Hub : Genes

Enkur

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain intron excision ratio chr17_83703535_83714117 0.17 0.08 2.2e-16 0.1 0.16 0.16 0.16 1.2e-09 9.8e-15 6.3e-15 6.9e-15
2 Brain isoform ratio XM_039095565.1 0.07 0.04 5.3e-07 0.04 0.06 0.07 0.06 1.0e-04 1.0e-06 7.5e-07 1.1e-06
3 Brain isoform ratio NM_001106126.1 0.07 0.04 4.6e-07 0.04 0.07 0.07 0.07 9.7e-05 8.0e-07 5.8e-07 7.9e-07
4 NAcc intron excision ratio chr17_83703535_83705494 0.03 0.02 2.5e-04 0.02 0.03 0.03 0.02 4.1e-03 1.7e-04 5.0e-04 1.0e-03
5 PL isoform ratio NM_001106126.1 0.14 0.06 5.9e-13 0.13 0.12 0.13 0.12 8.9e-14 3.6e-13 7.4e-14 1.5e-13
6 PL isoform ratio XM_039095565.1 0.14 0.06 6.1e-13 0.13 0.12 0.13 0.13 6.5e-14 2.5e-13 4.3e-14 7.6e-14
7 OFC isoform ratio XM_039095565.1 0.31 0.18 1.6e-03 0.02 0.04 0.1 0.05 8.8e-02 3.4e-02 2.8e-03 2.3e-02
8 OFC isoform ratio NM_001106126.1 0.29 0.17 2.1e-03 0.01 0.03 0.09 0.04 1.4e-01 7.0e-02 3.5e-03 4.1e-02
9 NAcc intron excision ratio chr17_83703535_83714117 0.1 0.04 5.6e-13 0.1 0.12 0.11 0.12 6.9e-12 1.7e-13 7.5e-13 2.1e-13
10 Brain intron excision ratio chr17_83703535_83705494 0.04 0.02 1.9e-03 0.01 0.02 0.02 0.01 5.8e-02 4.9e-03 7.9e-03 1.7e-02
11 NAcc isoform ratio NM_001106126.1 0.05 0.03 5.5e-05 0.02 0.03 0.03 0.03 1.2e-03 6.6e-05 1.1e-04 1.2e-04
12 BLA intron excision ratio chr17_83705639_83714117 0.14 0.11 3.5e-03 0.01 0.01 0 0.01 7.3e-02 8.1e-02 2.2e-01 1.0e-01
13 NAcc isoform ratio XM_039095565.1 0.05 0.04 2.2e-05 0.03 0.04 0.04 0.04 3.3e-04 3.1e-05 3.1e-05 3.1e-05
14 BLA isoform ratio NM_001106126.1 0.07 0.05 6.5e-03 0.03 0.03 0.02 0.02 7.9e-03 1.0e-02 2.2e-02 2.5e-02
15 BLA isoform ratio XM_039095565.1 0.07 0.05 7.4e-03 0.03 0.03 0.02 0.02 1.0e-02 1.1e-02 3.3e-02 3.8e-02
16 PL intron excision ratio chr17_83703535_83705494 0.06 0.04 3.5e-05 0.03 0.04 0.03 0.03 1.1e-04 3.2e-05 2.8e-04 3.4e-04
17 PL intron excision ratio chr17_83705639_83714117 0.14 0.07 3.4e-10 0.09 0.09 0.09 0.1 1.7e-10 1.7e-10 1.4e-09 8.2e-11
18 NAcc gene expression Enkur 0.06 0.04 1.8e-05 0.05 0.05 0.05 0.04 2.2e-06 4.4e-06 1.7e-06 8.4e-06
19 NAcc intron excision ratio chr17_83705639_83714117 0.05 0.03 2.7e-04 0.04 0.03 0.03 0.04 1.2e-05 9.7e-05 9.5e-05 3.3e-05
20 Brain intron excision ratio chr17_83705639_83714117 0.08 0.05 1.5e-04 0.05 0.05 0.02 0.04 2.9e-05 1.8e-05 2.3e-03 8.0e-05
21 pVTA intron excision ratio chr17_83703535_83714117 0.08 0.05 4.5e-03 0.04 0.05 0.04 0.05 8.9e-03 2.4e-03 5.2e-03 2.4e-03
22 Brain mRNA stability Enkur 0.04 0.03 4.9e-03 0.03 0.02 0.05 0.02 9.5e-04 7.3e-03 1.4e-05 3.0e-03
23 Brain gene expression Enkur 0.15 0.08 5.3e-08 0.06 0.08 0.08 0.07 4.2e-06 4.8e-08 4.2e-08 8.1e-07
24 PL gene expression Enkur 0.24 0.1 1.1e-16 0.14 0.14 0.16 0.14 2.6e-15 1.9e-15 1.6e-17 2.2e-15
25 BLA gene expression Enkur 0.1 0.06 1.0e-03 0.06 0.06 0.07 0.07 4.1e-04 2.2e-04 1.1e-04 2.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.11.92.9-1.6-1.71.7-1.71.5-1.5-1.41.51.4-1.4-1.41.6-1.41.2-1.2-1.3-1.21.11.1-1.41.41.71.20.80.5
Area under the delay curve0.30.31.30.10.1-0.10.5-0.50.50.00.0-0.50.30.4-0.60.3-0.70.70.70.5-0.6-0.70.6-0.2-1.10.0-0.8-1.0
BMI with tail1.13.76.62.62.3-2.32.5-2.12.12.1-2.2-2.02.22.0-2.12.1-1.81.81.61.5-1.5-1.61.9-2.1-1.7-1.1-0.40.2
BMI without tail5.711.716.23.43.7-3.73.9-3.83.83.3-3.4-3.43.03.2-4.03.2-3.73.73.63.4-3.5-3.54.0-2.2-3.5-3.4-2.5-1.7
Body weight0.31.23.1-1.0-0.70.7-0.61.1-1.1-1.51.41.4-1.6-1.80.1-1.41.2-1.2-1.0-1.11.21.1-0.11.6-0.9-0.40.9-0.2
Weight adjusted by age0.60.71.5-0.5-0.70.7-0.90.9-0.8-1.21.10.7-0.6-0.61.0-0.60.9-0.9-0.9-0.90.90.7-0.80.61.01.00.70.4
Bone surface1.73.04.0-1.9-1.91.9-1.91.9-1.9-1.71.82.0-1.9-1.91.5-1.81.8-1.8-1.8-1.81.71.6-1.81.71.31.41.30.9
Bone volume2.94.97.1-2.6-2.72.7-2.72.4-2.4-1.92.02.4-2.2-2.22.4-2.22.2-2.2-2.4-2.32.12.1-2.52.01.81.81.30.7
Breakpoint value in progressive ratio session3.23.57.31.71.5-1.52.1-2.22.21.4-1.4-2.22.42.5-1.72.4-2.02.01.92.0-2.0-1.91.4-2.7-1.5-0.2-1.7-0.5
Number of licking bursts0.10.10.20.20.3-0.30.3-0.20.2-0.40.4-0.40.40.3-0.10.3-0.20.20.40.3-0.2-0.30.2-0.40.20.4-0.10.1
Context. condit. distance diff. score2.93.57.02.52.2-2.22.3-1.91.91.8-1.8-2.32.52.2-1.52.2-1.61.62.01.8-1.5-1.71.7-2.60.1-0.3-0.20.6
Locomotion velocity, session 10.10.10.5-0.5-0.50.5-0.20.2-0.2-0.60.70.2-0.4-0.30.1-0.20.2-0.2-0.0-0.40.20.10.10.70.3-0.20.20.7
Locomotion distance, session 10.10.11.00.00.1-0.10.3-0.30.2-0.10.1-0.30.40.4-0.10.4-0.20.20.20.1-0.2-0.20.1-0.4-1.00.1-0.6-0.4
Locomotion velocity, session 20.50.62.5-1.1-0.50.5-0.40.0-0.0-1.31.30.3-0.9-0.4-0.2-0.4-0.40.40.40.3-0.4-0.30.51.6-0.7-0.9-1.1-1.0
Locomotion distance, session 22.12.94.7-1.9-2.12.1-2.11.8-1.8-1.61.61.7-1.4-1.22.2-1.31.7-1.7-1.9-1.91.61.6-2.11.21.41.90.60.9
Locomotion velocity, session 30.20.31.0-0.10.3-0.30.4-0.40.4-0.40.4-0.1-0.3-0.1-1.00.1-0.60.60.60.6-0.6-0.90.80.2-0.8-0.4-0.5-0.4
Locomotion distance, session 30.20.20.4-0.0-0.10.10.4-0.50.5-0.30.2-0.40.40.6-0.50.6-0.60.60.50.6-0.6-0.50.4-0.20.20.2-0.00.4
Stereotopy head waving bouts, day 30.50.61.4-0.5-0.20.2-0.30.8-0.8-1.00.90.8-1.0-1.20.1-0.90.9-0.9-0.5-0.81.00.80.01.2-0.9-0.40.5-0.3
Stereotopy head waving duration, day 30.60.72.31.01.3-1.41.0-0.70.70.6-0.7-0.50.30.2-1.20.6-0.50.50.70.5-0.4-0.81.2-0.1-1.5-1.4-0.4-0.5
Locomotion velocity, session 72.93.26.72.41.8-1.82.2-2.02.01.3-1.5-2.22.62.6-1.52.6-1.61.61.71.5-1.5-1.41.6-2.10.3-0.20.31.6
Locomotion distance, session 72.22.86.81.81.1-1.11.6-1.81.81.7-1.8-2.12.52.6-0.82.2-1.61.61.41.4-1.6-1.30.8-2.41.30.50.01.8
Stereotopy head waving bouts, day 71.31.52.5-1.2-1.01.0-1.21.4-1.4-0.70.71.4-1.2-1.41.1-1.31.6-1.6-1.4-1.41.61.5-1.11.2-1.1-0.00.3-0.8
Stereotopy head waving duration, day 70.70.83.9-0.7-0.20.2-0.40.7-0.8-0.80.81.1-1.2-1.3-0.1-0.90.9-0.9-0.7-0.80.90.7-0.01.5-2.0-0.9-0.1-1.1
Locomotion velocity, session 80.30.41.10.80.7-0.70.8-0.50.50.5-0.5-0.91.00.9-0.20.9-0.40.40.70.5-0.3-0.50.4-1.0-0.20.2-0.2-0.1
Locomotion distance, session 80.20.31.60.50.2-0.20.4-0.20.10.2-0.2-0.50.90.80.20.70.0-0.00.2-0.10.1-0.1-0.2-1.30.71.10.51.1
Degree of sensitization distance0.40.41.30.90.6-0.60.5-0.60.61.2-1.2-0.91.11.00.10.9-0.40.40.40.2-0.4-0.30.2-1.10.20.0-0.20.3
Degree of sensitization stereotypy2.93.14.5-2.1-1.81.8-1.92.1-2.1-1.11.12.1-2.0-2.11.7-2.02.1-2.1-2.1-2.02.12.1-1.81.7-0.80.40.4-0.8
Conditioned locomotion0.20.21.30.30.2-0.20.6-0.50.5-0.0-0.0-0.1-0.0-0.0-1.10.1-0.50.50.30.3-0.4-0.30.6-0.2-0.10.10.50.7
Cocaine response after cond. corrected1.21.32.71.21.0-1.01.2-1.41.41.6-1.5-1.01.11.2-1.41.2-1.41.40.91.1-1.3-1.20.8-1.30.1-0.4-0.40.9
Cocaine response after cond. not corrected0.20.30.90.40.3-0.30.6-0.60.60.9-0.7-0.20.30.3-0.90.2-0.60.60.10.3-0.6-0.50.2-0.70.20.20.11.0
Cocaine response before conditioning2.53.04.9-1.8-1.61.6-1.72.0-2.0-1.81.92.0-2.0-2.21.3-2.21.9-1.9-1.7-1.81.91.8-1.61.60.31.31.30.3
Saline control response0.50.73.01.21.1-1.11.2-0.50.50.6-0.6-0.91.10.7-0.60.7-0.20.20.60.3-0.10.00.7-1.4-1.7-0.40.1-0.7
Bone: connectivity density0.60.93.9-0.3-0.50.5-0.40.8-0.8-1.00.90.9-0.7-0.90.1-0.70.9-0.9-0.8-1.00.90.8-0.60.41.31.31.92.0
Bone: cortical apparent density1.92.57.02.42.0-2.02.0-1.51.51.7-1.9-2.02.52.1-0.92.2-0.90.91.31.0-0.8-1.01.0-2.6-0.3-0.00.10.7
Bone: cortical area0.81.13.3-1.7-1.31.3-1.31.0-1.0-1.31.31.2-1.6-1.30.6-1.30.6-0.6-0.7-0.60.60.7-0.51.8-0.4-0.5-0.2-1.1
Bone: cortical porosity3.23.510.1-2.9-2.12.0-1.91.8-1.8-1.51.82.4-3.2-2.90.2-3.01.1-1.1-1.3-1.11.01.2-0.83.2-0.9-1.1-0.2-1.4
Bone: cortical porosity3.43.710.8-3.1-2.22.1-2.01.8-1.8-1.61.82.4-3.3-2.90.3-3.01.1-1.1-1.3-1.11.01.1-0.73.3-1.2-1.0-0.3-1.7
Bone: cortical thickness0.30.52.3-0.30.1-0.20.3-0.30.3-0.30.30.1-0.6-0.4-1.1-0.2-0.50.50.50.5-0.5-0.50.90.9-1.5-1.5-0.5-1.2
Bone: cortical thickness0.40.52.0-0.9-0.70.7-0.60.6-0.6-1.21.20.7-1.1-0.90.2-0.70.4-0.4-0.3-0.30.40.4-0.01.4-0.1-0.30.1-0.5
Bone: cortical tissue density2.22.97.62.62.1-2.12.1-1.61.61.8-2.0-2.12.62.2-1.02.3-1.01.01.41.1-0.9-1.11.1-2.8-0.3-0.00.10.8
Condit. Reinf. active minus inactive responses0.10.10.40.10.2-0.20.3-0.10.1-0.50.6-0.1-0.2-0.2-0.5-0.2-0.20.20.50.2-0.1-0.10.60.3-0.1-0.10.40.0
Condit. Reinf. active-inactive response ratio0.10.10.40.20.4-0.40.2-0.10.10.2-0.10.0-0.3-0.3-0.5-0.2-0.20.20.30.3-0.2-0.30.50.4-0.3-0.60.1-0.3
Condit. Reinf. active responses0.30.31.7-0.30.0-0.00.00.4-0.4-1.31.30.5-0.8-0.9-0.5-0.70.3-0.30.1-0.20.40.20.40.8-0.2-0.00.80.2
Condit. Reinf. inactive responses1.11.34.0-1.0-0.80.8-0.81.3-1.3-2.01.91.1-1.1-1.30.6-1.21.3-1.3-0.8-1.21.31.1-0.61.10.30.81.30.6
Incentive salience index mean0.10.20.60.40.4-0.40.5-0.20.2-0.60.6-0.30.20.1-0.50.2-0.20.20.50.2-0.1-0.20.5-0.10.40.20.70.8
Condit. Reinf. lever presses0.40.63.31.11.0-1.00.7-0.60.50.1-0.2-0.61.00.9-0.31.1-0.20.20.30.1-0.2-0.60.2-0.91.00.60.51.8
Condit. Reinf. active minus inactive responses0.70.81.7-0.6-0.60.6-0.31.0-1.0-1.31.20.9-0.8-1.10.2-0.91.1-1.1-0.7-1.11.21.3-0.40.7-0.80.81.30.3
Condit. Reinf. active-inactive response ratio0.20.22.2-0.00.2-0.20.40.2-0.2-0.90.70.2-0.2-0.4-0.4-0.10.4-0.40.1-0.30.40.40.50.4-1.5-0.10.3-0.4
Condit. Reinf. active responses2.02.85.6-1.2-1.51.5-1.21.8-1.8-1.61.61.7-1.2-1.61.3-1.52.0-2.0-1.8-2.02.12.1-1.70.80.92.22.41.6
Condit. Reinf. inactive responses2.63.25.6-1.4-1.91.9-1.81.8-1.8-1.21.41.8-1.3-1.41.8-1.51.8-1.8-2.1-1.91.82.0-2.20.92.12.42.11.8
Condit. Reinf. lever presses2.33.15.4-1.2-1.51.6-1.41.9-1.9-1.61.61.7-1.1-1.51.6-1.42.1-2.1-1.9-2.12.12.0-1.90.71.62.22.32.1
Condit. Reinf. lever reinforcers received1.92.66.3-0.9-1.31.3-1.01.7-1.7-1.51.41.6-0.9-1.41.2-1.32.0-2.0-1.8-2.02.12.1-1.70.51.02.42.51.9
Conditioned reinforcement - actives0.10.10.5-0.7-0.60.6-0.50.1-0.10.1-0.20.3-0.5-0.20.2-0.2-0.10.1-0.2-0.0-0.1-0.1-0.20.70.5-0.2-0.3-0.1
Conditioned reinforcement - inactives0.70.82.5-1.6-1.51.4-1.60.5-0.50.3-0.30.8-1.1-0.51.1-0.70.0-0.0-0.7-0.1-0.20.1-1.01.31.1-0.2-1.2-0.8
Conditioned locomotion0.70.81.8-1.3-1.31.3-1.20.8-0.9-0.90.80.7-0.6-0.41.3-0.40.8-0.8-0.7-0.80.70.7-1.01.01.21.0-0.10.3
Patch foraging indifference point 0 sec2.74.38.6-1.5-1.51.5-1.52.5-2.5-2.01.82.2-1.7-2.41.7-2.32.9-2.9-2.1-2.52.82.7-1.90.9-0.62.32.20.1
Patch foraging indifference point AUC0.20.21.20.50.3-0.30.6-0.40.40.2-0.3-0.50.70.5-0.30.8-0.20.20.30.2-0.1-0.10.4-0.50.40.20.41.1
Delay disc. indifference point, 0s delay2.32.54.01.41.4-1.31.8-1.91.90.2-0.3-2.01.72.0-1.41.9-2.02.02.01.7-1.8-1.81.9-0.8-1.0-0.7-1.6-0.6
Delay disc. indifference point, 16s delay0.60.62.00.90.8-0.71.0-0.60.60.9-0.9-0.91.00.8-0.60.7-0.70.70.70.5-0.4-0.50.6-1.4-1.40.1-0.6-1.0
Delay disc. indifference point, 2s delay0.40.42.3-0.5-0.30.30.3-0.30.3-1.51.5-0.2-0.20.1-0.70.1-0.60.60.80.5-0.6-0.70.80.7-0.50.3-0.6-0.4
Delay disc. indifference point, 24s delay0.70.71.71.21.0-1.01.3-0.80.80.7-0.7-0.81.00.8-1.20.8-0.70.70.70.5-0.4-0.60.8-1.3-0.70.20.40.5
Delay disc. indifference point, 4s delay1.71.86.20.20.6-0.60.9-1.21.30.4-0.2-1.10.50.8-1.20.6-1.71.71.61.6-1.7-1.71.4-0.2-2.1-1.4-2.3-2.5
Delay disc. indifference point, 8s delay0.30.30.80.1-0.10.10.3-0.70.70.5-0.5-0.40.20.5-0.60.3-0.80.80.50.7-0.9-0.70.4-0.3-0.5-0.1-0.8-0.7
Indifference point function ln k0.20.33.30.00.3-0.30.1-0.20.20.3-0.1-0.40.20.3-0.1-0.0-0.40.40.50.6-0.6-0.40.1-0.5-1.0-0.7-1.2-1.8
Indifference point function log k0.20.33.30.00.3-0.30.1-0.20.20.3-0.1-0.40.20.3-0.1-0.0-0.40.40.50.6-0.6-0.40.1-0.5-1.0-0.7-1.2-1.8
Patch foraging total patch changes 0 sec3.15.09.1-1.7-1.71.8-1.82.6-2.7-2.32.12.3-1.9-2.62.0-2.53.0-3.0-2.3-2.62.92.8-2.11.1-0.22.52.20.1
Patch foraging total patch changes 12 sec0.60.82.4-0.3-0.80.9-0.70.9-0.90.2-0.30.7-0.3-0.61.0-0.80.8-0.8-1.0-1.00.91.0-1.1-0.11.31.51.41.0
Patch foraging total patch changes 18 sec0.91.22.5-1.0-1.01.0-0.91.3-1.3-1.11.01.2-1.3-1.60.8-1.41.3-1.3-1.1-1.21.31.3-0.71.00.10.71.00.1
Patch foraging total patch changes 24 sec2.02.54.3-1.3-1.31.3-1.21.8-1.8-2.02.01.7-1.7-2.11.0-2.01.7-1.7-1.5-1.81.91.9-1.01.60.21.41.50.4
Patch foraging total patch changes 6 sec1.11.63.1-1.1-1.01.1-1.01.5-1.5-0.90.81.4-1.3-1.80.9-1.71.7-1.7-1.3-1.41.61.5-1.10.8-0.21.31.2-0.1
Patch foraging time to switch 0 sec1.21.83.5-1.4-1.51.5-1.41.4-1.4-0.50.41.8-1.9-1.80.8-1.80.9-0.9-1.4-1.41.21.1-1.11.61.50.41.51.3
Patch foraging water rate 0 sec0.30.43.30.40.5-0.40.2-0.10.1-0.30.4-0.71.00.80.60.60.3-0.30.40.20.00.2-0.1-0.7-1.50.5-1.0-1.8
Patch foraging water rate 12 sec3.55.310.81.62.2-2.22.0-2.42.41.7-1.4-2.51.82.0-2.01.8-2.62.62.82.8-2.7-2.62.4-1.3-2.2-2.1-3.3-3.0
Patch foraging water rate 18 sec4.76.39.92.22.7-2.72.6-2.82.81.3-1.2-2.71.92.1-2.72.3-2.72.73.12.9-2.9-2.93.2-1.1-2.4-2.4-2.6-2.4
Patch foraging water rate 24 sec5.17.19.92.52.8-2.82.5-2.93.02.2-2.1-3.12.72.8-2.02.9-2.62.63.13.1-3.0-3.02.6-2.3-1.7-2.2-2.8-2.5
Patch foraging water rate 6 sec0.60.88.2-0.40.1-0.2-0.2-0.30.3-0.10.4-0.4-0.00.10.20.1-0.20.20.70.7-0.6-0.40.50.7-1.7-1.5-2.0-2.9
Seeking ratio, delayed vs. immediate footshock0.91.12.50.91.2-1.21.1-1.01.00.1-0.1-1.61.41.4-0.41.4-0.80.81.51.1-1.0-1.11.1-0.8-0.5-1.0-1.0-0.8
Distance traveled before self-admin1.01.04.60.60.8-0.81.3-1.01.00.7-0.8-0.4-0.00.1-2.10.1-1.31.31.01.0-1.1-0.81.5-0.1-1.9-1.2-0.4-0.5
Distance traveled after self-admin0.40.44.5-0.20.1-0.10.4-0.40.40.3-0.30.3-0.6-0.5-1.3-0.2-0.30.30.10.4-0.5-0.30.60.5-2.1-0.7-0.7-0.9
Extensor digitorum longus weight0.31.11.9-1.0-0.80.8-0.81.2-1.2-1.41.31.2-1.0-1.30.7-1.11.3-1.3-1.0-1.21.31.2-0.80.9-0.60.70.8-0.1
Bone: elastic displacement0.40.43.00.00.5-0.50.5-0.20.20.00.00.1-0.5-0.6-1.1-0.3-0.30.30.50.3-0.2-0.40.90.9-1.7-1.3-0.4-1.1
Bone: elastic work0.40.53.10.30.6-0.60.9-0.50.5-0.60.5-0.0-0.3-0.3-1.80.1-0.60.60.70.5-0.5-0.71.20.5-1.4-0.50.1-0.3
Bone: endosteal estimation1.53.46.5-2.1-2.22.2-2.42.0-2.0-1.61.61.8-1.7-1.62.5-1.81.8-1.8-1.9-1.71.61.8-2.11.72.11.20.60.3
Bone: endosteal perimeter1.12.25.6-2.2-2.42.3-2.21.5-1.5-0.20.41.3-1.3-1.02.3-1.61.1-1.1-1.4-1.20.91.3-1.91.02.01.00.0-0.1
Epididymis fat weight1.12.67.20.71.2-1.31.3-1.71.71.5-1.4-1.10.30.8-2.21.0-2.22.21.72.0-2.2-2.22.0-0.0-0.8-2.7-1.6-0.7
Delta time in closed arm before/after self-admin0.70.61.6-0.6-0.90.9-1.00.9-0.90.1-0.10.7-0.5-0.61.3-0.81.0-1.0-0.9-1.00.80.9-1.10.50.80.60.60.1
Delta time in open arm before/after self-admin1.31.23.01.61.2-1.21.1-1.11.11.3-1.5-1.31.71.6-0.61.7-1.01.00.80.8-0.8-0.80.6-1.60.30.2-0.20.7
Diff in mean of infusions in LGA sessions0.50.63.2-0.6-0.00.00.1-0.20.3-0.70.70.3-0.9-0.7-1.2-0.4-0.40.40.40.6-0.6-0.50.70.8-1.8-1.3-0.9-1.3
Delay discount exponential model param0.20.21.20.30.2-0.2-0.20.1-0.10.3-0.40.00.20.10.40.20.4-0.4-0.3-0.20.30.4-0.3-0.11.1-0.10.61.0
Extinction: sum of active levers before priming0.20.21.20.40.2-0.20.3-0.40.40.9-1.1-0.20.40.3-0.30.50.1-0.1-0.10.1-0.2-0.1-0.0-0.6-1.0-0.4-0.3-0.1
Active lever presses in extinction session 62.72.63.91.41.5-1.51.8-1.71.71.5-1.5-1.91.92.0-1.31.9-1.71.71.81.5-1.4-1.41.6-1.6-1.7-1.0-1.6-0.9
Bone: final force1.42.35.1-1.8-1.81.8-1.81.6-1.6-2.22.21.4-1.6-1.51.6-1.51.4-1.4-1.1-1.31.31.3-1.11.91.10.70.7-0.1
Bone: final moment1.11.84.2-1.5-1.51.5-1.51.4-1.4-2.12.01.2-1.3-1.21.5-1.21.3-1.3-0.9-1.11.21.2-0.91.61.10.70.8-0.0
Food consumed during 24 hour testing period0.70.93.5-0.9-1.11.1-1.20.8-0.8-0.70.70.9-0.9-0.71.1-0.80.7-0.7-1.0-0.80.60.8-1.00.91.90.80.50.9
Glucose0.30.53.7-0.30.3-0.30.3-0.20.2-0.10.20.3-0.8-0.7-1.2-0.5-0.40.40.30.3-0.3-0.50.91.0-1.9-1.2-0.8-1.1
Heart weight0.10.11.30.40.3-0.30.1-0.0-0.01.1-1.1-0.20.40.10.2-0.00.0-0.00.1-0.10.10.0-0.1-0.4-0.1-0.20.3-0.1
Delay discount hyperbolic model param0.20.21.10.20.1-0.2-0.30.3-0.30.3-0.40.20.0-0.10.50.00.6-0.6-0.5-0.40.50.6-0.4-0.01.0-0.10.81.1
Intermittent access intake day 1-15 change5.55.58.8-1.9-2.22.3-2.22.6-2.7-2.52.32.2-1.4-1.72.8-1.62.9-2.9-2.6-2.93.02.9-2.81.20.62.91.81.2
Intermittent access intake escalation5.35.28.5-1.9-2.22.2-2.22.6-2.6-2.32.12.3-1.5-1.72.6-1.72.8-2.8-2.7-2.92.92.9-2.71.20.32.71.71.0
Intermittent access intake escalation 21.21.23.0-0.4-0.60.6-0.81.3-1.3-0.80.70.9-0.3-0.61.4-0.61.6-1.6-1.4-1.61.71.7-1.4-0.0-0.41.60.90.4
Intermitt. access day 1 inactive lever presses0.20.20.8-0.6-0.50.5-0.4-0.0-0.00.3-0.50.3-0.20.10.10.2-0.10.1-0.3-0.1-0.10.1-0.30.4-0.80.0-0.9-0.6
Intermitt. access day 15 inactive lever presses0.70.72.1-0.5-0.20.1-0.1-0.70.7-0.00.1-0.2-0.50.2-0.70.2-1.41.40.81.3-1.4-1.20.81.00.4-1.4-1.5-0.8
Intermitt. access escalation Index0.40.31.00.10.3-0.30.3-0.60.6-0.20.3-0.70.60.8-0.20.7-0.70.70.80.7-0.8-0.80.3-0.5-0.2-0.2-1.0-0.5
Intermittent access day 1 total infusions0.40.51.3-1.1-1.00.9-1.00.5-0.50.5-0.50.8-1.1-0.90.4-0.90.3-0.3-0.7-0.30.20.2-0.41.10.2-0.7-0.6-0.5
Intermittent access day 15 total infusions3.23.55.7-2.0-2.22.2-2.22.1-2.1-1.10.92.1-1.7-1.82.2-1.62.2-2.2-2.4-2.32.22.2-2.31.40.51.50.80.5
Intermittent access terminal intake (last 3 days)2.52.74.5-2.0-2.12.0-2.11.9-1.8-0.60.52.0-1.8-1.81.8-1.71.8-1.8-2.1-1.81.71.8-1.91.50.40.90.30.0
Intermittent access total infusions0.91.02.0-1.4-1.41.4-1.31.0-1.0-0.20.11.2-1.2-1.11.0-1.01.0-1.0-1.3-1.10.91.0-1.01.20.10.2-0.1-0.2
Intermittent access day 1 locomotion0.20.21.0-0.0-0.10.1-0.0-0.30.30.9-1.0-0.10.00.2-0.20.2-0.30.30.10.2-0.4-0.40.20.40.0-1.0-0.5-0.1
Intermittent access day 15 total locomotion1.11.22.3-1.0-1.31.3-1.31.1-1.1-0.30.11.3-1.0-1.01.1-0.91.2-1.2-1.5-1.21.11.2-1.30.91.20.60.91.2
Intermittent access total locomotion0.30.40.8-0.7-0.90.9-0.80.5-0.50.1-0.30.6-0.5-0.40.8-0.20.6-0.6-0.9-0.70.60.6-0.70.60.70.20.20.5
Intermittent access standard deviation1.41.52.6-1.4-1.41.4-1.51.4-1.5-0.30.21.3-1.0-1.11.6-1.21.4-1.4-1.5-1.51.41.5-1.61.00.30.80.40.1
Left kidney weight0.20.51.9-0.40.1-0.10.2-0.10.1-1.01.00.5-1.1-1.0-1.4-0.7-0.20.20.20.2-0.3-0.30.91.1-1.3-0.8-0.0-0.6
Right kidney weight0.20.42.5-0.20.2-0.20.40.1-0.1-0.30.30.7-1.0-1.1-1.6-0.80.1-0.1-0.1-0.20.10.00.60.5-1.5-0.80.70.3
Cocaine induced anxiety2.22.55.11.31.4-1.41.0-1.71.72.2-2.1-1.50.91.3-1.11.2-2.02.01.62.0-2.1-1.91.5-0.70.4-2.1-1.7-0.9
Post-drug Anxiety1.31.45.1-0.20.4-0.40.1-1.01.00.9-0.8-0.5-0.50.1-0.90.0-1.61.61.21.6-1.7-1.51.31.0-0.5-2.1-2.3-2.1
Baseline Anxiety2.02.14.0-2.0-1.61.6-1.41.5-1.5-2.02.01.6-1.7-1.61.0-1.71.4-1.4-1.2-1.31.41.3-1.11.7-1.40.7-0.1-1.3
Tail length0.30.84.1-0.20.5-0.50.2-0.40.50.2-0.1-0.1-0.6-0.4-1.1-0.4-0.70.70.80.8-0.8-0.71.21.1-1.5-2.0-1.2-2.0
Length with tail3.211.720.4-4.0-3.33.3-3.63.8-3.8-4.34.33.9-4.4-4.52.6-4.23.6-3.6-3.0-3.23.33.2-2.44.30.80.81.8-0.5
Length without tail8.117.629.9-4.3-4.14.1-4.14.7-4.7-5.55.44.5-4.4-4.83.7-4.44.7-4.7-4.1-4.44.64.3-3.63.82.13.03.31.5
Times rat made contact with spout0.80.92.81.41.1-1.01.2-0.90.9-0.0-0.1-1.41.71.5-0.31.6-0.60.61.00.7-0.5-0.70.7-1.50.10.30.00.4
Lifetime Intake1.01.12.3-1.5-1.51.4-1.41.1-1.10.1-0.21.3-1.3-1.21.1-1.21.0-1.0-1.3-1.10.91.0-1.11.30.2-0.0-0.1-0.2
Liver weight, left0.60.94.4-0.7-1.01.0-0.80.7-0.7-1.41.30.5-0.1-0.01.1-0.00.8-0.8-0.8-0.80.70.6-1.10.11.62.10.71.2
Liver weight, right0.60.92.8-1.2-1.21.2-1.00.9-0.8-1.71.60.8-0.9-0.80.9-0.70.7-0.7-0.5-0.60.50.5-0.61.21.50.90.40.6
Locomotor activity2.23.56.82.12.4-2.42.2-2.02.00.7-0.9-1.91.41.5-2.51.7-2.12.12.32.2-2.0-2.12.6-0.7-1.1-2.1-1.0-0.3
Locomotor testing distance3.55.810.82.73.1-3.13.0-2.62.61.5-1.7-2.31.81.8-3.32.0-2.52.52.82.6-2.4-2.53.3-1.1-2.0-2.6-1.2-0.7
Locomotor testing rearing2.94.58.62.22.4-2.32.5-2.32.22.4-2.5-1.91.51.4-2.91.5-2.22.22.12.1-2.1-2.02.6-1.5-2.5-2.1-1.2-1.1
Locomotion in novel chamber0.20.31.9-0.4-0.50.5-0.70.3-0.20.1-0.00.5-0.9-0.80.1-0.70.0-0.0-0.3-0.1-0.1-0.1-0.11.01.4-0.60.30.6
Locomotion in novel chamber post-restriction0.40.52.2-1.0-0.60.6-0.50.4-0.4-0.91.20.5-1.2-1.0-0.2-1.0-0.10.10.30.2-0.2-0.20.21.2-0.6-0.7-0.6-1.5
Fecal boli incidents, locomotor time 10.50.52.9-0.3-0.50.6-1.00.5-0.5-0.50.50.5-0.3-0.11.0-0.10.3-0.3-0.8-0.20.30.3-1.10.11.71.50.40.8
Change in fecal boli incidents, locomotor task0.90.95.1-0.30.3-0.40.40.7-0.8-0.80.60.8-0.9-1.3-0.8-0.90.9-0.9-0.2-0.91.20.90.71.4-2.3-1.40.6-0.2
Time >=10cm from walls, locomotor time 10.50.51.6-0.7-1.01.0-0.80.6-0.6-0.90.90.4-0.2-0.11.2-0.20.5-0.5-0.6-0.70.50.6-0.80.51.30.70.40.5
Bouts of movement, locomotor time 10.80.92.0-1.3-1.31.3-1.40.9-0.9-0.91.00.8-0.8-0.61.4-0.60.7-0.7-0.9-0.70.60.7-1.10.9-0.10.3-0.7-1.1
Total resting periods, locomotor time 10.50.61.2-1.1-1.00.9-1.00.7-0.7-1.01.00.7-0.8-0.60.8-0.50.5-0.5-0.6-0.50.50.5-0.71.0-0.6-0.2-0.8-1.0
Rest time, locomotor task time 10.80.93.0-1.3-0.90.9-1.20.8-0.8-1.11.11.1-1.5-1.20.5-0.90.6-0.6-0.7-0.40.40.5-0.51.7-0.7-0.7-0.6-1.0
Distance moved, locomotor task time 10.30.31.40.60.2-0.20.5-0.40.50.2-0.2-0.70.90.80.10.6-0.20.20.40.1-0.1-0.20.2-0.81.20.60.41.1
Vertical activity count, locomotor time 10.20.20.60.60.2-0.20.5-0.20.20.8-0.6-0.30.60.3-0.10.00.0-0.0-0.0-0.20.10.10.0-0.80.40.20.60.7
Time >=10cm from walls, locomotor time 20.60.62.2-0.7-1.01.0-0.80.7-0.7-1.51.40.5-0.3-0.11.1-0.10.7-0.7-0.7-0.80.70.9-0.80.70.70.80.70.6
Bouts of movement, locomotor time 21.61.83.01.31.5-1.51.4-1.41.40.4-0.5-1.61.41.4-1.11.5-1.31.31.61.3-1.3-1.31.6-1.0-1.7-1.2-1.2-1.4
Total resting periods, locomotor time 21.51.63.21.11.4-1.41.3-1.31.30.4-0.5-1.31.01.1-1.21.2-1.21.21.51.3-1.2-1.31.5-0.6-1.8-1.3-1.3-1.4
Rest time, locomotor task time 20.40.51.50.71.0-1.00.7-0.60.60.6-0.7-0.50.40.4-0.70.7-0.60.60.50.7-0.5-0.60.7-0.2-1.2-0.9-0.9-0.6
Distance moved, locomotor task time 20.20.21.60.00.0-0.00.2-0.20.2-1.11.3-0.50.40.40.20.2-0.20.20.60.2-0.2-0.20.40.10.90.00.20.1
Vertical activity count, locomotor time 20.20.21.9-0.1-0.40.4-0.10.2-0.1-0.60.8-0.20.10.00.5-0.20.1-0.10.2-0.20.10.2-0.0-0.01.40.41.00.5
Light reinforcement 10.20.32.4-0.1-0.10.1-0.1-0.20.21.5-1.5-0.1-0.1-0.0-0.0-0.3-0.50.50.10.3-0.4-0.40.10.0-0.3-0.6-0.8-1.2
Light reinforcement 21.01.34.6-2.0-1.41.3-1.31.0-1.0-0.81.01.3-2.0-1.60.3-1.80.4-0.4-0.6-0.50.40.5-0.32.1-0.6-0.8-0.5-1.2
Bone: marrow area1.53.26.3-2.1-2.22.2-2.42.0-2.0-1.51.61.8-1.8-1.62.5-1.81.8-1.8-1.8-1.71.61.7-2.01.72.01.10.50.2
Bone: maximum diameter1.22.14.7-2.2-1.91.9-1.91.5-1.5-1.51.61.6-1.9-1.71.4-1.81.2-1.2-1.2-1.21.01.3-1.22.00.20.3-0.0-0.9
Bone: maximum force2.13.65.3-2.1-2.32.3-2.22.0-2.0-2.22.21.8-1.8-1.72.1-1.81.8-1.8-1.8-1.71.61.8-1.91.62.01.81.30.7
Bone: maximum moment1.62.73.9-1.8-1.92.0-1.91.8-1.8-2.02.01.5-1.5-1.41.9-1.61.6-1.6-1.5-1.61.51.7-1.61.31.81.71.30.6
Mean time between licks in bursts0.10.10.7-0.4-0.30.3-0.3-0.10.20.10.1-0.2-0.10.10.2-0.1-0.50.50.30.5-0.6-0.50.00.10.6-0.2-0.9-0.4
Mean num. licks in bursts0.10.10.40.50.3-0.30.3-0.40.40.5-0.5-0.50.60.6-0.00.6-0.20.20.20.2-0.2-0.20.2-0.4-0.1-0.4-0.10.0
Cd content in liver1.41.62.51.21.2-1.20.9-1.31.41.3-1.2-1.51.31.6-0.61.3-1.61.61.31.6-1.6-1.50.9-1.10.3-0.5-1.4-0.7
Co content in liver0.50.62.90.30.7-0.70.5-0.50.5-0.40.4-0.60.40.5-0.50.6-0.60.60.90.7-0.6-0.70.80.0-1.6-0.3-1.2-1.7
Cu content in liver0.30.41.80.30.4-0.30.40.6-0.6-0.40.20.30.1-0.4-0.0-0.20.9-0.9-0.3-0.71.10.7-0.0-0.0-0.40.71.40.9
Fe content in liver2.93.412.7-1.3-1.41.5-1.32.0-2.0-3.63.21.3-1.1-1.42.0-1.12.2-2.2-1.3-2.02.31.9-1.21.60.72.21.60.9
K content in liver1.01.02.3-0.4-0.90.9-0.91.0-1.0-1.11.10.6-0.2-0.41.5-0.51.1-1.1-1.0-1.21.11.0-1.3-0.01.21.51.01.0
Mg content in liver1.81.82.7-1.1-1.51.5-1.61.4-1.4-1.11.31.4-1.2-1.21.6-1.31.3-1.3-1.6-1.41.31.3-1.60.91.61.31.10.9
Mn content in liver0.91.08.30.5-0.20.3-0.30.4-0.4-0.10.10.30.20.00.70.10.6-0.6-0.8-0.70.70.6-0.8-0.52.61.41.92.9
Na content in liver1.01.14.70.3-0.30.4-0.30.8-0.8-1.61.5-0.10.80.41.60.31.1-1.1-0.6-1.11.21.1-1.1-0.91.12.21.21.2
Rb content in liver0.30.31.20.50.5-0.60.5-0.60.61.0-1.1-0.30.40.5-0.70.6-0.50.50.20.4-0.5-0.40.3-0.4-0.9-0.5-0.7-0.4
Se content in liver0.50.62.10.40.1-0.10.00.6-0.60.3-0.5-0.21.10.61.30.50.9-0.9-0.7-0.91.20.9-1.0-1.3-0.21.50.50.5
Sr content in liver0.40.40.90.90.8-0.80.7-0.60.60.6-0.7-0.70.80.7-0.40.7-0.40.40.50.4-0.4-0.40.4-0.90.3-0.00.10.6
Zn content in liver0.60.72.8-0.8-0.70.7-0.60.8-0.9-0.60.60.9-0.7-0.90.5-0.81.0-1.0-0.9-1.01.01.1-0.60.8-1.7-0.30.3-1.0
Bone: minimum diameter0.50.93.1-1.7-1.31.2-1.30.7-0.7-0.60.80.7-1.4-0.90.9-1.10.1-0.1-0.2-0.1-0.10.1-0.31.80.6-0.7-0.8-1.4
Time in familiar zone, hab. session 11.61.52.51.41.6-1.61.4-1.41.40.5-0.5-1.21.21.2-1.41.4-1.31.31.11.3-1.2-1.41.2-1.1-1.0-0.6-1.0-0.3
Time in novel zone, hab. session 10.10.10.4-0.5-0.50.5-0.40.3-0.30.3-0.40.3-0.5-0.50.2-0.50.2-0.2-0.0-0.20.10.2-0.00.60.5-0.30.30.1
Total zone transitions, hab. session 10.20.31.00.30.1-0.10.40.1-0.1-1.00.9-0.50.90.70.50.80.5-0.50.2-0.40.60.50.0-0.7-0.80.60.10.0
Total locomotion distance, hab. session 10.81.13.6-0.7-1.01.0-0.61.0-1.1-1.91.70.7-0.3-0.51.1-0.41.3-1.3-0.8-1.31.31.2-0.80.30.41.51.01.1
Locomotion velocity, hab. session 11.01.44.5-1.0-1.21.2-0.81.2-1.2-2.12.00.9-0.6-0.71.2-0.61.3-1.3-1.0-1.41.41.4-1.00.60.31.50.90.8
Time in familiar zone, hab. session 20.50.61.51.21.0-0.90.9-0.80.8-0.0-0.0-1.01.21.1-0.41.1-0.60.60.70.7-0.6-0.50.6-0.8-0.30.1-0.2-0.0
Time in novel zone, hab. session 20.40.41.4-1.0-0.90.8-0.80.6-0.50.3-0.20.8-1.2-1.10.2-1.10.2-0.2-0.5-0.40.20.3-0.30.90.6-0.40.0-0.0
Total zone transitions, hab. session 20.20.31.10.60.5-0.50.6-0.30.3-0.70.6-0.71.00.80.10.9-0.00.00.40.10.0-0.00.3-0.8-1.00.3-0.3-0.5
Total locomotion distance, hab. session 20.70.93.7-0.9-0.91.0-0.71.0-1.0-1.91.80.8-0.7-0.70.8-0.71.0-1.0-0.8-1.11.11.0-0.60.6-0.41.00.40.0
Locomotion velocity, hab. session 20.70.94.0-0.7-0.80.9-0.60.9-0.9-2.01.90.8-0.5-0.60.8-0.51.1-1.1-0.9-1.21.21.0-0.70.4-0.31.30.60.3
Novel to familiar place preference ratio0.10.10.3-0.2-0.30.3-0.10.0-0.00.5-0.4-0.30.20.20.40.00.0-0.00.2-0.1-0.00.20.1-0.00.5-0.40.10.2
Novelty place preference0.10.10.3-0.1-0.20.2-0.0-0.10.10.5-0.5-0.40.30.30.30.1-0.10.10.30.1-0.20.00.2-0.00.5-0.4-0.00.2
Time in novel zone, NPP test0.10.10.6-0.2-0.20.2-0.0-0.10.10.5-0.4-0.2-0.00.10.1-0.1-0.20.20.30.1-0.2-0.00.30.20.2-0.8-0.1-0.1
Total zone transitions, NPP test0.71.02.71.21.0-1.01.2-1.01.00.1-0.2-1.21.51.5-0.51.6-0.70.70.80.6-0.5-0.70.7-1.4-1.40.1-0.8-0.3
Total locomotion distance, NPP test0.50.73.5-0.3-0.70.8-0.40.6-0.6-1.21.10.20.30.21.20.10.9-0.9-0.8-1.01.00.9-1.0-0.60.51.90.61.0
Locomotion velocity, NPP test0.50.74.00.1-0.50.5-0.20.5-0.5-1.31.20.00.60.41.10.40.9-0.9-0.6-1.00.90.8-0.9-0.80.62.00.71.4
Intraocular pressure0.20.21.40.50.7-0.70.6-0.40.40.4-0.6-0.00.20.2-0.80.6-0.10.10.10.1-0.0-0.20.50.2-1.2-0.6-0.30.4
Delta distance traveled before/after self-admin0.30.32.1-0.3-0.20.2-0.4-0.10.10.6-0.60.2-0.1-0.10.30.10.3-0.3-0.40.1-0.2-0.2-0.5-0.0-1.2-0.2-1.3-1.4
Delta ambulatory time before/after self-admin0.20.31.4-0.5-0.40.4-0.60.3-0.30.1-0.00.3-0.1-0.10.7-0.00.3-0.3-0.5-0.30.20.2-0.70.3-1.00.2-1.1-1.2
Parametrial fat weight0.71.32.41.41.3-1.31.5-1.31.30.5-0.5-1.21.21.2-1.61.4-1.21.21.21.0-1.1-1.21.2-1.2-0.7-0.6-0.10.5
Pavlov. Cond. lever latency0.91.13.61.11.0-1.01.2-0.90.91.9-1.9-1.11.10.8-0.80.8-0.80.80.90.8-0.7-0.70.8-1.5-1.3-0.9-0.4-0.9
Pavlov. Cond. magazine entry latency2.02.64.11.51.7-1.81.9-1.91.81.3-1.3-1.61.31.4-2.01.6-1.81.81.81.8-1.8-1.82.0-0.8-0.8-1.9-1.00.1
Pavlov. Cond. change in total contacts0.40.50.90.70.8-0.80.7-0.80.80.3-0.3-0.80.60.7-0.60.8-0.80.80.80.8-0.8-1.00.7-0.5-0.0-0.4-0.7-0.0
Pavlov. Cond. index score0.20.21.00.20.4-0.40.3-0.50.5-0.50.5-0.20.00.3-0.60.4-0.60.60.50.5-0.6-0.60.60.40.8-0.4-0.01.0
Pavlov. Cond. latency score0.20.21.30.20.3-0.30.3-0.40.4-0.80.7-0.20.00.3-0.50.4-0.40.40.40.3-0.4-0.50.50.40.8-0.20.11.2
Pavlov. Cond. lever contacts0.40.42.2-0.4-0.40.4-0.50.3-0.3-1.41.40.3-0.4-0.20.4-0.10.2-0.2-0.2-0.30.20.1-0.20.91.50.60.41.2
Pavlov. Cond. magazine entry number0.70.91.5-0.8-1.01.0-1.01.1-1.1-0.50.50.9-0.6-0.91.2-1.01.2-1.2-1.1-1.11.11.2-1.20.1-0.01.20.6-0.4
Pavlov. Cond. intertrial magazine entries3.74.46.4-1.9-2.22.2-2.22.4-2.4-1.92.02.0-1.6-1.92.4-2.02.5-2.5-2.3-2.52.42.4-2.41.01.22.41.90.7
Pavlov. Cond. lever-magazine prob. diff.0.20.21.00.20.3-0.30.3-0.60.5-0.20.2-0.30.20.4-0.50.5-0.70.70.40.6-0.7-0.70.40.10.9-0.2-0.21.0
Pavlov. Cond. response bias0.10.10.30.00.2-0.20.2-0.30.3-0.40.3-0.2-0.10.2-0.40.3-0.40.40.40.4-0.4-0.50.50.50.4-0.5-0.20.4
Pavlov. Cond. lever latency1.11.52.21.41.3-1.31.2-1.41.50.8-0.9-1.41.31.4-1.01.5-1.41.41.21.3-1.4-1.41.2-1.00.2-0.7-0.90.1
Pavlov. Cond. magazine entry latency0.30.44.0-0.30.0-0.10.3-0.10.10.3-0.30.0-0.2-0.2-0.8-0.2-0.30.30.40.3-0.3-0.40.40.1-2.0-0.6-0.6-1.5
Pavlov. Cond. change in total contacts0.30.40.9-0.6-0.60.6-0.40.8-0.8-0.50.50.5-0.3-0.50.7-0.60.9-0.9-0.5-0.70.90.9-0.60.4-0.80.40.4-0.6
Pavlov. Cond. index score0.30.41.1-0.8-0.60.6-0.40.7-0.8-0.10.20.7-0.5-0.70.3-0.70.7-0.7-0.6-0.70.80.7-0.60.3-1.00.40.3-0.5
Pavlov. Cond. latency score0.40.51.3-0.9-0.70.7-0.50.8-0.8-0.20.30.8-0.7-0.80.4-0.80.8-0.8-0.6-0.80.80.8-0.70.4-1.10.40.2-0.7
Pavlov. Cond. lever contacts1.21.72.6-1.4-1.41.4-1.21.5-1.5-1.01.11.4-1.2-1.41.1-1.41.5-1.5-1.4-1.51.51.6-1.30.9-0.01.11.10.2
Pavlov. Cond. magazine entry number0.20.21.70.60.3-0.30.2-0.30.30.1-0.2-0.40.60.60.20.6-0.10.1-0.00.1-0.1-0.00.0-0.51.30.10.31.2
Pavlov. Cond. intertrial magazine entries0.50.64.60.90.3-0.30.4-0.20.2-0.20.1-0.40.90.70.20.70.1-0.1-0.1-0.20.20.2-0.1-0.81.71.21.32.2
Pavlov. Cond. lever-magazine prob. diff.0.20.31.1-0.7-0.50.5-0.40.7-0.7-0.00.10.6-0.5-0.60.3-0.70.6-0.6-0.4-0.60.70.6-0.50.3-1.00.30.3-0.6
Pavlov. Cond. response bias0.40.50.8-0.9-0.80.8-0.60.8-0.8-0.50.60.9-0.8-0.90.3-0.90.8-0.8-0.7-0.80.80.8-0.60.7-0.60.50.5-0.2
Time in closed arm before self-admin0.40.51.8-0.10.4-0.50.5-0.40.4-1.11.3-0.50.00.2-0.70.2-0.60.60.90.8-0.7-0.70.90.3-0.9-0.6-1.1-1.1
Time in closed arm after self-admin1.11.25.5-1.5-0.90.9-0.90.5-0.5-2.02.30.8-1.5-1.10.1-1.20.0-0.00.10.0-0.1-0.00.12.0-0.8-0.6-1.2-1.7
Time in open arm before self-admin0.10.10.70.1-0.20.2-0.00.1-0.10.5-0.60.00.30.20.30.10.1-0.1-0.3-0.40.30.2-0.3-0.10.50.30.70.8
Time in open arm after self-admin1.01.03.21.60.8-0.80.9-0.70.71.2-1.5-1.01.61.5-0.01.6-0.50.50.30.2-0.2-0.20.2-1.51.10.80.91.8
Bone: periosteal estimation1.53.05.7-2.4-2.22.1-2.41.9-1.9-1.61.71.8-2.1-1.82.0-2.01.5-1.5-1.6-1.41.31.5-1.72.21.20.50.2-0.5
Bone: periosteal perimeter0.71.12.9-1.7-1.71.6-1.51.1-1.1-0.80.91.1-1.3-1.11.2-1.30.8-0.8-0.9-0.80.60.9-1.01.20.60.30.1-0.4
Bone: post-yield work3.54.88.7-2.5-2.82.8-2.82.4-2.4-1.41.42.1-1.8-1.72.9-2.02.2-2.2-2.4-2.22.02.3-2.81.22.52.11.21.0
Progressive ratio test 1 active lever presses0.20.20.8-0.6-0.70.6-0.4-0.10.10.5-0.60.3-0.6-0.3-0.2-0.3-0.30.3-0.20.2-0.4-0.40.10.90.1-0.7-0.7-0.3
Progressive ratio test 1 breakpoint0.20.20.7-0.6-0.50.5-0.3-0.20.20.4-0.50.2-0.5-0.1-0.3-0.1-0.40.40.00.3-0.5-0.50.20.80.0-0.7-0.8-0.3
Progressive ratio test 1 inactive lever presses0.30.31.8-0.2-0.10.1-0.1-0.50.51.3-1.4-0.1-0.00.3-0.40.3-0.70.70.00.5-0.7-0.60.00.20.1-0.7-0.9-0.1
Progressive ratio test 2 active lever presses0.30.30.8-0.8-0.90.9-0.70.2-0.20.8-0.90.7-0.8-0.60.2-0.50.0-0.0-0.7-0.2-0.10.0-0.50.50.5-0.3-0.20.2
Progressive ratio test 2 breakpoint0.20.20.8-0.5-0.60.6-0.4-0.10.10.8-0.90.3-0.4-0.2-0.1-0.1-0.30.3-0.30.1-0.3-0.3-0.10.40.6-0.5-0.40.2
Progressive ratio test 2 inactive lever presses1.01.22.8-1.5-1.41.4-1.51.2-1.1-0.40.31.4-1.5-1.41.0-1.21.0-1.0-1.2-1.10.91.0-0.91.70.3-0.10.1-0.1
Incentive Sensitization - Responses0.60.63.0-0.8-1.11.1-1.00.6-0.6-0.30.30.8-0.7-0.50.7-0.60.4-0.4-0.8-0.40.30.4-0.90.51.70.80.81.0
Incentive Sensitization - Breakpoint0.50.62.4-0.9-1.11.1-1.00.6-0.5-0.40.40.8-0.8-0.60.6-0.70.3-0.3-0.8-0.30.20.4-0.80.71.50.60.60.9
Sum of active levers in priming session hrs 5-64.44.26.62.12.3-2.32.2-2.22.21.4-1.6-2.32.22.4-1.82.6-2.12.12.22.2-2.0-2.12.1-1.8-2.0-1.3-2.1-1.3
Progressive ratio0.60.71.40.80.7-0.71.0-0.90.90.9-1.0-1.21.21.2-0.40.9-0.90.91.10.8-0.8-0.70.8-0.90.0-0.4-0.5-0.1
Food seeking constrained by brief footshock0.30.41.30.10.5-0.50.4-0.50.5-0.20.2-0.3-0.20.0-0.7-0.1-0.70.70.90.9-0.8-0.71.00.6-0.5-0.9-0.7-1.1
Seeking ratio, punishment vs. effort0.10.10.5-0.2-0.10.1-0.40.3-0.2-0.50.70.4-0.5-0.40.1-0.30.2-0.2-0.3-0.00.10.0-0.20.40.20.00.1-0.2
Retroperitoneal fat weight1.44.67.71.62.2-2.22.1-2.32.31.3-1.2-2.01.41.6-2.52.0-2.52.52.52.5-2.6-2.82.5-1.1-2.1-2.6-2.2-1.7
Reaction time number correct1.92.74.92.01.9-1.91.9-1.71.72.0-1.9-2.12.21.9-1.11.8-1.11.11.71.4-1.3-1.31.4-2.2-1.2-0.9-0.9-1.0
Reaction time mean minus median0.10.20.60.10.0-0.0-0.00.3-0.30.8-0.70.3-0.0-0.30.0-0.30.3-0.3-0.4-0.40.40.3-0.5-0.8-0.60.30.6-0.2
Reaction time mean minus median AUC0.20.21.50.40.1-0.10.10.2-0.20.9-0.9-0.10.50.20.40.20.3-0.3-0.4-0.40.40.4-0.7-1.2-0.10.60.60.2
Reaction time num false alarms0.50.73.71.10.6-0.60.8-0.60.61.3-1.3-0.91.41.1-0.11.2-0.10.10.30.2-0.2-0.2-0.0-1.90.60.70.41.1
Reaction time num false alarms AUC0.60.83.21.10.8-0.80.9-0.80.81.5-1.4-0.91.20.9-0.61.1-0.50.50.60.6-0.6-0.60.3-1.80.30.10.10.5
Reaction time trials correct on left1.92.74.92.01.9-1.91.9-1.71.72.0-1.9-2.12.21.9-1.11.8-1.11.11.71.4-1.3-1.31.4-2.2-1.2-0.9-0.9-1.0
Reaction time trials on left2.12.95.02.12.0-2.02.0-1.81.82.0-1.9-2.12.22.0-1.31.9-1.21.21.81.5-1.4-1.41.5-2.2-1.2-1.0-1.0-1.0
Reaction time mean0.10.20.70.1-0.10.10.00.1-0.10.7-0.70.20.20.1-0.0-0.00.0-0.0-0.4-0.30.20.3-0.5-0.80.30.60.70.8
Reaction time mean AUC0.10.20.90.1-0.20.20.1-0.10.10.9-0.90.00.30.2-0.20.1-0.20.2-0.3-0.1-0.00.0-0.4-0.90.20.50.40.8
Median of all reaction times0.10.20.90.30.1-0.00.2-0.20.20.7-0.7-0.10.40.4-0.20.2-0.30.3-0.10.0-0.1-0.0-0.2-0.80.50.30.41.0
Reaction time omissions0.71.02.60.30.6-0.70.8-1.01.10.3-0.1-0.6-0.10.4-1.60.2-1.61.61.11.4-1.4-1.31.40.4-0.6-1.5-1.0-0.7
Reaction time false alarm rate0.30.41.2-0.5-0.70.7-0.60.5-0.5-0.20.20.6-0.4-0.40.6-0.30.6-0.6-0.8-0.60.50.5-0.9-0.21.11.00.81.1
Reaction time premature initiation rate0.20.30.8-0.3-0.40.4-0.30.6-0.6-0.90.60.5-0.3-0.40.5-0.30.8-0.8-0.6-0.80.80.8-0.40.3-0.50.80.40.4
Reaction time premature initiations0.30.41.40.90.8-0.80.9-0.50.40.6-0.8-0.71.00.8-0.20.80.0-0.00.40.10.0-0.00.4-1.0-1.20.2-0.2-0.2
Std. dev. reaction times0.10.10.5-0.1-0.30.3-0.20.3-0.30.7-0.70.4-0.3-0.40.1-0.40.1-0.1-0.5-0.30.30.4-0.5-0.3-0.10.20.60.2
Reaction time trials completed2.12.95.02.12.0-2.02.0-1.81.82.0-1.9-2.12.22.0-1.31.9-1.21.21.81.5-1.4-1.41.5-2.2-1.2-1.0-1.0-1.0
Reaction time trials AUC1.92.74.82.11.9-1.91.9-1.71.72.1-2.0-2.12.21.9-1.21.8-1.11.11.71.5-1.3-1.41.4-2.2-1.1-0.9-0.9-1.0
Run reversals in cocaine runway, females0.20.21.10.40.2-0.20.2-0.40.40.4-0.3-0.20.10.3-0.50.3-0.60.60.20.5-0.6-0.60.2-0.11.0-0.10.50.8
Run reversals in cocaine runway, males0.30.31.40.30.2-0.20.20.2-0.3-0.50.4-0.10.50.20.40.20.6-0.6-0.2-0.40.60.8-0.2-0.30.60.81.01.2
Latency to leave start box in cocaine runway1.82.04.31.72.1-2.11.6-1.41.41.3-1.3-1.51.31.2-1.51.2-1.31.31.61.4-1.2-1.31.6-1.2-1.0-1.7-0.5-0.7
Latency to leave start box in cocaine runway, F0.70.82.80.91.2-1.30.9-0.70.71.2-1.2-0.70.50.4-0.90.4-0.70.70.90.9-0.7-0.81.0-0.5-0.8-1.7-0.4-0.9
Latency to leave start box in cocaine runway, M2.42.33.81.91.9-1.91.8-1.71.70.9-0.9-1.61.41.5-1.81.7-1.61.61.71.6-1.6-1.71.7-1.2-0.7-1.3-0.8-0.1
Std. dev. time between licks in bursts0.81.02.6-1.6-1.51.5-1.40.9-0.9-0.50.71.0-1.1-0.81.4-0.90.7-0.7-1.0-0.80.60.8-1.11.11.10.3-0.30.2
Total sessions with >9 infusions2.22.45.1-2.1-1.91.9-1.91.6-1.6-0.80.82.0-2.2-2.11.1-2.01.3-1.3-1.8-1.41.31.4-1.32.30.50.20.50.1
Short access day 1 total inactive lever presses0.40.41.5-0.5-0.30.2-0.0-0.50.51.0-1.0-0.2-0.20.2-0.40.1-0.80.80.40.8-0.9-0.70.50.7-0.1-1.2-1.2-0.7
Short access day 10 total inactive lever presses0.70.83.50.90.7-0.70.8-0.90.91.7-1.9-0.91.11.1-0.61.0-0.80.80.50.7-0.7-0.50.4-1.00.2-0.3-0.30.5
Short access day 1 total infusions0.30.31.4-0.7-0.60.6-0.60.3-0.31.2-1.10.4-0.6-0.60.2-0.80.1-0.1-0.4-0.1-0.00.1-0.30.50.3-0.7-0.1-0.4
Short access day 10 total infusions2.93.27.9-2.8-2.62.6-2.41.8-1.8-1.01.12.1-2.3-2.11.8-2.11.5-1.5-1.9-1.51.31.3-1.72.31.10.5-0.2-0.3
Short access total infusions0.70.71.7-1.3-1.21.1-1.20.9-0.90.2-0.21.0-1.0-1.00.9-1.00.8-0.8-1.0-0.80.70.7-0.81.10.5-0.2-0.1-0.2
Short access day 1 locomotion0.20.21.0-0.1-0.20.2-0.40.2-0.21.0-1.00.4-0.4-0.50.2-0.60.2-0.2-0.4-0.20.10.2-0.20.30.8-0.40.40.1
Short access day 10 total locomotion0.20.21.7-0.2-0.50.5-0.60.4-0.3-0.10.20.10.00.00.7-0.20.2-0.2-0.4-0.20.20.2-0.60.21.30.70.60.5
Short access total locomotion0.10.10.3-0.4-0.50.5-0.40.2-0.20.2-0.30.2-0.1-0.10.4-0.10.2-0.2-0.3-0.20.20.1-0.20.50.50.00.10.1
One hour access (0.3 mA shock)1.01.22.5-0.9-1.21.2-1.21.2-1.2-0.1-0.11.0-0.6-0.81.6-0.61.3-1.3-1.4-1.41.31.3-1.50.41.21.20.90.8
Compulsive drug intake0.90.93.6-0.8-1.11.1-1.30.9-0.9-0.10.20.8-0.7-0.71.4-0.70.8-0.8-1.0-0.80.60.7-1.30.41.91.00.60.6
One hour access (shock baseline)0.20.21.10.40.5-0.50.5-0.40.41.0-1.0-0.40.50.3-0.30.5-0.30.30.30.3-0.2-0.30.4-0.4-0.6-0.4-0.3-0.3
Social response proportion4.65.07.62.42.7-2.72.5-2.42.42.6-2.7-2.11.91.9-2.82.0-2.32.32.32.2-2.2-2.22.5-1.7-1.6-2.3-1.2-0.5
Social responses1.51.93.91.81.9-1.91.7-1.31.32.0-2.0-1.41.41.2-1.51.2-1.11.11.41.1-1.1-1.21.4-1.5-1.0-1.2-0.5-0.4
Social time5.87.711.12.53.0-3.02.9-3.13.12.8-2.7-2.72.02.3-3.32.1-3.33.33.23.3-3.3-3.23.2-1.7-1.4-2.9-2.2-1.3
Soleus weight0.10.41.60.70.2-0.20.4-0.30.30.5-0.6-0.71.31.10.61.10.2-0.2-0.1-0.10.20.2-0.3-1.30.20.50.10.8
Bone: stiffness1.82.95.3-2.0-2.12.2-2.11.8-1.8-2.02.11.5-1.6-1.42.1-1.61.4-1.4-1.5-1.31.31.5-1.81.22.31.81.00.5
Tibialis anterior weight0.20.82.2-0.2-0.60.7-0.30.8-0.8-1.00.90.50.0-0.30.8-0.21.2-1.2-0.9-1.21.31.2-0.8-0.20.31.51.51.2
Time to tail flick, vehicle, before self-admin0.40.42.8-0.2-0.50.5-0.70.7-0.70.3-0.00.5-0.5-0.60.8-0.70.4-0.4-0.7-0.50.60.4-0.8-0.21.70.11.00.9
Time to tail flick, vehicle, after self-admin0.91.06.80.3-0.50.5-0.20.5-0.50.6-0.50.20.2-0.10.6-0.20.5-0.5-0.7-0.80.60.7-0.8-1.02.31.02.22.6
Time to tail flick, test, before self-admin0.40.41.7-0.2-0.50.5-0.50.4-0.41.2-1.10.10.2-0.01.0-0.40.3-0.3-0.6-0.50.50.4-0.9-0.61.30.70.20.6
Time to tail flick, test, after self-admin0.91.03.50.1-0.70.8-0.80.8-0.81.5-1.20.40.1-0.21.4-0.50.6-0.6-1.1-0.90.90.9-1.5-0.81.90.91.21.3
Delta time to tail flick, vehicle, before/after SA0.80.82.7-0.4-0.70.7-0.50.9-0.9-0.1-0.00.9-0.6-0.80.5-0.71.0-1.0-1.1-1.11.01.2-0.90.20.41.01.61.3
Delta time to tail flick, test, before/after SA0.30.31.20.2-0.30.4-0.40.4-0.50.7-0.60.4-0.2-0.30.4-0.30.4-0.4-0.7-0.50.50.6-0.7-0.30.70.21.10.8
Tibia length0.61.66.0-1.1-0.70.7-0.61.3-1.3-2.52.31.3-1.6-1.70.3-1.31.4-1.4-0.7-1.11.41.1-0.02.0-1.0-0.20.8-0.3
Ambulatory time before self-admin0.60.63.70.40.5-0.51.1-0.90.90.0-0.1-0.2-0.1-0.1-1.90.0-0.80.80.80.7-0.8-0.51.3-0.0-1.7-0.6-0.1-0.1
Ambulatory time after self-admin0.20.23.1-0.1-0.00.10.4-0.40.5-0.10.10.0-0.1-0.1-0.90.0-0.20.20.20.2-0.4-0.20.50.2-1.80.1-0.7-0.5
Bone: tissue strength0.30.30.7-0.7-0.60.6-0.50.7-0.70.2-0.20.8-0.7-0.80.3-0.70.6-0.6-0.6-0.70.70.5-0.60.3-0.10.20.40.0
Total heroin consumption0.91.12.51.21.3-1.31.5-1.01.01.0-1.2-1.31.61.4-0.91.5-0.70.71.10.8-0.6-0.60.9-1.6-0.7-0.1-0.30.4
Bone: trabecular number0.71.11.7-1.0-1.11.1-1.01.0-1.0-1.21.21.2-1.2-1.20.6-1.10.9-0.9-1.0-1.00.90.8-0.81.01.31.01.21.2
Bone: trabecular spacing0.40.51.2-0.7-0.80.8-0.70.8-0.9-0.40.30.7-0.5-0.50.8-0.60.9-0.9-0.9-0.90.91.1-0.80.4-0.40.40.4-0.0
Bone: trabecular thickness0.10.11.1-0.1-0.20.2-0.30.0-0.0-0.00.00.1-0.2-0.10.1-0.1-0.10.1-0.00.1-0.1-0.2-0.10.31.10.00.20.4
Bone: trabecular tissue density0.40.52.0-0.4-0.60.6-0.70.8-0.80.7-0.70.20.1-0.11.4-0.40.9-0.9-0.7-0.70.91.0-1.1-0.6-0.40.50.1-1.0
Water consumed over 24 hours0.10.20.70.1-0.10.1-0.10.2-0.2-0.20.1-0.00.40.20.60.20.5-0.5-0.3-0.50.50.5-0.5-0.50.40.90.40.7
Number of responses in last shaping day0.60.61.30.60.8-0.80.8-0.80.80.4-0.3-0.80.40.4-0.90.4-0.90.91.01.0-0.9-1.01.1-0.3-0.6-0.9-0.7-0.7