Hub : Genes

Ets2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Ets2 0.37 0.13 0.0e+00 0.23 0.23 0.22 0.23 2.1e-25 4.3e-25 1.4e-24 5.1e-25
2 PL gene expression Ets2 0.29 0.11 0.0e+00 0.18 0.18 0.2 0.19 3.4e-19 2.9e-19 3.8e-21 1.4e-20
3 NAcc mRNA stability Ets2 0.12 0.1 2.0e-06 0.05 0.05 0.05 0.04 2.8e-06 3.4e-06 1.8e-06 9.9e-06
4 IL gene expression Ets2 0.42 0.18 9.4e-05 0.13 0.2 0.24 0.25 4.2e-04 1.9e-05 1.8e-06 9.4e-07
5 NAcc gene expression Ets2 0.15 0.08 1.3e-11 0.07 0.09 0.1 0.09 4.3e-08 6.0e-11 2.4e-11 1.0e-10
6 OFC gene expression Ets2 0.5 0.16 4.2e-07 0.18 0.15 0.23 0.15 4.4e-05 1.8e-04 3.7e-06 1.7e-04
7 Brain mRNA stability Ets2 0.03 0.02 4.1e-03 0.02 0.01 0.01 0.01 5.3e-03 5.2e-02 2.8e-02 2.4e-02
8 Adipose mRNA stability Ets2 0.14 0.08 3.8e-09 0.06 0.04 0.05 0.05 1.5e-07 3.5e-05 2.7e-06 1.5e-06
9 BLA gene expression Ets2 0.17 0.09 3.4e-05 0.08 0.08 0.08 0.07 2.9e-05 4.6e-05 5.3e-05 1.0e-04
10 Eye gene expression Ets2 0.37 0.18 5.1e-03 0.1 0.07 0.03 0.1 1.2e-02 3.3e-02 1.1e-01 1.4e-02
11 Brain gene expression Ets2 0.38 0.14 0.0e+00 0.19 0.28 0.27 0.27 1.5e-17 1.3e-25 3.8e-25 4.9e-25
12 Liver gene expression Ets2 0.11 0.06 1.9e-09 0.03 0.07 0.07 0.07 6.6e-04 1.1e-08 3.9e-08 1.5e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.10.10.40.40.00.4-0.10.00.20.3-0.40.40.6-0.30.1
Area under the delay curve0.20.21.40.0-0.00.2-0.0-0.6-0.30.3-0.20.20.20.01.2
BMI with tail0.10.31.00.0-0.10.60.0-0.5-0.20.5-0.40.40.8-0.21.0
BMI without tail0.30.61.40.7-1.20.11.1-1.2-1.0-0.40.4-0.4-0.20.80.2
Body weight0.00.10.30.20.10.2-0.2-0.00.10.5-0.20.20.5-0.30.5
Weight adjusted by age3.84.36.10.3-2.3-1.52.3-2.1-2.3-2.32.5-2.5-2.02.4-1.4
Bone surface1.22.14.9-0.82.2-0.2-2.01.61.91.3-1.11.11.3-1.70.9
Bone volume1.11.93.5-0.21.90.3-1.81.41.71.4-1.21.21.5-1.60.9
Breakpoint value in progressive ratio session3.33.610.9-3.00.1-3.30.8-0.3-0.0-2.22.2-2.2-1.80.8-2.3
Number of licking bursts0.30.30.90.8-0.60.90.3-0.6-0.60.3-0.20.2-0.20.30.8
Context. condit. distance diff. score0.20.31.1-1.00.5-0.7-0.50.60.4-0.30.3-0.3-0.1-0.3-0.7
Locomotion velocity, session 10.80.91.71.30.81.0-1.11.20.91.1-0.80.80.8-0.60.3
Locomotion distance, session 12.02.65.40.42.20.7-2.22.32.11.7-1.41.41.3-1.70.3
Locomotion velocity, session 20.30.40.9-0.90.8-1.0-0.60.80.7-0.10.3-0.3-0.4-0.3-0.7
Locomotion distance, session 20.20.30.90.00.9-0.1-0.80.70.70.5-0.20.20.1-0.50.4
Locomotion velocity, session 33.33.98.2-0.02.50.8-2.52.92.62.1-1.81.81.6-2.30.1
Locomotion distance, session 30.20.20.6-0.50.0-0.70.1-0.0-0.1-0.40.6-0.6-0.70.4-0.4
Stereotopy head waving bouts, day 32.73.27.72.80.42.7-0.91.00.82.2-2.22.22.0-1.21.1
Stereotopy head waving duration, day 33.23.88.32.80.62.9-1.21.21.02.3-2.42.42.3-1.41.3
Locomotion velocity, session 71.51.62.3-0.9-1.2-1.21.3-1.2-1.1-1.41.5-1.5-1.31.2-1.2
Locomotion distance, session 74.15.27.1-2.0-2.0-2.32.4-2.5-2.2-2.72.6-2.6-2.32.2-1.3
Stereotopy head waving bouts, day 72.52.85.40.71.71.3-1.92.32.01.8-1.81.81.7-1.9-0.1
Stereotopy head waving duration, day 72.93.58.5-0.02.30.8-2.42.92.51.8-1.61.61.6-2.2-0.3
Locomotion velocity, session 81.72.14.6-0.11.80.8-1.92.11.81.4-1.41.41.0-1.70.1
Locomotion distance, session 80.30.41.0-0.91.0-0.7-0.80.80.70.00.1-0.1-0.1-0.5-0.2
Degree of sensitization distance1.11.12.3-0.5-1.4-0.61.4-1.5-1.2-1.20.9-0.9-0.61.0-0.5
Degree of sensitization stereotypy2.62.86.2-0.52.20.4-2.22.52.31.5-1.41.41.3-2.1-0.1
Conditioned locomotion0.60.71.1-0.4-0.6-0.90.7-0.3-0.5-1.01.1-1.1-1.00.8-1.0
Cocaine response after cond. corrected0.60.61.6-1.01.2-0.6-0.91.31.10.40.0-0.0-0.3-0.8-0.5
Cocaine response after cond. not corrected0.70.72.4-1.50.9-1.2-0.50.90.8-0.20.6-0.6-0.9-0.4-0.9
Cocaine response before conditioning0.10.10.5-0.70.0-0.50.1-0.3-0.2-0.30.4-0.4-0.40.20.2
Saline control response0.60.82.2-0.51.0-0.5-0.91.51.30.4-0.30.30.5-0.9-1.1
Bone: connectivity density0.20.30.7-0.20.80.0-0.70.40.70.5-0.60.60.8-0.70.5
Bone: cortical apparent density1.11.52.20.51.11.2-1.31.01.11.4-1.41.41.5-1.31.1
Bone: cortical area0.30.51.6-1.20.6-1.3-0.30.60.5-0.40.7-0.7-0.6-0.0-0.8
Bone: cortical porosity0.40.41.31.10.11.0-0.40.20.10.7-0.80.80.5-0.30.6
Bone: cortical porosity0.20.31.01.00.00.8-0.30.1-0.10.5-0.50.50.2-0.10.7
Bone: cortical thickness1.01.72.9-1.1-0.7-1.61.0-0.4-0.6-1.51.7-1.7-1.61.2-1.7
Bone: cortical thickness0.60.71.2-0.5-0.6-1.00.8-0.7-0.6-1.01.1-1.1-0.90.9-0.8
Bone: cortical tissue density1.31.72.60.61.21.3-1.41.11.11.5-1.51.51.6-1.41.2
Condit. Reinf. active minus inactive responses0.10.10.30.1-0.4-0.40.5-0.4-0.3-0.30.3-0.3-0.50.4-0.3
Condit. Reinf. active-inactive response ratio0.80.91.8-0.0-1.0-0.81.1-0.6-0.7-0.91.1-1.1-1.11.1-1.3
Condit. Reinf. active responses0.10.20.4-0.30.6-0.2-0.40.40.50.4-0.40.40.1-0.50.4
Condit. Reinf. inactive responses1.41.72.9-0.41.70.4-1.61.41.51.2-1.41.41.1-1.60.9
Incentive salience index mean0.40.51.1-0.3-0.6-0.80.8-0.7-0.7-0.70.8-0.8-1.10.8-0.2
Condit. Reinf. lever presses0.30.41.1-0.6-0.4-0.70.6-0.6-0.5-0.60.6-0.6-1.10.6-0.1
Condit. Reinf. active minus inactive responses0.50.71.3-1.01.2-0.4-0.90.81.10.3-0.70.70.7-1.10.3
Condit. Reinf. active-inactive response ratio0.20.21.40.6-0.20.50.1-0.6-0.40.1-0.30.30.20.11.2
Condit. Reinf. active responses0.91.32.8-1.31.4-0.5-1.11.61.70.4-0.70.70.9-1.4-0.7
Condit. Reinf. inactive responses1.31.63.7-1.71.4-0.8-1.11.91.80.3-0.30.30.7-1.3-1.6
Condit. Reinf. lever presses0.60.84.1-2.00.2-1.60.4-0.10.2-0.80.7-0.7-0.80.0-0.7
Condit. Reinf. lever reinforcers received0.81.12.5-1.41.4-0.6-1.01.51.60.3-0.60.60.7-1.3-0.6
Conditioned reinforcement - actives0.30.30.7-0.70.90.1-0.70.60.60.50.3-0.3-0.6-0.50.4
Conditioned reinforcement - inactives1.31.54.6-1.5-0.3-1.20.7-0.2-0.3-1.21.6-1.6-2.20.6-1.4
Conditioned locomotion0.30.31.1-1.00.3-1.00.00.30.4-0.50.2-0.2-0.4-0.1-0.8
Patch foraging indifference point 0 sec2.43.89.0-1.2-1.7-2.22.0-1.1-1.2-2.12.3-2.3-1.81.7-3.0
Patch foraging indifference point AUC1.61.84.9-1.01.9-0.9-1.62.22.00.5-0.40.40.4-1.4-1.2
Delay disc. indifference point, 0s delay0.40.52.1-0.00.50.1-0.5-0.10.30.6-0.70.71.5-0.61.1
Delay disc. indifference point, 16s delay0.40.41.40.8-0.00.9-0.2-0.3-0.20.7-0.60.60.5-0.11.2
Delay disc. indifference point, 2s delay0.40.41.90.30.10.6-0.1-0.5-0.10.6-0.90.90.6-0.21.4
Delay disc. indifference point, 24s delay0.30.32.10.40.10.3-0.0-0.6-0.40.30.1-0.1-0.40.21.4
Delay disc. indifference point, 4s delay0.20.21.30.00.20.3-0.2-0.30.10.5-0.50.50.6-0.31.1
Delay disc. indifference point, 8s delay0.20.20.6-0.1-0.3-0.10.3-0.8-0.6-0.20.4-0.4-0.50.40.7
Indifference point function ln k0.50.61.2-0.0-1.1-0.20.9-1.1-1.1-0.70.9-0.9-0.61.0-0.0
Indifference point function log k0.50.61.2-0.0-1.1-0.20.9-1.1-1.1-0.70.9-0.9-0.61.0-0.0
Patch foraging total patch changes 0 sec2.13.39.3-1.2-1.5-2.11.8-0.8-1.0-2.02.1-2.1-1.51.5-3.0
Patch foraging total patch changes 12 sec1.11.46.9-1.20.5-1.70.01.00.8-0.81.1-1.1-0.4-0.1-2.6
Patch foraging total patch changes 18 sec1.01.33.1-1.21.4-1.0-1.01.81.70.4-0.50.50.5-1.2-1.5
Patch foraging total patch changes 24 sec0.30.31.3-1.10.6-0.9-0.20.50.6-0.20.1-0.10.1-0.3-0.9
Patch foraging total patch changes 6 sec0.81.26.9-1.10.5-1.5-0.11.21.0-0.50.7-0.7-0.4-0.4-2.6
Patch foraging time to switch 0 sec1.01.54.31.50.22.0-0.6-0.00.11.4-1.31.31.1-0.52.1
Patch foraging water rate 0 sec0.40.72.9-1.30.4-1.3-0.10.60.7-0.60.1-0.10.4-0.4-1.7
Patch foraging water rate 12 sec0.91.42.2-1.3-1.1-1.31.3-0.9-0.8-1.31.2-1.2-1.41.0-1.5
Patch foraging water rate 18 sec0.20.30.90.0-0.8-0.20.8-0.9-0.8-0.60.4-0.40.00.7-0.0
Patch foraging water rate 24 sec2.53.55.9-2.3-0.9-2.41.6-1.4-1.1-2.32.4-2.4-1.81.4-1.5
Patch foraging water rate 6 sec0.30.51.5-1.2-0.4-0.80.6-0.8-0.6-1.00.3-0.3-0.60.6-0.2
Seeking ratio, delayed vs. immediate footshock0.91.02.01.20.11.4-0.5-0.00.21.0-1.31.31.4-0.61.3
Distance traveled before self-admin0.10.10.7-0.40.1-0.20.00.30.1-0.10.3-0.3-0.8-0.0-0.2
Distance traveled after self-admin1.51.63.00.6-1.7-0.21.6-1.7-1.7-1.11.3-1.3-0.81.5-0.2
Extensor digitorum longus weight3.915.221.31.83.73.4-4.03.43.74.6-4.64.64.4-4.33.2
Bone: elastic displacement0.40.53.11.8-0.61.20.1-0.2-0.40.6-0.20.20.40.40.3
Bone: elastic work0.40.62.31.5-0.01.3-0.40.30.11.0-0.70.70.8-0.20.4
Bone: endosteal estimation0.92.03.10.41.60.8-1.71.11.31.6-1.51.51.6-1.51.7
Bone: endosteal perimeter1.02.14.8-1.02.2-0.2-2.01.92.01.3-1.01.01.1-1.80.5
Epididymis fat weight0.92.14.6-0.61.8-0.1-1.51.01.61.5-1.31.32.2-1.71.5
Delta time in closed arm before/after self-admin0.80.82.71.6-0.31.7-0.1-0.5-0.50.9-0.60.60.20.11.3
Delta time in open arm before/after self-admin0.50.50.9-0.7-0.6-0.70.8-0.7-0.7-0.91.0-1.0-0.20.7-0.2
Diff in mean of infusions in LGA sessions1.61.84.9-2.21.6-1.9-1.11.61.6-0.5-0.10.1-0.0-1.0-1.6
Delay discount exponential model param0.20.21.4-0.1-0.1-0.30.10.50.1-0.40.4-0.4-0.20.1-1.2
Extinction: sum of active levers before priming3.03.07.3-2.7-0.2-2.71.2-0.3-0.1-2.21.9-1.9-1.20.8-2.5
Active lever presses in extinction session 60.90.83.4-0.2-1.1-0.61.2-0.3-0.5-1.00.7-0.7-0.80.7-1.8
Bone: final force0.10.20.7-0.80.1-0.7-0.00.30.1-0.30.6-0.6-0.30.1-0.8
Bone: final moment0.20.31.2-1.10.2-0.9-0.10.30.2-0.40.6-0.6-0.40.0-0.9
Food consumed during 24 hour testing period0.20.30.50.40.50.5-0.60.70.40.7-0.50.50.1-0.40.4
Glucose2.23.36.2-0.52.50.2-2.22.42.51.7-1.61.61.8-2.20.3
Heart weight0.30.41.70.8-0.10.7-0.1-0.4-0.10.5-0.60.60.3-0.21.3
Delay discount hyperbolic model param0.20.31.7-0.2-0.1-0.40.20.40.1-0.50.5-0.5-0.40.2-1.3
Intermittent access intake day 1-15 change0.10.10.6-0.6-0.10.20.10.30.2-0.00.1-0.1-0.1-0.3-0.8
Intermittent access intake escalation0.20.20.7-0.70.00.4-0.00.50.30.10.1-0.1-0.1-0.4-0.8
Intermittent access intake escalation 20.30.31.1-0.90.30.1-0.30.80.60.20.2-0.20.1-0.5-1.1
Intermitt. access day 1 inactive lever presses1.21.35.7-0.8-0.3-0.90.40.0-0.4-1.11.5-1.5-2.40.8-1.3
Intermitt. access day 15 inactive lever presses0.80.94.5-1.60.4-1.20.20.20.1-0.70.7-0.7-2.10.2-0.5
Intermitt. access escalation Index0.40.30.7-0.5-0.5-0.40.8-0.6-0.5-0.80.2-0.2-0.70.6-0.1
Intermittent access day 1 total infusions0.60.73.3-1.80.4-1.80.2-0.20.2-1.00.4-0.4-0.40.1-0.6
Intermittent access day 15 total infusions0.60.73.3-1.80.2-1.10.20.40.4-0.70.5-0.5-0.6-0.2-1.4
Intermittent access terminal intake (last 3 days)0.80.93.6-1.9-0.1-1.30.5-0.1-0.0-0.90.9-0.9-1.00.2-1.2
Intermittent access total infusions1.21.35.0-2.2-0.1-1.80.6-0.3-0.1-1.31.0-1.0-1.10.4-1.2
Intermittent access day 1 locomotion1.11.24.7-2.10.1-2.20.5-0.5-0.1-1.40.8-0.8-0.80.5-0.7
Intermittent access day 15 total locomotion1.31.46.3-2.50.9-2.2-0.10.61.0-1.00.2-0.20.2-0.6-1.5
Intermittent access total locomotion2.12.39.6-3.10.8-2.80.10.40.8-1.51.1-1.1-1.1-0.2-1.8
Intermittent access standard deviation0.10.10.8-0.1-0.00.0-0.10.40.2-0.00.1-0.1-0.3-0.1-0.9
Left kidney weight0.71.94.0-0.9-0.9-1.31.1-1.5-1.3-1.31.9-1.9-2.01.3-0.1
Right kidney weight0.82.34.9-1.0-1.0-1.41.1-1.5-1.5-1.32.1-2.1-2.21.50.1
Cocaine induced anxiety0.50.53.1-1.70.5-1.10.00.60.7-0.30.0-0.0-0.5-0.4-0.9
Post-drug Anxiety0.80.93.7-1.91.2-1.2-0.61.11.2-0.10.1-0.1-0.5-0.8-0.7
Baseline Anxiety0.10.10.50.7-0.20.40.0-0.3-0.30.00.4-0.4-0.00.30.3
Tail length0.51.53.0-0.2-0.9-1.41.2-0.6-0.8-1.31.5-1.5-1.71.2-1.4
Length with tail0.00.10.4-0.00.2-0.4-0.10.30.1-0.00.4-0.4-0.60.1-0.4
Length without tail0.10.20.7-0.30.80.1-0.80.70.60.5-0.20.20.3-0.50.2
Times rat made contact with spout1.01.22.30.4-1.4-0.11.2-1.1-1.4-0.91.1-1.1-1.51.4-0.6
Lifetime Intake0.70.83.2-1.8-0.3-1.30.8-0.7-0.4-1.00.6-0.6-0.80.5-0.7
Liver weight, left0.30.51.7-1.0-0.0-1.30.4-0.4-0.2-0.80.9-0.9-0.70.4-0.4
Liver weight, right0.20.30.6-0.3-0.3-0.70.4-0.6-0.5-0.80.7-0.7-0.30.5-0.3
Locomotor activity3.96.29.9-1.2-2.4-1.92.7-2.4-2.5-2.73.1-3.1-2.52.6-1.8
Locomotor testing distance1.72.84.0-0.8-1.8-1.42.0-1.6-1.6-1.91.9-1.9-1.61.7-1.5
Locomotor testing rearing0.81.32.2-1.4-0.7-1.20.9-1.0-0.9-1.31.5-1.5-1.20.9-0.5
Locomotion in novel chamber0.20.20.50.40.70.2-0.70.50.40.6-0.30.3-0.2-0.40.5
Locomotion in novel chamber post-restriction2.32.84.81.80.72.0-1.10.50.82.0-2.12.12.2-1.32.0
Fecal boli incidents, locomotor time 10.50.51.2-0.5-0.5-0.30.5-1.1-0.9-0.40.9-0.9-0.60.60.7
Change in fecal boli incidents, locomotor task0.50.51.40.9-0.70.80.4-0.9-0.80.3-0.40.4-0.30.51.2
Time >=10cm from walls, locomotor time 10.20.20.5-0.3-0.4-0.30.5-0.6-0.6-0.40.3-0.3-0.70.50.2
Bouts of movement, locomotor time 11.31.42.60.71.31.2-1.61.61.41.5-0.90.90.8-1.40.3
Total resting periods, locomotor time 10.80.92.20.51.20.8-1.41.51.31.1-0.50.50.2-1.1-0.0
Rest time, locomotor task time 10.20.20.8-0.90.8-0.5-0.60.20.40.0-0.20.2-0.1-0.50.4
Distance moved, locomotor task time 10.60.61.81.0-1.30.41.1-0.9-1.0-0.50.3-0.3-0.21.0-0.4
Vertical activity count, locomotor time 10.10.10.30.3-0.5-0.00.4-0.1-0.2-0.20.2-0.20.30.3-0.5
Time >=10cm from walls, locomotor time 20.20.30.70.7-0.50.50.2-0.6-0.6-0.0-0.30.30.60.20.8
Bouts of movement, locomotor time 21.31.45.3-2.31.7-1.5-1.00.91.5-0.1-0.40.40.6-1.2-0.1
Total resting periods, locomotor time 20.90.95.0-2.21.1-1.6-0.50.30.9-0.50.0-0.00.1-0.7-0.3
Rest time, locomotor task time 20.30.30.8-0.50.9-0.0-0.80.60.70.5-0.20.20.1-0.60.4
Distance moved, locomotor task time 20.20.20.80.9-0.70.40.5-0.4-0.4-0.2-0.10.10.30.4-0.2
Vertical activity count, locomotor time 20.30.30.50.3-0.7-0.20.7-0.7-0.7-0.70.3-0.3-0.20.7-0.1
Light reinforcement 10.20.32.30.4-0.10.20.1-0.6-0.60.1-0.30.3-0.20.41.5
Light reinforcement 21.52.05.8-1.42.4-0.7-2.01.62.00.9-0.70.70.7-1.60.9
Bone: marrow area1.02.23.50.31.80.8-1.91.21.41.7-1.61.61.7-1.61.8
Bone: maximum diameter0.61.12.9-1.01.7-0.6-1.51.51.50.6-0.40.40.4-1.1-0.1
Bone: maximum force0.10.10.5-0.50.3-0.2-0.20.60.40.00.0-0.00.2-0.3-0.7
Bone: maximum moment0.10.20.7-0.80.3-0.5-0.20.50.4-0.10.2-0.2-0.0-0.3-0.8
Mean time between licks in bursts0.91.33.31.8-1.70.81.4-1.4-1.6-0.40.3-0.3-0.51.30.3
Mean num. licks in bursts0.20.31.5-0.4-0.1-0.70.20.30.1-0.50.5-0.5-0.40.2-1.2
Cd content in liver2.02.24.8-0.2-2.2-0.62.2-1.6-1.6-1.51.2-1.2-1.41.5-1.4
Co content in liver0.30.31.90.30.10.6-0.2-0.4-0.10.6-0.60.60.4-0.31.4
Cu content in liver0.20.20.6-0.7-0.1-0.60.2-0.1-0.0-0.50.5-0.5-0.50.1-0.5
Fe content in liver0.10.10.40.7-0.30.60.20.2-0.00.2-0.30.3-0.0-0.0-0.4
K content in liver0.40.40.6-0.0-0.7-0.40.8-0.8-0.7-0.60.7-0.7-0.60.7-0.2
Mg content in liver0.10.10.20.4-0.40.30.4-0.2-0.20.0-0.10.10.20.1-0.2
Mn content in liver1.11.22.2-0.41.50.2-1.30.91.21.0-1.11.11.1-1.31.3
Na content in liver1.21.33.2-1.21.8-0.7-1.41.61.70.4-0.50.50.4-1.3-0.3
Rb content in liver0.20.30.50.5-0.70.10.6-0.6-0.7-0.40.4-0.4-0.40.7-0.0
Se content in liver0.40.51.00.1-0.9-0.31.0-0.5-0.7-0.50.6-0.6-1.00.8-0.9
Sr content in liver1.21.11.6-0.3-1.0-0.71.1-1.2-1.2-1.11.2-1.2-1.21.2-0.4
Zn content in liver0.60.71.5-0.4-0.8-0.61.0-0.7-0.7-0.80.9-0.9-1.20.7-0.7
Bone: minimum diameter2.34.26.10.52.31.2-2.52.22.32.2-2.22.22.4-2.41.2
Time in familiar zone, hab. session 11.21.12.00.11.30.7-1.41.11.11.2-1.11.10.9-1.21.0
Time in novel zone, hab. session 10.50.51.21.1-1.10.70.9-0.9-0.9-0.20.1-0.10.20.70.1
Total zone transitions, hab. session 11.52.24.4-1.3-0.8-1.91.1-1.1-1.2-1.81.8-1.8-2.11.4-0.8
Total locomotion distance, hab. session 11.42.02.8-0.5-1.2-1.51.4-1.5-1.5-1.61.7-1.7-1.61.7-0.7
Locomotion velocity, hab. session 11.72.33.4-0.8-1.2-1.71.5-1.4-1.4-1.81.8-1.8-1.81.7-1.0
Time in familiar zone, hab. session 21.21.21.80.31.20.9-1.30.91.01.2-1.21.21.3-1.21.2
Time in novel zone, hab. session 21.01.01.60.1-1.2-0.61.3-0.9-1.0-1.11.0-1.0-0.71.2-1.0
Total zone transitions, hab. session 20.30.31.0-0.6-0.0-1.00.2-0.3-0.2-0.60.7-0.7-0.70.5-0.3
Total locomotion distance, hab. session 20.81.01.5-0.3-0.8-1.21.0-0.9-0.9-1.11.2-1.2-0.91.2-0.8
Locomotion velocity, hab. session 20.81.01.7-0.5-0.8-1.31.0-0.8-0.8-1.21.3-1.3-1.01.2-0.9
Novel to familiar place preference ratio0.90.91.60.4-1.1-0.41.1-1.2-1.1-1.10.9-0.9-0.91.2-0.3
Novelty place preference0.50.51.10.5-0.9-0.20.8-1.1-1.0-0.80.6-0.6-0.51.00.1
Time in novel zone, NPP test0.40.40.90.7-0.7-0.00.7-1.0-0.8-0.60.4-0.4-0.30.80.3
Total zone transitions, NPP test0.20.30.9-0.51.0-0.3-0.81.00.80.3-0.10.1-0.0-0.5-0.2
Total locomotion distance, NPP test0.10.10.10.2-0.0-0.40.1-0.1-0.2-0.20.4-0.4-0.30.4-0.2
Locomotion velocity, NPP test0.10.10.3-0.0-0.0-0.60.2-0.0-0.1-0.40.6-0.6-0.50.4-0.4
Intraocular pressure1.41.95.42.3-0.12.1-0.5-0.0-0.21.3-1.51.51.9-0.41.5
Delta distance traveled before/after self-admin1.81.94.50.5-1.7-0.31.6-2.1-1.9-1.31.4-1.4-0.71.70.1
Delta ambulatory time before/after self-admin2.22.55.50.4-1.9-0.51.9-2.3-2.1-1.61.6-1.6-0.82.0-0.1
Parametrial fat weight0.71.32.61.10.71.6-0.80.10.61.3-1.21.21.6-0.91.6
Pavlov. Cond. lever latency0.10.20.60.7-0.60.50.4-0.5-0.4-0.0-0.10.10.50.30.0
Pavlov. Cond. magazine entry latency0.20.30.90.5-0.90.20.7-0.9-0.9-0.30.1-0.1-0.20.60.4
Pavlov. Cond. change in total contacts0.20.20.5-0.60.7-0.6-0.40.10.30.0-0.10.1-0.4-0.20.7
Pavlov. Cond. index score0.20.20.8-0.5-0.2-0.50.4-0.4-0.4-0.40.5-0.5-0.90.50.1
Pavlov. Cond. latency score0.40.41.3-0.7-0.3-0.80.5-0.6-0.6-0.70.7-0.7-1.10.7-0.0
Pavlov. Cond. lever contacts0.70.82.7-1.60.4-1.50.10.20.2-0.80.8-0.8-1.20.2-0.8
Pavlov. Cond. magazine entry number0.10.10.4-0.60.5-0.4-0.30.50.4-0.10.2-0.20.0-0.2-0.5
Pavlov. Cond. intertrial magazine entries2.42.96.5-0.11.90.7-1.92.62.31.5-1.61.61.7-2.1-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.20.7-0.4-0.2-0.40.3-0.4-0.4-0.30.4-0.4-0.80.40.1
Pavlov. Cond. response bias0.00.10.10.10.20.2-0.20.20.20.3-0.40.40.0-0.20.3
Pavlov. Cond. lever latency0.81.12.91.6-1.70.61.2-1.3-1.4-0.60.5-0.5-0.11.3-0.4
Pavlov. Cond. magazine entry latency0.50.51.9-1.40.3-1.30.1-0.00.1-0.70.8-0.8-0.90.2-0.4
Pavlov. Cond. change in total contacts0.81.12.8-1.21.7-0.4-1.41.11.30.7-0.60.60.4-1.30.8
Pavlov. Cond. index score0.40.52.0-1.41.0-0.9-0.60.70.80.00.2-0.2-0.5-0.6-0.2
Pavlov. Cond. latency score0.30.41.9-1.40.7-1.1-0.30.40.5-0.20.4-0.4-0.8-0.2-0.1
Pavlov. Cond. lever contacts0.50.71.8-1.31.3-0.6-0.90.81.00.5-0.40.4-0.0-0.90.5
Pavlov. Cond. magazine entry number0.10.10.40.2-0.6-0.00.6-0.3-0.4-0.40.1-0.1-0.00.3-0.6
Pavlov. Cond. intertrial magazine entries0.30.41.0-0.30.40.1-0.50.80.80.2-0.50.51.0-0.7-0.9
Pavlov. Cond. lever-magazine prob. diff.0.40.62.3-1.51.0-1.0-0.60.70.8-0.00.2-0.2-0.5-0.6-0.2
Pavlov. Cond. response bias0.50.71.8-1.31.4-0.5-1.01.01.10.5-0.40.40.1-1.00.4
Time in closed arm before self-admin1.31.43.10.21.60.8-1.81.41.31.4-1.01.00.3-1.31.2
Time in closed arm after self-admin3.63.79.82.31.12.8-1.80.50.62.6-2.02.00.9-1.23.1
Time in open arm before self-admin0.80.81.90.4-1.3-0.21.4-1.3-1.3-0.90.5-0.50.11.1-0.3
Time in open arm after self-admin1.31.53.0-1.7-0.7-1.71.2-0.5-0.4-1.61.3-1.30.10.8-1.5
Bone: periosteal estimation0.40.92.3-0.41.5-0.2-1.41.21.20.9-0.60.60.7-1.00.5
Bone: periosteal perimeter1.01.63.9-1.02.0-0.5-1.71.91.90.9-0.60.60.7-1.4-0.3
Bone: post-yield work0.60.81.4-0.40.90.3-0.81.11.20.6-1.11.11.0-1.2-0.2
Progressive ratio test 1 active lever presses0.50.51.7-1.3-0.2-1.10.4-0.7-0.4-0.80.5-0.5-0.80.4-0.2
Progressive ratio test 1 breakpoint0.70.81.4-1.0-0.7-1.00.8-1.2-0.9-1.00.8-0.8-1.10.80.0
Progressive ratio test 1 inactive lever presses0.91.03.0-1.3-0.6-1.10.7-0.5-0.6-1.20.9-0.9-1.70.7-1.2
Progressive ratio test 2 active lever presses0.30.31.3-1.10.0-0.80.20.30.3-0.50.4-0.4-0.4-0.1-1.1
Progressive ratio test 2 breakpoint0.40.51.7-1.2-0.2-1.00.50.10.1-0.70.5-0.5-0.50.1-1.3
Progressive ratio test 2 inactive lever presses1.82.18.3-2.90.6-1.90.00.80.7-1.11.2-1.2-1.8-0.2-1.9
Incentive Sensitization - Responses0.50.52.0-1.10.4-0.8-0.10.90.8-0.20.3-0.30.3-0.5-1.4
Incentive Sensitization - Breakpoint0.50.51.9-1.10.6-0.7-0.31.00.9-0.10.2-0.20.4-0.6-1.4
Sum of active levers in priming session hrs 5-63.93.812.1-2.4-0.5-3.11.3-0.2-0.0-2.42.0-2.0-1.30.8-3.5
Progressive ratio0.30.30.50.20.60.5-0.70.50.50.6-0.50.50.5-0.50.6
Food seeking constrained by brief footshock1.31.63.5-0.1-1.3-0.61.2-1.1-1.4-1.31.5-1.5-1.91.5-0.6
Seeking ratio, punishment vs. effort1.51.92.90.3-1.7-0.51.6-1.4-1.6-1.31.5-1.5-1.71.6-0.8
Retroperitoneal fat weight1.13.56.50.21.81.2-2.01.61.92.0-2.22.22.6-2.11.5
Reaction time number correct0.81.22.8-1.51.7-0.8-1.31.61.50.4-0.30.30.2-1.2-0.4
Reaction time mean minus median0.30.41.3-1.10.1-1.00.10.30.3-0.60.5-0.5-0.3-0.1-1.1
Reaction time mean minus median AUC0.70.92.8-1.71.1-1.1-0.71.21.2-0.20.0-0.00.0-0.9-0.9
Reaction time num false alarms1.01.43.31.6-1.80.31.4-1.1-1.4-0.70.8-0.8-0.71.4-0.8
Reaction time num false alarms AUC0.91.33.11.4-1.80.21.4-1.3-1.5-0.90.8-0.8-0.61.4-0.7
Reaction time trials correct on left0.81.22.8-1.51.7-0.8-1.31.61.50.4-0.30.30.2-1.2-0.4
Reaction time trials on left0.91.22.9-1.61.7-0.8-1.31.61.50.4-0.30.30.2-1.2-0.5
Reaction time mean0.20.31.01.0-0.70.60.4-0.7-0.50.1-0.20.20.70.30.4
Reaction time mean AUC0.10.10.30.6-0.50.20.4-0.5-0.4-0.10.0-0.00.40.30.0
Median of all reaction times0.60.83.11.7-0.81.20.4-1.0-0.80.5-0.50.51.10.31.0
Reaction time omissions0.30.40.9-0.5-0.5-0.70.7-0.6-0.4-0.90.7-0.7-0.40.5-0.6
Reaction time false alarm rate1.62.25.62.0-2.40.71.8-1.9-2.0-0.80.7-0.7-0.61.7-0.3
Reaction time premature initiation rate0.60.81.50.10.80.7-1.00.60.71.0-1.21.20.8-1.01.1
Reaction time premature initiations1.11.53.0-0.91.7-0.0-1.61.61.61.0-1.11.10.6-1.60.4
Std. dev. reaction times0.20.30.7-0.5-0.6-0.50.6-0.4-0.4-0.80.6-0.6-0.40.5-0.8
Reaction time trials completed0.91.22.9-1.61.7-0.8-1.31.61.50.4-0.30.30.2-1.2-0.5
Reaction time trials AUC0.91.33.0-1.51.7-0.7-1.41.61.60.5-0.40.40.3-1.3-0.3
Run reversals in cocaine runway, females0.50.40.80.6-0.80.30.7-0.9-0.9-0.40.6-0.6-0.70.80.1
Run reversals in cocaine runway, males0.90.82.4-1.01.4-0.5-1.11.61.40.4-0.20.2-0.2-1.0-0.5
Latency to leave start box in cocaine runway0.91.03.20.00.70.7-0.90.50.61.1-1.31.31.8-0.91.1
Latency to leave start box in cocaine runway, F0.20.20.70.3-0.70.10.5-0.7-0.6-0.1-0.20.20.80.40.4
Latency to leave start box in cocaine runway, M1.61.52.7-0.71.70.2-1.51.41.51.0-1.11.11.4-1.60.5
Std. dev. time between licks in bursts0.10.10.5-0.6-0.1-0.40.4-0.00.1-0.30.3-0.3-0.7-0.0-0.5
Total sessions with >9 infusions1.01.13.1-0.7-1.3-0.61.4-1.8-1.4-1.00.5-0.5-0.81.20.3
Short access day 1 total inactive lever presses1.11.36.8-1.1-0.1-1.00.30.2-0.0-0.61.3-1.3-2.60.4-1.4
Short access day 10 total inactive lever presses0.20.20.50.20.50.1-0.40.70.60.30.3-0.3-0.4-0.4-0.5
Short access day 1 total infusions0.70.71.0-0.9-0.8-0.70.9-1.0-0.8-0.90.9-0.9-0.80.9-0.5
Short access day 10 total infusions0.70.72.60.0-1.2-0.01.0-1.6-1.3-0.6-0.20.2-0.31.00.7
Short access total infusions1.11.33.9-0.8-1.4-0.61.5-2.0-1.6-1.00.5-0.5-0.81.30.4
Short access day 1 locomotion0.80.91.8-0.4-1.2-0.51.1-1.4-1.3-1.10.6-0.6-0.91.3-0.2
Short access day 10 total locomotion1.21.34.9-1.9-0.5-2.21.0-0.7-0.5-1.60.8-0.8-0.10.6-1.3
Short access total locomotion0.70.71.9-0.9-0.8-1.00.9-1.4-1.0-1.00.2-0.2-0.40.90.3
One hour access (0.3 mA shock)0.80.95.0-2.20.8-1.4-0.40.70.8-0.40.6-0.6-0.2-0.5-1.0
Compulsive drug intake0.30.31.1-1.00.8-0.8-0.60.10.4-0.1-0.10.10.2-0.10.5
One hour access (shock baseline)0.60.73.3-1.80.6-1.0-0.20.80.8-0.30.3-0.3-0.3-0.6-1.4
Social response proportion0.50.50.90.8-1.01.00.7-0.8-0.9-0.00.6-0.6-0.70.60.2
Social responses0.30.41.10.3-0.60.40.3-0.8-1.1-0.10.5-0.5-0.60.80.8
Social time0.30.41.6-1.2-0.4-0.60.6-0.6-0.4-0.70.6-0.6-0.40.4-0.4
Soleus weight0.41.14.1-2.00.2-1.90.4-0.4-0.0-1.11.0-1.0-0.90.3-0.5
Bone: stiffness0.60.92.3-1.3-0.5-1.20.7-0.2-0.3-1.11.0-1.0-0.90.5-1.5
Tibialis anterior weight4.515.520.71.64.13.2-4.43.63.94.5-4.54.54.3-4.33.4
Time to tail flick, vehicle, before self-admin1.31.32.71.4-1.51.40.7-1.0-1.40.20.7-0.7-1.61.20.8
Time to tail flick, vehicle, after self-admin4.34.67.10.82.21.4-2.41.81.92.5-2.72.71.8-2.12.6
Time to tail flick, test, before self-admin0.70.71.80.8-1.10.41.0-1.3-1.2-0.30.5-0.5-0.51.00.7
Time to tail flick, test, after self-admin0.70.71.40.1-0.8-0.10.7-1.2-1.2-0.60.9-0.9-0.81.10.8
Delta time to tail flick, vehicle, before/after SA3.23.26.0-0.82.4-0.3-2.01.82.21.3-2.02.02.0-2.10.8
Delta time to tail flick, test, before/after SA0.10.10.3-0.40.1-0.2-0.20.2-0.0-0.20.4-0.4-0.50.1-0.1
Tibia length0.10.10.30.5-0.20.00.2-0.4-0.5-0.00.5-0.5-0.30.60.3
Ambulatory time before self-admin0.40.41.2-0.20.8-0.1-0.71.10.90.5-0.10.1-0.3-0.8-0.3
Ambulatory time after self-admin0.80.91.80.1-1.0-0.51.1-1.0-0.9-0.91.3-1.3-0.80.9-0.7
Bone: tissue strength0.20.20.50.7-0.70.60.4-0.6-0.7-0.10.1-0.1-0.10.50.3
Total heroin consumption8.610.129.3-4.3-0.1-5.41.7-0.5-0.2-3.63.8-3.8-3.11.4-4.2
Bone: trabecular number0.00.10.30.10.10.2-0.1-0.10.20.2-0.30.30.6-0.30.2
Bone: trabecular spacing0.81.01.80.4-1.2-0.21.2-1.3-1.3-0.81.0-1.0-0.91.3-0.1
Bone: trabecular thickness2.22.64.31.11.41.5-1.61.51.61.9-1.91.92.1-1.80.9
Bone: trabecular tissue density0.10.20.70.8-0.30.70.1-0.2-0.40.2-0.20.20.10.20.5
Water consumed over 24 hours0.00.00.20.3-0.00.3-0.10.2-0.10.10.1-0.1-0.50.20.0
Number of responses in last shaping day0.30.30.60.1-0.60.60.1-0.8-0.80.00.1-0.1-0.70.60.8