Hub : Genes

Knop1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression ENSRNOG00000070112 0.07 0.04 4.6e-05 0.06 0.04 0.04 0.05 3.3e-06 1.9e-04 7.3e-05 4.1e-05
2 IL alternative polyA ENSRNOT00000096905 0.3 0.17 8.1e-03 0.04 0.06 0.03 0.04 4.9e-02 1.8e-02 8.5e-02 3.4e-02
3 IL alternative polyA ENSRNOT00000118077 0.29 0.17 9.2e-03 0.02 0.04 0.02 0.04 1.2e-01 3.5e-02 1.0e-01 4.6e-02
4 LHb gene expression ENSRNOG00000070112 0.21 0.13 5.9e-03 0.03 -0 -0.01 0.02 7.4e-02 3.4e-01 7.1e-01 1.2e-01
5 Liver gene expression ENSRNOG00000070112 0.04 0.02 2.9e-03 0 0.01 0 0 3.4e-01 6.8e-03 1.8e-01 3.0e-01
6 NAcc gene expression ENSRNOG00000070112 0.1 0.05 6.8e-09 0.1 0.12 0.11 0.12 3.8e-08 1.6e-09 1.3e-08 1.8e-09
7 OFC isoform ratio ENSRNOT00000096905 0.34 0.15 8.5e-05 0.04 0.1 0.04 0.04 4.4e-02 2.1e-03 4.9e-02 4.2e-02
8 OFC isoform ratio ENSRNOT00000118077 0.34 0.14 9.7e-05 0.08 0.1 0.04 0.05 5.7e-03 2.2e-03 3.7e-02 2.8e-02
9 PL alternative polyA ENSRNOT00000096905 0.05 0.03 3.9e-03 0.02 0.03 0.02 0.02 1.8e-02 4.5e-03 1.1e-02 1.3e-02
10 PL alternative polyA ENSRNOT00000118077 0.05 0.03 5.3e-03 0.01 0.02 0.02 0.02 2.5e-02 6.7e-03 1.9e-02 2.1e-02
11 PL gene expression ENSRNOG00000070112 0.1 0.06 2.1e-06 0.07 0.07 0.07 0.07 7.4e-06 3.4e-06 3.9e-06 5.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
BMI with tail1.96.09.33.0-1.91.82.90.72.22.8-2.7-2.52.43.0
BMI without tail5.210.918.24.3-2.22.14.01.03.03.8-3.6-3.23.14.3
Body weight1.46.011.73.3-1.01.03.10.92.62.7-2.6-2.32.23.4
Epididymis fat weight0.61.53.71.4-0.30.31.41.20.70.7-0.5-1.91.91.5
Glucose0.61.02.30.11.5-1.50.01.40.2-1.11.1-0.90.90.4
Heart weight0.70.91.9-0.21.3-1.3-0.31.40.2-1.41.4-0.80.80.1
Left kidney weight2.26.314.03.4-0.10.03.71.63.22.1-2.0-2.32.33.5
Right kidney weight2.57.014.73.7-0.20.13.81.53.42.3-2.3-2.42.33.7
Tail length1.54.510.02.9-0.0-0.02.71.32.51.9-1.8-2.12.03.2
Length with tail0.31.02.31.40.6-0.61.30.71.40.7-0.7-0.70.71.5
Length without tail0.51.12.1-1.01.0-0.9-1.1-0.5-0.5-1.00.91.4-1.4-1.2
Liver weight, left0.20.30.60.5-0.70.60.60.10.00.6-0.6-0.80.80.6
Liver weight, right1.01.75.20.2-2.32.30.5-1.1-0.21.8-1.7-0.20.20.3
Parametrial fat weight2.44.68.93.00.6-0.62.92.22.10.9-0.8-2.72.72.8
Retroperitoneal fat weight0.51.76.30.70.3-0.30.71.9-0.4-0.50.6-2.52.51.2
Intraocular pressure0.30.40.90.3-0.90.90.3-0.40.11.0-0.9-0.20.10.4
Extensor digitorum longus weight2.610.620.54.5-1.51.54.3-0.44.44.3-4.3-0.80.63.8
Soleus weight1.64.69.03.01.2-1.22.82.03.00.9-0.9-1.91.93.0
Tibialis anterior weight4.013.828.85.3-0.20.25.41.75.13.5-3.5-2.82.75.2
Tibia length0.20.61.40.01.2-1.2-0.11.10.2-1.11.1-0.60.60.2
Number of licking bursts4.04.89.4-2.70.5-0.5-2.8-1.6-1.7-1.81.62.9-2.8-3.1
Food consumed during 24 hour testing period1.11.33.21.7-0.0-0.01.70.61.80.9-0.9-0.70.71.5
Times rat made contact with spout1.11.33.41.3-0.50.51.4-0.61.91.5-1.60.5-0.61.0
Mean time between licks in bursts0.30.51.4-0.1-1.21.2-0.4-0.9-0.50.4-0.40.5-0.5-0.6
Mean num. licks in bursts4.75.711.43.2-0.40.43.31.32.72.3-2.2-2.32.33.4
Std. dev. time between licks in bursts0.40.51.9-0.2-1.41.30.2-0.4-0.30.6-0.6-0.30.3-0.1
Water consumed over 24 hours1.51.86.2-0.9-0.30.4-0.8-1.90.00.3-0.52.5-2.5-1.3
Indifference point 0 sec0.91.54.00.80.9-0.90.81.80.2-0.50.6-2.02.01.2
Indifference point AUC0.60.71.40.70.6-0.60.81.11.2-0.10.2-1.01.01.0
Indifference point function ln k0.20.31.11.10.1-0.10.90.30.50.4-0.4-0.50.50.7
Indifference point function log k0.20.31.11.10.1-0.10.90.30.50.4-0.4-0.50.50.7
Delay discounting total patch changes 0 sec1.01.74.80.90.8-0.90.81.90.2-0.50.6-2.22.21.3
Delay discounting total patch changes 12 sec0.10.20.60.3-0.30.30.40.40.10.3-0.2-0.80.80.5
Delay discounting total patch changes 18 sec0.30.40.8-0.40.9-0.9-0.20.80.1-0.80.8-0.40.40.1
Delay discounting total patch changes 24 sec0.81.02.40.80.7-0.70.71.40.6-0.20.3-1.51.51.2
Delay discounting total patch changes 6 sec2.43.67.2-0.32.4-2.5-0.42.7-0.3-2.52.5-1.92.00.3
Delay discounting time to switch 0 sec2.43.77.5-1.6-1.61.7-1.7-2.7-2.00.5-0.62.5-2.5-2.3
Delay discounting water rate 0 sec0.10.20.50.5-0.10.00.50.50.50.2-0.2-0.70.70.7
Delay discounting water rate 12 sec1.42.04.41.31.0-1.11.22.01.0-0.20.3-2.12.11.8
Delay discounting water rate 18 sec0.40.61.70.60.4-0.40.71.00.1-0.10.1-1.31.30.9
Delay discounting water rate 24 sec0.40.61.40.50.9-0.90.71.01.2-0.10.1-0.70.71.1
Delay discounting water rate 6 sec0.91.22.70.41.6-1.60.21.60.7-1.31.3-0.90.90.4
Locomotor activity0.10.20.7-0.5-0.80.8-0.4-0.2-0.50.3-0.3-0.30.30.0
Locomotor testing distance0.20.31.00.1-0.40.40.20.50.00.2-0.1-1.01.00.6
Locomotor testing rearing0.20.30.7-0.6-0.80.7-0.40.0-0.80.1-0.0-0.70.7-0.0
Light reinforcement 10.20.31.1-0.7-0.10.1-0.50.4-1.1-0.50.6-0.80.8-0.2
Light reinforcement 20.20.31.1-0.2-0.10.1-0.10.7-0.6-0.30.4-1.01.10.2
Reaction time number correct0.50.62.0-1.1-0.40.4-1.1-0.7-1.4-0.40.40.5-0.5-1.1
Reaction time mean minus median0.20.20.60.80.3-0.40.50.60.6-0.10.2-0.50.50.4
Reaction time mean minus median AUC0.30.40.90.30.7-0.70.10.9-0.3-0.80.9-0.80.90.0
Reaction time num false alarms0.71.02.1-1.10.5-0.5-1.1-0.6-0.2-0.90.81.5-1.4-1.3
Reaction time num false alarms AUC0.50.81.8-1.0-0.10.1-1.0-0.8-0.4-0.50.41.3-1.3-1.2
Reaction time trials correct on left0.50.62.0-1.1-0.40.4-1.1-0.7-1.4-0.40.40.5-0.5-1.1
Reaction time trials on left0.50.62.1-1.0-0.40.4-1.0-0.7-1.4-0.40.40.5-0.5-1.1
Reaction time mean0.30.51.01.0-0.10.00.90.60.40.3-0.2-1.01.00.8
Reaction time mean AUC0.20.20.50.7-0.40.30.60.20.00.3-0.3-0.70.60.4
Median of all reaction times0.30.40.90.9-0.40.30.90.40.30.5-0.4-0.90.90.7
Reaction time omissions0.50.71.7-0.1-1.31.3-0.3-1.0-1.10.5-0.50.4-0.4-0.8
Reaction time false alarm rate0.20.31.3-0.40.1-0.1-0.4-0.60.5-0.10.11.1-1.1-0.6
Reaction time premature initiation rate1.01.32.71.6-0.50.51.4-0.41.61.6-1.60.2-0.21.2
Reaction time premature initiations0.50.81.80.9-0.70.80.7-1.00.61.3-1.30.7-0.70.4
Std. dev. reaction times0.30.51.01.00.3-0.30.80.80.5-0.00.1-1.01.00.7
Reaction time trials completed0.50.62.1-1.0-0.40.4-1.0-0.7-1.4-0.40.40.5-0.5-1.1
Reaction time trials AUC0.30.41.5-0.8-0.40.4-0.9-0.5-1.2-0.30.30.4-0.4-0.9
Social response proportion0.30.40.8-0.40.1-0.1-0.30.6-0.9-0.70.8-0.80.8-0.2
Social responses0.50.62.1-1.0-0.60.6-1.0-0.4-1.5-0.50.60.1-0.1-1.1
Social time0.81.02.0-1.20.6-0.6-1.3-0.0-1.4-1.31.30.5-0.4-1.2
Conditioned locomotion0.91.12.7-0.7-1.11.1-0.4-1.6-0.70.7-0.81.4-1.4-1.0
Cocaine response after cond. corrected0.10.20.3-0.30.3-0.3-0.4-0.2-0.3-0.50.40.5-0.5-0.6
Cocaine response after cond. not corrected0.10.10.20.5-0.10.20.2-0.20.40.4-0.40.2-0.20.1
Cocaine response before conditioning1.41.73.71.6-0.80.81.5-0.31.61.9-1.9-0.40.31.6
Saline control response0.10.20.4-0.60.0-0.1-0.60.3-0.6-0.50.6-0.40.4-0.3
Condit. Reinf. active minus inactive responses0.81.03.80.3-0.20.10.61.3-0.2-0.10.3-1.91.90.9
Condit. Reinf. active-inactive response ratio0.70.82.5-0.30.0-0.1-0.11.2-0.7-0.80.9-1.61.60.2
Condit. Reinf. active responses0.40.62.10.2-0.40.30.70.80.00.3-0.2-1.51.50.8
Condit. Reinf. inactive responses0.81.02.40.9-0.80.81.3-0.51.01.5-1.50.0-0.10.9
Condit. Reinf. lever presses0.91.32.61.2-0.70.71.30.70.61.0-0.9-1.61.61.4
Condit. Reinf. lever reinforcers received0.30.41.6-0.1-0.50.50.40.6-0.40.1-0.0-1.31.30.5
Pavlov. Cond. lever latency0.60.91.7-1.00.3-0.3-1.3-0.7-0.8-0.70.71.3-1.2-1.3
Pavlov. Cond. magazine entry latency1.51.83.2-1.3-1.01.1-1.3-1.8-1.20.1-0.21.8-1.8-1.7
Pavlov. Cond. change in total contacts0.60.92.0-0.20.7-0.8-0.01.4-0.5-1.01.1-1.41.40.3
Pavlov. Cond. index score0.10.10.3-0.2-0.50.5-0.2-0.2-0.50.1-0.1-0.00.0-0.3
Pavlov. Cond. latency score0.10.10.3-0.1-0.60.6-0.1-0.4-0.30.3-0.30.1-0.1-0.2
Pavlov. Cond. lever contacts0.81.01.71.1-0.80.71.30.50.61.0-0.9-1.31.31.3
Pavlov. Cond. magazine entry number1.31.63.21.70.1-0.11.80.81.71.0-1.0-1.21.11.8
Pavlov. Cond. intertrial magazine entries1.82.44.01.9-1.01.01.90.61.31.7-1.6-1.71.62.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.4-0.70.7-0.4-0.5-0.70.1-0.10.2-0.2-0.5
Pavlov. Cond. response bias0.10.20.40.1-0.70.60.20.0-0.30.3-0.3-0.50.50.2
Conditioned reinforcement - actives1.51.53.70.51.9-1.90.71.70.9-0.90.9-1.01.01.0
Conditioned reinforcement - inactives1.01.12.9-0.71.7-1.7-0.40.90.2-1.51.50.1-0.1-0.3
Conditioned locomotion0.10.10.3-0.40.6-0.6-0.30.1-0.1-0.40.40.2-0.2-0.2
Intermittent access intake day 1-15 change0.90.92.3-1.20.4-0.4-0.8-0.70.1-0.60.51.5-1.5-1.1
Intermittent access intake escalation0.60.61.5-1.10.6-0.6-0.6-0.40.2-0.70.61.2-1.2-0.9
Intermittent access intake escalation 20.90.92.1-1.40.4-0.4-0.7-0.60.0-0.70.61.5-1.4-1.2
Intermitt. access day 1 inactive lever presses0.40.41.2-1.10.8-0.8-0.60.30.2-0.80.70.3-0.3-0.2
Intermitt. access day 15 inactive lever presses0.30.31.10.5-0.10.10.8-0.11.10.8-0.80.1-0.20.7
Intermitt. access escalation Index0.50.51.10.8-0.40.41.00.40.80.6-0.6-0.70.70.8
Intermittent access day 1 total infusions1.11.23.30.90.2-0.31.21.30.50.4-0.3-1.81.81.5
Intermittent access day 15 total infusions0.30.30.8-0.10.7-0.80.50.90.4-0.40.4-0.70.70.5
Intermittent access terminal intake (last 3 days)0.40.40.9-0.20.7-0.70.50.90.4-0.40.4-0.80.80.5
Intermittent access total infusions1.01.12.50.50.7-0.71.11.40.70.00.0-1.61.61.3
Intermittent access day 1 locomotion1.31.33.90.90.3-0.41.01.50.40.00.1-2.02.01.4
Intermittent access day 15 total locomotion2.52.66.0-1.31.9-2.0-0.81.9-0.8-2.42.4-1.21.2-0.5
Intermittent access total locomotion1.51.75.30.10.8-0.80.72.00.0-0.80.9-2.32.31.0
Intermittent access standard deviation0.20.20.8-0.20.6-0.60.50.30.9-0.10.00.2-0.20.3
Cocaine induced anxiety0.10.10.2-0.4-0.30.3-0.2-0.0-0.3-0.30.3-0.00.0-0.5
Post-drug Anxiety0.70.71.7-0.51.2-1.2-0.21.0-0.2-1.31.3-0.50.6-0.2
Baseline Anxiety1.01.12.60.91.6-1.60.81.21.1-0.40.4-0.70.71.1
Lifetime Intake1.41.63.70.80.6-0.61.51.51.00.4-0.3-1.91.91.8
Incentive Sensitization - Responses0.10.10.3-0.2-0.40.40.0-0.2-0.50.4-0.4-0.20.20.1
Incentive Sensitization - Breakpoint0.10.10.2-0.2-0.30.30.1-0.1-0.50.3-0.3-0.30.30.1
Progressive ratio test 1 active lever presses0.40.41.50.2-0.0-0.00.60.80.10.2-0.1-1.21.20.8
Progressive ratio test 1 breakpoint0.40.41.40.1-0.0-0.00.60.70.10.2-0.1-1.21.20.7
Progressive ratio test 1 inactive lever presses0.30.30.70.3-0.10.10.60.60.50.3-0.2-0.80.80.7
Progressive ratio test 2 active lever presses0.40.41.30.00.3-0.30.50.8-0.0-0.00.1-1.11.10.7
Progressive ratio test 2 breakpoint0.30.41.3-0.20.3-0.30.40.8-0.1-0.00.1-1.11.10.7
Progressive ratio test 2 inactive lever presses0.30.41.1-0.50.3-0.40.10.9-0.3-0.40.5-1.01.00.3
Total sessions with >9 infusions3.13.47.62.40.3-0.32.61.22.31.6-1.5-1.71.62.8
Short access day 1 total inactive lever presses0.30.30.6-0.40.8-0.8-0.10.70.1-0.50.5-0.50.50.4
Short access day 10 total inactive lever presses0.91.01.8-1.31.1-1.1-1.10.1-0.3-1.31.20.8-0.8-0.9
Short access day 1 total infusions1.21.22.90.50.8-0.81.11.41.00.2-0.1-1.61.61.7
Short access day 10 total infusions1.21.32.91.70.1-0.11.60.81.30.9-0.9-1.21.21.7
Short access total infusions2.22.45.21.30.6-0.61.91.71.30.6-0.5-2.22.22.3
Short access day 1 locomotion0.40.50.90.41.0-1.00.40.90.6-0.30.3-0.70.70.8
Short access day 10 total locomotion1.31.42.91.0-0.80.81.40.80.81.0-0.9-1.71.71.5
Short access total locomotion2.72.87.71.10.8-0.91.52.30.8-0.10.3-2.82.82.0
Compulsive drug intake0.50.51.5-0.1-1.21.2-0.0-0.1-0.60.5-0.4-0.80.80.2
One hour access (0.3 mA shock)1.61.84.81.0-0.30.31.71.30.90.8-0.6-2.22.21.7
One hour access (shock baseline)0.50.61.3-0.51.1-1.10.11.00.2-0.90.9-0.50.50.1
Number of responses in last shaping day0.30.30.80.4-0.20.20.70.10.50.7-0.7-0.40.40.9
Context. condit. distance diff. score0.20.30.9-0.8-0.20.2-0.9-0.3-1.0-0.30.40.1-0.1-0.7
Locomotion velocity, session 10.20.20.60.50.8-0.70.50.20.6-0.10.10.2-0.20.2
Locomotion distance, session 10.70.91.91.4-0.10.11.20.80.70.7-0.6-1.31.21.3
Locomotion velocity, session 20.20.31.00.31.0-1.00.20.20.3-0.50.50.4-0.4-0.1
Locomotion distance, session 21.31.84.62.10.0-0.02.00.71.71.2-1.2-1.01.01.8
Locomotion velocity, session 30.30.30.70.80.1-0.10.80.20.60.6-0.6-0.40.40.8
Locomotion distance, session 30.70.81.80.1-0.90.90.3-1.10.61.3-1.30.9-0.90.2
Stereotopy head waving bouts, day 30.40.40.9-0.70.5-0.5-0.70.3-0.9-0.91.0-0.10.1-0.6
Stereotopy head waving duration, day 30.30.40.9-0.50.5-0.6-0.60.5-0.8-0.90.9-0.40.4-0.3
Locomotion velocity, session 71.71.85.01.2-1.21.31.2-1.11.12.2-2.20.4-0.51.0
Locomotion distance, session 70.70.91.9-0.3-0.91.0-0.3-1.40.31.0-1.11.3-1.3-0.3
Stereotopy head waving bouts, day 70.30.40.70.70.4-0.40.70.70.30.1-0.1-0.80.80.8
Stereotopy head waving duration, day 71.21.52.91.6-0.40.41.70.71.01.2-1.1-1.41.41.6
Locomotion velocity, session 80.10.10.20.40.5-0.50.20.30.3-0.10.1-0.20.20.3
Locomotion distance, session 80.10.20.50.7-0.20.20.60.10.40.5-0.5-0.40.40.6
Degree of sensitization distance0.70.71.7-0.41.0-1.0-0.51.1-0.4-1.31.3-0.70.7-0.1
Degree of sensitization stereotypy1.11.22.61.6-0.10.11.60.51.21.1-1.1-0.90.91.5
Condit. Reinf. active minus inactive responses0.10.10.5-0.3-0.20.1-0.40.1-0.7-0.30.3-0.30.3-0.3
Condit. Reinf. active-inactive response ratio0.20.20.6-0.0-0.70.70.0-0.3-0.70.4-0.3-0.30.3-0.1
Condit. Reinf. active responses0.10.10.3-0.30.1-0.2-0.40.3-0.5-0.50.6-0.30.3-0.2
Condit. Reinf. inactive responses0.10.10.3-0.10.4-0.4-0.20.50.1-0.60.6-0.30.3-0.0
Incentive salience index mean0.20.30.80.3-0.90.90.1-0.6-0.20.6-0.60.1-0.2-0.1
Condit. Reinf. lever presses0.60.92.1-0.0-1.41.4-0.1-1.3-0.40.9-0.90.8-0.8-0.5
Time in familiar zone, hab. session 11.41.33.2-0.41.7-1.7-0.51.3-0.1-1.81.8-0.40.4-0.3
Time in novel zone, hab. session 11.61.64.40.5-1.61.70.6-1.4-0.02.1-2.10.4-0.40.6
Total zone transitions, hab. session 12.43.36.12.51.1-1.12.41.92.20.6-0.5-2.01.92.5
Total locomotion distance, hab. session 14.46.312.43.30.8-0.83.22.52.81.1-1.0-3.03.03.5
Locomotion velocity, hab. session 13.65.29.82.90.5-0.62.82.42.30.9-0.8-3.03.03.1
Time in familiar zone, hab. session 20.30.30.60.50.3-0.30.70.60.80.1-0.1-0.50.50.7
Time in novel zone, hab. session 20.00.00.2-0.0-0.20.2-0.2-0.1-0.50.00.0-0.10.1-0.1
Total zone transitions, hab. session 22.02.65.02.20.6-0.72.11.61.70.6-0.6-1.91.92.2
Total locomotion distance, hab. session 22.73.66.82.60.9-0.92.41.92.20.7-0.6-2.12.12.6
Locomotion velocity, hab. session 22.93.97.82.80.6-0.72.71.82.41.0-0.9-2.12.12.8
Novel to familiar place preference ratio0.60.71.6-0.90.7-0.7-1.00.2-0.5-1.31.20.5-0.5-0.9
Novelty place preference0.80.81.7-0.80.9-0.9-1.00.2-0.3-1.31.30.7-0.7-1.0
Time in novel zone, NPP test0.70.71.8-0.80.9-0.9-0.90.4-0.4-1.31.30.4-0.3-0.9
Total zone transitions, NPP test1.21.83.82.00.4-0.51.61.21.60.7-0.7-1.51.41.9
Total locomotion distance, NPP test1.42.03.71.90.8-0.81.61.51.90.4-0.4-1.51.51.9
Locomotion velocity, NPP test1.21.73.31.80.8-0.81.61.31.80.3-0.3-1.31.21.7
Pavlov. Cond. lever latency2.93.710.5-0.73.2-3.2-0.52.10.2-2.72.6-0.50.5-0.1
Pavlov. Cond. magazine entry latency3.74.812.31.5-3.53.51.3-1.60.43.2-3.1-0.40.31.1
Pavlov. Cond. change in total contacts4.74.912.40.2-3.53.50.2-2.80.03.0-3.01.4-1.4-0.1
Pavlov. Cond. index score3.95.014.70.8-3.83.80.6-2.3-0.23.1-3.00.3-0.40.3
Pavlov. Cond. latency score3.34.212.20.9-3.53.50.7-2.0-0.12.9-2.80.2-0.20.4
Pavlov. Cond. lever contacts4.24.913.70.9-3.73.70.7-2.4-0.03.2-3.10.5-0.60.3
Pavlov. Cond. magazine entry number3.94.813.2-0.73.6-3.6-0.62.40.0-3.13.1-0.70.7-0.3
Pavlov. Cond. intertrial magazine entries2.12.55.7-1.12.1-2.2-1.01.6-0.7-2.42.4-0.60.7-0.5
Pavlov. Cond. lever-magazine prob. diff.4.35.415.81.0-4.03.90.9-2.2-0.03.3-3.20.2-0.20.5
Pavlov. Cond. response bias4.85.915.70.7-4.04.00.6-2.8-0.03.4-3.40.9-1.00.1
Bone: apparent density0.71.12.51.60.2-0.21.50.81.20.7-0.6-1.11.11.5
Bone surface0.61.12.11.5-0.50.51.4-0.11.31.4-1.4-0.40.31.3
Bone volume1.11.84.02.0-0.10.12.00.61.81.3-1.3-1.01.01.9
Bone: connectivity density0.40.61.01.0-0.60.61.00.10.61.0-0.9-0.60.60.9
Bone: cortical apparent density0.50.71.4-1.20.5-0.5-1.1-0.2-0.6-1.00.90.8-0.8-1.0
Bone: cortical area2.13.27.12.7-0.10.12.50.82.41.7-1.7-1.31.32.5
Bone: cortical porosity0.70.81.21.0-0.80.81.00.20.31.1-1.0-1.01.01.1
Bone: cortical porosity0.40.40.70.5-0.80.80.50.0-0.30.8-0.7-0.80.80.6
Bone: cortical thickness1.21.94.61.91.1-1.11.81.32.10.4-0.4-1.01.01.9
Bone: cortical thickness1.21.44.30.52.1-2.00.61.41.4-1.00.9-0.40.40.8
Bone: cortical tissue density0.60.71.5-1.20.5-0.5-1.2-0.2-0.6-1.00.90.8-0.8-1.0
Bone: elastic displacement0.80.92.1-0.41.4-1.4-0.60.9-0.5-1.51.5-0.20.3-0.4
Bone: elastic work0.30.40.60.80.6-0.60.80.70.80.0-0.0-0.50.50.8
Bone: endosteal estimation1.22.75.51.8-1.71.71.9-0.51.42.4-2.3-0.70.61.6
Bone: endosteal perimeter1.02.14.71.6-1.71.71.3-1.11.22.1-2.20.3-0.30.9
Bone: final force3.65.912.83.3-0.40.43.61.23.22.3-2.2-2.01.93.3
Bone: final moment3.15.111.03.0-0.20.23.31.32.91.9-1.9-2.12.03.1
Bone: marrow area1.12.45.01.7-1.61.61.8-0.51.32.2-2.2-0.60.51.5
Bone: maximum diameter1.42.55.72.4-0.90.82.10.31.81.8-1.8-1.11.12.0
Bone: maximum force2.84.910.63.1-0.20.23.31.13.12.1-2.1-1.71.73.0
Bone: maximum moment2.44.19.02.8-0.10.13.01.22.71.7-1.7-1.81.72.8
Bone: minimum diameter1.42.54.82.1-1.21.22.0-0.31.72.2-2.2-0.60.61.8
Bone: periosteal estimation2.14.27.92.8-1.21.22.80.22.42.5-2.5-1.21.12.6
Bone: periosteal perimeter1.22.03.92.0-1.21.21.8-0.11.31.9-1.9-0.80.81.6
Bone: post-yield work1.82.44.51.8-1.01.01.80.90.81.4-1.3-2.12.12.0
Bone: stiffness2.33.68.82.70.2-0.22.91.03.01.6-1.6-1.21.12.5
Bone: tissue strength0.10.10.10.10.1-0.10.2-0.20.30.2-0.20.4-0.40.0
Bone: trabecular number0.50.71.61.20.4-0.51.20.81.20.3-0.3-0.80.81.1
Bone: trabecular spacing1.21.52.9-1.2-1.71.7-1.1-1.5-1.50.5-0.40.8-0.8-1.3
Bone: trabecular thickness3.74.48.42.01.9-2.02.12.91.7-0.60.7-2.72.72.4
Bone: trabecular tissue density0.10.10.40.20.6-0.60.10.50.4-0.40.4-0.10.10.1
Breakpoint value in progressive ratio session1.11.33.4-1.20.6-0.6-1.50.4-1.8-1.51.5-0.20.2-1.1
Distance traveled before self-admin0.40.41.50.41.2-1.20.50.60.8-0.50.50.0-0.00.3
Distance traveled after self-admin1.21.33.91.80.2-0.21.60.32.01.0-1.1-0.20.11.4
Delta time in closed arm before/after self-admin1.51.53.3-0.7-1.61.6-0.7-1.8-0.71.0-1.01.4-1.4-0.9
Delta time in open arm before/after self-admin1.91.83.21.60.3-0.41.61.51.50.3-0.3-1.81.81.8
Diff in mean of infusions in LGA sessions1.21.33.1-0.41.1-1.2-0.61.4-0.9-1.71.8-1.01.1-0.4
Extinction: sum of active levers before priming0.30.30.7-0.8-0.00.0-0.5-0.3-0.4-0.40.40.6-0.6-0.7
Active lever presses in extinction session 60.40.30.6-0.60.3-0.4-0.20.7-0.6-0.70.8-0.80.8-0.1
Delta distance traveled before/after self-admin1.11.22.61.3-1.11.11.2-0.40.91.6-1.6-0.40.31.1
Delta ambulatory time before/after self-admin0.90.92.01.4-0.70.71.2-0.21.01.3-1.3-0.30.31.1
Time in closed arm before self-admin0.91.12.21.50.7-0.71.11.21.10.0-0.0-1.21.21.2
Time in closed arm after self-admin0.90.92.2-0.61.2-1.2-0.80.8-0.8-1.51.5-0.20.3-0.6
Time in open arm before self-admin1.92.16.0-2.5-0.40.5-1.8-1.2-1.7-0.70.71.5-1.4-1.9
Time in open arm after self-admin0.80.92.10.5-0.90.91.2-0.21.41.3-1.3-0.10.11.0
Sum of active levers in priming session hrs 5-60.20.20.7-0.4-0.80.7-0.2-0.1-0.80.2-0.1-0.50.5-0.2
Time to tail flick, vehicle, before self-admin0.20.20.40.6-0.50.50.4-0.30.50.5-0.60.1-0.10.2
Time to tail flick, vehicle, after self-admin0.80.82.3-0.7-0.70.7-0.9-1.1-1.5-0.10.20.9-0.9-1.4
Time to tail flick, test, before self-admin0.30.30.80.3-0.50.50.0-0.70.50.5-0.50.9-0.9-0.2
Time to tail flick, test, after self-admin1.71.73.9-0.5-1.31.3-0.6-2.0-0.70.6-0.61.9-1.9-1.6
Delta time to tail flick, vehicle, before/after SA0.20.20.9-0.5-0.40.4-0.3-0.3-0.90.1-0.0-0.10.1-0.4
Delta time to tail flick, test, before/after SA0.30.20.5-0.4-0.70.70.1-0.6-0.40.4-0.40.3-0.3-0.4
Ambulatory time before self-admin0.80.83.0-0.21.7-1.70.21.00.8-1.00.9-0.00.10.3
Ambulatory time after self-admin1.31.54.42.00.4-0.31.70.32.11.0-1.1-0.10.11.5
Total heroin consumption0.40.52.2-0.9-0.00.0-0.80.2-1.5-0.60.7-0.50.5-0.6
Area under the delay curve0.30.30.8-0.60.9-0.9-0.40.1-0.1-0.70.60.5-0.5-0.4
Delay disc. indifference point, 0s delay0.40.52.20.30.5-0.40.9-0.11.50.4-0.60.6-0.60.6
Delay disc. indifference point, 16s delay3.53.56.2-2.31.5-1.5-2.40.1-2.2-2.52.51.0-0.9-2.1
Delay disc. indifference point, 2s delay2.22.45.81.9-0.20.22.30.52.41.7-1.7-0.80.82.2
Delay disc. indifference point, 24s delay2.52.44.4-2.00.7-0.7-2.0-0.8-1.7-1.61.51.6-1.6-2.1
Delay disc. indifference point, 4s delay0.70.82.7-0.01.7-1.60.30.90.8-0.90.8-0.00.00.3
Delay disc. indifference point, 8s delay0.20.20.5-0.00.7-0.70.1-0.10.4-0.20.10.7-0.7-0.0
Delay discount exponential model param0.30.30.60.6-0.80.70.40.00.20.6-0.6-0.60.50.4
Delay discount hyperbolic model param0.20.20.60.4-0.80.80.1-0.1-0.10.5-0.4-0.40.40.1
Fecal boli incidents, locomotor time 10.91.02.4-0.3-1.61.6-0.5-1.3-1.30.7-0.70.6-0.6-0.9
Change in fecal boli incidents, locomotor task2.62.55.50.52.2-2.20.72.30.7-1.31.4-1.71.81.3
Time >=10cm from walls, locomotor time 10.50.61.61.00.4-0.31.10.41.30.5-0.6-0.30.30.9
Bouts of movement, locomotor time 11.71.84.3-1.7-0.10.1-1.8-0.6-2.0-1.31.40.9-0.9-2.1
Total resting periods, locomotor time 12.12.35.2-2.0-0.30.3-2.0-1.0-2.2-1.21.21.3-1.2-2.3
Rest time, locomotor task time 11.21.44.0-1.20.1-0.0-1.2-1.4-0.6-0.20.02.0-2.0-1.3
Distance moved, locomotor task time 11.71.94.81.40.2-0.31.41.71.10.2-0.1-2.22.21.7
Vertical activity count, locomotor time 12.72.95.61.91.1-1.12.02.12.40.1-0.0-1.91.92.1
Time >=10cm from walls, locomotor time 21.41.53.91.60.1-0.01.80.22.01.4-1.4-0.40.41.7
Bouts of movement, locomotor time 22.12.37.1-0.0-2.72.60.1-1.7-0.61.9-1.80.4-0.5-0.3
Total resting periods, locomotor time 22.02.26.50.3-2.62.50.3-1.6-0.42.0-1.90.3-0.30.0
Rest time, locomotor task time 20.10.10.40.20.6-0.60.10.40.1-0.20.2-0.20.20.2
Distance moved, locomotor task time 20.30.41.90.60.3-0.30.80.11.40.4-0.40.3-0.30.5
Vertical activity count, locomotor time 20.91.03.10.81.4-1.40.91.21.7-0.50.4-0.40.40.9
Weight adjusted by age0.80.93.30.5-1.81.80.1-0.5-0.51.1-1.0-0.60.60.2
Seeking ratio, delayed vs. immediate footshock0.10.10.20.40.4-0.40.20.40.1-0.20.2-0.30.30.2
Locomotion in novel chamber0.81.03.40.9-0.30.31.01.10.30.3-0.1-1.91.81.1
Locomotion in novel chamber post-restriction0.91.12.2-0.80.4-0.5-0.41.4-0.8-1.31.4-1.41.5-0.1
Progressive ratio0.80.91.9-0.01.1-1.1-0.21.4-0.3-1.11.2-1.11.10.2
Food seeking constrained by brief footshock1.01.22.3-1.10.9-0.9-1.5-0.0-0.9-1.51.50.8-0.8-1.3
Seeking ratio, punishment vs. effort0.50.61.30.1-1.01.10.1-1.20.11.0-1.00.9-0.9-0.2
Run reversals in cocaine runway, females3.83.89.63.10.00.02.70.62.91.9-1.9-0.90.82.6
Run reversals in cocaine runway, males0.30.30.5-0.20.5-0.5-0.7-0.2-0.3-0.60.50.7-0.7-0.6
Latency to leave start box in cocaine runway0.70.81.4-0.11.1-1.1-0.31.2-0.5-1.11.2-1.01.00.1
Latency to leave start box in cocaine runway, F0.10.10.8-0.3-0.40.4-0.4-0.3-0.9-0.10.1-0.00.0-0.4
Latency to leave start box in cocaine runway, M2.12.04.8-0.12.2-2.2-0.21.90.1-1.71.7-1.11.20.4
Cd content in liver3.23.56.9-2.51.2-1.2-2.50.4-2.6-2.52.50.2-0.1-1.9
Co content in liver1.51.83.9-0.81.9-1.9-0.71.5-0.4-2.02.0-0.70.7-0.2
Cu content in liver0.91.02.60.41.0-1.00.61.60.5-0.70.8-1.41.50.9
Fe content in liver1.01.22.8-1.01.6-1.6-0.80.7-0.2-1.71.60.4-0.3-0.8
K content in liver0.10.10.30.1-0.40.40.10.2-0.10.1-0.0-0.50.50.1
Mg content in liver0.70.72.4-0.6-1.61.5-0.5-0.6-1.10.5-0.4-0.20.2-0.5
Mn content in liver0.40.51.00.5-0.90.90.4-0.80.41.0-1.00.4-0.50.1
Na content in liver3.74.08.82.2-2.02.02.3-1.02.12.9-3.0-0.10.01.7
Rb content in liver1.82.34.8-0.81.4-1.5-0.91.9-1.2-2.12.2-1.61.6-0.2
Se content in liver0.10.10.40.3-0.10.10.4-0.20.60.3-0.30.3-0.30.1
Sr content in liver0.40.40.60.7-0.60.60.7-0.00.60.8-0.8-0.40.30.7
Zn content in liver2.02.23.71.7-1.51.51.70.01.21.9-1.8-1.21.11.7