Hub : Genes

Ffar4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA mRNA stability Ffar4 0.09 0.05 2.0e-04 0.08 0.07 0.05 0.08 3.3e-05 1.9e-04 1.0e-03 3.8e-05
2 Liver gene expression Ffar4 0.24 0.07 0.0e+00 0.29 0.3 0.3 0.3 3.2e-32 7.6e-34 2.8e-33 3.9e-33
3 NAcc gene expression Ffar4 0.24 0.05 0.0e+00 0.48 0.46 0.48 0.48 1.4e-83 4.3e-78 5.3e-82 3.3e-83
4 Brain gene expression Ffar4 0.12 0.04 5.6e-17 0.14 0.16 0.15 0.16 1.1e-12 3.4e-15 3.2e-14 3.5e-15
5 BLA gene expression Ffar4 0.31 0.09 1.1e-16 0.28 0.29 0.27 0.28 3.2e-15 6.1e-16 2.2e-14 4.0e-15
6 IC gene expression Ffar4 0.11 0.06 6.1e-04 0.08 0.06 0.04 0.06 3.2e-04 2.0e-03 8.2e-03 1.8e-03
7 PL gene expression Ffar4 0.21 0.08 3.3e-16 0.13 0.16 0.14 0.14 1.9e-14 2.7e-17 2.5e-15 9.8e-15
8 IL gene expression Ffar4 0.19 0.1 2.4e-04 0.12 0.08 0.07 0.1 9.6e-04 4.8e-03 9.9e-03 2.4e-03
9 OFC gene expression Ffar4 0.14 0.08 2.5e-03 0.1 0.05 0.03 0.05 2.8e-03 2.4e-02 8.2e-02 2.7e-02
10 Adipose gene expression Ffar4 0.38 0.08 0.0e+00 0.22 0.22 0.22 0.22 4.8e-24 4.1e-24 9.1e-24 2.0e-24
11 Adipose mRNA stability Ffar4 0.19 0.08 6.5e-11 0.08 0.09 0.1 0.08 1.9e-09 2.7e-10 1.0e-10 7.1e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density3.05.510.2-3.0-3.22.7-2.7-2.82.4-2.51.41.41.7-0.8
Area under the delay curve0.30.51.4-0.40.2-0.40.50.2-0.50.4-1.2-1.21.2-0.7
BMI with tail0.20.81.7-0.5-0.80.7-0.5-1.00.9-1.11.11.11.3-0.3
BMI without tail0.00.10.40.30.2-0.40.30.3-0.40.10.70.7-0.3-0.0
Body weight0.20.93.6-0.8-0.20.3-0.7-0.10.30.21.91.9-0.91.0
Weight adjusted by age0.20.64.2-1.0-0.40.30.1-0.70.30.1-0.4-0.42.1-0.7
Bone surface2.54.98.9-2.7-3.02.4-2.6-2.32.5-2.22.02.00.9-0.3
Bone volume2.55.08.8-3.0-2.82.5-2.6-2.42.3-2.12.12.10.9-0.6
Breakpoint value in progressive ratio session0.10.20.5-0.30.6-0.30.10.5-0.30.4-0.7-0.7-0.5-0.1
Number of licking bursts0.41.33.80.70.5-1.21.10.9-0.80.3-2.0-2.01.3-0.4
Context. condit. distance diff. score1.11.32.6-1.5-0.91.3-1.6-1.31.3-1.40.90.90.00.0
Locomotion velocity, session 11.72.06.21.10.6-1.21.21.3-1.40.3-2.5-2.50.50.8
Locomotion distance, session 10.91.13.00.80.6-1.00.91.1-1.10.4-1.7-1.70.60.7
Locomotion velocity, session 21.11.33.4-1.2-1.30.7-1.0-0.51.1-1.9-1.5-1.50.2-0.9
Locomotion distance, session 20.20.31.2-0.30.0-0.3-0.10.30.3-0.5-1.1-1.1-0.0-0.0
Locomotion velocity, session 30.20.20.6-0.8-0.30.6-0.7-0.40.3-0.60.00.0-0.40.2
Locomotion distance, session 30.40.51.9-0.30.00.5-0.8-0.20.2-0.51.01.0-1.40.1
Stereotopy head waving bouts, day 30.40.41.9-0.6-0.90.4-0.3-0.60.0-0.8-0.2-0.21.4-0.6
Stereotopy head waving duration, day 30.60.72.7-0.7-1.00.4-0.4-0.80.4-0.7-0.8-0.81.7-0.6
Locomotion velocity, session 72.62.84.4-2.0-1.31.8-2.0-1.72.1-1.31.51.50.1-2.1
Locomotion distance, session 71.62.03.5-1.5-1.01.3-1.8-1.31.9-1.01.61.6-0.7-1.3
Stereotopy head waving bouts, day 70.50.61.8-0.1-0.60.4-0.1-0.3-0.5-0.9-1.1-1.11.30.4
Stereotopy head waving duration, day 70.30.41.0-0.2-0.90.6-0.2-0.6-0.2-0.8-0.4-0.41.00.6
Locomotion velocity, session 80.20.30.5-0.6-0.60.4-0.7-0.60.5-0.6-0.5-0.50.0-0.0
Locomotion distance, session 80.71.02.8-1.3-0.81.0-1.3-1.01.4-1.7-0.3-0.30.6-0.3
Degree of sensitization distance0.30.30.9-0.8-0.40.3-0.5-0.50.9-0.2-0.4-0.40.5-0.9
Degree of sensitization stereotypy0.50.61.60.7-0.1-0.10.30.2-0.8-0.3-1.2-1.20.41.2
Conditioned locomotion0.50.52.1-0.20.30.10.2-0.40.20.71.51.5-0.2-0.9
Cocaine response after cond. corrected0.10.10.20.30.3-0.50.40.5-0.00.4-0.4-0.4-0.4-0.2
Cocaine response after cond. not corrected0.10.20.50.10.2-0.30.10.3-0.10.3-0.7-0.7-0.5-0.6
Cocaine response before conditioning0.20.20.9-0.3-0.00.2-0.2-0.2-0.5-0.3-0.9-0.90.1-0.5
Saline control response1.52.14.01.11.9-1.61.51.3-2.01.6-1.7-1.7-0.20.4
Bone: connectivity density4.47.012.5-2.9-3.53.0-2.9-3.02.7-3.12.02.01.8-1.0
Bone: cortical apparent density0.50.72.11.00.2-0.70.70.3-0.70.0-1.4-1.41.2-0.1
Bone: cortical area0.81.33.1-1.2-0.70.9-1.3-0.70.5-0.31.81.8-1.31.0
Bone: cortical porosity1.41.52.8-1.6-1.31.2-1.3-1.21.7-1.6-0.2-0.21.2-0.9
Bone: cortical porosity1.31.42.4-1.6-1.41.2-1.5-1.21.6-1.50.10.10.5-0.9
Bone: cortical thickness1.11.83.31.21.5-1.41.11.4-1.81.6-0.6-0.6-1.31.8
Bone: cortical thickness1.61.94.21.01.1-1.41.21.4-2.01.0-1.7-1.7-0.11.6
Bone: cortical tissue density0.50.82.31.00.1-0.70.70.3-0.6-0.0-1.5-1.51.4-0.2
Condit. Reinf. active minus inactive responses0.10.20.80.30.2-0.10.00.4-0.1-0.0-0.5-0.5-0.90.2
Condit. Reinf. active-inactive response ratio0.20.20.80.50.2-0.10.30.4-0.10.0-0.0-0.0-0.90.7
Condit. Reinf. active responses0.20.21.30.30.6-0.20.10.5-0.20.5-0.3-0.3-1.1-0.0
Condit. Reinf. inactive responses0.10.10.40.10.5-0.30.10.1-0.10.6-0.5-0.5-0.4-0.4
Incentive salience index mean0.81.01.71.01.3-0.90.81.2-0.90.9-0.9-0.9-1.30.7
Condit. Reinf. lever presses2.03.05.61.92.4-1.91.82.0-1.72.0-1.4-1.4-1.00.9
Condit. Reinf. active minus inactive responses2.13.35.2-1.8-1.61.9-1.8-1.91.8-1.62.12.10.9-2.3
Condit. Reinf. active-inactive response ratio1.32.13.6-1.2-1.31.4-1.2-1.61.5-1.41.51.51.3-1.9
Condit. Reinf. active responses0.60.83.1-0.8-0.30.7-0.6-0.70.40.01.81.8-0.1-0.6
Condit. Reinf. inactive responses1.21.73.31.11.4-1.21.01.3-1.71.80.10.1-1.61.5
Condit. Reinf. lever presses0.20.30.90.60.4-0.60.60.5-1.00.6-0.2-0.2-0.2-0.0
Condit. Reinf. lever reinforcers received0.30.41.6-0.5-0.10.4-0.3-0.50.00.21.31.3-0.1-0.6
Conditioned reinforcement - actives0.10.61.0-0.9-1.00.8-0.9-0.30.2-1.0-0.7-0.7-0.41.0
Conditioned reinforcement - inactives0.71.84.3-1.1-1.81.6-1.9-1.11.1-2.1-1.1-1.10.1-0.4
Conditioned locomotion0.20.31.50.2-0.50.2-0.40.1-0.2-0.0-0.5-0.5-0.31.2
Patch foraging indifference point 0 sec0.41.12.20.90.9-1.11.11.4-1.51.1-0.3-0.3-1.01.3
Patch foraging indifference point AUC1.94.67.41.72.1-2.21.82.4-2.72.0-2.6-2.6-0.82.0
Delay disc. indifference point, 0s delay2.32.57.8-2.1-1.31.7-1.2-1.91.0-1.40.20.21.8-2.8
Delay disc. indifference point, 16s delay0.20.31.0-0.00.3-0.50.40.6-0.70.5-1.0-1.00.20.2
Delay disc. indifference point, 2s delay0.50.64.0-0.7-0.70.10.1-0.5-0.0-0.20.20.22.0-0.9
Delay disc. indifference point, 24s delay0.71.12.60.51.1-1.20.81.2-0.91.0-1.6-1.6-0.50.3
Delay disc. indifference point, 4s delay0.50.61.9-0.20.1-0.30.30.1-0.40.1-1.4-1.41.1-0.7
Delay disc. indifference point, 8s delay1.01.73.10.51.1-1.41.61.1-1.31.6-1.8-1.81.0-0.2
Indifference point function ln k1.64.98.1-2.0-2.22.4-2.2-2.32.6-2.22.92.90.4-1.3
Indifference point function log k1.64.98.1-2.0-2.22.4-2.2-2.32.6-2.22.92.90.4-1.3
Patch foraging total patch changes 0 sec0.41.02.30.80.8-1.01.11.3-1.51.2-0.2-0.2-1.01.1
Patch foraging total patch changes 12 sec4.15.68.82.42.0-2.42.52.5-3.02.2-3.0-3.0-0.51.4
Patch foraging total patch changes 18 sec0.51.22.90.90.9-1.11.21.2-1.70.9-1.4-1.40.30.3
Patch foraging total patch changes 24 sec0.31.12.00.41.2-1.00.91.4-1.41.4-0.7-0.7-1.20.5
Patch foraging total patch changes 6 sec3.66.09.52.42.1-2.62.32.9-3.12.3-2.5-2.5-1.52.5
Patch foraging time to switch 0 sec0.20.91.71.20.7-1.11.20.9-0.60.4-1.3-1.30.9-0.3
Patch foraging water rate 0 sec0.41.52.6-1.6-1.11.5-1.5-1.21.0-1.01.31.3-0.5-0.7
Patch foraging water rate 12 sec0.20.61.7-1.0-0.60.8-1.0-0.50.6-0.70.70.7-1.30.4
Patch foraging water rate 18 sec0.71.52.8-1.7-1.01.4-1.6-1.01.5-1.21.31.3-0.8-0.0
Patch foraging water rate 24 sec0.50.81.5-1.2-0.70.9-1.1-0.91.0-0.60.90.9-0.6-0.4
Patch foraging water rate 6 sec0.10.10.2-0.2-0.50.3-0.3-0.30.0-0.30.30.3-0.00.4
Seeking ratio, delayed vs. immediate footshock0.20.30.60.30.8-0.20.30.6-0.60.30.80.8-0.60.5
Distance traveled before self-admin0.51.02.2-1.5-0.81.2-1.1-0.91.0-1.40.80.80.1-0.8
Distance traveled after self-admin1.83.14.9-2.1-2.21.8-1.8-1.81.6-2.11.01.01.9-1.4
Extensor digitorum longus weight0.31.12.9-1.2-0.10.7-1.2-0.91.0-0.51.71.7-0.3-0.8
Bone: elastic displacement0.40.53.60.3-0.60.40.3-0.50.1-0.5-0.1-0.11.9-0.5
Bone: elastic work0.91.14.1-0.8-1.41.2-0.6-1.10.6-1.40.00.02.0-0.7
Bone: endosteal estimation3.89.316.8-4.1-3.63.4-3.8-3.13.6-2.62.92.90.1-0.6
Bone: endosteal perimeter3.58.512.4-3.5-3.53.4-3.5-3.13.3-2.73.03.00.3-0.2
Epididymis fat weight0.52.87.0-1.6-1.21.6-1.1-1.71.2-0.62.62.61.4-1.3
Delta time in closed arm before/after self-admin0.80.71.40.90.8-0.90.51.1-0.61.1-0.2-0.2-1.21.1
Delta time in open arm before/after self-admin1.41.63.0-1.4-1.51.4-1.1-1.51.2-1.7-0.3-0.31.3-1.4
Diff in mean of infusions in LGA sessions0.81.42.7-1.1-1.21.4-1.5-1.31.4-1.10.60.60.1-1.6
Delay discount exponential model param0.40.51.60.2-0.20.5-0.5-0.30.5-0.51.31.3-1.00.5
Extinction: sum of active levers before priming0.20.42.0-0.30.5-0.4-0.40.8-0.20.30.50.5-1.40.5
Active lever presses in extinction session 64.04.17.5-2.7-2.12.1-2.3-2.22.5-2.40.30.32.0-1.7
Bone: final force0.30.51.5-0.7-0.30.1-0.70.10.1-0.00.60.6-1.21.2
Bone: final moment0.30.51.4-0.7-0.40.1-0.60.10.20.10.90.9-1.21.2
Food consumed during 24 hour testing period0.20.41.30.40.2-0.50.20.7-0.40.2-0.5-0.5-1.20.9
Glucose0.10.21.7-0.10.10.2-0.30.1-0.00.10.50.5-1.30.0
Heart weight0.81.32.51.10.5-0.90.71.0-0.51.41.51.5-1.61.1
Delay discount hyperbolic model param0.30.41.30.3-0.10.4-0.5-0.20.5-0.41.01.0-1.10.5
Intermittent access intake day 1-15 change0.42.23.7-1.8-1.91.7-1.7-1.51.3-1.61.61.6-0.60.3
Intermittent access intake escalation0.63.24.9-2.2-2.22.1-2.0-1.91.6-2.11.81.8-0.20.2
Intermittent access intake escalation 22.54.27.5-2.7-2.62.5-2.3-2.31.9-2.71.61.60.0-0.6
Intermitt. access day 1 inactive lever presses0.00.41.6-0.2-0.70.6-0.3-0.70.5-0.6-0.1-0.10.9-1.3
Intermitt. access day 15 inactive lever presses0.20.82.1-0.8-1.41.2-1.2-1.11.1-0.70.30.30.5-0.1
Intermitt. access escalation Index0.10.52.50.1-0.10.70.1-0.90.50.00.70.70.0-1.6
Intermittent access day 1 total infusions0.20.71.6-0.2-1.11.0-1.2-0.80.7-1.2-0.4-0.40.7-0.3
Intermittent access day 15 total infusions0.92.34.2-1.2-1.92.0-2.0-1.71.4-1.81.31.3-0.50.3
Intermittent access terminal intake (last 3 days)1.32.24.3-1.2-2.12.0-2.1-1.71.4-2.10.70.7-0.10.1
Intermittent access total infusions0.81.02.3-0.5-1.41.3-1.5-1.20.9-1.40.30.30.1-0.0
Intermittent access day 1 locomotion0.20.30.70.4-0.70.5-0.8-0.50.7-0.70.40.40.4-0.2
Intermittent access day 15 total locomotion0.10.31.00.6-0.60.0-0.40.10.0-0.3-0.9-0.90.11.0
Intermittent access total locomotion0.50.61.5-0.2-1.10.7-1.2-0.70.8-1.2-0.4-0.40.80.2
Intermittent access standard deviation0.42.24.8-1.5-2.11.8-2.2-1.31.5-1.80.70.7-1.10.1
Left kidney weight0.10.93.50.40.6-0.90.30.9-0.61.00.10.1-1.61.9
Right kidney weight0.42.86.11.21.8-1.81.22.1-1.62.0-0.4-0.4-2.12.5
Cocaine induced anxiety0.92.610.2-1.2-1.31.7-1.1-1.91.4-1.11.31.31.0-3.2
Post-drug Anxiety0.80.93.90.40.10.10.4-0.4-0.11.01.51.50.0-2.0
Baseline Anxiety1.22.14.71.51.4-1.71.41.7-1.32.20.20.2-1.31.7
Tail length0.10.63.0-0.70.3-0.0-0.40.4-0.50.81.01.0-1.7-0.0
Length with tail0.20.84.0-0.60.3-0.3-0.50.5-0.51.10.70.7-2.01.1
Length without tail0.10.81.8-1.2-0.60.7-1.4-0.61.10.10.60.6-0.90.9
Times rat made contact with spout0.81.04.8-1.1-0.80.7-0.6-0.90.5-0.8-0.4-0.41.1-2.2
Lifetime Intake0.60.81.9-0.3-1.31.1-1.4-0.90.7-1.30.20.20.50.4
Liver weight, left0.50.82.30.50.8-0.70.40.8-0.61.20.50.5-1.41.5
Liver weight, right0.40.61.5-1.2-0.80.9-1.0-0.70.6-0.21.11.1-0.2-0.1
Locomotor activity0.20.40.9-0.8-0.60.8-0.4-0.30.3-1.00.30.30.5-0.7
Locomotor testing distance0.10.30.9-0.9-0.70.7-0.3-0.20.0-1.0-0.3-0.30.5-0.2
Locomotor testing rearing0.41.32.8-1.7-1.11.6-1.4-1.11.0-1.70.50.50.7-0.5
Locomotion in novel chamber3.44.57.5-2.6-2.32.2-2.2-2.32.7-2.71.41.41.7-1.3
Locomotion in novel chamber post-restriction0.10.42.90.20.6-0.6-0.00.6-0.40.1-0.6-0.6-0.11.7
Fecal boli incidents, locomotor time 10.51.42.4-1.3-1.11.3-1.4-1.31.1-1.60.50.51.0-1.3
Change in fecal boli incidents, locomotor task1.41.52.31.21.4-1.21.31.3-1.51.3-1.0-1.0-0.91.5
Time >=10cm from walls, locomotor time 10.91.210.60.10.9-0.1-0.50.50.00.4-0.1-0.1-3.30.8
Bouts of movement, locomotor time 10.10.10.4-0.50.00.20.3-0.1-0.30.1-0.6-0.60.60.2
Total resting periods, locomotor time 10.30.31.2-0.40.10.20.20.0-0.30.1-1.1-1.10.60.4
Rest time, locomotor task time 10.40.73.4-0.7-0.61.0-0.2-0.60.3-0.5-0.8-0.81.8-0.2
Distance moved, locomotor task time 10.41.24.81.01.2-1.20.51.3-0.91.00.10.1-2.21.1
Vertical activity count, locomotor time 10.21.25.21.10.9-1.10.71.1-0.81.10.60.6-2.30.8
Time >=10cm from walls, locomotor time 20.10.31.9-0.50.20.6-0.5-0.20.3-0.2-0.6-0.6-1.4-0.4
Bouts of movement, locomotor time 20.41.44.60.20.7-0.91.10.9-1.30.1-2.2-2.20.80.3
Total resting periods, locomotor time 20.41.45.40.00.7-0.81.00.9-1.20.0-2.3-2.30.70.3
Rest time, locomotor task time 20.30.41.8-0.10.4-0.20.40.3-0.40.1-1.3-1.30.7-0.2
Distance moved, locomotor task time 20.30.41.9-0.40.00.4-0.7-0.20.50.00.80.8-1.40.3
Vertical activity count, locomotor time 20.20.41.20.0-0.40.4-0.3-0.10.40.10.90.9-1.1-0.7
Light reinforcement 10.10.52.00.50.1-0.70.50.3-0.40.2-0.9-0.91.40.4
Light reinforcement 20.61.44.41.00.4-1.11.20.5-0.50.5-1.8-1.82.1-0.2
Bone: marrow area3.99.617.0-4.1-3.63.5-3.8-3.23.7-2.72.92.90.2-0.7
Bone: maximum diameter4.79.413.4-3.6-3.53.5-3.7-3.43.2-2.83.33.30.5-0.2
Bone: maximum force0.71.43.0-1.7-1.61.1-1.6-1.01.1-1.20.70.7-0.20.9
Bone: maximum moment0.71.42.8-1.7-1.61.1-1.6-1.01.1-1.01.01.0-0.20.8
Mean time between licks in bursts0.10.91.70.90.9-0.71.00.9-1.11.20.60.6-1.30.9
Mean num. licks in bursts0.82.23.7-1.6-1.21.8-1.6-1.61.4-0.91.91.9-0.5-1.3
Cd content in liver1.01.12.51.30.8-1.01.21.2-1.10.7-0.7-0.7-0.61.6
Co content in liver1.72.03.81.91.3-1.61.71.5-1.91.90.70.7-1.00.8
Cu content in liver3.44.17.52.11.3-2.12.32.1-2.21.9-2.7-2.70.51.1
Fe content in liver1.82.33.41.91.6-1.71.81.7-1.41.4-1.5-1.5-0.41.1
K content in liver0.30.31.40.00.5-0.10.10.30.1-0.2-1.2-1.20.3-0.6
Mg content in liver0.40.51.80.40.6-0.50.40.60.10.1-1.4-1.40.0-0.1
Mn content in liver2.02.28.21.30.8-1.31.20.9-0.70.3-2.9-2.91.30.0
Na content in liver0.91.02.01.21.2-1.00.91.0-0.70.5-1.4-1.40.10.4
Rb content in liver0.10.10.3-0.4-0.30.4-0.5-0.20.50.10.00.0-0.6-0.4
Se content in liver15.218.026.04.94.1-4.94.94.8-4.13.5-5.1-5.1-0.22.1
Sr content in liver0.50.42.20.60.0-0.40.30.5-0.5-0.2-0.8-0.8-0.21.5
Zn content in liver1.51.72.71.41.4-1.51.51.6-1.21.0-1.6-1.60.1-0.5
Bone: minimum diameter5.19.914.9-3.5-3.23.5-3.8-3.23.3-2.63.93.9-1.0-0.8
Time in familiar zone, hab. session 10.60.72.5-0.3-1.10.6-0.4-0.70.3-0.70.80.81.6-0.7
Time in novel zone, hab. session 10.50.51.40.50.8-0.60.30.6-0.30.4-1.2-1.2-0.80.4
Total zone transitions, hab. session 10.20.20.90.0-0.1-0.0-0.10.10.2-0.3-1.0-1.00.50.4
Total locomotion distance, hab. session 11.11.53.71.11.1-1.21.11.2-1.20.8-1.9-1.90.60.2
Locomotion velocity, hab. session 12.02.85.41.61.7-1.81.71.8-1.81.3-2.3-2.30.30.6
Time in familiar zone, hab. session 20.20.20.60.10.2-0.30.60.4-0.80.50.40.40.40.7
Time in novel zone, hab. session 20.10.10.30.4-0.0-0.0-0.2-0.00.3-0.1-0.6-0.6-0.4-0.3
Total zone transitions, hab. session 20.81.01.70.61.0-1.11.01.2-0.90.9-1.3-1.3-0.21.1
Total locomotion distance, hab. session 21.11.52.30.91.2-1.41.31.5-1.41.2-1.4-1.4-0.10.7
Locomotion velocity, hab. session 21.21.62.51.01.3-1.51.31.5-1.41.1-1.6-1.60.20.5
Novel to familiar place preference ratio3.74.88.0-2.5-2.62.4-2.4-2.42.5-2.8-0.5-0.51.7-2.2
Novelty place preference3.95.08.3-2.6-2.72.4-2.5-2.42.5-2.9-0.5-0.51.8-2.2
Time in novel zone, NPP test4.15.08.5-2.6-2.62.5-2.5-2.42.5-2.9-0.5-0.51.7-2.2
Total zone transitions, NPP test0.91.42.31.01.5-1.41.11.5-1.01.3-1.1-1.1-0.90.8
Total locomotion distance, NPP test2.02.84.41.31.8-1.91.72.0-2.01.5-2.1-2.1-0.30.4
Locomotion velocity, NPP test1.92.74.11.31.9-1.91.72.0-1.91.6-1.9-1.9-0.50.3
Intraocular pressure0.20.30.90.3-0.0-0.70.50.4-0.80.3-0.5-0.50.9-0.2
Delta distance traveled before/after self-admin1.41.52.7-1.3-1.61.1-1.2-1.41.2-0.90.80.81.4-1.5
Delta ambulatory time before/after self-admin1.22.03.2-1.4-1.81.4-1.5-1.81.6-1.11.11.11.3-1.2
Parametrial fat weight0.71.63.11.01.7-1.21.11.3-1.51.50.40.4-1.71.0
Pavlov. Cond. lever latency0.10.20.5-0.2-0.70.10.1-0.3-0.2-0.00.60.60.50.2
Pavlov. Cond. magazine entry latency0.91.23.51.11.2-1.10.71.5-0.90.9-0.6-0.6-1.90.8
Pavlov. Cond. change in total contacts0.30.42.50.70.4-0.40.10.60.00.1-0.1-0.1-1.60.4
Pavlov. Cond. index score0.60.81.50.91.1-0.80.41.1-0.50.5-1.0-1.0-1.20.5
Pavlov. Cond. latency score0.50.61.20.71.1-0.70.31.0-0.50.4-0.9-0.9-1.10.2
Pavlov. Cond. lever contacts0.50.61.50.91.2-0.80.51.0-0.40.7-0.9-0.9-0.90.3
Pavlov. Cond. magazine entry number0.30.31.6-0.8-0.40.5-0.3-0.80.2-0.40.10.11.3-0.2
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.10.4-0.10.2-0.0-0.20.4-0.1-0.1-0.40.5
Pavlov. Cond. lever-magazine prob. diff.0.60.71.50.91.1-0.80.51.1-0.50.4-1.0-1.0-1.20.5
Pavlov. Cond. response bias0.40.52.00.90.7-0.60.41.1-0.30.5-0.5-0.5-1.40.5
Pavlov. Cond. lever latency1.21.73.3-1.4-1.11.5-1.3-1.51.5-1.80.80.81.3-0.6
Pavlov. Cond. magazine entry latency0.40.62.90.60.6-0.60.40.8-0.40.8-0.5-0.5-1.7-0.6
Pavlov. Cond. change in total contacts0.40.92.10.81.1-0.90.81.1-1.21.4-0.2-0.2-1.20.1
Pavlov. Cond. index score0.81.23.11.11.0-1.20.91.2-1.21.5-0.7-0.7-1.80.0
Pavlov. Cond. latency score0.61.03.00.80.8-1.00.71.1-1.01.3-0.7-0.7-1.7-0.0
Pavlov. Cond. lever contacts1.42.04.21.61.3-1.71.41.6-1.72.0-0.7-0.7-1.40.7
Pavlov. Cond. magazine entry number1.92.55.5-1.5-1.81.6-1.4-1.81.5-2.01.21.22.3-0.3
Pavlov. Cond. intertrial magazine entries0.81.82.8-1.2-1.31.5-1.4-1.61.3-1.71.31.31.4-0.8
Pavlov. Cond. lever-magazine prob. diff.0.71.02.90.90.9-1.00.81.1-1.11.3-0.8-0.8-1.7-0.1
Pavlov. Cond. response bias1.41.93.71.51.3-1.61.31.7-1.51.9-0.7-0.7-1.70.3
Time in closed arm before self-admin1.01.73.3-1.6-1.31.2-1.1-1.21.2-1.70.10.11.5-1.8
Time in closed arm after self-admin0.10.10.3-0.30.5-0.30.30.4-0.30.20.10.10.5-0.4
Time in open arm before self-admin0.30.30.70.70.4-0.50.60.4-0.20.80.50.50.20.8
Time in open arm after self-admin0.20.30.5-0.5-0.70.3-0.2-0.40.2-0.5-0.7-0.70.60.6
Bone: periosteal estimation2.56.010.7-3.3-2.82.7-3.1-2.42.6-1.92.72.7-0.30.3
Bone: periosteal perimeter2.54.87.2-2.5-2.42.5-2.6-2.32.2-1.82.72.7-0.10.1
Bone: post-yield work0.91.63.4-1.7-1.81.2-1.8-1.21.4-1.40.80.8-0.20.4
Progressive ratio test 1 active lever presses0.20.41.50.1-0.80.6-0.8-0.40.2-0.8-0.3-0.30.61.2
Progressive ratio test 1 breakpoint0.20.42.00.2-0.60.4-0.6-0.2-0.0-0.6-0.4-0.40.51.4
Progressive ratio test 1 inactive lever presses0.51.32.4-1.2-1.61.4-1.5-1.11.0-1.5-0.4-0.41.0-0.5
Progressive ratio test 2 active lever presses1.62.35.0-1.7-2.22.0-2.1-1.61.3-2.0-0.4-0.40.60.3
Progressive ratio test 2 breakpoint1.92.45.2-1.7-2.32.0-2.2-1.71.3-2.0-0.4-0.40.60.4
Progressive ratio test 2 inactive lever presses0.51.73.7-1.0-1.91.6-1.6-1.41.0-1.8-0.8-0.81.2-0.4
Incentive Sensitization - Responses1.23.26.4-2.3-2.52.3-2.4-1.91.8-2.3-0.2-0.20.3-0.5
Incentive Sensitization - Breakpoint1.32.95.9-2.2-2.42.2-2.3-1.81.7-2.2-0.3-0.30.2-0.2
Sum of active levers in priming session hrs 5-60.20.20.30.50.1-0.40.50.5-0.30.50.00.00.2-0.6
Progressive ratio0.20.51.40.21.2-0.70.80.6-0.41.10.70.7-0.3-0.3
Food seeking constrained by brief footshock0.50.63.0-0.50.3-0.2-0.40.8-0.6-0.2-0.6-0.6-1.71.0
Seeking ratio, punishment vs. effort0.30.61.5-0.4-0.4-0.0-0.50.6-0.4-0.5-1.2-1.2-1.01.0
Retroperitoneal fat weight0.10.41.40.60.8-0.50.50.4-0.61.20.70.7-0.10.7
Reaction time number correct0.93.25.5-2.2-1.82.1-1.8-2.32.3-1.71.51.50.9-0.9
Reaction time mean minus median0.10.52.90.3-0.50.4-0.4-0.00.4-0.10.80.8-1.70.8
Reaction time mean minus median AUC0.10.41.70.4-0.30.3-0.00.00.40.11.01.0-1.30.3
Reaction time num false alarms0.20.41.2-0.20.9-0.50.20.5-0.70.90.40.4-1.10.1
Reaction time num false alarms AUC0.20.52.0-0.20.9-0.50.20.7-0.70.90.40.4-1.40.1
Reaction time trials correct on left0.93.25.5-2.2-1.82.1-1.8-2.32.3-1.71.51.50.9-0.9
Reaction time trials on left0.93.15.4-2.1-1.72.1-1.7-2.22.3-1.71.51.50.8-0.8
Reaction time mean0.61.43.91.21.1-1.10.91.6-1.21.1-0.1-0.1-2.01.1
Reaction time mean AUC0.81.84.01.51.4-1.41.21.8-1.41.3-0.3-0.3-2.01.2
Median of all reaction times0.91.42.71.11.3-1.31.01.7-1.31.2-0.3-0.3-1.60.9
Reaction time omissions0.40.73.00.10.00.5-0.4-0.10.9-0.11.31.3-1.7-0.1
Reaction time false alarm rate1.21.63.00.91.6-1.51.01.7-1.71.6-0.4-0.4-1.50.5
Reaction time premature initiation rate0.91.43.10.91.3-1.10.71.3-1.21.4-1.0-1.0-1.81.1
Reaction time premature initiations0.10.32.0-0.30.30.0-0.2-0.00.10.5-0.0-0.0-1.40.7
Std. dev. reaction times0.31.16.00.90.4-0.40.40.9-0.50.90.90.9-2.41.0
Reaction time trials completed0.93.15.4-2.1-1.72.1-1.7-2.22.3-1.71.51.50.8-0.8
Reaction time trials AUC0.82.85.2-2.1-1.62.0-1.6-2.12.3-1.61.41.40.9-1.0
Run reversals in cocaine runway, females0.30.31.0-0.2-0.2-0.50.30.4-0.4-0.0-1.0-1.00.9-0.4
Run reversals in cocaine runway, males2.73.04.82.11.9-2.11.81.9-2.21.7-1.4-1.4-1.30.5
Latency to leave start box in cocaine runway1.52.15.2-1.6-1.11.5-1.3-1.41.1-1.22.32.30.4-0.5
Latency to leave start box in cocaine runway, F2.53.25.5-2.1-1.51.9-1.8-1.81.4-1.92.32.30.7-1.2
Latency to leave start box in cocaine runway, M0.20.20.9-0.3-0.20.2-0.1-0.20.20.10.90.90.20.5
Std. dev. time between licks in bursts1.42.64.32.11.7-2.02.11.8-1.92.1-0.3-0.3-0.41.1
Total sessions with >9 infusions0.30.41.20.60.1-0.40.30.4-0.80.3-0.5-0.50.91.1
Short access day 1 total inactive lever presses1.63.39.8-0.7-2.31.8-1.7-2.11.6-2.20.50.53.1-1.3
Short access day 10 total inactive lever presses0.10.53.9-1.00.10.4-0.1-0.50.10.1-0.1-0.1-0.1-2.0
Short access day 1 total infusions0.40.81.70.90.0-0.30.30.4-0.80.1-1.3-1.31.31.3
Short access day 10 total infusions0.61.02.01.40.5-0.80.60.9-1.20.6-1.1-1.10.21.4
Short access total infusions0.30.41.20.2-0.70.4-0.7-0.30.0-0.7-0.6-0.61.10.9
Short access day 1 locomotion0.30.64.4-0.3-0.60.3-0.2-0.50.1-0.5-0.5-0.52.1-0.3
Short access day 10 total locomotion0.10.30.80.90.1-0.60.20.5-0.0-0.2-0.9-0.90.6-0.1
Short access total locomotion0.20.32.10.5-0.2-0.20.20.1-0.1-0.2-0.8-0.81.50.0
One hour access (0.3 mA shock)3.23.88.1-2.1-2.82.6-2.8-2.22.1-2.50.30.30.1-0.3
Compulsive drug intake0.71.02.0-1.0-0.81.4-1.1-1.41.2-0.70.90.9-0.1-1.0
One hour access (shock baseline)0.10.31.0-0.6-1.00.6-1.0-0.30.3-0.60.10.1-0.50.5
Social response proportion2.22.84.4-1.5-2.01.9-1.7-2.02.1-1.81.11.11.7-1.0
Social responses0.40.61.5-0.4-1.20.7-0.9-0.90.7-0.70.50.50.90.3
Social time0.40.61.11.11.0-1.00.70.9-0.61.0-0.3-0.3-0.60.6
Soleus weight1.13.35.7-2.4-2.01.8-2.1-1.82.1-1.22.22.20.3-0.4
Bone: stiffness0.81.43.5-1.9-1.11.2-1.8-1.11.1-1.10.90.9-0.70.1
Tibialis anterior weight0.72.33.9-2.0-0.81.6-1.8-1.71.5-1.21.51.50.4-2.0
Time to tail flick, vehicle, before self-admin0.60.75.10.1-0.2-0.30.5-0.1-0.2-0.1-0.9-0.92.3-0.5
Time to tail flick, vehicle, after self-admin0.30.52.5-1.60.00.5-0.8-0.30.6-0.30.10.1-0.3-1.4
Time to tail flick, test, before self-admin0.70.81.9-1.3-1.10.8-1.4-0.60.9-1.20.10.10.6-0.3
Time to tail flick, test, after self-admin0.80.83.8-1.0-0.50.5-0.1-0.60.3-0.1-0.3-0.31.7-2.0
Delta time to tail flick, vehicle, before/after SA0.91.02.8-1.7-0.10.9-1.3-0.61.0-0.40.50.5-1.5-1.0
Delta time to tail flick, test, before/after SA0.20.30.8-0.20.1-0.10.6-0.1-0.30.3-0.6-0.60.9-0.9
Tibia length0.20.62.30.20.5-0.70.40.8-0.51.0-0.0-0.0-1.01.5
Ambulatory time before self-admin0.30.91.8-1.3-0.71.1-0.8-0.80.8-1.30.90.90.4-1.2
Ambulatory time after self-admin3.45.58.9-2.7-2.82.6-2.5-2.62.4-3.01.31.32.2-1.7
Bone: tissue strength0.20.20.80.0-0.10.1-0.20.10.50.50.50.5-0.9-0.2
Total heroin consumption0.10.10.40.00.1-0.1-0.20.2-0.00.2-0.3-0.3-0.30.6
Bone: trabecular number2.14.08.5-2.3-2.92.3-2.3-2.31.9-2.31.31.31.3-0.6
Bone: trabecular spacing1.21.83.31.51.8-1.51.41.4-1.61.6-0.6-0.6-1.50.1
Bone: trabecular thickness1.72.44.4-2.1-1.91.9-1.9-1.61.5-1.61.41.40.4-0.0
Bone: trabecular tissue density0.50.81.6-1.2-1.01.1-1.0-1.30.9-0.90.60.60.4-0.4
Water consumed over 24 hours0.91.75.4-1.6-1.21.2-1.3-1.10.8-1.7-0.5-0.51.1-2.3
Number of responses in last shaping day0.30.31.10.8-0.4-0.10.6-0.2-0.20.5-0.3-0.31.01.0