Hub : Genes

ENSRNOG00000070264

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	ENSRNOG00000070264	0.02	0.02	4.7e-03	0	0.01	0	0	1.3e-01	4.7e-02	2.0e-01	2.1e-01
2	Liver	intron excision ratio	chr7:10167304:10167452	0.02	0.02	6.4e-03	0.01	0.02	0.02	0.01	1.1e-02	5.4e-03	3.7e-03	6.7e-03
3	Liver	intron excision ratio	chr7:10167304:10167763	0.02	0.02	1.4e-03	0.01	0.02	0.02	0.01	2.9e-02	3.0e-03	4.9e-03	8.6e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	6.6	21.5	23.0	-4.8	-4.4	4.7
BMI without tail	2.7	5.6	8.1	-2.2	-2.8	2.0
Body weight	1.2	5.0	5.4	-2.2	-2.3	2.2
Epididymis fat weight	0.3	0.6	0.6	0.8	0.8	-0.8
Glucose	1.6	2.4	2.9	-1.7	-1.2	1.7
Heart weight	0.2	0.2	0.6	0.3	0.7	-0.3
Left kidney weight	0.0	0.0	0.1	0.2	0.2	-0.1
Right kidney weight	1.2	3.3	3.6	1.9	1.6	-1.9
Tail length	3.0	9.1	11.2	3.3	2.2	-3.3
Length with tail	1.9	6.8	7.6	2.8	2.3	-2.7
Length without tail	0.1	0.2	0.5	0.4	0.7	-0.3
Liver weight, left	2.1	3.3	3.4	-1.8	-1.8	1.8
Liver weight, right	1.4	2.3	2.4	-1.5	-1.5	1.5
Parametrial fat weight	0.3	0.7	0.9	0.9	0.6	-0.9
Retroperitoneal fat weight	0.2	0.7	0.7	-0.8	-0.9	0.8
Intraocular pressure	0.0	0.0	0.0	-0.2	-0.2	0.1
Extensor digitorum longus weight	4.7	18.9	24.7	-4.1	-5.0	3.9
Soleus weight	9.2	26.7	28.3	-5.3	-4.9	5.3
Tibialis anterior weight	1.1	3.7	5.1	-1.8	-2.3	1.7
Tibia length	0.8	2.2	2.7	1.6	1.1	-1.6
Number of licking bursts	0.1	0.2	0.4	-0.2	-0.7	0.1
Food consumed during 24 hour testing period	0.7	0.8	1.0	-0.9	-1.0	0.8
Times rat made contact with spout	0.3	0.4	0.8	-0.5	-0.9	0.4
Mean time between licks in bursts	4.0	5.5	6.2	2.5	2.1	-2.5
Mean num. licks in bursts	0.0	0.0	0.0	-0.2	-0.0	0.2
Std. dev. time between licks in bursts	0.6	0.8	0.9	0.9	0.8	-0.9
Water consumed over 24 hours	0.6	0.7	0.8	-0.8	-0.9	0.9
Indifference point 0 sec	0.2	0.3	0.4	-0.6	-0.3	0.6
Indifference point AUC	0.7	0.8	0.8	0.9	0.9	-0.9
Indifference point function ln k	0.3	0.4	0.6	-0.6	-0.8	0.5
Indifference point function log k	0.3	0.4	0.6	-0.6	-0.8	0.5
Delay discounting total patch changes 0 sec	0.1	0.2	0.2	-0.5	-0.4	0.5
Delay discounting total patch changes 12 sec	0.5	0.6	0.8	-0.7	-0.9	0.7
Delay discounting total patch changes 18 sec	1.0	1.3	1.3	1.2	1.2	-1.1
Delay discounting total patch changes 24 sec	0.1	0.1	0.2	0.1	0.5	-0.1
Delay discounting total patch changes 6 sec	0.1	0.2	0.5	0.2	0.7	-0.2
Delay discounting time to switch 0 sec	0.6	0.9	1.3	-1.0	-0.5	1.1
Delay discounting water rate 0 sec	0.2	0.4	1.1	-0.0	-1.1	-0.1
Delay discounting water rate 12 sec	1.4	2.1	3.2	-1.3	-1.8	1.2
Delay discounting water rate 18 sec	0.3	0.4	1.1	0.1	-1.1	-0.3
Delay discounting water rate 24 sec	0.9	1.2	3.0	-0.7	-1.7	0.4
Delay discounting water rate 6 sec	0.2	0.3	0.4	0.5	-0.4	-0.6
Locomotor activity	2.9	4.6	5.0	2.2	2.1	-2.1
Locomotor testing distance	1.7	2.8	3.2	1.6	1.8	-1.6
Locomotor testing rearing	0.0	0.0	0.1	0.1	-0.3	-0.2
Light reinforcement 1	6.7	12.3	12.7	3.5	3.6	-3.4
Light reinforcement 2	2.3	3.0	3.6	1.7	1.9	-1.6
Reaction time number correct	0.8	1.1	2.2	-0.8	-1.5	0.6
Reaction time mean minus median	0.5	0.7	0.8	0.9	0.7	-0.9
Reaction time mean minus median AUC	0.0	0.0	0.1	0.1	0.3	-0.1
Reaction time num false alarms	0.4	0.5	1.5	-0.3	-1.2	0.2
Reaction time num false alarms AUC	0.5	0.7	1.9	-0.4	-1.4	0.2
Reaction time trials correct on left	0.8	1.1	2.2	-0.8	-1.5	0.6
Reaction time trials on left	0.8	1.1	2.1	-0.8	-1.5	0.7
Reaction time mean	0.0	0.1	0.1	-0.3	0.0	0.3
Reaction time mean AUC	0.1	0.1	0.2	-0.4	0.0	0.4
Median of all reaction times	0.3	0.4	0.6	-0.8	-0.3	0.8
Reaction time omissions	0.3	0.4	1.1	0.3	1.0	-0.2
Reaction time false alarm rate	0.1	0.1	0.3	-0.1	-0.6	0.1
Reaction time premature initiation rate	0.8	1.1	1.1	1.0	1.0	-1.1
Reaction time premature initiations	0.3	0.4	0.7	0.7	0.3	-0.8
Std. dev. reaction times	0.1	0.1	0.1	0.3	0.3	-0.4
Reaction time trials completed	0.8	1.1	2.1	-0.8	-1.5	0.7
Reaction time trials AUC	0.8	1.1	2.4	-0.8	-1.5	0.6
Social response proportion	0.8	0.9	1.5	0.8	1.2	-0.7
Social responses	6.7	8.6	9.1	3.0	2.9	-2.9
Social time	0.5	0.7	1.0	-1.0	-0.3	1.0
Conditioned locomotion	1.7	2.0	3.0	-1.3	-1.7	1.2
Cocaine response after cond. corrected	6.2	7.0	7.9	-2.6	-2.8	2.5
Cocaine response after cond. not corrected	6.5	7.2	8.5	-2.6	-2.9	2.5
Cocaine response before conditioning	0.6	0.7	0.9	1.0	0.5	-1.0
Saline control response	0.0	0.1	0.1	-0.3	-0.2	0.2
Condit. Reinf. active minus inactive responses	1.4	1.8	2.2	1.4	1.1	-1.5
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.1	-0.3	0.2	0.2
Condit. Reinf. active responses	1.5	2.0	2.5	1.5	1.1	-1.6
Condit. Reinf. inactive responses	1.1	1.4	2.0	1.4	0.5	-1.4
Condit. Reinf. lever presses	1.8	2.5	2.9	1.6	1.3	-1.7
Condit. Reinf. lever reinforcers received	0.9	1.3	1.8	1.3	0.8	-1.3
Pavlov. Cond. lever latency	0.4	0.6	0.7	-0.8	-0.6	0.8
Pavlov. Cond. magazine entry latency	0.4	0.5	0.7	0.8	0.4	-0.8
Pavlov. Cond. change in total contacts	0.3	0.5	0.5	0.7	0.7	-0.7
Pavlov. Cond. index score	0.5	0.7	0.9	0.9	0.6	-0.9
Pavlov. Cond. latency score	0.5	0.6	0.7	0.8	0.7	-0.8
Pavlov. Cond. lever contacts	0.4	0.5	0.7	0.8	0.5	-0.8
Pavlov. Cond. magazine entry number	0.7	0.8	1.1	-1.0	-0.5	1.1
Pavlov. Cond. intertrial magazine entries	0.4	0.5	0.8	-0.6	-0.9	0.5
Pavlov. Cond. lever-magazine prob. diff.	0.6	0.7	0.9	0.9	0.6	-1.0
Pavlov. Cond. response bias	1.2	1.6	2.1	1.4	1.0	-1.4
Conditioned reinforcement - actives	2.0	2.0	2.0	1.4	1.4	-1.4
Conditioned reinforcement - inactives	0.3	0.4	0.5	-0.6	-0.7	0.5
Conditioned locomotion	7.1	8.5	9.1	3.0	2.8	-3.0
Intermittent access intake day 1-15 change	5.8	5.7	6.5	2.5	2.0	-2.5
Intermittent access intake escalation	4.9	4.8	6.1	2.4	1.6	-2.5
Intermittent access intake escalation 2	5.9	5.8	7.0	2.6	2.0	-2.6
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.1	0.3	-0.1	-0.3
Intermitt. access day 15 inactive lever presses	0.5	0.6	0.7	0.8	0.5	-0.9
Intermitt. access escalation Index	0.1	0.1	0.2	-0.4	-0.1	0.4
Intermittent access day 1 total infusions	0.0	0.0	0.0	-0.1	0.1	0.1
Intermittent access day 15 total infusions	1.9	2.1	2.5	1.6	1.2	-1.6
Intermittent access terminal intake (last 3 days)	1.0	1.1	1.3	1.1	0.9	-1.1
Intermittent access total infusions	0.2	0.3	0.3	0.6	0.4	-0.6
Intermittent access day 1 locomotion	0.5	0.5	0.6	0.8	0.6	-0.8
Intermittent access day 15 total locomotion	3.9	4.2	4.6	2.1	1.8	-2.1
Intermittent access total locomotion	1.1	1.3	1.3	1.1	1.1	-1.1
Intermittent access standard deviation	2.2	2.4	3.0	1.7	1.2	-1.7
Cocaine induced anxiety	0.6	0.7	1.3	0.7	1.1	-0.6
Post-drug Anxiety	0.7	0.8	1.3	0.8	1.1	-0.7
Baseline Anxiety	0.2	0.2	0.3	0.5	0.0	-0.6
Lifetime Intake	0.1	0.1	0.1	0.4	0.3	-0.4
Incentive Sensitization - Responses	0.0	0.0	0.0	0.1	0.0	-0.1
Incentive Sensitization - Breakpoint	0.0	0.0	0.1	0.2	0.2	-0.2
Progressive ratio test 1 active lever presses	0.1	0.1	0.2	-0.0	-0.4	-0.1
Progressive ratio test 1 breakpoint	0.1	0.1	0.3	-0.1	-0.6	0.0
Progressive ratio test 1 inactive lever presses	0.1	0.1	0.1	0.3	0.3	-0.3
Progressive ratio test 2 active lever presses	0.1	0.1	0.1	0.3	0.1	-0.4
Progressive ratio test 2 breakpoint	0.2	0.2	0.2	0.4	0.4	-0.4
Progressive ratio test 2 inactive lever presses	0.1	0.1	0.2	0.2	0.4	-0.2
Total sessions with >9 infusions	0.0	0.0	0.0	-0.1	0.0	0.2
Short access day 1 total inactive lever presses	0.2	0.2	0.2	0.4	0.5	-0.4
Short access day 10 total inactive lever presses	0.0	0.0	0.0	-0.0	-0.1	0.0
Short access day 1 total infusions	0.3	0.4	0.7	0.5	0.8	-0.4
Short access day 10 total infusions	0.1	0.1	0.2	0.4	-0.0	-0.4
Short access total infusions	0.0	0.0	0.0	0.1	0.1	-0.0
Short access day 1 locomotion	1.1	1.2	1.4	1.1	1.2	-1.0
Short access day 10 total locomotion	3.4	3.7	4.4	2.1	1.5	-2.1
Short access total locomotion	0.9	0.9	1.0	1.0	0.9	-1.0
Compulsive drug intake	1.3	1.3	1.6	-1.2	-0.8	1.3
One hour access (0.3 mA shock)	0.1	0.1	0.1	-0.3	-0.4	0.2
One hour access (shock baseline)	0.1	0.2	0.3	0.5	-0.0	-0.5
Number of responses in last shaping day	0.1	0.1	0.2	0.4	0.4	-0.4
Context. condit. distance diff. score	0.2	0.3	0.9	-0.2	-0.9	0.1
Locomotion velocity, session 1	0.7	0.7	1.6	0.6	1.2	-0.5
Locomotion distance, session 1	0.4	0.5	0.7	0.7	0.8	-0.5
Locomotion velocity, session 2	4.9	5.8	6.4	2.5	2.3	-2.4
Locomotion distance, session 2	2.0	2.9	5.5	1.3	2.3	-1.1
Locomotion velocity, session 3	6.7	7.8	9.6	3.1	2.1	-3.1
Locomotion distance, session 3	0.0	0.1	0.1	0.2	-0.3	-0.2
Stereotopy head waving bouts, day 3	6.1	7.3	8.3	2.9	2.4	-2.8
Stereotopy head waving duration, day 3	6.8	8.2	9.2	3.0	2.5	-3.0
Locomotion velocity, session 7	0.9	1.0	1.5	1.2	-0.2	-1.2
Locomotion distance, session 7	0.4	0.5	1.3	-0.3	-1.2	0.2
Stereotopy head waving bouts, day 7	0.1	0.1	0.2	0.3	0.5	-0.2
Stereotopy head waving duration, day 7	0.4	0.5	0.9	0.6	0.9	-0.5
Locomotion velocity, session 8	0.9	1.1	1.4	1.2	0.9	-1.1
Locomotion distance, session 8	0.3	0.5	0.6	0.8	0.5	-0.7
Degree of sensitization distance	0.4	0.4	0.8	-0.5	-0.9	0.5
Degree of sensitization stereotypy	1.6	1.7	2.3	-1.5	-0.9	1.5
Condit. Reinf. active minus inactive responses	5.2	5.8	6.4	2.5	2.1	-2.5
Condit. Reinf. active-inactive response ratio	2.0	2.2	2.4	1.5	1.4	-1.5
Condit. Reinf. active responses	4.6	5.6	5.9	2.4	2.3	-2.3
Condit. Reinf. inactive responses	1.2	1.4	1.9	1.1	1.4	-1.0
Incentive salience index mean	3.1	3.8	4.2	2.0	1.8	-2.0
Condit. Reinf. lever presses	0.2	0.2	0.7	0.2	0.8	-0.0
Time in familiar zone, hab. session 1	2.0	1.9	2.3	1.5	1.1	-1.5
Time in novel zone, hab. session 1	1.0	1.0	1.3	-1.1	-0.6	1.2
Total zone transitions, hab. session 1	1.3	1.8	2.5	1.3	1.6	-1.1
Total locomotion distance, hab. session 1	1.5	2.2	2.4	1.5	1.5	-1.4
Locomotion velocity, hab. session 1	2.1	3.0	3.4	1.9	1.7	-1.7
Time in familiar zone, hab. session 2	5.9	6.1	6.8	2.5	2.3	-2.6
Time in novel zone, hab. session 2	4.5	4.6	5.3	-2.3	-1.8	2.3
Total zone transitions, hab. session 2	0.2	0.2	0.4	-0.2	0.7	0.4
Total locomotion distance, hab. session 2	1.5	2.0	3.1	1.3	1.8	-1.1
Locomotion velocity, hab. session 2	1.6	2.1	3.5	1.3	1.9	-1.1
Novel to familiar place preference ratio	3.9	4.0	5.3	-2.2	-1.4	2.3
Novelty place preference	2.3	2.4	3.2	-1.7	-1.0	1.8
Time in novel zone, NPP test	2.6	2.7	3.5	-1.8	-1.2	1.9
Total zone transitions, NPP test	0.2	0.3	0.8	0.0	0.9	0.1
Total locomotion distance, NPP test	0.1	0.1	0.3	0.2	0.5	-0.0
Locomotion velocity, NPP test	0.2	0.3	0.7	0.4	0.9	-0.2
Pavlov. Cond. lever latency	0.1	0.1	0.2	-0.5	0.1	0.4
Pavlov. Cond. magazine entry latency	4.0	5.1	6.4	2.5	1.6	-2.5
Pavlov. Cond. change in total contacts	0.4	0.4	0.6	0.8	-0.1	-0.8
Pavlov. Cond. index score	1.0	1.3	1.9	1.4	0.5	-1.3
Pavlov. Cond. latency score	1.0	1.3	1.8	1.4	0.6	-1.3
Pavlov. Cond. lever contacts	0.2	0.3	0.4	0.7	0.2	-0.5
Pavlov. Cond. magazine entry number	1.3	1.6	2.1	-1.5	-0.8	1.4
Pavlov. Cond. intertrial magazine entries	0.0	0.0	0.1	0.2	0.0	-0.3
Pavlov. Cond. lever-magazine prob. diff.	1.5	1.8	2.6	1.6	0.8	-1.5
Pavlov. Cond. response bias	1.8	2.2	3.0	1.7	0.9	-1.7
Bone: apparent density	0.3	0.4	0.7	-0.4	0.8	0.6
Bone surface	0.6	1.0	2.9	0.2	1.7	0.1
Bone volume	0.5	0.8	2.4	0.1	1.5	0.2
Bone: connectivity density	0.3	0.4	0.7	-0.7	0.3	0.9
Bone: cortical apparent density	1.1	1.4	1.9	-1.4	-0.6	1.4
Bone: cortical area	0.5	0.7	0.9	-0.9	-0.7	1.0
Bone: cortical porosity	0.5	0.5	0.8	0.7	0.9	-0.6
Bone: cortical porosity	0.1	0.1	0.3	0.1	0.5	-0.0
Bone: cortical thickness	1.1	1.9	2.3	-1.5	-1.1	1.5
Bone: cortical thickness	0.1	0.1	0.3	-0.2	-0.5	0.1
Bone: cortical tissue density	0.8	1.0	1.4	-1.2	-0.5	1.2
Bone: elastic displacement	0.2	0.2	0.5	0.1	0.7	-0.1
Bone: elastic work	0.4	0.5	0.7	-0.8	-0.3	0.8
Bone: endosteal estimation	0.1	0.3	0.5	-0.4	-0.7	0.4
Bone: endosteal perimeter	0.3	0.6	0.7	0.9	0.7	-0.8
Bone: final force	1.3	2.1	2.4	-1.4	-1.5	1.4
Bone: final moment	1.0	1.7	1.7	-1.3	-1.3	1.3
Bone: marrow area	0.1	0.3	0.5	-0.4	-0.7	0.4
Bone: maximum diameter	0.7	1.4	1.5	1.2	1.2	-1.1
Bone: maximum force	1.3	2.2	2.7	-1.4	-1.6	1.4
Bone: maximum moment	1.0	1.8	2.0	-1.3	-1.4	1.3
Bone: minimum diameter	0.0	0.1	0.1	0.2	-0.3	-0.2
Bone: periosteal estimation	0.2	0.4	0.5	-0.6	-0.6	0.7
Bone: periosteal perimeter	0.1	0.1	0.1	0.3	0.3	-0.3
Bone: post-yield work	0.6	0.9	2.2	-0.5	-1.5	0.4
Bone: stiffness	2.7	4.3	5.4	-1.9	-2.3	1.9
Bone: tissue strength	1.8	1.8	2.1	-1.4	-1.0	1.5
Bone: trabecular number	0.7	1.1	1.7	0.9	1.3	-0.8
Bone: trabecular spacing	0.8	1.1	2.6	-0.7	-1.6	0.4
Bone: trabecular thickness	0.6	0.7	1.4	-0.4	1.2	0.7
Bone: trabecular tissue density	1.6	2.2	3.1	-1.4	-1.8	1.3
Breakpoint value in progressive ratio session	5.1	5.7	6.7	2.5	2.0	-2.6
Distance traveled before self-admin	0.7	0.7	1.0	-1.0	-0.6	1.0
Distance traveled after self-admin	0.4	0.5	0.6	0.7	0.7	-0.6
Delta time in closed arm before/after self-admin	1.5	1.5	2.8	-0.9	-1.7	0.8
Delta time in open arm before/after self-admin	1.1	1.1	1.5	-1.2	-0.5	1.2
Diff in mean of infusions in LGA sessions	1.9	2.2	2.4	1.6	1.3	-1.6
Extinction: sum of active levers before priming	1.0	1.1	1.5	1.2	0.5	-1.2
Active lever presses in extinction session 6	2.6	2.5	3.3	1.5	1.8	-1.4
Delta distance traveled before/after self-admin	2.0	2.1	2.5	1.6	1.2	-1.6
Delta ambulatory time before/after self-admin	2.3	2.5	2.8	1.7	1.4	-1.6
Time in closed arm before self-admin	0.5	0.5	0.9	-0.8	-0.2	1.0
Time in closed arm after self-admin	0.0	0.0	0.0	0.0	-0.1	-0.0
Time in open arm before self-admin	0.8	0.8	1.1	1.0	0.6	-1.0
Time in open arm after self-admin	0.8	0.8	1.0	-1.0	-0.7	1.0
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.0	-0.0	0.0	0.0
Time to tail flick, vehicle, before self-admin	0.7	0.8	1.3	0.7	1.1	-0.7
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.2	0.4	-0.0	-0.5
Time to tail flick, test, before self-admin	0.2	0.2	0.3	0.4	0.6	-0.3
Time to tail flick, test, after self-admin	0.3	0.3	0.3	0.6	0.5	-0.5
Delta time to tail flick, vehicle, before/after SA	0.7	0.7	1.6	-0.6	-1.3	0.5
Delta time to tail flick, test, before/after SA	0.2	0.2	0.2	0.4	0.4	-0.5
Ambulatory time before self-admin	0.6	0.7	0.9	-0.9	-0.4	1.0
Ambulatory time after self-admin	0.2	0.2	0.2	0.5	0.4	-0.4
Total heroin consumption	2.0	2.5	2.5	1.6	1.6	-1.5
Area under the delay curve	2.2	2.4	2.5	-1.6	-1.5	1.6
Delay disc. indifference point, 0s delay	6.0	6.6	9.0	-2.8	-1.6	3.0
Delay disc. indifference point, 16s delay	0.1	0.1	0.1	-0.3	-0.2	0.3
Delay disc. indifference point, 2s delay	5.1	5.7	6.3	-2.5	-2.1	2.5
Delay disc. indifference point, 24s delay	0.9	0.9	1.0	-1.0	-0.9	1.0
Delay disc. indifference point, 4s delay	0.7	0.7	0.8	-0.9	-0.8	0.9
Delay disc. indifference point, 8s delay	1.7	1.7	2.6	-1.2	-1.6	1.1
Delay discount exponential model param	2.1	2.2	2.3	1.5	1.5	-1.5
Delay discount hyperbolic model param	2.9	3.1	3.2	1.8	1.7	-1.8
Fecal boli incidents, locomotor time 1	1.8	2.0	2.6	-1.3	-1.6	1.3
Change in fecal boli incidents, locomotor task	0.1	0.1	0.1	0.4	0.1	-0.3
Time >=10cm from walls, locomotor time 1	0.9	0.9	1.4	-1.1	-0.4	1.2
Bouts of movement, locomotor time 1	0.4	0.4	0.6	0.7	-0.3	-0.8
Total resting periods, locomotor time 1	0.4	0.4	0.7	0.8	-0.0	-0.8
Rest time, locomotor task time 1	0.6	0.6	1.0	1.0	0.0	-1.0
Distance moved, locomotor task time 1	0.9	1.0	1.6	-1.2	0.0	1.3
Vertical activity count, locomotor time 1	0.5	0.6	0.9	-0.9	-0.2	0.9
Time >=10cm from walls, locomotor time 2	2.1	2.3	2.8	-1.4	-1.7	1.4
Bouts of movement, locomotor time 2	0.8	0.8	1.5	0.8	1.2	-0.7
Total resting periods, locomotor time 2	0.7	0.7	1.3	0.7	1.2	-0.6
Rest time, locomotor task time 2	0.6	0.7	0.7	0.8	0.8	-0.8
Distance moved, locomotor task time 2	0.8	0.9	1.0	-0.9	-1.0	0.9
Vertical activity count, locomotor time 2	0.9	1.0	1.6	-0.9	-1.3	0.8
Weight adjusted by age	0.7	0.7	1.2	-0.8	-1.1	0.7
Seeking ratio, delayed vs. immediate footshock	4.4	5.1	5.4	2.3	2.1	-2.3
Locomotion in novel chamber	0.0	0.0	0.1	0.2	0.1	-0.3
Locomotion in novel chamber post-restriction	0.9	1.0	1.6	1.2	0.3	-1.3
Progressive ratio	0.1	0.1	0.4	-0.2	-0.6	0.2
Food seeking constrained by brief footshock	0.5	0.6	0.9	1.0	0.4	-0.9
Seeking ratio, punishment vs. effort	0.3	0.4	0.4	0.6	0.6	-0.6
Run reversals in cocaine runway, females	0.5	0.5	0.6	0.8	0.5	-0.7
Run reversals in cocaine runway, males	1.6	1.6	1.8	1.2	1.3	-1.2
Latency to leave start box in cocaine runway	0.8	0.9	2.4	0.4	1.6	-0.2
Latency to leave start box in cocaine runway, F	0.5	0.6	0.7	-0.7	0.8	0.8
Latency to leave start box in cocaine runway, M	2.3	2.2	2.9	1.6	1.0	-1.7
Cd content in liver	0.3	0.3	0.4	-0.6	-0.4	0.6
Co content in liver	0.6	0.7	0.9	0.9	0.4	-1.0
Cu content in liver	0.0	0.0	0.1	-0.2	-0.1	0.3
Fe content in liver	0.2	0.3	0.3	0.6	-0.5	-0.6
K content in liver	0.1	0.1	0.1	0.4	-0.3	-0.3
Mg content in liver	0.0	0.0	0.0	0.1	-0.1	-0.0
Mn content in liver	1.3	1.4	1.8	1.3	1.1	-1.2
Na content in liver	0.5	0.6	1.0	-0.5	-1.0	0.6
Rb content in liver	0.2	0.3	0.5	-0.6	-0.2	0.7
Se content in liver	0.5	0.6	1.0	1.0	-0.0	-1.0
Sr content in liver	0.0	0.0	0.1	0.1	-0.2	-0.2
Zn content in liver	1.2	1.3	1.8	1.2	0.7	-1.3