Hub : Genes

Ehd3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Ehd3 0.45 0.13 1.6e-06 0.19 0.15 0.13 0.15 3.2e-05 2.3e-04 6.6e-04 2.1e-04
2 Adipose gene expression Ehd3 0.27 0.1 3.2e-15 0.13 0.12 0.12 0.13 3.3e-14 4.1e-13 1.1e-13 2.1e-14
3 PL gene expression Ehd3 0.11 0.05 1.4e-08 0.11 0.09 0.1 0.11 1.3e-11 4.9e-10 1.2e-10 1.2e-11
4 pVTA gene expression Ehd3 0.24 0.08 4.5e-13 0.17 0.17 0.16 0.16 1.5e-13 1.8e-13 9.5e-13 5.9e-13
5 Brain gene expression Ehd3 0.24 0.11 5.1e-10 0.13 0.11 0.13 0.13 4.4e-12 1.8e-10 4.6e-12 7.2e-12
6 IC gene expression Ehd3 0.15 0.07 2.3e-04 0.04 0.07 0.06 0.06 1.0e-02 5.3e-04 2.2e-03 2.3e-03
7 BLA gene expression Ehd3 0.1 0.05 3.2e-04 0.05 0.06 0.06 0.06 1.3e-03 5.9e-04 5.2e-04 6.3e-04
8 NAcc gene expression Ehd3 0.26 0.09 0.0e+00 0.14 0.12 0.14 0.14 8.4e-20 3.5e-18 4.1e-20 2.0e-20
9 IL mRNA stability Ehd3 0.38 0.17 1.3e-03 0.04 0.13 0.07 0.09 3.8e-02 5.6e-04 7.7e-03 3.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density4.37.49.5-2.72.9-2.8-2.9-2.8-2.6-2.2-3.1-2.4
Area under the delay curve2.73.25.3-1.71.9-1.6-1.9-2.0-1.2-1.2-1.9-2.3
BMI with tail0.20.63.40.1-0.30.00.10.0-1.3-0.00.31.9
BMI without tail0.30.83.70.8-0.60.80.70.5-1.00.20.71.9
Body weight1.35.69.12.6-2.62.52.42.21.02.12.53.0
Weight adjusted by age0.40.71.1-1.00.9-0.9-0.8-0.6-0.7-0.3-0.8-1.0
Bone surface1.93.54.5-1.92.0-1.8-1.9-1.9-1.6-1.6-2.1-1.9
Bone volume2.13.75.2-1.92.1-1.8-2.0-2.1-1.6-1.6-2.3-1.9
Breakpoint value in progressive ratio session0.30.31.3-0.50.4-0.8-0.3-0.2-0.6-0.60.01.1
Number of licking bursts0.30.41.30.9-0.40.60.40.40.10.70.71.1
Context. condit. distance diff. score0.60.71.01.0-1.01.00.80.70.90.80.90.6
Locomotion velocity, session 10.70.82.5-0.70.9-0.7-0.7-0.8-1.6-0.8-1.0-0.4
Locomotion distance, session 11.31.73.6-1.21.3-1.3-1.2-1.2-1.9-0.8-1.4-0.9
Locomotion velocity, session 20.50.61.0-0.50.8-0.9-0.7-0.6-1.0-0.8-0.7-1.0
Locomotion distance, session 20.50.72.1-0.90.6-0.9-0.6-0.6-1.5-0.7-0.70.1
Locomotion velocity, session 32.83.24.3-1.82.1-1.9-1.8-1.7-2.0-1.2-2.0-1.7
Locomotion distance, session 31.71.83.3-1.41.4-1.5-1.4-1.4-1.8-1.4-1.1-0.3
Stereotopy head waving bouts, day 31.92.22.7-1.61.4-1.4-1.6-1.6-1.0-1.6-1.4-1.6
Stereotopy head waving duration, day 31.01.21.9-1.21.0-1.0-1.2-1.2-0.5-1.0-1.1-1.4
Locomotion velocity, session 72.42.76.8-1.51.6-1.8-1.7-1.7-2.6-1.0-1.60.1
Locomotion distance, session 70.20.21.3-0.30.2-0.3-0.3-0.4-1.10.0-0.30.3
Stereotopy head waving bouts, day 70.10.10.60.10.1-0.00.00.10.5-0.2-0.2-0.8
Stereotopy head waving duration, day 70.80.93.1-0.51.0-0.7-0.8-0.8-0.5-0.7-1.2-1.8
Locomotion velocity, session 81.82.15.5-1.21.4-1.3-1.5-1.4-2.3-1.6-1.3-0.4
Locomotion distance, session 80.10.10.4-0.1-0.2-0.0-0.0-0.1-0.60.00.10.5
Degree of sensitization distance1.41.52.41.2-1.31.31.21.20.91.51.10.8
Degree of sensitization stereotypy0.20.20.50.5-0.40.40.60.60.70.60.4-0.1
Conditioned locomotion1.72.02.5-1.51.4-1.6-1.5-1.5-1.4-0.9-1.5-1.3
Cocaine response after cond. corrected1.11.32.4-1.01.2-0.8-1.0-0.9-1.3-0.6-1.4-1.6
Cocaine response after cond. not corrected1.51.82.6-1.11.5-1.1-1.3-1.2-1.6-0.9-1.6-1.6
Cocaine response before conditioning0.40.51.0-0.50.8-0.9-0.8-0.9-0.4-1.0-0.5-0.2
Saline control response1.01.42.9-1.51.1-1.7-1.3-1.1-0.2-1.6-0.70.1
Bone: connectivity density4.97.69.3-2.73.0-2.8-2.8-2.8-2.7-2.2-3.0-2.6
Bone: cortical apparent density0.50.71.5-1.00.9-0.9-0.8-0.7-0.7-1.2-0.8-0.2
Bone: cortical area0.20.40.5-0.70.7-0.7-0.7-0.7-0.4-0.3-0.7-0.2
Bone: cortical porosity1.01.16.6-0.20.7-0.1-0.3-0.4-0.20.9-1.2-2.6
Bone: cortical porosity1.01.17.0-0.20.6-0.1-0.2-0.3-0.00.9-1.1-2.6
Bone: cortical thickness0.10.10.20.2-0.30.20.30.30.50.50.20.4
Bone: cortical thickness0.20.30.6-0.40.5-0.4-0.3-0.4-0.60.4-0.6-0.8
Bone: cortical tissue density0.40.61.3-0.90.8-0.8-0.7-0.6-0.5-1.2-0.7-0.1
Condit. Reinf. active minus inactive responses1.31.44.11.0-1.21.31.21.10.01.01.12.0
Condit. Reinf. active-inactive response ratio0.20.21.3-0.0-0.10.40.20.2-0.30.10.11.1
Condit. Reinf. active responses0.50.61.80.5-0.70.70.70.7-0.60.90.61.3
Condit. Reinf. inactive responses0.10.10.50.1-0.10.10.20.1-0.70.70.1-0.2
Incentive salience index mean0.20.20.80.2-0.30.40.40.3-0.60.70.20.9
Condit. Reinf. lever presses0.30.40.7-0.70.7-0.6-0.5-0.5-0.80.3-0.7-0.8
Condit. Reinf. active minus inactive responses0.00.10.20.2-0.3-0.00.10.1-0.40.10.30.4
Condit. Reinf. active-inactive response ratio0.00.00.10.1-0.00.1-0.1-0.1-0.30.30.0-0.2
Condit. Reinf. active responses0.00.10.20.2-0.40.10.20.20.00.10.30.4
Condit. Reinf. inactive responses0.00.00.1-0.20.0-0.4-0.2-0.1-0.1-0.3-0.10.3
Condit. Reinf. lever presses0.10.10.7-0.1-0.2-0.1-0.0-0.0-0.6-0.10.20.9
Condit. Reinf. lever reinforcers received0.00.10.20.1-0.30.00.10.2-0.30.10.20.5
Conditioned reinforcement - actives0.30.61.1-1.00.6-0.7-0.9-1.00.2-0.9-0.60.6
Conditioned reinforcement - inactives0.60.91.7-0.91.1-0.9-0.8-0.8-1.1-1.3-1.00.2
Conditioned locomotion0.50.72.3-0.80.3-0.9-0.4-0.40.4-1.50.31.2
Patch foraging indifference point 0 sec0.10.10.80.30.00.40.10.1-0.10.0-0.3-0.9
Patch foraging indifference point AUC0.81.21.9-1.31.2-1.0-1.4-1.4-0.9-0.9-0.90.1
Delay disc. indifference point, 0s delay0.91.01.71.1-0.81.31.01.01.01.30.7-0.6
Delay disc. indifference point, 16s delay2.12.34.9-1.41.7-1.3-1.6-1.6-1.1-0.7-1.6-2.2
Delay disc. indifference point, 2s delay1.31.54.8-0.91.3-0.8-1.2-1.1-0.7-0.5-1.4-2.2
Delay disc. indifference point, 24s delay5.66.38.3-2.62.8-2.4-2.8-2.9-2.0-1.7-2.7-2.5
Delay disc. indifference point, 4s delay2.02.16.7-0.91.5-0.5-1.3-1.5-1.0-0.6-1.9-2.6
Delay disc. indifference point, 8s delay2.22.63.4-1.81.6-1.7-1.7-1.7-1.4-1.3-1.4-1.5
Indifference point function ln k0.10.20.70.6-0.40.30.40.50.50.5-0.3-0.9
Indifference point function log k0.10.20.70.6-0.40.30.40.50.50.5-0.3-0.9
Patch foraging total patch changes 0 sec0.10.10.30.4-0.10.60.30.3-0.10.3-0.1-0.6
Patch foraging total patch changes 12 sec0.10.10.3-0.40.3-0.1-0.4-0.4-0.4-0.1-0.5-0.3
Patch foraging total patch changes 18 sec0.20.30.8-0.40.7-0.4-0.5-0.5-0.7-0.9-0.3-0.4
Patch foraging total patch changes 24 sec0.10.20.60.4-0.20.40.30.30.7-0.10.3-0.5
Patch foraging total patch changes 6 sec0.10.10.2-0.20.30.1-0.3-0.3-0.20.3-0.3-0.4
Patch foraging time to switch 0 sec0.40.91.7-1.10.9-1.1-0.9-0.9-1.3-0.9-0.5-0.6
Patch foraging water rate 0 sec0.10.30.60.6-0.30.60.50.50.80.7-0.1-0.3
Patch foraging water rate 12 sec1.32.74.72.2-1.42.01.81.81.42.00.9-0.4
Patch foraging water rate 18 sec0.60.92.21.2-0.90.80.90.91.51.10.80.1
Patch foraging water rate 24 sec1.11.52.21.4-1.41.31.11.01.51.21.30.7
Patch foraging water rate 6 sec0.60.81.41.2-0.70.91.01.00.91.20.3-0.8
Seeking ratio, delayed vs. immediate footshock0.20.31.8-0.40.2-0.2-0.4-0.2-0.1-1.3-0.10.3
Distance traveled before self-admin0.70.91.21.0-1.00.91.11.00.70.91.10.7
Distance traveled after self-admin1.11.31.91.3-1.10.91.11.11.41.31.11.1
Extensor digitorum longus weight2.28.812.4-3.13.0-3.3-3.2-3.2-3.5-3.2-2.3-0.7
Bone: elastic displacement0.10.10.4-0.60.2-0.3-0.5-0.4-0.10.3-0.4-0.0
Bone: elastic work0.50.61.1-1.00.7-0.9-0.9-0.9-0.8-0.1-0.9-0.5
Bone: endosteal estimation0.40.81.0-1.01.0-0.7-1.0-1.0-1.0-0.6-1.0-0.8
Bone: endosteal perimeter0.20.50.7-0.80.6-0.7-0.8-0.90.1-0.8-0.5-0.2
Epididymis fat weight4.816.621.54.4-4.64.44.24.24.63.93.71.9
Delta time in closed arm before/after self-admin0.30.32.20.1-0.10.30.30.3-0.00.4-0.0-1.5
Delta time in open arm before/after self-admin1.01.01.9-0.81.0-0.9-1.0-1.1-1.4-1.4-0.70.5
Diff in mean of infusions in LGA sessions0.10.10.6-0.30.4-0.50.10.00.2-0.8-0.3-0.1
Delay discount exponential model param3.74.16.02.0-2.21.82.22.21.61.42.12.4
Extinction: sum of active levers before priming0.10.10.40.10.20.3-0.1-0.1-0.60.5-0.20.1
Active lever presses in extinction session 60.20.20.70.20.30.1-0.4-0.40.70.2-0.9-0.5
Bone: final force0.81.33.2-0.91.3-0.8-1.0-1.0-0.9-0.3-1.6-1.8
Bone: final moment0.81.22.8-0.81.3-0.8-0.9-0.9-1.0-0.3-1.6-1.7
Food consumed during 24 hour testing period0.10.10.40.2-0.30.20.30.30.60.30.6-0.2
Glucose0.91.52.11.0-1.41.21.31.31.20.41.41.4
Heart weight1.62.54.61.9-1.72.11.81.81.11.61.1-0.1
Delay discount hyperbolic model param3.03.35.61.8-1.91.61.92.01.31.31.92.4
Intermittent access intake day 1-15 change0.61.21.71.1-1.01.31.11.21.31.30.8-0.3
Intermittent access intake escalation0.71.52.41.4-1.11.51.31.41.31.41.0-0.4
Intermittent access intake escalation 22.83.24.22.0-1.82.02.01.91.81.81.50.8
Intermitt. access day 1 inactive lever presses0.51.84.2-1.91.1-1.6-1.4-1.2-1.0-2.1-0.3-0.1
Intermitt. access day 15 inactive lever presses0.00.10.4-0.00.1-0.00.10.3-0.3-0.60.20.2
Intermitt. access escalation Index0.10.10.4-0.1-0.10.3-0.2-0.40.10.5-0.20.6
Intermittent access day 1 total infusions1.22.02.8-1.71.4-1.7-1.4-1.4-1.5-1.5-1.00.9
Intermittent access day 15 total infusions0.10.10.2-0.40.5-0.4-0.3-0.3-0.4-0.4-0.20.1
Intermittent access terminal intake (last 3 days)0.50.70.9-1.00.8-0.9-0.9-0.9-0.4-1.0-0.50.8
Intermittent access total infusions0.91.11.6-1.21.2-1.3-1.1-1.1-0.8-1.2-0.80.5
Intermittent access day 1 locomotion1.41.84.5-1.31.0-1.4-1.2-1.2-1.2-2.1-0.51.6
Intermittent access day 15 total locomotion0.71.22.5-1.31.0-1.6-1.1-1.1-0.4-1.6-0.40.7
Intermittent access total locomotion0.60.71.9-1.00.5-1.1-0.6-0.5-0.3-1.40.01.3
Intermittent access standard deviation0.10.20.50.5-0.50.40.40.50.7-0.00.50.2
Left kidney weight0.00.10.20.4-0.20.20.1-0.00.40.1-0.20.4
Right kidney weight0.31.52.51.2-1.31.21.21.11.11.21.01.6
Cocaine induced anxiety0.30.41.0-0.80.3-0.7-0.4-0.5-1.0-1.0-0.00.4
Post-drug Anxiety0.70.81.40.9-1.00.91.10.90.40.71.20.7
Baseline Anxiety0.50.62.01.1-0.21.00.70.40.71.4-0.0-0.6
Tail length1.56.08.72.9-2.42.82.62.42.42.02.41.7
Length with tail2.611.313.73.7-3.63.63.53.43.53.23.32.1
Length without tail1.34.25.62.0-2.32.02.02.02.42.02.21.5
Times rat made contact with spout3.43.95.4-2.32.0-2.2-2.2-2.2-0.7-1.8-1.8-2.1
Lifetime Intake0.91.11.4-1.21.1-1.1-1.0-1.0-1.1-1.1-0.90.5
Liver weight, left1.22.02.51.5-1.51.61.41.41.61.41.31.1
Liver weight, right5.39.311.83.1-3.43.13.33.23.02.33.22.6
Locomotor activity0.10.20.40.50.00.30.20.2-0.60.6-0.4-0.4
Locomotor testing distance0.50.82.2-0.41.0-0.5-0.8-0.8-1.5-0.2-1.2-1.1
Locomotor testing rearing0.20.51.3-0.40.6-0.6-0.7-0.7-1.2-0.7-0.50.3
Locomotion in novel chamber0.30.30.70.1-0.60.10.80.80.2-0.60.60.7
Locomotion in novel chamber post-restriction3.86.29.42.6-2.72.53.13.01.82.42.51.1
Fecal boli incidents, locomotor time 10.20.31.60.30.10.10.20.20.10.7-0.1-1.3
Change in fecal boli incidents, locomotor task3.13.14.41.7-2.11.91.61.51.51.32.11.9
Time >=10cm from walls, locomotor time 13.53.79.72.3-1.82.22.01.90.53.11.40.4
Bouts of movement, locomotor time 10.50.61.7-0.90.8-0.9-0.8-0.7-1.3-0.2-0.40.1
Total resting periods, locomotor time 10.60.72.0-0.80.9-0.7-0.8-0.8-1.4-0.1-0.6-0.5
Rest time, locomotor task time 10.30.41.20.6-0.20.90.40.3-0.51.10.1-0.8
Distance moved, locomotor task time 10.20.31.20.3-0.5-0.10.30.40.5-0.20.31.1
Vertical activity count, locomotor time 10.10.20.70.3-0.5-0.10.30.30.80.10.30.8
Time >=10cm from walls, locomotor time 20.81.21.71.2-1.31.01.21.31.20.71.30.5
Bouts of movement, locomotor time 21.21.93.91.5-1.51.61.41.40.82.01.30.6
Total resting periods, locomotor time 20.91.62.81.3-1.41.41.31.20.71.71.31.0
Rest time, locomotor task time 20.60.81.5-0.90.9-0.7-0.9-1.0-1.2-1.1-0.6-0.2
Distance moved, locomotor task time 20.20.31.00.3-0.6-0.00.30.50.7-0.20.41.0
Vertical activity count, locomotor time 20.10.21.20.3-0.3-0.20.00.11.1-0.3-0.1-0.5
Light reinforcement 12.56.19.6-2.52.6-3.1-2.7-2.5-2.5-3.0-1.8-0.1
Light reinforcement 21.11.73.1-1.31.3-1.7-1.4-1.3-1.4-1.2-1.40.0
Bone: marrow area0.40.81.0-1.01.0-0.7-1.0-1.0-1.0-0.6-0.9-0.7
Bone: maximum diameter0.91.62.2-1.41.4-1.5-1.4-1.4-0.9-1.3-1.2-0.5
Bone: maximum force0.10.10.3-0.20.4-0.2-0.2-0.2-0.50.2-0.6-0.4
Bone: maximum moment0.10.10.4-0.20.4-0.1-0.2-0.2-0.70.3-0.6-0.3
Mean time between licks in bursts0.30.61.70.6-0.81.00.80.80.61.30.50.3
Mean num. licks in bursts3.04.67.3-2.72.0-2.2-2.1-2.1-0.5-2.3-2.1-2.7
Cd content in liver0.30.30.8-0.90.4-0.7-0.5-0.4-0.40.2-0.4-0.8
Co content in liver1.31.53.1-0.81.3-1.0-1.0-1.0-1.70.5-1.4-1.8
Cu content in liver0.10.10.2-0.40.3-0.2-0.3-0.4-0.40.2-0.2-0.4
Fe content in liver0.60.82.0-0.61.0-0.6-0.8-0.9-0.7-0.7-1.0-1.4
K content in liver0.30.30.5-0.70.6-0.7-0.5-0.6-0.5-0.6-0.20.3
Mg content in liver3.33.45.2-2.12.0-2.1-1.9-1.9-1.8-2.3-1.4-0.5
Mn content in liver1.92.13.5-1.91.5-1.6-1.6-1.5-0.9-1.7-1.3-1.0
Na content in liver0.40.50.8-0.80.6-0.9-0.8-0.70.4-0.9-0.40.3
Rb content in liver1.82.12.8-1.51.6-1.7-1.6-1.5-1.3-1.6-1.2-1.1
Se content in liver0.10.10.9-0.0-0.30.30.20.1-0.2-0.30.20.9
Sr content in liver0.90.81.80.8-0.90.70.70.80.90.71.01.4
Zn content in liver0.60.61.50.7-0.70.70.80.70.50.51.01.2
Bone: minimum diameter0.30.50.9-0.60.7-0.3-0.8-0.9-0.5-0.4-0.9-0.9
Time in familiar zone, hab. session 10.10.10.3-0.10.4-0.1-0.3-0.2-0.3-0.4-0.2-0.5
Time in novel zone, hab. session 11.41.42.01.4-1.31.31.31.20.50.91.21.1
Total zone transitions, hab. session 10.10.10.20.3-0.30.30.30.40.3-0.00.4-0.3
Total locomotion distance, hab. session 10.10.20.30.5-0.50.50.50.50.4-0.20.50.1
Locomotion velocity, hab. session 10.10.10.1-0.0-0.30.10.20.30.3-0.30.40.4
Time in familiar zone, hab. session 22.52.63.6-1.61.9-1.5-1.7-1.6-1.3-1.5-1.9-1.6
Time in novel zone, hab. session 22.62.63.91.6-1.91.61.71.61.21.22.01.6
Total zone transitions, hab. session 20.91.22.4-1.01.0-0.8-1.0-1.0-1.1-0.8-1.2-1.6
Total locomotion distance, hab. session 20.10.10.4-0.30.2-0.2-0.3-0.4-0.4-0.6-0.3-0.3
Locomotion velocity, hab. session 20.20.20.4-0.40.4-0.3-0.4-0.5-0.6-0.6-0.5-0.4
Novel to familiar place preference ratio2.52.83.91.5-1.91.51.82.01.51.41.91.2
Novelty place preference2.83.04.31.6-1.91.61.92.11.61.52.01.3
Time in novel zone, NPP test2.72.94.21.6-1.91.61.92.11.41.51.91.1
Total zone transitions, NPP test0.71.01.6-1.01.0-1.0-1.0-1.0-1.3-1.0-0.8-0.5
Total locomotion distance, NPP test0.20.30.7-0.70.4-0.6-0.5-0.5-0.8-0.8-0.2-0.1
Locomotion velocity, NPP test0.71.01.5-1.21.0-1.2-1.0-1.0-1.0-1.2-0.8-0.4
Intraocular pressure0.70.92.70.9-0.91.01.11.2-0.51.60.6-0.2
Delta distance traveled before/after self-admin0.30.31.50.5-0.30.10.50.51.20.10.20.6
Delta ambulatory time before/after self-admin0.30.30.6-0.50.7-0.7-0.7-0.60.3-0.4-0.80.1
Parametrial fat weight1.33.04.72.0-2.02.21.91.81.41.41.51.4
Pavlov. Cond. lever latency1.62.02.91.7-1.51.41.51.51.21.01.41.2
Pavlov. Cond. magazine entry latency0.10.10.6-0.70.1-0.5-0.3-0.20.2-0.40.20.4
Pavlov. Cond. change in total contacts0.10.10.4-0.5-0.0-0.3-0.2-0.1-0.2-0.20.20.6
Pavlov. Cond. index score0.40.51.3-1.20.7-0.8-0.8-0.8-0.3-0.6-0.5-0.3
Pavlov. Cond. latency score0.30.41.2-1.10.6-0.7-0.7-0.7-0.3-0.5-0.5-0.3
Pavlov. Cond. lever contacts1.21.42.5-1.61.2-1.3-1.4-1.3-0.9-0.9-1.1-0.8
Pavlov. Cond. magazine entry number0.20.20.80.9-0.40.60.50.4-0.00.50.2-0.0
Pavlov. Cond. intertrial magazine entries0.81.02.9-0.60.9-0.5-0.7-0.8-1.3-0.4-1.3-1.7
Pavlov. Cond. lever-magazine prob. diff.0.70.81.9-1.40.9-1.1-1.0-1.0-0.5-0.7-0.7-0.5
Pavlov. Cond. response bias1.01.22.3-1.51.1-1.2-1.2-1.2-0.6-0.9-1.1-0.9
Pavlov. Cond. lever latency0.10.10.40.4-0.20.30.30.30.7-0.00.20.1
Pavlov. Cond. magazine entry latency0.40.51.0-0.80.7-0.7-0.7-0.7-1.0-0.6-0.60.0
Pavlov. Cond. change in total contacts0.00.10.3-0.1-0.2-0.10.00.1-0.50.40.10.3
Pavlov. Cond. index score0.20.30.7-0.60.4-0.6-0.5-0.5-0.8-0.3-0.5-0.1
Pavlov. Cond. latency score0.10.20.4-0.50.3-0.5-0.4-0.4-0.6-0.3-0.30.1
Pavlov. Cond. lever contacts0.00.10.3-0.30.1-0.2-0.2-0.2-0.60.1-0.1-0.1
Pavlov. Cond. magazine entry number0.30.40.80.9-0.50.80.60.50.70.50.4-0.3
Pavlov. Cond. intertrial magazine entries1.82.84.12.0-1.81.81.71.82.01.21.50.7
Pavlov. Cond. lever-magazine prob. diff.0.10.20.6-0.50.4-0.5-0.4-0.4-0.8-0.2-0.4-0.2
Pavlov. Cond. response bias0.40.51.3-0.90.6-0.8-0.7-0.7-1.1-0.4-0.6-0.1
Time in closed arm before self-admin1.92.47.01.2-1.51.01.11.21.90.81.62.7
Time in closed arm after self-admin3.53.76.31.5-2.01.31.81.92.51.42.32.3
Time in open arm before self-admin0.70.74.70.30.20.40.30.2-0.80.7-0.6-2.2
Time in open arm after self-admin1.51.64.7-0.91.4-0.9-1.0-1.1-2.2-1.1-1.3-1.0
Bone: periosteal estimation0.51.01.4-1.11.1-1.0-1.2-1.2-0.9-0.7-1.0-0.6
Bone: periosteal perimeter0.10.20.4-0.50.4-0.5-0.6-0.60.2-0.2-0.4-0.2
Bone: post-yield work0.10.10.30.20.30.20.20.0-0.6-0.10.20.4
Progressive ratio test 1 active lever presses0.91.22.2-1.31.0-1.2-0.9-0.9-1.1-1.5-0.71.1
Progressive ratio test 1 breakpoint1.21.52.7-1.41.1-1.4-1.1-1.0-1.3-1.6-0.81.0
Progressive ratio test 1 inactive lever presses0.91.23.8-1.41.0-1.3-1.1-0.8-0.9-1.9-0.30.3
Progressive ratio test 2 active lever presses0.20.20.7-0.60.4-0.6-0.3-0.30.0-0.7-0.10.8
Progressive ratio test 2 breakpoint0.20.30.7-0.60.4-0.6-0.4-0.3-0.0-0.7-0.20.8
Progressive ratio test 2 inactive lever presses0.10.20.6-0.40.6-0.3-0.4-0.4-0.3-0.7-0.5-0.4
Incentive Sensitization - Responses0.10.10.70.2-0.20.10.30.30.30.30.30.8
Incentive Sensitization - Breakpoint0.20.20.90.3-0.30.20.40.40.50.30.41.0
Sum of active levers in priming session hrs 5-60.40.41.3-0.30.8-0.2-0.5-0.6-0.2-0.0-0.9-1.1
Progressive ratio0.20.21.7-0.00.1-0.2-0.3-0.0-0.0-1.30.1-0.6
Food seeking constrained by brief footshock1.01.33.3-0.91.3-0.9-0.9-0.9-0.8-0.6-1.5-1.8
Seeking ratio, punishment vs. effort0.30.42.70.20.00.30.40.20.11.7-0.3-0.4
Retroperitoneal fat weight6.628.137.35.6-6.15.55.65.65.13.85.44.7
Reaction time number correct0.10.10.30.4-0.30.20.30.30.50.40.1-0.2
Reaction time mean minus median0.10.30.7-0.60.6-0.3-0.3-0.3-0.5-0.8-0.5-0.7
Reaction time mean minus median AUC0.10.40.80.4-0.40.90.90.80.30.70.3-0.0
Reaction time num false alarms0.30.42.40.6-0.20.30.30.3-0.81.50.2-0.2
Reaction time num false alarms AUC0.20.31.70.5-0.10.10.20.1-1.01.30.1-0.1
Reaction time trials correct on left0.10.10.30.4-0.30.20.30.30.50.40.1-0.2
Reaction time trials on left0.10.10.20.4-0.40.20.30.40.50.50.1-0.1
Reaction time mean0.40.61.20.9-0.61.01.11.00.10.70.70.4
Reaction time mean AUC0.50.91.61.1-0.81.11.21.10.30.90.90.5
Median of all reaction times0.71.01.81.2-0.81.21.31.20.21.10.90.6
Reaction time omissions0.30.41.00.9-0.50.80.90.7-0.21.00.3-0.3
Reaction time false alarm rate0.20.21.20.20.1-0.10.0-0.1-1.10.80.20.3
Reaction time premature initiation rate0.50.71.4-1.20.8-1.0-1.1-1.1-0.1-0.9-0.5-0.1
Reaction time premature initiations0.10.30.5-0.70.4-0.6-0.7-0.60.2-0.4-0.4-0.3
Std. dev. reaction times0.10.10.30.4-0.10.50.60.50.10.00.3-0.2
Reaction time trials completed0.10.10.20.4-0.40.20.30.40.50.50.1-0.1
Reaction time trials AUC0.00.00.10.2-0.10.00.10.10.30.2-0.1-0.2
Run reversals in cocaine runway, females0.50.52.0-0.1-0.70.00.20.31.4-0.20.71.3
Run reversals in cocaine runway, males0.20.20.60.0-0.30.30.20.40.50.40.40.8
Latency to leave start box in cocaine runway1.21.42.0-1.11.2-1.2-1.3-1.4-0.8-1.2-1.3-1.1
Latency to leave start box in cocaine runway, F1.82.12.7-1.41.5-1.4-1.5-1.5-1.3-1.2-1.5-1.6
Latency to leave start box in cocaine runway, M0.10.10.40.3-0.30.10.1-0.10.6-0.00.20.4
Std. dev. time between licks in bursts0.40.61.10.9-0.90.90.60.60.51.00.80.2
Total sessions with >9 infusions0.20.31.3-0.40.3-0.4-0.2-0.0-0.7-1.10.00.6
Short access day 1 total inactive lever presses0.60.82.4-0.90.9-0.7-0.8-0.9-0.6-1.5-0.40.9
Short access day 10 total inactive lever presses0.30.82.3-0.40.9-0.6-0.5-0.4-0.8-1.5-0.5-1.4
Short access day 1 total infusions0.30.41.5-0.40.5-0.4-0.4-0.4-1.1-0.7-0.31.2
Short access day 10 total infusions3.44.46.7-2.61.9-2.2-2.4-2.1-2.1-2.5-1.8-0.4
Short access total infusions0.81.01.6-1.10.9-0.7-1.1-1.0-1.3-1.2-1.00.4
Short access day 1 locomotion0.60.83.0-0.90.6-0.8-0.6-0.7-0.6-1.7-0.20.9
Short access day 10 total locomotion1.83.49.3-2.11.4-2.0-1.8-1.5-2.0-3.1-1.00.4
Short access total locomotion0.60.73.4-0.80.3-0.6-0.5-0.4-0.4-1.80.11.0
One hour access (0.3 mA shock)0.50.61.2-1.10.7-1.0-0.8-0.7-0.2-0.9-0.60.4
Compulsive drug intake0.50.51.20.6-0.70.80.80.71.10.70.70.4
One hour access (shock baseline)0.60.91.7-1.21.0-1.3-1.0-1.0-0.5-1.0-0.70.0
Social response proportion0.20.20.3-0.50.3-0.4-0.6-0.6-0.4-0.3-0.40.2
Social responses0.30.31.60.1-0.30.1-0.1-0.20.6-0.80.61.3
Social time0.50.72.1-0.80.8-0.5-1.0-1.0-0.3-1.4-0.8-0.5
Soleus weight2.47.09.0-2.92.8-3.0-3.0-2.9-2.9-2.5-2.1-1.1
Bone: stiffness0.30.41.00.7-0.60.80.70.70.21.00.40.4
Tibialis anterior weight2.99.814.6-3.43.0-3.6-3.4-3.3-3.8-3.4-2.5-0.6
Time to tail flick, vehicle, before self-admin1.92.04.01.8-1.42.01.21.31.21.90.80.0
Time to tail flick, vehicle, after self-admin0.50.61.40.9-0.80.80.70.71.2-0.31.0-0.1
Time to tail flick, test, before self-admin0.90.91.81.1-1.00.91.21.30.50.51.20.1
Time to tail flick, test, after self-admin0.40.41.50.4-0.50.60.30.20.2-0.30.91.2
Delta time to tail flick, vehicle, before/after SA0.60.61.6-0.70.8-0.9-0.7-0.7-0.6-1.3-0.5-0.7
Delta time to tail flick, test, before/after SA2.02.03.6-1.41.5-1.2-1.8-1.9-1.2-1.6-1.3-0.2
Tibia length1.64.57.31.9-2.22.12.01.92.61.12.32.7
Ambulatory time before self-admin1.01.42.31.1-1.30.91.41.30.70.91.51.4
Ambulatory time after self-admin0.50.62.10.7-0.60.40.30.31.40.50.61.1
Bone: tissue strength0.30.30.60.6-0.50.70.70.7-0.00.80.40.2
Total heroin consumption1.31.52.3-1.21.5-1.5-1.1-1.0-1.4-1.5-1.2-0.5
Bone: trabecular number4.47.39.6-2.52.9-2.7-2.8-2.7-2.6-2.3-3.1-2.8
Bone: trabecular spacing2.53.34.41.6-1.82.11.91.81.72.11.81.5
Bone: trabecular thickness0.81.01.5-1.01.0-1.2-1.1-1.1-1.0-1.1-1.0-0.2
Bone: trabecular tissue density0.00.00.1-0.20.2-0.3-0.00.00.3-0.4-0.0-0.0
Water consumed over 24 hours0.60.81.0-0.70.9-0.9-1.0-1.0-0.5-1.0-0.6-1.0
Number of responses in last shaping day0.60.71.01.0-1.00.90.70.90.80.81.00.3