Ehmt2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA mRNA stability Ehmt2 0.09 0.04 1.2e-06 0.06 0.08 0.08 0.08 2.9e-05 2.9e-07 9.9e-07 7.9e-07
2 RMTg intron excision ratio chr20_3931761_3931867 0.14 0.09 8.0e-03 0.03 0.03 -0.01 0 6.0e-02 4.5e-02 6.3e-01 2.9e-01
3 RMTg intron excision ratio chr20_3931791_3931867 0.14 0.09 9.4e-03 0.01 0.03 -0.01 0 1.5e-01 5.3e-02 7.3e-01 2.8e-01
4 IC gene expression Ehmt2 0.2 0.1 1.0e-06 0.14 0.12 0.1 0.13 1.7e-06 7.5e-06 8.4e-05 6.3e-06
5 pVTA gene expression Ehmt2 0.14 0.07 1.5e-09 0.1 0.1 0.09 0.1 2.3e-08 8.4e-09 1.0e-07 4.9e-08
6 NAcc gene expression Ehmt2 0.2 0.11 6.3e-14 0.09 0.09 0.09 0.09 8.4e-13 4.3e-14 4.3e-13 3.7e-13
7 Brain gene expression Ehmt2 0.11 0.06 7.9e-10 0.1 0.09 0.09 0.09 2.5e-09 1.0e-08 2.7e-08 2.3e-08
8 Brain mRNA stability Ehmt2 0.12 0.05 7.1e-13 0.15 0.14 0.14 0.14 8.6e-14 2.3e-13 5.3e-13 2.9e-13
9 BLA gene expression Ehmt2 0.33 0.12 2.1e-11 0.22 0.18 0.2 0.22 3.9e-12 8.2e-10 1.1e-10 1.1e-11
10 NAcc mRNA stability Ehmt2 0.06 0.03 1.0e-06 0.04 0.04 0.04 0.04 4.2e-06 4.4e-07 3.6e-06 3.3e-06
11 Liver alternative TSS XM_006255959.4 0.18 0.1 1.4e-03 0.05 0.04 0.04 0.04 3.6e-06 8.2e-05 4.3e-05 2.3e-05
12 Adipose isoform ratio XM_039098807.2 0.14 0.07 4.9e-11 0.08 0.1 0.07 0.1 3.1e-09 9.0e-11 1.4e-08 4.6e-11
13 OFC gene expression Ehmt2 0.16 0.1 6.0e-03 0.09 0.06 0.03 0.06 4.7e-03 1.6e-02 6.1e-02 1.9e-02
14 PL gene expression Ehmt2 0.17 0.08 7.2e-16 0.09 0.15 0.16 0.15 5.0e-10 1.3e-15 7.3e-17 2.0e-16
15 Adipose alternative TSS XM_039098807.2 0.12 0.07 2.7e-09 0.06 0.07 0.07 0.08 1.2e-07 1.2e-08 5.5e-08 6.8e-09
16 NAcc intron excision ratio chr20_3926830_3927145 0.02 0.01 9.8e-03 0.01 0 0 0 1.1e-02 9.4e-02 3.3e-01 1.4e-01
17 PL intron excision ratio chr20_3926614_3926715 0.05 0.04 1.5e-03 0.03 0.01 0.02 0.01 6.0e-04 9.7e-03 2.4e-03 3.7e-02
18 PL intron excision ratio chr20_3926830_3927145 0.07 0.04 1.2e-04 0.04 0.03 0.04 0.02 3.2e-05 3.3e-04 9.3e-05 1.4e-03
19 Eye intron excision ratio chr20_3935985_3936074 0.4 0.16 1.1e-03 0.05 0.07 0.09 0.13 6.3e-02 2.8e-02 1.9e-02 4.4e-03
20 Adipose mRNA stability Ehmt2 0.06 0.03 6.9e-06 0.06 0.05 0.05 0.07 1.7e-07 3.8e-06 3.7e-06 5.8e-08
21 Adipose gene expression Ehmt2 0.04 0.02 3.7e-04 0.04 0.03 0.03 0.03 6.2e-05 2.5e-04 6.3e-04 2.0e-04
22 BLA mRNA stability Ehmt2 0.09 0.06 9.0e-03 0.02 0.02 0.01 0.01 3.7e-02 3.0e-02 9.8e-02 1.4e-01
23 LHb mRNA stability Ehmt2 0.45 0.21 7.0e-05 0.13 0.1 0.15 0.18 4.6e-04 1.8e-03 1.8e-04 5.0e-05
24 Liver gene expression Ehmt2 0.04 0.02 2.4e-03 0 0.02 0 0 1.8e-01 3.7e-03 2.3e-01 1.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.61.03.1-1.70.2-0.10.51.11.10.80.81.1-1.10.5-1.60.50.7-1.81.0-0.90.9-1.40.4-0.2-1.0-0.4-1.3
Area under the delay curve0.10.11.30.7-0.10.1-0.2-0.2-0.20.00.0-0.70.60.3-0.2-0.10.20.10.2-0.30.31.10.2-0.3-0.1-0.5-0.1
BMI with tail1.45.09.6-2.02.2-2.2-2.6-2.2-2.5-2.2-2.2-2.5-3.0-2.61.7-2.4-3.12.1-2.82.5-2.5-1.5-3.1-0.10.2-0.31.2
BMI without tail2.37.212.0-1.12.8-2.8-3.5-3.4-3.4-3.3-3.3-3.2-1.9-3.33.2-3.3-3.33.1-2.52.4-2.41.1-2.8-1.7-0.4-1.20.8
Body weight2.410.420.5-0.02.1-2.2-3.4-3.7-3.9-3.3-3.3-3.6-1.9-3.34.0-3.4-4.14.3-4.54.4-4.40.0-3.90.51.80.63.1
Weight adjusted by age1.92.87.70.80.8-0.9-1.0-1.9-1.6-1.7-1.7-1.1-0.3-1.01.9-1.4-1.82.2-2.72.8-2.80.8-2.20.51.60.62.1
Bone surface0.10.10.30.3-0.40.4-0.00.10.00.30.30.40.1-0.20.50.0-0.20.3-0.20.3-0.3-0.2-0.10.40.50.50.5
Bone volume0.10.10.5-0.70.3-0.3-0.4-0.0-0.1-0.0-0.00.2-0.7-0.50.1-0.4-0.3-0.1-0.20.1-0.1-0.5-0.5-0.0-0.20.1-0.1
Breakpoint value in progressive ratio session0.30.30.80.4-0.60.60.70.60.40.70.70.70.70.2-0.30.70.6-0.40.9-0.80.8-0.00.60.0-0.00.4-0.3
Number of licking bursts0.91.53.41.8-1.91.81.31.21.01.51.51.11.71.2-0.41.61.1-0.50.7-0.70.70.11.31.41.11.30.7
Context. condit. distance diff. score5.06.010.51.8-3.13.13.13.13.13.03.03.22.02.9-2.12.92.5-2.01.1-1.21.2-1.91.92.62.02.50.8
Locomotion velocity, session 10.91.02.41.1-1.01.01.11.01.21.01.01.51.61.4-1.00.61.1-1.01.0-1.01.00.80.90.10.2-0.1-0.3
Locomotion distance, session 10.70.92.6-0.8-0.30.31.11.11.20.90.90.9-0.31.0-1.60.81.0-1.51.0-1.11.1-0.90.80.0-0.6-0.7-1.0
Locomotion velocity, session 20.70.81.50.8-1.11.11.11.10.91.11.10.71.11.2-1.00.70.9-0.81.0-1.21.2-0.00.80.60.20.3-0.2
Locomotion distance, session 21.11.64.2-0.2-1.11.11.71.71.61.61.61.00.11.8-2.11.41.2-1.60.8-1.11.1-1.70.91.20.40.6-0.2
Locomotion velocity, session 30.40.52.1-0.60.9-0.9-0.5-0.6-0.5-0.7-0.7-0.5-0.3-0.5-0.0-0.7-0.30.00.1-0.60.61.0-0.1-1.5-1.1-1.0-0.9
Locomotion distance, session 31.51.73.8-0.4-0.70.71.41.51.61.11.11.40.41.4-2.01.61.6-1.81.3-1.81.8-0.51.6-0.4-0.7-0.1-1.2
Stereotopy head waving bouts, day 30.50.62.41.5-0.50.5-0.2-0.5-0.7-0.1-0.1-0.60.9-0.31.30.1-0.41.3-0.70.7-0.70.80.10.61.00.41.2
Stereotopy head waving duration, day 30.70.82.71.20.2-0.2-0.8-1.1-1.1-0.9-0.9-0.70.8-0.91.7-0.6-0.61.4-0.80.9-0.91.5-0.2-0.10.5-0.30.8
Locomotion velocity, session 73.94.312.1-0.6-1.51.62.62.72.72.22.22.20.02.7-3.52.42.3-2.91.5-1.81.8-2.71.81.30.21.2-0.7
Locomotion distance, session 74.25.312.8-0.6-1.51.62.62.93.12.42.42.70.62.7-3.62.92.8-3.22.5-2.52.5-1.72.50.3-0.60.9-1.7
Stereotopy head waving bouts, day 70.60.76.10.80.2-0.2-0.4-0.6-0.5-0.4-0.4-0.41.1-0.50.7-0.4-0.10.30.8-0.80.82.50.5-1.4-1.0-1.2-0.9
Stereotopy head waving duration, day 70.50.64.20.50.4-0.5-0.7-0.9-0.9-0.7-0.7-0.70.6-0.81.0-0.7-0.50.70.1-0.20.22.00.0-1.2-0.7-1.3-0.4
Locomotion velocity, session 83.34.09.33.1-2.92.92.31.91.82.22.21.92.92.3-0.72.51.8-0.60.6-0.80.80.22.02.02.21.91.3
Locomotion distance, session 85.27.513.91.3-3.33.33.73.63.53.43.43.31.43.4-2.93.32.6-2.41.1-1.41.4-3.01.93.12.12.60.8
Degree of sensitization distance0.60.72.11.1-1.21.20.80.80.70.90.90.70.90.8-0.20.60.4-0.10.20.0-0.0-0.40.31.31.01.50.8
Degree of sensitization stereotypy0.70.73.70.40.0-0.00.00.00.10.10.10.21.0-0.0-0.1-0.10.4-0.41.2-1.31.31.90.7-1.3-1.2-1.4-1.3
Conditioned locomotion0.60.72.20.4-0.20.1-0.4-0.5-0.6-0.3-0.3-0.5-0.3-0.61.0-0.3-0.81.1-1.31.3-1.3-0.9-0.90.81.31.01.5
Cocaine response after cond. corrected0.91.05.1-0.1-1.01.01.11.10.81.01.00.6-0.50.7-0.81.10.4-0.4-0.20.3-0.3-2.30.21.81.12.00.9
Cocaine response after cond. not corrected0.50.62.91.0-1.01.00.40.30.00.50.5-0.00.40.10.50.4-0.10.6-0.60.6-0.6-0.5-0.01.51.31.71.3
Cocaine response before conditioning2.12.511.01.80.6-0.6-1.8-2.0-2.0-1.5-1.5-1.61.3-1.52.6-1.8-1.42.1-1.00.8-0.83.3-0.9-0.90.2-1.00.8
Saline control response4.76.312.7-1.73.1-3.1-3.6-3.1-2.9-3.1-3.1-3.1-1.8-3.12.3-3.0-2.52.1-1.11.5-1.52.2-2.0-2.5-1.9-2.4-0.8
Bone: connectivity density0.40.73.3-1.2-0.20.30.61.11.10.90.91.0-1.00.5-1.20.60.5-1.20.4-0.20.2-1.80.20.7-0.00.1-0.3
Bone: cortical apparent density1.31.84.2-1.81.8-1.8-1.4-1.5-1.5-1.5-1.5-1.7-2.0-1.70.8-1.4-1.60.9-0.91.0-1.00.0-1.2-1.1-1.0-0.8-0.3
Bone: cortical area0.10.10.30.5-0.20.20.0-0.3-0.50.00.0-0.40.2-0.10.4-0.1-0.40.5-0.40.1-0.10.4-0.10.00.3-0.40.4
Bone: cortical porosity1.21.311.01.00.2-0.20.1-0.4-0.2-0.2-0.20.01.70.2-0.1-0.40.4-0.31.4-1.41.43.30.7-2.0-1.3-1.6-1.4
Bone: cortical porosity1.11.110.21.5-0.30.20.4-0.20.10.10.10.42.00.6-0.0-0.10.5-0.31.3-1.11.13.20.8-1.5-0.7-1.2-0.9
Bone: cortical thickness0.71.23.9-1.61.5-1.5-0.8-1.1-1.2-1.0-1.0-1.4-1.5-1.10.1-1.0-1.10.2-0.2-0.10.10.4-0.6-1.5-1.5-2.0-1.0
Bone: cortical thickness1.72.05.5-2.01.9-1.9-1.4-1.4-1.5-1.4-1.4-2.4-2.0-1.50.4-1.5-1.50.6-0.50.3-0.30.3-1.1-1.5-1.5-1.8-0.9
Bone: cortical tissue density1.21.73.7-1.71.7-1.7-1.4-1.5-1.4-1.5-1.5-1.6-1.9-1.60.8-1.3-1.50.9-1.01.0-1.00.1-1.2-1.1-0.9-0.7-0.2
Condit. Reinf. active minus inactive responses0.91.03.20.2-0.30.30.80.70.80.70.70.70.91.1-1.40.51.0-1.31.4-1.81.80.90.8-0.7-0.9-1.0-1.2
Condit. Reinf. active-inactive response ratio0.50.52.3-0.40.8-0.8-0.4-0.6-0.7-0.6-0.6-0.8-0.1-0.3-0.1-0.6-0.3-0.10.4-0.80.81.1-0.3-1.2-1.1-1.5-0.9
Condit. Reinf. active responses0.80.93.2-0.4-0.20.20.90.91.00.80.80.70.31.2-1.80.51.1-1.51.2-1.61.6-0.10.7-0.3-0.8-0.5-1.2
Condit. Reinf. inactive responses1.11.34.2-1.4-0.10.11.01.31.41.11.11.0-0.61.1-2.10.81.3-1.91.2-1.21.2-1.41.0-0.1-0.90.1-1.3
Incentive salience index mean2.32.95.91.0-1.81.82.12.02.02.12.11.71.52.4-2.21.81.9-1.91.5-1.91.9-0.51.51.00.40.6-0.4
Condit. Reinf. lever presses4.15.79.51.4-2.93.03.03.02.93.13.12.61.53.1-2.42.82.4-2.11.0-1.21.2-2.21.82.71.92.50.8
Condit. Reinf. active minus inactive responses0.50.62.20.70.5-0.5-0.8-1.1-1.0-0.9-0.9-0.60.5-0.81.3-0.8-0.71.1-0.70.5-0.51.5-0.5-0.50.1-0.30.4
Condit. Reinf. active-inactive response ratio0.60.72.11.40.0-0.0-0.6-0.9-0.8-0.8-0.8-0.31.0-0.61.5-0.5-0.61.3-0.90.7-0.71.4-0.40.10.80.21.0
Condit. Reinf. active responses0.20.31.00.10.5-0.5-0.5-0.7-0.6-0.7-0.7-0.30.2-0.60.8-0.6-0.30.5-0.30.1-0.11.0-0.3-0.7-0.3-0.5-0.1
Condit. Reinf. inactive responses0.20.30.9-1.00.8-0.8-0.4-0.4-0.4-0.4-0.4-0.7-0.8-0.50.0-0.6-0.4-0.10.1-0.20.20.1-0.3-0.8-0.9-0.9-0.7
Condit. Reinf. lever presses0.20.31.00.00.2-0.20.30.10.40.00.00.80.60.3-0.3-0.30.4-0.50.6-0.80.81.00.1-1.0-0.7-0.9-0.9
Condit. Reinf. lever reinforcers received0.10.21.50.40.3-0.3-0.3-0.5-0.4-0.5-0.5-0.10.5-0.40.6-0.4-0.10.40.0-0.20.21.2-0.0-0.7-0.3-0.6-0.3
Conditioned reinforcement - actives0.10.21.9-0.70.7-0.7-0.5-0.3-0.2-0.6-0.6-0.0-0.5-0.2-0.1-0.40.2-0.1-0.20.2-0.2-1.4-0.1-0.2-0.30.1-0.2
Conditioned reinforcement - inactives0.10.20.6-0.50.8-0.8-0.4-0.5-0.4-0.8-0.8-0.0-0.3-0.1-0.1-0.80.1-0.1-0.30.2-0.2-0.1-0.3-0.6-0.2-0.2-0.2
Conditioned locomotion0.10.10.80.00.1-0.10.2-0.10.2-0.3-0.30.40.00.4-0.2-0.20.1-0.1-0.40.5-0.5-0.9-0.20.00.40.50.3
Patch foraging indifference point 0 sec1.83.46.3-1.42.4-2.4-2.5-2.4-2.2-2.3-2.3-2.3-1.6-2.11.4-2.5-1.71.5-1.11.2-1.20.7-1.5-1.9-1.3-1.4-0.4
Patch foraging indifference point AUC0.20.31.50.7-0.10.0-0.3-0.3-0.3-0.1-0.1-0.60.8-0.20.5-0.2-0.00.30.8-0.50.51.20.5-1.0-0.6-0.9-0.5
Delay disc. indifference point, 0s delay0.40.41.21.0-1.01.00.60.60.60.70.70.50.71.1-0.40.80.6-0.20.00.0-0.0-0.20.40.80.90.50.7
Delay disc. indifference point, 16s delay0.40.41.6-0.60.8-0.8-0.6-0.5-0.4-0.5-0.5-0.8-0.3-0.3-0.4-0.8-0.2-0.10.3-0.30.30.9-0.3-1.2-1.0-1.0-0.8
Delay disc. indifference point, 2s delay0.30.42.71.6-0.60.6-0.2-0.2-0.20.10.1-0.01.40.50.30.10.70.4-0.10.1-0.10.50.60.40.80.30.7
Delay disc. indifference point, 24s delay0.50.63.70.40.6-0.7-0.5-0.9-0.6-0.8-0.8-0.90.4-0.2-0.0-1.0-0.60.4-0.00.0-0.01.9-0.7-1.5-0.6-0.9-0.4
Delay disc. indifference point, 4s delay0.50.51.40.90.2-0.2-1.1-0.9-1.1-0.6-0.6-1.20.6-0.61.1-0.7-0.51.1-0.30.3-0.31.1-0.4-0.10.1-0.40.4
Delay disc. indifference point, 8s delay0.20.31.40.4-0.30.30.30.20.30.40.4-0.40.40.8-0.80.50.6-0.50.5-0.50.51.20.8-0.2-0.3-0.6-0.4
Indifference point function ln k0.50.81.61.2-1.21.21.20.90.81.01.00.81.31.0-0.51.01.1-0.60.6-0.90.90.31.00.70.50.80.1
Indifference point function log k0.50.81.61.2-1.21.21.20.90.81.01.00.81.31.0-0.51.01.1-0.60.6-0.90.90.31.00.70.50.80.1
Patch foraging total patch changes 0 sec1.93.66.8-1.52.5-2.5-2.5-2.4-2.2-2.4-2.4-2.4-1.7-2.11.4-2.6-1.71.4-1.01.2-1.20.8-1.5-2.1-1.4-1.5-0.5
Patch foraging total patch changes 12 sec1.82.34.4-1.11.9-1.9-2.1-1.9-1.7-1.8-1.8-2.0-1.1-1.81.3-1.9-1.51.3-0.40.7-0.71.0-1.1-2.0-1.4-1.6-0.7
Patch foraging total patch changes 18 sec1.93.07.0-2.62.4-2.4-2.1-1.7-1.7-1.9-1.9-2.3-2.6-1.90.5-1.9-1.40.6-0.50.7-0.7-0.0-1.0-1.9-1.9-1.5-1.1
Patch foraging total patch changes 24 sec0.81.45.3-2.31.7-1.7-1.0-0.6-0.4-0.9-0.9-0.9-1.8-0.6-0.8-1.2-0.5-0.70.4-0.20.2-0.3-0.5-1.7-1.9-1.8-1.6
Patch foraging total patch changes 6 sec2.03.06.1-1.62.3-2.3-2.5-2.1-1.8-2.1-2.1-2.2-1.7-1.71.0-2.3-1.71.2-0.91.0-1.00.6-1.5-1.9-1.5-1.9-0.7
Patch foraging time to switch 0 sec0.71.45.1-1.70.9-0.9-0.6-0.5-0.6-0.8-0.8-0.6-2.3-0.70.1-0.6-1.30.5-1.71.6-1.6-2.3-1.81.00.50.60.9
Patch foraging water rate 0 sec0.10.21.00.20.3-0.3-0.5-0.6-0.5-0.4-0.4-0.6-0.0-0.30.4-0.6-0.50.5-0.40.5-0.51.0-0.2-0.40.10.10.3
Patch foraging water rate 12 sec0.10.31.2-1.00.6-0.50.1-0.0-0.1-0.1-0.1-0.2-0.7-0.4-0.30.10.2-0.50.6-0.50.50.10.3-0.7-1.1-0.5-1.0
Patch foraging water rate 18 sec0.20.30.5-0.40.7-0.7-0.5-0.7-0.6-0.6-0.6-0.7-0.6-0.70.4-0.5-0.70.5-0.50.5-0.50.3-0.6-0.5-0.3-0.3-0.1
Patch foraging water rate 24 sec0.20.31.0-0.60.7-0.7-0.6-0.5-0.6-0.5-0.5-0.7-0.6-1.00.7-0.4-0.30.3-0.10.2-0.20.2-0.1-0.6-0.6-0.0-0.4
Patch foraging water rate 6 sec0.10.10.5-0.60.4-0.4-0.2-0.3-0.4-0.2-0.2-0.7-0.5-0.40.00.0-0.1-0.20.1-0.10.10.40.4-0.5-0.6-0.1-0.4
Seeking ratio, delayed vs. immediate footshock1.11.47.10.20.8-0.8-1.1-1.3-1.5-0.7-0.7-1.80.2-1.71.7-0.7-0.51.20.3-0.30.32.70.5-1.7-1.2-1.2-0.7
Distance traveled before self-admin0.40.51.70.2-0.40.40.0-0.0-0.20.20.2-0.1-0.5-0.30.7-0.1-0.50.8-1.11.2-1.2-0.6-0.50.81.21.31.3
Distance traveled after self-admin1.11.35.00.50.5-0.5-1.3-1.3-1.5-0.9-0.9-1.4-0.1-1.52.2-1.2-1.32.1-1.21.1-1.11.1-0.8-0.10.4-0.10.9
Extensor digitorum longus weight0.20.62.71.1-0.80.80.40.20.20.10.10.70.60.40.5-0.0-0.10.6-0.80.7-0.7-0.6-0.51.21.51.61.4
Bone: elastic displacement0.40.51.8-0.70.9-0.9-0.0-0.4-0.1-0.5-0.5-0.2-0.20.1-0.7-0.50.1-0.70.6-0.50.51.00.2-1.3-1.3-1.0-1.2
Bone: elastic work0.10.20.4-0.20.6-0.6-0.2-0.6-0.5-0.5-0.5-0.6-0.2-0.2-0.0-0.6-0.40.1-0.30.2-0.20.6-0.3-0.5-0.3-0.3-0.1
Bone: endosteal estimation1.73.610.63.2-1.00.9-0.9-1.2-1.4-0.8-0.8-0.31.8-0.83.0-0.7-1.22.8-2.42.3-2.31.0-1.21.63.02.43.2
Bone: endosteal perimeter1.12.49.33.0-2.12.10.70.50.21.01.00.92.10.81.11.00.21.1-1.00.9-0.9-0.10.22.42.82.32.6
Epididymis fat weight4.515.241.2-6.25.5-5.5-4.2-3.7-3.9-4.5-4.5-4.4-6.4-4.41.1-4.4-4.01.4-2.62.4-2.4-2.4-4.0-2.4-2.8-2.4-1.2
Delta time in closed arm before/after self-admin0.70.71.90.10.2-0.2-0.5-0.5-0.6-0.5-0.5-0.0-0.4-0.40.8-0.6-1.10.9-1.31.3-1.3-1.0-1.40.91.00.21.2
Delta time in open arm before/after self-admin0.20.20.8-0.70.8-0.8-0.7-0.4-0.3-0.6-0.6-0.3-0.4-0.30.1-0.7-0.0-0.10.1-0.20.20.10.0-0.2-0.7-0.9-0.6
Diff in mean of infusions in LGA sessions2.02.44.9-0.1-1.51.61.72.11.82.12.11.60.31.8-1.82.21.7-1.61.4-1.41.4-1.71.80.70.21.0-0.4
Delay discount exponential model param0.20.21.5-0.70.1-0.00.30.30.30.10.10.7-0.7-0.20.10.2-0.2-0.2-0.30.3-0.3-1.2-0.20.40.20.60.1
Extinction: sum of active levers before priming0.70.81.51.1-1.21.20.70.90.81.01.01.01.01.1-0.50.90.9-0.30.3-0.30.3-0.90.71.00.91.10.6
Active lever presses in extinction session 60.20.20.9-0.80.6-0.6-0.1-0.10.1-0.4-0.40.4-0.40.2-1.0-0.6-0.2-0.70.1-0.10.1-0.1-0.7-0.6-0.3-0.5-0.4
Bone: final force1.52.54.6-0.91.4-1.4-1.8-1.8-2.0-1.5-1.5-2.1-1.7-1.81.6-1.8-2.11.8-1.91.8-1.8-0.2-2.0-0.10.2-0.10.9
Bone: final moment1.32.13.9-0.81.4-1.4-1.7-1.7-1.8-1.5-1.5-1.8-1.5-1.71.4-1.7-2.01.6-1.81.7-1.7-0.1-1.9-0.20.2-0.10.8
Food consumed during 24 hour testing period0.70.93.20.6-0.50.5-0.1-0.1-0.40.00.0-0.4-0.2-0.10.80.2-0.51.1-1.31.3-1.3-1.2-0.61.71.71.61.8
Glucose3.25.013.73.7-3.23.22.52.02.02.22.22.63.32.4-0.52.31.6-0.40.2-0.20.20.11.42.63.02.82.0
Heart weight1.21.86.21.10.8-0.8-1.8-1.8-1.6-1.6-1.6-1.20.6-1.01.9-1.3-1.21.8-1.31.3-1.32.5-0.7-0.60.5-0.71.0
Delay discount hyperbolic model param0.20.21.7-0.80.1-0.10.40.40.40.10.10.7-0.9-0.2-0.00.2-0.3-0.3-0.40.4-0.4-1.3-0.30.40.20.60.1
Intermittent access intake day 1-15 change0.10.20.8-0.00.1-0.1-0.6-0.2-0.3-0.1-0.1-0.30.1-0.50.5-0.0-0.00.30.5-0.50.50.50.3-0.5-0.7-0.9-0.6
Intermittent access intake escalation0.40.83.4-0.70.9-0.9-1.1-0.7-0.8-0.7-0.7-0.9-0.4-1.00.5-0.6-0.30.20.7-0.80.80.70.3-1.5-1.6-1.8-1.3
Intermittent access intake escalation 20.20.20.90.4-0.20.2-0.00.20.00.20.20.10.6-0.00.10.20.2-0.00.8-0.80.80.20.5-0.3-0.5-1.0-0.6
Intermitt. access day 1 inactive lever presses0.41.44.61.7-1.61.60.90.80.41.01.00.91.00.60.71.10.40.7-0.50.6-0.6-1.40.02.12.11.81.8
Intermitt. access day 15 inactive lever presses0.20.51.30.30.3-0.3-0.8-0.7-0.7-0.6-0.6-0.3-0.1-0.51.0-0.6-0.91.0-0.90.9-0.90.5-1.10.00.60.00.8
Intermitt. access escalation Index1.62.34.10.5-1.81.81.72.01.62.02.01.50.81.6-1.42.01.6-1.51.5-1.31.3-0.91.71.40.51.6-0.1
Intermittent access day 1 total infusions0.61.03.4-0.5-0.10.10.81.01.30.40.41.60.21.6-1.80.51.5-1.80.9-1.01.0-1.10.7-0.2-0.40.2-0.9
Intermittent access day 15 total infusions0.40.62.1-0.90.7-0.7-0.6-0.00.2-0.3-0.30.2-0.20.2-0.7-0.20.6-0.81.0-1.01.0-0.20.6-1.2-1.4-1.0-1.4
Intermittent access terminal intake (last 3 days)0.30.41.5-0.60.9-0.9-0.7-0.4-0.1-0.7-0.70.1-0.00.0-0.3-0.60.2-0.50.4-0.60.60.20.2-1.2-1.1-1.1-1.1
Intermittent access total infusions0.30.41.1-0.70.7-0.7-0.3-0.00.3-0.4-0.40.5-0.10.4-0.8-0.30.7-0.90.4-0.60.6-0.40.4-1.0-0.9-0.6-1.0
Intermittent access day 1 locomotion0.10.20.8-0.90.5-0.5-0.20.00.3-0.3-0.30.3-0.70.1-0.6-0.20.1-0.5-0.20.2-0.2-0.9-0.5-0.5-0.3-0.1-0.3
Intermittent access day 15 total locomotion0.40.71.4-0.40.8-0.8-1.2-1.0-0.9-0.9-0.9-1.0-0.7-0.90.9-0.8-0.91.0-0.90.9-0.9-0.6-0.7-0.5-0.2-0.60.2
Intermittent access total locomotion0.40.51.6-0.91.0-1.0-0.9-0.8-0.5-0.9-0.9-0.5-0.8-0.60.1-0.7-0.40.2-0.50.4-0.4-1.2-0.6-0.8-0.6-0.9-0.4
Intermittent access standard deviation1.32.84.7-1.02.0-2.0-2.2-2.1-2.0-2.1-2.1-1.9-1.4-1.91.6-1.8-1.91.7-1.51.4-1.4-0.2-1.8-1.1-0.6-1.50.2
Left kidney weight2.310.717.2-0.92.9-2.9-3.8-4.0-4.1-3.8-3.8-3.7-2.3-3.84.0-3.8-4.24.0-3.93.7-3.71.0-3.9-0.90.4-0.51.9
Right kidney weight2.29.916.6-0.82.6-2.6-3.5-3.7-3.9-3.5-3.5-3.5-2.4-3.53.9-3.6-3.93.9-4.14.0-4.00.5-3.8-0.20.90.12.4
Cocaine induced anxiety0.30.41.20.6-0.90.90.50.60.30.80.80.50.30.5-0.00.70.10.2-0.1-0.00.0-0.9-0.21.00.91.10.7
Post-drug Anxiety0.20.21.20.4-0.20.2-0.5-0.2-0.5-0.1-0.1-0.20.0-0.30.7-0.1-0.10.7-0.50.4-0.4-1.1-0.20.80.70.60.7
Baseline Anxiety0.10.10.3-0.00.4-0.4-0.5-0.6-0.5-0.5-0.5-0.6-0.1-0.40.4-0.50.10.2-0.40.4-0.4-0.50.30.1-0.1-0.30.1
Tail length1.14.314.72.90.1-0.2-1.7-2.4-2.3-1.9-1.9-1.61.8-1.53.8-1.6-1.73.4-2.02.1-2.13.4-1.0-0.31.60.82.2
Length with tail1.46.216.02.80.2-0.2-1.9-2.6-2.7-2.1-2.1-2.01.1-1.64.0-2.0-2.34.0-3.43.4-3.41.7-2.01.12.71.63.5
Length without tail2.27.018.61.20.3-0.3-1.7-2.1-2.4-1.6-1.6-2.0-1.0-1.63.0-1.8-2.93.5-4.34.3-4.3-1.0-3.12.63.42.64.2
Times rat made contact with spout1.51.76.5-1.51.0-1.0-0.10.00.1-0.1-0.1-0.4-0.4-0.0-1.2-0.50.5-1.21.7-1.81.81.00.8-2.1-2.5-2.2-2.5
Lifetime Intake0.20.30.8-0.60.7-0.7-0.4-0.10.2-0.5-0.50.4-0.10.4-0.8-0.40.7-0.80.3-0.40.4-0.30.3-0.9-0.7-0.4-0.8
Liver weight, left1.21.96.52.1-1.11.10.1-0.3-0.60.00.0-0.11.0-0.21.8-0.1-1.31.8-1.81.5-1.50.3-1.51.62.52.12.5
Liver weight, right1.22.06.92.6-1.51.50.20.1-0.20.20.20.31.70.41.30.1-0.41.6-1.21.2-1.20.0-0.92.22.62.52.5
Locomotor activity0.40.72.71.30.1-0.1-0.7-1.0-1.2-0.7-0.7-0.91.0-0.81.6-0.8-0.21.4-0.50.4-0.41.3-0.1-0.40.3-0.30.6
Locomotor testing distance0.20.41.21.0-0.20.1-0.5-0.6-0.7-0.4-0.4-0.50.6-0.31.1-0.4-0.11.1-0.80.7-0.70.0-0.30.20.80.20.9
Locomotor testing rearing0.51.02.40.60.1-0.1-0.9-0.8-0.9-0.8-0.8-0.5-0.1-0.71.5-0.9-0.71.5-1.41.5-1.5-0.7-1.10.91.20.81.5
Locomotion in novel chamber0.10.11.6-0.30.2-0.2-0.5-0.2-0.3-0.2-0.2-0.4-0.2-0.30.2-0.20.10.00.2-0.20.2-1.3-0.1-0.0-0.3-0.3-0.2
Locomotion in novel chamber post-restriction0.91.42.4-0.61.3-1.3-1.4-1.5-1.5-1.5-1.5-1.5-1.2-1.41.3-1.2-1.01.4-1.51.5-1.50.3-0.6-0.20.1-0.30.7
Fecal boli incidents, locomotor time 10.30.42.9-0.70.4-0.4-0.20.10.3-0.4-0.40.9-0.60.1-0.5-0.30.5-0.6-0.60.7-0.7-1.7-0.11.00.60.20.4
Change in fecal boli incidents, locomotor task0.80.83.01.7-1.11.10.4-0.0-0.20.60.6-0.41.00.31.20.7-0.21.2-0.60.6-0.60.20.41.11.21.31.3
Time >=10cm from walls, locomotor time 12.02.16.40.9-0.30.3-0.3-0.8-1.2-0.5-0.5-1.0-0.4-1.01.9-0.6-1.42.1-2.22.3-2.3-0.8-1.51.72.11.72.5
Bouts of movement, locomotor time 10.60.71.60.2-0.70.71.30.90.71.01.00.40.40.5-0.80.90.6-0.81.1-1.21.21.00.8-0.2-0.5-0.4-0.7
Total resting periods, locomotor time 10.50.51.50.3-0.70.71.20.80.71.01.00.50.50.5-0.70.70.5-0.60.9-0.90.91.10.7-0.1-0.2-0.3-0.4
Rest time, locomotor task time 10.10.20.50.7-0.30.30.40.10.10.00.00.70.70.00.3-0.10.70.3-0.10.1-0.10.10.40.70.60.10.5
Distance moved, locomotor task time 10.20.31.2-0.20.4-0.4-0.6-0.7-0.6-0.4-0.4-1.1-0.5-0.50.2-0.5-0.80.4-0.50.4-0.40.2-0.5-0.5-0.20.10.1
Vertical activity count, locomotor time 10.30.72.9-0.80.9-0.9-1.2-1.0-1.1-0.8-0.8-1.7-1.2-0.90.5-0.6-0.80.6-0.70.7-0.7-0.4-0.6-0.3-0.5-0.40.0
Time >=10cm from walls, locomotor time 20.91.34.11.2-0.20.2-0.5-0.9-0.8-0.6-0.6-1.00.1-0.01.3-0.3-0.91.5-2.02.0-2.0-0.1-0.71.41.70.62.0
Bouts of movement, locomotor time 20.20.31.00.6-0.10.1-0.0-0.1-0.30.00.0-0.30.9-0.10.4-0.1-0.20.20.9-0.90.91.0-0.1-0.1-0.6-0.8-0.6
Total resting periods, locomotor time 20.30.42.11.1-0.60.60.40.2-0.00.40.40.01.40.10.40.10.30.11.1-1.11.11.20.30.1-0.4-0.6-0.5
Rest time, locomotor task time 21.21.54.91.4-1.71.71.61.20.91.41.41.11.00.70.11.10.80.1-0.10.2-0.2-1.30.52.21.82.01.4
Distance moved, locomotor task time 21.01.22.3-1.21.4-1.4-1.5-1.3-0.8-1.3-1.3-1.4-1.5-0.6-0.2-1.2-1.50.3-1.31.3-1.30.3-1.2-0.9-0.4-0.80.0
Vertical activity count, locomotor time 20.60.91.9-0.71.1-1.1-1.4-1.1-0.8-1.1-1.1-1.1-1.1-0.40.2-0.9-1.10.6-1.21.3-1.30.1-0.9-0.3-0.0-0.80.3
Light reinforcement 10.20.61.7-0.70.3-0.2-0.9-0.4-0.7-0.3-0.3-1.0-1.3-0.70.6-0.4-0.90.7-1.01.2-1.2-1.0-0.50.60.40.70.8
Light reinforcement 20.40.72.50.1-0.30.3-0.3-0.1-0.30.10.1-0.2-0.6-0.10.2-0.1-0.80.6-1.31.2-1.2-1.6-1.11.31.21.01.4
Bone: marrow area1.83.910.83.1-0.80.8-1.1-1.4-1.6-1.0-1.0-0.51.7-1.03.2-0.8-1.43.0-2.52.4-2.41.0-1.31.62.92.33.3
Bone: maximum diameter0.91.76.02.5-2.12.11.21.00.81.41.41.12.01.30.01.20.70.1-0.0-0.20.20.20.81.61.81.21.4
Bone: maximum force0.91.53.2-0.51.0-1.0-1.3-1.4-1.5-1.2-1.2-1.3-1.2-1.31.3-1.4-1.71.4-1.81.5-1.5-0.3-1.70.00.50.11.0
Bone: maximum moment0.71.32.9-0.30.9-0.9-1.2-1.3-1.4-1.2-1.2-0.9-0.9-1.11.2-1.3-1.51.3-1.71.5-1.5-0.2-1.6-0.00.50.21.0
Mean time between licks in bursts1.02.45.32.3-2.22.21.61.61.51.61.62.02.31.5-0.41.61.5-0.60.6-0.60.60.11.41.71.61.70.9
Mean num. licks in bursts1.62.45.9-2.42.3-2.3-1.4-1.2-1.0-1.6-1.6-1.3-1.8-1.2-0.1-1.8-0.90.00.1-0.20.20.6-0.9-2.4-2.3-2.4-1.8
Cd content in liver0.50.52.6-1.40.6-0.6-0.1-0.00.1-0.0-0.00.1-1.6-0.0-0.6-0.4-0.5-0.3-0.80.9-0.9-1.6-0.90.50.30.40.4
Co content in liver1.41.72.8-1.21.5-1.5-1.3-1.5-1.4-1.5-1.5-1.5-1.7-1.20.8-1.5-1.61.1-1.61.5-1.5-0.4-1.7-0.20.0-0.60.6
Cu content in liver1.21.45.2-1.60.7-0.70.60.30.20.70.7-0.2-0.60.1-1.30.20.7-1.21.5-2.02.00.21.0-1.6-2.2-1.3-2.3
Fe content in liver1.01.22.6-1.41.5-1.5-1.4-1.1-1.1-1.3-1.3-1.1-1.5-1.30.8-1.6-1.10.8-0.70.9-0.9-0.5-1.5-0.3-0.5-0.1-0.1
K content in liver0.70.61.5-0.0-0.80.81.21.11.01.21.21.00.20.8-0.80.80.8-0.80.7-0.70.7-0.90.50.60.00.2-0.3
Mg content in liver2.62.75.51.7-2.32.32.22.01.82.32.31.71.71.8-0.91.71.5-0.80.8-1.01.0-0.91.01.71.31.30.7
Mn content in liver2.83.17.12.4-2.62.62.21.71.52.02.01.41.81.9-0.61.91.1-0.4-0.20.0-0.0-1.00.92.42.52.71.8
Na content in liver0.50.62.0-0.40.1-0.10.00.1-0.00.40.4-0.50.1-0.3-0.10.30.4-0.41.2-1.31.31.00.9-1.2-1.4-0.6-1.4
Rb content in liver0.40.52.4-0.2-0.50.50.30.70.70.90.90.9-0.30.5-0.40.70.2-0.2-0.30.5-0.5-1.6-0.01.20.71.40.5
Se content in liver2.83.39.52.8-2.52.51.91.81.52.02.01.53.12.1-1.01.51.8-0.91.3-2.22.21.01.70.90.91.10.2
Sr content in liver0.50.41.80.40.1-0.1-0.4-0.5-0.2-0.5-0.50.0-0.0-0.30.5-0.5-0.70.7-1.01.4-1.40.1-0.90.40.80.51.0
Zn content in liver0.20.20.80.5-0.60.60.70.40.40.30.30.50.40.6-0.20.40.30.1-0.30.2-0.2-0.6-0.00.90.90.40.7
Bone: minimum diameter0.91.65.92.4-1.61.60.80.20.00.60.60.51.50.70.90.8-0.10.9-1.11.0-1.00.00.12.02.41.82.3
Time in familiar zone, hab. session 11.71.76.1-2.01.2-1.10.10.20.5-0.2-0.20.2-1.00.1-1.50.20.7-1.51.6-1.41.40.20.9-1.9-2.4-2.0-2.5
Time in novel zone, hab. session 11.31.34.41.7-0.60.5-0.7-0.7-0.8-0.3-0.3-0.40.7-0.51.7-0.5-0.91.7-1.61.5-1.50.3-1.01.21.91.22.1
Total zone transitions, hab. session 10.40.50.90.2-0.80.80.90.90.80.90.90.70.40.7-0.71.00.8-0.70.8-0.80.8-0.40.80.50.00.2-0.3
Total locomotion distance, hab. session 10.40.61.5-0.0-0.70.70.91.01.00.90.90.80.10.7-0.81.20.9-0.70.6-0.50.5-1.00.80.90.20.5-0.1
Locomotion velocity, hab. session 10.20.30.80.1-0.60.60.70.80.70.70.70.50.30.4-0.50.90.7-0.50.6-0.50.5-0.50.70.60.10.2-0.2
Time in familiar zone, hab. session 20.60.61.8-1.10.9-0.9-0.5-0.5-0.8-0.5-0.5-1.0-0.9-1.00.3-0.6-0.60.30.4-0.50.50.2-0.3-0.9-1.4-1.2-1.0
Time in novel zone, hab. session 20.10.10.30.50.1-0.1-0.5-0.3-0.0-0.3-0.30.20.40.20.1-0.3-0.10.1-0.50.6-0.60.5-0.2-0.10.50.10.5
Total zone transitions, hab. session 20.20.21.4-0.4-0.40.40.50.50.20.50.5-0.1-0.50.1-0.20.70.2-0.10.00.1-0.1-1.20.40.90.20.60.2
Total locomotion distance, hab. session 20.81.14.7-0.5-0.90.91.11.41.21.31.30.7-0.50.7-1.01.60.9-0.90.6-0.40.4-2.20.81.50.40.90.0
Locomotion velocity, hab. session 21.31.74.6-0.2-1.31.31.51.81.51.71.71.0-0.11.1-1.32.01.3-1.20.9-0.70.7-2.11.21.70.51.1-0.0
Novel to familiar place preference ratio0.10.10.60.2-0.20.20.30.30.40.30.30.40.40.3-0.30.30.4-0.50.8-0.50.50.40.5-0.3-0.40.2-0.5
Novelty place preference0.10.10.60.4-0.20.20.10.20.30.20.20.30.60.2-0.10.20.3-0.30.8-0.40.40.70.4-0.4-0.40.1-0.5
Time in novel zone, NPP test0.10.11.00.5-0.10.1-0.10.00.10.10.10.20.70.10.10.00.2-0.10.7-0.30.31.00.3-0.5-0.4-0.0-0.4
Total zone transitions, NPP test1.01.43.0-0.2-1.11.11.51.71.71.41.41.60.21.4-1.51.61.3-1.40.8-0.70.7-1.51.01.10.40.6-0.2
Total locomotion distance, NPP test1.01.46.6-0.7-0.80.81.21.61.71.11.11.4-0.61.3-1.61.51.1-1.40.2-0.10.1-2.60.51.50.70.90.2
Locomotion velocity, NPP test1.52.28.9-0.8-1.11.11.62.02.11.51.51.7-0.61.6-2.01.91.5-1.70.5-0.40.4-3.00.91.70.71.10.1
Intraocular pressure0.30.42.2-1.50.8-0.8-0.4-0.10.1-0.6-0.6-0.1-1.3-0.2-0.6-0.0-0.3-0.50.10.1-0.1-0.3-0.1-0.8-0.9-0.1-0.8
Delta distance traveled before/after self-admin1.21.33.60.51.0-1.0-1.5-1.5-1.5-1.4-1.4-1.30.6-1.21.6-1.3-0.71.3-0.10.1-0.11.9-0.3-1.2-0.7-1.4-0.3
Delta ambulatory time before/after self-admin0.70.92.90.80.6-0.6-1.1-1.3-1.2-0.9-0.9-1.20.7-1.01.5-0.9-0.61.3-0.10.0-0.01.7-0.2-0.8-0.5-1.1-0.1
Parametrial fat weight1.53.49.2-2.22.0-1.9-2.1-1.8-1.9-1.7-1.7-2.2-3.0-2.01.1-1.6-2.51.6-2.32.2-2.2-1.1-2.3-0.40.00.20.9
Pavlov. Cond. lever latency5.06.310.5-2.53.1-3.1-3.1-3.0-3.1-3.1-3.1-3.2-3.0-3.12.1-2.6-3.02.2-2.02.0-2.0-0.0-2.5-1.5-1.2-1.6-0.0
Pavlov. Cond. magazine entry latency2.73.57.72.1-2.02.02.21.81.82.02.01.72.82.2-1.41.82.1-1.62.1-2.32.31.52.30.10.00.5-0.7
Pavlov. Cond. change in total contacts1.51.64.31.7-1.51.41.41.11.11.41.41.22.11.4-0.71.21.4-0.91.3-1.51.51.21.60.20.20.6-0.3
Pavlov. Cond. index score4.65.89.82.6-3.02.93.12.72.72.92.92.63.13.0-1.92.62.7-2.12.2-2.22.20.62.61.20.91.5-0.2
Pavlov. Cond. latency score4.96.110.52.7-3.13.13.12.82.83.03.02.73.23.0-1.92.72.8-2.12.3-2.32.30.62.71.20.91.5-0.2
Pavlov. Cond. lever contacts4.65.59.12.3-3.03.03.02.82.92.92.92.92.63.0-1.92.52.6-1.91.4-1.41.4-0.62.12.11.72.10.6
Pavlov. Cond. magazine entry number1.82.34.9-1.71.7-1.7-1.9-1.5-1.5-1.6-1.6-1.5-2.2-1.81.1-1.4-1.71.4-1.71.8-1.8-1.1-1.7-0.2-0.1-0.50.6
Pavlov. Cond. intertrial magazine entries0.91.15.0-2.21.6-1.6-1.2-0.7-0.5-1.0-1.0-0.5-2.1-0.8-0.3-0.9-0.6-0.2-0.80.6-0.6-1.2-0.9-0.7-0.8-0.8-0.5
Pavlov. Cond. lever-magazine prob. diff.4.65.79.92.4-2.92.93.12.72.72.82.82.63.03.0-2.02.52.7-2.12.2-2.32.30.52.61.20.81.4-0.3
Pavlov. Cond. response bias3.24.06.82.1-2.42.42.62.22.22.42.42.22.62.5-1.62.12.3-1.81.7-2.02.00.52.11.00.81.2-0.2
Pavlov. Cond. lever latency0.40.62.20.9-0.90.90.20.30.10.40.4-0.00.20.20.40.90.20.3-0.60.7-0.7-0.90.41.51.41.41.3
Pavlov. Cond. magazine entry latency0.20.21.10.5-0.50.50.50.50.60.20.21.10.70.7-0.40.40.5-0.30.4-0.20.20.10.40.40.30.40.0
Pavlov. Cond. change in total contacts0.30.52.1-0.20.8-0.8-0.4-0.6-0.3-0.8-0.80.00.2-0.40.3-0.7-0.20.20.4-0.40.41.4-0.2-1.4-1.0-1.3-0.9
Pavlov. Cond. index score0.10.20.70.00.2-0.20.1-0.00.2-0.2-0.20.60.40.1-0.1-0.30.2-0.10.5-0.50.50.90.1-0.8-0.6-0.7-0.7
Pavlov. Cond. latency score0.10.20.8-0.10.4-0.4-0.1-0.2-0.0-0.4-0.40.30.3-0.10.0-0.5-0.00.10.4-0.30.30.9-0.1-0.8-0.6-0.7-0.6
Pavlov. Cond. lever contacts0.40.51.8-0.80.9-0.9-0.2-0.4-0.2-0.5-0.5-0.0-0.3-0.3-0.2-1.0-0.3-0.20.4-0.60.60.8-0.5-1.3-1.2-1.3-1.1
Pavlov. Cond. magazine entry number0.00.00.40.00.1-0.1-0.1-0.2-0.30.10.1-0.7-0.0-0.20.2-0.1-0.10.0-0.1-0.10.10.2-0.0-0.2-0.1-0.30.0
Pavlov. Cond. intertrial magazine entries0.71.02.11.3-1.41.41.11.10.81.41.40.61.40.9-0.41.01.0-0.71.0-1.21.20.51.10.50.30.4-0.1
Pavlov. Cond. lever-magazine prob. diff.0.10.10.6-0.10.2-0.30.1-0.00.1-0.2-0.20.50.30.1-0.2-0.30.1-0.10.5-0.40.40.70.0-0.7-0.6-0.6-0.6
Pavlov. Cond. response bias0.20.30.8-0.20.1-0.10.40.30.50.10.10.70.30.4-0.6-0.20.3-0.50.8-0.80.80.60.1-0.7-0.7-0.6-0.9
Time in closed arm before self-admin0.10.10.40.6-0.20.2-0.2-0.10.0-0.0-0.0-0.00.50.10.40.10.10.6-0.30.3-0.30.20.0-0.20.40.50.4
Time in closed arm after self-admin0.10.10.80.10.0-0.0-0.3-0.1-0.2-0.3-0.30.2-0.1-0.10.5-0.2-0.20.5-0.50.5-0.5-0.9-0.40.30.50.50.5
Time in open arm before self-admin0.80.91.80.6-0.60.61.00.70.80.80.80.91.20.9-0.80.71.0-1.01.3-1.31.31.31.2-1.0-0.5-0.1-0.9
Time in open arm after self-admin0.20.21.40.10.3-0.30.0-0.10.0-0.2-0.20.30.50.1-0.1-0.40.2-0.30.5-0.60.61.20.2-0.5-0.5-0.7-0.6
Bone: periosteal estimation1.02.05.92.2-0.50.4-0.9-1.2-1.4-0.7-0.7-0.71.1-0.92.4-0.7-1.22.3-1.91.7-1.71.0-0.90.91.91.22.3
Bone: periosteal perimeter0.50.84.22.0-1.21.20.50.1-0.10.60.60.01.50.40.70.60.00.8-0.50.4-0.40.60.31.11.50.71.4
Bone: post-yield work0.81.24.61.5-1.21.20.30.30.30.50.51.00.70.40.80.5-0.20.9-1.11.2-1.2-0.8-0.51.72.11.72.0
Progressive ratio test 1 active lever presses0.10.10.4-0.10.2-0.20.20.10.3-0.2-0.20.40.00.5-0.5-0.10.4-0.4-0.30.1-0.1-0.6-0.3-0.10.20.40.0
Progressive ratio test 1 breakpoint0.10.10.3-0.10.2-0.20.20.10.3-0.2-0.20.40.10.5-0.5-0.20.4-0.4-0.30.1-0.1-0.6-0.4-0.00.20.40.1
Progressive ratio test 1 inactive lever presses0.30.43.2-1.20.7-0.7-0.4-0.2-0.2-0.5-0.5-0.3-1.2-0.5-0.1-0.3-0.3-0.0-0.40.3-0.3-1.8-0.80.0-0.2-0.3-0.0
Progressive ratio test 2 active lever presses0.40.52.1-0.60.1-0.00.20.60.60.30.30.6-0.10.5-0.90.40.8-1.00.9-1.01.0-1.50.6-0.1-0.7-0.3-0.9
Progressive ratio test 2 breakpoint0.50.51.9-0.70.2-0.20.10.60.60.20.20.5-0.10.4-0.90.40.8-1.11.0-1.11.1-1.40.6-0.3-0.9-0.5-1.1
Progressive ratio test 2 inactive lever presses0.30.51.80.6-0.60.60.30.70.90.40.41.40.71.3-0.70.51.0-0.7-0.0-0.10.1-1.10.60.70.90.50.4
Incentive Sensitization - Responses0.50.82.4-0.1-0.40.50.40.90.60.70.70.80.50.4-0.50.91.1-0.91.5-1.51.5-1.11.40.1-0.8-0.5-1.0
Incentive Sensitization - Breakpoint0.60.72.3-0.3-0.30.40.30.90.60.70.70.70.30.3-0.60.91.0-1.01.5-1.41.4-1.21.30.0-0.8-0.5-1.1
Sum of active levers in priming session hrs 5-60.10.10.70.7-0.30.30.40.20.40.10.10.70.80.4-0.3-0.10.6-0.20.2-0.10.10.30.3-0.20.20.20.0
Progressive ratio3.65.611.4-1.02.4-2.4-2.7-3.0-3.2-2.7-2.7-3.3-1.8-3.43.2-2.6-2.72.8-2.02.1-2.11.8-2.0-1.4-0.7-1.10.5
Food seeking constrained by brief footshock0.20.30.8-0.50.7-0.7-0.9-0.4-0.2-0.7-0.7-0.4-0.2-0.3-0.0-0.9-0.1-0.00.2-0.20.2-0.4-0.4-0.5-0.7-0.8-0.6
Seeking ratio, punishment vs. effort2.43.56.51.1-1.81.82.12.32.52.02.02.51.82.5-2.41.82.3-2.11.9-1.91.9-1.31.80.90.30.2-0.7
Retroperitoneal fat weight0.10.64.4-1.20.6-0.6-0.6-0.3-0.4-0.4-0.4-0.4-1.5-0.4-0.3-0.3-0.80.2-1.10.8-0.8-2.1-0.80.30.30.60.5
Reaction time number correct1.42.64.5-1.62.1-2.1-1.9-1.9-1.8-2.0-2.0-1.8-1.8-2.01.3-1.6-2.01.2-1.41.2-1.21.2-1.7-1.4-0.9-1.3-0.2
Reaction time mean minus median1.02.44.21.3-2.02.02.01.91.91.91.92.01.62.0-1.11.91.7-1.11.3-1.01.0-0.51.41.10.71.20.0
Reaction time mean minus median AUC1.12.76.21.1-1.91.92.32.12.31.91.92.51.52.3-1.71.81.7-1.51.2-1.11.1-0.61.21.10.81.3-0.0
Reaction time num false alarms0.40.51.41.2-1.11.10.60.60.40.90.90.61.20.30.10.70.7-0.20.9-0.70.70.81.00.50.30.60.1
Reaction time num false alarms AUC0.40.62.21.5-1.11.10.50.40.10.80.80.31.50.00.40.60.60.11.0-0.90.91.41.10.10.10.2-0.0
Reaction time trials correct on left1.42.64.5-1.62.1-2.1-1.9-1.9-1.8-2.0-2.0-1.8-1.8-2.01.3-1.6-2.01.2-1.41.2-1.21.2-1.7-1.4-0.9-1.3-0.2
Reaction time trials on left1.42.64.4-1.62.1-2.1-1.9-1.9-1.7-2.0-2.0-1.7-1.8-1.91.3-1.6-1.91.2-1.41.2-1.21.2-1.7-1.4-0.9-1.2-0.2
Reaction time mean2.23.56.31.6-2.52.52.42.32.32.32.32.21.52.5-1.32.21.5-1.00.3-0.30.3-1.81.02.42.02.21.2
Reaction time mean AUC2.13.36.21.5-2.32.32.32.22.22.22.22.21.42.5-1.42.01.5-1.00.4-0.40.4-1.81.02.31.82.11.0
Median of all reaction times1.82.65.81.3-2.02.01.91.81.91.81.81.81.02.1-1.11.81.1-0.7-0.10.1-0.1-1.90.62.42.02.11.3
Reaction time omissions1.31.93.51.3-1.91.91.61.61.51.61.61.81.21.6-0.71.71.4-0.60.4-0.30.3-1.41.01.71.41.80.9
Reaction time false alarm rate1.72.46.32.4-2.22.21.51.51.21.91.91.32.51.2-0.31.51.7-0.61.7-1.51.50.91.90.80.70.90.1
Reaction time premature initiation rate0.40.62.0-0.00.5-0.5-0.8-0.7-0.5-0.8-0.8-0.3-0.5-0.60.8-0.8-0.80.8-1.41.3-1.3-0.3-1.10.30.70.31.0
Reaction time premature initiations1.42.64.7-0.91.7-1.7-1.9-1.9-1.7-2.0-2.0-1.4-1.5-1.71.6-1.7-2.01.7-2.21.9-1.90.3-2.1-0.50.2-0.50.8
Std. dev. reaction times1.73.15.72.1-2.42.42.32.02.02.12.12.12.32.3-0.92.01.8-0.91.2-1.01.0-0.11.61.51.21.50.4
Reaction time trials completed1.42.64.4-1.62.1-2.1-1.9-1.9-1.7-2.0-2.0-1.7-1.8-1.91.3-1.6-1.91.2-1.41.2-1.21.2-1.7-1.4-0.9-1.2-0.2
Reaction time trials AUC1.32.44.1-1.62.0-2.0-1.8-1.8-1.7-1.9-1.9-1.7-1.8-1.91.3-1.5-1.91.2-1.41.2-1.21.1-1.7-1.3-0.8-1.2-0.1
Run reversals in cocaine runway, females0.40.41.2-1.11.0-1.0-0.4-0.5-0.3-0.8-0.8-0.4-1.0-0.5-0.0-0.5-0.40.1-0.40.5-0.5-0.7-0.5-0.3-0.4-0.4-0.2
Run reversals in cocaine runway, males0.50.51.20.9-1.01.00.70.80.90.80.81.10.90.8-0.30.90.9-0.40.2-0.20.2-0.80.80.70.70.50.3
Latency to leave start box in cocaine runway1.21.43.51.0-1.61.61.11.41.21.51.51.20.91.3-0.61.71.0-0.60.4-0.40.4-0.51.11.41.21.90.7
Latency to leave start box in cocaine runway, F1.01.12.50.7-1.31.31.01.31.11.31.31.30.71.2-0.71.41.2-0.70.5-0.50.5-1.40.81.10.91.60.4
Latency to leave start box in cocaine runway, M0.30.31.30.6-0.70.70.30.40.20.60.60.10.30.30.10.7-0.10.1-0.20.2-0.21.10.51.00.80.80.7
Std. dev. time between licks in bursts1.72.48.72.9-2.32.31.21.11.01.41.41.62.51.30.41.00.90.3-0.00.1-0.10.40.72.12.32.11.8
Total sessions with >9 infusions0.20.21.1-0.20.6-0.6-0.1-0.3-0.0-0.5-0.5-0.00.20.3-0.4-0.50.5-0.50.4-0.30.30.50.2-1.0-0.7-0.5-0.8
Short access day 1 total inactive lever presses0.40.61.41.0-0.70.60.90.50.70.30.31.21.01.2-0.30.31.1-0.4-0.30.4-0.4-0.30.50.81.21.00.8
Short access day 10 total inactive lever presses0.30.83.20.2-1.11.10.81.10.61.21.20.60.10.4-0.11.30.7-0.20.7-0.60.6-1.80.61.60.50.70.3
Short access day 1 total infusions0.20.21.30.3-0.10.10.20.30.70.10.10.80.61.1-1.00.10.7-0.90.3-0.20.2-0.10.0-0.30.10.3-0.2
Short access day 10 total infusions0.20.30.8-0.80.5-0.5-0.00.20.4-0.2-0.20.4-0.30.5-0.9-0.20.7-0.90.4-0.50.5-0.50.1-0.5-0.70.0-0.8
Short access total infusions0.20.20.9-0.30.4-0.4-0.00.10.5-0.3-0.30.60.10.8-1.0-0.20.8-1.00.3-0.20.2-0.10.1-0.5-0.30.0-0.5
Short access day 1 locomotion0.91.12.30.2-1.01.01.21.31.21.21.21.00.51.0-1.01.21.3-1.11.1-1.11.1-1.50.80.70.01.3-0.4
Short access day 10 total locomotion0.71.34.71.5-0.20.1-0.8-1.1-1.2-0.7-0.7-1.00.6-0.92.2-0.6-1.12.1-1.31.4-1.40.3-1.20.51.10.61.5
Short access total locomotion0.20.30.80.8-0.40.40.2-0.1-0.0-0.0-0.0-0.00.30.10.50.0-0.10.5-0.70.8-0.8-0.9-0.50.60.90.80.9
One hour access (0.3 mA shock)1.82.14.4-0.2-1.11.10.91.71.51.61.61.20.41.2-1.41.91.9-1.61.8-2.02.0-2.11.90.3-0.70.3-1.2
Compulsive drug intake3.03.58.21.6-2.82.81.92.31.52.72.71.41.21.2-0.32.91.5-0.50.9-0.90.9-1.91.92.51.62.41.1
One hour access (shock baseline)0.60.92.9-1.51.4-1.4-0.8-0.4-0.0-0.9-0.9-0.0-0.80.0-0.8-0.70.3-0.80.6-0.70.70.10.1-1.7-1.7-1.3-1.7
Social response proportion0.50.62.01.1-0.10.1-0.1-0.6-0.7-0.4-0.4-0.50.60.10.9-0.4-0.41.0-1.21.0-1.00.2-0.70.91.31.01.4
Social responses0.30.41.11.00.0-0.0-0.4-0.7-0.9-0.5-0.5-0.80.7-0.21.1-0.5-0.31.0-0.60.5-0.50.9-0.20.10.60.30.8
Social time2.12.87.52.1-2.52.51.71.71.22.12.11.21.81.40.12.01.6-0.10.5-0.50.5-1.41.52.71.72.21.2
Soleus weight1.64.615.94.0-3.13.01.61.10.91.41.41.32.71.51.01.30.21.1-1.21.4-1.4-0.20.13.13.93.33.5
Bone: stiffness0.50.81.8-0.90.9-0.9-1.1-0.9-1.1-0.7-0.7-1.1-1.4-1.10.7-0.8-1.20.9-1.00.9-0.9-0.6-1.1-0.0-0.10.10.3
Tibialis anterior weight0.20.61.9-1.41.2-1.2-0.7-0.7-0.9-0.8-0.8-1.0-1.3-1.00.3-1.0-0.60.4-0.30.1-0.1-0.2-0.6-0.8-1.0-0.4-0.6
Time to tail flick, vehicle, before self-admin0.70.72.1-0.4-0.80.80.90.90.51.21.2-0.4-0.50.2-0.71.01.0-0.60.9-0.80.8-1.41.50.7-0.40.3-0.4
Time to tail flick, vehicle, after self-admin0.60.81.80.8-1.01.00.90.91.01.01.00.81.01.0-0.81.21.4-0.60.7-0.80.8-0.31.20.30.31.0-0.1
Time to tail flick, test, before self-admin0.50.51.7-0.40.3-0.3-0.3-0.1-0.20.10.1-0.6-0.1-0.5-0.10.30.1-0.31.1-1.21.20.80.5-1.2-1.3-0.8-1.2
Time to tail flick, test, after self-admin1.41.54.0-0.3-0.40.40.81.31.30.90.91.20.60.9-1.50.71.7-1.62.0-1.91.90.41.7-0.6-1.1-0.2-1.6
Delta time to tail flick, vehicle, before/after SA0.50.41.9-0.10.1-0.10.30.50.90.00.01.20.51.0-1.40.30.9-1.30.7-0.70.70.10.3-0.6-0.30.1-0.7
Delta time to tail flick, test, before/after SA0.30.31.1-0.7-0.10.10.70.70.80.30.30.9-0.50.6-1.10.10.5-0.90.2-0.10.1-0.70.20.60.10.5-0.1
Tibia length1.33.510.62.3-0.50.4-1.6-1.4-1.6-0.9-0.9-0.80.8-1.22.8-0.8-1.72.8-2.92.4-2.40.5-1.61.72.81.83.3
Ambulatory time before self-admin0.10.10.5-0.1-0.20.20.10.20.10.20.20.2-0.2-0.10.1-0.00.00.1-0.30.3-0.3-0.4-0.10.30.50.70.4
Ambulatory time after self-admin0.70.93.10.60.4-0.5-1.2-1.1-1.3-0.8-0.8-1.00.2-1.11.8-1.1-0.91.6-0.80.7-0.71.1-0.5-0.20.3-0.40.7
Bone: tissue strength0.40.41.3-0.40.5-0.5-0.5-0.4-0.3-0.6-0.60.3-0.6-0.20.2-0.6-0.70.3-1.10.9-0.9-0.5-1.10.20.50.50.6
Total heroin consumption0.10.10.20.5-0.40.40.30.2-0.00.50.50.20.5-0.10.30.20.00.20.2-0.10.10.10.0-0.10.20.20.1
Bone: trabecular number0.91.54.6-2.10.2-0.20.61.31.41.01.01.3-1.30.6-2.00.81.0-2.21.2-1.01.0-1.60.8-0.3-1.2-0.6-1.6
Bone: trabecular spacing1.31.75.01.70.1-0.1-0.8-1.5-1.6-1.2-1.2-1.50.8-0.82.1-0.9-1.42.2-1.61.4-1.41.5-1.00.31.20.21.7
Bone: trabecular thickness0.60.73.1-1.80.3-0.30.10.80.90.50.50.7-1.30.3-1.50.00.4-1.40.5-0.50.5-1.7-0.20.0-0.7-0.2-0.9
Bone: trabecular tissue density0.30.54.20.60.3-0.3-0.8-0.6-0.4-0.5-0.50.00.9-0.60.7-0.4-0.10.40.6-0.30.32.00.3-1.1-0.7-0.3-0.6
Water consumed over 24 hours0.20.20.80.9-0.80.80.50.40.20.50.50.20.70.50.10.10.20.10.0-0.10.10.00.10.70.60.70.5
Number of responses in last shaping day0.80.95.32.3-1.01.00.1-0.1-0.00.30.30.32.00.41.00.30.30.7-0.30.4-0.41.80.30.41.31.11.1