Fkbpl

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Fkbpl 0.1 0.06 8.5e-05 0.04 0.06 0.1 0.08 5.6e-03 3.2e-04 9.7e-06 3.6e-05
2 NAcc gene expression Fkbpl 0.37 0.1 0.0e+00 0.35 0.41 0.4 0.42 1.0e-54 2.0e-66 5.8e-65 4.8e-69
3 Brain mRNA stability Fkbpl 0.14 0.12 1.5e-06 0.06 0.07 0.04 0.06 1.8e-06 9.3e-07 7.0e-05 1.0e-06
4 PL gene expression Fkbpl 0.58 0.1 0.0e+00 0.55 0.49 0.6 0.6 1.3e-72 1.3e-60 1.5e-81 3.9e-82
5 IL gene expression Fkbpl 0.58 0.14 6.3e-12 0.38 0.36 0.39 0.38 5.2e-10 1.9e-09 2.0e-10 5.2e-10
6 pVTA gene expression Fkbpl 0.45 0.12 0.0e+00 0.27 0.34 0.35 0.34 5.0e-22 4.7e-28 9.1e-29 4.3e-28
7 NAcc mRNA stability Fkbpl 0.04 0.02 7.0e-06 0.03 0.04 0.04 0.04 7.8e-06 2.6e-06 3.8e-06 5.9e-07
8 PL mRNA stability Fkbpl 0.13 0.06 3.0e-12 0.12 0.08 0.11 0.12 2.0e-13 2.0e-09 2.4e-12 2.1e-13
9 OFC gene expression Fkbpl 0.59 0.13 4.1e-12 0.42 0.36 0.44 0.42 3.1e-11 1.8e-09 9.0e-12 3.9e-11
10 BLA gene expression Fkbpl 0.56 0.12 0.0e+00 0.4 0.46 0.41 0.45 7.4e-23 5.4e-27 3.3e-23 2.0e-26
11 IC gene expression Fkbpl 0.7 0.1 0.0e+00 0.52 0.53 0.53 0.53 7.7e-25 1.5e-25 1.5e-25 1.7e-25
12 Brain gene expression Fkbpl 0.52 0.12 0.0e+00 0.38 0.41 0.43 0.43 2.4e-37 1.5e-40 1.1e-43 7.1e-44
13 LHb gene expression Fkbpl 0.27 0.13 7.3e-04 0.06 0.11 0.09 0.06 1.5e-02 1.6e-03 4.9e-03 1.3e-02
14 Adipose gene expression Fkbpl 0.13 0.05 2.2e-13 0.12 0.09 0.08 0.03 4.2e-13 6.9e-10 3.0e-09 1.4e-04
15 pVTA mRNA stability Fkbpl 0.06 0.03 4.3e-04 0.03 0.02 0.01 0.02 1.0e-03 5.6e-03 2.3e-02 1.0e-02
16 Liver gene expression Fkbpl 0.4 0.12 0.0e+00 0.25 0.27 0.3 0.3 1.0e-27 5.7e-30 2.7e-34 2.0e-33
17 IC intron excision ratio chr20_4102943_4103288 0.19 0.1 3.3e-04 0.03 0.02 0.02 0.02 1.6e-02 5.5e-02 4.6e-02 3.6e-02
18 IC intron excision ratio chr20_4105615_4105815 0.19 0.1 1.5e-04 0.03 0.03 0.02 0.02 1.8e-02 2.4e-02 6.5e-02 4.6e-02
19 RMTg gene expression Fkbpl 0.16 0.09 2.3e-03 0.12 0.07 0.1 0.07 5.8e-04 5.7e-03 1.7e-03 5.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.30.63.9-0.81.2-0.40.3-0.71.00.2-1.10.10.3-0.10.60.20.5-0.32.00.6-0.60.4
Area under the delay curve0.30.31.40.4-0.40.1-0.20.1-0.8-0.90.7-0.0-0.2-0.1-0.7-0.3-1.00.2-1.20.7-0.70.2
BMI with tail2.58.511.32.73.12.83.32.62.53.02.33.23.13.33.03.23.43.32.1-3.33.30.4
BMI without tail2.06.29.32.82.12.92.43.12.13.02.92.82.32.72.52.52.62.5-0.6-2.62.60.8
Body weight2.19.117.54.22.13.13.03.51.23.13.43.32.73.42.53.03.33.4-0.6-3.93.9-1.0
Weight adjusted by age0.61.04.32.1-0.00.70.51.3-0.20.71.20.70.20.70.40.80.90.9-1.0-1.51.5-0.9
Bone surface0.00.10.3-0.00.1-0.4-0.0-0.3-0.40.1-0.20.2-0.3-0.20.1-0.30.3-0.30.10.2-0.2-0.6
Bone volume0.10.20.80.20.90.10.40.10.40.6-0.10.60.30.20.70.30.90.20.80.2-0.2-0.2
Breakpoint value in progressive ratio session0.30.31.4-1.2-0.4-0.6-0.5-0.7-0.4-0.7-0.6-0.6-0.6-0.5-0.7-0.6-0.6-0.3-0.20.2-0.2-0.5
Number of licking bursts1.21.93.6-0.9-1.5-1.4-1.4-1.3-1.9-1.4-1.0-1.2-1.5-1.3-1.6-1.5-1.4-1.3-0.91.5-1.5-1.3
Context. condit. distance diff. score5.36.510.8-2.8-2.6-3.3-2.7-3.1-2.4-2.6-3.2-3.0-2.7-2.8-2.6-2.5-1.9-2.50.41.4-1.4-2.4
Locomotion velocity, session 12.62.84.2-1.6-1.7-1.7-1.9-1.5-1.4-1.5-1.5-1.8-1.9-1.9-1.5-1.8-1.7-2.0-1.11.9-1.90.1
Locomotion distance, session 10.40.51.7-1.30.2-0.6-0.3-1.00.3-0.4-1.0-0.6-0.2-0.5-0.1-0.3-0.4-0.71.20.8-0.80.7
Locomotion velocity, session 20.91.01.7-1.3-1.2-0.9-1.1-1.1-0.8-1.2-0.9-1.2-0.9-1.0-1.2-1.0-1.3-0.9-0.40.9-0.9-0.2
Locomotion distance, session 20.50.72.2-1.5-0.4-1.0-0.4-1.4-0.2-1.2-1.4-0.9-0.3-0.6-0.8-0.4-0.8-0.31.40.4-0.4-0.5
Locomotion velocity, session 30.20.21.1-0.00.30.60.10.50.70.50.50.10.40.30.50.30.20.1-0.30.5-0.51.1
Locomotion distance, session 30.91.02.9-1.7-0.7-1.0-0.9-1.30.1-1.1-1.3-1.3-0.6-1.0-0.9-0.8-1.1-0.90.60.9-0.90.1
Stereotopy head waving bouts, day 30.30.32.10.7-0.70.0-0.20.3-1.2-0.20.70.1-0.4-0.0-0.3-0.3-0.2-0.1-1.50.1-0.1-0.4
Stereotopy head waving duration, day 30.30.43.50.9-0.60.2-0.30.7-0.90.20.80.1-0.40.0-0.0-0.2-0.1-0.3-1.90.4-0.40.3
Locomotion velocity, session 71.92.15.0-2.2-0.6-1.7-0.9-2.2-0.2-1.9-2.2-1.6-0.7-1.2-1.4-0.9-1.3-0.92.10.6-0.6-1.1
Locomotion distance, session 72.63.26.9-2.6-1.0-2.1-1.6-2.5-0.3-2.1-2.6-2.2-1.3-1.9-1.7-1.5-1.8-1.71.41.6-1.6-0.8
Stereotopy head waving bouts, day 70.70.84.9-0.0-0.80.1-0.70.2-0.4-0.20.5-0.4-0.6-0.6-0.4-0.8-0.9-0.9-2.21.4-1.41.3
Stereotopy head waving duration, day 70.30.43.00.4-0.30.5-0.10.6-0.10.20.80.1-0.10.00.1-0.2-0.3-0.3-1.70.6-0.61.3
Locomotion velocity, session 84.75.69.3-2.1-3.1-2.6-2.7-2.4-2.9-2.6-2.1-2.7-2.7-2.5-2.8-2.6-2.4-2.0-1.61.4-1.4-1.9
Locomotion distance, session 84.05.812.0-3.0-2.0-3.2-2.2-3.4-2.0-2.7-3.5-2.7-2.2-2.4-2.4-2.1-1.7-1.91.61.1-1.1-2.6
Degree of sensitization distance0.70.72.2-0.4-0.9-1.0-0.8-0.8-1.2-1.0-0.8-0.7-0.9-0.8-1.0-0.8-0.6-0.5-0.30.3-0.3-1.5
Degree of sensitization stereotypy0.80.82.3-0.7-0.8-0.2-0.9-0.3-0.2-0.4-0.1-0.7-0.7-0.8-0.5-0.9-1.0-1.2-1.51.4-1.41.4
Conditioned locomotion0.50.51.31.00.50.40.80.6-0.20.50.60.80.50.70.40.60.80.90.4-1.21.2-1.0
Cocaine response after cond. corrected0.50.64.00.00.5-0.40.5-0.6-0.1-0.3-0.60.10.40.3-0.20.30.50.81.8-0.50.5-2.0
Cocaine response after cond. not corrected0.20.32.90.2-0.3-0.20.0-0.2-0.7-0.3-0.00.0-0.10.1-0.4-0.10.20.40.1-0.60.6-1.7
Cocaine response before conditioning0.91.010.30.8-1.00.8-0.51.2-0.70.51.50.3-0.40.10.1-0.3-0.2-0.2-3.2-0.70.71.0
Saline control response4.15.510.12.82.23.02.23.22.32.82.82.62.42.42.52.32.02.1-0.7-1.21.22.4
Bone: connectivity density0.30.54.3-0.51.0-0.50.4-0.70.60.2-1.10.20.2-0.00.50.20.6-0.22.1-0.10.1-0.1
Bone: cortical apparent density2.73.75.02.02.22.12.21.82.01.92.02.12.22.02.12.12.12.01.1-1.51.51.0
Bone: cortical area0.10.10.50.10.10.20.20.2-0.10.10.50.40.00.20.10.00.10.1-0.3-0.70.70.3
Bone: cortical porosity2.32.58.2-1.0-1.5-0.5-1.7-0.4-1.0-1.10.0-1.1-1.5-1.4-1.0-1.5-1.9-1.8-2.92.4-2.41.9
Bone: cortical porosity2.93.28.7-1.1-1.8-0.9-1.9-0.7-1.5-1.4-0.3-1.3-1.8-1.7-1.4-1.8-2.2-2.1-3.02.5-2.51.6
Bone: cortical thickness1.42.34.01.01.91.71.71.31.91.41.51.71.71.51.81.51.31.30.8-1.31.32.0
Bone: cortical thickness3.23.86.71.42.12.32.11.82.62.01.92.02.42.22.12.11.72.01.0-1.51.51.8
Bone: cortical tissue density2.53.44.52.02.12.02.11.71.91.81.92.02.11.92.02.02.01.91.0-1.41.40.9
Condit. Reinf. active minus inactive responses1.21.32.7-1.6-0.9-0.7-1.2-0.9-0.4-1.3-1.0-1.1-0.9-1.0-1.0-1.0-1.7-1.4-0.91.4-1.41.1
Condit. Reinf. active-inactive response ratio0.30.32.4-0.10.30.70.30.40.60.20.60.40.40.40.30.3-0.3-0.0-0.60.1-0.11.5
Condit. Reinf. active responses0.60.72.5-1.6-0.5-0.6-0.7-0.90.2-1.2-1.2-0.9-0.5-0.7-0.8-0.6-1.2-0.80.20.7-0.70.6
Condit. Reinf. inactive responses0.40.52.8-1.40.4-0.5-0.1-0.90.9-0.6-1.3-0.60.2-0.3-0.2-0.0-0.4-0.11.7-0.10.1-0.0
Incentive salience index mean2.53.16.1-2.5-1.6-1.9-1.8-2.1-1.4-2.4-2.1-1.8-1.7-1.7-2.0-1.8-2.1-1.7-0.11.1-1.1-0.6
Condit. Reinf. lever presses3.24.49.2-2.7-1.6-2.7-1.9-2.9-2.0-2.7-3.0-2.1-2.0-2.0-2.3-2.0-1.7-1.61.10.4-0.4-2.5
Condit. Reinf. active minus inactive responses0.20.22.20.2-0.50.3-0.30.6-0.20.30.5-0.0-0.3-0.00.1-0.10.1-0.0-1.5-0.30.30.2
Condit. Reinf. active-inactive response ratio0.30.43.20.2-1.0-0.1-0.70.4-0.9-0.00.2-0.3-0.7-0.3-0.3-0.5-0.1-0.3-1.8-0.10.1-0.2
Condit. Reinf. active responses0.10.10.6-0.0-0.20.2-0.30.40.10.30.1-0.1-0.2-0.10.2-0.00.1-0.1-0.8-0.10.10.5
Condit. Reinf. inactive responses0.30.41.10.30.80.80.70.51.00.70.60.60.80.70.70.70.50.60.5-0.30.30.9
Condit. Reinf. lever presses0.40.61.5-0.9-0.6-0.6-1.0-0.5-0.2-0.4-0.8-0.8-0.9-1.0-0.4-0.8-0.8-1.2-0.70.8-0.80.9
Condit. Reinf. lever reinforcers received0.10.21.1-0.3-0.6-0.0-0.60.1-0.10.1-0.1-0.4-0.4-0.4-0.1-0.4-0.3-0.5-1.00.2-0.20.6
Conditioned reinforcement - actives0.10.10.50.30.40.20.30.30.70.3-0.00.20.30.30.20.40.30.50.6-0.00.0-0.1
Conditioned reinforcement - inactives0.00.00.20.30.20.10.10.40.4-0.00.00.10.00.1-0.00.2-0.20.3-0.00.2-0.20.1
Conditioned locomotion0.10.10.30.1-0.3-0.3-0.4-0.1-0.0-0.4-0.4-0.4-0.4-0.4-0.4-0.2-0.3-0.3-0.0-0.10.1-0.6
Patch foraging indifference point 0 sec1.73.15.62.31.82.41.82.21.71.92.31.91.92.01.61.91.52.0-0.5-0.60.60.7
Patch foraging indifference point AUC0.20.21.7-0.1-0.50.1-0.50.1-0.3-0.40.4-0.3-0.4-0.3-0.4-0.5-0.5-0.6-1.30.6-0.60.1
Delay disc. indifference point, 0s delay0.50.62.00.1-0.8-0.7-0.4-0.7-1.4-1.1-0.3-0.6-0.6-0.5-1.0-0.6-0.90.1-0.31.1-1.1-0.8
Delay disc. indifference point, 16s delay0.20.20.90.60.50.70.40.60.50.00.80.50.50.40.30.4-0.20.2-0.30.2-0.20.9
Delay disc. indifference point, 2s delay1.11.23.6-0.1-1.4-0.6-1.0-0.3-1.6-1.30.1-0.8-1.1-0.8-1.5-0.9-1.4-0.6-1.91.3-1.3-1.0
Delay disc. indifference point, 24s delay0.40.53.21.0-0.40.5-0.30.5-0.3-0.51.00.0-0.1-0.1-0.3-0.1-0.8-0.2-1.80.5-0.51.0
Delay disc. indifference point, 4s delay0.30.42.60.5-0.20.60.10.7-0.6-0.21.20.30.10.3-0.40.0-0.40.7-1.60.2-0.2-0.4
Delay disc. indifference point, 8s delay0.20.31.20.2-0.3-0.0-0.2-0.2-0.6-1.00.4-0.1-0.1-0.2-0.7-0.3-1.10.1-0.80.5-0.50.5
Indifference point function ln k0.61.12.0-1.2-1.3-1.1-1.2-1.1-1.1-1.4-0.7-1.1-1.1-1.1-1.3-1.2-1.4-1.0-0.80.5-0.5-0.3
Indifference point function log k0.61.12.0-1.2-1.3-1.1-1.2-1.1-1.1-1.4-0.7-1.1-1.1-1.1-1.3-1.2-1.4-1.0-0.80.5-0.5-0.3
Patch foraging total patch changes 0 sec1.83.45.92.31.92.41.92.31.81.92.32.02.02.01.72.01.52.0-0.4-0.70.70.9
Patch foraging total patch changes 12 sec1.62.03.71.71.51.91.41.81.51.61.91.51.51.51.41.41.31.3-0.5-0.70.70.7
Patch foraging total patch changes 18 sec3.45.28.42.02.92.62.72.12.72.42.22.52.82.62.52.52.42.31.4-0.90.91.2
Patch foraging total patch changes 24 sec0.91.53.61.11.81.41.41.01.91.20.81.21.61.21.41.41.01.01.20.1-0.11.3
Patch foraging total patch changes 6 sec1.92.95.32.31.92.21.82.11.71.82.11.81.91.81.61.81.41.7-0.1-0.40.41.0
Patch foraging time to switch 0 sec1.53.26.41.22.01.12.01.01.41.80.71.71.91.91.92.02.12.12.5-2.12.10.1
Patch foraging water rate 0 sec0.10.10.90.90.10.40.30.50.0-0.10.60.40.20.3-0.10.2-0.00.3-0.6-0.10.1-0.5
Patch foraging water rate 12 sec0.20.30.90.20.90.50.60.30.70.40.30.50.70.40.60.50.40.20.70.8-0.80.5
Patch foraging water rate 18 sec0.30.41.51.20.70.90.70.80.50.50.80.70.80.80.40.70.30.8-0.1-0.00.00.0
Patch foraging water rate 24 sec0.30.40.90.70.90.70.80.70.70.80.50.80.80.80.70.70.70.70.3-0.20.20.4
Patch foraging water rate 6 sec0.20.30.60.40.80.70.70.50.70.30.70.70.80.70.40.60.40.70.5-0.00.00.0
Seeking ratio, delayed vs. immediate footshock0.91.13.50.50.31.40.61.21.01.11.90.70.80.80.70.50.51.1-1.6-1.51.51.0
Distance traveled before self-admin0.40.61.60.20.50.20.7-0.10.20.70.00.60.50.60.50.51.20.91.1-1.31.3-1.3
Distance traveled after self-admin0.70.81.71.00.41.00.71.10.31.21.30.90.70.90.70.71.10.6-0.8-1.21.2-0.2
Extensor digitorum longus weight0.10.53.7-0.2-0.7-0.8-0.5-0.4-1.0-0.4-0.8-0.4-0.8-0.4-0.7-0.5-0.1-0.1-0.2-0.40.4-1.9
Bone: elastic displacement0.30.31.60.00.10.4-0.10.20.40.00.3-0.10.2-0.1-0.00.1-0.5-0.2-0.61.3-1.31.1
Bone: elastic work0.10.10.30.40.20.50.30.40.20.00.60.40.30.30.10.3-0.10.3-0.50.1-0.10.3
Bone: endosteal estimation0.71.67.11.0-1.9-0.5-0.80.5-2.4-0.20.5-0.3-1.3-0.3-1.1-0.8-0.1-0.0-2.6-0.80.8-2.7
Bone: endosteal perimeter1.02.16.7-0.5-2.0-1.6-1.3-1.0-2.6-1.3-0.7-1.0-1.8-1.1-1.7-1.5-0.9-0.9-1.3-0.30.3-2.5
Epididymis fat weight8.629.343.14.26.65.46.34.86.25.54.25.66.36.06.06.15.85.74.5-4.84.82.6
Delta time in closed arm before/after self-admin0.20.21.01.00.30.10.50.4-0.50.50.30.50.20.50.40.50.60.40.6-0.10.1-0.2
Delta time in open arm before/after self-admin0.10.10.4-0.40.20.30.00.40.50.50.1-0.00.20.20.40.30.20.2-0.2-0.10.10.6
Diff in mean of infusions in LGA sessions0.70.93.0-1.5-0.3-1.2-0.4-1.6-0.3-1.1-1.5-0.7-0.5-0.7-0.8-0.8-0.8-0.61.70.1-0.1-0.5
Delay discount exponential model param0.40.42.0-0.30.5-0.10.3-0.10.80.9-0.80.10.20.20.70.31.1-0.11.4-0.80.8-0.2
Extinction: sum of active levers before priming0.80.91.5-1.0-1.0-1.1-0.8-1.0-1.2-1.2-1.0-0.9-1.0-0.9-1.2-0.9-1.0-0.8-0.00.6-0.6-1.2
Active lever presses in extinction session 60.10.10.4-0.30.4-0.00.2-0.00.3-0.3-0.30.10.10.10.10.2-0.2-0.10.60.3-0.30.6
Bone: final force2.64.16.02.21.82.12.22.11.62.01.92.22.12.41.82.12.12.50.6-2.42.40.1
Bone: final moment1.83.04.22.01.51.81.91.91.31.81.61.91.82.01.61.81.82.00.5-1.91.90.1
Food consumed during 24 hour testing period0.40.52.80.70.20.10.60.3-0.40.20.30.50.40.60.00.50.61.00.6-1.31.3-1.7
Glucose5.58.615.7-1.9-3.6-3.3-3.3-2.6-4.0-3.0-2.6-2.9-3.5-3.0-3.3-3.1-2.7-2.8-2.02.1-2.1-2.7
Heart weight0.40.65.11.3-0.50.6-0.31.2-0.70.31.20.4-0.20.20.10.1-0.2-0.0-2.3-0.10.10.8
Delay discount hyperbolic model param0.50.52.7-0.20.6-0.10.4-0.10.91.0-0.70.20.40.20.80.41.2-0.11.6-0.90.9-0.2
Intermittent access intake day 1-15 change0.10.10.40.30.00.40.10.30.30.50.40.20.20.10.3-0.00.20.0-0.40.5-0.50.7
Intermittent access intake escalation0.30.62.30.70.61.10.60.91.01.01.00.60.80.60.80.50.40.4-0.50.4-0.41.5
Intermittent access intake escalation 20.20.20.90.0-0.5-0.1-0.4-0.1-0.3-0.1-0.0-0.4-0.3-0.4-0.3-0.5-0.5-0.6-0.70.9-0.90.4
Intermitt. access day 1 inactive lever presses0.20.94.80.1-1.0-1.2-0.7-0.8-1.7-0.8-0.9-0.7-1.0-0.7-1.1-0.8-0.3-0.20.10.4-0.4-2.2
Intermitt. access day 15 inactive lever presses0.10.10.30.60.10.30.20.5-0.00.30.40.40.10.30.10.30.20.5-0.3-0.50.5-0.4
Intermitt. access escalation Index0.81.24.6-2.2-0.5-1.4-0.6-1.7-0.7-1.4-1.4-1.0-0.8-0.9-1.0-1.0-0.8-0.71.0-0.10.1-0.9
Intermittent access day 1 total infusions0.81.32.7-1.1-0.7-1.3-1.2-1.1-0.0-1.2-1.6-1.4-1.1-1.2-1.1-0.9-1.3-1.20.41.7-1.7-0.2
Intermittent access day 15 total infusions0.20.21.3-0.10.20.1-0.20.10.80.0-0.2-0.30.0-0.20.0-0.1-0.4-0.3-0.11.1-1.10.9
Intermittent access terminal intake (last 3 days)0.20.21.00.1-0.10.1-0.40.20.50.0-0.1-0.3-0.2-0.3-0.1-0.1-0.5-0.5-0.61.0-1.00.8
Intermittent access total infusions0.30.31.6-0.2-0.1-0.3-0.6-0.10.4-0.3-0.5-0.6-0.4-0.5-0.3-0.2-0.6-0.6-0.21.3-1.30.5
Intermittent access day 1 locomotion0.10.10.70.20.40.00.20.10.80.2-0.3-0.10.20.10.30.30.40.30.7-0.10.1-0.1
Intermittent access day 15 total locomotion0.50.91.81.30.71.00.91.01.01.01.00.90.90.90.90.81.01.0-0.1-1.41.40.0
Intermittent access total locomotion0.40.41.11.10.70.70.60.81.00.70.60.50.60.60.70.70.60.70.2-0.40.40.4
Intermittent access standard deviation1.32.87.22.71.51.91.62.21.42.02.01.71.61.81.71.71.71.9-0.1-0.40.40.8
Left kidney weight2.19.915.13.92.73.53.13.81.93.43.73.63.03.53.13.23.33.2-0.5-3.53.50.7
Right kidney weight2.210.116.94.12.83.33.33.61.63.33.53.83.03.63.13.23.53.50.3-3.63.60.3
Cocaine induced anxiety0.10.21.7-0.6-0.1-0.40.0-0.5-0.4-0.5-0.4-0.2-0.2-0.1-0.4-0.2-0.00.40.4-0.40.4-1.3
Post-drug Anxiety0.20.20.90.30.10.10.30.2-0.20.20.30.30.20.3-0.00.20.30.90.1-0.80.8-0.9
Baseline Anxiety0.10.10.70.80.10.40.20.50.00.50.50.40.20.30.20.20.10.4-0.3-0.20.20.2
Tail length0.51.918.01.6-1.60.5-0.71.3-1.60.21.70.2-0.9-0.1-0.8-0.6-0.4-0.3-4.2-0.50.5-1.4
Length with tail0.52.311.72.5-1.00.90.11.8-1.70.62.10.8-0.20.7-0.40.30.50.7-3.4-1.61.6-2.3
Length without tail1.34.29.83.00.91.41.82.0-0.51.42.02.11.42.21.01.92.32.5-0.0-3.13.1-2.7
Times rat made contact with spout0.60.74.8-0.50.60.70.20.21.40.10.40.00.60.20.40.2-0.4-0.1-0.01.5-1.52.2
Lifetime Intake0.20.31.6-0.0-0.1-0.2-0.5-0.00.3-0.4-0.4-0.5-0.3-0.4-0.3-0.2-0.6-0.4-0.31.2-1.20.3
Liver weight, left0.30.63.90.5-1.1-0.4-0.40.0-1.5-0.00.1-0.2-0.6-0.1-0.5-0.40.40.2-0.9-0.80.8-2.0
Liver weight, right0.91.56.7-0.1-1.9-1.0-1.2-0.5-2.0-1.1-0.4-0.9-1.3-0.8-1.6-1.0-0.8-0.3-1.6-0.20.2-2.6
Locomotor activity0.20.43.70.4-0.80.3-0.40.5-0.70.11.0-0.1-0.3-0.0-0.5-0.3-0.4-0.1-1.9-0.10.1-0.3
Locomotor testing distance0.10.20.80.2-0.70.1-0.30.2-0.60.00.5-0.3-0.20.1-0.4-0.1-0.20.1-0.9-0.70.7-0.9
Locomotor testing rearing0.20.52.21.0-0.10.40.30.7-0.20.60.50.30.30.60.10.50.70.6-0.3-1.11.1-1.5
Locomotion in novel chamber0.10.10.30.40.30.40.40.50.10.50.30.20.40.40.30.40.30.50.2-0.10.10.1
Locomotion in novel chamber post-restriction1.01.72.71.31.21.41.41.50.91.41.41.51.31.31.31.41.51.10.3-1.61.60.2
Fecal boli incidents, locomotor time 10.20.22.4-0.40.3-0.5-0.1-0.10.00.1-0.9-0.2-0.2-0.10.40.30.6-0.11.5-0.10.1-0.5
Change in fecal boli incidents, locomotor task0.50.51.80.7-0.9-0.1-0.3-0.2-1.1-0.50.4-0.1-0.4-0.3-1.0-0.5-0.60.1-1.4-0.50.5-1.3
Time >=10cm from walls, locomotor time 11.41.54.21.30.50.61.10.8-0.50.81.01.20.71.20.60.91.51.60.6-2.12.1-1.9
Bouts of movement, locomotor time 10.20.20.7-0.8-0.2-0.4-0.3-0.7-0.1-0.6-0.4-0.4-0.3-0.5-0.2-0.6-0.4-0.5-0.0-0.00.00.5
Total resting periods, locomotor time 10.20.20.7-0.8-0.3-0.5-0.5-0.7-0.3-0.6-0.4-0.4-0.4-0.6-0.3-0.6-0.4-0.7-0.10.1-0.10.3
Rest time, locomotor task time 10.50.61.2-0.7-0.8-0.8-0.9-0.4-0.9-0.5-0.6-0.7-0.9-0.8-0.5-0.6-0.4-1.0-0.31.1-1.1-0.5
Distance moved, locomotor task time 10.50.71.31.10.71.00.90.80.80.51.10.80.90.90.40.70.50.9-0.4-1.11.1-0.2
Vertical activity count, locomotor time 10.82.03.01.61.41.61.71.31.11.21.71.61.61.61.11.41.01.60.1-1.71.70.5
Time >=10cm from walls, locomotor time 20.40.62.41.6-0.20.40.40.6-1.00.11.00.70.20.5-0.20.40.30.7-0.8-0.80.8-1.5
Bouts of movement, locomotor time 20.20.31.3-0.5-0.5-0.1-0.50.0-0.8-0.20.3-0.3-0.5-0.4-0.3-0.5-0.6-0.4-1.20.7-0.70.8
Total resting periods, locomotor time 20.61.02.6-0.8-1.1-0.6-1.2-0.4-1.3-0.7-0.1-0.9-1.1-1.0-0.8-1.1-1.1-0.9-1.61.2-1.20.5
Rest time, locomotor task time 20.81.02.7-0.7-1.0-1.3-0.8-1.1-1.6-0.9-1.2-0.8-1.0-0.8-0.9-0.9-0.3-0.70.40.7-0.7-1.6
Distance moved, locomotor task time 21.51.74.12.01.31.51.41.41.60.91.41.41.51.41.11.41.01.30.1-1.41.40.5
Vertical activity count, locomotor time 20.91.22.71.71.11.21.21.10.90.81.31.11.11.20.81.20.71.2-0.0-1.41.40.2
Light reinforcement 10.82.03.71.61.61.21.91.00.91.21.11.71.61.81.21.41.71.91.4-1.21.2-0.7
Light reinforcement 20.50.71.81.00.50.41.10.40.10.40.20.80.71.00.40.81.01.21.1-1.11.1-1.3
Bone: marrow area0.71.56.81.2-1.7-0.4-0.60.7-2.2-0.00.7-0.1-1.1-0.1-0.9-0.60.10.1-2.6-1.01.0-2.6
Bone: maximum diameter1.22.24.8-1.2-1.9-1.7-1.6-1.4-2.2-1.7-1.1-1.3-1.9-1.5-1.7-1.7-1.5-1.4-1.00.5-0.5-1.3
Bone: maximum force1.12.03.01.71.31.41.61.40.91.41.31.71.31.61.31.41.51.70.4-1.61.6-0.2
Bone: maximum moment0.71.22.31.51.01.01.21.20.51.11.11.40.91.21.01.11.21.20.1-1.11.1-0.3
Mean time between licks in bursts1.64.06.0-1.8-2.4-2.3-2.3-2.0-2.3-1.9-1.9-2.1-2.4-2.3-2.1-2.2-1.7-2.1-1.30.9-0.9-1.7
Mean num. licks in bursts1.42.26.00.61.81.81.41.42.41.51.21.21.71.41.81.61.11.20.7-0.60.62.4
Cd content in liver0.80.93.60.81.30.31.10.30.90.7-0.00.80.90.90.91.11.11.01.9-0.60.6-0.5
Co content in liver2.32.74.21.71.71.61.71.61.51.81.41.71.71.81.61.81.61.70.9-2.02.00.7
Cu content in liver0.40.52.4-1.00.80.60.2-0.11.6-0.20.0-0.10.80.30.30.4-0.30.20.70.9-0.91.3
Fe content in liver1.21.52.21.11.51.31.51.31.31.40.81.51.41.31.31.51.41.40.9-0.60.60.2
K content in liver0.40.41.1-1.0-0.3-0.8-0.7-1.0-0.2-0.5-1.1-0.8-0.5-0.6-0.4-0.6-0.3-0.70.70.5-0.5-0.2
Mg content in liver2.62.74.1-2.0-1.9-1.9-1.8-2.0-1.7-1.7-2.0-1.9-1.7-1.6-1.7-1.7-1.3-1.50.10.9-0.9-1.3
Mn content in liver2.62.86.9-1.3-2.2-2.0-1.5-1.9-2.4-2.2-1.6-1.7-1.7-1.4-2.0-1.6-1.3-0.9-0.20.6-0.6-2.6
Na content in liver0.10.10.5-0.50.20.40.10.10.7-0.20.40.00.30.10.1-0.0-0.10.1-0.10.4-0.40.6
Rb content in liver0.20.21.8-0.20.1-0.6-0.2-0.5-0.10.0-0.9-0.2-0.1-0.2-0.1-0.00.30.11.1-0.00.0-1.4
Se content in liver4.85.710.9-2.7-3.3-2.2-2.7-2.1-2.5-2.5-1.8-2.7-2.6-2.4-2.9-2.7-2.8-2.1-1.91.7-1.7-1.0
Sr content in liver0.20.11.21.1-0.2-0.20.10.2-0.70.00.10.3-0.30.00.00.00.20.0-0.3-0.00.0-0.5
Zn content in liver0.20.20.5-0.3-0.6-0.6-0.6-0.5-0.5-0.3-0.7-0.6-0.5-0.3-0.4-0.4-0.3-0.40.20.1-0.1-0.4
Bone: minimum diameter0.61.13.6-0.3-1.5-1.0-0.9-0.7-1.9-0.9-0.3-0.6-1.3-0.7-1.2-1.0-0.5-0.5-0.9-0.80.8-1.9
Time in familiar zone, hab. session 10.60.54.0-0.70.90.40.3-0.01.60.4-0.10.10.50.00.60.3-0.2-0.30.80.4-0.42.0
Time in novel zone, hab. session 10.40.41.81.1-0.6-0.1-0.10.5-1.40.10.40.2-0.40.2-0.1-0.10.40.3-1.10.0-0.0-1.2
Total zone transitions, hab. session 10.30.41.1-1.1-0.4-0.7-0.6-0.9-0.3-0.4-0.8-0.7-0.5-0.6-0.4-0.6-0.4-0.70.40.6-0.6-0.2
Total locomotion distance, hab. session 10.20.31.2-1.1-0.3-0.7-0.4-0.8-0.1-0.4-1.0-0.6-0.4-0.5-0.3-0.4-0.1-0.40.80.1-0.1-0.4
Locomotion velocity, hab. session 10.20.21.0-1.0-0.4-0.6-0.5-0.6-0.1-0.3-0.8-0.6-0.4-0.5-0.3-0.4-0.2-0.50.4-0.10.1-0.2
Time in familiar zone, hab. session 20.91.02.00.31.11.11.10.71.41.21.10.91.20.91.20.90.90.70.5-0.90.91.2
Time in novel zone, hab. session 20.30.41.90.6-0.4-0.3-0.40.1-0.7-0.4-0.2-0.2-0.5-0.3-0.4-0.3-0.4-0.3-0.81.4-1.4-0.1
Total zone transitions, hab. session 20.20.31.8-0.10.60.10.6-0.20.40.30.00.40.50.40.30.40.60.71.3-0.40.4-0.6
Total locomotion distance, hab. session 20.30.44.1-0.80.3-0.50.2-0.90.2-0.2-0.9-0.20.2-0.0-0.00.10.40.32.00.2-0.2-0.9
Locomotion velocity, hab. session 20.50.63.5-1.3-0.1-0.9-0.2-1.3-0.1-0.6-1.2-0.6-0.2-0.4-0.4-0.3-0.0-0.11.90.3-0.3-1.1
Novel to familiar place preference ratio0.40.42.3-0.3-0.4-0.4-0.5-0.3-0.5-0.6-0.3-0.5-0.5-0.6-0.5-0.5-0.6-0.5-0.51.5-1.5-0.1
Novelty place preference0.50.62.8-0.2-0.6-0.4-0.6-0.3-0.6-0.6-0.2-0.5-0.6-0.6-0.6-0.6-0.7-0.6-0.81.7-1.7-0.1
Time in novel zone, NPP test0.60.63.0-0.1-0.6-0.3-0.7-0.2-0.6-0.5-0.1-0.5-0.6-0.6-0.6-0.6-0.7-0.6-1.11.7-1.70.0
Total zone transitions, NPP test0.81.12.9-1.4-0.4-1.3-0.8-1.6-0.5-0.8-1.7-1.1-0.8-1.0-0.7-0.7-0.6-0.81.31.2-1.2-0.6
Total locomotion distance, NPP test0.60.85.0-0.80.2-1.1-0.2-1.2-0.2-0.6-1.6-0.6-0.2-0.5-0.3-0.1-0.0-0.22.20.9-0.9-0.8
Locomotion velocity, NPP test0.81.16.8-1.20.1-1.3-0.3-1.5-0.2-0.8-2.0-0.8-0.3-0.6-0.4-0.2-0.1-0.32.60.9-0.9-1.1
Intraocular pressure0.50.72.00.61.20.60.90.51.40.90.20.70.80.60.90.70.90.60.9-1.11.10.4
Delta distance traveled before/after self-admin0.60.76.10.8-0.40.8-0.31.2-0.00.41.30.1-0.00.1-0.00.0-0.4-0.3-2.50.4-0.41.0
Delta ambulatory time before/after self-admin0.50.65.60.8-0.60.6-0.40.9-0.30.21.20.0-0.1-0.0-0.1-0.1-0.4-0.4-2.40.5-0.50.8
Parametrial fat weight3.27.610.12.63.02.63.22.42.62.72.23.03.13.22.63.03.02.92.4-3.03.00.0
Pavlov. Cond. lever latency7.89.813.23.53.03.53.63.33.03.43.53.43.53.63.23.43.13.31.1-2.62.61.5
Pavlov. Cond. magazine entry latency4.45.77.9-2.6-2.7-2.2-2.8-2.2-2.0-2.6-1.9-2.6-2.6-2.6-2.6-2.7-2.7-2.6-2.02.1-2.1-0.4
Pavlov. Cond. change in total contacts2.72.84.2-2.0-2.0-1.5-2.0-1.4-1.5-1.8-1.3-1.8-1.8-1.8-1.9-1.9-1.9-1.8-1.71.2-1.2-0.5
Pavlov. Cond. index score6.98.611.3-3.3-3.1-3.1-3.4-3.1-2.8-3.3-2.9-3.2-3.2-3.2-3.2-3.3-3.1-3.0-1.52.3-2.3-1.4
Pavlov. Cond. latency score7.29.112.0-3.4-3.2-3.2-3.5-3.2-2.9-3.4-3.0-3.2-3.3-3.3-3.3-3.4-3.2-3.1-1.52.4-2.4-1.5
Pavlov. Cond. lever contacts6.37.610.6-3.1-2.7-3.2-3.1-3.1-2.8-3.1-3.3-2.9-3.1-3.0-2.9-2.9-2.5-2.7-0.61.9-1.9-2.1
Pavlov. Cond. magazine entry number3.13.95.42.22.21.92.31.81.72.11.62.22.22.12.12.22.22.31.6-1.71.70.4
Pavlov. Cond. intertrial magazine entries1.51.93.81.02.01.21.61.11.81.30.41.31.61.41.51.71.31.31.9-0.70.70.8
Pavlov. Cond. lever-magazine prob. diff.6.88.411.0-3.3-3.1-3.1-3.3-3.1-2.7-3.3-2.9-3.2-3.1-3.2-3.2-3.2-3.1-3.0-1.52.2-2.2-1.4
Pavlov. Cond. response bias4.96.08.0-2.8-2.7-2.6-2.8-2.5-2.3-2.8-2.5-2.7-2.7-2.6-2.7-2.7-2.6-2.6-1.31.9-1.9-1.1
Pavlov. Cond. lever latency0.10.22.00.2-0.3-0.30.1-0.2-0.7-0.20.10.0-0.10.0-0.2-0.10.30.40.3-0.50.5-1.4
Pavlov. Cond. magazine entry latency0.50.61.0-0.4-1.0-0.9-0.9-0.7-0.7-0.7-0.8-0.8-0.9-0.9-0.8-0.8-0.8-1.0-0.51.0-1.0-0.4
Pavlov. Cond. change in total contacts0.10.21.7-0.2-0.20.2-0.40.20.20.20.1-0.1-0.3-0.30.0-0.2-0.5-0.7-1.00.4-0.41.3
Pavlov. Cond. index score0.20.30.8-0.4-0.5-0.3-0.6-0.3-0.2-0.3-0.4-0.5-0.6-0.6-0.4-0.5-0.7-0.9-0.70.9-0.90.7
Pavlov. Cond. latency score0.10.20.6-0.2-0.4-0.1-0.5-0.10.0-0.1-0.2-0.3-0.4-0.4-0.2-0.3-0.5-0.7-0.70.7-0.70.7
Pavlov. Cond. lever contacts0.10.21.6-0.10.30.40.00.20.70.3-0.00.10.20.10.30.1-0.2-0.3-0.20.4-0.41.3
Pavlov. Cond. magazine entry number0.10.10.1-0.00.30.30.20.20.10.10.40.20.30.30.20.20.20.4-0.0-0.30.30.3
Pavlov. Cond. intertrial magazine entries0.81.22.3-1.5-1.2-1.1-1.3-1.1-1.1-1.2-0.9-1.2-1.1-1.2-1.2-1.3-1.2-1.0-0.70.3-0.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.3-0.4-0.2-0.5-0.2-0.1-0.2-0.3-0.3-0.5-0.5-0.3-0.4-0.6-0.7-0.60.7-0.70.6
Pavlov. Cond. response bias0.20.30.6-0.6-0.4-0.4-0.6-0.40.0-0.5-0.6-0.5-0.5-0.6-0.4-0.5-0.8-0.8-0.40.7-0.70.6
Time in closed arm before self-admin0.10.20.50.0-0.6-0.2-0.50.0-0.3-0.3-0.1-0.4-0.5-0.4-0.5-0.4-0.2-0.3-0.50.4-0.4-0.7
Time in closed arm after self-admin0.00.00.30.2-0.0-0.10.00.1-0.20.1-0.10.0-0.10.1-0.10.10.10.00.40.4-0.4-0.5
Time in open arm before self-admin1.31.42.8-0.8-1.2-0.9-1.3-1.0-0.5-1.1-0.8-1.3-1.2-1.3-1.2-1.3-1.5-1.7-1.21.6-1.60.3
Time in open arm after self-admin0.30.41.1-0.7-0.7-0.3-0.8-0.2-0.1-0.3-0.3-0.8-0.7-0.6-0.5-0.5-0.8-0.9-1.10.5-0.50.5
Bone: periosteal estimation0.30.73.41.0-0.90.0-0.10.7-1.40.20.80.3-0.60.1-0.4-0.30.20.2-1.8-1.11.1-1.5
Bone: periosteal perimeter0.40.72.3-0.3-1.3-0.7-0.8-0.5-1.5-0.9-0.1-0.4-1.0-0.6-1.0-0.9-0.8-0.6-1.3-0.50.5-0.9
Bone: post-yield work0.40.63.10.0-0.7-1.1-0.6-0.6-1.6-0.4-0.7-0.3-1.0-0.6-0.7-0.7-0.1-0.4-0.1-0.30.3-1.8
Progressive ratio test 1 active lever presses0.20.30.80.2-0.3-0.5-0.5-0.30.0-0.5-0.6-0.6-0.5-0.5-0.6-0.3-0.5-0.2-0.20.9-0.9-0.8
Progressive ratio test 1 breakpoint0.20.30.90.2-0.4-0.5-0.6-0.3-0.0-0.5-0.6-0.6-0.5-0.5-0.6-0.3-0.5-0.3-0.21.0-1.0-0.8
Progressive ratio test 1 inactive lever presses0.60.82.51.01.20.51.00.51.10.80.20.80.90.91.00.91.01.21.6-0.60.60.1
Progressive ratio test 2 active lever presses0.10.20.5-0.50.1-0.3-0.3-0.40.4-0.3-0.6-0.5-0.1-0.3-0.3-0.2-0.4-0.40.50.7-0.70.1
Progressive ratio test 2 breakpoint0.20.20.5-0.50.1-0.3-0.3-0.40.5-0.3-0.6-0.5-0.1-0.3-0.2-0.2-0.4-0.50.50.7-0.70.3
Progressive ratio test 2 inactive lever presses0.81.21.9-0.5-1.1-1.3-1.2-1.0-0.9-1.1-1.4-1.2-1.2-1.1-1.3-0.9-1.2-1.1-0.11.4-1.4-0.9
Incentive Sensitization - Responses0.20.31.5-1.2-0.3-0.5-0.6-0.60.1-0.5-0.6-0.7-0.4-0.6-0.4-0.6-0.6-0.90.20.5-0.50.3
Incentive Sensitization - Breakpoint0.20.21.3-1.1-0.1-0.4-0.4-0.60.3-0.3-0.6-0.5-0.2-0.4-0.2-0.5-0.4-0.80.50.4-0.40.5
Sum of active levers in priming session hrs 5-60.80.71.2-0.8-1.1-0.8-1.1-0.6-0.8-0.9-0.7-0.9-1.1-1.0-0.8-0.9-0.9-1.1-0.90.5-0.5-0.1
Progressive ratio4.26.610.12.62.33.12.73.02.03.03.22.82.62.92.52.52.62.9-0.4-2.42.40.9
Food seeking constrained by brief footshock0.10.10.40.60.10.40.00.50.50.10.10.10.20.10.10.2-0.2-0.0-0.30.2-0.20.6
Seeking ratio, punishment vs. effort3.55.16.7-1.9-2.2-2.5-2.5-2.4-1.8-2.6-2.5-2.5-2.3-2.6-2.3-2.3-2.6-2.6-0.42.3-2.3-0.5
Retroperitoneal fat weight0.31.22.80.81.20.71.30.71.10.80.41.01.31.31.01.31.31.21.7-1.31.3-0.2
Reaction time number correct1.63.25.72.42.01.91.82.01.92.01.82.11.71.72.21.81.81.30.4-0.90.91.8
Reaction time mean minus median1.33.35.5-2.4-1.7-2.1-2.0-2.1-1.7-2.0-2.0-2.0-2.0-2.0-2.0-2.0-1.8-1.9-0.61.1-1.1-1.4
Reaction time mean minus median AUC1.64.16.5-2.6-1.8-2.5-2.3-2.4-1.8-2.3-2.4-2.2-2.2-2.3-2.2-2.1-2.0-2.2-0.41.2-1.2-1.3
Reaction time num false alarms0.30.51.1-0.4-1.0-0.6-0.6-0.6-0.8-0.8-0.3-0.7-0.7-0.7-0.9-0.9-0.7-0.4-1.0-0.20.2-0.8
Reaction time num false alarms AUC0.40.62.1-0.5-1.2-0.5-0.7-0.5-0.9-0.80.0-0.7-0.8-0.7-0.9-1.0-0.8-0.5-1.5-0.20.2-0.4
Reaction time trials correct on left1.63.25.72.42.01.91.82.01.92.01.82.11.71.72.21.81.81.30.4-0.90.91.8
Reaction time trials on left1.63.05.62.42.01.81.82.01.81.91.82.01.61.72.11.71.81.30.4-0.80.81.7
Reaction time mean2.33.75.9-1.9-1.8-2.4-1.9-2.3-2.3-2.2-2.2-2.0-1.9-1.9-2.3-1.8-1.8-1.6-0.00.9-0.9-2.3
Reaction time mean AUC2.23.55.5-1.9-1.8-2.3-1.8-2.3-2.2-2.2-2.2-2.0-1.9-1.9-2.3-1.7-1.8-1.60.00.9-0.9-2.3
Median of all reaction times1.62.24.6-1.3-1.4-1.9-1.4-1.8-1.9-1.7-1.8-1.6-1.4-1.4-1.8-1.3-1.3-1.10.30.5-0.5-2.1
Reaction time omissions1.31.94.6-1.3-1.3-1.8-1.2-1.6-1.7-1.4-1.6-1.4-1.4-1.3-1.6-1.3-1.1-1.20.10.6-0.6-2.1
Reaction time false alarm rate2.23.05.4-1.8-2.3-1.6-1.9-1.6-2.0-2.0-1.1-1.9-1.8-1.8-2.2-2.1-1.9-1.4-1.70.5-0.5-1.3
Reaction time premature initiation rate0.20.20.80.90.20.30.40.7-0.10.60.40.30.30.50.40.50.70.30.2-0.40.4-0.6
Reaction time premature initiations1.22.15.12.31.41.51.61.91.01.71.51.61.31.61.71.61.71.20.3-1.01.00.4
Std. dev. reaction times2.85.27.3-2.5-2.5-2.5-2.6-2.4-2.5-2.5-2.1-2.5-2.5-2.5-2.7-2.4-2.4-2.2-1.41.4-1.4-1.8
Reaction time trials completed1.63.05.62.42.01.81.82.01.81.91.82.01.61.72.11.71.81.30.4-0.80.81.7
Reaction time trials AUC1.63.05.52.42.01.81.81.91.81.91.82.11.71.72.11.81.81.30.5-0.90.91.6
Run reversals in cocaine runway, females0.50.50.91.00.90.60.80.60.60.80.40.60.80.70.90.80.81.00.70.2-0.20.5
Run reversals in cocaine runway, males1.21.23.2-0.4-1.1-1.2-1.1-1.0-1.3-0.8-1.1-1.1-1.1-1.1-1.0-1.0-0.7-1.0-0.41.8-1.8-1.1
Latency to leave start box in cocaine runway1.11.32.8-1.5-0.9-1.4-0.9-1.4-1.2-1.5-1.3-1.0-1.1-1.0-1.4-1.0-1.0-1.00.2-0.10.1-1.7
Latency to leave start box in cocaine runway, F0.91.02.1-1.4-0.7-1.3-0.9-1.3-0.9-1.3-1.3-1.0-1.0-1.0-1.2-0.9-0.8-0.50.5-0.40.4-1.5
Latency to leave start box in cocaine runway, M0.10.10.6-0.5-0.2-0.3-0.0-0.3-0.5-0.4-0.3-0.0-0.2-0.1-0.5-0.2-0.2-0.5-0.1-0.10.1-0.8
Std. dev. time between licks in bursts2.73.66.8-1.3-2.6-2.1-2.2-1.5-2.6-1.7-1.6-1.9-2.4-2.0-2.2-2.1-1.7-1.8-1.80.3-0.3-2.1
Total sessions with >9 infusions0.30.31.30.2-0.3-0.1-0.60.10.1-0.3-0.1-0.6-0.4-0.5-0.5-0.3-0.7-0.2-1.01.2-1.20.2
Short access day 1 total inactive lever presses1.21.62.6-0.5-1.4-1.4-1.4-0.9-1.3-1.5-1.3-1.3-1.5-1.3-1.6-1.1-1.5-1.0-0.61.2-1.2-1.2
Short access day 10 total inactive lever presses0.10.21.3-0.20.0-0.50.1-0.6-0.4-0.3-0.5-0.10.0-0.0-0.2-0.20.20.31.10.1-0.1-0.8
Short access day 1 total infusions0.81.13.0-0.2-0.9-0.9-1.2-0.6-0.6-1.2-0.9-1.2-1.1-1.1-1.1-0.8-1.3-0.9-0.91.7-1.7-0.4
Short access day 10 total infusions0.10.10.4-0.30.1-0.3-0.3-0.20.5-0.2-0.5-0.4-0.2-0.3-0.2-0.1-0.3-0.10.20.6-0.60.1
Short access total infusions0.40.51.8-0.2-0.4-0.6-0.8-0.3-0.1-0.8-0.7-0.8-0.6-0.7-0.7-0.4-0.9-0.5-0.41.4-1.4-0.1
Short access day 1 locomotion0.50.61.2-0.8-0.6-1.0-0.8-1.1-0.4-0.8-1.1-1.0-0.7-0.9-0.8-0.8-0.6-0.50.30.6-0.6-0.9
Short access day 10 total locomotion0.30.62.61.3-0.60.4-0.00.8-0.40.41.00.2-0.10.2-0.2-0.00.50.7-1.6-0.80.8-1.5
Short access total locomotion0.20.21.60.6-0.6-0.3-0.4-0.1-0.5-0.2-0.1-0.4-0.4-0.3-0.4-0.3-0.00.2-0.6-0.10.1-1.3
One hour access (0.3 mA shock)0.70.81.8-1.4-0.3-0.9-0.7-1.3-0.1-0.8-1.1-0.9-0.5-0.8-0.7-0.8-0.7-1.10.91.3-1.3-0.3
Compulsive drug intake1.21.45.4-1.7-0.9-1.4-0.6-1.9-1.5-1.1-1.3-0.8-0.8-0.8-1.2-1.1-0.3-0.50.9-0.10.1-2.3
One hour access (shock baseline)0.20.42.40.10.60.40.10.41.30.30.10.10.40.10.40.4-0.3-0.40.20.8-0.81.5
Social response proportion0.20.21.30.4-0.5-0.1-0.10.1-0.9-0.50.30.0-0.40.1-0.6-0.1-0.30.5-0.80.0-0.0-1.1
Social responses0.20.21.5-0.0-0.60.2-0.20.2-0.5-0.40.7-0.1-0.20.1-0.6-0.1-0.50.4-1.2-0.50.5-0.7
Social time1.72.36.8-1.6-1.8-1.7-1.3-1.8-1.9-1.7-1.3-1.5-1.4-1.3-2.0-1.5-1.2-0.8-0.20.4-0.4-2.6
Soleus weight1.33.813.7-0.4-2.8-2.1-1.7-1.5-3.7-1.8-1.3-1.5-2.3-1.6-2.3-2.0-1.2-1.0-1.60.1-0.1-3.3
Bone: stiffness1.22.03.01.31.51.41.71.21.31.41.11.61.51.61.31.51.61.70.9-1.61.6-0.2
Tibialis anterior weight0.41.22.80.41.31.31.21.01.71.10.80.91.41.21.01.21.11.60.8-0.90.90.1
Time to tail flick, vehicle, before self-admin0.90.93.9-0.61.00.41.0-0.40.70.20.30.70.90.70.50.40.70.91.4-2.02.0-0.3
Time to tail flick, vehicle, after self-admin0.60.81.4-0.7-1.0-0.9-0.8-0.9-0.8-1.2-0.8-0.9-0.9-1.1-1.2-1.0-1.0-0.7-0.31.0-1.0-0.8
Time to tail flick, test, before self-admin0.20.20.8-0.30.60.60.30.20.90.30.60.30.40.30.30.10.10.3-0.2-0.10.10.7
Time to tail flick, test, after self-admin1.01.02.2-1.5-0.6-1.0-1.1-1.10.4-0.9-1.2-1.1-0.8-1.2-0.7-1.0-1.1-1.30.11.1-1.10.5
Delta time to tail flick, vehicle, before/after SA1.61.66.8-0.5-0.9-1.0-1.2-0.6-0.6-1.2-1.1-1.2-1.1-1.2-0.9-0.9-1.3-1.3-0.42.6-2.60.4
Delta time to tail flick, test, before/after SA0.20.21.6-0.40.1-0.5-0.0-0.50.3-0.1-0.9-0.2-0.0-0.20.10.00.1-0.21.30.1-0.1-0.1
Tibia length0.41.03.91.4-0.90.10.01.0-1.60.90.60.5-0.40.40.10.11.10.8-1.4-1.21.2-2.0
Ambulatory time before self-admin0.10.20.8-0.30.3-0.10.2-0.30.20.3-0.30.10.10.20.20.10.60.40.7-0.50.5-0.9
Ambulatory time after self-admin0.20.31.00.5-0.00.70.20.80.00.80.90.50.30.50.40.30.60.2-1.0-0.50.5-0.1
Bone: tissue strength0.10.10.50.70.50.20.40.40.00.30.10.40.20.40.40.50.60.40.4-0.20.2-0.4
Total heroin consumption0.00.00.1-0.4-0.3-0.2-0.2-0.2-0.4-0.2-0.1-0.1-0.2-0.1-0.2-0.3-0.1-0.20.0-0.00.0-0.1
Bone: trabecular number0.50.85.4-0.81.3-0.40.3-0.81.30.2-1.40.10.4-0.10.70.20.6-0.42.30.6-0.60.7
Bone: trabecular spacing0.60.84.01.3-0.70.60.11.1-1.00.21.70.5-0.10.4-0.20.1-0.10.5-2.0-1.01.0-0.2
Bone: trabecular thickness0.50.64.3-0.41.2-0.00.6-0.31.30.4-0.90.20.70.30.80.60.80.32.1-0.10.10.1
Bone: trabecular tissue density0.50.73.40.3-0.6-0.1-0.80.2-0.4-0.20.4-0.3-0.8-0.7-0.2-0.7-0.4-0.9-1.91.7-1.70.3
Water consumed over 24 hours0.20.30.7-0.3-0.7-0.5-0.5-0.4-0.8-0.7-0.3-0.5-0.5-0.4-0.7-0.5-0.5-0.2-0.40.7-0.7-0.7
Number of responses in last shaping day1.92.16.4-0.3-2.0-1.1-1.7-0.6-1.9-1.4-0.4-1.4-1.7-1.4-1.8-1.5-1.5-1.3-2.50.8-0.8-1.4