL gene expression Fmnl2 0.25 0.21 0.0e+00 0.22 0.22 0.22 0.21 3.0e-23 1.5e-23 2.7e-23 7.8e-23
8 NAcc gene expression Fmnl2 0.15 0.11 0.0e+00 0.15 0.16 0.15 0.15 5.8e-17 1.9e-18 3.9e-17 2.3e-17
9 OFC gene expression Fmnl2 0.39 0.22 1.4e-05 0.14 0.13 0.06 0.09 4.4e-04 6.3e-04 1.4e-02 4.6e-03
10 RMTg alternative TSS XM_017592149.2 0.14 0.12 7.1e-03 0 0.01 0.02 0.02 2.5e-01 1.4e-01 7.3e-02 1.2e-01
11 RMTg alternative TSS XM_039106786.1 0.14 0.13 7.1e-03 0 0.01 0.02 0.01 2.6e-01 1.6e-01 8.5e-02 1.5e-01
12 PL isoform ratio XM_039106789.1 0.04 0.04 1.7e-04 0.03 0.03 0.03 0.03 1.7e-04 1.7e-04 1.9e-04 2.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density2.03.410.63.2-1.01.0-1.01.0-1.6-1.0-1.01.12.9-2.82.0
Area under the delay curve3.23.44.7-0.3-1.81.8-1.81.8-2.1-1.7-1.81.72.2-2.22.0
BMI with tail0.31.112.53.50.1-0.10.1-0.1-0.40.10.10.1-0.00.00.1
BMI without tail0.91.88.12.81.2-1.21.2-1.20.91.21.2-1.1-1.01.0-1.1
Body weight0.21.02.41.30.8-0.80.8-0.81.10.70.8-0.7-1.61.5-0.8
Weight adjusted by age0.30.40.7-0.1-0.50.5-0.50.5-0.6-0.5-0.50.60.8-0.80.8
Bone surface0.81.49.93.1-0.30.3-0.30.3-0.6-0.3-0.30.41.5-1.51.0
Bone volume1.52.55.42.3-1.11.1-1.11.1-1.4-1.1-1.11.22.3-2.31.8
Breakpoint value in progressive ratio session0.00.00.10.10.2-0.20.2-0.20.10.20.2-0.2-0.30.30.0
Number of licking bursts1.61.98.7-2.9-1.41.3-1.31.3-0.9-1.3-1.31.3-0.40.30.5
Context. condit. distance diff. score0.00.10.1-0.2-0.20.2-0.20.2-0.1-0.2-0.20.3-0.30.3-0.0
Locomotion velocity, session 10.10.10.6-0.80.2-0.20.2-0.20.40.20.2-0.2-0.40.4-0.3
Locomotion distance, session 10.20.30.40.30.6-0.60.6-0.60.30.60.6-0.6-0.30.4-0.5
Locomotion velocity, session 20.40.50.7-0.8-0.80.7-0.70.7-0.3-0.8-0.70.80.5-0.50.6
Locomotion distance, session 20.81.17.92.80.8-0.80.8-0.7-0.00.80.7-0.90.7-0.7-0.0
Locomotion velocity, session 30.40.53.8-1.9-0.30.3-0.30.3-0.2-0.3-0.30.4-0.80.7-0.2
Locomotion distance, session 30.10.10.40.60.3-0.30.3-0.3-0.00.20.3-0.2-0.10.1-0.2
Stereotopy head waving bouts, day 30.91.01.40.81.2-1.11.1-1.10.71.21.1-1.2-0.70.8-1.0
Stereotopy head waving duration, day 31.92.33.81.91.7-1.61.6-1.61.21.71.6-1.7-0.80.9-1.3
Locomotion velocity, session 71.92.02.50.81.5-1.51.5-1.51.61.51.5-1.4-1.31.3-1.5
Locomotion distance, session 70.70.91.3-0.40.9-0.90.9-0.91.10.91.0-0.8-1.11.1-1.1
Stereotopy head waving bouts, day 70.20.22.01.40.1-0.10.1-0.1-0.20.10.1-0.10.2-0.20.0
Stereotopy head waving duration, day 70.60.75.12.3-0.30.3-0.30.3-0.8-0.3-0.40.30.9-0.90.7
Locomotion velocity, session 80.20.21.81.40.2-0.20.2-0.2-0.40.20.2-0.20.1-0.10.0
Locomotion distance, session 80.30.52.61.60.6-0.60.6-0.60.20.60.6-0.6-0.20.2-0.4
Degree of sensitization distance0.50.51.9-1.40.4-0.40.4-0.40.90.40.4-0.4-0.80.8-0.7
Degree of sensitization stereotypy0.20.30.4-0.1-0.60.6-0.60.6-0.6-0.6-0.60.60.2-0.20.4
Conditioned locomotion2.42.820.74.50.00.0-0.00.0-1.20.0-0.00.02.3-2.21.3
Cocaine response after cond. corrected0.20.20.4-0.6-0.50.5-0.50.5-0.6-0.6-0.50.6-0.30.30.1
Cocaine response after cond. not corrected0.20.20.7-0.50.3-0.30.3-0.30.30.20.3-0.2-0.80.8-0.5
Cocaine response before conditioning1.01.22.4-0.31.1-1.11.1-1.11.61.11.1-1.1-0.80.8-1.1
Saline control response0.20.20.70.80.4-0.40.4-0.40.40.40.4-0.40.6-0.50.2
Bone: connectivity density1.11.811.93.5-0.20.2-0.20.2-0.7-0.2-0.20.31.9-1.91.1
Bone: cortical apparent density0.20.33.1-1.8-0.10.1-0.10.10.2-0.1-0.10.1-0.30.3-0.1
Bone: cortical area0.71.01.81.21.1-1.11.1-1.11.31.11.1-1.0-0.20.3-0.6
Bone: cortical porosity0.50.62.71.7-0.60.6-0.60.6-0.8-0.6-0.60.50.6-0.60.4
Bone: cortical porosity0.40.52.61.6-0.60.5-0.50.5-0.7-0.6-0.60.50.5-0.50.3
Bone: cortical thickness0.81.32.00.71.2-1.21.2-1.21.41.21.2-1.1-1.01.0-1.2
Bone: cortical thickness0.91.12.2-0.90.8-0.80.8-0.81.30.80.8-0.7-1.51.5-1.3
Bone: cortical tissue density0.20.33.4-1.8-0.20.2-0.20.20.1-0.2-0.20.2-0.30.3-0.0
Condit. Reinf. active minus inactive responses3.94.435.46.01.6-1.51.5-1.50.31.51.5-1.60.8-0.7-0.4
Condit. Reinf. active-inactive response ratio2.42.622.34.71.1-1.11.1-1.10.31.11.1-1.10.4-0.3-0.3
Condit. Reinf. active responses4.04.940.36.31.6-1.51.5-1.50.21.51.4-1.51.2-1.1-0.2
Condit. Reinf. inactive responses0.20.20.80.90.4-0.40.4-0.40.00.40.4-0.40.4-0.4-0.0
Incentive salience index mean4.45.443.06.61.7-1.71.7-1.70.51.71.6-1.70.9-0.8-0.4
Condit. Reinf. lever presses1.01.412.83.60.4-0.40.3-0.3-0.10.30.3-0.31.2-1.10.4
Condit. Reinf. active minus inactive responses4.35.410.83.32.5-2.52.5-2.52.22.52.5-2.5-1.11.2-1.8
Condit. Reinf. active-inactive response ratio6.36.612.53.52.8-2.82.7-2.72.42.82.7-2.8-1.41.4-2.1
Condit. Reinf. active responses2.23.14.92.21.9-1.91.9-1.91.81.91.9-1.9-0.91.0-1.3
Condit. Reinf. inactive responses0.50.62.7-1.6-0.70.7-0.70.7-0.4-0.7-0.70.70.1-0.10.5
Condit. Reinf. lever presses1.01.35.52.41.2-1.21.2-1.20.81.21.1-1.20.4-0.40.1
Condit. Reinf. lever reinforcers received2.33.36.12.52.0-2.02.0-2.01.82.02.0-2.0-0.80.8-1.2
Conditioned reinforcement - actives0.60.60.70.10.8-0.80.8-0.80.80.80.8-0.8-0.80.8-0.5
Conditioned reinforcement - inactives0.50.50.80.90.8-0.80.8-0.80.70.80.8-0.8-0.50.6-0.4
Conditioned locomotion0.00.00.1-0.3-0.10.1-0.10.1-0.1-0.1-0.10.1-0.10.10.4
Patch foraging indifference point 0 sec0.20.41.3-1.2-0.70.7-0.70.7-0.1-0.7-0.70.50.2-0.20.2
Patch foraging indifference point AUC2.93.314.23.81.7-1.71.7-1.71.41.71.7-1.9-0.60.7-1.3
Delay disc. indifference point, 0s delay2.93.24.1-0.3-1.81.8-1.81.8-2.0-1.7-1.81.72.0-2.02.0
Delay disc. indifference point, 16s delay3.33.44.3-1.1-1.81.9-1.91.9-2.1-1.8-1.91.71.9-1.92.0
Delay disc. indifference point, 2s delay4.95.57.60.2-2.32.4-2.42.4-2.7-2.3-2.42.22.7-2.72.3
Delay disc. indifference point, 24s delay1.41.41.6-0.8-1.21.2-1.21.2-1.2-1.2-1.21.21.2-1.21.3
Delay disc. indifference point, 4s delay3.33.54.5-0.5-1.81.9-1.91.9-2.1-1.8-1.91.82.1-2.12.1
Delay disc. indifference point, 8s delay1.41.52.0-0.0-1.21.2-1.21.2-1.4-1.2-1.21.21.4-1.41.3
Indifference point function ln k0.30.41.3-1.1-0.60.6-0.60.6-0.5-0.6-0.60.70.3-0.30.5
Indifference point function log k0.30.41.3-1.1-0.60.6-0.60.6-0.5-0.6-0.60.70.3-0.30.5
Patch foraging total patch changes 0 sec0.30.50.9-0.9-0.80.8-0.80.8-0.2-0.8-0.80.60.4-0.50.4
Patch foraging total patch changes 12 sec0.50.61.91.30.5-0.50.5-0.50.80.60.5-0.9-0.60.6-1.4
Patch foraging total patch changes 18 sec0.20.20.70.3-0.30.4-0.40.4-0.2-0.3-0.3-0.00.8-0.80.3
Patch foraging total patch changes 24 sec1.11.36.22.50.9-0.90.9-0.90.71.00.9-1.3-0.70.7-1.0
Patch foraging total patch changes 6 sec0.30.51.4-1.2-0.60.6-0.60.6-0.1-0.6-0.60.20.8-0.80.9
Patch foraging time to switch 0 sec2.13.310.2-3.2-1.71.7-1.71.7-1.6-1.7-1.71.51.5-1.51.5
Patch foraging water rate 0 sec1.32.010.43.21.3-1.31.3-1.31.11.31.3-1.1-0.50.5-1.0
Patch foraging water rate 12 sec1.82.83.92.01.9-1.91.9-1.91.41.81.9-1.7-1.21.2-1.0
Patch foraging water rate 18 sec0.91.21.8-0.41.1-1.11.1-1.11.31.11.1-0.8-1.41.4-0.9
Patch foraging water rate 24 sec0.60.91.3-0.51.0-1.01.0-1.01.10.91.0-0.7-1.11.1-0.6
Patch foraging water rate 6 sec0.91.21.40.61.2-1.21.2-1.21.21.11.2-1.0-1.21.2-1.1
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.3-0.30.3-0.30.3-0.3-0.4-0.30.50.3-0.30.4
Distance traveled before self-admin1.11.21.31.11.2-1.21.2-1.21.01.21.2-1.2-1.01.0-1.0
Distance traveled after self-admin0.40.52.81.70.7-0.70.7-0.70.40.60.7-0.50.1-0.0-0.1
Extensor digitorum longus weight0.62.412.63.51.5-1.51.5-1.50.91.41.5-1.3-0.20.3-0.9
Bone: elastic displacement1.31.52.51.01.2-1.31.3-1.31.61.21.3-1.2-1.01.1-1.2
Bone: elastic work2.93.75.61.32.0-2.02.0-2.02.41.92.0-1.9-1.71.8-2.0
Bone: endosteal estimation0.40.94.52.10.1-0.00.0-0.0-0.20.0-0.0-0.01.6-1.51.1
Bone: endosteal perimeter0.10.31.0-0.30.6-0.60.6-0.61.00.60.6-0.50.3-0.30.3
Epididymis fat weight0.92.13.5-0.51.4-1.41.4-1.41.61.41.5-1.4-1.91.9-1.2
Delta time in closed arm before/after self-admin0.20.20.30.4-0.40.4-0.40.4-0.6-0.4-0.40.40.5-0.50.3
Delta time in open arm before/after self-admin0.10.10.20.40.4-0.40.4-0.40.20.40.4-0.3-0.10.1-0.0
Diff in mean of infusions in LGA sessions0.10.10.20.30.2-0.30.2-0.30.20.20.3-0.2-0.50.4-0.3
Delay discount exponential model param2.72.84.10.21.6-1.61.6-1.61.91.61.7-1.6-2.02.0-1.8
Extinction: sum of active levers before priming0.00.00.20.10.2-0.20.2-0.20.00.20.1-0.20.1-0.10.4
Active lever presses in extinction session 60.20.20.90.90.4-0.40.4-0.40.20.30.3-0.3-0.20.3-0.3
Bone: final force1.62.64.21.11.9-1.91.9-1.92.01.91.9-1.8-0.50.5-1.1
Bone: final moment1.21.93.30.81.6-1.61.6-1.61.81.61.6-1.6-0.40.4-0.9
Food consumed during 24 hour testing period1.92.323.14.80.3-0.20.2-0.2-0.50.20.2-0.21.4-1.40.7
Glucose0.60.81.70.10.9-0.90.9-0.90.90.90.9-0.8-1.31.3-0.7
Heart weight1.21.710.4-3.2-1.11.1-1.11.1-0.5-1.1-1.11.0-0.40.31.1
Delay discount hyperbolic model param3.53.75.40.21.9-1.91.9-1.92.21.81.9-1.8-2.32.3-2.1
Intermittent access intake day 1-15 change1.31.32.3-0.5-1.11.1-1.11.1-1.1-1.1-1.11.11.3-1.31.5
Intermittent access intake escalation0.70.61.5-0.2-0.70.7-0.70.7-0.8-0.7-0.70.80.9-0.91.2
Intermittent access intake escalation 20.30.30.6-0.2-0.50.5-0.50.5-0.6-0.6-0.60.60.7-0.70.8
Intermitt. access day 1 inactive lever presses2.12.32.61.31.6-1.61.6-1.61.51.61.6-1.5-1.41.4-1.4
Intermitt. access day 15 inactive lever presses8.49.210.42.63.2-3.23.2-3.23.13.23.2-3.1-2.72.7-2.9
Intermitt. access escalation Index0.70.60.9-0.3-0.90.9-0.90.9-0.8-0.9-0.90.90.6-0.60.5
Intermittent access day 1 total infusions0.70.81.00.70.9-0.90.9-0.90.90.90.9-0.9-1.01.0-0.8
Intermittent access day 15 total infusions0.10.10.40.60.3-0.30.3-0.30.30.30.3-0.3-0.20.20.2
Intermittent access terminal intake (last 3 days)0.50.50.80.90.8-0.80.8-0.80.70.80.8-0.7-0.40.5-0.3
Intermittent access total infusions0.10.10.40.60.3-0.30.3-0.30.30.30.3-0.3-0.30.30.0
Intermittent access day 1 locomotion0.40.50.70.50.7-0.70.7-0.70.70.80.7-0.9-0.70.7-0.5
Intermittent access day 15 total locomotion0.70.70.90.80.9-0.90.9-0.90.90.90.9-0.9-0.70.7-0.5
Intermittent access total locomotion0.40.40.60.60.7-0.70.7-0.70.60.70.7-0.8-0.60.6-0.4
Intermittent access standard deviation0.10.20.90.9-0.00.1-0.10.1-0.3-0.1-0.10.10.5-0.50.6
Left kidney weight2.26.19.4-1.42.4-2.42.4-2.43.12.32.4-2.2-3.13.1-1.9
Right kidney weight0.51.42.5-1.11.2-1.21.2-1.21.61.01.2-0.9-1.41.4-0.2
Cocaine induced anxiety1.61.82.8-0.11.3-1.31.3-1.31.61.31.4-1.1-1.71.7-1.4
Post-drug Anxiety1.82.02.70.01.4-1.41.4-1.41.61.41.4-1.3-1.61.6-1.5
Baseline Anxiety1.21.31.6-0.6-1.21.2-1.21.2-1.2-1.2-1.21.11.2-1.20.9
Tail length0.20.63.4-1.80.4-0.40.4-0.40.90.40.4-0.5-0.80.8-0.4
Length with tail0.30.95.8-2.4-0.10.0-0.00.00.9-0.1-0.0-0.0-1.41.4-0.7
Length without tail0.20.41.0-1.0-0.80.7-0.70.7-0.3-0.8-0.70.8-0.10.10.2
Times rat made contact with spout0.40.41.0-0.90.6-0.60.6-0.61.00.60.6-0.6-0.60.6-0.4
Lifetime Intake0.00.00.10.30.2-0.20.2-0.20.10.20.2-0.2-0.10.10.2
Liver weight, left1.11.76.42.51.2-1.21.2-1.20.71.21.2-1.2-0.90.9-1.3
Liver weight, right1.93.216.1-4.0-0.0-0.10.0-0.10.70.00.10.1-3.02.9-1.9
Locomotor activity1.11.72.20.61.4-1.41.4-1.41.51.41.4-1.4-1.31.3-0.9
Locomotor testing distance2.54.16.1-0.32.0-2.02.0-2.02.42.02.0-1.9-2.52.5-2.1
Locomotor testing rearing5.68.710.41.73.0-3.03.0-3.03.23.03.0-3.0-2.92.9-3.2
Locomotion in novel chamber0.20.31.3-1.2-0.50.5-0.50.5-0.3-0.5-0.40.50.2-0.30.7
Locomotion in novel chamber post-restriction2.42.94.00.4-1.61.6-1.61.6-2.0-1.6-1.61.82.0-2.01.9
Fecal boli incidents, locomotor time 10.20.30.4-0.00.5-0.50.5-0.50.40.60.6-0.3-0.50.5-0.7
Change in fecal boli incidents, locomotor task1.81.72.20.3-1.51.5-1.51.5-1.4-1.5-1.51.11.2-1.21.0
Time >=10cm from walls, locomotor time 10.20.22.21.5-0.10.1-0.10.1-0.3-0.2-0.10.3-0.0-0.0-0.3
Bouts of movement, locomotor time 10.50.60.9-0.7-0.80.8-0.80.8-0.6-0.9-0.80.90.6-0.60.9
Total resting periods, locomotor time 11.01.12.4-1.5-1.11.0-1.11.0-0.8-1.1-1.01.10.7-0.71.2
Rest time, locomotor task time 12.62.93.9-1.7-1.91.9-1.91.9-1.4-2.0-1.91.91.0-1.01.5
Distance moved, locomotor task time 11.71.93.20.71.6-1.51.5-1.51.21.61.5-1.8-0.90.9-1.1
Vertical activity count, locomotor time 10.80.82.21.50.9-0.90.9-0.90.71.00.9-1.0-0.50.5-1.0
Time >=10cm from walls, locomotor time 21.81.93.11.81.4-1.41.4-1.41.01.41.4-1.4-1.11.2-1.5
Bouts of movement, locomotor time 25.35.77.7-1.2-2.52.5-2.52.5-2.4-2.5-2.52.82.3-2.32.5
Total resting periods, locomotor time 24.95.27.6-1.1-2.42.4-2.42.4-2.3-2.5-2.42.82.1-2.12.3
Rest time, locomotor task time 22.02.33.2-0.4-1.61.6-1.61.6-1.6-1.6-1.61.81.3-1.41.5
Distance moved, locomotor task time 24.14.76.31.12.4-2.42.4-2.42.22.42.4-2.5-1.81.8-2.0
Vertical activity count, locomotor time 20.50.50.7-0.10.7-0.70.7-0.70.90.70.7-0.6-0.70.7-0.7
Light reinforcement 10.91.76.9-2.60.5-0.60.6-0.61.50.50.6-0.7-1.91.8-1.3
Light reinforcement 20.50.71.9-1.40.7-0.70.7-0.71.00.70.7-0.7-1.01.0-0.6
Bone: marrow area0.40.84.42.10.1-0.10.1-0.0-0.20.00.0-0.01.5-1.51.1
Bone: maximum diameter0.51.05.72.40.3-0.30.3-0.3-0.10.30.3-0.21.5-1.50.9
Bone: maximum force1.01.83.51.01.5-1.51.5-1.51.91.51.5-1.5-0.40.4-0.9
Bone: maximum moment0.71.22.40.81.2-1.21.2-1.21.61.21.2-1.2-0.20.2-0.6
Mean time between licks in bursts1.11.613.63.70.8-0.80.8-0.80.30.80.8-0.8-0.10.2-0.6
Mean num. licks in bursts2.02.44.82.21.8-1.81.8-1.71.61.71.7-1.70.00.1-0.7
Cd content in liver1.61.812.4-3.5-0.60.5-0.50.50.3-0.5-0.50.7-1.71.6-0.9
Co content in liver0.91.12.1-1.4-1.01.0-1.01.0-1.0-1.0-1.01.00.8-0.81.0
Cu content in liver0.60.84.0-2.0-0.80.8-0.80.8-0.4-0.8-0.80.7-0.40.4-0.0
Fe content in liver2.53.16.62.6-1.61.6-1.61.6-2.3-1.5-1.61.31.9-1.91.2
K content in liver0.10.10.2-0.3-0.50.4-0.40.4-0.4-0.4-0.40.4-0.0-0.00.2
Mg content in liver0.00.00.10.3-0.10.1-0.10.1-0.2-0.0-0.1-0.1-0.30.2-0.2
Mn content in liver0.40.52.71.60.6-0.60.5-0.60.40.50.5-0.5-0.40.4-0.5
Na content in liver2.52.74.21.91.8-1.81.8-1.81.61.91.8-2.0-0.60.6-1.2
Rb content in liver0.50.71.1-0.8-0.70.7-0.70.7-0.9-0.7-0.70.61.1-1.01.0
Se content in liver1.11.34.0-2.0-1.31.2-1.21.2-0.6-1.2-1.21.2-0.80.7-0.2
Sr content in liver1.61.511.4-3.4-0.90.9-0.90.9-0.1-0.9-0.90.9-0.40.30.2
Zn content in liver1.61.712.4-3.5-1.11.1-1.11.1-0.6-1.0-1.10.9-0.20.10.3
Bone: minimum diameter0.30.52.51.60.0-0.00.0-0.00.0-0.0-0.00.11.2-1.10.9
Time in familiar zone, hab. session 12.42.222.24.70.7-0.70.7-0.7-0.50.70.6-0.70.8-0.70.1
Time in novel zone, hab. session 13.13.027.2-5.2-1.01.0-1.00.90.2-1.0-0.91.0-1.00.9-0.0
Total zone transitions, hab. session 10.30.40.7-0.00.6-0.60.6-0.60.20.60.6-0.6-0.80.8-0.7
Total locomotion distance, hab. session 10.60.93.81.91.0-0.91.0-0.90.21.00.9-0.90.00.0-0.5
Locomotion velocity, hab. session 10.20.31.21.10.6-0.60.6-0.60.00.60.6-0.60.2-0.2-0.2
Time in familiar zone, hab. session 20.60.60.9-0.7-0.80.8-0.80.8-0.9-0.8-0.80.80.5-0.60.7
Time in novel zone, hab. session 21.21.28.8-3.00.0-0.10.1-0.10.90.10.1-0.1-1.41.3-0.8
Total zone transitions, hab. session 22.53.33.90.51.9-1.91.9-1.91.61.91.9-1.9-2.02.0-2.0
Total locomotion distance, hab. session 20.40.61.9-1.40.5-0.50.5-0.50.60.50.5-0.5-1.01.0-0.8
Locomotion velocity, hab. session 20.50.71.0-0.70.8-0.80.8-0.80.80.90.8-0.8-1.01.0-0.9
Novel to familiar place preference ratio0.10.10.10.20.3-0.30.3-0.2-0.10.30.2-0.30.3-0.30.0
Novelty place preference0.10.10.30.30.2-0.20.2-0.2-0.20.20.2-0.20.5-0.50.2
Time in novel zone, NPP test0.10.10.2-0.3-0.00.0-0.00.0-0.30.0-0.0-0.10.5-0.40.2
Total zone transitions, NPP test0.30.41.3-1.20.3-0.30.3-0.30.40.30.3-0.3-1.11.1-0.7
Total locomotion distance, NPP test0.71.06.2-2.50.3-0.40.4-0.40.80.30.4-0.3-1.31.3-0.9
Locomotion velocity, NPP test0.50.83.5-1.90.5-0.50.5-0.50.80.50.5-0.5-1.11.1-0.8
Intraocular pressure2.33.39.43.11.8-1.81.8-1.81.51.71.8-1.7-1.51.5-1.4
Delta distance traveled before/after self-admin0.10.10.50.7-0.00.0-0.00.0-0.1-0.0-0.00.10.5-0.40.4
Delta ambulatory time before/after self-admin0.00.00.00.20.1-0.10.1-0.10.10.10.10.00.1-0.10.2
Parametrial fat weight0.71.42.21.51.3-1.31.3-1.31.01.31.3-1.3-0.70.7-0.7
Pavlov. Cond. lever latency2.02.620.9-4.6-1.11.1-1.11.1-0.6-1.1-1.01.0-1.01.00.1
Pavlov. Cond. magazine entry latency0.30.44.0-2.0-0.20.2-0.20.20.1-0.2-0.20.1-0.50.5-0.2
Pavlov. Cond. change in total contacts2.93.15.92.41.9-1.91.9-1.91.61.91.9-1.9-1.01.1-1.5
Pavlov. Cond. index score0.40.53.31.80.6-0.60.6-0.50.40.60.5-0.60.4-0.3-0.1
Pavlov. Cond. latency score0.60.85.12.30.7-0.70.7-0.70.60.70.7-0.70.4-0.4-0.1
Pavlov. Cond. lever contacts1.11.312.23.50.4-0.40.4-0.4-0.10.40.4-0.31.2-1.20.4
Pavlov. Cond. magazine entry number0.20.20.60.8-0.30.3-0.30.3-0.5-0.3-0.30.30.6-0.60.5
Pavlov. Cond. intertrial magazine entries1.51.813.03.60.00.0-0.00.0-0.7-0.0-0.10.01.9-1.81.0
Pavlov. Cond. lever-magazine prob. diff.0.60.85.32.30.7-0.70.7-0.70.40.70.7-0.70.4-0.4-0.1
Pavlov. Cond. response bias0.20.20.30.60.5-0.50.5-0.50.50.50.5-0.5-0.20.2-0.3
Pavlov. Cond. lever latency0.91.27.9-2.8-0.80.8-0.80.8-0.4-0.8-0.80.8-0.90.8-0.1
Pavlov. Cond. magazine entry latency0.70.82.81.6-0.10.1-0.10.1-0.6-0.1-0.10.11.7-1.61.2
Pavlov. Cond. change in total contacts0.81.11.80.21.2-1.21.2-1.21.31.21.2-1.3-0.30.3-0.5
Pavlov. Cond. index score0.60.73.41.90.6-0.60.6-0.50.20.60.5-0.61.1-1.10.7
Pavlov. Cond. latency score0.40.52.01.40.2-0.20.2-0.1-0.20.20.1-0.21.3-1.20.9
Pavlov. Cond. lever contacts1.82.511.53.41.6-1.51.5-1.51.01.61.5-1.60.6-0.5-0.3
Pavlov. Cond. magazine entry number0.80.94.6-2.1-0.80.8-0.80.7-0.4-0.8-0.70.8-1.11.0-0.4
Pavlov. Cond. intertrial magazine entries0.71.01.7-1.30.8-0.80.8-0.81.10.80.8-0.8-1.31.3-0.9
Pavlov. Cond. lever-magazine prob. diff.0.50.73.21.80.7-0.70.7-0.70.30.70.7-0.70.9-0.80.4
Pavlov. Cond. response bias1.82.511.83.41.5-1.51.5-1.51.01.51.5-1.50.8-0.7-0.1
Time in closed arm before self-admin0.70.81.2-0.2-0.90.9-0.90.9-1.0-1.0-1.01.00.8-0.81.1
Time in closed arm after self-admin1.71.72.2-0.2-1.41.4-1.41.4-1.5-1.4-1.41.41.3-1.31.4
Time in open arm before self-admin3.03.34.90.61.8-1.81.8-1.81.91.91.8-1.9-1.81.8-2.2
Time in open arm after self-admin1.82.02.40.91.5-1.51.5-1.51.41.51.5-1.5-1.21.2-1.5
Bone: periosteal estimation0.51.05.82.40.8-0.80.8-0.80.70.80.8-0.70.9-0.90.3
Bone: periosteal perimeter0.30.51.8-0.40.8-0.80.8-0.81.30.70.8-0.70.3-0.20.1
Bone: post-yield work0.81.16.5-2.6-0.90.9-0.90.9-0.3-0.9-0.90.90.1-0.20.6
Progressive ratio test 1 active lever presses0.10.10.20.40.4-0.40.4-0.40.40.40.4-0.3-0.30.3-0.2
Progressive ratio test 1 breakpoint0.10.10.20.40.4-0.40.4-0.40.40.40.5-0.3-0.30.3-0.2
Progressive ratio test 1 inactive lever presses3.03.33.91.51.9-1.91.9-1.91.81.91.9-2.0-1.51.5-1.7
Progressive ratio test 2 active lever presses1.11.11.40.51.2-1.21.2-1.21.11.21.2-1.2-1.01.0-0.8
Progressive ratio test 2 breakpoint0.80.91.10.41.0-1.01.0-1.01.01.01.0-1.0-0.90.9-0.7
Progressive ratio test 2 inactive lever presses0.91.01.20.81.1-1.11.1-1.11.11.11.1-1.1-0.80.9-0.6
Incentive Sensitization - Responses0.80.81.10.31.0-1.01.0-1.01.01.01.0-1.0-0.80.8-0.6
Incentive Sensitization - Breakpoint0.90.91.20.41.0-1.01.0-1.01.01.01.0-1.1-0.80.8-0.7
Sum of active levers in priming session hrs 5-60.60.61.60.1-0.60.7-0.70.7-0.9-0.7-0.70.61.0-1.01.3
Progressive ratio0.91.14.12.00.9-0.90.9-0.90.80.90.9-0.8-0.80.8-1.1
Food seeking constrained by brief footshock10.012.314.31.53.7-3.73.7-3.73.73.83.7-3.8-3.43.4-3.3
Seeking ratio, punishment vs. effort0.40.42.2-1.50.5-0.50.5-0.50.60.50.5-0.6-0.60.6-0.2
Retroperitoneal fat weight0.10.20.3-0.50.5-0.50.5-0.50.60.40.5-0.4-0.50.50.3
Reaction time number correct1.42.02.70.31.5-1.51.5-1.51.61.41.5-1.3-1.61.6-1.4
Reaction time mean minus median0.40.64.5-2.1-0.60.6-0.50.5-0.3-0.5-0.50.6-0.10.00.3
Reaction time mean minus median AUC0.60.76.9-2.6-0.00.0-0.00.00.2-0.0-0.00.0-0.90.9-0.4
Reaction time num false alarms2.53.48.83.01.8-1.81.8-1.81.71.81.8-1.7-1.41.4-1.7
Reaction time num false alarms AUC2.93.97.02.62.0-2.02.0-2.01.92.02.0-1.9-1.61.6-1.8
Reaction time trials correct on left1.42.02.70.31.5-1.51.5-1.51.61.41.5-1.3-1.61.6-1.4
Reaction time trials on left1.62.33.00.41.6-1.61.6-1.61.71.51.6-1.4-1.71.7-1.5
Reaction time mean2.02.84.1-0.7-1.61.7-1.61.7-2.0-1.6-1.71.51.9-1.92.0
Reaction time mean AUC2.12.84.0-0.8-1.61.7-1.61.7-2.0-1.6-1.71.61.8-1.82.0
Median of all reaction times3.24.46.60.1-2.02.0-2.02.0-2.6-2.0-2.01.92.5-2.52.5
Reaction time omissions1.31.85.02.21.3-1.31.3-1.30.91.31.3-1.2-0.90.9-1.6
Reaction time false alarm rate0.40.62.81.70.7-0.70.7-0.70.50.80.7-0.7-0.40.4-0.5
Reaction time premature initiation rate0.20.30.6-0.2-0.70.6-0.60.6-0.5-0.6-0.60.80.2-0.20.5
Reaction time premature initiations0.10.20.8-0.50.2-0.20.2-0.20.60.20.2-0.0-0.90.9-0.4
Std. dev. reaction times0.50.72.7-1.7-0.80.8-0.80.8-0.7-0.7-0.80.80.4-0.40.7
Reaction time trials completed1.62.33.00.41.6-1.61.6-1.61.71.51.6-1.4-1.71.7-1.5
Reaction time trials AUC1.72.43.10.51.6-1.61.6-1.61.81.61.6-1.5-1.61.7-1.4
Run reversals in cocaine runway, females0.30.30.8-0.60.4-0.40.4-0.40.60.30.4-0.2-0.80.8-0.9
Run reversals in cocaine runway, males0.80.81.6-0.80.7-0.70.7-0.71.00.70.7-1.0-1.31.3-1.0
Latency to leave start box in cocaine runway0.10.10.20.50.2-0.20.2-0.20.20.30.2-0.4-0.10.1-0.4
Latency to leave start box in cocaine runway, F0.70.71.5-0.30.9-0.90.9-0.91.00.90.8-1.2-0.80.8-0.7
Latency to leave start box in cocaine runway, M0.80.71.61.3-0.60.6-0.60.6-1.0-0.6-0.60.71.2-1.20.8
Std. dev. time between licks in bursts0.50.62.8-1.7-0.70.6-0.60.6-0.1-0.7-0.60.7-0.90.9-0.3
Total sessions with >9 infusions0.20.20.20.20.5-0.50.5-0.50.50.50.5-0.4-0.40.4-0.3
Short access day 1 total inactive lever presses0.60.61.21.10.9-0.90.9-0.90.70.90.9-0.8-0.40.5-0.3
Short access day 10 total inactive lever presses3.74.15.41.92.2-2.22.2-2.21.92.22.2-2.3-1.61.6-1.7
Short access day 1 total infusions2.22.42.90.81.7-1.71.7-1.71.61.71.7-1.7-1.41.4-1.3
Short access day 10 total infusions0.30.30.7-0.3-0.50.5-0.50.5-0.5-0.5-0.50.50.5-0.60.9
Short access total infusions0.10.10.1-0.00.3-0.30.3-0.30.30.30.3-0.3-0.20.20.1
Short access day 1 locomotion0.70.81.0-0.10.9-0.90.9-0.91.00.90.9-0.9-1.01.0-0.9
Short access day 10 total locomotion0.10.10.2-0.1-0.30.3-0.30.3-0.4-0.2-0.30.10.3-0.30.3
Short access total locomotion0.10.10.3-0.5-0.30.3-0.30.3-0.2-0.2-0.30.10.1-0.10.4
One hour access (0.3 mA shock)0.30.40.60.70.7-0.70.7-0.70.60.70.7-0.8-0.50.5-0.4
Compulsive drug intake0.40.40.80.10.6-0.60.6-0.60.60.70.6-0.8-0.70.7-0.9
One hour access (shock baseline)0.60.71.30.5-0.80.8-0.80.8-0.9-0.8-0.80.90.9-0.91.1
Social response proportion0.20.21.00.9-0.10.1-0.10.10.1-0.1-0.10.3-0.70.7-1.0
Social responses0.20.21.00.5-0.10.0-0.00.00.1-0.0-0.00.3-0.70.7-1.0
Social time8.010.515.62.13.2-3.23.2-3.23.43.33.3-3.2-3.33.3-4.0
Soleus weight1.33.97.92.82.1-2.12.1-2.11.82.12.1-1.9-1.11.1-1.7
Bone: stiffness0.61.01.80.41.2-1.21.2-1.21.31.21.2-1.2-0.10.1-0.4
Tibialis anterior weight1.03.412.03.51.9-1.91.9-1.91.71.81.9-1.7-0.60.7-1.3
Time to tail flick, vehicle, before self-admin2.22.32.80.81.6-1.61.6-1.61.51.71.6-1.7-1.41.4-1.4
Time to tail flick, vehicle, after self-admin1.41.52.50.61.2-1.21.2-1.21.21.21.2-1.2-1.41.4-1.6
Time to tail flick, test, before self-admin0.60.61.00.80.7-0.70.7-0.70.70.80.7-0.9-0.70.7-1.0
Time to tail flick, test, after self-admin0.10.10.4-0.6-0.30.3-0.30.3-0.3-0.4-0.30.40.1-0.10.4
Delta time to tail flick, vehicle, before/after SA0.10.10.90.60.0-0.00.0-0.00.20.00.0-0.0-0.50.5-1.0
Delta time to tail flick, test, before/after SA1.21.02.2-1.5-1.01.0-1.01.0-0.8-1.1-1.01.10.6-0.61.1
Tibia length1.64.631.95.71.7-1.71.7-1.71.01.71.7-1.7-0.50.5-1.1
Ambulatory time before self-admin0.40.40.80.90.6-0.60.6-0.60.50.60.6-0.6-0.40.5-0.4
Ambulatory time after self-admin0.50.51.81.30.8-0.80.8-0.70.50.70.8-0.6-0.20.2-0.2
Bone: tissue strength0.60.62.1-1.50.5-0.50.5-0.50.90.50.5-0.5-1.01.0-0.7
Total heroin consumption0.10.10.10.3-0.30.3-0.30.3-0.3-0.3-0.30.3-0.00.00.2
Bone: trabecular number0.81.24.62.1-0.30.3-0.30.4-0.7-0.4-0.40.41.9-1.81.2
Bone: trabecular spacing0.10.10.5-0.70.2-0.20.2-0.20.40.10.2-0.2-0.60.6-0.4
Bone: trabecular thickness1.01.26.42.5-0.40.4-0.40.4-0.9-0.4-0.40.51.6-1.51.1
Bone: trabecular tissue density0.71.01.40.51.2-1.21.2-1.11.11.21.2-1.2-0.40.4-0.9
Water consumed over 24 hours1.01.11.8-1.2-1.01.0-1.01.0-0.8-1.1-1.11.01.0-1.01.4
Number of responses in last shaping day0.70.71.0-0.10.8-0.80.8-0.81.00.80.8-0.7-1.01.0-0.8