Hub : Genes

Fam227a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr7_113081542_113083859 0.04 0.02 5.9e-07 0.05 0.04 0.04 0.04 8.2e-08 6.2e-07 4.1e-06 2.8e-07
2 NAcc intron excision ratio chr7_113082146_113083859 0.03 0.02 3.9e-06 0.04 0.02 0.02 0.03 2.0e-06 2.2e-04 2.8e-04 3.2e-05
3 pVTA intron excision ratio chr7_113081542_113083859 0.04 0.02 6.6e-03 0.02 0.01 0.02 0.02 1.3e-02 2.3e-02 8.5e-03 1.3e-02
4 Brain intron excision ratio chr7_113081542_113083859 0.04 0.02 3.9e-04 0.05 0.03 0.04 0.04 2.3e-05 3.9e-04 2.2e-04 7.2e-05
5 RMTg intron excision ratio chr7_113081542_113083859 0.22 0.1 8.9e-04 0.06 0.12 0.05 0.06 1.2e-02 3.8e-04 2.2e-02 1.3e-02
6 PL intron excision ratio chr7_113081542_113082077 0.04 0.02 8.1e-05 0.01 0.02 0.02 0.02 1.6e-02 1.1e-03 1.2e-03 1.2e-03
7 PL intron excision ratio chr7_113081542_113083859 0.07 0.03 5.4e-08 0.02 0.06 0.05 0.05 1.1e-03 7.0e-07 1.5e-06 1.6e-06
8 BLA gene expression Fam227a 0.11 0.06 8.4e-05 0.06 0.06 0.04 0.03 4.5e-04 3.0e-04 3.4e-03 8.9e-03
9 BLA intron excision ratio chr7_113081542_113083859 0.1 0.06 4.7e-04 0.01 0.04 0.05 0.03 1.0e-01 4.1e-03 1.4e-03 1.8e-02
10 pVTA intron excision ratio chr7_113078062_113078597 0.05 0.03 8.2e-04 0.02 0.04 0.04 0.04 5.6e-03 2.2e-04 2.0e-04 5.2e-04
11 OFC gene expression Fam227a 0.29 0.13 1.0e-03 0.14 0.06 0.1 0.14 3.9e-04 1.4e-02 2.4e-03 4.5e-04
12 IC gene expression Fam227a 0.1 0.05 2.6e-03 0.07 0.04 0.05 0.06 6.0e-04 1.4e-02 5.3e-03 2.3e-03
13 Brain gene expression Fam227a 0.15 0.06 8.3e-13 0.13 0.15 0.14 0.15 5.9e-12 4.1e-14 1.9e-13 1.3e-13
14 NAcc gene expression Fam227a 0.09 0.04 5.3e-13 0.09 0.08 0.09 0.09 7.3e-13 2.1e-12 1.7e-13 4.5e-13
15 PL gene expression Fam227a 0.1 0.05 6.7e-09 0.1 0.09 0.09 0.09 1.1e-10 2.2e-10 2.5e-10 2.4e-10
16 pVTA gene expression Fam227a 0.07 0.05 5.5e-04 0.04 0.03 0.03 0.03 2.5e-04 1.2e-03 2.0e-03 1.3e-03
17 IL gene expression Fam227a 0.32 0.11 3.5e-05 0.08 0.13 0.06 0.1 4.9e-03 5.3e-04 1.5e-02 1.8e-03
18 PL intron excision ratio chr7_113082146_113083859 0.05 0.03 1.5e-04 0.01 0.02 0.02 0.02 2.3e-02 5.4e-03 6.3e-03 1.9e-03
19 Eye intron excision ratio chr7_113059999_113060383 0.52 0.19 6.6e-03 0.03 -0 0 0.01 1.3e-01 3.8e-01 2.9e-01 2.3e-01
20 OFC intron excision ratio chr7_113081542_113083859 0.45 0.17 1.7e-03 -0.01 -0 0.02 -0.01 8.7e-01 3.9e-01 9.5e-02 5.8e-01
21 Adipose gene expression Fam227a 0.07 0.04 9.9e-07 0.05 0.06 0.05 0.05 2.5e-06 2.6e-07 1.6e-06 3.4e-06
22 BLA intron excision ratio chr7_113081542_113082077 0.08 0.05 2.1e-03 0.02 0.03 0.05 0.03 2.5e-02 1.5e-02 8.3e-04 1.8e-02
23 Brain intron excision ratio chr7_113081542_113082077 0.05 0.03 1.1e-03 0.03 0.03 0.03 0.02 5.9e-04 1.3e-03 3.7e-04 5.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bone: apparent density0.10.11.50.1-0.10.20.20.10.00.20.4-0.1-0.10.10.10.10.20.40.0-0.2-0.30.1-1.20.10.5-0.6
Area under the delay curve2.22.66.82.6-2.42.52.52.2-2.52.1-0.72.6-0.2-0.6-0.6-1.1-0.3-0.7-0.6-1.2-1.71.01.5-0.1-1.30.3
BMI with tail0.41.23.2-1.61.7-1.7-1.7-1.51.6-1.10.4-1.8-0.41.00.81.20.50.70.71.10.7-1.1-0.60.60.20.0
BMI without tail0.51.64.6-1.61.4-1.5-1.4-1.62.0-1.71.3-1.9-0.41.00.91.00.70.80.90.61.3-1.0-2.10.20.5-0.1
Body weight1.04.513.0-3.43.4-3.5-3.3-2.83.6-3.00.3-3.41.30.30.00.6-0.50.00.11.12.3-0.5-1.9-0.81.30.7
Weight adjusted by age0.40.63.9-1.10.9-0.9-0.8-0.80.5-1.00.5-0.0-0.40.50.80.20.60.50.50.50.6-0.4-1.5-0.0-0.22.0
Bone surface0.20.31.90.3-0.40.30.40.5-0.70.7-0.50.80.4-0.5-0.3-0.6-0.20.0-0.4-0.3-0.80.6-1.4-0.1-0.50.8
Bone volume0.00.00.40.1-0.20.10.20.0-0.20.20.10.4-0.10.00.10.10.20.30.00.1-0.10.2-0.60.20.00.3
Breakpoint value in progressive ratio session0.10.10.80.3-0.40.10.10.3-0.20.6-0.50.30.1-0.6-0.5-0.2-0.2-0.2-0.3-0.2-0.50.3-0.10.0-0.9-0.4
Number of licking bursts0.30.52.21.0-1.01.01.00.5-0.90.20.51.0-0.90.40.6-0.10.60.20.8-0.2-0.5-0.30.70.2-1.50.0
Context. condit. distance diff. score3.84.711.6-3.23.2-3.4-3.4-3.12.9-2.80.9-2.4-0.01.31.01.80.71.01.22.23.1-1.2-0.60.71.81.2
Locomotion velocity, session 11.21.35.40.3-0.30.50.81.0-0.80.6-1.60.81.6-1.1-1.1-1.9-1.1-1.1-1.1-1.3-0.82.3-0.5-1.7-1.20.0
Locomotion distance, session 12.73.411.12.7-2.42.32.52.3-3.12.3-0.83.3-0.1-0.2-0.4-1.30.0-0.3-0.3-1.2-2.81.70.4-0.2-2.60.3
Locomotion velocity, session 20.60.73.30.4-0.30.20.30.9-1.31.6-1.50.80.5-0.3-0.4-0.6-0.4-0.4-0.4-0.2-1.80.8-0.30.0-0.2-1.0
Locomotion distance, session 23.95.411.93.2-3.23.23.23.2-3.23.1-1.53.00.7-1.4-1.5-2.2-1.1-1.5-1.5-2.2-3.52.20.5-0.8-1.7-1.2
Locomotion velocity, session 31.71.93.9-1.91.9-1.8-1.6-2.01.1-1.71.1-0.6-0.81.61.61.51.21.21.41.91.4-0.8-0.51.0-0.01.1
Locomotion distance, session 31.81.94.50.00.0-0.2-0.0-1.0-0.4-0.91.91.2-2.12.12.11.62.01.71.91.60.8-0.91.11.7-1.31.2
Stereotopy head waving bouts, day 30.70.92.9-0.50.3-0.3-0.20.30.50.1-1.4-0.81.7-1.1-1.3-1.2-1.4-1.1-1.2-0.90.10.9-0.8-1.40.00.2
Stereotopy head waving duration, day 31.41.75.2-1.51.3-1.3-1.1-0.21.3-0.3-1.9-1.82.3-1.3-1.5-1.2-1.5-1.1-1.3-0.70.50.8-1.3-1.80.60.3
Locomotion velocity, session 70.30.31.4-0.60.4-0.8-0.6-0.50.7-1.0-0.1-0.50.20.10.10.30.10.10.20.31.2-0.11.0-0.3-0.2-0.5
Locomotion distance, session 70.60.72.30.5-0.40.10.30.50.4-0.8-0.4-0.10.9-0.9-0.8-1.0-0.9-0.8-0.9-1.11.21.21.2-1.50.5-1.0
Stereotopy head waving bouts, day 71.92.26.1-2.52.4-2.5-2.5-1.81.2-1.1-0.1-1.3-0.21.31.11.20.91.11.21.80.8-0.9-1.50.70.21.8
Stereotopy head waving duration, day 71.92.35.8-2.32.3-2.2-2.4-1.71.1-0.70.1-1.5-0.61.51.31.61.11.31.41.90.5-1.6-1.41.20.71.4
Locomotion velocity, session 81.01.23.1-1.21.5-1.6-1.6-0.30.6-0.2-1.5-1.01.8-0.7-0.9-0.9-1.0-1.0-0.7-0.10.71.4-1.4-1.01.30.3
Locomotion distance, session 80.30.41.4-0.90.9-1.0-1.0-0.70.5-0.40.3-0.5-0.10.60.50.60.20.20.30.80.2-0.1-1.10.51.20.3
Degree of sensitization distance3.03.17.2-0.50.5-0.5-0.50.71.6-0.5-1.8-2.12.7-2.4-2.3-1.8-2.4-2.1-2.4-2.00.91.4-0.5-2.72.2-1.8
Degree of sensitization stereotypy1.61.74.9-2.12.1-2.1-2.2-1.50.6-0.5-0.1-0.8-0.51.31.21.21.11.21.31.80.1-0.8-1.51.00.21.4
Conditioned locomotion0.30.31.1-0.60.6-0.9-0.6-0.20.7-0.7-0.3-0.90.5-0.1-0.1-0.3-0.5-0.5-0.3-0.20.40.3-0.5-0.71.1-0.0
Cocaine response after cond. corrected0.80.92.20.3-0.20.30.20.9-0.51.0-1.50.21.1-1.1-0.8-1.3-1.4-1.4-1.5-0.9-1.51.3-0.4-0.9-0.1-0.9
Cocaine response after cond. not corrected0.40.52.30.2-0.20.20.10.7-0.51.0-1.10.10.7-0.8-0.5-0.8-1.0-1.0-1.1-0.5-1.50.7-0.6-0.40.1-0.5
Cocaine response before conditioning0.70.92.9-0.0-0.10.0-0.1-0.60.0-0.11.20.2-1.41.11.11.41.21.11.21.10.2-1.70.01.5-0.20.9
Saline control response0.70.92.2-1.31.2-0.8-0.7-1.41.1-1.01.0-0.6-0.60.61.11.10.60.70.81.30.8-0.9-1.50.90.8-0.4
Bone: connectivity density0.10.22.5-0.30.3-0.3-0.2-0.10.4-0.3-0.1-0.40.6-0.4-0.4-0.3-0.10.1-0.3-0.3-0.00.6-1.6-0.50.3-0.4
Bone: cortical apparent density1.62.25.3-0.80.8-0.5-0.3-1.70.8-1.82.3-0.0-2.02.12.21.82.02.02.01.61.3-1.40.61.4-0.0-0.5
Bone: cortical area0.50.82.50.0-0.20.40.50.7-0.10.7-1.6-0.31.4-1.5-1.3-1.0-1.2-1.2-1.1-0.7-0.50.90.6-0.9-0.4-0.7
Bone: cortical porosity0.70.72.3-0.30.4-0.2-0.30.40.20.9-1.3-0.80.9-1.4-1.0-0.4-1.3-1.5-1.2-0.2-0.70.7-0.5-0.20.9-1.3
Bone: cortical porosity1.51.64.8-0.50.6-0.5-0.50.60.31.1-2.2-0.91.8-2.0-1.7-1.1-2.0-2.0-1.8-0.6-0.71.2-0.4-0.90.9-1.2
Bone: cortical thickness0.50.84.51.0-1.01.41.50.7-0.70.9-0.50.60.2-0.8-0.5-0.3-0.5-0.6-0.5-0.3-0.40.32.10.1-0.8-1.2
Bone: cortical thickness1.61.96.31.7-1.71.92.01.5-1.51.5-1.01.40.6-1.1-1.2-1.1-0.7-1.0-0.6-1.0-1.11.62.5-0.5-1.6-1.0
Bone: cortical tissue density1.52.04.8-0.80.8-0.5-0.3-1.70.8-1.82.2-0.0-1.82.02.11.71.81.91.91.51.4-1.30.61.2-0.0-0.5
Condit. Reinf. active minus inactive responses0.10.21.1-0.0-0.20.30.4-0.30.4-0.80.60.1-0.20.00.10.10.20.20.2-0.10.50.10.7-0.2-1.0-0.4
Condit. Reinf. active-inactive response ratio0.40.51.5-0.70.5-0.4-0.3-1.00.8-1.20.8-0.3-0.60.60.70.70.50.70.60.71.2-0.40.70.3-0.50.0
Condit. Reinf. active responses0.40.63.2-0.0-0.30.30.3-0.70.8-1.21.8-0.3-1.00.70.70.80.80.80.90.20.7-0.80.60.4-0.5-0.3
Condit. Reinf. inactive responses0.70.95.00.1-0.20.20.1-0.80.8-1.22.2-0.5-1.31.11.01.21.10.91.20.30.7-1.40.30.70.2-0.1
Incentive salience index mean0.20.21.00.2-0.40.40.5-0.30.6-1.01.0-0.1-0.40.10.20.10.20.20.2-0.30.70.10.8-0.3-0.6-0.2
Condit. Reinf. lever presses0.20.31.50.2-0.40.20.2-0.30.8-1.11.2-0.6-0.60.30.10.30.30.30.3-0.31.0-0.21.1-0.2-0.00.0
Condit. Reinf. active minus inactive responses1.21.64.01.3-1.11.11.31.4-1.21.1-1.41.21.3-1.5-1.5-1.7-1.2-1.1-1.3-1.4-0.12.01.0-1.3-0.60.3
Condit. Reinf. active-inactive response ratio1.11.33.60.6-0.50.50.71.0-0.50.7-1.50.41.5-1.5-1.5-1.6-1.4-1.4-1.5-1.2-0.21.90.7-1.4-0.00.2
Condit. Reinf. active responses1.11.53.41.0-0.90.71.01.3-1.21.2-1.81.21.5-1.5-1.5-1.6-1.3-1.1-1.3-1.0-0.21.61.1-1.1-1.00.9
Condit. Reinf. inactive responses0.50.62.40.7-0.90.50.50.8-1.00.8-1.11.20.5-0.6-0.6-0.6-0.4-0.3-0.4-0.2-0.20.51.4-0.2-1.61.3
Condit. Reinf. lever presses0.20.31.21.0-1.10.60.50.7-0.50.40.10.4-0.2-0.4-0.1-0.4-0.3-0.1-0.5-0.70.3-0.70.4-0.30.60.7
Condit. Reinf. lever reinforcers received1.11.53.21.0-1.00.70.91.4-1.01.2-1.80.91.5-1.6-1.6-1.7-1.4-1.3-1.5-1.2-0.21.40.8-1.3-0.40.7
Conditioned reinforcement - actives1.42.35.12.1-2.01.61.81.7-2.01.6-1.32.30.6-1.0-1.0-1.4-1.0-1.3-1.2-0.9-1.21.62.2-0.5-2.0-1.0
Conditioned reinforcement - inactives2.13.06.52.6-2.52.12.22.1-1.71.6-1.01.60.9-1.5-1.8-1.8-1.3-1.5-1.5-2.0-1.01.52.1-1.2-0.7-2.3
Conditioned locomotion2.43.15.21.4-1.71.51.61.8-1.42.1-2.21.01.8-1.8-2.2-1.9-2.1-2.3-2.1-1.5-1.81.80.9-1.1-1.5-1.9
Patch foraging indifference point 0 sec0.30.62.9-0.40.00.20.2-0.11.1-0.70.4-1.50.4-0.7-0.4-0.4-0.7-0.6-0.5-0.80.2-0.0-0.9-0.81.3-1.7
Patch foraging indifference point AUC1.11.64.11.9-1.71.82.01.5-1.60.6-0.31.90.1-0.4-0.3-1.4-0.5-0.8-0.6-1.3-0.41.21.9-1.0-1.30.5
Delay disc. indifference point, 0s delay0.30.31.10.2-0.00.50.30.40.10.7-0.7-0.50.3-1.1-1.0-0.3-0.9-0.8-0.9-0.4-0.20.20.6-0.20.2-0.9
Delay disc. indifference point, 16s delay2.52.77.22.7-2.42.52.52.3-2.62.2-0.72.7-0.3-0.6-0.4-1.1-0.3-0.8-0.6-1.2-1.91.01.2-0.1-1.10.4
Delay disc. indifference point, 2s delay4.14.612.73.0-2.82.92.82.5-3.53.6-1.33.3-0.4-0.6-0.6-0.7-0.0-0.4-0.5-0.6-3.30.72.00.9-2.8-1.1
Delay disc. indifference point, 24s delay0.80.92.61.1-0.80.80.91.2-1.10.2-0.81.30.4-0.6-0.6-1.5-0.5-0.6-0.6-1.2-0.51.60.5-1.3-0.71.0
Delay disc. indifference point, 4s delay1.51.63.81.7-1.61.91.91.7-2.02.0-0.91.90.0-0.8-0.7-0.9-0.4-0.6-0.7-1.0-1.50.80.8-0.2-0.9-0.2
Delay disc. indifference point, 8s delay1.11.34.72.2-2.02.02.01.5-1.40.90.11.8-0.2-0.3-0.3-0.8-0.2-0.6-0.4-1.2-0.70.61.3-0.4-0.40.3
Indifference point function ln k1.22.15.4-2.32.2-2.2-2.3-1.91.8-1.20.5-1.9-0.00.60.51.40.71.00.91.70.9-1.1-1.51.01.20.1
Indifference point function log k1.22.15.4-2.32.2-2.2-2.3-1.91.8-1.20.5-1.9-0.00.60.51.40.71.00.91.70.9-1.1-1.51.01.20.1
Patch foraging total patch changes 0 sec0.20.43.4-0.1-0.20.70.6-0.00.8-0.40.7-1.20.1-0.4-0.1-0.2-0.5-0.4-0.2-0.7-0.0-0.4-0.7-0.51.1-1.8
Patch foraging total patch changes 12 sec0.70.91.90.7-0.91.01.11.0-0.40.6-0.90.10.8-1.4-1.0-1.2-1.4-1.4-1.3-1.1-0.70.80.6-1.0-0.4-0.6
Patch foraging total patch changes 18 sec1.21.94.31.2-1.21.41.41.5-0.40.7-1.1-0.11.3-1.7-1.7-1.9-1.7-1.8-1.5-2.1-0.61.30.5-1.8-0.1-1.5
Patch foraging total patch changes 24 sec0.30.52.61.1-1.01.11.30.5-0.0-0.30.40.3-0.1-0.4-0.4-0.4-0.1-0.1-0.1-0.90.60.41.6-0.6-0.4-1.4
Patch foraging total patch changes 6 sec1.01.63.91.2-1.51.82.01.4-0.60.6-0.50.30.9-1.2-1.1-1.6-1.3-1.3-1.2-1.8-0.51.40.0-1.5-0.1-1.9
Patch foraging time to switch 0 sec0.20.52.60.5-0.50.1-0.11.0-0.71.6-1.3-0.20.4-0.6-0.7-0.4-0.8-0.7-1.0-0.4-1.10.3-0.40.10.70.1
Patch foraging water rate 0 sec0.40.83.9-0.80.8-0.3-0.0-0.81.7-2.01.0-1.20.5-0.3-0.3-0.3-0.1-0.10.2-0.61.40.3-0.9-1.20.6-1.0
Patch foraging water rate 12 sec0.30.71.8-0.80.7-0.1-0.1-1.00.9-0.91.3-0.8-0.80.60.71.00.90.91.10.70.3-1.1-0.90.70.6-1.1
Patch foraging water rate 18 sec0.30.52.8-0.70.7-0.1-0.1-0.61.1-1.40.9-0.90.2-0.20.2-0.2-0.00.00.0-0.40.8-0.1-1.7-0.80.8-0.5
Patch foraging water rate 24 sec1.31.94.9-2.22.0-1.7-1.6-1.62.2-1.90.7-2.10.40.00.40.50.10.30.40.61.5-1.0-2.2-0.31.8-0.4
Patch foraging water rate 6 sec1.11.54.7-1.01.0-0.9-0.9-1.61.6-2.12.2-0.9-1.21.11.31.31.21.11.21.01.4-1.3-1.20.70.20.5
Seeking ratio, delayed vs. immediate footshock0.30.41.20.5-0.40.40.70.2-0.60.30.60.5-0.91.10.80.50.80.60.80.1-0.4-0.9-0.50.6-0.10.5
Distance traveled before self-admin1.41.94.72.1-1.91.91.82.2-1.82.2-1.00.90.1-0.8-0.8-1.0-1.0-1.2-1.1-1.4-1.80.30.6-0.30.3-1.4
Distance traveled after self-admin1.51.95.20.6-0.60.50.41.30.10.4-1.1-0.51.6-1.8-1.8-2.0-2.0-2.3-1.9-2.1-0.51.5-1.0-2.00.9-0.1
Extensor digitorum longus weight0.31.32.91.2-1.11.71.50.6-1.41.61.01.1-1.61.01.00.91.11.01.20.3-1.7-0.9-0.51.6-0.2-0.6
Bone: elastic displacement0.20.21.2-0.80.7-0.6-0.4-0.20.5-0.5-0.2-0.80.5-0.2-0.1-0.3-0.2-0.1-0.2-0.10.3-0.2-1.1-0.50.10.1
Bone: elastic work1.31.74.7-0.70.5-0.3-0.10.70.40.5-2.1-1.22.2-1.7-1.8-1.6-2.0-1.7-1.8-1.1-0.81.5-0.8-1.70.4-1.0
Bone: endosteal estimation0.71.64.8-0.60.3-0.8-0.70.70.30.5-2.1-0.72.2-1.7-1.6-1.6-1.7-1.5-1.6-1.1-0.51.5-1.7-1.70.5-0.2
Bone: endosteal perimeter0.51.14.0-1.10.9-1.2-1.10.20.50.3-2.0-0.91.8-1.3-1.2-1.0-1.2-1.1-1.0-0.3-0.41.2-1.3-1.1-0.10.7
Epididymis fat weight1.03.611.7-3.22.9-3.4-3.2-2.73.1-2.3-0.4-2.81.3-0.1-0.11.0-0.40.1-0.01.72.2-0.10.1-0.10.6-0.1
Delta time in closed arm before/after self-admin0.80.85.20.9-1.11.21.30.6-0.80.7-0.60.90.5-0.5-0.5-0.5-0.7-0.7-0.7-0.3-0.50.82.3-0.1-1.1-0.7
Delta time in open arm before/after self-admin0.10.11.80.2-0.0-0.0-0.10.3-0.30.30.00.1-0.1-0.00.1-0.2-0.1-0.3-0.2-0.3-0.4-0.1-1.3-0.10.20.6
Diff in mean of infusions in LGA sessions0.30.31.5-0.2-0.2-0.4-0.20.10.3-0.4-0.60.30.8-0.7-0.7-0.8-0.5-0.3-0.6-0.60.31.0-0.3-1.1-1.2-0.2
Delay discount exponential model param2.32.56.7-2.62.3-2.4-2.4-2.12.5-2.10.6-2.60.20.60.51.00.20.60.61.21.8-0.9-1.40.11.3-0.4
Extinction: sum of active levers before priming1.61.87.71.2-1.40.81.11.4-1.71.9-1.81.70.5-1.1-1.1-1.0-0.8-0.9-1.1-0.5-1.91.31.0-0.2-2.80.6
Active lever presses in extinction session 60.20.21.80.1-0.6-0.00.20.3-0.40.6-0.80.4-0.1-0.6-0.4-0.3-0.2-0.2-0.4-0.1-0.70.40.0-0.1-1.3-0.6
Bone: final force1.11.84.90.3-0.50.50.51.3-0.51.2-2.2-0.12.1-1.9-1.8-1.7-1.9-1.6-1.9-1.3-1.21.40.1-1.5-0.1-0.4
Bone: final moment1.22.05.30.3-0.40.40.61.3-0.41.1-2.3-0.22.2-2.0-1.9-1.9-2.0-1.8-2.1-1.4-1.01.6-0.1-1.7-0.0-0.5
Food consumed during 24 hour testing period0.60.82.7-0.10.10.10.10.5-0.10.8-1.60.01.2-1.4-1.4-1.0-1.3-1.5-1.2-0.5-0.41.20.3-0.7-0.4-0.5
Glucose0.30.42.4-0.30.4-0.7-0.8-0.41.4-0.70.1-1.60.5-0.7-0.7-0.0-0.8-0.9-0.5-0.30.60.20.3-0.50.4-0.3
Heart weight1.32.05.2-1.81.7-1.7-1.8-0.51.7-0.8-1.6-2.12.3-1.2-1.3-1.1-1.4-1.0-1.1-0.60.50.8-1.9-1.80.80.9
Delay discount hyperbolic model param2.42.77.5-2.72.4-2.6-2.5-2.12.6-2.30.6-2.70.40.50.40.80.10.50.51.02.0-0.8-1.5-0.21.4-0.1
Intermittent access intake day 1-15 change0.10.20.6-0.30.3-0.3-0.4-0.60.2-0.20.7-0.3-0.70.80.40.60.50.60.40.6-0.0-0.7-0.40.7-0.10.1
Intermittent access intake escalation0.20.41.0-0.20.3-0.3-0.4-0.60.1-0.31.0-0.1-1.01.00.70.70.80.80.70.60.1-0.8-0.50.8-0.00.3
Intermittent access intake escalation 20.30.41.1-0.40.2-0.3-0.3-0.70.5-0.61.1-0.4-0.80.90.50.70.70.70.70.50.5-0.7-0.40.5-0.1-0.7
Intermitt. access day 1 inactive lever presses0.52.06.60.30.1-0.3-0.30.90.9-0.3-1.0-1.41.9-2.0-1.9-1.5-1.8-1.8-1.7-1.80.81.4-0.1-2.02.6-0.9
Intermitt. access day 15 inactive lever presses0.40.92.41.0-0.90.50.71.1-0.20.2-0.50.00.9-1.0-1.2-1.4-1.0-1.0-1.1-1.60.11.2-0.4-1.40.9-1.3
Intermitt. access escalation Index0.50.72.60.2-0.20.20.3-0.4-0.50.30.90.6-1.61.01.21.11.21.11.10.9-0.0-1.00.11.4-0.2-0.8
Intermittent access day 1 total infusions2.74.47.72.5-2.42.02.02.7-2.42.8-2.61.81.6-2.2-2.2-2.3-1.9-2.1-2.0-1.9-2.12.12.0-1.2-1.1-0.7
Intermittent access day 15 total infusions1.11.64.01.9-1.81.61.61.7-2.01.9-0.91.60.2-0.7-0.9-1.1-0.6-0.8-0.8-1.0-1.70.91.1-0.2-1.0-0.1
Intermittent access terminal intake (last 3 days)1.41.94.42.0-1.91.61.71.9-2.12.0-1.21.70.4-0.7-0.9-1.3-0.8-1.0-0.9-1.1-1.71.01.3-0.4-1.1-0.2
Intermittent access total infusions4.45.28.92.9-2.82.42.53.0-2.83.0-2.52.21.5-1.9-2.2-2.4-2.0-2.2-2.1-2.1-2.42.12.3-1.2-1.7-0.6
Intermittent access day 1 locomotion1.92.44.22.0-2.01.71.72.0-1.41.9-1.50.91.1-1.6-1.6-1.7-1.5-1.6-1.5-1.8-1.31.11.4-1.1-0.5-1.4
Intermittent access day 15 total locomotion0.71.22.31.2-1.10.70.71.2-0.71.1-1.40.41.3-1.2-1.5-1.3-1.3-1.4-1.4-1.2-0.61.01.4-1.0-0.5-0.2
Intermittent access total locomotion1.72.04.21.2-1.10.70.71.3-0.40.8-1.60.11.8-1.6-2.0-1.8-2.0-2.1-2.0-1.7-0.11.51.4-1.7-0.2-1.6
Intermittent access standard deviation1.63.39.41.1-1.21.01.01.8-0.21.3-2.0-0.62.3-2.3-2.5-2.2-2.9-3.1-3.1-2.1-1.11.70.8-1.91.0-0.5
Left kidney weight1.99.124.3-4.14.5-4.5-4.3-1.73.3-1.7-4.0-3.54.9-2.7-2.6-1.6-3.2-2.6-2.60.41.62.6-1.6-2.70.91.5
Right kidney weight2.812.930.3-5.15.3-5.4-5.2-2.44.6-2.6-3.9-4.75.5-3.1-3.0-1.6-3.8-3.1-3.10.32.32.5-1.8-3.21.71.2
Cocaine induced anxiety0.20.31.1-0.80.9-1.0-1.0-0.70.6-0.4-0.6-0.40.6-0.1-0.30.1-0.10.00.00.50.50.20.6-0.1-0.70.2
Post-drug Anxiety1.01.12.8-1.51.5-1.4-1.4-1.61.3-1.70.8-0.8-0.30.70.70.80.81.01.00.91.5-0.5-0.40.1-0.10.2
Baseline Anxiety0.30.31.00.3-0.60.70.90.1-0.4-0.21.00.7-0.90.60.80.20.80.60.80.0-0.0-0.3-0.30.3-0.3-0.4
Tail length0.62.47.1-1.81.8-1.7-1.6-1.92.4-2.71.8-2.0-0.10.60.70.70.50.70.90.52.4-1.0-2.5-0.31.61.0
Length with tail1.04.211.1-3.23.1-3.1-2.9-2.73.3-3.20.6-2.81.30.10.20.4-0.30.10.10.92.6-0.2-2.4-0.91.51.5
Length without tail1.03.37.6-2.62.7-2.5-2.3-1.32.4-1.5-1.7-2.62.8-1.5-1.5-1.0-1.9-1.5-1.5-0.01.31.0-1.2-1.81.10.4
Times rat made contact with spout0.30.42.30.2-0.10.30.6-0.50.5-1.10.70.5-0.00.2-0.4-0.10.20.20.2-0.11.30.41.1-0.4-1.50.6
Lifetime Intake5.56.710.53.1-3.02.62.73.2-2.93.2-3.02.21.9-2.5-2.7-2.7-2.4-2.6-2.5-2.4-2.52.62.9-1.5-2.0-1.0
Liver weight, left0.61.02.7-1.31.0-1.4-1.2-1.50.8-1.10.5-0.0-0.61.01.01.20.81.00.91.71.6-0.30.61.0-0.50.1
Liver weight, right4.06.915.1-3.73.7-3.9-3.8-3.83.1-3.21.7-2.3-1.02.12.12.81.72.12.03.23.3-2.0-0.91.71.11.1
Locomotor activity0.50.83.1-1.81.6-1.4-1.4-1.31.3-0.7-0.5-1.00.9-0.20.10.1-0.6-0.4-0.30.80.50.2-1.4-0.1-0.3-0.1
Locomotor testing distance0.10.30.8-0.30.2-0.1-0.2-0.70.4-0.40.7-0.1-0.60.60.90.60.30.20.40.70.1-0.5-0.40.6-0.1-0.8
Locomotor testing rearing0.10.31.0-1.00.6-0.6-0.7-0.60.60.1-0.8-0.30.7-0.4-0.50.1-0.6-0.4-0.30.6-0.40.4-0.10.1-0.3-0.7
Locomotion in novel chamber2.02.67.1-0.2-0.0-0.1-0.1-1.1-0.0-0.72.50.6-2.72.22.42.12.52.42.41.60.5-2.1-0.52.1-0.20.8
Locomotion in novel chamber post-restriction0.81.34.51.0-1.21.01.00.2-1.20.90.81.5-1.60.81.01.01.31.11.10.7-0.7-1.01.11.6-2.10.8
Fecal boli incidents, locomotor time 11.31.94.61.0-1.21.21.21.6-0.40.5-1.20.11.6-1.6-1.7-2.1-1.7-1.9-1.8-2.1-0.21.60.4-2.10.1-0.2
Change in fecal boli incidents, locomotor task1.11.12.8-1.61.4-1.7-1.3-1.70.8-1.50.5-0.0-0.01.01.10.70.70.90.91.51.20.2-0.70.4-0.60.6
Time >=10cm from walls, locomotor time 10.90.92.1-0.70.5-0.6-0.50.20.50.1-1.4-0.81.3-1.3-1.3-1.2-1.5-1.3-1.3-0.7-0.11.3-0.2-1.30.6-1.0
Bouts of movement, locomotor time 10.20.30.9-0.60.6-0.9-0.9-0.60.5-0.7-0.4-0.10.0-0.3-0.30.0-0.1-0.1-0.10.40.70.60.8-0.2-0.9-0.2
Total resting periods, locomotor time 10.20.30.6-0.20.1-0.4-0.30.00.3-0.3-0.8-0.10.4-0.7-0.7-0.6-0.6-0.6-0.5-0.30.30.80.7-0.7-0.6-0.5
Rest time, locomotor task time 10.70.92.4-0.0-0.1-0.3-0.30.40.7-0.4-1.0-0.81.5-1.4-1.4-1.1-1.2-1.1-1.2-1.10.91.10.6-1.60.3-0.4
Distance moved, locomotor task time 10.60.81.8-1.21.0-0.8-0.7-1.20.5-0.50.8-0.4-0.71.21.11.31.01.11.11.3-0.0-1.1-0.81.20.2-0.3
Vertical activity count, locomotor time 10.51.13.9-1.41.3-1.2-1.1-1.62.0-1.91.3-1.5-0.20.60.50.80.30.40.40.61.5-0.6-0.70.00.6-0.3
Time >=10cm from walls, locomotor time 20.30.51.8-0.50.6-0.7-0.7-0.01.0-1.0-0.2-1.30.5-0.3-0.3-0.7-0.5-0.4-0.4-0.80.50.2-0.7-1.30.80.5
Bouts of movement, locomotor time 20.61.04.00.7-0.70.30.10.0-1.01.2-0.11.0-1.30.70.31.00.80.70.71.1-0.7-1.02.01.6-1.8-1.1
Total resting periods, locomotor time 20.61.14.61.1-1.00.70.60.5-1.41.6-0.61.3-0.90.3-0.10.60.40.30.30.7-1.0-0.52.11.3-1.9-1.1
Rest time, locomotor task time 20.50.61.80.9-0.80.50.50.9-0.60.4-0.70.61.3-0.9-0.9-1.0-0.8-0.9-0.8-0.90.01.30.3-0.9-0.10.7
Distance moved, locomotor task time 20.60.71.8-1.41.2-1.0-1.0-1.11.2-1.10.7-1.1-0.20.50.80.80.50.70.60.70.4-0.9-1.00.3-0.10.3
Vertical activity count, locomotor time 20.60.93.2-1.21.2-1.3-1.4-1.11.8-1.60.5-1.50.60.10.10.2-0.1-0.0-0.10.11.1-0.4-1.0-0.5-0.10.5
Light reinforcement 10.10.20.90.2-0.40.70.70.5-0.40.7-0.40.20.3-0.2-0.7-0.4-0.1-0.20.2-0.4-0.80.2-0.2-0.2-0.0-0.9
Light reinforcement 20.40.61.6-0.80.8-0.9-0.8-0.80.30.10.0-0.5-0.80.90.81.20.50.30.81.3-0.4-0.90.71.20.1-0.6
Bone: marrow area0.81.85.1-0.70.3-0.9-0.80.70.30.5-2.1-0.82.3-1.8-1.7-1.7-1.8-1.5-1.7-1.1-0.51.6-1.8-1.80.5-0.2
Bone: maximum diameter1.12.17.0-1.10.8-0.7-0.60.40.60.5-2.6-1.22.6-2.1-2.1-1.7-2.0-1.9-1.7-0.9-0.51.7-0.5-1.8-0.00.1
Bone: maximum force1.83.18.20.5-0.60.60.71.6-0.51.4-2.9-0.12.7-2.5-2.5-2.4-2.4-2.1-2.4-1.8-1.22.30.2-2.1-0.5-1.2
Bone: maximum moment1.93.48.70.4-0.50.50.71.6-0.41.4-3.0-0.12.8-2.5-2.6-2.5-2.6-2.3-2.6-1.8-1.12.40.1-2.2-0.4-1.2
Mean time between licks in bursts0.41.14.40.9-0.91.41.31.0-1.71.70.11.2-1.10.70.60.30.81.00.6-0.0-2.1-1.0-1.10.9-0.2-0.2
Mean num. licks in bursts0.40.62.1-1.01.1-1.1-0.9-1.11.3-1.20.0-0.60.7-0.0-0.60.2-0.20.1-0.40.51.50.50.4-0.20.20.3
Cd content in liver0.40.41.7-0.90.8-0.7-0.6-1.0-0.0-0.3-0.00.6-0.00.60.50.30.50.70.71.2-0.20.30.10.6-1.3-0.1
Co content in liver0.60.72.51.0-1.11.21.40.9-0.80.9-0.40.8-0.3-0.5-0.6-0.8-0.5-0.6-0.5-0.8-0.90.50.2-0.4-0.8-1.6
Cu content in liver1.41.64.42.1-2.02.01.81.2-1.60.91.51.3-1.71.11.10.41.31.10.9-0.7-0.9-1.0-0.00.8-0.11.0
Fe content in liver2.02.48.4-1.91.8-1.8-2.0-0.51.6-0.4-1.2-2.41.6-1.2-1.0-1.0-1.5-1.3-1.1-0.5-0.01.0-2.9-1.42.6-0.0
K content in liver0.10.11.10.5-0.40.20.30.3-0.2-0.00.50.1-0.50.30.30.10.20.20.1-0.20.4-0.0-0.70.10.41.0
Mg content in liver0.10.10.40.6-0.40.10.30.5-0.20.20.0-0.00.2-0.0-0.2-0.3-0.10.1-0.3-0.6-0.00.5-0.4-0.3-0.00.5
Mn content in liver0.50.54.00.2-0.2-0.0-0.1-0.3-0.4-0.10.50.7-0.50.80.90.80.60.50.50.90.5-0.71.01.0-0.72.0
Na content in liver0.30.32.10.0-0.1-0.3-0.4-0.00.4-0.40.7-0.60.20.30.2-0.00.1-0.10.1-0.50.4-0.1-1.2-0.31.41.0
Rb content in liver0.70.91.81.2-1.01.11.11.3-0.80.8-1.00.30.6-0.9-1.1-1.2-0.8-0.8-0.9-1.3-0.31.20.7-1.00.1-0.7
Se content in liver1.82.17.4-0.70.8-0.5-0.6-1.3-0.1-0.31.60.4-1.31.92.11.81.81.81.91.8-0.2-1.7-1.02.0-0.42.7
Sr content in liver1.81.64.51.2-1.21.10.9-0.1-0.80.02.11.3-1.91.51.51.41.71.51.50.50.1-1.60.71.6-0.10.7
Zn content in liver0.10.10.4-0.10.1-0.2-0.1-0.40.0-0.30.60.3-0.50.50.40.30.50.60.30.30.20.1-0.40.3-0.50.6
Bone: minimum diameter0.50.92.50.0-0.30.00.10.6-0.00.7-1.6-0.21.4-1.6-1.4-1.1-1.3-1.3-1.2-0.7-0.31.2-0.1-1.0-0.3-1.1
Time in familiar zone, hab. session 10.50.51.20.6-0.60.40.50.9-0.80.4-0.80.70.6-0.6-0.4-1.0-0.4-0.3-0.4-0.8-0.21.0-0.2-0.9-1.10.9
Time in novel zone, hab. session 10.70.72.1-1.41.4-1.1-1.2-1.11.2-0.40.1-1.50.10.40.00.7-0.1-0.00.20.80.0-0.7-0.90.51.4-0.9
Total zone transitions, hab. session 11.52.14.80.7-0.70.81.0-0.3-1.30.01.91.9-2.21.92.01.22.01.91.81.1-0.4-0.9-0.71.7-1.81.3
Total locomotion distance, hab. session 11.11.53.3-0.20.2-0.30.0-1.0-0.3-0.71.81.1-1.71.61.71.31.81.71.81.40.6-0.9-1.11.5-1.31.2
Locomotion velocity, hab. session 10.81.12.60.3-0.30.20.4-0.6-0.6-0.41.61.2-1.61.21.41.01.61.51.40.90.2-0.6-1.01.2-1.51.2
Time in familiar zone, hab. session 21.01.12.5-0.30.4-0.5-0.7-0.80.1-0.71.3-0.0-1.51.51.61.41.51.41.41.20.1-1.30.01.3-0.50.7
Time in novel zone, hab. session 21.01.02.40.3-0.30.40.50.60.00.6-1.10.11.4-1.5-1.5-1.2-1.4-1.5-1.4-0.9-0.11.5-0.0-1.00.3-1.1
Total zone transitions, hab. session 20.91.22.61.4-1.61.41.61.4-1.20.7-0.41.20.5-0.6-0.8-1.4-0.6-0.9-0.7-1.5-0.91.50.5-1.0-1.1-0.2
Total locomotion distance, hab. session 21.01.42.71.4-1.51.51.61.7-1.31.3-0.80.90.6-1.1-1.0-1.5-1.0-1.3-1.1-1.5-1.01.4-0.2-0.9-0.3-0.1
Locomotion velocity, hab. session 21.21.53.31.6-1.71.71.81.8-1.31.3-0.71.00.6-1.1-0.9-1.6-1.0-1.3-1.1-1.7-0.91.3-0.1-1.1-0.20.2
Novel to familiar place preference ratio1.31.55.0-2.22.2-2.1-1.8-2.01.4-1.20.3-1.00.10.70.40.80.50.90.71.50.7-0.3-1.30.5-0.4-0.2
Novelty place preference2.02.16.7-2.62.5-2.5-2.1-2.41.6-1.50.5-1.1-0.00.90.71.10.71.21.01.90.9-0.5-1.30.7-0.5-0.0
Time in novel zone, NPP test2.32.57.7-2.82.7-2.7-2.3-2.61.8-1.70.6-1.2-0.11.00.81.20.81.31.12.01.1-0.6-1.20.8-0.50.0
Total zone transitions, NPP test0.81.14.31.5-1.31.41.60.7-1.60.51.12.1-1.20.90.9-0.11.00.70.8-0.1-0.70.4-0.00.5-1.40.7
Total locomotion distance, NPP test0.40.61.91.1-1.11.11.41.0-1.20.60.01.3-0.0-0.30.0-0.8-0.1-0.2-0.2-0.8-0.70.8-0.7-0.4-0.7-0.2
Locomotion velocity, NPP test0.60.93.31.5-1.51.51.81.2-1.50.80.21.6-0.5-0.10.2-0.60.2-0.0-0.0-0.7-0.80.6-0.2-0.1-0.7-0.3
Intraocular pressure0.20.31.3-0.50.5-0.8-0.8-0.20.2-0.1-0.8-0.40.8-0.2-0.5-0.2-0.4-0.4-0.30.30.00.40.3-0.2-1.10.4
Delta distance traveled before/after self-admin1.92.04.6-1.91.7-1.8-1.8-1.22.1-2.1-0.2-1.51.7-0.9-0.8-0.8-1.0-1.0-0.8-0.31.71.3-1.5-1.70.51.5
Delta ambulatory time before/after self-admin1.41.73.6-1.71.4-1.4-1.4-0.81.7-1.6-0.7-1.11.9-1.2-1.1-1.2-1.3-1.3-1.0-0.61.01.7-1.4-1.90.11.4
Parametrial fat weight1.33.07.7-2.01.9-1.8-1.7-2.42.4-2.82.1-1.7-1.21.41.71.81.51.71.51.52.6-1.4-1.00.70.6-0.7
Pavlov. Cond. lever latency0.00.00.1-0.30.2-0.2-0.1-0.20.0-0.0-0.3-0.00.3-0.1-0.0-0.1-0.1-0.1-0.10.10.20.20.0-0.1-0.20.4
Pavlov. Cond. magazine entry latency0.91.22.91.7-1.61.51.51.6-1.61.5-0.61.4-0.1-0.5-0.5-0.7-0.4-0.7-0.5-0.9-1.40.40.7-0.1-1.0-0.3
Pavlov. Cond. change in total contacts1.81.94.72.1-2.22.12.01.9-1.81.8-0.81.70.1-0.8-0.7-1.1-0.7-1.0-0.8-1.3-1.50.71.0-0.4-1.2-0.7
Pavlov. Cond. index score0.50.61.41.2-1.11.01.01.2-0.80.8-0.60.70.3-0.7-0.7-0.8-0.6-0.8-0.7-0.9-0.80.50.5-0.5-0.5-0.6
Pavlov. Cond. latency score0.20.30.70.8-0.70.70.60.8-0.50.6-0.30.40.2-0.5-0.5-0.5-0.4-0.6-0.5-0.6-0.70.20.1-0.3-0.3-0.4
Pavlov. Cond. lever contacts0.20.20.91.0-0.90.80.70.8-0.40.30.30.3-0.3-0.2-0.1-0.1-0.0-0.2-0.2-0.6-0.3-0.10.2-0.10.1-0.4
Pavlov. Cond. magazine entry number1.01.23.4-1.81.8-1.6-1.7-1.51.6-1.20.4-1.50.10.30.40.70.40.70.50.91.1-0.4-1.20.21.10.6
Pavlov. Cond. intertrial magazine entries0.20.20.8-0.0-0.20.40.5-0.20.6-0.90.9-0.10.2-0.2-0.1-0.30.10.20.1-0.60.50.5-0.6-0.7-0.3-0.5
Pavlov. Cond. lever-magazine prob. diff.0.40.51.41.2-1.21.01.01.1-0.90.8-0.40.80.1-0.4-0.5-0.6-0.4-0.5-0.5-0.8-0.80.30.7-0.3-0.6-0.6
Pavlov. Cond. response bias0.70.92.81.7-1.71.41.41.5-1.21.0-0.41.0-0.0-0.4-0.5-0.7-0.4-0.7-0.6-1.0-0.80.31.1-0.3-0.7-0.3
Pavlov. Cond. lever latency0.30.42.9-0.20.3-0.20.0-0.4-0.50.1-0.11.1-0.20.60.50.40.60.40.51.0-0.40.70.60.8-1.7-0.3
Pavlov. Cond. magazine entry latency1.01.23.51.6-1.61.91.81.5-0.70.8-0.10.30.4-1.0-0.9-1.2-1.0-1.2-1.0-1.7-0.60.40.6-1.00.7-0.7
Pavlov. Cond. change in total contacts2.13.48.60.2-0.10.30.21.40.70.2-1.8-1.72.7-2.7-2.5-2.5-2.6-2.3-2.5-2.60.21.3-1.3-2.92.2-0.3
Pavlov. Cond. index score0.60.82.80.8-0.81.00.81.00.10.1-0.1-0.60.6-1.1-0.9-1.1-1.1-1.1-1.1-1.70.20.0-0.3-1.41.50.2
Pavlov. Cond. latency score0.70.93.31.0-1.01.21.11.10.10.1-0.0-0.50.7-1.1-1.0-1.2-1.2-1.2-1.2-1.80.20.1-0.2-1.51.30.1
Pavlov. Cond. lever contacts0.30.43.40.1-0.20.2-0.10.30.6-0.30.3-1.20.1-0.5-0.4-0.3-0.5-0.3-0.4-0.90.5-0.9-0.6-0.71.90.2
Pavlov. Cond. magazine entry number0.40.51.7-0.70.7-0.9-0.8-0.8-0.00.0-0.10.3-0.50.60.50.80.70.70.81.2-0.5-0.2-0.01.0-1.3-0.4
Pavlov. Cond. intertrial magazine entries0.30.51.80.2-0.3-0.3-0.30.30.2-0.3-0.80.20.8-0.8-0.7-0.7-0.7-0.7-0.8-0.51.11.31.3-0.9-0.60.4
Pavlov. Cond. lever-magazine prob. diff.0.50.72.30.8-0.81.00.81.00.10.2-0.0-0.60.5-1.0-0.8-1.0-1.0-1.0-1.0-1.50.2-0.1-0.4-1.21.50.2
Pavlov. Cond. response bias0.50.72.80.7-0.80.70.51.10.00.4-0.3-0.70.6-1.1-0.9-1.0-1.0-0.8-1.0-1.50.1-0.1-0.5-1.21.70.2
Time in closed arm before self-admin0.40.53.70.6-0.91.00.80.60.10.40.8-0.6-0.3-0.1-0.1-0.00.0-0.20.0-0.9-0.4-1.0-1.1-0.11.9-0.3
Time in closed arm after self-admin0.30.41.6-0.1-0.20.20.3-0.20.9-0.70.0-0.80.7-0.5-0.5-0.3-0.6-0.6-0.5-0.50.90.31.3-0.71.0-0.3
Time in open arm before self-admin0.30.31.0-0.40.6-0.5-0.5-0.60.4-1.00.80.1-0.10.80.80.60.70.70.70.60.9-0.2-0.20.2-0.20.4
Time in open arm after self-admin0.60.72.0-0.10.4-0.4-0.6-0.5-0.1-0.41.10.3-1.11.31.41.01.00.80.90.80.2-1.1-1.11.0-0.10.7
Bone: periosteal estimation0.81.75.5-0.40.1-0.4-0.20.90.10.8-2.4-0.62.2-2.0-1.8-1.7-1.9-1.6-1.7-1.1-0.61.5-0.7-1.60.1-0.4
Bone: periosteal perimeter1.01.75.6-1.31.1-1.2-1.00.10.80.2-2.4-1.32.2-1.9-1.6-1.3-1.7-1.5-1.4-0.5-0.31.5-0.6-1.5-0.30.3
Bone: post-yield work1.42.04.11.2-1.20.80.91.6-1.31.5-2.01.11.7-1.3-1.9-2.0-1.1-1.2-1.3-1.6-1.51.90.2-1.5-1.7-0.5
Progressive ratio test 1 active lever presses3.54.37.22.5-2.62.22.32.7-2.42.7-2.31.91.4-2.0-1.9-2.2-1.8-1.9-1.9-1.9-2.22.01.9-1.2-1.7-0.8
Progressive ratio test 1 breakpoint3.23.96.62.4-2.52.12.22.6-2.42.5-2.21.91.3-1.8-1.8-2.1-1.7-1.8-1.8-1.9-2.11.91.7-1.2-1.6-0.7
Progressive ratio test 1 inactive lever presses3.65.210.22.9-2.72.52.53.2-2.12.8-2.31.11.7-2.8-2.6-2.5-1.8-2.0-2.0-2.8-2.02.01.9-1.7-0.6-2.4
Progressive ratio test 2 active lever presses2.93.36.82.5-2.31.81.92.2-2.11.9-1.82.11.1-1.7-1.8-1.9-1.5-1.6-1.6-1.5-1.22.22.6-1.0-1.5-0.9
Progressive ratio test 2 breakpoint3.13.67.12.7-2.42.02.02.3-2.32.1-1.82.31.0-1.6-1.8-1.8-1.4-1.6-1.6-1.5-1.42.22.6-0.9-1.7-0.8
Progressive ratio test 2 inactive lever presses1.21.97.12.7-2.21.81.71.9-1.91.5-0.51.8-0.1-0.7-0.9-1.0-0.4-0.6-0.6-1.2-0.91.02.2-0.3-0.9-0.7
Incentive Sensitization - Responses0.20.31.21.0-0.70.50.40.5-0.70.3-0.01.1-0.1-0.2-0.3-0.20.1-0.0-0.1-0.10.20.70.90.1-0.3-0.7
Incentive Sensitization - Breakpoint0.20.31.21.0-0.70.50.40.5-0.70.3-0.21.10.0-0.3-0.5-0.3-0.0-0.1-0.2-0.10.20.81.10.0-0.4-0.7
Sum of active levers in priming session hrs 5-60.10.10.8-0.20.2-0.5-0.3-0.20.2-0.10.0-0.20.0-0.20.10.1-0.00.1-0.10.1-0.2-0.0-0.90.0-0.20.2
Progressive ratio0.20.30.70.4-0.10.20.30.5-0.10.4-0.5-0.30.7-0.4-0.8-0.8-0.8-0.7-0.7-0.8-0.50.6-0.6-0.70.7-0.8
Food seeking constrained by brief footshock0.40.51.70.5-0.60.60.60.6-0.91.2-1.20.60.6-0.4-0.5-0.4-0.5-0.3-0.4-0.1-1.10.51.30.0-0.9-0.4
Seeking ratio, punishment vs. effort0.10.21.60.2-0.40.40.30.3-0.50.5-0.60.50.3-0.4-0.1-0.1-0.2-0.1-0.20.1-0.30.21.30.1-0.90.4
Retroperitoneal fat weight1.14.614.9-3.93.8-3.7-3.7-2.93.3-2.4-1.0-3.21.6-0.1-0.20.9-0.6-0.1-0.22.02.10.10.2-0.20.30.4
Reaction time number correct0.91.74.10.10.2-0.4-0.4-0.8-0.5-0.41.40.9-2.01.92.01.71.81.91.61.60.5-1.30.51.9-1.01.4
Reaction time mean minus median0.10.23.0-0.10.2-0.3-0.60.10.20.1-0.1-0.50.2-0.2-0.1-0.1-0.2-0.3-0.2-0.20.00.5-0.6-0.20.61.7
Reaction time mean minus median AUC0.20.41.3-0.80.9-1.0-1.1-0.60.9-0.60.1-1.00.3-0.1-0.10.3-0.2-0.2-0.10.30.60.3-0.30.00.71.1
Reaction time num false alarms0.20.30.9-0.80.7-0.4-0.4-0.90.6-0.30.6-0.6-0.40.40.40.60.30.20.50.8-0.1-1.0-0.90.6-0.0-0.3
Reaction time num false alarms AUC0.30.41.2-0.80.6-0.3-0.3-0.90.5-0.30.7-0.4-0.60.60.70.80.50.40.60.9-0.2-1.1-0.80.8-0.2-0.6
Reaction time trials correct on left0.91.74.10.10.2-0.4-0.4-0.8-0.5-0.41.40.9-2.01.92.01.71.81.91.61.60.5-1.30.51.9-1.01.4
Reaction time trials on left0.91.84.30.20.1-0.3-0.3-0.7-0.6-0.31.41.0-2.11.92.01.71.91.91.71.60.4-1.30.51.9-1.01.4
Reaction time mean0.30.43.4-0.40.4-0.7-0.90.00.6-0.30.1-1.10.2-0.3-0.2-0.1-0.1-0.0-0.3-0.40.30.2-0.9-0.41.81.1
Reaction time mean AUC0.20.32.3-0.30.4-0.6-0.8-0.00.4-0.30.1-0.80.1-0.2-0.1-0.1-0.00.0-0.2-0.20.40.3-0.6-0.31.51.1
Median of all reaction times0.20.33.2-0.20.2-0.5-0.60.20.3-0.10.0-0.90.1-0.2-0.1-0.1-0.10.0-0.3-0.40.10.1-0.7-0.31.80.8
Reaction time omissions0.71.03.91.3-1.11.00.81.0-2.02.0-0.41.7-0.90.20.40.00.30.10.00.3-1.90.50.31.1-0.60.2
Reaction time false alarm rate0.20.21.7-0.80.5-0.2-0.2-0.60.7-0.10.2-0.80.1-0.1-0.00.2-0.2-0.30.00.2-0.4-0.6-0.80.10.4-1.3
Reaction time premature initiation rate1.52.15.60.5-0.40.40.31.20.01.0-1.6-0.41.8-2.4-2.1-1.8-1.9-2.0-1.9-1.7-0.82.3-0.9-1.61.3-1.1
Reaction time premature initiations0.30.62.60.4-0.1-0.0-0.10.6-0.00.5-0.8-0.10.8-1.4-1.1-0.9-0.9-1.0-1.0-0.7-0.31.6-0.5-0.70.8-0.3
Std. dev. reaction times0.30.62.1-0.91.0-1.1-1.4-0.50.9-0.60.0-1.20.4-0.3-0.20.0-0.2-0.2-0.20.10.60.5-0.8-0.31.41.3
Reaction time trials completed0.91.84.30.20.1-0.3-0.3-0.7-0.6-0.31.41.0-2.11.92.01.71.91.91.71.60.4-1.30.51.9-1.01.4
Reaction time trials AUC0.81.53.3-0.00.3-0.5-0.5-0.8-0.4-0.41.30.8-1.81.71.81.61.71.71.51.60.4-1.20.51.8-0.91.2
Run reversals in cocaine runway, females0.80.81.7-0.81.2-1.0-1.1-1.00.9-1.30.9-0.9-0.50.40.70.71.11.31.20.71.1-0.7-0.80.31.00.5
Run reversals in cocaine runway, males0.40.42.8-0.2-0.10.00.3-0.0-0.3-0.3-0.61.10.8-0.3-0.2-0.7-0.5-0.5-0.5-0.1-0.21.40.6-0.7-1.70.5
Latency to leave start box in cocaine runway0.20.21.3-0.40.7-0.5-0.5-0.0-0.40.6-0.60.0-0.20.30.20.40.10.00.10.6-0.9-0.3-0.70.6-0.01.1
Latency to leave start box in cocaine runway, F0.40.42.60.5-0.30.60.50.9-1.11.2-0.70.5-0.10.1-0.0-0.2-0.1-0.2-0.1-0.2-1.60.1-0.50.2-0.71.0
Latency to leave start box in cocaine runway, M1.11.03.2-1.41.7-1.8-1.7-1.31.0-0.60.2-0.8-0.20.40.51.10.40.30.31.40.8-0.6-0.80.91.20.8
Std. dev. time between licks in bursts0.40.51.40.6-0.61.01.00.9-0.40.4-0.00.10.1-0.4-0.4-0.8-0.5-0.4-0.6-1.1-0.6-0.0-1.2-0.81.2-0.8
Total sessions with >9 infusions3.74.510.71.6-1.81.41.42.3-1.52.3-3.30.92.5-2.6-2.5-2.4-2.7-2.7-2.7-1.9-1.72.42.1-1.8-1.7-1.1
Short access day 1 total inactive lever presses4.45.812.61.2-1.51.41.52.5-0.31.2-2.6-0.53.2-3.2-3.3-3.5-3.2-3.2-3.1-3.5-1.22.8-0.5-3.50.7-1.1
Short access day 10 total inactive lever presses0.71.65.5-1.01.2-1.4-1.4-0.72.1-2.20.2-1.81.3-0.7-0.9-0.6-0.7-0.6-0.6-0.82.30.6-0.2-1.82.2-0.2
Short access day 1 total infusions1.82.44.41.2-1.31.11.01.8-0.61.1-1.90.01.8-2.1-2.0-2.0-2.1-2.1-2.0-2.1-0.71.70.8-1.9-0.4-0.8
Short access day 10 total infusions2.63.37.41.6-1.51.31.32.2-1.52.3-2.70.71.9-2.3-2.2-2.0-2.1-2.1-2.1-1.7-1.61.91.9-1.4-0.8-0.9
Short access total infusions4.55.811.12.3-2.32.02.02.9-2.02.8-3.31.32.4-2.9-2.9-2.7-2.7-2.7-2.7-2.4-2.12.62.4-1.9-1.8-1.0
Short access day 1 locomotion1.11.43.60.6-0.80.70.61.20.10.6-1.1-0.61.4-1.5-1.5-1.5-1.9-1.9-1.9-1.7-0.41.0-0.4-1.50.5-0.5
Short access day 10 total locomotion1.01.94.41.2-1.00.90.61.30.60.3-0.5-1.21.3-1.9-1.8-1.3-1.9-1.9-2.1-2.10.40.60.1-1.61.8-1.7
Short access total locomotion1.82.14.91.1-1.21.10.91.6-0.11.1-1.6-0.51.7-2.1-1.9-1.6-2.2-2.2-2.2-1.9-0.61.10.8-1.50.6-1.4
One hour access (0.3 mA shock)3.84.310.63.3-3.23.03.02.5-3.12.9-1.02.8-0.2-0.4-0.9-1.0-0.5-0.8-0.8-1.2-2.30.73.20.3-2.2-0.8
Compulsive drug intake0.30.31.50.6-0.30.30.4-0.1-0.3-0.80.81.2-0.50.80.60.00.40.20.20.00.90.40.7-0.1-0.10.9
One hour access (shock baseline)1.31.96.11.9-1.91.91.81.8-2.02.5-1.11.20.1-0.7-0.8-0.6-0.4-0.6-0.5-0.8-2.10.11.90.3-1.4-0.9
Social response proportion0.80.96.30.00.20.50.21.0-0.92.1-1.3-0.30.4-0.6-0.5-0.5-0.8-0.7-0.9-0.3-2.50.0-1.70.20.60.6
Social responses0.81.04.50.9-1.01.51.21.2-1.41.6-1.00.80.3-0.9-0.5-1.0-0.7-0.7-0.9-0.7-2.10.6-0.2-0.2-1.0-0.8
Social time1.52.05.72.2-2.32.42.12.0-1.82.1-0.51.1-0.2-1.0-0.5-1.0-0.8-1.0-1.0-1.4-2.40.50.7-0.1-0.7-0.5
Soleus weight0.31.02.80.9-1.00.81.10.40.5-1.00.30.40.9-0.9-1.0-1.1-0.9-1.1-0.9-1.31.31.71.0-1.5-0.4-0.9
Bone: stiffness1.11.84.40.0-0.10.20.21.00.20.8-2.1-0.92.1-1.9-1.9-1.7-2.0-1.8-1.9-1.5-0.71.30.1-1.80.2-0.8
Tibialis anterior weight0.93.010.22.7-2.83.23.21.6-2.42.20.92.1-1.70.40.20.10.70.50.6-0.6-1.6-0.11.41.2-0.8-2.3
Time to tail flick, vehicle, before self-admin0.10.10.6-0.10.1-0.3-0.10.0-0.10.3-0.40.20.4-0.6-0.5-0.4-0.2-0.2-0.1-0.1-0.20.8-0.5-0.3-0.7-0.3
Time to tail flick, vehicle, after self-admin0.60.83.9-1.20.7-0.7-0.5-0.91.5-1.71.1-1.20.0-0.10.2-0.1-0.00.1-0.0-0.21.2-0.1-2.0-0.71.5-0.1
Time to tail flick, test, before self-admin0.50.53.90.4-0.60.80.7-0.1-0.60.40.01.2-0.60.30.30.60.50.40.50.80.10.32.01.0-0.7-1.2
Time to tail flick, test, after self-admin0.30.31.10.1-0.10.00.0-0.30.2-0.60.9-0.1-0.81.11.00.60.70.60.70.20.8-0.90.50.30.40.2
Delta time to tail flick, vehicle, before/after SA0.40.42.20.0-0.30.40.40.50.3-0.0-0.3-0.60.5-0.7-0.6-0.7-0.9-0.9-1.0-0.9-0.20.1-0.8-0.91.50.1
Delta time to tail flick, test, before/after SA0.90.93.0-0.10.1-0.3-0.3-0.60.4-0.91.7-0.6-1.61.41.40.91.21.31.20.20.5-1.7-0.90.60.50.1
Tibia length0.41.13.5-0.30.6-0.7-0.50.4-0.00.2-1.7-0.01.9-1.4-1.4-1.4-1.2-1.0-1.3-0.50.21.70.2-1.3-0.31.7
Ambulatory time before self-admin0.60.93.31.8-1.41.51.41.5-1.41.4-0.20.8-0.4-0.1-0.2-0.4-0.3-0.5-0.5-0.9-1.1-0.20.40.10.4-1.0
Ambulatory time after self-admin0.60.72.30.4-0.40.40.20.70.10.0-0.2-0.20.7-0.8-0.8-1.3-1.1-1.4-1.1-1.3-0.50.9-1.5-1.30.50.5
Bone: tissue strength0.20.20.7-0.70.8-0.8-0.5-0.50.5-0.5-0.2-0.50.40.1-0.1-0.0-0.3-0.2-0.20.30.40.20.4-0.20.1-0.1
Total heroin consumption1.11.34.41.1-1.41.21.41.0-1.51.6-1.21.80.4-0.8-0.7-0.8-0.6-0.7-0.8-0.3-1.51.21.1-0.0-2.1-0.5
Bone: trabecular number0.20.41.2-0.60.6-0.6-0.6-0.70.4-0.60.6-0.1-0.50.80.70.70.81.10.80.70.2-0.1-0.80.6-0.30.3
Bone: trabecular spacing1.62.14.40.6-0.60.20.41.2-0.20.5-2.1-0.22.1-1.9-1.9-2.0-2.0-2.1-1.8-1.60.12.01.5-2.0-0.2-1.0
Bone: trabecular thickness0.70.92.3-0.30.3-0.4-0.6-0.80.6-0.71.5-0.4-1.41.11.31.51.11.11.10.80.5-1.3-0.31.20.60.1
Bone: trabecular tissue density0.50.73.0-0.40.30.30.3-0.60.8-0.81.7-1.0-1.01.00.80.90.90.90.90.10.2-1.3-0.80.51.1-0.9
Water consumed over 24 hours0.20.30.8-0.1-0.10.40.6-0.20.5-0.60.10.20.6-0.6-0.6-0.6-0.7-0.9-0.7-0.50.50.7-0.2-0.8-0.5-0.5
Number of responses in last shaping day4.65.111.23.0-2.82.92.73.2-2.43.4-2.11.31.0-2.1-2.1-2.0-1.9-2.1-2.2-2.3-2.81.41.5-0.9-0.8-2.2