Ffar4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Ffar4 0.23 0.06 0.0e+00 0.29 0.29 0.29 0.29 5.0e-32 2.0e-32 1.7e-32 4.4e-32
2 NAcc gene expression Ffar4 0.33 0.08 0.0e+00 0.47 0.45 0.46 0.47 8.1e-62 9.7e-58 1.6e-59 7.2e-61
3 Brain gene expression Ffar4 0.12 0.04 5.6e-17 0.16 0.18 0.18 0.19 2.1e-14 2.9e-16 2.1e-16 3.0e-17
4 BLA mRNA stability Ffar4 0.09 0.05 3.5e-04 0.12 0.07 0.12 0.1 5.4e-07 1.2e-04 7.4e-07 4.3e-06
5 BLA gene expression Ffar4 0.29 0.09 1.6e-15 0.27 0.27 0.25 0.29 5.6e-15 1.1e-14 1.3e-13 9.6e-16
6 PL gene expression Ffar4 0.21 0.07 5.6e-17 0.14 0.17 0.15 0.14 9.7e-15 2.6e-18 1.4e-16 1.1e-15
7 Adipose mRNA stability Ffar4 0.18 0.08 8.1e-11 0.08 0.09 0.09 0.07 2.0e-09 2.1e-10 7.3e-10 1.1e-08
8 OFC gene expression Ffar4 0.14 0.09 4.8e-03 0.07 0.02 -0.01 0.01 7.8e-03 1.1e-01 5.0e-01 2.0e-01
9 IL gene expression Ffar4 0.21 0.1 6.0e-05 0.15 0.1 0.14 0.15 1.8e-04 2.3e-03 2.7e-04 1.9e-04
10 Adipose gene expression Ffar4 0.39 0.09 0.0e+00 0.22 0.21 0.21 0.22 5.5e-24 3.2e-23 1.8e-22 1.5e-23

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density3.76.210.83.32.8-2.7-2.7-2.7-2.72.21.91.2-1.9
Area under the delay curve0.30.31.1-0.3-0.30.3-0.00.40.5-0.1-0.6-1.0-1.1
BMI with tail0.61.83.41.01.4-0.7-1.2-1.8-1.71.90.71.2-1.4
BMI without tail1.42.85.61.71.7-1.1-1.7-1.8-1.72.41.51.8-1.1
Body weight0.21.02.50.81.0-1.3-1.2-0.7-0.30.61.51.60.4
Weight adjusted by age0.70.84.40.40.30.0-0.5-0.5-0.11.2-1.0-0.2-2.1
Bone surface2.95.19.63.12.5-2.7-2.4-2.3-2.32.21.91.6-1.1
Bone volume3.05.08.32.92.5-2.7-2.6-2.2-2.12.02.11.8-1.1
Breakpoint value in progressive ratio session0.40.41.5-0.6-0.5-0.20.30.80.9-1.20.1-0.7-0.1
Number of licking bursts1.11.33.7-0.9-0.91.00.70.80.2-0.4-1.5-1.9-1.7
Context. condit. distance diff. score1.21.43.21.11.3-1.8-1.8-1.3-1.40.31.10.5-0.1
Locomotion velocity, session 11.51.66.3-0.6-1.31.51.11.10.3-0.6-1.6-2.5-0.8
Locomotion distance, session 10.70.92.3-0.8-1.00.81.00.80.5-0.9-1.1-1.5-0.6
Locomotion velocity, session 21.01.23.21.50.9-0.7-1.1-0.9-1.80.60.6-1.4-0.5
Locomotion distance, session 20.10.20.80.2-0.1-0.30.10.2-0.4-0.50.1-0.9-0.3
Locomotion velocity, session 30.30.40.80.70.7-0.6-0.8-0.5-0.60.00.9-0.10.4
Locomotion distance, session 30.60.62.40.40.5-0.9-0.3-0.4-0.5-0.41.30.61.5
Stereotopy head waving bouts, day 30.50.51.50.70.60.0-0.8-0.8-1.00.8-0.4-0.4-1.2
Stereotopy head waving duration, day 30.70.82.90.70.6-0.1-0.8-0.8-0.81.2-0.5-0.5-1.7
Locomotion velocity, session 72.62.85.21.61.8-2.3-1.9-1.7-1.41.72.01.1-0.2
Locomotion distance, session 71.72.14.41.61.5-2.1-1.5-1.3-1.01.41.91.30.5
Stereotopy head waving bouts, day 70.60.72.90.60.40.2-0.6-0.6-1.00.2-0.6-1.7-1.1
Stereotopy head waving duration, day 70.30.40.80.70.50.3-0.7-0.6-0.80.5-0.2-0.9-0.6
Locomotion velocity, session 80.20.30.60.70.6-0.6-0.6-0.8-0.70.40.3-0.2-0.1
Locomotion distance, session 80.71.02.41.01.0-1.4-1.3-1.1-1.60.00.7-0.3-0.6
Degree of sensitization distance0.30.31.20.40.4-0.7-0.7-0.3-0.10.80.1-0.2-1.1
Degree of sensitization stereotypy0.40.42.60.1-0.10.60.20.1-0.3-0.7-0.7-1.6-0.0
Conditioned locomotion0.30.42.5-0.20.2-0.1-0.5-0.20.40.30.71.60.4
Cocaine response after cond. corrected0.20.20.3-0.1-0.60.10.40.60.4-0.3-0.6-0.40.5
Cocaine response after cond. not corrected0.20.20.50.1-0.4-0.10.10.40.3-0.4-0.4-0.70.6
Cocaine response before conditioning0.10.11.10.30.2-0.1-0.3-0.1-0.2-0.2-0.1-1.0-0.2
Saline control response2.43.25.6-2.4-1.61.71.51.72.1-2.2-1.7-1.8-0.2
Bone: connectivity density5.48.513.93.73.3-2.8-2.9-3.3-3.43.12.21.8-2.1
Bone: cortical apparent density0.91.23.1-0.8-0.91.41.20.30.3-0.1-1.8-1.6-0.8
Bone: cortical area0.71.12.51.00.7-1.6-0.9-0.30.1-0.11.51.51.2
Bone: cortical porosity0.91.02.00.91.0-0.9-1.2-1.0-1.21.0-0.0-0.8-1.4
Bone: cortical porosity1.11.22.01.31.3-1.3-1.4-1.1-1.41.00.6-0.4-0.7
Bone: cortical thickness1.32.13.7-1.3-1.61.11.41.81.8-1.9-1.0-1.01.2
Bone: cortical thickness1.72.03.8-1.3-1.61.41.31.41.2-1.4-1.8-2.0-0.1
Bone: cortical tissue density0.91.13.2-0.7-0.81.41.20.20.20.1-1.8-1.6-1.0
Condit. Reinf. active minus inactive responses0.10.20.6-0.2-0.2-0.10.50.5-0.1-0.30.4-0.30.8
Condit. Reinf. active-inactive response ratio0.10.10.6-0.2-0.30.20.60.40.0-0.10.10.20.8
Condit. Reinf. active responses0.20.30.9-0.5-0.2-0.20.50.70.4-0.60.5-0.30.9
Condit. Reinf. inactive responses0.10.20.6-0.4-0.20.00.20.40.5-0.5-0.1-0.80.0
Incentive salience index mean0.81.01.7-1.0-1.00.41.21.30.9-1.3-0.2-0.71.2
Condit. Reinf. lever presses2.43.24.7-2.2-1.91.52.12.02.0-2.0-1.4-1.11.1
Condit. Reinf. active minus inactive responses2.32.84.11.61.8-1.9-2.0-1.8-1.71.81.41.8-0.8
Condit. Reinf. active-inactive response ratio1.71.72.71.21.2-1.2-1.5-1.5-1.51.70.51.3-1.2
Condit. Reinf. active responses0.40.52.00.50.6-0.8-0.9-0.5-0.10.30.91.40.2
Condit. Reinf. inactive responses1.21.53.3-1.1-1.20.81.11.41.8-1.7-0.2-0.11.6
Condit. Reinf. lever presses0.20.30.5-0.3-0.70.70.40.50.7-0.6-0.6-0.50.2
Condit. Reinf. lever reinforcers received0.20.20.90.20.4-0.5-0.6-0.30.10.10.61.00.0
Conditioned reinforcement - actives0.80.81.61.30.9-0.9-1.1-0.6-1.0-0.21.0-0.80.5
Conditioned reinforcement - inactives2.83.16.72.42.1-2.3-1.7-1.7-2.60.91.1-1.2-0.2
Conditioned locomotion0.20.21.00.30.1-0.20.10.3-0.0-0.3-0.9-1.00.4
Patch foraging indifference point 0 sec0.60.91.8-0.7-1.00.91.01.41.1-1.2-0.4-0.60.8
Patch foraging indifference point AUC3.94.56.7-2.2-2.51.71.72.62.2-2.5-1.8-2.60.6
Delay disc. indifference point, 0s delay1.71.84.41.11.7-1.1-2.1-1.4-1.41.50.60.4-1.4
Delay disc. indifference point, 16s delay0.30.30.8-0.4-0.40.30.20.80.6-0.8-0.4-0.9-0.6
Delay disc. indifference point, 2s delay0.50.63.20.40.10.0-0.4-0.5-0.31.1-0.90.4-1.8
Delay disc. indifference point, 24s delay1.11.12.2-1.1-1.20.80.61.31.0-1.3-0.6-1.50.4
Delay disc. indifference point, 4s delay0.40.41.6-0.2-0.20.30.30.30.2-0.3-0.8-1.3-1.1
Delay disc. indifference point, 8s delay1.51.52.7-1.2-1.31.30.81.31.6-0.5-1.3-1.6-1.0
Indifference point function ln k3.95.57.92.62.7-2.2-2.1-2.7-2.52.42.22.8-0.3
Indifference point function log k3.95.57.92.62.7-2.2-2.1-2.7-2.52.42.22.8-0.3
Patch foraging total patch changes 0 sec0.50.81.7-0.6-0.90.90.91.31.2-1.1-0.3-0.40.8
Patch foraging total patch changes 12 sec3.84.97.7-2.3-2.42.52.22.52.2-2.0-2.2-2.80.2
Patch foraging total patch changes 18 sec0.70.82.1-0.7-1.01.20.51.10.7-0.7-0.9-1.4-0.7
Patch foraging total patch changes 24 sec0.70.91.9-0.8-0.90.40.61.41.3-1.30.2-0.51.0
Patch foraging total patch changes 6 sec3.45.17.5-2.0-2.52.22.42.72.3-2.6-1.8-2.41.3
Patch foraging time to switch 0 sec0.61.02.9-1.0-1.11.10.90.70.5-0.5-1.7-1.1-0.8
Patch foraging water rate 0 sec0.91.52.21.41.5-1.4-1.3-1.2-1.11.01.50.90.6
Patch foraging water rate 12 sec0.50.81.50.90.9-1.0-1.1-0.6-0.70.41.20.61.2
Patch foraging water rate 18 sec1.41.93.51.51.6-1.7-1.6-1.1-1.20.81.91.20.7
Patch foraging water rate 24 sec0.60.81.41.01.2-1.2-1.0-0.8-0.60.40.91.00.4
Patch foraging water rate 6 sec0.10.10.20.40.4-0.2-0.3-0.3-0.30.5-0.00.20.1
Seeking ratio, delayed vs. immediate footshock0.20.31.2-0.4-0.30.1-0.10.60.4-1.1-0.10.60.5
Distance traveled before self-admin1.21.33.71.11.3-1.3-0.9-1.0-1.40.61.90.7-0.1
Distance traveled after self-admin4.04.56.92.12.2-2.3-1.9-2.3-2.62.31.71.3-2.2
Extensor digitorum longus weight0.20.61.70.10.8-1.3-0.9-0.5-0.3-0.01.11.10.3
Bone: elastic displacement0.81.04.00.10.50.70.1-0.9-0.81.8-0.7-0.2-2.0
Bone: elastic work1.41.85.21.11.2-0.3-0.9-1.6-1.52.30.0-0.2-2.1
Bone: endosteal estimation4.59.717.53.73.3-4.2-3.6-2.9-2.42.63.63.0-0.1
Bone: endosteal perimeter4.59.314.83.63.2-3.9-3.5-2.9-2.62.53.33.1-0.5
Epididymis fat weight0.61.46.20.61.0-1.1-1.1-1.1-0.31.50.92.5-0.4
Delta time in closed arm before/after self-admin0.80.82.0-0.7-1.0-0.00.91.21.0-1.1-0.1-0.11.4
Delta time in open arm before/after self-admin1.71.62.71.31.5-0.9-1.6-1.5-1.61.30.80.1-1.2
Diff in mean of infusions in LGA sessions1.61.82.91.61.6-1.7-1.6-1.3-1.21.41.40.90.0
Delay discount exponential model param0.30.41.10.30.4-0.4-0.1-0.5-0.50.30.71.01.0
Extinction: sum of active levers before priming0.30.30.9-0.2-0.2-0.7-0.40.50.2-0.80.90.60.6
Active lever presses in extinction session 63.53.46.11.92.0-2.5-2.0-1.9-2.01.41.60.4-2.0
Bone: final force0.20.31.20.5-0.1-0.8-0.30.40.4-0.70.60.11.1
Bone: final moment0.20.31.00.5-0.1-0.7-0.20.40.5-0.50.60.31.0
Food consumed during 24 hour testing period0.20.31.3-0.1-0.40.10.40.70.2-0.4-0.1-0.71.2
Glucose0.20.21.80.0-0.0-0.30.20.10.3-0.20.50.21.3
Heart weight0.71.03.2-0.6-1.00.90.81.51.2-0.70.0-0.01.8
Delay discount hyperbolic model param0.30.31.30.20.3-0.30.0-0.3-0.4-0.00.70.81.1
Intermittent access intake day 1-15 change3.53.45.32.22.2-1.9-2.3-1.8-2.01.22.31.30.3
Intermittent access intake escalation3.03.04.82.11.9-1.7-2.2-1.5-1.81.12.11.50.6
Intermittent access intake escalation 24.74.77.32.62.5-2.0-2.7-2.2-2.61.72.51.40.1
Intermitt. access day 1 inactive lever presses0.20.20.80.60.5-0.4-0.5-0.5-0.50.9-0.20.1-0.5
Intermitt. access day 15 inactive lever presses0.40.40.70.80.8-0.6-0.5-0.6-0.50.9-0.3-0.4-0.6
Intermitt. access escalation Index1.51.32.70.91.5-0.5-0.9-1.6-0.61.71.41.30.2
Intermittent access day 1 total infusions0.30.30.80.70.9-0.90.2-0.6-0.70.4-0.0-0.10.1
Intermittent access day 15 total infusions2.02.23.71.91.9-1.7-1.3-1.4-1.50.81.61.31.3
Intermittent access terminal intake (last 3 days)1.92.04.11.82.0-1.6-1.5-1.5-1.81.11.00.60.6
Intermittent access total infusions0.91.02.41.31.5-1.2-0.7-1.2-1.40.80.40.50.5
Intermittent access day 1 locomotion0.10.10.60.1-0.0-0.40.50.20.1-0.0-0.30.20.8
Intermittent access day 15 total locomotion0.60.71.6-0.3-0.40.21.10.80.4-1.2-1.0-1.20.4
Intermittent access total locomotion0.30.31.2-0.2-0.1-0.10.60.4-0.0-0.6-1.1-1.0-0.1
Intermittent access standard deviation3.23.45.72.22.1-2.0-2.1-1.7-1.91.42.41.21.0
Left kidney weight0.41.25.2-0.7-0.90.40.51.21.2-1.50.30.12.3
Right kidney weight1.54.17.9-1.9-2.11.31.92.62.4-2.7-0.3-0.32.8
Cocaine induced anxiety0.40.51.10.60.9-0.5-0.5-0.9-0.71.1-0.10.4-0.6
Post-drug Anxiety0.80.92.7-0.9-0.61.10.70.41.00.2-1.6-0.3-1.4
Baseline Anxiety1.01.02.4-1.3-1.30.90.71.21.5-0.8-0.6-0.9-0.2
Tail length0.31.03.00.60.4-1.5-0.70.30.4-0.31.71.21.6
Length with tail0.41.34.3-0.2-0.5-0.80.01.31.5-1.70.80.32.1
Length without tail0.61.45.2-0.9-0.8-0.30.41.41.3-2.3-0.0-0.51.9
Times rat made contact with spout0.91.02.51.01.1-0.6-1.2-0.9-0.81.40.2-0.3-1.6
Lifetime Intake0.40.41.10.81.1-0.7-0.1-0.8-1.00.3-0.20.00.1
Liver weight, left0.61.04.4-0.3-0.1-0.70.10.61.1-1.11.10.72.1
Liver weight, right0.40.72.6-0.6-0.3-0.4-0.20.51.2-0.80.70.61.6
Locomotor activity0.30.51.00.90.9-0.4-0.6-0.7-1.00.80.20.2-0.9
Locomotor testing distance0.40.71.61.31.1-0.6-0.6-0.8-1.20.80.30.0-0.8
Locomotor testing rearing1.11.62.91.51.6-1.5-1.4-1.3-1.70.61.20.6-0.8
Locomotion in novel chamber3.03.77.42.12.1-1.9-2.5-2.1-2.71.61.20.9-1.5
Locomotion in novel chamber post-restriction0.40.43.1-0.3-0.5-0.20.00.4-0.0-1.7-0.4-0.7-0.1
Fecal boli incidents, locomotor time 11.01.11.71.01.3-1.0-1.1-1.2-1.31.00.70.4-1.1
Change in fecal boli incidents, locomotor task1.11.12.0-1.1-1.11.00.91.31.0-1.4-0.8-0.80.8
Time >=10cm from walls, locomotor time 12.12.110.7-0.0-0.0-0.9-0.00.60.4-1.82.4-0.23.3
Bouts of movement, locomotor time 10.20.20.60.20.4-0.0-0.80.0-0.1-0.40.0-0.6-0.8
Total resting periods, locomotor time 10.30.31.50.00.30.0-0.80.20.0-0.70.0-1.2-0.8
Rest time, locomotor task time 11.51.64.91.11.5-0.6-1.8-1.0-1.10.80.8-0.9-2.2
Distance moved, locomotor task time 11.41.65.2-1.2-1.40.21.41.41.2-1.2-0.20.32.3
Vertical activity count, locomotor time 11.21.35.9-0.7-1.30.41.01.21.2-0.80.10.72.4
Time >=10cm from walls, locomotor time 20.80.83.70.60.8-1.0-0.6-0.3-0.3-0.21.9-0.31.3
Bouts of movement, locomotor time 21.21.34.6-0.7-1.01.30.61.00.3-0.9-1.6-2.1-1.0
Total resting periods, locomotor time 21.21.35.4-0.6-0.91.20.41.00.3-1.1-1.3-2.3-0.9
Rest time, locomotor task time 20.50.52.2-0.2-0.30.3-0.40.40.2-1.20.6-1.5-0.9
Distance moved, locomotor task time 20.50.62.30.10.4-0.9-0.3-0.2-0.10.61.00.91.5
Vertical activity count, locomotor time 20.50.51.50.50.5-0.8-0.3-0.3-0.11.20.60.81.2
Light reinforcement 10.20.32.1-0.4-0.30.40.20.10.1-0.2-0.5-0.7-1.5
Light reinforcement 21.01.33.9-0.9-0.91.30.80.10.30.4-1.5-1.7-2.0
Bone: marrow area4.69.917.53.73.4-4.2-3.6-2.9-2.52.73.53.0-0.2
Bone: maximum diameter5.39.715.53.83.4-3.9-3.7-3.1-2.72.33.23.1-0.6
Bone: maximum force0.61.02.81.50.9-1.7-1.2-0.6-0.70.31.10.40.3
Bone: maximum moment0.50.92.41.40.8-1.6-1.0-0.6-0.50.51.20.70.2
Mean time between licks in bursts0.30.51.8-0.4-0.40.80.60.70.8-0.3-0.00.61.3
Mean num. licks in bursts2.02.43.91.61.7-1.6-1.6-1.5-0.91.61.82.00.6
Cd content in liver1.41.63.2-1.1-1.41.31.51.81.5-1.0-0.8-0.31.1
Co content in liver0.30.41.2-0.5-0.61.10.70.30.80.7-0.70.4-0.2
Cu content in liver3.84.68.7-1.8-2.22.42.41.92.0-1.4-2.8-2.9-0.8
Fe content in liver1.51.83.4-1.5-1.51.91.61.30.8-1.0-1.6-1.20.1
K content in liver0.20.20.6-0.6-0.00.2-0.20.0-0.0-0.5-0.5-0.8-0.6
Mg content in liver0.60.71.3-1.0-0.70.80.60.70.5-1.0-0.9-1.1-0.2
Mn content in liver2.42.88.7-1.4-1.61.51.41.10.8-1.4-2.4-2.9-0.7
Na content in liver1.61.73.4-1.5-1.21.41.21.00.6-1.3-1.8-1.9-0.5
Rb content in liver0.10.10.50.30.4-0.7-0.5-0.20.00.10.6-0.20.2
Se content in liver14.617.926.9-4.2-4.84.94.84.23.6-3.3-5.2-4.8-0.3
Sr content in liver0.10.10.20.20.00.1-0.20.2-0.10.00.0-0.50.5
Zn content in liver1.21.32.3-1.5-1.31.51.21.00.9-0.4-1.3-1.2-0.1
Bone: minimum diameter6.011.218.53.83.4-4.3-3.5-2.9-2.52.34.24.01.1
Time in familiar zone, hab. session 10.70.62.30.70.4-0.3-0.2-0.7-0.71.3-0.50.7-1.5
Time in novel zone, hab. session 10.30.30.7-0.5-0.50.40.40.60.5-0.80.1-0.80.7
Total zone transitions, hab. session 10.00.10.3-0.0-0.0-0.10.00.1-0.1-0.4-0.1-0.6-0.4
Total locomotion distance, hab. session 10.91.22.1-1.3-1.11.01.31.00.8-1.2-1.1-1.4-0.5
Locomotion velocity, hab. session 11.72.53.5-1.9-1.71.41.71.61.3-1.8-1.5-1.9-0.2
Time in familiar zone, hab. session 20.10.20.6-0.1-0.30.30.30.20.40.5-0.30.8-0.3
Time in novel zone, hab. session 20.10.10.7-0.1-0.10.20.20.1-0.0-0.50.0-0.80.4
Total zone transitions, hab. session 20.71.01.8-1.2-1.20.90.81.20.9-1.3-0.7-0.80.2
Total locomotion distance, hab. session 20.91.22.2-1.5-1.40.91.11.31.0-1.3-0.9-0.90.0
Locomotion velocity, hab. session 21.11.42.6-1.6-1.40.91.11.31.0-1.5-1.1-1.1-0.2
Novel to familiar place preference ratio4.34.57.72.62.2-2.1-2.4-2.3-2.82.01.3-0.6-1.8
Novelty place preference4.74.78.02.72.3-2.2-2.5-2.4-2.82.01.3-0.6-1.9
Time in novel zone, NPP test4.84.98.32.72.3-2.3-2.5-2.4-2.92.11.5-0.5-1.8
Total zone transitions, NPP test1.11.62.8-1.6-1.50.81.11.51.4-1.7-0.5-0.80.9
Total locomotion distance, NPP test1.82.53.7-1.9-1.91.31.51.71.5-1.8-1.4-1.80.3
Locomotion velocity, NPP test1.82.53.9-2.0-1.91.21.51.81.6-1.9-1.3-1.70.5
Intraocular pressure0.30.31.2-0.3-0.60.50.40.60.2-0.2-0.9-0.3-1.1
Delta distance traveled before/after self-admin1.71.93.61.21.3-1.3-1.5-1.5-1.21.90.41.2-1.7
Delta ambulatory time before/after self-admin2.42.64.51.61.7-1.7-1.8-1.9-1.52.10.71.3-1.5
Parametrial fat weight0.50.93.5-0.9-0.40.60.31.01.4-0.90.40.71.9
Pavlov. Cond. lever latency0.10.10.40.2-0.10.50.1-0.10.10.4-0.50.6-0.5
Pavlov. Cond. magazine entry latency0.91.23.8-0.8-1.10.41.21.51.0-1.2-0.2-0.72.0
Pavlov. Cond. change in total contacts0.30.32.6-0.0-0.2-0.10.40.5-0.0-0.20.5-0.11.6
Pavlov. Cond. index score0.60.72.0-0.7-0.70.10.71.00.6-1.2-0.1-0.91.4
Pavlov. Cond. latency score0.50.61.6-0.7-0.6-0.00.60.90.6-1.20.1-0.81.3
Pavlov. Cond. lever contacts0.80.92.0-1.1-0.80.20.81.11.0-1.4-0.2-1.01.2
Pavlov. Cond. magazine entry number0.30.42.50.10.40.2-0.6-0.7-0.40.3-0.2-0.1-1.6
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.2-0.10.1-0.10.20.3-0.30.0-0.20.0
Pavlov. Cond. lever-magazine prob. diff.0.60.72.0-0.8-0.70.20.81.00.6-1.1-0.1-0.91.4
Pavlov. Cond. response bias0.60.73.3-0.5-0.70.10.81.00.7-0.80.2-0.41.8
Pavlov. Cond. lever latency1.52.03.91.11.6-1.2-1.5-1.7-2.01.31.21.1-1.0
Pavlov. Cond. magazine entry latency0.20.32.0-0.0-0.1-0.20.20.50.3-0.00.6-0.11.4
Pavlov. Cond. change in total contacts0.50.71.6-0.8-0.90.50.71.11.3-0.8-0.4-0.40.9
Pavlov. Cond. index score0.81.01.9-0.7-1.00.50.91.31.4-1.0-0.4-0.81.4
Pavlov. Cond. latency score0.60.71.9-0.5-0.80.30.61.11.1-0.8-0.2-0.81.4
Pavlov. Cond. lever contacts1.21.73.8-1.1-1.51.11.31.62.0-1.4-0.9-0.80.9
Pavlov. Cond. magazine entry number1.92.44.11.51.5-1.1-1.6-2.0-1.81.50.61.3-2.0
Pavlov. Cond. intertrial magazine entries1.01.42.11.11.2-1.1-1.1-1.4-1.41.00.81.0-1.2
Pavlov. Cond. lever-magazine prob. diff.0.60.71.7-0.5-0.90.30.71.11.1-0.8-0.2-0.91.3
Pavlov. Cond. response bias1.21.63.1-1.1-1.40.91.31.71.8-1.3-0.6-0.91.3
Time in closed arm before self-admin2.52.84.51.71.7-1.3-1.8-1.8-2.11.91.50.2-1.8
Time in closed arm after self-admin0.10.20.5-0.3-0.2-0.30.10.50.1-0.50.7-0.2-0.5
Time in open arm before self-admin0.30.41.4-0.6-0.60.50.70.50.8-0.1-1.20.4-0.0
Time in open arm after self-admin0.20.20.30.60.5-0.3-0.6-0.6-0.60.40.1-0.0-0.5
Bone: periosteal estimation2.75.611.82.92.5-3.4-2.8-2.0-1.51.52.82.40.3
Bone: periosteal perimeter3.25.39.42.62.4-3.1-2.7-2.1-1.81.52.62.6-0.2
Bone: post-yield work0.81.12.81.50.9-1.7-1.0-0.6-1.10.21.41.00.4
Progressive ratio test 1 active lever presses0.50.50.90.81.0-0.8-0.4-0.9-0.90.70.0-0.0-0.7
Progressive ratio test 1 breakpoint0.50.61.10.81.0-0.8-0.6-0.9-0.90.80.1-0.0-0.8
Progressive ratio test 1 inactive lever presses2.52.74.71.82.1-2.2-1.6-1.9-1.81.81.10.3-1.1
Progressive ratio test 2 active lever presses1.61.83.91.82.0-1.7-1.1-1.3-1.70.71.2-0.2-0.3
Progressive ratio test 2 breakpoint2.12.45.22.02.3-2.0-1.5-1.6-1.81.01.2-0.4-0.5
Progressive ratio test 2 inactive lever presses1.82.04.31.71.9-1.6-1.0-1.6-2.11.10.2-0.8-1.2
Incentive Sensitization - Responses3.53.56.32.42.5-2.1-2.1-1.9-2.21.51.8-0.1-0.3
Incentive Sensitization - Breakpoint3.13.15.62.32.4-2.0-2.0-1.8-2.01.31.8-0.2-0.2
Sum of active levers in priming session hrs 5-60.20.20.90.40.2-0.1-0.4-0.2-0.21.0-0.40.3-0.7
Progressive ratio0.30.41.1-0.7-0.30.30.50.50.9-0.60.11.10.5
Food seeking constrained by brief footshock0.91.14.30.3-0.0-0.80.50.9-0.1-2.11.0-0.41.8
Seeking ratio, punishment vs. effort0.40.41.50.70.0-0.8-0.20.4-0.5-0.80.6-1.20.7
Retroperitoneal fat weight0.10.41.4-0.8-0.1-0.00.40.41.00.10.31.20.6
Reaction time number correct2.23.24.92.02.1-1.8-2.2-2.0-1.61.91.51.5-1.0
Reaction time mean minus median0.40.63.30.50.2-0.30.40.1-0.20.40.90.91.8
Reaction time mean minus median AUC0.30.41.80.30.10.10.40.1-0.00.60.51.11.3
Reaction time num false alarms0.40.51.8-0.7-0.6-0.10.10.81.0-1.30.10.70.8
Reaction time num false alarms AUC0.50.61.6-0.6-0.7-0.10.10.81.1-1.30.10.81.1
Reaction time trials correct on left2.23.24.92.02.1-1.8-2.2-2.0-1.61.91.51.5-1.0
Reaction time trials on left2.23.14.62.02.1-1.8-2.1-1.9-1.51.81.51.5-0.9
Reaction time mean0.91.33.5-1.2-1.21.01.31.31.0-0.8-0.2-0.21.9
Reaction time mean AUC1.31.83.5-1.4-1.51.31.61.51.2-1.0-0.6-0.31.9
Median of all reaction times0.91.32.0-1.4-1.31.21.21.41.1-0.9-0.4-0.31.4
Reaction time omissions1.01.34.70.60.8-0.8-0.5-0.3-0.30.81.61.92.2
Reaction time false alarm rate1.41.94.5-1.5-1.60.71.11.71.7-2.1-0.6-0.01.3
Reaction time premature initiation rate1.01.43.6-1.1-1.10.50.81.21.6-1.6-0.3-0.61.9
Reaction time premature initiations0.30.42.20.00.1-0.4-0.40.10.7-0.60.60.31.5
Std. dev. reaction times0.71.06.4-0.3-0.50.31.00.90.7-0.10.60.92.5
Reaction time trials completed2.23.14.62.02.1-1.8-2.1-1.9-1.51.81.51.5-0.9
Reaction time trials AUC2.02.84.41.92.0-1.7-2.1-1.9-1.51.81.41.4-0.9
Run reversals in cocaine runway, females0.30.31.40.2-0.30.2-0.20.2-0.20.4-0.6-0.7-1.2
Run reversals in cocaine runway, males3.63.55.7-1.8-2.02.12.41.81.6-2.3-1.5-1.61.0
Latency to leave start box in cocaine runway2.32.55.11.31.7-1.5-1.7-1.8-1.61.61.32.3-0.6
Latency to leave start box in cocaine runway, F3.53.95.11.82.2-1.8-2.1-2.3-2.32.01.72.2-1.0
Latency to leave start box in cocaine runway, M0.20.21.30.20.1-0.4-0.5-0.20.10.30.31.20.3
Std. dev. time between licks in bursts2.12.54.3-2.0-1.72.11.71.72.0-1.0-1.6-0.30.4
Total sessions with >9 infusions0.30.31.0-0.3-0.30.20.40.5-0.1-0.8-1.0-0.9-0.6
Short access day 1 total inactive lever presses3.03.47.51.61.9-0.8-0.6-2.3-2.32.6-1.20.7-2.7
Short access day 10 total inactive lever presses0.30.31.40.10.50.2-0.6-0.4-0.01.2-0.5-0.3-0.8
Short access day 1 total infusions0.70.72.8-0.8-0.40.70.90.40.2-0.5-1.7-1.0-0.7
Short access day 10 total infusions0.50.51.5-0.7-0.40.51.20.70.6-0.6-1.1-0.50.7
Short access total infusions0.20.20.5-0.10.3-0.10.6-0.1-0.4-0.4-0.7-0.6-0.4
Short access day 1 locomotion0.20.21.3-0.10.10.0-0.4-0.2-0.30.1-0.7-0.5-1.1
Short access day 10 total locomotion0.10.10.5-0.1-0.2-0.00.10.1-0.10.3-0.7-0.5-0.1
Short access total locomotion0.30.31.1-0.5-0.30.40.40.30.1-0.1-1.1-0.9-0.9
One hour access (0.3 mA shock)4.75.59.53.13.0-2.7-2.6-2.5-2.71.62.40.40.1
Compulsive drug intake3.13.27.21.72.0-1.7-2.1-2.0-1.11.72.71.20.8
One hour access (shock baseline)0.50.61.41.21.1-1.0-0.7-0.6-1.10.30.30.30.1
Social response proportion2.83.05.41.92.0-1.5-1.5-2.2-2.02.30.71.0-1.6
Social responses0.40.51.10.90.7-0.7-0.2-1.1-0.70.80.20.5-0.7
Social time0.70.91.8-0.9-1.01.01.30.91.1-1.0-0.8-0.30.7
Soleus weight1.02.94.81.71.8-2.2-2.1-1.6-1.11.71.91.6-0.4
Bone: stiffness0.71.23.51.21.0-1.9-1.4-0.5-0.5-0.21.50.80.7
Tibialis anterior weight0.51.63.90.81.6-2.0-1.6-1.2-1.00.61.60.9-0.4
Time to tail flick, vehicle, before self-admin0.90.94.6-0.4-0.20.90.3-0.20.00.6-1.5-0.8-2.1
Time to tail flick, vehicle, after self-admin0.60.62.60.50.7-1.6-0.9-0.2-0.3-0.01.40.4-0.1
Time to tail flick, test, before self-admin2.42.35.41.61.6-2.3-1.6-1.5-1.80.81.80.3-0.8
Time to tail flick, test, after self-admin2.02.15.01.51.5-1.2-1.4-1.6-1.02.20.70.8-1.7
Delta time to tail flick, vehicle, before/after SA1.81.85.41.11.1-2.3-1.4-0.6-0.8-0.22.21.01.1
Delta time to tail flick, test, before/after SA0.20.20.60.30.30.2-0.5-0.40.10.8-0.10.3-0.6
Tibia length0.20.41.3-0.3-0.50.10.30.91.0-0.80.0-0.11.1
Ambulatory time before self-admin0.90.92.30.91.0-1.0-0.9-0.9-1.30.61.50.7-0.4
Ambulatory time after self-admin6.87.512.82.82.9-3.0-2.6-3.1-3.62.92.01.3-2.6
Bone: tissue strength0.10.10.20.00.1-0.10.00.10.30.30.40.30.4
Total heroin consumption0.20.20.7-0.4-0.4-0.10.30.70.5-0.8-0.3-0.50.0
Bone: trabecular number3.35.110.43.22.5-2.3-2.3-2.5-2.62.31.81.2-1.4
Bone: trabecular spacing1.82.34.1-2.0-1.71.71.41.71.9-1.3-0.8-0.41.6
Bone: trabecular thickness2.52.94.72.22.0-1.8-2.0-1.8-1.71.51.81.3-0.7
Bone: trabecular tissue density0.50.81.41.01.0-1.0-1.2-1.0-0.70.60.80.7-0.6
Water consumed over 24 hours1.31.62.71.31.5-1.3-1.4-1.3-1.61.40.7-0.2-1.3
Number of responses in last shaping day0.30.31.20.10.50.3-0.2-0.7-0.30.6-1.10.2-0.7