Hub : Genes

ENSRNOG00000069803

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000069803	0.05	0.03	3.6e-04	0.03	0.02	0.03	0.03	9.6e-05	2.1e-03	1.9e-04	2.6e-04
2	Adipose	intron excision ratio	chr1:150700925:150781008	0.12	0.05	3.0e-11	0.06	0.09	0.09	0.09	5.3e-07	6.7e-10	2.9e-10	9.8e-10
3	BLA	intron excision ratio	chr1:150700925:150781008	0.09	0.05	6.0e-04	0.06	0.08	0.09	0.07	6.9e-04	7.3e-05	1.6e-05	9.2e-05
4	Brain	intron excision ratio	chr1:150700925:150781008	0.08	0.04	4.5e-06	0.02	0.06	0.06	0.05	4.9e-03	5.3e-06	1.7e-06	9.4e-06
5	NAcc	intron excision ratio	chr1:150700925:150781008	0.06	0.04	6.1e-04	0.05	0.05	0.05	0.05	8.2e-05	1.4e-04	2.2e-04	1.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
BMI with tail	0.3	1.0	3.4	-0.5	-1.8	0.2	-1.2	0.0
BMI without tail	1.3	2.7	3.6	-1.3	-1.9	1.8	-1.4	1.7
Body weight	0.8	3.6	9.7	-0.9	-3.1	0.5	-2.6	0.4
Epididymis fat weight	0.5	1.3	2.6	-1.0	-0.9	0.5	-1.6	1.3
Glucose	0.6	0.9	1.5	0.7	-0.7	-1.2	-0.7	-1.2
Heart weight	2.3	3.3	4.6	1.8	-1.2	-2.1	-1.9	-1.8
Left kidney weight	1.0	2.8	5.9	1.1	-2.0	-1.3	-2.4	-1.1
Right kidney weight	1.2	3.4	7.6	0.7	-2.4	-1.4	-2.7	-1.1
Tail length	0.8	2.3	5.6	-0.0	-1.9	0.9	-2.4	1.3
Length with tail	0.6	2.0	4.3	-0.7	-2.0	0.8	-2.1	0.9
Length without tail	0.2	0.3	0.7	-0.3	-0.8	-0.5	-0.3	-0.7
Liver weight, left	0.5	0.8	1.1	-1.0	-0.9	0.9	-0.7	0.8
Liver weight, right	1.6	2.6	7.1	-2.7	-0.6	1.4	-0.2	1.9
Parametrial fat weight	0.6	1.2	2.5	-1.3	-0.4	1.6	-0.1	1.3
Retroperitoneal fat weight	1.5	4.9	10.3	-2.0	-3.2	0.4	-3.0	1.0
Intraocular pressure	2.1	3.0	5.4	2.3	-0.7	-1.9	-0.9	-2.2
Extensor digitorum longus weight	0.8	3.0	5.4	0.7	-2.3	-1.5	-2.1	-1.7
Soleus weight	0.2	0.7	2.1	-0.0	-1.5	-0.0	-1.1	-0.4
Tibialis anterior weight	0.2	0.7	2.0	-0.1	-1.4	-0.3	-1.0	-0.5
Tibia length	0.3	0.8	2.7	1.7	1.0	0.2	-0.2	0.4
Number of licking bursts	1.0	1.2	4.7	-2.2	-0.5	0.6	-0.5	0.6
Food consumed during 24 hour testing period	2.1	2.5	4.7	1.3	1.6	1.7	2.2	0.8
Times rat made contact with spout	0.1	0.1	0.3	-0.3	-0.6	0.2	0.4	0.0
Mean time between licks in bursts	1.3	1.8	3.1	1.7	-1.0	-1.8	-1.1	-1.0
Mean num. licks in bursts	1.1	1.3	4.8	2.2	0.2	-0.7	0.6	-0.8
Std. dev. time between licks in bursts	0.1	0.2	0.4	0.2	-0.6	0.0	-0.3	0.4
Water consumed over 24 hours	0.8	1.0	2.5	-1.0	0.3	1.1	1.6	0.4
Indifference point 0 sec	1.4	2.2	3.8	1.4	-1.3	-1.2	-2.0	-1.5
Indifference point AUC	0.3	0.4	0.7	0.8	0.5	0.5	0.5	0.6
Indifference point function ln k	0.6	0.8	2.0	0.4	-0.7	-1.0	-0.7	-1.4
Indifference point function log k	0.6	0.8	2.0	0.4	-0.7	-1.0	-0.7	-1.4
Delay discounting total patch changes 0 sec	1.5	2.5	3.9	1.5	-1.4	-1.3	-2.0	-1.6
Delay discounting total patch changes 12 sec	0.8	1.0	2.4	1.5	-0.5	-1.1	-1.1	-0.4
Delay discounting total patch changes 18 sec	0.9	1.2	4.1	2.0	-0.6	-0.9	-0.8	-0.6
Delay discounting total patch changes 24 sec	0.4	0.5	2.3	1.5	-0.1	-0.4	-0.4	-0.0
Delay discounting total patch changes 6 sec	0.0	0.1	0.2	0.0	-0.3	0.5	-0.0	-0.1
Delay discounting time to switch 0 sec	2.3	3.5	6.5	-2.5	1.3	1.7	1.5	2.0
Delay discounting water rate 0 sec	1.3	2.1	4.6	2.1	-0.4	-1.6	-1.1	-1.4
Delay discounting water rate 12 sec	1.7	2.6	4.9	1.4	-1.4	-1.7	-1.1	-2.2
Delay discounting water rate 18 sec	2.5	3.3	3.8	1.5	-1.9	-1.9	-1.8	-2.0
Delay discounting water rate 24 sec	0.9	1.3	1.9	1.4	-0.8	-1.3	-0.5	-1.4
Delay discounting water rate 6 sec	0.6	0.9	1.6	0.9	-0.3	-1.3	-0.5	-1.2
Locomotor activity	1.7	2.7	5.1	0.8	-2.3	-1.6	-1.5	-1.7
Locomotor testing distance	3.6	6.0	8.0	1.9	-2.7	-2.4	-2.8	-2.3
Locomotor testing rearing	3.0	4.8	8.4	1.1	-2.9	-1.9	-2.8	-1.6
Light reinforcement 1	0.3	0.6	2.1	-1.5	-0.4	0.2	-0.5	0.6
Light reinforcement 2	0.4	0.5	1.1	-1.0	0.8	0.2	-0.0	0.8
Reaction time number correct	0.2	0.3	0.6	-0.3	-0.8	-0.7	-0.2	-0.8
Reaction time mean minus median	1.4	1.8	2.7	0.6	-1.6	-1.4	-1.5	-1.3
Reaction time mean minus median AUC	1.8	2.2	3.7	0.6	-1.6	-1.9	-1.2	-1.8
Reaction time num false alarms	0.7	1.0	2.1	-0.8	0.4	1.5	0.6	1.4
Reaction time num false alarms AUC	0.7	1.0	1.9	-0.3	0.8	1.4	0.8	1.2
Reaction time trials correct on left	0.2	0.3	0.6	-0.3	-0.8	-0.7	-0.2	-0.8
Reaction time trials on left	0.3	0.4	0.6	-0.3	-0.8	-0.7	-0.2	-0.8
Reaction time mean	0.1	0.1	0.5	-0.7	-0.1	-0.0	-0.4	0.3
Reaction time mean AUC	0.2	0.2	0.7	-0.9	0.1	0.2	-0.2	0.5
Median of all reaction times	0.3	0.4	0.7	-0.8	0.6	0.4	0.1	0.8
Reaction time omissions	1.2	1.6	4.2	-0.1	-1.3	-1.2	-2.0	-0.8
Reaction time false alarm rate	0.9	1.2	2.2	-0.3	1.1	1.5	0.8	1.4
Reaction time premature initiation rate	0.2	0.3	0.7	0.3	-0.8	0.3	-0.8	0.4
Reaction time premature initiations	0.2	0.3	0.9	0.3	-1.0	-0.2	-0.8	-0.1
Std. dev. reaction times	1.0	1.3	2.4	0.3	-1.5	-1.1	-1.5	-0.8
Reaction time trials completed	0.3	0.4	0.6	-0.3	-0.8	-0.7	-0.2	-0.8
Reaction time trials AUC	0.3	0.5	0.9	-0.2	-0.9	-0.8	-0.4	-0.8
Social response proportion	1.0	1.1	1.9	-1.4	0.3	1.2	0.5	1.3
Social responses	0.9	1.2	2.5	-0.9	-1.5	-0.4	-1.6	-0.1
Social time	1.1	1.4	2.6	-1.6	0.7	1.2	0.4	1.5
Conditioned locomotion	1.2	1.4	2.7	0.4	-1.2	-1.6	-0.6	-1.6
Cocaine response after cond. corrected	0.2	0.2	0.6	-0.1	0.3	0.2	-0.8	0.5
Cocaine response after cond. not corrected	0.1	0.1	0.3	0.2	0.5	-0.1	-0.5	0.3
Cocaine response before conditioning	0.6	0.7	2.3	-0.2	1.0	0.0	1.5	0.3
Saline control response	2.3	3.0	4.5	1.5	-2.1	-1.7	-1.8	-1.6
Condit. Reinf. active minus inactive responses	5.3	6.6	10.6	2.4	-2.0	-2.8	-3.3	-2.2
Condit. Reinf. active-inactive response ratio	3.1	3.2	4.3	1.7	-1.2	-2.1	-2.1	-1.7
Condit. Reinf. active responses	6.2	8.6	14.2	2.8	-2.5	-3.0	-3.8	-2.4
Condit. Reinf. inactive responses	1.1	1.4	2.5	1.3	-1.5	-0.7	-1.6	-0.5
Condit. Reinf. lever presses	10.0	13.8	16.4	3.9	-2.8	-3.9	-3.7	-4.0
Condit. Reinf. lever reinforcers received	6.6	9.2	14.6	3.0	-2.4	-3.2	-3.8	-2.6
Pavlov. Cond. lever latency	17.6	24.1	30.3	-5.2	3.6	5.5	4.7	5.3
Pavlov. Cond. magazine entry latency	8.0	9.2	13.8	2.8	-1.9	-3.7	-2.8	-3.6
Pavlov. Cond. change in total contacts	10.2	14.3	17.9	3.6	-3.0	-4.2	-3.8	-4.2
Pavlov. Cond. index score	13.9	18.2	23.4	4.5	-2.9	-4.8	-4.1	-4.7
Pavlov. Cond. latency score	12.3	15.5	19.9	4.0	-2.7	-4.5	-3.8	-4.4
Pavlov. Cond. lever contacts	17.4	24.1	30.2	4.9	-3.8	-5.5	-4.9	-5.3
Pavlov. Cond. magazine entry number	12.5	15.3	21.7	-4.3	2.2	4.7	3.3	4.6
Pavlov. Cond. intertrial magazine entries	1.2	1.6	4.0	-0.8	0.2	1.8	0.2	2.0
Pavlov. Cond. lever-magazine prob. diff.	13.3	17.1	21.9	4.3	-2.8	-4.7	-4.1	-4.5
Pavlov. Cond. response bias	18.5	25.6	33.8	5.4	-3.5	-5.8	-4.8	-5.4
Conditioned reinforcement - actives	1.6	1.6	3.9	1.6	2.0	-0.1	1.1	0.3
Conditioned reinforcement - inactives	0.6	0.7	1.0	-0.4	1.0	0.9	0.9	0.8
Conditioned locomotion	1.1	1.3	3.9	0.9	2.0	0.4	1.3	0.5
Intermittent access intake day 1-15 change	0.5	0.5	1.6	1.3	0.7	-0.2	0.3	-0.3
Intermittent access intake escalation	0.6	0.6	2.0	1.4	0.3	-0.7	-0.4	-0.6
Intermittent access intake escalation 2	0.2	0.2	0.3	0.5	0.6	-0.1	-0.3	0.3
Intermitt. access day 1 inactive lever presses	0.7	0.7	1.3	-0.6	0.9	0.7	0.8	1.1
Intermitt. access day 15 inactive lever presses	0.0	0.0	0.0	0.2	-0.2	-0.1	0.0	-0.1
Intermitt. access escalation Index	0.4	0.4	0.7	-0.8	0.2	0.6	0.8	0.4
Intermittent access day 1 total infusions	0.5	0.6	1.4	1.2	-0.2	-0.8	-0.3	-0.8
Intermittent access day 15 total infusions	1.2	1.3	3.4	1.8	0.3	-1.4	-0.4	-1.1
Intermittent access terminal intake (last 3 days)	0.5	0.5	1.6	1.3	0.5	-0.6	-0.2	-0.4
Intermittent access total infusions	0.4	0.4	1.0	1.0	0.9	-0.2	0.4	0.1
Intermittent access day 1 locomotion	0.8	0.8	1.9	0.1	1.4	0.3	1.3	0.5
Intermittent access day 15 total locomotion	0.7	0.8	1.6	1.1	0.0	-1.2	-0.7	-0.8
Intermittent access total locomotion	0.2	0.2	0.5	0.7	0.3	-0.7	-0.2	-0.4
Intermittent access standard deviation	0.3	0.3	0.6	0.1	0.8	0.6	0.5	0.7
Cocaine induced anxiety	0.4	0.5	0.8	-0.9	-0.9	-0.7	-0.6	-0.5
Post-drug Anxiety	0.3	0.4	0.7	-0.0	-0.8	-0.6	-0.6	-0.6
Baseline Anxiety	0.6	0.7	3.1	1.7	0.3	-0.2	0.2	-0.4
Lifetime Intake	0.5	0.6	2.1	1.5	0.7	-0.5	0.1	-0.2
Incentive Sensitization - Responses	1.1	1.1	3.4	1.8	-0.2	-1.2	-0.6	-0.6
Incentive Sensitization - Breakpoint	0.9	0.9	3.1	1.8	-0.0	-1.0	-0.4	-0.5
Progressive ratio test 1 active lever presses	0.5	0.5	0.9	-0.3	0.7	0.7	0.9	0.6
Progressive ratio test 1 breakpoint	0.7	0.7	1.2	-0.4	1.0	0.8	1.1	0.7
Progressive ratio test 1 inactive lever presses	0.2	0.3	0.4	0.5	0.6	0.2	0.7	0.4
Progressive ratio test 2 active lever presses	0.6	0.6	1.9	1.4	0.3	-0.9	-0.4	-0.4
Progressive ratio test 2 breakpoint	0.4	0.4	1.6	1.3	0.3	-0.6	-0.1	-0.2
Progressive ratio test 2 inactive lever presses	0.7	0.9	1.7	1.3	-0.1	-1.3	-0.6	-0.7
Total sessions with >9 infusions	0.5	0.6	2.5	1.6	0.4	-0.5	-0.1	-0.2
Short access day 1 total inactive lever presses	0.4	0.4	1.0	-0.2	0.6	1.0	0.5	0.6
Short access day 10 total inactive lever presses	0.8	0.9	2.2	-1.5	-0.2	1.1	0.5	0.8
Short access day 1 total infusions	0.4	0.5	1.8	1.3	0.7	-0.2	-0.1	0.1
Short access day 10 total infusions	0.6	0.7	2.5	1.6	0.8	0.2	0.3	0.1
Short access total infusions	0.5	0.6	2.1	1.4	0.8	-0.0	0.2	0.2
Short access day 1 locomotion	0.8	0.8	2.2	1.5	0.8	-0.8	0.2	-0.8
Short access day 10 total locomotion	0.1	0.1	0.5	0.7	-0.1	-0.2	0.2	-0.4
Short access total locomotion	0.4	0.4	1.1	0.5	1.0	0.1	0.9	0.3
Compulsive drug intake	2.1	2.1	2.8	-0.5	1.7	1.5	1.6	1.6
One hour access (0.3 mA shock)	1.8	2.1	4.3	2.1	-0.6	-1.8	-1.1	-1.1
One hour access (shock baseline)	2.2	2.6	4.2	1.7	-1.1	-2.0	-1.4	-1.6
Number of responses in last shaping day	0.5	0.5	1.6	-0.3	0.6	0.6	-0.5	1.3
Context. condit. distance diff. score	1.8	2.2	4.8	2.2	0.1	-1.7	-1.0	-1.5
Locomotion velocity, session 1	0.6	0.6	1.5	0.4	1.2	0.2	1.2	-0.0
Locomotion distance, session 1	0.9	1.1	2.2	1.3	-0.2	-1.5	-0.4	-1.3
Locomotion velocity, session 2	0.2	0.2	1.0	1.0	0.4	0.1	0.2	0.1
Locomotion distance, session 2	0.8	1.2	2.0	0.6	-1.3	-1.2	-0.7	-1.4
Locomotion velocity, session 3	0.9	1.1	1.6	0.4	1.2	1.2	1.0	1.0
Locomotion distance, session 3	0.9	1.0	2.4	1.1	1.5	0.7	0.9	0.5
Stereotopy head waving bouts, day 3	1.0	1.3	3.6	-1.9	-0.0	1.0	0.8	1.0
Stereotopy head waving duration, day 3	0.3	0.4	0.7	-0.8	-0.8	-0.3	0.3	-0.8
Locomotion velocity, session 7	0.4	0.4	1.0	0.1	-0.3	-1.0	-0.4	-0.9
Locomotion distance, session 7	1.1	1.5	2.7	0.9	-0.8	-1.6	-1.3	-1.3
Stereotopy head waving bouts, day 7	0.3	0.4	0.9	-0.3	0.8	0.1	1.0	0.2
Stereotopy head waving duration, day 7	0.1	0.1	0.4	0.1	0.5	0.1	0.6	0.1
Locomotion velocity, session 8	1.9	2.3	5.5	2.3	0.2	-1.6	-0.5	-1.8
Locomotion distance, session 8	2.0	2.9	4.6	2.0	-0.8	-2.1	-1.2	-2.0
Degree of sensitization distance	3.2	3.3	5.1	0.1	-2.3	-2.1	-2.2	-1.4
Degree of sensitization stereotypy	0.6	0.7	1.7	0.9	1.3	-0.1	0.9	-0.0
Condit. Reinf. active minus inactive responses	0.5	0.6	1.7	-0.3	-0.0	1.3	-0.1	1.1
Condit. Reinf. active-inactive response ratio	0.4	0.4	1.0	-0.4	-0.2	1.0	-0.1	0.9
Condit. Reinf. active responses	0.3	0.4	1.1	-0.5	0.0	1.0	-0.0	0.8
Condit. Reinf. inactive responses	0.0	0.0	0.1	-0.0	0.2	0.2	0.0	0.2
Incentive salience index mean	0.5	0.6	1.5	0.0	0.5	1.2	0.3	1.0
Condit. Reinf. lever presses	0.3	0.4	0.8	0.8	0.7	0.3	0.9	0.0
Time in familiar zone, hab. session 1	0.0	0.0	0.1	0.2	0.0	-0.2	-0.0	-0.1
Time in novel zone, hab. session 1	0.6	0.6	1.2	-0.6	-1.0	-0.5	-1.1	-0.3
Total zone transitions, hab. session 1	0.2	0.2	0.5	-0.5	-0.2	0.3	0.7	-0.4
Total locomotion distance, hab. session 1	1.9	2.8	5.4	-2.2	0.3	1.8	0.6	2.3
Locomotion velocity, hab. session 1	2.7	3.8	7.6	-2.1	0.9	2.3	1.1	2.8
Time in familiar zone, hab. session 2	1.3	1.3	1.9	1.1	-1.2	-1.3	-0.7	-1.4
Time in novel zone, hab. session 2	0.5	0.5	1.0	-0.2	1.0	0.6	-0.1	1.0
Total zone transitions, hab. session 2	0.1	0.1	0.3	-0.1	-0.4	-0.1	-0.2	-0.5
Total locomotion distance, hab. session 2	1.1	1.4	2.7	-1.6	-0.2	1.3	-0.4	1.7
Locomotion velocity, hab. session 2	1.2	1.6	2.8	-1.7	-0.4	1.4	-0.5	1.6
Novel to familiar place preference ratio	0.5	0.5	1.0	-0.5	0.6	0.8	0.5	1.0
Novelty place preference	0.3	0.3	0.6	-0.3	0.4	0.6	0.3	0.8
Time in novel zone, NPP test	0.0	0.0	0.1	-0.0	0.2	0.2	0.0	0.4
Total zone transitions, NPP test	0.1	0.1	0.6	0.2	0.1	-0.3	0.2	-0.8
Total locomotion distance, NPP test	1.0	1.3	3.0	-1.6	0.6	0.9	-0.1	1.7
Locomotion velocity, NPP test	1.4	2.0	4.3	-1.9	0.7	1.2	0.2	2.1
Pavlov. Cond. lever latency	0.7	0.9	1.9	-0.5	-1.2	-0.8	-1.4	-0.6
Pavlov. Cond. magazine entry latency	0.4	0.5	1.2	0.9	-0.5	-0.4	-1.1	-0.4
Pavlov. Cond. change in total contacts	1.4	1.5	3.6	0.5	1.9	1.1	0.9	1.4
Pavlov. Cond. index score	0.2	0.2	1.1	1.0	0.2	-0.1	-0.2	-0.0
Pavlov. Cond. latency score	0.2	0.2	0.6	0.8	0.5	0.3	0.2	0.3
Pavlov. Cond. lever contacts	0.5	0.6	0.8	0.7	0.9	0.7	0.9	0.6
Pavlov. Cond. magazine entry number	1.0	1.3	1.7	-1.2	0.9	1.2	1.3	1.1
Pavlov. Cond. intertrial magazine entries	1.4	1.7	2.3	-1.1	1.3	1.3	1.5	1.3
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.7	0.8	0.4	0.1	0.1	0.1
Pavlov. Cond. response bias	0.1	0.1	0.6	0.8	0.0	-0.0	-0.2	0.0
Bone: apparent density	0.4	0.6	1.4	-0.4	0.8	0.8	1.2	0.6
Bone surface	0.3	0.6	2.7	1.6	0.4	-0.4	-0.0	-0.3
Bone volume	0.1	0.2	1.1	1.1	0.1	-0.1	0.0	-0.2
Bone: connectivity density	0.8	1.2	2.7	0.5	1.7	0.7	1.5	0.7
Bone: cortical apparent density	1.0	1.3	2.4	-0.7	-1.6	-0.9	-1.0	-1.3
Bone: cortical area	0.5	0.7	1.7	0.7	-0.6	-0.8	-1.3	-0.5
Bone: cortical porosity	0.7	0.8	1.2	-0.6	1.1	0.9	0.7	1.1
Bone: cortical porosity	1.5	1.6	2.5	-0.4	1.6	1.3	1.2	1.5
Bone: cortical thickness	0.1	0.1	0.3	-0.5	-0.1	-0.2	-0.6	0.1
Bone: cortical thickness	1.3	1.5	3.0	1.2	-0.2	-1.7	-1.0	-1.3
Bone: cortical tissue density	0.8	1.0	2.0	-0.7	-1.4	-0.8	-0.8	-1.2
Bone: elastic displacement	0.2	0.2	0.7	-0.8	-0.3	-0.4	-0.0	-0.3
Bone: elastic work	0.1	0.2	0.5	-0.3	0.1	-0.2	0.7	-0.5
Bone: endosteal estimation	0.3	0.6	2.3	1.5	-0.1	-0.2	-0.6	0.0
Bone: endosteal perimeter	1.0	2.0	4.8	2.2	-0.9	-1.2	-1.2	-1.2
Bone: final force	0.3	0.4	0.9	0.3	-0.3	-0.9	-0.6	-0.9
Bone: final moment	0.3	0.5	1.1	0.5	-0.4	-1.0	-0.6	-0.9
Bone: marrow area	0.2	0.5	2.0	1.4	-0.1	-0.2	-0.6	0.0
Bone: maximum diameter	0.9	1.7	2.7	1.7	-0.9	-1.1	-1.5	-1.2
Bone: maximum force	0.1	0.3	0.5	0.6	0.1	-0.6	-0.1	-0.7
Bone: maximum moment	0.2	0.3	0.5	0.7	0.1	-0.6	-0.1	-0.7
Bone: minimum diameter	0.2	0.3	1.0	1.0	-0.3	-0.0	-0.6	0.1
Bone: periosteal estimation	0.5	1.0	2.8	1.7	-0.3	-0.7	-1.3	-0.4
Bone: periosteal perimeter	1.6	2.6	2.9	1.5	-1.7	-1.5	-1.7	-1.7
Bone: post-yield work	0.7	1.0	1.6	-0.3	1.2	1.3	1.0	0.8
Bone: stiffness	0.1	0.1	0.3	-0.5	-0.0	-0.2	-0.3	-0.2
Bone: tissue strength	2.5	2.4	3.9	-2.0	1.5	1.5	1.6	1.2
Bone: trabecular number	0.4	0.7	1.6	-0.7	0.9	0.6	1.3	0.3
Bone: trabecular spacing	0.3	0.3	0.8	0.7	0.1	-0.9	-0.5	-0.3
Bone: trabecular thickness	0.6	0.7	2.5	-0.1	-1.6	-0.2	-0.6	-0.8
Bone: trabecular tissue density	1.8	2.5	6.1	-1.3	-2.5	-0.7	-1.9	-0.7
Breakpoint value in progressive ratio session	0.0	0.0	0.1	-0.2	0.3	0.0	0.0	-0.1
Distance traveled before self-admin	0.7	0.7	1.5	-0.7	0.6	1.2	0.8	0.7
Distance traveled after self-admin	3.5	3.8	6.5	-1.7	1.2	2.5	2.4	1.6
Delta time in closed arm before/after self-admin	8.4	8.1	13.4	1.4	-3.7	-2.8	-3.0	-2.9
Delta time in open arm before/after self-admin	0.9	0.8	1.4	0.4	1.2	1.0	0.9	1.0
Diff in mean of infusions in LGA sessions	0.9	1.1	4.5	-2.1	-0.4	0.7	0.2	0.3
Extinction: sum of active levers before priming	0.4	0.4	0.9	0.2	-0.7	-0.6	-0.9	-0.4
Active lever presses in extinction session 6	0.1	0.1	0.2	0.4	0.4	-0.2	0.1	-0.2
Delta distance traveled before/after self-admin	0.3	0.4	0.8	-0.7	-0.4	0.6	0.9	0.2
Delta ambulatory time before/after self-admin	0.3	0.3	0.5	-0.3	-0.7	-0.1	0.7	-0.5
Time in closed arm before self-admin	0.2	0.2	0.9	0.2	0.5	0.0	0.9	-0.1
Time in closed arm after self-admin	0.8	0.8	1.9	0.9	-0.5	-1.0	0.2	-1.4
Time in open arm before self-admin	0.4	0.5	0.8	-0.7	-0.8	-0.6	-0.9	-0.4
Time in open arm after self-admin	0.3	0.3	0.7	-0.3	0.3	0.8	0.2	0.8
Sum of active levers in priming session hrs 5-6	0.3	0.3	0.7	-0.8	-0.6	0.2	-0.5	-0.1
Time to tail flick, vehicle, before self-admin	0.4	0.5	0.9	-0.2	-1.0	-0.7	-0.8	-0.5
Time to tail flick, vehicle, after self-admin	2.4	2.5	3.9	2.0	-1.2	-1.8	-0.9	-1.9
Time to tail flick, test, before self-admin	0.3	0.3	0.8	0.9	0.5	0.6	0.5	0.2
Time to tail flick, test, after self-admin	3.0	3.1	3.6	1.8	-1.7	-1.9	-1.9	-1.6
Delta time to tail flick, vehicle, before/after SA	1.1	1.1	2.2	1.5	-0.0	-1.2	-0.3	-1.3
Delta time to tail flick, test, before/after SA	0.8	0.7	1.1	-0.2	-0.9	-1.0	-1.0	-0.7
Ambulatory time before self-admin	1.2	1.3	2.1	-0.7	1.1	1.5	1.3	1.0
Ambulatory time after self-admin	3.3	3.7	7.3	-1.5	1.3	2.3	2.7	1.4
Total heroin consumption	1.2	1.4	2.3	0.2	-1.4	-1.3	-1.1	-1.5
Area under the delay curve	0.1	0.2	0.4	0.6	-0.0	-0.1	0.1	-0.6
Delay disc. indifference point, 0s delay	0.5	0.5	1.3	1.2	-0.2	-0.7	-0.6	-0.4
Delay disc. indifference point, 16s delay	1.7	1.7	3.7	0.7	-1.5	-1.2	-0.7	-1.9
Delay disc. indifference point, 2s delay	0.2	0.2	0.6	0.8	0.6	0.3	0.2	0.1
Delay disc. indifference point, 24s delay	0.2	0.2	0.4	-0.4	-0.4	-0.1	0.0	-0.7
Delay disc. indifference point, 4s delay	0.2	0.2	0.9	0.9	0.0	0.3	-0.1	-0.2
Delay disc. indifference point, 8s delay	0.2	0.2	0.6	0.8	-0.0	-0.2	0.1	-0.6
Delay discount exponential model param	0.1	0.1	0.4	-0.5	0.0	0.1	-0.1	0.7
Delay discount hyperbolic model param	0.1	0.1	0.4	-0.6	-0.1	-0.0	-0.1	0.5
Fecal boli incidents, locomotor time 1	1.8	2.0	6.4	2.5	1.3	-1.2	-0.7	-0.2
Change in fecal boli incidents, locomotor task	0.8	0.8	2.9	-1.7	-0.8	0.2	0.4	-0.2
Time >=10cm from walls, locomotor time 1	0.7	0.7	1.4	0.8	1.2	0.1	1.2	0.3
Bouts of movement, locomotor time 1	0.7	0.8	1.6	0.8	-1.3	-0.3	-0.6	-1.1
Total resting periods, locomotor time 1	0.4	0.5	1.0	0.7	-0.9	-0.2	-0.2	-1.0
Rest time, locomotor task time 1	0.2	0.2	0.5	0.5	-0.2	-0.5	0.3	-0.7
Distance moved, locomotor task time 1	0.2	0.3	1.0	0.2	-0.4	-0.1	-1.0	0.1
Vertical activity count, locomotor time 1	0.5	0.5	1.4	0.3	-0.7	-0.5	-1.2	-0.3
Time >=10cm from walls, locomotor time 2	0.9	1.0	1.4	1.1	1.2	0.7	0.8	1.0
Bouts of movement, locomotor time 2	0.1	0.1	0.4	0.6	-0.2	0.4	0.3	0.0
Total resting periods, locomotor time 2	0.1	0.1	0.4	0.6	-0.1	0.3	0.3	-0.0
Rest time, locomotor task time 2	0.5	0.6	1.3	-1.1	0.6	0.6	0.6	0.7
Distance moved, locomotor task time 2	0.6	0.7	1.8	1.3	-0.3	-0.5	-1.1	-0.3
Vertical activity count, locomotor time 2	0.9	0.9	2.7	1.0	-0.6	-0.8	-1.7	-0.2
Weight adjusted by age	0.2	0.2	0.5	-0.1	0.2	0.4	-0.5	0.7
Seeking ratio, delayed vs. immediate footshock	1.2	1.4	2.1	-0.7	1.4	1.3	1.1	1.4
Locomotion in novel chamber	0.5	0.7	2.3	0.4	1.5	0.2	1.0	-0.1
Locomotion in novel chamber post-restriction	1.5	1.8	3.5	1.9	0.5	-1.6	0.1	-1.6
Progressive ratio	0.4	0.4	1.6	1.3	0.3	-0.2	0.1	-0.5
Food seeking constrained by brief footshock	1.3	1.6	3.7	1.2	-1.4	-0.9	-1.9	-0.5
Seeking ratio, punishment vs. effort	0.4	0.5	1.5	-0.6	-0.2	0.5	-0.6	1.2
Run reversals in cocaine runway, females	0.6	0.6	1.8	0.4	-1.3	0.0	-1.1	-0.0
Run reversals in cocaine runway, males	3.3	3.2	6.5	1.4	-1.5	-2.0	-1.1	-2.6
Latency to leave start box in cocaine runway	3.1	3.4	4.8	-2.0	1.5	2.2	1.2	2.2
Latency to leave start box in cocaine runway, F	1.7	1.9	3.3	-1.3	1.2	1.7	0.4	1.8
Latency to leave start box in cocaine runway, M	3.1	3.0	3.5	-1.7	1.6	1.8	1.9	1.7
Cd content in liver	0.2	0.2	0.3	-0.2	-0.6	-0.5	-0.4	-0.4
Co content in liver	2.2	2.6	4.0	1.9	-1.0	-2.0	-1.2	-1.7
Cu content in liver	1.7	2.1	3.1	1.2	-1.7	-1.4	-1.8	-1.0
Fe content in liver	0.3	0.3	0.7	0.2	0.8	-0.1	-0.8	0.4
K content in liver	1.9	1.9	3.3	-1.2	0.9	1.8	1.1	1.7
Mg content in liver	0.6	0.7	1.6	-0.1	0.7	1.3	0.4	1.1
Mn content in liver	1.4	1.6	2.3	-0.9	1.5	1.3	1.4	1.2
Na content in liver	4.1	4.3	6.5	-1.0	2.6	2.1	1.9	2.5
Rb content in liver	1.0	1.3	2.2	0.6	-1.5	-0.9	-1.1	-1.4
Se content in liver	4.2	5.1	6.9	-1.4	2.3	2.4	2.3	2.6
Sr content in liver	0.3	0.3	1.4	1.2	0.3	-0.1	0.3	-0.2
Zn content in liver	1.7	1.9	2.6	1.5	-1.0	-1.6	-1.6	-1.1