Ern1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	PL	gene expression	Ern1	0.04	0.02	2.5e-05	0.04	0.04	0.03	0.04	2.1e-05	1.0e-05	1.5e-04	4.5e-05
2	RMTg	mRNA stability	Ern1	0.14	0.09	1.8e-03	0.09	0.07	0.05	0.09	2.6e-03	4.9e-03	2.2e-02	2.8e-03
3	Liver	mRNA stability	Ern1	0.04	0.03	2.1e-04	0.03	0.03	0.02	0.03	3.2e-04	2.5e-04	2.9e-03	6.2e-04
4	Liver	gene expression	Ern1	0.13	0.06	2.1e-10	0.06	0.09	0.09	0.1	3.9e-07	6.1e-10	7.8e-10	9.8e-11
5	Liver	alternative TSS	XM_006247634.4	0.05	0.03	4.6e-03	0.01	0.01	0.02	0	5.7e-02	4.1e-02	4.0e-03	1.1e-01
6	Liver	alternative TSS	XM_017597474.2	0.05	0.03	5.3e-03	0	0.01	0.01	0	9.1e-02	3.3e-02	2.6e-02	1.4e-01
7	Liver	alternative TSS	XM_006247634.4	0.06	0.03	1.3e-03	0.03	0.03	0.03	0.02	3.0e-04	4.6e-04	5.1e-04	1.8e-03
8	Liver	alternative TSS	XM_039086647.1	0.05	0.03	2.3e-03	0.02	0.03	0.02	0.01	1.7e-03	5.2e-04	4.3e-03	8.7e-03
9	Liver	alternative TSS	XM_017597474.2	0.05	0.03	2.0e-03	0.02	0.03	0.03	0.02	2.8e-03	3.1e-04	7.4e-04	2.7e-03
10	Adipose	mRNA stability	Ern1	0.13	0.05	5.8e-08	0.08	0.07	0.07	0.08	2.1e-09	5.8e-08	1.0e-08	2.8e-09

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	1.6	2.7	8.9	1.2	-0.7	-0.6	0.2	-1.6	-2.1	-3.0	-1.8	2.1	-1.2
Area under the delay curve	0.7	0.7	1.6	0.2	0.2	0.3	0.6	-0.8	-1.1	-0.8	-1.3	1.3	-1.0
BMI with tail	0.7	2.2	9.5	0.8	0.2	0.5	-0.4	3.0	3.1	-0.1	0.7	-0.9	1.1
BMI without tail	1.9	3.9	12.2	2.3	-1.3	-0.7	-1.6	3.5	3.4	0.0	1.0	-1.2	1.5
Body weight	0.9	3.9	12.4	3.5	-2.3	-1.3	-1.4	2.7	2.4	-1.7	0.9	-0.9	0.2
Weight adjusted by age	0.5	0.6	2.1	-0.8	0.8	0.7	1.0	-0.4	-0.4	1.4	-0.2	0.2	-0.9
Bone surface	2.5	4.5	11.3	2.9	-2.4	-1.7	-0.6	-1.8	-2.5	-3.4	-1.3	1.7	-1.6
Bone volume	2.1	3.6	9.9	2.6	-2.0	-1.5	-0.5	-1.4	-2.1	-3.1	-1.4	1.7	-1.4
Breakpoint value in progressive ratio session	1.8	2.0	3.8	1.0	-1.5	-1.1	-1.3	1.3	1.3	1.6	2.0	-1.9	0.7
Number of licking bursts	0.2	0.2	1.0	-0.1	-0.1	0.3	0.7	-0.6	-0.6	-0.0	-0.0	0.1	-1.0
Context. condit. distance diff. score	0.5	0.6	1.5	-0.0	-0.0	0.3	-0.1	0.9	1.2	0.8	1.1	-1.2	0.2
Locomotion velocity, session 1	0.7	0.7	4.5	1.0	-0.7	-0.5	-0.4	-0.4	-0.5	-2.1	-0.5	0.6	-0.1
Locomotion distance, session 1	0.3	0.4	2.3	0.5	0.3	0.6	0.4	0.0	-0.0	-1.5	-0.7	0.7	-0.5
Locomotion velocity, session 2	0.9	1.0	3.1	0.7	-0.9	-0.7	-0.7	1.0	0.8	0.3	1.8	-1.6	0.6
Locomotion distance, session 2	0.3	0.5	1.2	0.3	-0.1	0.6	0.3	1.0	0.9	-0.4	1.1	-1.0	-0.3
Locomotion velocity, session 3	0.4	0.5	1.3	-0.5	0.6	1.1	0.9	0.6	0.5	-0.7	0.5	-0.3	-0.8
Locomotion distance, session 3	0.2	0.2	0.9	0.0	0.0	0.5	0.6	-0.2	-0.3	-0.8	0.2	0.0	-0.9
Stereotopy head waving bouts, day 3	0.7	0.8	1.7	-0.7	0.9	0.5	0.7	-1.0	-1.0	-0.8	-1.2	1.3	-0.5
Stereotopy head waving duration, day 3	0.3	0.4	0.7	-0.5	0.6	0.7	0.7	-0.4	-0.4	-0.2	-0.6	0.7	-0.8
Locomotion velocity, session 7	0.2	0.2	0.6	-0.7	0.7	0.5	0.2	-0.1	-0.0	-0.8	-0.3	0.3	0.2
Locomotion distance, session 7	0.2	0.2	1.2	0.1	0.1	0.1	-0.2	0.4	0.4	1.1	0.5	-0.6	0.3
Stereotopy head waving bouts, day 7	0.3	0.3	0.6	-0.7	0.6	0.8	0.8	0.0	-0.1	-0.7	0.2	-0.1	-0.5
Stereotopy head waving duration, day 7	0.8	0.9	2.8	-1.7	1.1	1.3	1.4	-0.3	-0.4	-0.6	0.3	-0.1	-1.0
Locomotion velocity, session 8	0.6	0.7	1.1	0.8	-1.1	-0.8	-0.7	0.7	0.7	-0.8	1.0	-1.0	-0.0
Locomotion distance, session 8	0.8	1.1	2.7	0.5	-0.5	0.2	-0.3	1.4	1.6	0.8	1.6	-1.6	0.1
Degree of sensitization distance	0.3	0.3	1.4	0.6	-0.3	-0.6	-0.7	0.2	0.3	1.2	-0.0	-0.3	0.6
Degree of sensitization stereotypy	0.8	0.8	1.6	-1.1	0.8	1.1	0.9	0.9	0.8	-0.4	1.3	-1.1	-0.2
Conditioned locomotion	1.1	1.3	4.5	0.9	-1.0	-1.1	-1.2	0.8	0.9	2.1	0.8	-1.0	1.0
Cocaine response after cond. corrected	2.3	2.6	6.8	-0.9	0.9	0.8	1.2	-2.6	-2.5	-0.5	-1.8	1.8	-1.4
Cocaine response after cond. not corrected	2.8	3.1	8.2	-1.3	0.9	1.1	1.5	-2.8	-2.9	-1.0	-1.4	1.6	-1.8
Cocaine response before conditioning	0.3	0.3	0.7	-0.4	0.1	0.5	0.6	0.2	-0.2	-0.8	0.8	-0.5	-0.8
Saline control response	4.8	6.3	10.2	1.7	-1.8	-1.9	-2.4	3.2	3.2	2.2	2.8	-3.0	2.4
Bone: connectivity density	1.4	2.3	6.5	1.5	-1.1	-0.9	-0.1	-1.5	-2.0	-2.5	-1.4	1.6	-1.1
Bone: cortical apparent density	1.9	2.5	7.3	-2.2	2.7	2.4	2.0	-0.1	0.3	-0.3	-1.2	1.2	-0.6
Bone: cortical area	0.7	1.0	4.3	1.8	-0.8	0.0	0.2	0.8	0.6	-2.1	-0.3	0.6	-0.6
Bone: cortical porosity	3.1	3.4	9.4	2.4	-3.1	-2.6	-2.1	0.8	0.2	-1.3	1.7	-1.3	0.9
Bone: cortical porosity	1.5	1.6	4.7	1.9	-2.2	-1.5	-1.0	0.7	0.2	-1.5	1.2	-0.8	-0.0
Bone: cortical thickness	3.0	5.0	11.8	-2.1	3.2	3.4	3.0	0.5	0.7	-2.5	-1.5	1.8	-1.2
Bone: cortical thickness	1.9	2.2	6.3	-1.8	2.4	2.5	1.8	0.5	0.7	-1.4	-0.3	0.5	-0.2
Bone: cortical tissue density	1.7	2.3	6.8	-2.2	2.6	2.3	1.9	-0.1	0.3	-0.2	-1.1	1.1	-0.5
Condit. Reinf. active minus inactive responses	2.3	2.6	4.2	1.9	-2.1	-1.7	-1.7	1.6	1.1	0.6	1.9	-1.8	0.9
Condit. Reinf. active-inactive response ratio	1.1	1.1	2.2	1.1	-1.5	-1.2	-1.2	0.8	0.4	0.3	1.4	-1.3	0.6
Condit. Reinf. active responses	2.5	3.0	5.7	2.3	-2.4	-2.0	-1.8	1.7	1.3	0.7	1.9	-1.8	0.7
Condit. Reinf. inactive responses	0.3	0.4	1.9	1.4	-1.1	-0.7	-0.4	0.3	0.2	-0.1	-0.0	0.0	-0.4
Incentive salience index mean	1.6	2.0	3.9	1.8	-2.0	-1.6	-1.4	1.3	0.9	-0.3	1.7	-1.5	0.7
Condit. Reinf. lever presses	0.6	0.8	1.6	0.5	-0.9	-0.8	-0.4	1.2	1.0	-0.8	1.3	-1.1	0.5
Condit. Reinf. active minus inactive responses	2.0	2.5	8.5	2.9	-2.8	-1.4	-1.0	0.5	-0.1	-1.2	1.3	-1.0	-1.2
Condit. Reinf. active-inactive response ratio	1.4	1.4	4.5	1.8	-2.1	-1.5	-1.0	-0.4	-0.8	-1.4	0.6	-0.4	-0.6
Condit. Reinf. active responses	2.8	3.9	11.8	3.4	-3.2	-2.0	-1.8	1.5	1.0	0.2	2.0	-1.8	-0.2
Condit. Reinf. inactive responses	2.9	3.5	6.9	2.2	-1.6	-1.1	-1.5	2.6	2.4	1.9	1.9	-2.0	0.9
Condit. Reinf. lever presses	2.0	2.7	4.7	1.8	-1.7	-1.0	-1.4	2.2	2.0	0.0	2.2	-2.0	0.8
Condit. Reinf. lever reinforcers received	2.2	3.0	9.9	3.1	-2.9	-1.9	-1.6	1.1	0.7	0.1	1.6	-1.4	-0.1
Conditioned reinforcement - actives	0.6	0.6	0.9	1.0	-0.9	-0.8	-0.8	0.9	0.8	-0.2	0.7	-0.7	0.4
Conditioned reinforcement - inactives	0.6	0.7	2.1	1.5	-0.9	-0.7	-0.7	0.7	0.7	-1.3	0.2	-0.2	0.4
Conditioned locomotion	1.1	1.3	3.8	2.0	-1.6	-1.5	-1.6	0.5	0.4	-1.1	0.2	-0.2	0.6
Patch foraging indifference point 0 sec	2.2	3.6	10.8	3.3	-2.5	-1.8	-2.0	2.1	1.9	0.3	1.2	-1.3	0.6
Patch foraging indifference point AUC	0.7	0.8	2.4	1.6	-1.0	-0.8	-0.8	1.0	1.0	0.4	0.7	-0.7	-0.1
Delay disc. indifference point, 0s delay	0.8	0.9	1.3	-0.8	0.9	0.8	1.1	-1.0	-1.2	0.6	-1.1	1.0	-1.1
Delay disc. indifference point, 16s delay	0.3	0.3	0.8	0.6	-0.1	-0.1	0.2	-0.4	-0.8	0.1	-0.9	0.9	-0.6
Delay disc. indifference point, 2s delay	2.6	2.9	5.8	0.7	-0.1	0.3	1.1	-1.9	-2.4	-1.8	-2.1	2.1	-2.4
Delay disc. indifference point, 24s delay	0.6	0.6	2.8	1.7	-0.9	-0.6	-0.6	0.7	0.5	-0.6	-0.3	0.3	-0.3
Delay disc. indifference point, 4s delay	1.3	1.4	2.7	-1.0	1.1	1.0	1.4	-1.2	-1.6	-0.7	-1.1	1.2	-1.2
Delay disc. indifference point, 8s delay	1.2	1.2	2.6	-0.3	0.8	0.7	0.9	-1.2	-1.4	-0.9	-1.6	1.6	-1.0
Indifference point function ln k	0.2	0.3	0.8	-0.6	0.5	0.9	0.8	-0.1	-0.2	-0.5	-0.3	0.4	-0.4
Indifference point function log k	0.2	0.3	0.8	-0.6	0.5	0.9	0.8	-0.1	-0.2	-0.5	-0.3	0.4	-0.4
Patch foraging total patch changes 0 sec	2.0	3.3	11.1	3.3	-2.6	-1.8	-2.0	1.7	1.5	0.3	1.0	-1.1	0.5
Patch foraging total patch changes 12 sec	2.9	3.8	10.5	3.2	-2.7	-2.3	-2.1	1.5	1.4	1.1	1.5	-1.6	0.4
Patch foraging total patch changes 18 sec	2.4	3.1	5.8	2.4	-2.0	-1.5	-1.8	1.9	1.8	1.3	1.8	-1.8	1.0
Patch foraging total patch changes 24 sec	1.3	1.6	7.5	2.7	-1.9	-1.2	-1.0	1.2	0.7	-0.4	0.5	-0.4	-0.4
Patch foraging total patch changes 6 sec	1.1	1.6	5.9	2.4	-1.8	-1.2	-1.2	1.2	1.1	0.0	0.8	-0.7	0.3
Patch foraging time to switch 0 sec	0.2	0.3	1.4	-0.9	0.2	-0.3	-0.3	-0.2	-0.2	0.3	0.1	-0.1	1.2
Patch foraging water rate 0 sec	0.6	0.9	3.8	1.9	-1.0	-0.8	-1.1	0.8	0.7	-1.0	-0.1	0.0	0.1
Patch foraging water rate 12 sec	1.6	2.4	4.5	-1.2	1.7	2.1	2.0	-0.8	-1.0	-1.9	-1.3	1.5	-1.4
Patch foraging water rate 18 sec	1.2	1.7	5.6	-0.2	0.4	1.2	1.4	-0.9	-1.1	-2.4	-0.8	1.1	-1.8
Patch foraging water rate 24 sec	0.5	0.7	1.9	-0.2	0.2	0.8	0.9	-0.8	-0.9	-1.4	-0.5	0.6	-1.4
Patch foraging water rate 6 sec	0.9	1.3	2.9	-0.2	0.6	0.9	0.9	-1.0	-1.2	-1.7	-1.4	1.5	-1.1
Seeking ratio, delayed vs. immediate footshock	0.9	1.0	2.8	0.3	-0.3	-0.5	-0.9	1.7	1.7	0.7	0.8	-0.9	1.2
Distance traveled before self-admin	1.2	1.3	3.0	-0.9	0.3	0.9	1.3	-1.6	-1.7	0.1	-0.4	0.6	-1.7
Distance traveled after self-admin	0.5	0.5	1.3	-0.3	-0.2	0.5	0.6	-0.4	-0.3	1.1	1.1	-0.9	-1.0
Extensor digitorum longus weight	0.7	2.7	8.4	-1.8	1.6	-0.0	-0.9	0.9	1.8	2.9	-0.6	-0.0	2.7
Bone: elastic displacement	1.6	1.8	4.9	-1.5	1.6	1.7	1.6	-0.4	-0.4	-2.2	-0.6	0.9	-1.1
Bone: elastic work	0.9	1.2	9.2	-0.0	0.4	0.5	0.5	0.1	0.0	-3.0	-0.9	1.2	-0.3
Bone: endosteal estimation	5.8	12.5	36.0	5.9	-6.0	-5.1	-4.4	0.9	0.1	-0.0	2.1	-1.9	1.2
Bone: endosteal perimeter	5.5	11.5	38.1	6.2	-6.0	-4.8	-3.7	0.5	-0.3	-0.6	1.5	-1.3	0.2
Epididymis fat weight	0.5	1.2	2.5	1.6	-0.9	-1.4	-1.4	0.6	0.4	-0.5	-1.1	0.8	1.3
Delta time in closed arm before/after self-admin	0.7	0.7	2.6	-0.2	0.1	0.2	0.5	-1.3	-1.2	-1.6	-0.5	0.7	-0.7
Delta time in open arm before/after self-admin	0.7	0.7	5.0	-0.4	0.3	-0.0	-0.3	0.7	0.9	2.2	0.2	-0.4	0.4
Diff in mean of infusions in LGA sessions	0.6	0.7	1.6	-0.9	0.9	0.7	0.2	1.0	1.3	0.6	0.7	-0.7	0.8
Delay discount exponential model param	0.7	0.7	1.5	-0.5	0.0	-0.0	-0.4	0.8	1.1	1.0	1.2	-1.2	1.0
Extinction: sum of active levers before priming	1.1	1.1	4.0	0.7	-0.9	-0.7	-0.8	1.1	1.2	2.0	1.0	-1.1	0.3
Active lever presses in extinction session 6	1.8	1.7	2.8	1.5	-1.6	-1.7	-1.6	1.0	1.0	0.8	1.2	-1.2	1.3
Bone: final force	0.9	1.5	5.8	1.1	-0.3	0.6	1.0	-0.6	-0.9	-2.4	-1.0	1.3	-1.7
Bone: final moment	1.0	1.6	6.8	1.1	-0.3	0.5	1.0	-0.6	-0.9	-2.6	-1.0	1.4	-1.6
Food consumed during 24 hour testing period	2.2	2.6	4.8	2.2	-2.0	-1.8	-2.0	1.7	1.9	-0.3	0.9	-1.0	1.2
Glucose	0.4	0.7	1.7	-1.3	1.0	1.2	1.2	-0.5	-0.2	0.7	-0.1	0.1	-0.6
Heart weight	0.1	0.2	0.5	-0.0	0.1	0.6	0.5	0.6	0.2	0.2	-0.0	-0.0	-0.7
Delay discount hyperbolic model param	0.9	0.9	1.9	-0.3	-0.1	-0.2	-0.7	0.9	1.3	1.0	1.4	-1.4	1.2
Intermittent access intake day 1-15 change	0.7	0.7	2.4	0.2	-0.7	-1.2	-0.9	0.1	0.3	0.9	0.4	-0.5	1.6
Intermittent access intake escalation	0.4	0.4	2.1	-0.1	-0.3	-0.9	-0.6	0.1	0.4	0.5	0.3	-0.4	1.5
Intermittent access intake escalation 2	0.7	0.7	2.4	0.5	-0.9	-1.4	-1.1	-0.2	0.1	0.2	-0.0	-0.1	1.6
Intermitt. access day 1 inactive lever presses	2.2	2.4	6.6	2.6	-2.2	-1.5	-1.4	1.4	0.8	-0.4	1.7	-1.5	-0.0
Intermitt. access day 15 inactive lever presses	1.9	2.0	4.8	1.6	-1.5	-2.1	-2.2	0.9	0.7	0.5	0.7	-0.7	2.1
Intermitt. access escalation Index	2.7	2.4	5.0	-1.9	1.4	1.9	2.2	-1.4	-1.4	0.3	-0.3	0.4	-2.2
Intermittent access day 1 total infusions	0.4	0.5	1.6	1.2	-0.7	-0.1	-0.3	0.5	0.4	-1.3	0.1	-0.0	-0.9
Intermittent access day 15 total infusions	0.3	0.4	0.7	0.8	-0.7	-0.7	-0.7	0.6	0.7	-0.5	0.3	-0.4	0.3
Intermittent access terminal intake (last 3 days)	1.1	1.2	3.2	1.8	-1.6	-1.6	-1.4	0.5	0.5	-0.5	0.3	-0.4	0.5
Intermittent access total infusions	1.3	1.5	4.4	2.1	-1.7	-1.2	-1.2	1.0	1.0	-1.2	0.7	-0.7	0.1
Intermittent access day 1 locomotion	1.8	1.9	5.8	2.3	-1.8	-1.2	-1.4	0.9	0.7	-2.4	0.3	-0.2	0.1
Intermittent access day 15 total locomotion	2.8	3.0	7.3	2.7	-2.3	-2.0	-2.0	1.3	1.2	-2.2	0.8	-0.7	0.7
Intermittent access total locomotion	4.2	4.8	12.1	3.5	-2.8	-2.3	-2.5	1.9	1.7	-2.7	0.9	-0.9	1.1
Intermittent access standard deviation	1.4	1.5	2.8	1.3	-1.2	-1.4	-1.6	1.3	1.3	-1.0	0.5	-0.6	1.7
Left kidney weight	0.7	2.1	6.7	-0.8	1.7	2.6	2.0	0.5	0.4	-1.6	0.0	0.2	-1.8
Right kidney weight	0.7	2.0	6.6	-0.5	1.2	2.0	1.9	-0.0	-0.2	-2.6	-0.4	0.7	-1.9
Cocaine induced anxiety	0.6	0.7	1.5	-0.5	0.7	0.6	0.6	-0.9	-1.0	-1.2	-1.1	1.1	0.0
Post-drug Anxiety	1.5	1.7	3.5	-0.9	0.9	0.6	0.8	-1.8	-1.8	-1.1	-1.8	1.9	-0.2
Baseline Anxiety	0.8	0.9	1.2	-1.1	1.1	0.9	0.9	-0.9	-0.9	-0.3	-1.1	1.1	-0.6
Tail length	0.8	2.4	8.0	2.8	-2.5	-2.0	-1.7	0.9	0.6	-1.1	0.2	-0.2	0.3
Length with tail	0.7	2.6	7.9	2.8	-2.4	-1.7	-0.7	-0.4	-0.8	-2.5	-0.4	0.6	-1.2
Length without tail	0.8	1.7	4.6	0.6	-0.5	-0.4	0.5	-1.8	-1.9	-2.2	-1.0	1.2	-1.4
Times rat made contact with spout	0.3	0.4	1.3	0.9	-0.9	-0.8	-0.6	0.1	-0.0	-1.1	0.1	-0.1	0.1
Lifetime Intake	1.8	2.1	5.6	2.4	-1.9	-1.3	-1.4	1.6	1.5	-0.8	1.1	-1.1	0.2
Liver weight, left	0.5	0.8	2.2	1.1	-1.2	-0.4	0.2	-0.8	-0.9	-1.2	-0.2	0.4	-1.5
Liver weight, right	2.8	4.6	7.3	-0.6	1.6	2.0	2.4	-2.2	-2.1	-2.2	-2.6	2.7	-2.3
Locomotor activity	2.8	4.5	12.0	1.3	-1.3	-0.0	-1.0	3.5	3.4	-0.5	3.0	-2.8	0.5
Locomotor testing distance	5.1	8.4	20.2	2.0	-2.2	-1.2	-2.3	4.5	4.1	0.6	3.8	-3.8	1.7
Locomotor testing rearing	6.8	10.4	20.3	1.6	-2.3	-1.9	-3.0	4.5	4.2	1.3	4.2	-4.2	3.1
Locomotion in novel chamber	1.0	1.2	3.5	-0.3	0.4	0.7	1.1	-1.1	-1.5	-1.9	-0.5	0.7	-1.4
Locomotion in novel chamber post-restriction	1.4	1.7	3.4	1.5	-1.3	-0.7	0.1	-1.5	-1.8	-1.1	-1.3	1.3	-1.6
Fecal boli incidents, locomotor time 1	0.4	0.5	3.4	-0.1	-0.1	-0.3	-0.0	-0.7	-0.7	1.9	-0.2	0.1	-0.4
Change in fecal boli incidents, locomotor task	0.4	0.3	1.1	-0.3	0.8	0.5	0.5	-0.1	0.0	-0.3	-1.0	0.9	0.3
Time >=10cm from walls, locomotor time 1	1.6	1.7	3.9	-1.7	1.4	2.0	2.0	-0.9	-0.8	0.2	-0.0	0.2	-1.5
Bouts of movement, locomotor time 1	0.4	0.4	1.9	-0.6	0.7	0.1	-0.2	0.4	0.4	-0.2	-0.6	0.5	1.4
Total resting periods, locomotor time 1	0.5	0.5	1.5	-0.7	0.9	0.1	-0.1	-0.1	-0.0	-0.4	-1.1	1.0	1.2
Rest time, locomotor task time 1	0.6	0.7	1.7	-0.7	0.4	-0.1	0.2	-1.1	-1.3	1.1	-1.1	1.0	0.0
Distance moved, locomotor task time 1	0.7	0.8	4.8	1.0	-0.5	-0.5	-0.5	0.6	0.7	-2.2	0.2	-0.2	0.5
Vertical activity count, locomotor time 1	0.5	0.5	4.4	0.6	-0.2	-0.0	0.0	-0.5	-0.3	-2.1	-0.1	0.2	-0.2
Time >=10cm from walls, locomotor time 2	0.2	0.2	0.5	-0.7	0.1	0.1	0.2	-0.5	-0.5	-0.7	0.0	0.1	0.5
Bouts of movement, locomotor time 2	0.6	0.7	3.1	-0.4	0.5	-0.1	-0.4	0.9	0.8	1.8	0.1	-0.2	1.3
Total resting periods, locomotor time 2	0.6	0.7	3.4	-0.7	0.8	0.2	-0.1	0.7	0.6	1.8	0.0	-0.2	1.0
Rest time, locomotor task time 2	3.3	3.8	5.7	-2.4	2.0	1.6	1.9	-2.1	-2.2	2.3	-1.7	1.6	-1.5
Distance moved, locomotor task time 2	1.5	1.8	6.4	0.8	-0.7	-0.9	-1.2	1.2	1.3	-2.5	0.9	-0.8	1.8
Vertical activity count, locomotor time 2	3.4	3.7	6.0	1.9	-2.0	-2.0	-2.4	1.8	2.0	-1.2	1.7	-1.7	2.2
Light reinforcement 1	0.6	1.1	3.6	1.0	-0.6	-0.3	-0.6	1.9	1.7	1.2	0.6	-0.7	0.3
Light reinforcement 2	0.2	0.3	0.9	1.0	-0.6	-0.5	-0.6	0.4	0.2	0.5	-0.6	0.6	0.0
Bone: marrow area	5.6	12.1	34.9	5.8	-5.9	-5.0	-4.3	0.8	0.0	-0.1	2.0	-1.9	1.2
Bone: maximum diameter	1.3	2.4	10.3	3.2	-2.7	-1.6	-0.8	-0.3	-0.8	-1.1	-0.1	0.4	-1.1
Bone: maximum force	0.8	1.3	4.6	2.0	-0.8	0.1	0.4	0.1	-0.3	-2.1	-0.9	1.1	-1.3
Bone: maximum moment	0.8	1.4	5.6	2.0	-0.9	0.0	0.4	-0.0	-0.3	-2.4	-1.0	1.2	-1.2
Mean time between licks in bursts	0.2	0.2	0.7	0.4	-0.1	0.0	0.2	-0.6	-0.5	-0.1	-0.8	0.8	-0.6
Mean num. licks in bursts	0.4	0.5	1.3	0.7	-0.4	-0.8	-1.1	0.7	0.6	-0.4	-0.1	-0.1	1.1
Cd content in liver	1.0	1.1	4.0	-2.0	1.7	1.0	0.9	-1.0	-0.7	0.7	-0.4	0.3	0.0
Co content in liver	0.5	0.6	1.6	-0.7	-0.0	-0.3	-0.5	0.6	0.8	0.8	1.2	-1.3	0.8
Cu content in liver	0.3	0.4	1.1	0.4	-0.6	-1.1	-0.9	-0.1	-0.1	0.6	-0.2	0.1	0.8
Fe content in liver	0.5	0.6	1.4	-0.2	0.2	0.4	0.3	0.9	0.9	1.2	1.1	-1.1	0.2
K content in liver	0.6	0.6	2.3	0.9	-1.1	-0.5	0.4	-0.7	-0.9	-0.2	0.1	0.1	-1.5
Mg content in liver	0.3	0.3	0.7	0.1	-0.5	-0.5	0.1	-0.8	-0.7	0.6	-0.3	0.3	-0.6
Mn content in liver	1.0	1.1	4.4	0.1	0.2	0.8	1.3	-1.0	-1.2	-0.9	-0.6	0.8	-2.1
Na content in liver	0.8	0.9	2.5	0.8	-1.2	-0.3	0.0	0.7	0.5	0.7	1.6	-1.3	-1.1
Rb content in liver	1.4	1.7	3.6	-1.9	1.7	1.9	1.9	-0.9	-0.7	0.6	-0.2	0.3	-1.4
Se content in liver	0.8	0.9	2.1	-1.1	1.0	1.3	1.4	-0.5	-0.4	0.9	-0.1	0.2	-1.5
Sr content in liver	0.5	0.4	2.1	0.5	-0.2	0.1	0.1	-0.5	-0.5	-1.5	-0.5	0.7	-0.7
Zn content in liver	1.8	2.0	7.4	0.2	-0.0	0.7	1.3	-1.7	-1.9	-1.0	-1.0	1.3	-2.7
Bone: minimum diameter	4.3	8.0	28.5	5.3	-4.7	-3.8	-3.0	1.1	0.4	-1.6	0.9	-0.7	0.4
Time in familiar zone, hab. session 1	0.9	0.9	2.3	0.9	-1.0	-1.2	-1.2	0.3	0.4	1.5	0.5	-0.7	0.8
Time in novel zone, hab. session 1	0.8	0.8	1.8	-1.1	1.2	1.3	1.1	-0.3	-0.2	-1.0	-0.5	0.7	-0.3
Total zone transitions, hab. session 1	0.6	0.8	2.7	0.7	-0.2	0.3	-0.2	1.5	1.7	-1.3	0.7	-0.7	0.2
Total locomotion distance, hab. session 1	0.9	1.3	8.6	1.2	-0.4	0.1	-0.3	1.0	1.1	-2.9	0.1	0.0	0.2
Locomotion velocity, hab. session 1	0.9	1.3	8.3	1.4	-0.7	-0.2	-0.4	0.9	0.9	-2.9	0.1	0.0	0.1
Time in familiar zone, hab. session 2	2.2	2.3	3.9	1.4	-1.7	-1.4	-1.4	1.4	1.4	1.4	1.9	-2.0	0.8
Time in novel zone, hab. session 2	3.5	3.5	6.8	-1.4	1.8	1.5	1.6	-2.0	-2.0	-1.7	-2.6	2.6	-1.0
Total zone transitions, hab. session 2	0.8	1.1	3.8	0.5	-0.4	0.1	-0.3	1.8	1.9	-0.4	1.2	-1.2	0.4
Total locomotion distance, hab. session 2	0.6	0.8	2.4	1.1	-0.5	-0.2	-0.6	1.4	1.6	-0.9	0.3	-0.3	0.6
Locomotion velocity, hab. session 2	0.4	0.5	1.5	1.0	-0.3	-0.1	-0.4	1.1	1.2	-1.1	0.0	-0.1	0.3
Novel to familiar place preference ratio	0.2	0.2	0.4	0.6	-0.3	-0.2	0.1	-0.3	-0.3	-0.7	-0.5	0.6	-0.3
Novelty place preference	0.1	0.1	0.3	0.4	-0.1	-0.0	0.2	-0.2	-0.2	-0.6	-0.3	0.4	-0.2
Time in novel zone, NPP test	0.1	0.1	0.4	0.3	-0.0	0.1	0.4	-0.2	-0.1	-0.6	-0.2	0.3	-0.3
Total zone transitions, NPP test	0.6	0.8	2.3	0.5	0.1	0.9	0.5	1.4	1.4	-1.5	0.4	-0.3	-0.6
Total locomotion distance, NPP test	0.6	0.8	5.4	1.1	-0.3	0.0	-0.3	0.7	0.7	-2.3	-0.2	0.2	0.2
Locomotion velocity, NPP test	0.4	0.6	2.8	1.1	-0.2	0.1	-0.3	1.0	1.0	-1.7	-0.3	0.2	0.2
Intraocular pressure	0.9	1.2	2.4	1.1	-0.6	-0.8	-1.2	1.4	1.6	1.3	0.4	-0.6	1.5
Delta distance traveled before/after self-admin	0.9	1.0	2.5	-0.2	0.1	0.3	-0.2	1.4	1.6	0.9	1.5	-1.4	0.6
Delta ambulatory time before/after self-admin	0.3	0.3	0.8	0.3	-0.2	-0.1	-0.3	0.7	0.9	0.5	0.9	-0.9	0.4
Parametrial fat weight	1.9	3.8	8.3	1.0	-0.8	-1.0	-0.2	-2.3	-2.5	-2.9	-2.7	2.8	-0.8
Pavlov. Cond. lever latency	1.4	1.8	3.5	-1.6	1.5	0.9	0.7	-1.7	-1.2	1.9	-1.5	1.2	-0.1
Pavlov. Cond. magazine entry latency	1.8	2.3	5.0	2.2	-2.2	-1.7	-1.3	1.6	1.0	-0.9	1.5	-1.3	0.4
Pavlov. Cond. change in total contacts	2.6	2.8	4.4	1.8	-2.0	-1.7	-1.6	2.1	1.7	-0.9	1.9	-1.7	0.8
Pavlov. Cond. index score	1.9	2.4	4.4	2.1	-2.1	-1.4	-1.1	1.9	1.3	-1.2	1.7	-1.5	0.1
Pavlov. Cond. latency score	1.9	2.4	4.0	1.9	-1.9	-1.2	-1.0	2.0	1.5	-1.2	1.9	-1.6	0.0
Pavlov. Cond. lever contacts	1.7	2.0	3.5	1.3	-1.6	-1.3	-1.1	1.9	1.5	-1.3	1.7	-1.5	0.7
Pavlov. Cond. magazine entry number	1.3	1.7	3.7	-1.9	1.9	1.5	1.2	-1.3	-0.8	0.8	-1.3	1.1	-0.2
Pavlov. Cond. intertrial magazine entries	1.3	1.5	2.7	1.7	-1.1	-0.7	-1.0	1.6	1.6	1.7	0.9	-1.1	0.1
Pavlov. Cond. lever-magazine prob. diff.	1.6	2.0	3.7	1.9	-1.9	-1.3	-0.9	1.7	1.2	-1.2	1.6	-1.3	0.0
Pavlov. Cond. response bias	1.5	1.8	3.9	1.9	-2.0	-1.5	-1.1	1.3	0.7	-1.5	1.3	-0.9	0.2
Pavlov. Cond. lever latency	0.3	0.5	1.3	-0.8	0.9	0.1	0.1	-0.7	-0.6	0.0	-1.1	1.0	0.4
Pavlov. Cond. magazine entry latency	1.3	1.5	3.7	-1.8	1.4	1.8	1.9	-0.9	-0.7	0.4	-0.0	0.1	-1.3
Pavlov. Cond. change in total contacts	0.7	0.9	2.6	0.9	-1.2	-0.5	-0.4	0.9	0.8	0.6	1.6	-1.5	-0.2
Pavlov. Cond. index score	0.2	0.3	1.0	-0.1	-0.2	0.5	0.6	0.2	0.2	0.3	1.0	-0.8	-0.6
Pavlov. Cond. latency score	0.2	0.3	1.0	-0.3	-0.1	0.6	0.7	0.1	0.1	0.2	1.0	-0.8	-0.7
Pavlov. Cond. lever contacts	0.3	0.4	1.0	0.7	-0.7	-0.1	-0.2	0.8	0.8	-0.1	1.0	-0.9	-0.1
Pavlov. Cond. magazine entry number	1.6	2.0	4.7	2.1	-1.8	-2.1	-2.2	1.0	0.7	-0.0	0.0	-0.2	1.3
Pavlov. Cond. intertrial magazine entries	6.0	7.8	20.4	4.5	-4.1	-4.3	-4.0	1.4	0.8	0.4	0.2	-0.4	1.8
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.3	0.6	-0.2	-0.0	0.6	0.8	-0.0	0.0	0.2	0.8	-0.6	-0.8
Pavlov. Cond. response bias	0.1	0.1	0.3	0.2	-0.1	0.4	0.4	0.1	0.2	-0.0	0.5	-0.4	-0.6
Time in closed arm before self-admin	0.7	0.8	1.5	-1.0	0.9	1.2	0.6	1.1	1.0	-0.8	0.8	-0.7	0.1
Time in closed arm after self-admin	0.8	0.9	3.2	-1.1	0.7	1.1	1.1	-0.5	-0.5	-1.8	0.1	0.1	-0.8
Time in open arm before self-admin	0.8	0.8	1.8	-1.0	0.7	0.6	0.8	-1.3	-1.3	-0.8	-0.8	0.9	-0.4
Time in open arm after self-admin	0.4	0.4	2.8	0.3	-0.2	-0.7	-0.6	-0.1	0.1	1.7	-0.3	0.1	0.6
Bone: periosteal estimation	2.9	6.1	23.0	4.8	-4.2	-3.1	-2.5	0.8	0.1	-1.5	0.9	-0.6	0.1
Bone: periosteal perimeter	1.5	2.6	9.4	3.1	-2.6	-1.4	-0.5	-0.3	-0.8	-2.1	0.1	0.3	-1.3
Bone: post-yield work	0.7	0.9	3.5	1.9	-1.7	-1.2	-0.8	0.2	-0.0	-0.7	0.3	-0.3	-0.0
Progressive ratio test 1 active lever presses	2.0	2.1	7.1	2.7	-2.0	-1.3	-1.2	1.2	0.9	-1.1	1.1	-1.0	-0.5
Progressive ratio test 1 breakpoint	2.9	3.0	9.3	3.0	-2.4	-1.7	-1.7	1.7	1.4	-0.5	1.5	-1.4	-0.1
Progressive ratio test 1 inactive lever presses	2.8	3.1	8.3	2.9	-2.4	-1.3	-1.4	1.9	1.6	0.1	1.9	-1.8	-0.5
Progressive ratio test 2 active lever presses	1.8	2.0	7.1	2.7	-2.2	-1.9	-1.5	0.3	0.0	-1.3	0.2	-0.2	-0.1
Progressive ratio test 2 breakpoint	2.2	2.4	8.0	2.8	-2.6	-2.2	-1.8	0.2	-0.0	-1.2	0.3	-0.2	0.1
Progressive ratio test 2 inactive lever presses	1.8	2.1	7.5	2.7	-2.1	-1.7	-1.6	1.0	0.8	-1.0	0.4	-0.4	0.2
Incentive Sensitization - Responses	1.3	1.3	3.8	1.9	-2.0	-1.7	-1.2	-0.5	-0.6	-0.6	-0.1	0.1	-0.1
Incentive Sensitization - Breakpoint	1.2	1.2	3.6	1.8	-1.9	-1.6	-1.1	-0.6	-0.7	-0.7	-0.2	0.2	-0.2
Sum of active levers in priming session hrs 5-6	1.7	1.7	6.6	-0.3	-0.2	0.0	-0.3	1.4	1.5	2.6	1.6	-1.7	0.3
Progressive ratio	1.4	1.6	4.0	-0.3	0.5	0.3	1.0	-2.0	-2.0	-0.5	-1.4	1.5	-1.4
Food seeking constrained by brief footshock	2.5	3.0	5.8	2.1	-2.3	-2.4	-2.2	1.1	1.1	0.4	1.7	-1.7	1.3
Seeking ratio, punishment vs. effort	2.8	3.4	4.9	1.5	-1.7	-1.6	-1.9	2.2	2.2	0.7	2.1	-2.2	1.8
Retroperitoneal fat weight	0.7	2.3	6.0	2.5	-1.7	-1.8	-1.9	1.0	1.0	-1.9	-0.1	-0.0	1.3
Reaction time number correct	1.7	2.5	4.0	-1.0	1.2	1.8	1.9	-1.7	-1.6	-1.1	-1.6	1.7	-2.0
Reaction time mean minus median	0.3	0.4	1.5	-0.8	0.8	-0.2	-0.1	-0.2	-0.3	0.5	-0.6	0.4	1.2
Reaction time mean minus median AUC	0.7	0.9	2.2	-1.3	1.5	1.1	1.2	-0.6	-0.7	0.2	-0.9	0.8	-0.3
Reaction time num false alarms	1.5	2.1	5.6	2.4	-2.2	-1.1	-0.9	1.4	1.0	-0.3	1.6	-1.4	-0.6
Reaction time num false alarms AUC	1.4	1.9	6.2	2.5	-2.3	-1.3	-0.9	1.1	0.6	-0.8	1.2	-1.0	-0.7
Reaction time trials correct on left	1.7	2.5	4.0	-1.0	1.2	1.8	1.9	-1.7	-1.6	-1.1	-1.6	1.7	-2.0
Reaction time trials on left	1.9	2.7	4.0	-1.0	1.2	1.8	1.9	-1.8	-1.7	-1.2	-1.7	1.8	-2.0
Reaction time mean	0.4	0.5	1.6	-1.3	1.2	0.6	0.6	-0.5	-0.7	0.8	-0.3	0.2	0.2
Reaction time mean AUC	0.4	0.6	2.1	-1.5	1.2	0.5	0.4	-0.1	-0.4	1.1	0.1	-0.1	0.6
Median of all reaction times	0.3	0.5	1.4	-1.2	1.1	0.7	0.6	-0.4	-0.6	0.8	-0.0	0.0	-0.0
Reaction time omissions	0.8	1.1	3.1	-0.2	0.6	-0.1	0.2	-1.3	-1.6	0.1	-1.8	1.7	0.4
Reaction time false alarm rate	2.3	3.2	6.4	2.5	-2.5	-2.0	-1.8	1.8	1.3	-0.1	2.0	-1.8	0.6
Reaction time premature initiation rate	0.8	1.1	1.8	1.3	-1.0	-0.9	-1.3	1.3	1.3	0.5	0.6	-0.6	0.9
Reaction time premature initiations	0.1	0.1	0.6	0.7	-0.4	-0.0	-0.2	0.3	0.3	-0.1	-0.3	0.3	-0.3
Std. dev. reaction times	0.4	0.6	1.0	-1.0	1.0	-0.0	0.1	-0.8	-1.0	0.4	-0.9	0.8	0.9
Reaction time trials completed	1.9	2.7	4.0	-1.0	1.2	1.8	1.9	-1.8	-1.7	-1.2	-1.7	1.8	-2.0
Reaction time trials AUC	1.8	2.6	3.8	-1.0	1.2	1.8	1.9	-1.7	-1.6	-1.2	-1.7	1.7	-1.9
Run reversals in cocaine runway, females	1.0	1.0	2.7	-0.9	1.0	-0.2	-0.6	-0.7	-0.5	-1.0	-1.4	1.2	1.6
Run reversals in cocaine runway, males	0.6	0.6	1.3	-0.4	0.5	0.4	0.7	-1.2	-1.1	-0.1	-0.8	0.8	-0.7
Latency to leave start box in cocaine runway	0.1	0.2	0.5	-0.7	0.5	0.6	0.5	0.1	-0.0	0.3	0.2	-0.2	-0.3
Latency to leave start box in cocaine runway, F	0.6	0.6	1.8	-0.9	1.0	1.3	1.3	0.1	-0.1	-0.2	0.4	-0.2	-0.8
Latency to leave start box in cocaine runway, M	0.2	0.2	0.5	-0.2	-0.3	-0.6	-0.7	-0.1	0.0	0.7	-0.1	-0.0	0.6
Std. dev. time between licks in bursts	0.2	0.2	0.5	0.1	-0.1	-0.3	-0.4	0.5	0.6	0.7	0.0	-0.1	0.7
Total sessions with >9 infusions	0.7	0.8	2.7	0.8	-0.2	0.5	0.1	1.6	1.4	-0.7	0.8	-0.7	-0.7
Short access day 1 total inactive lever presses	0.5	0.6	3.3	1.1	-0.7	-0.2	-0.3	0.7	0.4	-1.8	0.4	-0.2	-0.3
Short access day 10 total inactive lever presses	0.8	0.9	1.8	1.0	-0.9	-1.0	-1.0	1.0	0.9	1.3	0.5	-0.7	0.7
Short access day 1 total infusions	1.9	2.0	5.6	1.5	-1.1	-0.1	-0.5	2.4	2.2	0.2	1.8	-1.7	-0.5
Short access day 10 total infusions	3.5	3.9	9.8	3.1	-2.7	-2.0	-2.3	2.1	2.0	-0.2	1.4	-1.4	0.9
Short access total infusions	3.5	3.9	7.1	2.4	-2.2	-1.2	-1.7	2.7	2.5	0.2	2.3	-2.2	0.6
Short access day 1 locomotion	2.3	2.5	6.1	2.5	-1.8	-1.2	-1.6	2.2	2.0	-0.4	1.0	-1.0	0.6
Short access day 10 total locomotion	7.4	8.2	15.8	4.0	-3.6	-3.3	-3.4	3.1	2.8	-1.6	1.7	-1.8	2.4
Short access total locomotion	5.3	5.5	10.7	2.9	-2.4	-1.9	-2.4	3.3	3.0	-1.0	2.0	-1.9	1.5
One hour access (0.3 mA shock)	0.8	0.9	1.6	1.3	-1.3	-0.9	-1.0	0.9	0.7	0.6	1.1	-1.1	0.0
Compulsive drug intake	1.9	1.9	2.9	-1.3	1.2	1.6	1.7	-1.4	-1.7	-1.1	-0.9	1.1	-1.5
One hour access (shock baseline)	1.7	2.0	2.8	1.7	-1.5	-1.5	-1.6	1.5	1.7	0.5	1.3	-1.3	1.0
Social response proportion	0.1	0.1	0.3	-0.5	0.6	0.6	0.5	-0.1	-0.1	0.1	-0.2	0.1	-0.4
Social responses	0.6	0.8	1.9	0.4	-0.4	0.2	-0.0	1.4	1.3	0.1	1.4	-1.3	-0.0
Social time	0.2	0.3	0.9	-0.2	-0.3	-0.6	-0.4	-0.7	-0.9	0.6	-0.2	0.2	0.3
Soleus weight	0.1	0.4	1.0	0.6	-0.4	0.0	0.0	1.0	0.7	-0.4	0.8	-0.7	-0.6
Bone: stiffness	0.4	0.6	2.1	1.5	-0.8	0.3	0.6	0.3	0.1	-0.5	0.1	0.0	-1.4
Tibialis anterior weight	0.8	2.8	6.5	0.9	-0.9	-1.5	-2.1	2.2	2.5	1.1	0.8	-1.1	2.3
Time to tail flick, vehicle, before self-admin	3.8	3.9	11.5	-0.8	0.8	0.7	1.5	-2.9	-3.4	-1.1	-2.1	2.2	-2.0
Time to tail flick, vehicle, after self-admin	1.2	1.2	2.8	0.8	-0.7	-0.6	-0.1	-1.7	-1.7	0.4	-1.3	1.3	-1.3
Time to tail flick, test, before self-admin	0.5	0.5	1.4	-1.1	0.7	-0.1	0.1	-1.2	-0.9	0.3	-0.7	0.6	0.5
Time to tail flick, test, after self-admin	0.3	0.3	0.7	-0.4	0.3	0.4	0.6	-0.6	-0.8	-0.0	-0.7	0.7	-0.5
Delta time to tail flick, vehicle, before/after SA	1.5	1.5	3.4	1.7	-1.6	-1.7	-1.8	0.4	0.8	0.8	0.2	-0.4	1.0
Delta time to tail flick, test, before/after SA	0.2	0.2	1.3	0.2	-0.1	0.5	0.6	-0.1	-0.4	0.0	-0.2	0.2	-1.1
Tibia length	1.0	2.7	8.8	0.0	0.8	1.7	2.0	-0.8	-1.0	-3.0	-1.1	1.4	-2.5
Ambulatory time before self-admin	0.8	0.8	2.5	-0.6	0.1	0.7	1.1	-1.2	-1.3	-0.3	-0.2	0.4	-1.6
Ambulatory time after self-admin	0.2	0.3	0.9	0.1	-0.4	0.2	0.2	-0.2	-0.2	0.6	0.9	-0.7	-0.7
Bone: tissue strength	1.4	1.4	3.3	-1.0	1.4	1.8	1.8	-0.5	-0.6	-0.6	-0.6	0.7	-1.6
Total heroin consumption	0.3	0.4	1.1	0.6	-0.8	-0.3	-0.1	0.4	-0.1	0.3	1.1	-0.9	-0.6
Bone: trabecular number	1.4	2.2	5.9	1.7	-1.1	-0.7	0.0	-1.4	-1.9	-2.4	-1.3	1.6	-1.5
Bone: trabecular spacing	1.0	1.3	2.6	-0.7	0.1	0.0	-0.4	1.2	1.6	1.6	1.5	-1.6	1.0
Bone: trabecular thickness	2.0	2.4	5.7	1.5	-0.9	-1.1	-0.3	-1.4	-1.9	-2.4	-2.0	2.2	-0.5
Bone: trabecular tissue density	2.5	3.5	5.1	-1.0	2.1	2.3	2.3	-1.6	-1.5	-1.2	-2.2	2.3	-1.8
Water consumed over 24 hours	0.2	0.3	2.0	0.3	0.1	0.2	0.0	0.4	0.4	-1.4	-0.3	0.4	-0.1
Number of responses in last shaping day	0.4	0.4	0.9	1.0	-0.8	-0.6	-0.7	0.5	0.4	-0.6	0.6	-0.5	0.2