Hub : Genes

Prkag1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000070180 0.04 0.05 3.0e-03 0 0.01 0.01 0.01 1.1e-01 4.6e-02 5.8e-02 5.2e-02
2 BLA gene expression ENSRNOG00000070180 0.11 0.08 1.5e-06 0.09 0.1 0.05 0.06 1.4e-05 4.3e-06 1.2e-03 3.8e-04
3 BLA mRNA stability ENSRNOG00000070180 0.16 0.1 1.2e-10 0.17 0.19 0.18 0.21 1.9e-09 2.2e-10 9.0e-10 1.5e-11
4 Brain gene expression ENSRNOG00000070180 0.27 0.12 0.0e+00 0.36 0.37 0.37 0.38 2.4e-35 3.4e-36 2.3e-36 1.4e-36
5 Brain mRNA stability ENSRNOG00000070180 0.1 0.06 1.8e-12 0.12 0.13 0.12 0.12 1.5e-11 5.3e-12 5.5e-11 2.4e-11
6 IL gene expression ENSRNOG00000070180 0.4 0.2 2.3e-09 0.22 0.29 0.26 0.22 5.2e-06 1.4e-07 7.1e-07 4.0e-06
7 LHb gene expression ENSRNOG00000070180 0.41 0.2 9.4e-07 0.23 0.19 0.2 0.22 2.7e-06 2.5e-05 1.3e-05 5.1e-06
8 NAcc gene expression ENSRNOG00000070180 0.75 0.12 0.0e+00 0.35 0.34 0.37 0.36 5.0e-27 6.9e-26 4.1e-29 1.1e-27
9 NAcc isoform ratio ENSRNOT00000083354 0.04 0.04 6.6e-03 0.01 0.02 0.02 0.02 7.3e-02 1.2e-02 1.1e-02 1.7e-02
10 NAcc isoform ratio ENSRNOT00000089544 0.03 0.03 9.8e-03 0.01 0.01 0.02 0.01 2.3e-02 8.0e-02 1.9e-02 9.7e-02
11 NAcc intron excision ratio chr7:129975357:129980205 0.05 0.04 3.1e-04 0.05 0.04 0.02 0.04 2.2e-04 1.1e-03 1.2e-02 1.1e-03
12 NAcc mRNA stability ENSRNOG00000070180 0.11 0.09 1.7e-07 0.08 0.07 0.07 0.07 2.4e-06 4.5e-06 9.7e-06 5.5e-06
13 OFC gene expression ENSRNOG00000070180 0.45 0.22 1.9e-05 0.11 0.12 0.11 0.12 1.3e-03 1.0e-03 1.5e-03 9.2e-04
14 PL gene expression ENSRNOG00000070180 0.39 0.19 0.0e+00 0.39 0.4 0.41 0.41 5.9e-31 1.1e-32 3.7e-33 5.3e-33
15 PL mRNA stability ENSRNOG00000070180 0.16 0.09 7.0e-15 0.18 0.19 0.18 0.19 2.3e-13 2.7e-14 1.9e-13 3.4e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail4.313.816.6-4.1-3.83.7-3.93.9-3.7-3.6-3.33.7-3.8-3.63.6-3.6-3.63.9
BMI without tail0.00.10.3-0.0-0.0-0.1-0.0-0.10.00.30.5-0.00.00.3-0.30.30.30.1
Body weight6.025.228.2-5.2-5.25.1-5.25.2-5.1-4.9-4.74.8-5.1-4.94.8-4.9-4.95.3
Epididymis fat weight0.20.40.9-0.8-0.50.6-0.50.6-0.5-0.6-0.60.9-0.7-0.70.6-0.6-0.60.6
Glucose0.00.10.2-0.1-0.40.3-0.20.2-0.4-0.10.1-0.1-0.2-0.10.2-0.1-0.10.4
Heart weight0.10.10.3-0.5-0.20.2-0.20.3-0.1-0.2-0.10.5-0.4-0.20.4-0.3-0.20.2
Left kidney weight0.51.44.0-1.7-0.91.0-1.11.2-0.9-1.0-0.92.0-1.5-1.00.9-0.9-1.11.1
Right kidney weight2.67.48.5-2.7-2.82.7-2.92.8-2.8-2.6-2.52.5-2.9-2.62.5-2.6-2.82.8
Tail length0.10.30.50.70.5-0.50.4-0.60.40.60.6-0.70.60.6-0.70.60.5-0.5
Length with tail1.97.07.3-2.6-2.72.7-2.72.7-2.7-2.7-2.62.5-2.7-2.72.6-2.7-2.72.7
Length without tail7.917.219.0-4.3-4.14.1-4.14.2-4.0-4.1-4.04.4-4.3-4.14.0-4.1-4.14.2
Liver weight, left1.93.03.5-1.7-1.81.8-1.71.8-1.7-1.6-1.61.7-1.9-1.61.7-1.7-1.71.8
Liver weight, right1.52.53.0-1.5-1.61.6-1.51.6-1.6-1.6-1.51.6-1.7-1.61.5-1.5-1.51.6
Parametrial fat weight2.04.04.91.82.1-2.12.0-2.02.12.12.2-1.41.92.1-2.02.12.1-2.0
Retroperitoneal fat weight0.41.42.40.71.2-1.21.2-1.11.21.41.5-0.00.61.3-1.51.41.3-1.0
Intraocular pressure7.710.812.13.43.3-3.33.2-3.33.23.23.1-3.43.53.3-3.33.33.2-3.3
Extensor digitorum longus weight3.714.818.6-3.7-4.24.0-3.93.9-4.1-3.6-3.43.5-4.0-3.63.8-3.8-3.74.3
Soleus weight0.51.61.9-1.1-1.41.3-1.31.3-1.3-1.3-1.10.9-1.3-1.31.3-1.3-1.31.3
Tibialis anterior weight0.72.54.4-1.3-2.11.8-1.71.6-2.0-1.4-1.01.1-1.6-1.41.4-1.4-1.32.1
Tibia length7.320.522.6-4.4-4.74.6-4.84.6-4.7-4.5-4.54.1-4.5-4.54.3-4.4-4.64.7
Number of licking bursts0.60.72.11.10.4-0.60.6-0.80.40.80.9-1.40.90.8-0.90.90.8-0.5
Food consumed during 24 hour testing period2.02.43.3-1.8-1.41.5-1.51.6-1.4-1.5-1.41.8-1.7-1.51.4-1.5-1.61.5
Times rat made contact with spout0.10.10.5-0.00.3-0.30.3-0.20.30.40.70.10.10.4-0.40.40.4-0.1
Mean time between licks in bursts0.10.10.20.30.4-0.30.4-0.30.40.1-0.2-0.20.40.1-0.10.20.2-0.4
Mean num. licks in bursts0.20.21.5-0.80.20.1-0.00.30.2-0.1-0.11.2-0.5-0.10.3-0.3-0.2-0.0
Std. dev. time between licks in bursts1.11.31.71.31.0-1.11.0-1.21.01.11.0-1.21.11.1-1.31.21.1-1.1
Water consumed over 24 hours0.00.00.1-0.2-0.00.1-0.10.2-0.1-0.2-0.20.3-0.3-0.20.1-0.2-0.20.0
Indifference point 0 sec2.33.64.31.81.9-2.01.8-1.91.91.92.1-1.81.92.0-1.91.91.9-1.9
Indifference point AUC0.30.30.80.60.5-0.50.3-0.60.40.50.6-0.90.60.5-0.60.60.4-0.5
Indifference point function ln k3.75.25.7-2.3-2.32.3-2.22.3-2.3-2.3-2.41.9-2.2-2.42.3-2.4-2.32.3
Indifference point function log k3.75.25.7-2.3-2.32.3-2.22.3-2.3-2.3-2.41.9-2.2-2.42.3-2.4-2.32.3
Delay discounting total patch changes 0 sec2.23.54.01.81.8-1.91.8-1.91.81.92.0-1.91.91.9-1.91.91.9-1.8
Delay discounting total patch changes 12 sec2.22.93.81.81.5-1.71.5-1.71.51.81.9-2.01.71.8-1.71.71.7-1.5
Delay discounting total patch changes 18 sec4.35.67.62.52.3-2.42.2-2.42.22.32.3-2.82.52.3-2.32.32.2-2.4
Delay discounting total patch changes 24 sec2.22.84.41.91.5-1.61.5-1.71.41.61.7-2.11.71.6-1.61.71.6-1.5
Delay discounting total patch changes 6 sec2.43.74.11.91.9-2.01.8-2.01.92.02.0-1.81.82.0-2.02.01.9-1.9
Delay discounting time to switch 0 sec2.23.44.11.91.8-1.92.0-1.91.91.81.6-1.62.01.8-1.71.82.0-1.9
Delay discounting water rate 0 sec2.84.55.2-2.1-2.22.2-2.32.1-2.3-2.1-1.91.8-2.3-2.12.0-2.0-2.22.2
Delay discounting water rate 12 sec3.85.76.3-2.3-2.42.4-2.42.4-2.4-2.5-2.52.0-2.3-2.52.4-2.4-2.52.3
Delay discounting water rate 18 sec0.30.30.5-0.5-0.70.6-0.60.6-0.6-0.5-0.50.5-0.7-0.50.5-0.6-0.50.7
Delay discounting water rate 24 sec3.04.14.9-1.7-2.22.2-2.02.0-2.2-2.2-2.11.4-1.8-2.22.0-2.1-2.12.1
Delay discounting water rate 6 sec3.75.35.9-2.2-2.42.4-2.32.3-2.4-2.4-2.31.9-2.3-2.42.2-2.3-2.42.3
Locomotor activity1.21.92.71.51.2-1.31.3-1.41.21.51.4-1.51.31.4-1.61.51.3-1.2
Locomotor testing distance3.15.16.32.42.2-2.22.2-2.32.12.32.2-2.32.22.2-2.52.42.2-2.2
Locomotor testing rearing2.64.15.62.31.8-1.91.9-2.11.81.91.9-2.42.21.9-2.22.12.0-1.9
Light reinforcement 13.05.47.52.72.2-2.22.2-2.42.12.32.3-2.62.32.3-2.32.32.2-2.3
Light reinforcement 20.91.11.61.11.0-1.11.0-1.11.11.31.1-0.60.91.2-1.11.11.1-1.0
Reaction time number correct1.62.33.2-1.4-1.41.5-1.51.5-1.4-1.6-1.81.3-1.5-1.71.5-1.6-1.71.3
Reaction time mean minus median8.210.711.82.93.4-3.43.3-3.33.43.33.4-2.73.13.4-3.33.43.4-3.3
Reaction time mean minus median AUC5.97.68.52.52.9-2.92.8-2.72.92.82.8-2.32.82.8-2.62.82.9-2.8
Reaction time num false alarms1.62.22.51.41.6-1.51.5-1.51.51.41.4-1.41.61.4-1.51.51.5-1.6
Reaction time num false alarms AUC2.23.13.81.51.9-1.81.8-1.81.91.71.6-1.41.81.7-1.81.81.8-1.9
Reaction time trials correct on left1.62.33.2-1.4-1.41.5-1.51.5-1.4-1.6-1.81.3-1.5-1.71.5-1.6-1.71.3
Reaction time trials on left1.31.82.6-1.2-1.21.4-1.31.3-1.2-1.5-1.61.2-1.3-1.51.3-1.5-1.51.1
Reaction time mean0.70.91.20.80.9-1.01.0-0.90.91.01.1-0.70.91.0-1.01.01.0-0.8
Reaction time mean AUC0.40.50.70.50.7-0.70.7-0.70.70.70.8-0.50.70.7-0.70.70.8-0.6
Median of all reaction times0.00.00.0-0.1-0.10.1-0.10.1-0.1-0.00.00.2-0.1-0.10.1-0.1-0.00.2
Reaction time omissions9.813.214.33.53.8-3.73.7-3.73.83.73.7-3.03.53.7-3.63.73.7-3.8
Reaction time false alarm rate2.73.84.21.72.0-2.02.0-1.92.01.92.0-1.62.02.0-2.02.02.0-1.9
Reaction time premature initiation rate6.89.210.43.22.8-3.02.8-3.12.83.23.2-2.92.93.2-3.23.13.0-2.8
Reaction time premature initiations3.14.45.52.31.9-2.11.9-2.21.92.22.1-2.12.12.1-2.32.12.0-2.0
Std. dev. reaction times6.18.49.12.63.0-3.03.0-2.93.02.93.0-2.42.93.0-2.93.03.0-2.9
Reaction time trials completed1.31.82.6-1.2-1.21.4-1.31.3-1.2-1.5-1.61.2-1.3-1.51.3-1.5-1.51.1
Reaction time trials AUC2.02.83.9-1.5-1.51.7-1.61.6-1.6-1.8-2.01.4-1.6-1.91.7-1.8-1.91.4
Social response proportion0.10.10.30.20.3-0.40.4-0.30.30.50.50.00.30.5-0.40.40.4-0.3
Social responses8.110.411.13.33.1-3.33.1-3.33.13.33.2-3.13.33.3-3.33.33.3-3.1
Social time0.00.10.5-0.40.1-0.10.10.10.20.20.30.7-0.20.20.0-0.00.1-0.0
Conditioned locomotion0.10.10.50.3-0.30.2-0.20.1-0.4-0.2-0.4-0.70.1-0.20.2-0.2-0.30.2
Cocaine response after cond. corrected0.10.11.5-0.60.2-0.10.10.10.30.0-0.01.2-0.40.0-0.00.10.1-0.0
Cocaine response after cond. not corrected0.50.50.90.21.0-0.80.8-0.61.00.70.70.40.40.7-0.70.80.8-0.8
Cocaine response before conditioning3.74.56.12.32.1-2.22.0-2.22.02.02.0-2.52.32.0-2.02.02.0-2.2
Saline control response0.10.20.3-0.4-0.30.4-0.40.4-0.4-0.5-0.60.2-0.2-0.50.4-0.5-0.50.3
Condit. Reinf. active minus inactive responses0.00.00.20.30.2-0.10.1-0.20.10.10.1-0.40.20.1-0.10.10.0-0.2
Condit. Reinf. active-inactive response ratio0.30.40.50.50.6-0.60.6-0.60.60.60.7-0.60.60.6-0.50.60.6-0.6
Condit. Reinf. active responses0.20.30.70.60.5-0.50.4-0.60.50.40.5-0.80.60.4-0.50.50.4-0.6
Condit. Reinf. inactive responses0.70.91.81.10.8-0.90.9-1.00.80.80.8-1.31.10.8-0.90.90.8-0.9
Condit. Reinf. lever presses0.00.00.10.00.0-0.00.0-0.00.0-0.1-0.1-0.20.1-0.10.00.0-0.0-0.1
Condit. Reinf. lever reinforcers received0.50.71.11.00.9-0.80.8-0.90.80.80.8-1.10.90.8-0.80.80.8-1.0
Pavlov. Cond. lever latency0.00.00.1-0.1-0.10.1-0.10.1-0.1-0.1-0.20.2-0.2-0.10.2-0.2-0.20.0
Pavlov. Cond. magazine entry latency1.11.21.4-1.1-1.11.1-1.21.1-1.1-1.1-1.10.8-1.1-1.11.2-1.2-1.21.1
Pavlov. Cond. change in total contacts1.31.82.4-1.5-1.41.4-1.41.4-1.4-1.3-1.01.3-1.4-1.31.3-1.2-1.31.6
Pavlov. Cond. index score0.40.60.7-0.8-0.80.8-0.80.8-0.8-0.8-0.60.5-0.7-0.80.8-0.7-0.80.8
Pavlov. Cond. latency score0.50.60.8-0.9-0.80.8-0.80.8-0.8-0.8-0.60.6-0.8-0.80.8-0.8-0.80.9
Pavlov. Cond. lever contacts0.10.20.30.30.4-0.40.4-0.40.40.40.5-0.30.40.4-0.50.50.4-0.3
Pavlov. Cond. magazine entry number2.12.62.91.51.7-1.71.7-1.61.71.61.5-1.11.61.6-1.71.61.7-1.7
Pavlov. Cond. intertrial magazine entries5.16.67.62.42.6-2.62.6-2.62.62.62.8-2.22.42.6-2.72.72.7-2.6
Pavlov. Cond. lever-magazine prob. diff.0.81.01.3-1.0-1.11.1-1.11.1-1.1-1.0-0.90.7-0.9-1.01.1-1.0-1.01.1
Pavlov. Cond. response bias0.00.00.00.10.0-0.10.0-0.10.00.10.2-0.10.10.1-0.10.10.1-0.0
Conditioned reinforcement - actives1.81.82.41.31.2-1.31.1-1.31.21.51.5-1.51.31.5-1.41.31.3-1.2
Conditioned reinforcement - inactives2.02.33.21.31.5-1.61.4-1.51.51.71.8-1.21.31.7-1.71.61.5-1.4
Conditioned locomotion0.50.61.80.90.6-0.80.5-0.70.60.90.9-1.30.90.9-0.70.60.6-0.7
Intermittent access intake day 1-15 change1.41.41.91.01.2-1.21.1-1.21.21.31.3-0.70.91.3-1.41.31.2-1.1
Intermittent access intake escalation0.90.91.40.81.0-1.00.9-1.01.01.11.1-0.40.71.1-1.21.11.0-0.9
Intermittent access intake escalation 21.51.52.11.01.3-1.21.2-1.21.21.41.4-0.60.91.4-1.41.41.2-1.1
Intermitt. access day 1 inactive lever presses3.13.35.52.21.7-1.81.9-1.91.81.61.5-2.32.21.6-1.51.51.8-1.9
Intermitt. access day 15 inactive lever presses1.31.41.81.31.2-1.21.2-1.21.11.21.1-1.21.31.2-1.21.11.1-1.2
Intermitt. access escalation Index0.20.20.50.60.4-0.40.7-0.50.40.30.2-0.30.60.3-0.40.50.6-0.4
Intermittent access day 1 total infusions1.21.41.71.01.2-1.21.2-1.11.21.31.3-1.01.11.3-1.21.11.2-1.1
Intermittent access day 15 total infusions2.73.03.71.61.7-1.81.7-1.81.71.91.9-1.51.61.9-1.91.81.7-1.6
Intermittent access terminal intake (last 3 days)3.03.23.81.71.8-1.81.7-1.81.81.92.0-1.61.71.9-1.91.91.8-1.7
Intermittent access total infusions2.73.03.61.71.7-1.81.7-1.71.71.91.9-1.51.71.9-1.81.81.7-1.6
Intermittent access day 1 locomotion1.11.12.31.30.9-1.11.0-1.10.91.01.0-1.51.31.0-0.90.91.0-1.0
Intermittent access day 15 total locomotion2.02.14.01.71.2-1.41.2-1.51.21.61.6-2.01.51.6-1.41.31.3-1.3
Intermittent access total locomotion4.04.57.82.51.8-2.11.9-2.11.82.22.1-2.82.42.2-2.02.02.0-2.0
Intermittent access standard deviation0.50.50.70.60.7-0.70.8-0.70.70.80.8-0.50.60.8-0.80.80.8-0.7
Cocaine induced anxiety1.01.21.4-0.9-1.21.1-1.11.1-1.2-1.1-1.10.8-1.1-1.11.1-1.1-1.11.2
Post-drug Anxiety4.95.45.9-2.2-2.42.4-2.32.4-2.4-2.4-2.41.9-2.2-2.42.4-2.4-2.42.4
Baseline Anxiety1.01.01.4-1.1-1.01.0-0.91.1-1.0-1.0-1.01.2-1.0-1.01.0-1.0-0.91.1
Lifetime Intake2.62.93.81.61.6-1.71.6-1.71.61.91.9-1.41.61.9-1.91.81.7-1.5
Incentive Sensitization - Responses0.00.00.10.0-0.20.1-0.30.0-0.20.10.1-0.1-0.10.1-0.2-0.0-0.20.2
Incentive Sensitization - Breakpoint0.00.00.10.2-0.00.0-0.1-0.1-0.10.20.2-0.20.00.2-0.30.1-0.10.0
Progressive ratio test 1 active lever presses4.95.05.62.42.1-2.22.2-2.32.12.42.4-2.22.22.4-2.32.32.3-2.1
Progressive ratio test 1 breakpoint4.54.65.32.32.0-2.22.1-2.22.02.32.3-2.22.12.3-2.22.22.2-2.0
Progressive ratio test 1 inactive lever presses4.14.44.82.22.0-2.12.0-2.12.02.22.1-2.22.22.2-2.12.12.0-2.0
Progressive ratio test 2 active lever presses2.72.93.51.91.5-1.61.6-1.71.51.81.7-1.91.81.8-1.71.71.7-1.5
Progressive ratio test 2 breakpoint3.43.84.62.11.7-1.91.9-2.01.72.02.0-2.12.12.0-2.01.91.9-1.8
Progressive ratio test 2 inactive lever presses2.83.23.71.91.7-1.81.7-1.81.71.91.9-1.91.91.9-1.81.71.7-1.7
Total sessions with >9 infusions1.01.11.80.90.9-1.00.8-1.00.81.31.3-0.80.71.3-1.31.21.0-0.8
Short access day 1 total inactive lever presses1.61.82.11.31.2-1.31.4-1.31.21.41.4-1.21.41.4-1.41.31.4-1.1
Short access day 10 total inactive lever presses0.30.41.00.90.5-0.50.7-0.60.50.40.3-1.00.90.4-0.30.30.6-0.6
Short access day 1 total infusions0.10.10.20.10.1-0.20.2-0.20.10.40.40.10.10.4-0.40.30.2-0.0
Short access day 10 total infusions1.01.11.80.91.0-1.10.9-1.01.01.31.3-0.70.81.3-1.21.21.1-0.8
Short access total infusions0.60.71.20.70.6-0.80.6-0.80.61.01.1-0.60.61.0-1.00.90.8-0.5
Short access day 1 locomotion0.20.20.30.60.2-0.30.3-0.40.20.50.5-0.60.40.5-0.40.40.4-0.2
Short access day 10 total locomotion0.40.41.91.00.3-0.50.4-0.60.30.40.4-1.40.90.4-0.30.40.5-0.5
Short access total locomotion0.70.71.81.10.5-0.80.7-0.80.50.90.8-1.31.00.9-0.70.70.7-0.6
Compulsive drug intake1.11.11.4-1.2-1.01.1-0.91.1-0.9-1.2-1.21.1-0.9-1.21.1-1.1-1.01.0
One hour access (0.3 mA shock)0.30.30.70.50.5-0.50.5-0.60.50.80.8-0.40.30.8-0.70.70.6-0.4
One hour access (shock baseline)0.20.30.60.40.4-0.50.3-0.50.30.70.8-0.40.20.7-0.70.60.4-0.3
Number of responses in last shaping day0.00.00.10.2-0.30.1-0.10.0-0.3-0.0-0.0-0.0-0.0-0.00.0-0.1-0.10.3
Context. condit. distance diff. score0.20.20.4-0.4-0.60.5-0.40.5-0.6-0.5-0.50.4-0.4-0.50.5-0.5-0.40.6
Locomotion velocity, session 11.11.21.71.21.0-1.11.1-1.11.01.10.9-1.31.21.1-1.01.01.0-1.1
Locomotion distance, session 12.53.34.31.52.0-2.02.0-1.82.11.91.6-1.11.91.9-1.71.71.8-2.0
Locomotion velocity, session 20.20.20.30.30.6-0.50.5-0.50.50.40.30.10.30.4-0.50.50.4-0.6
Locomotion distance, session 22.02.83.71.41.9-1.81.8-1.71.91.71.4-1.11.81.7-1.71.71.7-1.9
Locomotion velocity, session 33.64.24.91.92.2-2.12.1-2.12.22.12.0-1.31.92.1-2.22.12.1-2.1
Locomotion distance, session 34.65.06.02.22.4-2.32.3-2.32.42.22.0-1.62.12.2-2.42.42.2-2.4
Stereotopy head waving bouts, day 31.21.41.8-0.9-1.31.3-1.21.1-1.4-1.3-1.30.6-1.1-1.31.0-1.1-1.31.2
Stereotopy head waving duration, day 30.50.60.8-0.7-0.80.8-0.80.8-0.9-0.9-0.80.3-0.7-0.90.8-0.8-0.90.8
Locomotion velocity, session 70.20.20.40.60.4-0.40.5-0.50.40.40.2-0.40.40.4-0.60.60.4-0.4
Locomotion distance, session 71.62.02.71.61.4-1.41.5-1.51.31.41.2-1.31.51.4-1.61.61.4-1.4
Stereotopy head waving bouts, day 70.91.01.6-0.7-1.21.1-1.20.9-1.2-1.1-0.90.2-0.9-1.10.8-0.9-1.11.1
Stereotopy head waving duration, day 71.11.31.8-0.8-1.31.2-1.31.1-1.4-1.2-1.00.3-1.0-1.21.1-1.2-1.21.2
Locomotion velocity, session 80.00.00.0-0.1-0.10.0-0.00.1-0.00.0-0.00.2-0.00.00.1-0.10.00.1
Locomotion distance, session 81.01.52.01.01.4-1.41.3-1.21.41.31.0-0.71.41.3-1.21.21.3-1.3
Degree of sensitization distance0.40.40.6-0.5-0.80.7-0.70.7-0.8-0.7-0.60.3-0.5-0.70.7-0.7-0.60.8
Degree of sensitization stereotypy0.10.20.4-0.0-0.60.4-0.50.3-0.6-0.3-0.2-0.4-0.2-0.30.3-0.3-0.40.5
Condit. Reinf. active minus inactive responses0.00.10.2-0.10.3-0.20.3-0.10.30.20.20.5-0.00.2-0.20.20.2-0.2
Condit. Reinf. active-inactive response ratio0.40.41.5-0.8-0.40.5-0.40.6-0.4-0.6-0.71.2-0.7-0.60.6-0.6-0.50.4
Condit. Reinf. active responses0.50.60.70.60.8-0.80.9-0.80.80.80.8-0.30.70.8-0.80.80.8-0.8
Condit. Reinf. inactive responses2.93.44.01.91.8-1.91.8-1.91.81.91.9-2.02.01.9-1.81.81.9-1.8
Incentive salience index mean0.10.10.4-0.3-0.20.2-0.20.2-0.2-0.1-0.10.7-0.3-0.10.1-0.1-0.10.3
Condit. Reinf. lever presses0.10.20.5-0.5-0.50.5-0.40.4-0.5-0.3-0.30.7-0.4-0.30.3-0.3-0.30.6
Time in familiar zone, hab. session 10.30.30.40.30.6-0.50.6-0.50.60.50.5-0.30.60.5-0.50.50.6-0.5
Time in novel zone, hab. session 10.30.20.4-0.1-0.60.5-0.60.4-0.6-0.5-0.6-0.3-0.3-0.50.5-0.5-0.50.5
Total zone transitions, hab. session 10.30.50.80.70.7-0.70.7-0.70.70.70.5-0.80.90.7-0.60.60.7-0.7
Total locomotion distance, hab. session 10.00.00.3-0.20.00.1-0.10.1-0.0-0.2-0.50.3-0.0-0.20.2-0.2-0.2-0.0
Locomotion velocity, hab. session 10.10.10.4-0.2-0.10.2-0.20.2-0.1-0.3-0.60.3-0.1-0.30.3-0.3-0.30.1
Time in familiar zone, hab. session 20.30.30.7-0.8-0.40.5-0.60.6-0.4-0.6-0.50.7-0.6-0.60.6-0.7-0.60.5
Time in novel zone, hab. session 20.40.41.21.00.3-0.50.5-0.60.30.50.4-1.10.70.5-0.50.50.5-0.5
Total zone transitions, hab. session 20.20.30.50.40.7-0.60.6-0.50.70.60.4-0.00.50.6-0.60.60.6-0.6
Total locomotion distance, hab. session 20.10.10.20.00.4-0.30.3-0.20.40.1-0.20.40.20.1-0.30.20.1-0.4
Locomotion velocity, hab. session 20.00.00.3-0.20.2-0.10.2-0.10.2-0.1-0.30.60.0-0.1-0.10.10.0-0.2
Novel to familiar place preference ratio1.51.62.1-1.0-1.41.3-1.31.3-1.4-1.3-1.10.8-1.2-1.31.4-1.3-1.21.4
Novelty place preference1.11.11.5-0.7-1.21.1-1.11.0-1.2-1.1-0.90.5-0.9-1.11.2-1.1-1.01.1
Time in novel zone, NPP test0.80.91.3-0.6-1.11.0-0.90.9-1.1-1.0-0.80.3-0.8-1.01.1-1.0-0.91.0
Total zone transitions, NPP test1.11.62.11.01.4-1.41.4-1.21.41.41.2-0.61.21.4-1.31.31.3-1.3
Total locomotion distance, NPP test1.41.92.61.21.6-1.51.5-1.41.61.31.0-0.71.41.3-1.41.41.4-1.6
Locomotion velocity, NPP test0.71.01.40.81.2-1.11.1-1.01.21.00.7-0.31.01.0-1.11.11.0-1.1
Pavlov. Cond. lever latency0.10.10.5-0.1-0.10.2-0.20.3-0.1-0.4-0.7-0.20.1-0.40.6-0.6-0.30.0
Pavlov. Cond. magazine entry latency0.00.00.4-0.30.10.0-0.00.10.1-0.00.10.6-0.3-0.00.1-0.1-0.10.0
Pavlov. Cond. change in total contacts0.00.00.1-0.2-0.20.2-0.10.1-0.2-0.00.20.3-0.3-0.0-0.10.0-0.10.3
Pavlov. Cond. index score0.00.10.3-0.2-0.30.2-0.20.1-0.3-0.00.30.5-0.4-0.0-0.10.1-0.10.3
Pavlov. Cond. latency score0.00.10.2-0.2-0.20.2-0.20.1-0.20.00.30.5-0.40.0-0.30.2-0.00.3
Pavlov. Cond. lever contacts0.50.61.40.60.6-0.70.7-0.70.60.91.2-0.30.40.9-1.00.90.8-0.5
Pavlov. Cond. magazine entry number0.00.00.10.0-0.10.1-0.10.1-0.1-0.2-0.4-0.30.1-0.20.2-0.2-0.20.0
Pavlov. Cond. intertrial magazine entries0.30.30.50.40.7-0.70.7-0.50.70.60.5-0.20.40.6-0.50.50.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.20.30.7-0.6-0.60.5-0.50.5-0.5-0.3-0.00.8-0.8-0.30.2-0.2-0.40.7
Pavlov. Cond. response bias0.10.10.30.00.3-0.20.3-0.20.30.30.50.4-0.10.3-0.40.40.3-0.2
Bone: apparent density11.118.420.6-4.5-4.14.3-4.24.3-4.1-4.3-4.34.5-4.4-4.34.2-4.2-4.34.2
Bone surface12.622.223.6-4.9-4.64.8-4.74.8-4.6-4.8-4.74.7-4.8-4.84.6-4.7-4.84.7
Bone volume9.616.317.5-4.2-3.94.1-4.04.1-3.9-4.1-4.04.1-4.2-4.13.9-3.9-4.13.9
Bone: connectivity density8.012.614.9-3.9-3.33.5-3.53.6-3.3-3.6-3.63.8-3.6-3.63.5-3.5-3.63.4
Bone: cortical apparent density0.30.40.90.80.6-0.60.7-0.70.50.50.3-1.00.90.5-0.60.70.6-0.7
Bone: cortical area9.614.516.3-3.8-3.94.0-3.93.9-3.9-3.8-3.53.4-4.0-3.83.6-3.7-3.84.0
Bone: cortical porosity0.80.91.31.11.0-1.00.9-1.01.00.80.8-1.20.90.8-0.70.70.7-1.2
Bone: cortical porosity1.21.31.91.41.2-1.21.1-1.21.21.00.9-1.31.11.0-1.01.00.9-1.4
Bone: cortical thickness3.55.87.0-2.5-2.52.5-2.52.5-2.5-2.3-2.02.3-2.7-2.32.1-2.2-2.32.6
Bone: cortical thickness0.10.20.4-0.5-0.40.4-0.40.4-0.4-0.3-0.20.6-0.5-0.30.2-0.2-0.30.5
Bone: cortical tissue density0.40.61.11.00.7-0.70.8-0.80.70.60.3-1.11.00.6-0.70.70.7-0.8
Bone: elastic displacement4.44.96.02.32.3-2.32.5-2.32.32.22.1-1.92.32.2-2.02.12.3-2.4
Bone: elastic work0.00.00.10.10.00.00.20.00.1-0.2-0.40.20.0-0.20.3-0.2-0.0-0.1
Bone: endosteal estimation7.716.618.5-3.8-4.14.1-4.14.1-4.2-4.2-4.33.5-3.9-4.24.2-4.2-4.24.0
Bone: endosteal perimeter6.613.514.9-3.5-3.83.8-3.83.7-3.9-3.7-3.52.9-3.6-3.73.6-3.7-3.83.8
Bone: final force10.316.918.1-4.2-4.14.1-4.14.2-4.0-4.1-4.14.0-4.1-4.14.1-4.1-4.14.1
Bone: final moment10.918.019.4-4.4-4.14.3-4.24.3-4.1-4.3-4.34.2-4.2-4.34.3-4.3-4.34.2
Bone: marrow area7.516.218.1-3.7-4.14.1-4.14.0-4.1-4.2-4.33.4-3.8-4.24.1-4.1-4.24.0
Bone: maximum diameter3.66.67.8-2.4-2.82.7-2.82.6-2.8-2.5-2.22.1-2.8-2.52.3-2.5-2.62.8
Bone: maximum force14.625.428.0-5.0-5.05.1-5.05.1-5.0-5.1-5.34.6-4.8-5.15.1-5.2-5.14.9
Bone: maximum moment15.226.530.0-5.1-5.05.2-5.15.2-5.0-5.3-5.54.7-4.9-5.35.3-5.3-5.35.0
Bone: minimum diameter8.916.417.9-3.8-4.24.2-4.24.1-4.2-4.1-4.13.2-3.9-4.14.0-4.1-4.24.2
Bone: periosteal estimation12.024.525.9-4.8-5.05.1-5.15.0-5.1-5.0-4.94.4-5.0-5.04.8-4.9-5.15.0
Bone: periosteal perimeter10.317.118.6-4.2-4.24.2-4.24.2-4.2-4.1-3.93.8-4.3-4.14.0-4.1-4.24.2
Bone: post-yield work8.311.314.1-3.0-3.43.4-3.53.4-3.4-3.5-3.72.3-2.9-3.53.6-3.6-3.63.3
Bone: stiffness17.227.229.3-5.2-5.25.3-5.35.3-5.2-5.3-5.44.7-5.1-5.35.2-5.3-5.45.2
Bone: tissue strength1.21.12.0-1.0-1.01.0-0.91.1-1.0-1.2-1.40.8-0.7-1.21.3-1.2-1.10.9
Bone: trabecular number7.211.214.4-3.8-2.93.3-3.23.4-3.0-3.4-3.53.8-3.4-3.43.3-3.3-3.43.1
Bone: trabecular spacing2.73.55.62.31.5-1.81.7-1.91.61.92.0-2.41.81.9-1.81.81.8-1.7
Bone: trabecular thickness0.10.10.20.00.4-0.30.3-0.30.40.30.30.20.20.3-0.40.40.3-0.3
Bone: trabecular tissue density0.10.10.40.60.3-0.20.3-0.40.20.20.1-0.60.30.2-0.30.30.2-0.4
Breakpoint value in progressive ratio session0.20.20.4-0.4-0.50.4-0.50.5-0.5-0.5-0.40.3-0.5-0.40.7-0.5-0.40.5
Distance traveled before self-admin1.21.31.91.31.0-1.11.1-1.21.01.11.0-1.41.31.1-1.21.21.1-1.1
Distance traveled after self-admin0.20.20.20.40.5-0.50.4-0.40.40.40.4-0.30.50.4-0.50.50.4-0.4
Delta time in closed arm before/after self-admin0.40.41.4-1.0-0.40.5-0.50.6-0.4-0.5-0.41.2-0.9-0.50.5-0.6-0.50.5
Delta time in open arm before/after self-admin4.64.45.12.32.0-2.12.1-2.12.02.22.1-2.12.22.1-2.02.02.1-2.0
Diff in mean of infusions in LGA sessions1.61.82.2-1.5-1.31.4-1.21.4-1.2-1.4-1.31.2-1.4-1.31.4-1.4-1.31.3
Extinction: sum of active levers before priming0.40.40.7-0.5-0.70.7-0.60.6-0.7-0.7-0.70.3-0.6-0.70.8-0.7-0.70.6
Active lever presses in extinction session 60.50.50.6-0.8-0.70.7-0.70.7-0.7-0.7-0.60.8-0.7-0.60.7-0.7-0.70.7
Delta distance traveled before/after self-admin0.10.10.4-0.6-0.20.2-0.30.3-0.2-0.3-0.20.6-0.3-0.30.3-0.3-0.30.2
Delta ambulatory time before/after self-admin0.00.00.1-0.2-0.00.1-0.10.1-0.1-0.00.00.3-0.1-0.00.0-0.0-0.10.1
Time in closed arm before self-admin1.31.52.0-0.9-1.41.2-1.31.2-1.4-1.2-1.30.9-1.2-1.21.2-1.2-1.31.3
Time in closed arm after self-admin0.70.81.0-0.9-0.80.8-0.90.9-0.8-0.9-0.91.0-1.0-0.90.9-0.9-0.90.8
Time in open arm before self-admin0.70.81.0-0.9-0.80.9-0.80.9-0.8-1.0-0.90.7-0.9-0.90.9-0.9-0.80.8
Time in open arm after self-admin0.30.40.90.70.5-0.50.6-0.60.50.60.6-0.90.80.6-0.40.50.6-0.5
Sum of active levers in priming session hrs 5-60.00.00.10.10.2-0.30.2-0.10.30.10.1-0.10.20.2-0.00.10.2-0.2
Time to tail flick, vehicle, before self-admin0.80.81.20.81.1-1.01.0-0.91.10.90.9-0.60.90.9-0.70.90.9-1.1
Time to tail flick, vehicle, after self-admin0.20.20.5-0.1-0.60.5-0.50.4-0.6-0.5-0.70.2-0.4-0.50.4-0.5-0.50.5
Time to tail flick, test, before self-admin0.30.30.50.40.6-0.60.6-0.50.70.60.6-0.60.50.6-0.50.40.5-0.6
Time to tail flick, test, after self-admin0.20.20.4-0.5-0.40.4-0.50.5-0.4-0.5-0.50.6-0.6-0.40.5-0.5-0.50.4
Delta time to tail flick, vehicle, before/after SA0.40.40.5-0.5-0.70.7-0.60.6-0.7-0.6-0.70.6-0.6-0.60.4-0.6-0.60.7
Delta time to tail flick, test, before/after SA0.20.20.2-0.3-0.40.4-0.40.4-0.5-0.5-0.50.5-0.4-0.40.4-0.3-0.40.4
Ambulatory time before self-admin4.24.45.32.32.0-2.02.1-2.12.02.01.9-2.32.32.0-2.02.02.1-2.0
Ambulatory time after self-admin1.92.12.71.71.3-1.41.4-1.51.31.41.4-1.51.51.4-1.51.51.4-1.4
Total heroin consumption1.61.92.7-1.0-1.61.5-1.51.4-1.6-1.5-1.30.5-1.3-1.41.6-1.5-1.41.5
Area under the delay curve1.01.01.6-1.2-1.01.0-1.11.1-1.0-0.8-1.01.1-1.0-1.00.9-0.9-1.01.1
Delay disc. indifference point, 0s delay1.11.21.6-1.0-1.21.2-1.21.1-1.2-1.0-1.10.7-1.1-1.11.1-1.1-1.21.1
Delay disc. indifference point, 16s delay0.90.91.1-0.9-1.01.0-1.01.0-1.0-0.8-0.80.8-0.9-0.80.9-0.9-0.91.1
Delay disc. indifference point, 2s delay1.41.52.2-1.2-1.21.3-1.21.2-1.2-1.3-1.51.0-1.0-1.41.3-1.3-1.31.2
Delay disc. indifference point, 24s delay1.31.31.7-1.1-1.21.1-1.31.2-1.2-1.1-1.10.7-1.1-1.11.1-1.1-1.21.2
Delay disc. indifference point, 4s delay0.30.41.0-0.9-0.40.6-0.50.6-0.4-0.4-0.71.0-0.5-0.60.5-0.5-0.50.5
Delay disc. indifference point, 8s delay2.72.83.7-1.9-1.61.7-1.71.7-1.6-1.5-1.61.7-1.8-1.51.5-1.5-1.61.8
Delay discount exponential model param0.90.91.51.20.9-1.01.0-1.00.90.81.0-1.00.90.9-0.90.90.9-1.0
Delay discount hyperbolic model param0.90.91.41.20.9-1.01.0-1.00.90.81.0-1.00.90.9-0.90.90.9-1.0
Fecal boli incidents, locomotor time 11.92.03.30.71.6-1.41.5-1.31.71.61.8-0.21.01.6-1.61.51.5-1.4
Change in fecal boli incidents, locomotor task1.41.41.8-1.0-1.21.1-1.21.2-1.2-1.2-1.30.8-1.0-1.21.3-1.3-1.31.1
Time >=10cm from walls, locomotor time 10.20.20.5-0.7-0.30.4-0.40.5-0.3-0.4-0.40.7-0.5-0.40.4-0.3-0.40.4
Bouts of movement, locomotor time 10.10.10.5-0.3-0.00.00.00.20.0-0.10.20.7-0.40.10.2-0.10.00.1
Total resting periods, locomotor time 10.20.20.40.10.5-0.50.5-0.30.50.40.60.20.10.6-0.30.30.5-0.4
Rest time, locomotor task time 10.30.40.80.30.6-0.60.6-0.50.70.60.9-0.20.50.7-0.50.60.7-0.5
Distance moved, locomotor task time 10.00.00.20.1-0.10.2-0.20.1-0.2-0.3-0.3-0.40.1-0.30.2-0.2-0.30.0
Vertical activity count, locomotor time 11.51.62.1-1.4-1.11.3-1.31.2-1.2-1.1-1.21.5-1.4-1.21.1-1.2-1.31.2
Time >=10cm from walls, locomotor time 20.60.60.90.70.8-0.70.7-0.80.81.00.8-0.60.60.8-0.90.90.7-0.7
Bouts of movement, locomotor time 22.32.53.0-1.4-1.71.7-1.71.6-1.7-1.6-1.60.9-1.5-1.61.7-1.7-1.61.7
Total resting periods, locomotor time 22.72.93.4-1.5-1.81.8-1.81.7-1.9-1.7-1.71.0-1.5-1.71.8-1.8-1.71.8
Rest time, locomotor task time 20.00.00.1-0.3-0.20.2-0.10.2-0.1-0.2-0.10.3-0.1-0.10.1-0.1-0.00.2
Distance moved, locomotor task time 20.10.10.20.40.3-0.30.3-0.30.30.20.2-0.40.30.2-0.20.20.2-0.4
Vertical activity count, locomotor time 20.00.00.1-0.1-0.20.2-0.30.1-0.20.0-0.10.0-0.3-0.1-0.0-0.1-0.30.2
Weight adjusted by age1.82.02.9-1.1-1.71.5-1.61.4-1.7-1.4-1.30.5-1.1-1.41.3-1.4-1.51.6
Seeking ratio, delayed vs. immediate footshock0.40.51.5-1.0-0.50.6-0.60.7-0.5-0.6-0.41.2-0.9-0.50.5-0.5-0.60.6
Locomotion in novel chamber0.50.60.8-0.7-0.90.9-0.90.8-0.9-0.8-0.80.5-0.8-0.80.7-0.7-0.80.8
Locomotion in novel chamber post-restriction0.00.00.1-0.1-0.20.2-0.20.1-0.2-0.1-0.20.1-0.1-0.20.1-0.1-0.20.1
Progressive ratio0.00.00.2-0.00.3-0.20.1-0.20.20.10.30.2-0.00.2-0.40.30.1-0.2
Food seeking constrained by brief footshock0.30.40.80.60.6-0.70.7-0.60.60.70.9-0.10.40.8-0.70.70.7-0.5
Seeking ratio, punishment vs. effort0.00.00.00.2-0.0-0.10.2-0.10.00.10.1-0.10.10.10.1-0.00.20.0
Run reversals in cocaine runway, females0.00.00.40.20.0-0.10.0-0.10.10.10.2-0.60.20.10.1-0.10.1-0.1
Run reversals in cocaine runway, males1.61.51.61.31.2-1.31.2-1.31.21.21.2-1.21.21.2-1.21.21.2-1.2
Latency to leave start box in cocaine runway0.00.00.10.10.1-0.10.0-0.10.10.10.1-0.20.10.1-0.20.20.1-0.1
Latency to leave start box in cocaine runway, F1.92.12.61.61.4-1.41.4-1.51.31.41.3-1.61.51.3-1.51.51.4-1.5
Latency to leave start box in cocaine runway, M2.12.02.6-1.6-1.41.4-1.51.5-1.4-1.4-1.21.4-1.5-1.41.4-1.4-1.41.4
Cd content in liver0.60.70.90.80.7-0.80.8-0.90.80.90.8-0.40.70.9-1.00.90.9-0.7
Co content in liver0.60.71.80.80.5-0.70.7-0.80.61.11.3-0.60.61.1-1.11.01.0-0.4
Cu content in liver0.70.81.7-0.9-1.00.9-0.60.9-0.9-0.7-0.61.3-1.0-0.71.0-0.9-0.71.1
Fe content in liver0.40.51.00.60.5-0.60.7-0.60.60.81.0-0.60.70.8-0.70.70.9-0.4
K content in liver0.30.30.9-0.6-0.50.5-0.50.5-0.5-0.3-0.21.0-0.7-0.30.4-0.4-0.40.6
Mg content in liver0.00.00.1-0.10.1-0.0-0.1-0.00.00.10.20.3-0.20.1-0.20.20.00.0
Mn content in liver0.10.10.2-0.1-0.20.3-0.20.2-0.2-0.4-0.40.1-0.2-0.40.3-0.4-0.30.1
Na content in liver0.10.10.20.40.1-0.20.3-0.30.10.30.2-0.20.40.3-0.10.30.4-0.1
Rb content in liver0.40.50.80.70.5-0.60.7-0.70.60.80.9-0.70.60.8-0.80.80.8-0.5
Se content in liver0.60.71.20.70.8-0.80.8-0.80.80.91.1-0.30.50.9-1.01.00.9-0.8
Sr content in liver0.30.30.5-0.5-0.70.6-0.60.5-0.7-0.5-0.40.5-0.7-0.50.3-0.4-0.60.7
Zn content in liver2.12.33.01.61.3-1.41.5-1.51.31.61.7-1.71.61.6-1.61.61.6-1.3