Fhod1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	alternative TSS	XM_039097608.2	0.3	0.22	6.7e-05	0.02	0.02	0.03	0.02	9.6e-04	3.6e-04	1.6e-05	3.4e-04
2	NAcc	alternative TSS	XM_039097608.2	0.18	0.15	5.9e-05	0.01	0.03	0.03	0.02	3.4e-03	1.0e-04	1.4e-05	2.4e-04
3	NAcc	mRNA stability	Fhod1	0.13	0.08	0.0e+00	0.11	0.11	0.11	0.11	6.3e-16	3.1e-16	6.9e-17	9.7e-17
4	Adipose	gene expression	Fhod1	0.27	0.18	0.0e+00	0.18	0.18	0.17	0.18	6.1e-20	1.5e-19	1.1e-18	7.2e-20
5	LHb	mRNA stability	Fhod1	0.32	0.21	1.9e-05	0.16	0.19	0.21	0.18	9.7e-05	2.9e-05	8.2e-06	5.2e-05
6	Brain	mRNA stability	Fhod1	0.36	0.18	0.0e+00	0.28	0.3	0.3	0.3	1.5e-26	7.0e-28	2.3e-28	3.0e-28
7	Brain	gene expression	Fhod1	0.03	0.04	8.0e-03	0.02	0.02	0.01	0.01	9.8e-03	5.1e-03	3.9e-02	1.2e-02
8	PL	mRNA stability	Fhod1	0.08	0.06	1.1e-11	0.08	0.09	0.07	0.09	1.2e-08	1.8e-10	1.9e-08	8.8e-10
9	BLA	mRNA stability	Fhod1	0.05	0.05	2.3e-03	0.04	0.04	0.03	0.04	5.7e-03	2.9e-03	8.2e-03	5.2e-03
10	NAcc	alternative TSS	NM_001395129.1	0.1	0.13	3.3e-03	0.02	0.01	0.02	0.02	1.2e-03	2.4e-02	3.2e-04	1.6e-03
11	NAcc	alternative TSS	NM_001395129.1	0.1	0.13	2.3e-03	0.02	0.01	0.04	0.02	6.5e-04	2.1e-02	3.0e-06	5.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10	11
Bone: apparent density	0.0	0.1	0.2	0.2	0.1	-0.3	0.5	0.1	-0.4	0.4	-0.2	-0.1	-0.2	0.0
Area under the delay curve	0.2	0.3	1.9	-0.3	-0.3	0.2	-0.1	-1.4	-0.0	-0.1	-0.1	-0.2	0.8	0.2
BMI with tail	0.0	0.1	0.3	0.5	0.5	-0.5	-0.1	-0.4	-0.3	0.3	-0.2	-0.2	-0.5	-0.2
BMI without tail	0.0	0.1	0.3	-0.4	-0.4	0.1	-0.6	-0.3	0.1	-0.0	-0.0	-0.1	0.3	0.6
Body weight	0.3	1.4	2.1	1.4	1.4	-1.4	1.1	-1.0	-1.3	1.2	-1.2	-1.2	-1.2	-0.3
Weight adjusted by age	0.8	1.2	4.0	-1.4	-1.5	0.3	0.0	1.1	-0.1	0.1	-0.1	-0.1	2.0	1.8
Bone surface	1.2	2.1	2.8	1.7	1.6	-1.6	1.7	-1.5	-1.6	1.6	-1.5	-1.4	-1.1	0.0
Bone volume	0.8	1.4	2.1	1.2	1.2	-1.4	1.4	-1.1	-1.4	1.5	-1.3	-1.2	-0.4	0.4
Breakpoint value in progressive ratio session	2.0	2.4	5.0	-1.8	-1.9	1.6	-1.1	2.2	1.4	-1.5	1.7	1.7	0.8	-0.5
Number of licking bursts	0.5	0.7	1.1	0.9	0.9	-0.9	1.0	-1.1	-0.9	0.9	-1.0	-0.9	-0.5	0.2
Context. condit. distance diff. score	0.1	0.2	0.9	0.1	0.2	0.2	-0.2	-0.4	0.3	-0.2	0.1	0.1	-0.8	-1.0
Locomotion velocity, session 1	0.1	0.1	0.2	0.3	0.4	-0.2	0.1	-0.5	-0.0	0.2	-0.3	-0.3	-0.0	0.1
Locomotion distance, session 1	0.2	0.3	1.1	-0.5	-0.5	0.4	-0.5	0.3	0.5	-0.3	0.3	0.2	1.0	0.8
Locomotion velocity, session 2	0.7	0.9	1.3	-1.1	-1.1	1.0	-1.0	0.6	1.1	-0.9	0.8	0.8	1.1	0.5
Locomotion distance, session 2	0.3	0.4	1.4	-0.6	-0.6	0.4	-0.5	0.4	0.6	-0.4	0.2	0.2	1.2	1.1
Locomotion velocity, session 3	0.3	0.4	0.5	-0.7	-0.7	0.7	-0.6	0.4	0.6	-0.6	0.6	0.6	0.7	0.4
Locomotion distance, session 3	0.0	0.0	0.1	-0.1	-0.1	0.2	-0.2	-0.1	0.2	-0.2	0.0	0.0	-0.2	0.0
Stereotopy head waving bouts, day 3	0.2	0.2	0.8	0.3	0.2	-0.4	0.3	-0.4	-0.4	0.3	-0.3	-0.3	0.6	0.9
Stereotopy head waving duration, day 3	0.4	0.5	0.8	0.7	0.7	-0.9	0.8	-0.6	-0.8	0.8	-0.7	-0.7	0.3	0.6
Locomotion velocity, session 7	0.1	0.1	1.1	-0.1	-0.0	0.2	-0.0	0.0	0.2	-0.0	0.2	0.2	-0.4	-1.0
Locomotion distance, session 7	0.1	0.2	0.8	-0.0	0.0	0.3	-0.1	-0.1	0.1	-0.2	0.2	0.2	-0.9	-0.8
Stereotopy head waving bouts, day 7	0.1	0.1	0.3	0.5	0.5	-0.5	0.5	-0.3	-0.5	0.4	-0.3	-0.2	-0.1	0.2
Stereotopy head waving duration, day 7	0.5	0.5	0.9	0.9	0.9	-0.9	0.9	-0.5	-0.9	0.7	-0.6	-0.6	-0.5	0.2
Locomotion velocity, session 8	0.1	0.2	0.5	-0.5	-0.6	0.2	-0.0	0.7	0.1	-0.1	0.3	0.4	0.7	0.2
Locomotion distance, session 8	0.2	0.4	0.8	-0.5	-0.4	0.8	-0.8	0.3	0.9	-0.8	0.6	0.6	-0.1	-0.4
Degree of sensitization distance	0.1	0.1	0.4	0.2	0.2	-0.1	0.1	-0.2	-0.1	0.1	-0.1	-0.0	-0.6	-0.5
Degree of sensitization stereotypy	0.2	0.3	0.4	0.7	0.7	-0.6	0.6	-0.4	-0.6	0.5	-0.5	-0.4	-0.3	0.1
Conditioned locomotion	2.0	2.3	3.2	1.8	1.7	-1.8	1.5	-1.7	-1.6	1.6	-1.6	-1.6	-0.3	1.0
Cocaine response after cond. corrected	0.2	0.2	0.4	0.4	0.4	-0.6	0.5	-0.0	-0.6	0.6	-0.6	-0.5	0.2	0.2
Cocaine response after cond. not corrected	0.0	0.0	0.1	-0.0	0.1	-0.1	0.1	0.4	-0.1	0.0	-0.0	-0.0	0.1	0.0
Cocaine response before conditioning	0.9	1.0	1.9	-0.8	-0.6	1.4	-1.0	0.7	1.2	-1.3	1.1	1.1	-0.8	-0.9
Saline control response	3.9	5.3	7.3	2.4	2.3	-2.6	2.2	-2.7	-2.2	2.5	-2.5	-2.5	0.1	2.1
Bone: connectivity density	0.1	0.1	0.3	-0.1	-0.1	0.3	0.0	0.4	0.1	-0.2	0.3	0.4	-0.5	-0.5
Bone: cortical apparent density	0.7	1.0	1.6	-1.1	-1.1	1.1	-1.0	1.1	0.9	-1.1	1.2	1.3	0.2	-0.5
Bone: cortical area	0.2	0.3	0.6	0.4	0.4	-0.7	0.5	-0.6	-0.6	0.8	-0.7	-0.7	0.5	0.4
Bone: cortical porosity	0.2	0.3	0.6	-0.5	-0.6	0.3	-0.7	0.4	0.5	-0.4	0.3	0.3	0.8	0.5
Bone: cortical porosity	0.2	0.2	0.5	-0.5	-0.5	0.3	-0.7	0.4	0.5	-0.4	0.3	0.3	0.7	0.5
Bone: cortical thickness	0.1	0.1	0.2	-0.0	-0.1	-0.4	0.3	-0.1	-0.4	0.5	-0.2	-0.2	0.4	-0.2
Bone: cortical thickness	0.0	0.0	0.1	0.1	0.1	-0.3	-0.2	-0.3	-0.1	0.1	-0.1	-0.1	-0.1	-0.3
Bone: cortical tissue density	0.8	1.1	1.7	-1.1	-1.2	1.1	-1.0	1.1	0.9	-1.1	1.3	1.3	0.3	-0.4
Condit. Reinf. active minus inactive responses	3.5	3.9	5.5	-2.2	-2.1	2.3	-2.2	2.1	2.3	-2.2	2.1	2.1	0.2	-0.7
Condit. Reinf. active-inactive response ratio	2.9	3.1	4.3	-1.7	-1.6	2.1	-2.0	1.7	2.0	-2.1	1.9	1.9	-0.6	-1.3
Condit. Reinf. active responses	2.4	3.0	4.4	-1.9	-1.8	2.1	-2.0	1.7	2.1	-1.9	1.8	1.8	0.6	-0.1
Condit. Reinf. inactive responses	0.2	0.3	0.6	-0.5	-0.5	0.5	-0.5	0.5	0.5	-0.5	0.4	0.4	0.7	0.6
Incentive salience index mean	1.8	2.2	3.3	-1.6	-1.6	1.8	-1.7	1.5	1.8	-1.6	1.6	1.6	0.2	-0.4
Condit. Reinf. lever presses	0.1	0.2	0.4	-0.4	-0.4	0.5	-0.4	0.3	0.6	-0.4	0.5	0.5	0.0	-0.1
Condit. Reinf. active minus inactive responses	0.6	0.7	1.1	0.6	0.6	-1.0	0.6	-0.8	-0.9	1.0	-1.1	-1.1	0.5	1.0
Condit. Reinf. active-inactive response ratio	0.4	0.5	0.8	0.6	0.6	-0.8	0.7	-0.6	-0.9	0.8	-0.8	-0.8	-0.4	-0.2
Condit. Reinf. active responses	0.4	0.5	1.7	0.4	0.4	-0.8	0.2	-0.6	-0.6	0.8	-0.8	-0.9	0.7	1.3
Condit. Reinf. inactive responses	0.4	0.5	2.0	-0.6	-0.6	0.4	-0.8	0.3	0.5	-0.4	0.3	0.3	1.2	1.4
Condit. Reinf. lever presses	2.2	3.0	4.1	-2.0	-2.0	1.9	-1.9	1.8	1.8	-1.7	1.8	1.8	1.1	-0.1
Condit. Reinf. lever reinforcers received	0.2	0.2	1.2	-0.1	-0.2	-0.3	-0.3	-0.1	-0.1	0.3	-0.3	-0.3	1.0	1.1
Conditioned reinforcement - actives	0.6	1.1	2.4	-1.0	-0.9	0.9	-1.5	0.5	1.1	-1.1	0.9	0.8	1.3	0.9
Conditioned reinforcement - inactives	0.4	0.7	2.7	1.0	1.0	-0.5	0.3	-0.2	-0.3	0.2	-0.2	-0.2	-1.7	-1.4
Conditioned locomotion	0.7	0.9	2.0	1.4	1.4	-1.1	0.8	-1.0	-0.9	0.9	-0.9	-0.8	-0.3	0.6
Patch foraging indifference point 0 sec	2.8	5.1	8.3	2.4	2.5	-2.5	2.3	-2.9	-2.3	2.3	-2.5	-2.5	-0.7	0.7
Patch foraging indifference point AUC	1.8	2.6	3.9	1.9	2.0	-1.7	1.5	-1.9	-1.6	1.7	-1.6	-1.6	-0.7	0.8
Delay disc. indifference point, 0s delay	0.7	0.8	1.3	-1.1	-1.1	1.0	-0.9	0.0	0.8	-0.9	0.9	0.8	1.1	-0.1
Delay disc. indifference point, 16s delay	0.3	0.3	1.6	0.2	0.2	-0.3	0.2	-1.3	-0.3	0.3	-0.6	-0.7	0.7	0.7
Delay disc. indifference point, 2s delay	0.5	0.6	2.8	0.7	0.7	-0.4	0.6	-1.7	-0.5	0.4	-0.4	-0.4	-0.6	-0.9
Delay disc. indifference point, 24s delay	0.3	0.4	1.4	0.6	0.6	-0.2	0.0	-1.2	-0.1	0.0	-0.2	-0.2	-0.9	-1.0
Delay disc. indifference point, 4s delay	0.3	0.4	0.9	-0.6	-0.6	0.7	-0.4	-0.7	0.4	-0.6	0.6	0.6	0.3	-0.9
Delay disc. indifference point, 8s delay	0.6	0.7	3.5	-0.9	-1.0	0.4	-0.0	-0.8	-0.1	-0.1	-0.1	-0.2	1.9	1.3
Indifference point function ln k	0.2	0.3	0.6	-0.4	-0.4	0.6	-0.6	0.4	0.7	-0.7	0.6	0.5	-0.3	-0.8
Indifference point function log k	0.2	0.3	0.6	-0.4	-0.4	0.6	-0.6	0.4	0.7	-0.7	0.6	0.5	-0.3	-0.8
Patch foraging total patch changes 0 sec	2.6	4.9	7.2	2.3	2.3	-2.5	2.3	-2.7	-2.3	2.3	-2.5	-2.5	-0.4	0.9
Patch foraging total patch changes 12 sec	3.0	3.9	4.9	2.2	2.2	-2.1	2.1	-2.2	-2.0	2.0	-2.0	-2.1	-1.6	0.6
Patch foraging total patch changes 18 sec	2.5	3.8	4.9	2.2	2.2	-2.2	2.0	-2.2	-2.0	2.1	-2.1	-2.1	-0.6	1.1
Patch foraging total patch changes 24 sec	0.2	0.3	1.2	0.5	0.4	-0.5	1.1	-0.4	-0.7	0.6	-0.5	-0.5	-0.5	0.2
Patch foraging total patch changes 6 sec	1.9	2.8	4.6	1.8	1.8	-1.8	1.9	-2.1	-1.8	1.8	-1.7	-1.7	-0.5	0.7
Patch foraging time to switch 0 sec	0.7	1.3	2.0	-1.3	-1.3	1.4	-1.0	0.9	1.2	-1.2	1.4	1.4	0.0	-0.8
Patch foraging water rate 0 sec	1.2	2.6	3.7	1.9	1.9	-1.9	1.8	-0.9	-1.8	1.7	-1.8	-1.8	-0.8	0.6
Patch foraging water rate 12 sec	0.2	0.4	1.4	0.7	0.7	-0.4	1.0	0.0	-0.6	0.4	-0.5	-0.5	-1.2	-0.2
Patch foraging water rate 18 sec	0.7	1.1	6.2	0.9	1.0	-0.3	0.9	-0.6	-0.5	0.2	-0.4	-0.4	-2.5	-1.6
Patch foraging water rate 24 sec	0.0	0.1	0.3	0.1	0.1	-0.0	0.4	0.1	-0.2	0.1	-0.2	-0.3	0.0	0.5
Patch foraging water rate 6 sec	0.7	1.1	1.8	1.2	1.2	-1.1	1.3	-0.3	-1.2	1.0	-1.0	-1.0	-1.1	-0.2
Seeking ratio, delayed vs. immediate footshock	2.1	2.6	3.8	1.7	1.7	-1.8	1.7	-1.9	-1.7	1.7	-1.9	-1.9	-0.3	0.4
Distance traveled before self-admin	2.4	3.2	11.2	1.6	1.6	-1.0	1.2	-2.3	-1.0	0.9	-0.5	-0.4	-3.3	-3.1
Distance traveled after self-admin	0.2	0.2	0.7	0.2	0.3	-0.2	0.5	-0.8	-0.4	0.3	-0.2	-0.2	-0.8	-0.5
Extensor digitorum longus weight	0.5	2.1	3.5	-1.3	-1.4	1.6	-1.5	1.9	1.6	-1.6	1.6	1.6	-0.3	-0.8
Bone: elastic displacement	1.3	1.5	2.1	1.3	1.2	-1.5	1.4	-0.9	-1.4	1.4	-1.4	-1.4	-0.1	0.6
Bone: elastic work	0.4	0.5	0.8	0.8	0.8	-0.9	0.8	-0.4	-0.9	0.9	-0.8	-0.8	-0.3	0.1
Bone: endosteal estimation	0.1	0.3	0.7	0.8	0.8	-0.5	0.2	-0.7	-0.3	0.3	-0.5	-0.6	-0.6	0.2
Bone: endosteal perimeter	0.2	0.4	0.8	0.7	0.8	-0.7	0.3	-0.8	-0.4	0.6	-0.8	-0.9	0.1	0.7
Epididymis fat weight	2.4	8.4	12.3	3.4	3.5	-2.9	2.8	-3.2	-2.8	2.6	-2.9	-2.9	-3.2	-0.2
Delta time in closed arm before/after self-admin	0.2	0.2	0.9	0.3	0.3	-0.2	0.4	-0.9	-0.3	0.3	-0.4	-0.5	0.2	0.6
Delta time in open arm before/after self-admin	0.5	0.5	2.3	0.0	0.0	0.3	0.1	1.0	0.2	-0.2	0.4	0.5	-1.5	-1.4
Diff in mean of infusions in LGA sessions	0.5	0.6	0.9	-0.9	-0.9	0.8	-0.4	0.8	0.7	-0.7	0.9	1.0	0.4	-0.5
Delay discount exponential model param	0.2	0.2	1.7	0.3	0.3	-0.3	0.1	1.3	-0.1	0.2	0.0	0.1	-0.6	-0.0
Extinction: sum of active levers before priming	1.2	1.3	3.3	-1.0	-1.0	0.8	-1.1	1.8	1.0	-0.9	0.9	0.9	1.8	0.8
Active lever presses in extinction session 6	0.4	0.4	2.5	-0.3	-0.3	0.0	-0.2	-0.5	-0.0	0.1	-0.1	-0.2	1.6	0.9
Bone: final force	0.8	1.3	2.1	-1.4	-1.4	1.2	-1.3	1.1	1.2	-1.1	1.2	1.2	1.1	0.1
Bone: final moment	0.3	0.5	0.8	-0.9	-0.9	0.8	-0.8	0.6	0.8	-0.7	0.8	0.8	0.7	0.2
Food consumed during 24 hour testing period	0.4	0.6	1.3	0.8	0.9	-0.6	0.4	-1.1	-0.4	0.5	-1.0	-1.1	-0.4	0.6
Glucose	1.4	2.2	3.0	-1.5	-1.5	1.7	-1.4	1.7	1.5	-1.7	1.7	1.7	-0.2	-0.9
Heart weight	0.0	0.0	0.1	-0.1	-0.1	-0.0	-0.2	0.2	0.1	-0.2	0.2	0.2	-0.0	-0.3
Delay discount hyperbolic model param	0.2	0.3	1.5	0.4	0.5	-0.4	0.2	1.2	-0.2	0.3	-0.1	-0.1	-0.7	0.1
Intermittent access intake day 1-15 change	1.0	2.1	3.7	-1.7	-1.6	1.6	-1.9	1.0	1.6	-1.6	1.4	1.3	1.0	-0.0
Intermittent access intake escalation	1.1	2.3	3.8	-1.8	-1.7	1.8	-1.9	1.1	1.7	-1.7	1.5	1.4	1.0	-0.1
Intermittent access intake escalation 2	0.8	0.9	1.8	-1.1	-1.1	1.1	-1.3	0.6	1.1	-1.1	0.9	0.8	0.4	-0.5
Intermitt. access day 1 inactive lever presses	0.0	0.1	0.2	-0.4	-0.3	0.3	-0.4	-0.1	0.3	-0.2	0.0	-0.1	0.5	0.2
Intermitt. access day 15 inactive lever presses	0.3	0.5	2.9	0.3	0.4	0.3	-0.2	0.2	0.3	-0.4	0.5	0.5	-1.3	-1.7
Intermitt. access escalation Index	0.2	0.3	1.1	0.4	0.4	-0.3	1.1	-0.7	-0.6	0.6	-0.6	-0.6	0.0	0.4
Intermittent access day 1 total infusions	0.3	0.5	2.4	-0.4	-0.3	0.2	-0.5	-0.3	0.3	-0.2	-0.0	-0.1	1.6	1.5
Intermittent access day 15 total infusions	1.7	2.6	4.6	-1.8	-1.6	1.6	-2.2	0.7	1.7	-1.6	1.3	1.2	2.1	1.1
Intermittent access terminal intake (last 3 days)	2.2	2.9	6.0	-1.8	-1.6	1.9	-2.4	1.0	2.1	-2.0	1.6	1.5	1.3	0.1
Intermittent access total infusions	2.1	2.5	4.6	-1.7	-1.6	1.6	-2.1	0.8	1.7	-1.6	1.3	1.2	2.2	1.0
Intermittent access day 1 locomotion	1.2	1.6	2.9	1.1	1.1	-1.2	1.0	-1.5	-1.2	1.2	-1.4	-1.4	0.7	1.7
Intermittent access day 15 total locomotion	0.2	0.4	0.8	0.5	0.6	-0.5	0.2	-0.9	-0.5	0.5	-0.6	-0.6	0.6	0.7
Intermittent access total locomotion	0.2	0.2	1.2	0.1	0.1	-0.2	-0.2	-0.4	-0.1	0.2	-0.2	-0.2	1.1	0.8
Intermittent access standard deviation	0.2	0.3	0.5	0.7	0.7	-0.6	0.4	-0.4	-0.5	0.5	-0.5	-0.5	-0.7	-0.5
Left kidney weight	1.3	6.0	8.7	-2.1	-2.0	2.5	-2.2	2.7	2.5	-2.6	2.7	2.7	-1.4	-2.9
Right kidney weight	1.3	6.0	7.4	-2.5	-2.4	2.6	-2.4	2.6	2.6	-2.6	2.7	2.7	-0.6	-2.5
Cocaine induced anxiety	2.0	2.9	4.7	2.1	2.0	-2.2	1.8	-1.5	-1.9	1.9	-1.7	-1.6	-0.3	0.2
Post-drug Anxiety	0.6	0.6	1.1	1.1	1.0	-0.9	0.9	-0.5	-0.8	0.7	-0.7	-0.6	-0.7	-0.5
Baseline Anxiety	1.1	1.2	2.5	-1.2	-1.1	1.6	-1.2	0.8	1.3	-1.5	1.1	1.0	-0.1	-0.4
Tail length	0.0	0.2	0.9	-0.3	-0.2	0.0	0.1	-0.4	-0.1	0.1	-0.3	-0.4	0.5	0.9
Length with tail	0.2	0.8	1.7	0.9	1.0	-0.9	1.3	-0.6	-1.0	0.8	-0.9	-0.9	-1.1	-0.2
Length without tail	0.6	2.0	3.3	1.8	1.8	-1.6	1.6	-1.1	-1.4	1.3	-1.3	-1.3	-1.6	-0.7
Times rat made contact with spout	1.3	1.5	2.2	0.9	0.9	-1.3	1.3	-1.5	-1.3	1.3	-1.5	-1.5	0.5	1.2
Lifetime Intake	1.8	2.1	4.3	-1.6	-1.5	1.5	-1.8	0.6	1.6	-1.5	1.2	1.1	2.1	1.1
Liver weight, left	0.4	0.6	2.3	0.6	0.5	-0.6	1.0	-0.4	-0.8	0.6	-0.5	-0.5	-1.5	-0.9
Liver weight, right	0.5	0.8	1.2	1.0	1.0	-1.0	1.1	-0.9	-0.9	0.9	-0.9	-0.9	-0.4	0.4
Locomotor activity	2.3	3.5	4.9	2.2	2.1	-2.2	1.9	-2.1	-2.1	2.2	-1.9	-1.9	-0.5	0.7
Locomotor testing distance	1.7	3.0	4.2	1.7	1.6	-2.0	1.6	-1.8	-1.9	2.0	-1.9	-1.8	0.6	1.7
Locomotor testing rearing	0.2	0.4	0.8	0.8	0.7	-0.9	0.5	-0.1	-0.8	0.7	-0.5	-0.4	-0.9	-0.1
Locomotion in novel chamber	2.1	2.7	4.2	1.8	1.9	-1.8	1.5	-2.1	-1.6	1.7	-1.8	-1.8	-1.0	-0.5
Locomotion in novel chamber post-restriction	1.6	2.6	4.5	1.3	1.3	-1.6	1.4	-2.1	-1.7	1.7	-1.7	-1.8	1.0	1.8
Fecal boli incidents, locomotor time 1	1.0	1.4	5.2	0.3	0.2	-1.0	1.0	-0.8	-1.2	1.2	-1.2	-1.3	1.1	2.3
Change in fecal boli incidents, locomotor task	0.5	0.5	1.4	-0.3	-0.2	0.7	-0.8	0.4	0.8	-0.8	0.7	0.7	-0.7	-1.2
Time >=10cm from walls, locomotor time 1	0.8	0.8	3.4	-0.3	-0.4	-0.4	0.5	-0.8	-0.8	0.7	-0.9	-0.9	1.2	1.8
Bouts of movement, locomotor time 1	0.0	0.0	0.1	0.1	0.1	-0.3	0.1	0.2	-0.2	0.2	-0.2	-0.2	0.0	-0.0
Total resting periods, locomotor time 1	0.0	0.0	0.1	-0.1	-0.1	0.0	-0.2	0.4	0.1	-0.1	0.1	0.1	0.0	-0.1
Rest time, locomotor task time 1	0.3	0.4	1.1	-0.5	-0.5	0.5	-0.5	1.1	0.5	-0.4	0.5	0.5	-0.9	-0.9
Distance moved, locomotor task time 1	0.2	0.2	0.9	0.5	0.5	-0.5	0.5	-1.0	-0.4	0.4	-0.5	-0.5	0.0	-0.0
Vertical activity count, locomotor time 1	0.7	1.7	4.6	1.6	1.6	-1.4	1.1	-2.1	-1.2	1.1	-1.3	-1.3	0.0	0.4
Time >=10cm from walls, locomotor time 2	0.8	1.2	4.0	-1.4	-1.5	0.8	-0.6	1.1	0.5	-0.6	0.7	0.7	2.0	1.3
Bouts of movement, locomotor time 2	0.4	0.6	1.0	-0.5	-0.6	0.8	-1.0	0.6	1.0	-1.0	1.0	1.0	0.0	-0.8
Total resting periods, locomotor time 2	0.5	0.9	1.4	-0.7	-0.7	0.9	-1.1	0.8	1.1	-1.1	1.2	1.2	-0.0	-1.0
Rest time, locomotor task time 2	0.6	0.8	1.2	-1.0	-1.0	0.9	-1.0	1.1	0.8	-0.8	0.7	0.7	0.8	0.3
Distance moved, locomotor task time 2	0.7	0.9	1.3	1.1	1.1	-1.0	1.1	-0.8	-0.9	0.9	-0.7	-0.6	-1.1	-0.8
Vertical activity count, locomotor time 2	1.2	1.7	3.0	1.7	1.7	-1.5	1.3	-1.5	-1.2	1.2	-1.2	-1.1	-1.0	-0.4
Light reinforcement 1	2.1	5.2	7.3	2.7	2.7	-2.6	2.4	-2.5	-2.4	2.4	-2.4	-2.4	-0.8	0.5
Light reinforcement 2	2.2	3.4	6.9	1.9	1.9	-1.9	1.9	-2.6	-2.0	1.9	-2.0	-2.0	-0.4	0.5
Bone: marrow area	0.1	0.2	0.6	0.7	0.8	-0.4	0.1	-0.6	-0.3	0.3	-0.5	-0.5	-0.6	0.2
Bone: maximum diameter	0.4	0.7	1.2	0.7	0.7	-1.0	0.4	-1.0	-0.7	0.9	-1.0	-1.1	0.8	1.1
Bone: maximum force	0.2	0.4	0.6	-0.7	-0.7	0.7	-0.6	0.7	0.6	-0.6	0.7	0.8	0.2	-0.2
Bone: maximum moment	0.0	0.0	0.1	-0.1	-0.1	0.2	-0.1	0.2	0.2	-0.2	0.3	0.3	-0.2	-0.1
Mean time between licks in bursts	0.0	0.1	0.3	0.1	0.2	-0.0	0.1	-0.3	-0.1	0.1	-0.2	-0.2	-0.5	-0.5
Mean num. licks in bursts	0.0	0.1	0.3	-0.1	-0.1	-0.0	-0.1	-0.1	-0.0	-0.0	-0.1	-0.1	0.5	0.5
Cd content in liver	0.4	0.4	2.2	0.2	0.3	0.2	-0.3	-0.1	0.3	-0.3	0.3	0.4	-1.2	-1.5
Co content in liver	0.0	0.0	0.1	-0.0	0.0	0.1	-0.3	0.1	0.2	-0.2	0.2	0.2	-0.1	-0.2
Cu content in liver	0.6	0.7	1.1	-0.3	-0.2	1.0	-0.7	0.3	1.0	-1.0	0.9	0.9	-1.1	-1.0
Fe content in liver	1.8	2.2	3.1	1.6	1.6	-1.6	1.7	-1.8	-1.6	1.6	-1.5	-1.4	-0.0	0.8
K content in liver	0.2	0.2	0.4	-0.5	-0.5	0.4	-0.6	0.3	0.5	-0.4	0.2	0.2	0.7	0.5
Mg content in liver	0.4	0.4	0.6	0.6	0.6	-0.7	0.6	-0.5	-0.6	0.6	-0.7	-0.8	0.3	0.7
Mn content in liver	0.4	0.5	0.8	0.5	0.4	-0.9	0.9	-0.3	-0.9	0.8	-0.8	-0.8	0.3	0.6
Na content in liver	0.1	0.2	0.7	-0.3	-0.4	0.2	0.0	0.1	0.1	-0.1	0.0	0.0	0.9	0.8
Rb content in liver	0.1	0.1	0.3	-0.1	-0.1	0.4	-0.3	0.4	0.5	-0.5	0.4	0.4	-0.2	-0.4
Se content in liver	0.1	0.1	0.4	-0.4	-0.4	0.2	-0.1	0.6	0.1	-0.2	0.2	0.2	0.5	0.5
Sr content in liver	1.0	0.9	1.4	0.9	0.9	-1.1	1.2	-0.7	-1.0	1.0	-1.1	-1.1	-0.1	0.6
Zn content in liver	1.3	1.4	3.0	-1.1	-1.0	1.4	-1.7	0.9	1.5	-1.4	1.3	1.2	0.3	-0.4
Bone: minimum diameter	0.1	0.2	0.6	0.3	0.2	-0.5	0.2	-0.3	-0.4	0.5	-0.5	-0.5	0.7	0.8
Time in familiar zone, hab. session 1	0.7	0.7	3.6	0.7	0.8	-0.5	0.5	-0.1	-0.6	0.4	-0.5	-0.5	-1.9	-1.2
Time in novel zone, hab. session 1	0.7	0.7	3.4	-0.8	-0.9	0.5	-0.5	0.3	0.5	-0.4	0.5	0.6	1.8	1.1
Total zone transitions, hab. session 1	0.7	1.0	1.3	1.0	1.0	-1.1	1.0	-0.8	-1.0	1.1	-1.1	-1.2	0.0	1.1
Total locomotion distance, hab. session 1	1.0	1.4	2.0	1.4	1.4	-1.3	1.2	-1.4	-1.2	1.3	-1.3	-1.3	-0.4	0.5
Locomotion velocity, hab. session 1	1.3	1.8	2.6	1.5	1.4	-1.4	1.3	-1.6	-1.2	1.4	-1.5	-1.5	-0.0	1.0
Time in familiar zone, hab. session 2	0.6	0.7	0.9	0.8	0.8	-0.9	0.9	-0.9	-0.9	0.9	-0.9	-0.9	-0.5	-0.4
Time in novel zone, hab. session 2	4.4	4.5	6.1	-2.4	-2.5	2.3	-2.1	2.5	2.1	-2.1	2.2	2.2	1.6	0.5
Total zone transitions, hab. session 2	1.7	2.2	3.0	1.2	1.1	-1.6	1.6	-1.3	-1.4	1.7	-1.6	-1.6	1.1	1.7
Total locomotion distance, hab. session 2	1.0	1.4	1.8	1.1	1.1	-1.3	1.2	-1.3	-1.0	1.3	-1.3	-1.3	0.5	1.1
Locomotion velocity, hab. session 2	1.0	1.3	1.7	1.1	1.0	-1.2	1.2	-1.3	-1.0	1.3	-1.3	-1.3	0.5	1.1
Novel to familiar place preference ratio	1.9	2.1	3.3	-1.2	-1.1	1.6	-1.5	1.3	1.4	-1.6	1.6	1.7	-0.8	-1.8
Novelty place preference	2.9	3.2	4.3	-1.7	-1.6	2.1	-1.8	1.7	1.8	-2.0	2.0	2.1	-0.3	-1.6
Time in novel zone, NPP test	2.7	2.9	4.0	-1.7	-1.6	2.0	-1.8	1.6	1.7	-1.9	2.0	2.0	-0.4	-1.6
Total zone transitions, NPP test	1.5	2.2	2.9	1.6	1.5	-1.7	1.6	-1.5	-1.5	1.7	-1.6	-1.6	0.1	1.2
Total locomotion distance, NPP test	0.8	1.1	1.6	1.1	1.1	-1.2	1.1	-1.1	-1.1	1.2	-1.2	-1.2	0.3	1.0
Locomotion velocity, NPP test	0.7	1.0	1.4	1.0	1.0	-1.1	1.0	-1.0	-1.0	1.2	-1.1	-1.1	0.4	0.9
Intraocular pressure	0.4	0.6	1.0	-0.3	-0.3	0.6	-0.8	1.0	0.7	-0.7	0.9	1.0	-0.7	-1.0
Delta distance traveled before/after self-admin	0.6	0.6	3.2	-0.7	-0.6	0.8	-0.6	1.8	0.7	-0.7	0.6	0.6	-0.2	-0.0
Delta ambulatory time before/after self-admin	1.0	1.3	2.3	-1.3	-1.2	1.1	-1.1	1.5	1.0	-1.0	0.8	0.7	1.3	1.0
Parametrial fat weight	6.7	15.8	23.0	4.8	4.8	-4.5	4.5	-3.7	-4.2	4.1	-4.0	-4.0	-3.0	0.4
Pavlov. Cond. lever latency	0.1	0.2	0.6	0.4	0.5	-0.3	0.2	-0.2	-0.3	0.1	-0.3	-0.3	-0.8	-0.5
Pavlov. Cond. magazine entry latency	0.6	0.8	1.5	-1.0	-1.0	0.9	-0.9	0.8	1.0	-0.7	0.7	0.7	1.2	0.8
Pavlov. Cond. change in total contacts	0.8	0.8	1.1	-1.0	-1.1	1.0	-0.9	0.8	1.0	-0.9	1.0	1.0	0.8	0.4
Pavlov. Cond. index score	0.4	0.6	1.1	-0.9	-0.9	0.7	-0.7	0.6	0.9	-0.5	0.6	0.6	1.0	0.7
Pavlov. Cond. latency score	0.4	0.5	1.2	-0.8	-0.8	0.6	-0.6	0.4	0.8	-0.4	0.5	0.5	1.1	0.8
Pavlov. Cond. lever contacts	0.7	0.8	1.5	-1.1	-1.1	0.9	-0.8	1.0	0.9	-0.7	0.8	0.8	1.2	0.6
Pavlov. Cond. magazine entry number	0.7	0.9	1.7	1.1	1.1	-0.9	0.9	-0.8	-1.0	0.8	-0.7	-0.7	-1.3	-0.9
Pavlov. Cond. intertrial magazine entries	0.2	0.3	0.4	0.6	0.6	-0.5	0.4	-0.6	-0.5	0.4	-0.5	-0.6	-0.2	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	1.0	-0.9	-0.9	0.8	-0.7	0.5	0.9	-0.6	0.7	0.7	1.0	0.7
Pavlov. Cond. response bias	0.4	0.5	1.5	-0.8	-0.9	0.6	-0.6	0.6	0.7	-0.5	0.5	0.5	1.2	0.8
Pavlov. Cond. lever latency	1.4	1.9	3.1	1.8	1.8	-1.4	1.5	-1.4	-1.3	1.3	-1.3	-1.3	-1.4	-0.3
Pavlov. Cond. magazine entry latency	3.3	4.0	5.9	-2.4	-2.3	2.3	-2.4	1.9	2.2	-2.0	2.0	2.0	1.2	-0.6
Pavlov. Cond. change in total contacts	1.6	2.6	3.6	-1.9	-1.9	1.7	-1.7	1.7	1.7	-1.6	1.7	1.7	0.8	-0.6
Pavlov. Cond. index score	3.3	4.4	6.4	-2.5	-2.5	2.3	-2.4	2.0	2.2	-2.1	2.1	2.1	1.5	-0.3
Pavlov. Cond. latency score	3.3	4.4	6.3	-2.5	-2.5	2.3	-2.4	2.1	2.2	-2.1	2.1	2.1	1.5	-0.3
Pavlov. Cond. lever contacts	1.6	2.2	3.4	-1.8	-1.8	1.6	-1.7	1.4	1.5	-1.4	1.4	1.4	1.4	0.2
Pavlov. Cond. magazine entry number	5.2	6.4	8.9	3.0	2.9	-2.8	2.9	-2.5	-2.7	2.6	-2.6	-2.6	-1.4	0.7
Pavlov. Cond. intertrial magazine entries	3.9	5.9	8.5	2.6	2.5	-2.9	2.2	-2.6	-2.6	2.7	-2.7	-2.7	-0.1	1.7
Pavlov. Cond. lever-magazine prob. diff.	3.7	5.0	7.1	-2.7	-2.6	2.4	-2.6	2.2	2.3	-2.2	2.2	2.2	1.7	-0.2
Pavlov. Cond. response bias	3.0	4.1	6.0	-2.5	-2.4	2.2	-2.3	1.9	2.1	-2.0	2.0	2.0	1.6	-0.2
Time in closed arm before self-admin	3.6	4.6	9.4	3.0	3.1	-2.5	1.8	-1.9	-2.0	2.0	-1.9	-1.9	-2.1	-0.4
Time in closed arm after self-admin	4.0	4.3	7.5	2.4	2.4	-2.0	1.9	-2.7	-1.9	1.9	-1.7	-1.7	-2.4	-1.1
Time in open arm before self-admin	2.0	2.2	5.1	-1.9	-1.9	1.6	-1.3	0.7	1.3	-1.3	1.2	1.2	2.3	0.9
Time in open arm after self-admin	1.0	1.1	2.2	-1.3	-1.3	1.1	-0.7	1.5	0.9	-0.8	0.9	0.9	1.1	0.5
Bone: periosteal estimation	0.2	0.5	0.7	0.8	0.8	-0.8	0.5	-0.8	-0.7	0.7	-0.8	-0.8	-0.2	0.3
Bone: periosteal perimeter	0.6	1.1	1.4	1.1	1.1	-1.2	0.9	-1.1	-1.0	1.1	-1.2	-1.2	0.1	0.7
Bone: post-yield work	0.8	1.1	2.2	1.3	1.3	-0.9	1.2	-1.2	-0.9	0.8	-0.8	-0.8	-1.5	-0.3
Progressive ratio test 1 active lever presses	2.8	3.5	5.8	-2.1	-2.0	2.0	-2.3	1.1	2.0	-1.9	1.6	1.5	2.4	1.2
Progressive ratio test 1 breakpoint	2.5	3.0	5.1	-1.9	-1.8	1.9	-2.2	1.0	1.9	-1.8	1.5	1.4	2.3	1.1
Progressive ratio test 1 inactive lever presses	0.6	0.9	4.5	-0.7	-0.7	0.3	-0.7	-0.1	0.3	-0.3	0.1	0.0	2.1	1.9
Progressive ratio test 2 active lever presses	2.6	3.1	7.9	-2.0	-1.9	1.7	-2.1	0.5	1.7	-1.6	1.2	1.0	2.8	1.8
Progressive ratio test 2 breakpoint	2.8	3.2	7.9	-2.0	-1.9	1.7	-2.2	0.6	1.7	-1.6	1.2	1.1	2.8	1.8
Progressive ratio test 2 inactive lever presses	0.2	0.4	1.9	-0.5	-0.4	0.4	-0.6	0.1	0.4	-0.4	0.3	0.3	1.4	0.8
Incentive Sensitization - Responses	0.7	1.0	2.9	-1.1	-1.0	0.9	-1.4	0.1	1.0	-0.9	0.6	0.5	1.7	0.8
Incentive Sensitization - Breakpoint	0.9	1.2	3.6	-1.2	-1.2	1.0	-1.5	0.1	1.1	-1.0	0.7	0.6	1.9	0.9
Sum of active levers in priming session hrs 5-6	0.5	0.4	0.9	-0.8	-0.8	0.6	-0.6	1.0	0.6	-0.5	0.6	0.7	0.8	0.0
Progressive ratio	0.1	0.2	1.9	-0.2	-0.2	0.0	0.2	0.1	-0.1	0.1	0.3	0.4	-0.3	-1.4
Food seeking constrained by brief footshock	1.6	2.0	3.4	-1.8	-1.8	1.5	-1.1	1.8	1.3	-1.3	1.4	1.5	0.7	-0.3
Seeking ratio, punishment vs. effort	0.5	0.7	1.4	-0.9	-0.9	1.0	-0.8	1.2	0.9	-1.0	0.7	0.6	0.0	0.5
Retroperitoneal fat weight	5.9	25.3	33.3	5.8	5.7	-5.6	5.3	-5.3	-5.4	5.3	-5.3	-5.3	-3.2	1.0
Reaction time number correct	0.7	1.4	3.0	-0.8	-0.7	1.3	-1.7	0.5	1.5	-1.4	1.3	1.2	-0.5	-1.2
Reaction time mean minus median	0.6	1.6	2.2	-1.4	-1.4	1.2	-1.3	1.5	1.2	-1.1	1.4	1.5	-0.1	-1.2
Reaction time mean minus median AUC	0.5	1.3	2.6	-0.9	-1.0	1.0	-1.1	1.2	1.0	-0.9	1.3	1.3	-0.8	-1.6
Reaction time num false alarms	0.1	0.1	0.4	-0.2	-0.2	0.4	-0.2	0.4	0.4	-0.4	0.3	0.3	-0.2	-0.6
Reaction time num false alarms AUC	0.0	0.0	0.0	0.1	0.1	-0.0	0.1	-0.1	0.0	0.0	-0.2	-0.2	0.1	0.0
Reaction time trials correct on left	0.7	1.4	3.0	-0.8	-0.7	1.3	-1.7	0.5	1.5	-1.4	1.3	1.2	-0.5	-1.2
Reaction time trials on left	0.8	1.4	3.2	-0.8	-0.7	1.3	-1.8	0.5	1.5	-1.4	1.3	1.3	-0.4	-1.2
Reaction time mean	0.5	0.8	4.7	0.1	0.1	0.2	0.0	0.5	0.2	-0.2	0.6	0.7	-1.7	-2.2
Reaction time mean AUC	0.8	1.3	6.9	0.1	0.0	0.5	-0.2	0.7	0.4	-0.4	0.9	1.0	-2.1	-2.6
Median of all reaction times	0.7	1.0	4.9	0.7	0.7	-0.2	0.5	0.0	-0.2	0.2	0.2	0.3	-2.1	-2.2
Reaction time omissions	0.2	0.3	1.2	0.0	0.0	-0.3	-0.1	-1.1	-0.2	0.4	-0.5	-0.6	0.8	0.8
Reaction time false alarm rate	0.3	0.4	0.8	0.5	0.4	-0.6	0.9	-0.2	-0.7	0.7	-0.8	-0.8	0.2	0.5
Reaction time premature initiation rate	1.3	1.8	3.2	-1.5	-1.6	1.4	-1.1	1.8	1.3	-1.3	1.4	1.4	0.9	-0.0
Reaction time premature initiations	1.9	3.5	4.4	-2.0	-2.0	2.1	-2.0	2.1	2.0	-2.0	2.1	2.1	0.6	-0.6
Std. dev. reaction times	0.4	0.7	2.4	-0.5	-0.6	0.6	-0.7	0.7	0.6	-0.4	0.9	1.0	-0.8	-1.6
Reaction time trials completed	0.8	1.4	3.2	-0.8	-0.7	1.3	-1.8	0.5	1.5	-1.4	1.3	1.3	-0.4	-1.2
Reaction time trials AUC	0.8	1.4	3.1	-0.8	-0.7	1.3	-1.8	0.6	1.5	-1.5	1.3	1.3	-0.5	-1.2
Run reversals in cocaine runway, females	1.6	1.6	4.5	1.1	1.0	-1.3	0.7	-0.6	-1.2	1.3	-1.5	-1.5	0.7	2.1
Run reversals in cocaine runway, males	0.9	0.9	4.4	0.3	0.3	-0.7	0.5	-0.3	-0.7	0.7	-0.9	-0.9	1.5	2.1
Latency to leave start box in cocaine runway	0.9	1.0	4.5	0.4	0.4	0.3	-0.2	1.7	0.4	-0.5	0.7	0.7	-2.1	-1.4
Latency to leave start box in cocaine runway, F	1.4	1.5	4.2	-1.2	-1.2	1.3	-1.4	2.0	1.2	-1.2	1.2	1.2	0.5	0.5
Latency to leave start box in cocaine runway, M	4.1	3.8	16.8	2.2	2.1	-1.4	1.7	0.3	-1.1	1.0	-0.7	-0.6	-4.1	-2.9
Std. dev. time between licks in bursts	1.7	2.3	3.2	1.7	1.7	-1.7	1.7	-1.8	-1.6	1.6	-1.7	-1.7	-0.5	0.2
Total sessions with >9 infusions	1.6	1.9	4.2	-1.6	-1.5	1.4	-1.7	0.4	1.4	-1.3	1.0	0.9	2.0	1.3
Short access day 1 total inactive lever presses	0.2	0.2	1.5	-0.6	-0.7	0.1	-0.1	-0.1	-0.0	0.1	0.0	-0.0	1.2	0.4
Short access day 10 total inactive lever presses	0.1	0.2	0.4	0.3	0.2	-0.5	0.3	-0.3	-0.6	0.5	-0.5	-0.6	0.3	0.6
Short access day 1 total infusions	0.7	0.9	3.6	-1.0	-1.0	0.8	-0.8	-0.2	0.6	-0.6	0.2	0.1	1.9	1.5
Short access day 10 total infusions	0.4	0.5	1.5	-0.6	-0.5	0.6	-0.8	-0.1	0.7	-0.6	0.3	0.2	1.2	1.0
Short access total infusions	1.5	2.0	3.0	-1.6	-1.5	1.6	-1.6	0.7	1.5	-1.5	1.1	1.0	1.7	1.1
Short access day 1 locomotion	0.9	1.2	6.0	-1.0	-1.0	0.6	-0.8	-0.1	0.5	-0.4	0.2	0.1	2.4	1.9
Short access day 10 total locomotion	1.2	2.2	2.9	1.7	1.7	-1.7	1.5	-1.6	-1.6	1.6	-1.6	-1.6	-0.6	0.6
Short access total locomotion	0.3	0.4	0.5	0.7	0.7	-0.6	0.6	-0.7	-0.5	0.6	-0.6	-0.6	-0.1	0.6
One hour access (0.3 mA shock)	1.3	1.5	3.9	-1.4	-1.3	1.1	-1.7	0.4	1.2	-1.1	0.8	0.7	2.0	1.1
Compulsive drug intake	0.1	0.1	0.2	-0.2	-0.3	-0.2	0.4	-0.1	-0.4	0.4	-0.3	-0.3	0.3	0.2
One hour access (shock baseline)	0.8	1.2	2.7	-1.0	-0.9	1.1	-1.7	0.4	1.3	-1.2	0.9	0.8	1.6	0.7
Social response proportion	0.4	0.5	0.9	-0.9	-0.8	0.9	-0.9	0.3	0.9	-0.9	0.5	0.4	0.2	-0.0
Social responses	0.2	0.2	0.9	-0.5	-0.5	0.2	-0.2	-0.2	0.2	-0.0	-0.2	-0.2	0.9	0.9
Social time	0.1	0.1	0.2	0.1	0.2	0.2	-0.4	-0.4	0.3	-0.2	-0.1	-0.2	-0.5	0.1
Soleus weight	0.2	0.5	0.8	0.7	0.6	-0.8	0.9	-0.8	-0.8	0.8	-0.7	-0.7	-0.3	0.2
Bone: stiffness	2.6	4.2	5.4	-2.3	-2.3	2.3	-2.3	2.0	2.2	-2.2	2.3	2.3	0.6	-0.7
Tibialis anterior weight	0.1	0.4	0.6	-0.6	-0.7	0.7	-0.7	0.7	0.8	-0.7	0.7	0.7	0.4	0.0
Time to tail flick, vehicle, before self-admin	1.3	1.3	5.0	-1.0	-1.0	0.9	-0.9	0.2	0.8	-0.7	0.5	0.5	2.2	2.0
Time to tail flick, vehicle, after self-admin	1.3	1.7	5.3	1.5	1.6	-1.4	0.6	-2.3	-1.0	1.0	-1.2	-1.3	0.3	0.8
Time to tail flick, test, before self-admin	3.8	4.0	6.9	2.3	2.3	-2.1	2.0	-2.6	-1.9	1.9	-2.0	-2.0	-1.6	-0.2
Time to tail flick, test, after self-admin	0.2	0.2	0.4	0.6	0.7	-0.5	0.2	-0.5	-0.3	0.3	-0.5	-0.6	-0.2	0.4
Delta time to tail flick, vehicle, before/after SA	1.3	1.3	2.5	1.5	1.6	-1.5	0.5	-1.3	-0.9	1.0	-1.1	-1.1	-0.8	-0.4
Delta time to tail flick, test, before/after SA	1.5	1.5	2.4	-1.5	-1.5	1.3	-1.2	1.3	1.2	-1.1	0.9	0.9	1.6	0.8
Tibia length	0.0	0.1	0.3	-0.3	-0.3	0.2	-0.4	0.5	0.3	-0.1	0.3	0.3	0.4	-0.0
Ambulatory time before self-admin	1.9	2.8	6.7	1.6	1.6	-1.3	1.5	-2.2	-1.3	1.2	-1.0	-0.9	-2.6	-2.2
Ambulatory time after self-admin	0.4	0.5	3.2	0.4	0.4	-0.4	0.8	-1.8	-0.7	0.6	-0.6	-0.5	-0.3	-0.3
Bone: tissue strength	0.3	0.3	0.7	-0.3	-0.3	0.6	-0.1	0.6	0.4	-0.6	0.5	0.5	-0.9	-0.6
Total heroin consumption	0.9	1.0	1.7	-0.7	-0.6	1.2	-0.9	0.9	1.1	-1.2	1.2	1.2	-0.7	-1.3
Bone: trabecular number	0.2	0.3	0.6	0.6	0.6	-0.7	0.7	-0.3	-0.8	0.7	-0.5	-0.5	-0.2	0.2
Bone: trabecular spacing	0.3	0.3	1.3	0.7	0.7	-0.4	0.3	-0.5	-0.2	0.2	-0.4	-0.5	-1.1	-0.7
Bone: trabecular thickness	0.7	0.9	1.5	-1.2	-1.2	0.9	-0.8	1.1	0.7	-0.7	1.0	1.0	1.1	0.3
Bone: trabecular tissue density	0.6	0.9	1.4	-1.1	-1.1	1.1	-0.9	1.2	0.9	-1.0	1.1	1.1	0.3	-0.7
Water consumed over 24 hours	0.3	0.4	0.7	0.5	0.5	-0.6	0.6	-0.8	-0.6	0.6	-0.8	-0.8	-0.1	0.8
Number of responses in last shaping day	0.6	0.7	1.1	-0.5	-0.5	0.8	-0.7	1.1	0.9	-0.9	1.0	1.1	-0.4	-0.7