Hub : Genes

ENSRNOG00000069740

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000069740	0.07	0.04	5.2e-06	0.02	0.03	0.02	0.02	9.7e-04	3.2e-04	1.1e-03	1.4e-03
2	Adipose	isoform ratio	ENSRNOT00000120115	0.04	0.03	2.6e-04	0.01	0.03	0.02	0.02	5.0e-02	5.6e-04	2.6e-03	6.5e-03
3	Adipose	intron excision ratio	chr5:149272618:149283575	0.02	0.02	4.1e-03	0.01	0	0	0	1.7e-02	2.0e-01	1.6e-01	1.1e-01
4	Brain	intron excision ratio	chr5:149272618:149283575	0.02	0.01	8.7e-03	0.02	0.01	0.01	0.01	7.5e-03	3.5e-02	1.7e-02	2.0e-02
5	Liver	intron excision ratio	chr5:149272618:149283575	0.04	0.03	2.9e-04	0.02	0.01	0.01	0.01	4.7e-03	6.8e-03	2.1e-02	8.5e-03
6	PL	gene expression	ENSRNOG00000069740	0.05	0.04	1.2e-03	0.04	0.03	0.04	0.04	2.6e-04	1.4e-03	4.1e-04	4.7e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	0.7	2.2	7.1	-1.1	-0.3	2.7	0.9	1.6	-1.2
BMI without tail	0.7	1.5	3.9	-0.7	-1.0	2.0	0.5	1.5	-1.0
Body weight	2.2	9.4	19.4	-1.0	-3.4	4.4	2.6	3.3	-2.7
Epididymis fat weight	0.1	0.1	0.6	-0.0	0.1	0.8	-0.2	0.1	0.3
Glucose	1.3	2.0	7.5	2.7	-1.2	0.1	-1.0	-0.6	1.2
Heart weight	0.4	0.5	1.7	1.3	-1.0	0.4	-0.1	-0.1	-0.3
Left kidney weight	3.7	10.6	27.8	0.7	-5.3	3.8	2.4	2.8	-2.7
Right kidney weight	1.3	3.6	12.6	1.3	-3.6	1.7	1.1	1.2	-1.4
Tail length	0.6	1.7	6.2	0.5	-2.5	1.2	0.6	1.2	-0.7
Length with tail	1.1	3.9	11.2	0.7	-3.3	2.1	1.7	1.6	-1.4
Length without tail	1.3	2.8	4.4	-0.2	-2.0	2.1	2.0	1.4	-1.6
Liver weight, left	1.9	3.1	6.2	-0.4	-2.5	2.4	1.0	1.9	-1.2
Liver weight, right	1.9	3.1	5.2	-0.6	-2.3	1.9	1.6	1.9	-1.7
Parametrial fat weight	0.9	1.7	3.3	1.2	0.8	-0.8	-1.8	-1.4	1.5
Retroperitoneal fat weight	0.3	1.0	2.1	0.4	1.4	-0.2	-1.0	-1.1	1.2
Intraocular pressure	1.5	2.1	3.8	-1.4	-0.8	0.7	2.0	1.4	-1.9
Extensor digitorum longus weight	0.8	3.1	6.6	-2.6	0.1	1.7	1.5	1.8	-1.9
Soleus weight	4.0	11.8	19.4	-4.4	-0.7	3.5	3.7	3.6	-3.4
Tibialis anterior weight	2.3	7.9	11.6	-3.4	-0.7	2.9	3.0	2.8	-3.1
Tibia length	0.9	2.6	3.5	-1.1	-1.6	1.9	1.5	1.8	-1.6
Number of licking bursts	0.2	0.3	0.5	0.7	0.2	-0.4	-0.5	-0.5	0.6
Food consumed during 24 hour testing period	0.3	0.3	1.1	1.0	-0.7	-0.2	-0.3	0.1	0.3
Times rat made contact with spout	0.5	0.5	1.9	0.9	-0.3	-1.4	-0.0	-0.6	0.1
Mean time between licks in bursts	0.2	0.3	0.9	-0.9	0.7	0.7	-0.2	0.2	-0.2
Mean num. licks in bursts	0.2	0.2	0.4	0.2	-0.6	-0.6	0.4	-0.0	-0.5
Std. dev. time between licks in bursts	1.3	1.6	2.8	-1.6	-0.3	0.9	1.4	1.1	-1.7
Water consumed over 24 hours	0.3	0.4	1.1	0.5	0.3	-1.0	-0.6	-0.6	0.5
Indifference point 0 sec	1.3	2.1	4.1	-1.6	-0.9	0.7	1.7	1.4	-2.0
Indifference point AUC	1.6	1.9	2.9	-0.8	-1.5	1.1	1.4	1.7	-1.5
Indifference point function ln k	1.7	2.4	6.3	-0.5	2.5	-1.2	-1.4	-1.5	1.4
Indifference point function log k	1.7	2.4	6.3	-0.5	2.5	-1.2	-1.4	-1.5	1.4
Delay discounting total patch changes 0 sec	1.2	2.0	3.7	-1.7	-0.7	0.6	1.7	1.3	-1.9
Delay discounting total patch changes 12 sec	2.1	2.9	4.5	-1.0	-2.0	1.0	1.7	1.9	-2.1
Delay discounting total patch changes 18 sec	2.4	3.2	5.0	-1.4	-1.9	1.0	1.9	2.2	-2.1
Delay discounting total patch changes 24 sec	2.3	2.9	4.8	-1.3	-1.6	1.1	1.9	2.0	-2.2
Delay discounting total patch changes 6 sec	3.1	4.8	7.7	-0.9	-2.5	1.2	2.6	2.3	-2.8
Delay discounting time to switch 0 sec	0.7	1.0	3.1	1.8	-0.9	-1.1	-0.2	-0.9	0.5
Delay discounting water rate 0 sec	0.4	0.7	2.3	-1.1	1.5	-0.3	-0.6	-0.1	0.4
Delay discounting water rate 12 sec	0.8	1.1	3.9	-2.0	1.2	0.3	0.7	0.7	-0.6
Delay discounting water rate 18 sec	1.4	1.9	6.1	-2.5	0.4	1.5	0.8	1.2	-0.8
Delay discounting water rate 24 sec	0.9	1.2	3.0	-0.6	1.7	-0.6	-1.4	-0.5	1.2
Delay discounting water rate 6 sec	0.9	1.3	4.3	-1.0	2.1	-0.8	-0.8	-0.5	0.9
Locomotor activity	5.2	8.3	12.1	-2.4	-2.2	3.5	2.8	3.1	-3.1
Locomotor testing distance	2.8	4.7	6.7	-1.8	-1.6	2.6	2.1	2.4	-2.3
Locomotor testing rearing	4.1	6.4	8.3	-2.2	-1.8	2.6	2.7	2.9	-2.8
Light reinforcement 1	0.9	1.6	2.4	-1.0	-1.0	1.1	1.5	1.4	-1.6
Light reinforcement 2	0.4	0.6	1.0	-0.8	0.0	0.7	1.0	0.9	-0.6
Reaction time number correct	0.8	1.2	1.7	0.4	1.3	-0.8	-1.2	-1.3	1.3
Reaction time mean minus median	0.3	0.4	0.8	0.4	-0.9	0.9	0.3	0.6	-0.4
Reaction time mean minus median AUC	0.5	0.7	1.9	0.8	-1.4	0.8	0.3	0.7	-0.5
Reaction time num false alarms	0.4	0.5	1.0	-0.6	-0.4	1.0	0.7	0.6	-0.8
Reaction time num false alarms AUC	0.3	0.5	1.1	-0.8	-0.1	1.1	0.6	0.5	-0.7
Reaction time trials correct on left	0.8	1.2	1.7	0.4	1.3	-0.8	-1.2	-1.3	1.3
Reaction time trials on left	0.8	1.2	1.8	0.4	1.3	-0.8	-1.2	-1.3	1.3
Reaction time mean	0.2	0.2	0.5	-0.2	-0.6	0.5	0.3	0.7	-0.4
Reaction time mean AUC	0.0	0.0	0.1	0.0	-0.1	0.1	-0.1	0.3	0.0
Median of all reaction times	0.0	0.0	0.2	-0.2	-0.1	0.2	-0.1	0.4	-0.0
Reaction time omissions	0.0	0.0	0.1	-0.3	-0.0	0.4	0.1	0.3	-0.0
Reaction time false alarm rate	0.7	0.9	1.6	-0.8	-0.6	1.3	0.9	0.9	-1.1
Reaction time premature initiation rate	0.6	0.8	2.5	-0.1	1.1	-1.6	-0.3	-1.0	0.2
Reaction time premature initiations	1.0	1.4	3.2	-0.0	1.6	-1.8	-0.6	-1.4	0.6
Std. dev. reaction times	0.2	0.2	0.4	0.0	-0.6	0.5	0.4	0.6	-0.5
Reaction time trials completed	0.8	1.2	1.8	0.4	1.3	-0.8	-1.2	-1.3	1.3
Reaction time trials AUC	0.7	1.0	1.5	0.4	1.1	-0.6	-1.2	-1.2	1.2
Social response proportion	0.8	0.8	2.3	1.0	0.4	-0.5	-0.9	-1.5	0.7
Social responses	1.7	2.2	3.6	-1.3	-0.8	1.9	1.6	1.4	-1.6
Social time	0.1	0.1	0.2	-0.5	0.3	0.5	0.1	-0.1	-0.1
Conditioned locomotion	1.9	2.2	4.1	0.5	1.7	-1.4	-2.0	-1.2	1.6
Cocaine response after cond. corrected	4.6	5.2	6.4	2.5	1.3	-2.2	-2.4	-2.5	2.5
Cocaine response after cond. not corrected	3.7	4.1	5.8	2.4	0.8	-2.2	-2.0	-2.2	2.1
Cocaine response before conditioning	1.3	1.6	3.1	-0.6	-1.8	0.9	1.5	1.3	-1.3
Saline control response	0.1	0.1	0.3	-0.2	0.3	-0.5	0.1	0.1	-0.2
Condit. Reinf. active minus inactive responses	0.9	1.1	1.9	-1.4	0.1	1.3	0.9	1.2	-0.8
Condit. Reinf. active-inactive response ratio	1.2	1.2	2.0	0.6	1.4	-0.6	-1.1	-1.2	1.4
Condit. Reinf. active responses	4.9	6.8	9.7	-2.9	-1.2	2.8	2.5	3.1	-2.7
Condit. Reinf. inactive responses	9.9	12.3	17.3	-3.5	-2.6	3.4	3.5	4.2	-3.8
Condit. Reinf. lever presses	3.9	5.3	10.4	-3.2	-0.5	1.7	2.6	2.4	-2.5
Condit. Reinf. lever reinforcers received	4.7	6.6	9.4	-2.9	-1.2	2.6	2.6	3.1	-2.6
Pavlov. Cond. lever latency	2.4	3.3	5.8	2.4	0.6	-1.0	-2.1	-2.2	1.9
Pavlov. Cond. magazine entry latency	0.4	0.4	1.3	-1.0	1.1	-0.1	-0.1	0.1	0.5
Pavlov. Cond. change in total contacts	2.3	3.2	5.9	-2.4	-0.5	1.5	2.0	1.9	-1.8
Pavlov. Cond. index score	1.2	1.5	4.5	-2.1	0.3	0.5	1.2	1.4	-1.0
Pavlov. Cond. latency score	1.0	1.2	3.9	-2.0	0.5	0.2	1.1	1.2	-0.8
Pavlov. Cond. lever contacts	2.6	3.6	5.5	-2.3	-0.9	1.3	2.1	2.3	-2.0
Pavlov. Cond. magazine entry number	0.4	0.5	1.2	1.1	-0.1	-0.5	-0.8	-1.0	0.4
Pavlov. Cond. intertrial magazine entries	1.8	2.4	4.5	1.9	0.3	-1.1	-2.1	-1.4	1.7
Pavlov. Cond. lever-magazine prob. diff.	1.3	1.7	5.0	-2.2	0.3	0.5	1.2	1.5	-1.0
Pavlov. Cond. response bias	1.9	2.6	5.2	-2.3	-0.3	1.2	1.6	2.0	-1.5
Conditioned reinforcement - actives	0.4	0.4	1.0	-0.3	-0.7	1.0	0.9	0.3	-0.4
Conditioned reinforcement - inactives	0.9	1.0	1.9	-0.9	-0.9	0.8	1.2	0.6	-1.4
Conditioned locomotion	0.7	0.9	1.6	-0.1	-1.2	1.0	1.2	0.7	-0.9
Intermittent access intake day 1-15 change	2.6	2.6	5.0	-2.2	-0.2	2.0	1.5	1.5	-1.4
Intermittent access intake escalation	1.5	1.4	2.8	-1.7	-0.2	1.6	1.0	1.2	-0.9
Intermittent access intake escalation 2	0.6	0.6	1.5	-1.2	-0.1	0.8	0.6	0.9	-0.4
Intermitt. access day 1 inactive lever presses	3.5	3.7	6.3	-0.8	-2.5	2.0	1.7	1.9	-2.3
Intermitt. access day 15 inactive lever presses	1.2	1.4	2.7	-0.5	-1.7	1.2	1.1	1.0	-1.3
Intermitt. access escalation Index	1.8	1.6	2.9	-1.2	-0.7	0.9	1.7	1.3	-1.5
Intermittent access day 1 total infusions	1.5	1.8	5.5	0.6	-2.3	0.5	1.3	1.1	-1.3
Intermittent access day 15 total infusions	2.9	3.2	4.7	-0.9	-2.2	1.7	2.1	1.8	-1.8
Intermittent access terminal intake (last 3 days)	2.2	2.4	3.7	-0.9	-1.9	1.2	1.8	1.7	-1.5
Intermittent access total infusions	1.6	1.8	4.2	-0.2	-2.0	0.9	1.6	1.1	-1.4
Intermittent access day 1 locomotion	0.2	0.2	0.4	-0.4	-0.2	-0.0	0.6	0.2	-0.6
Intermittent access day 15 total locomotion	0.1	0.2	0.7	-0.3	0.1	-0.8	0.4	-0.1	-0.2
Intermittent access total locomotion	0.7	0.8	1.7	-0.8	-0.7	0.0	1.3	0.7	-1.2
Intermittent access standard deviation	3.6	3.8	6.0	-1.3	-1.7	2.4	2.1	1.9	-2.0
Cocaine induced anxiety	0.2	0.3	0.6	0.7	-0.1	0.0	-0.6	-0.8	0.3
Post-drug Anxiety	0.6	0.7	1.9	-0.2	1.4	-0.6	-1.0	-0.8	0.6
Baseline Anxiety	0.9	0.9	2.7	-1.5	1.6	-0.0	0.1	0.6	-0.3
Lifetime Intake	1.1	1.2	3.3	0.0	-1.8	0.6	1.4	0.8	-1.1
Incentive Sensitization - Responses	2.2	2.2	5.5	-0.1	-2.3	1.0	1.7	1.3	-1.4
Incentive Sensitization - Breakpoint	2.0	2.0	5.2	-0.1	-2.3	1.0	1.6	1.2	-1.3
Progressive ratio test 1 active lever presses	0.5	0.5	1.2	0.1	-1.1	0.0	0.9	0.5	-0.7
Progressive ratio test 1 breakpoint	0.6	0.6	1.3	-0.1	-1.1	0.1	1.2	0.6	-0.9
Progressive ratio test 1 inactive lever presses	0.6	0.6	1.2	-0.1	-1.1	0.7	0.9	0.3	-1.0
Progressive ratio test 2 active lever presses	1.3	1.4	3.8	0.0	-2.0	0.5	1.6	0.8	-1.1
Progressive ratio test 2 breakpoint	1.3	1.5	4.2	0.1	-2.1	0.5	1.6	0.7	-1.1
Progressive ratio test 2 inactive lever presses	1.7	2.0	5.6	0.3	-2.4	0.8	1.7	0.7	-1.5
Total sessions with >9 infusions	1.4	1.6	2.3	-0.8	-1.3	1.3	1.5	0.9	-1.4
Short access day 1 total inactive lever presses	0.8	0.9	1.7	-1.3	-0.2	0.5	1.2	0.4	-1.3
Short access day 10 total inactive lever presses	3.1	3.4	4.9	-1.2	-1.8	2.2	1.7	1.8	-2.2
Short access day 1 total infusions	1.4	1.5	2.8	-0.4	-1.7	0.8	1.7	0.8	-1.4
Short access day 10 total infusions	0.6	0.7	2.1	0.5	-1.5	0.2	1.1	0.4	-0.7
Short access total infusions	0.4	0.5	1.5	0.3	-1.2	0.0	0.9	0.1	-0.7
Short access day 1 locomotion	0.2	0.2	0.4	-0.5	0.2	0.5	0.6	-0.3	-0.4
Short access day 10 total locomotion	1.6	1.8	2.6	-0.9	-1.1	1.6	1.4	1.2	-1.6
Short access total locomotion	0.6	0.6	1.2	-0.5	-0.4	1.1	0.9	0.2	-0.9
Compulsive drug intake	1.4	1.4	2.8	-0.5	-1.5	1.7	0.9	1.2	-1.0
One hour access (0.3 mA shock)	3.7	4.3	5.8	-1.4	-2.1	2.0	2.4	2.1	-2.2
One hour access (shock baseline)	1.8	2.0	4.0	-1.1	-1.2	0.8	2.0	1.4	-1.7
Number of responses in last shaping day	0.2	0.2	0.7	-0.0	-0.3	0.3	0.8	0.1	-0.5
Context. condit. distance diff. score	1.7	2.1	3.1	-1.0	-1.3	1.1	1.7	1.8	-1.6
Locomotion velocity, session 1	1.6	1.8	5.9	-2.4	0.6	0.9	0.6	1.3	-1.2
Locomotion distance, session 1	1.2	1.5	5.2	-2.3	1.0	0.1	1.1	0.7	-1.2
Locomotion velocity, session 2	2.1	2.4	4.9	-0.1	2.2	-1.7	-1.4	-1.7	1.3
Locomotion distance, session 2	1.6	2.3	6.2	-2.5	0.2	1.1	1.3	1.4	-1.6
Locomotion velocity, session 3	0.3	0.4	1.3	-0.8	1.1	-0.4	-0.1	0.0	0.2
Locomotion distance, session 3	3.2	3.5	5.5	-1.6	-1.4	1.2	2.3	2.1	-2.3
Stereotopy head waving bouts, day 3	1.0	1.2	1.9	0.3	1.3	-0.9	-1.2	-1.2	1.4
Stereotopy head waving duration, day 3	2.3	2.7	4.4	1.3	1.3	-1.3	-1.9	-1.8	2.1
Locomotion velocity, session 7	2.5	2.7	4.3	-0.8	-2.0	1.4	1.7	2.1	-1.7
Locomotion distance, session 7	0.4	0.5	0.8	-0.3	-0.8	0.6	0.7	0.9	-0.7
Stereotopy head waving bouts, day 7	0.1	0.1	0.2	0.5	-0.0	-0.0	-0.3	-0.3	0.3
Stereotopy head waving duration, day 7	0.1	0.1	0.2	0.4	-0.2	0.3	-0.3	-0.2	0.3
Locomotion velocity, session 8	0.4	0.5	1.8	-1.3	0.8	0.5	0.2	0.5	-0.3
Locomotion distance, session 8	3.1	4.7	6.2	-2.5	-0.9	1.7	2.4	2.5	-2.5
Degree of sensitization distance	3.5	3.6	5.8	1.7	1.2	-1.4	-2.4	-1.9	2.4
Degree of sensitization stereotypy	0.4	0.4	1.2	0.5	-1.1	0.7	0.4	0.5	-0.4
Condit. Reinf. active minus inactive responses	1.4	1.5	2.1	1.0	0.9	-1.3	-1.5	-1.3	1.3
Condit. Reinf. active-inactive response ratio	1.9	2.0	3.5	1.4	0.7	-1.0	-1.9	-1.5	1.7
Condit. Reinf. active responses	0.2	0.3	1.0	0.1	0.3	-1.0	-0.4	-0.5	0.4
Condit. Reinf. inactive responses	1.0	1.1	2.0	-1.4	-0.5	-0.0	1.4	1.1	-1.3
Incentive salience index mean	0.3	0.4	1.1	0.2	0.3	-1.1	-0.6	-0.6	0.5
Condit. Reinf. lever presses	0.4	0.6	1.1	-1.0	-0.5	-0.3	0.9	0.7	-1.0
Time in familiar zone, hab. session 1	0.3	0.3	0.9	0.7	-0.9	-0.2	0.4	0.3	-0.3
Time in novel zone, hab. session 1	0.1	0.1	0.3	0.3	0.4	-0.0	-0.3	-0.4	0.5
Total zone transitions, hab. session 1	0.8	1.2	2.3	-1.5	-0.2	0.6	1.4	0.9	-1.3
Total locomotion distance, hab. session 1	1.0	1.4	3.0	-1.7	-0.3	0.5	1.5	0.9	-1.5
Locomotion velocity, hab. session 1	0.8	1.1	3.1	-1.8	0.1	0.3	1.2	0.6	-1.4
Time in familiar zone, hab. session 2	0.2	0.3	0.4	-0.0	-0.6	-0.6	0.6	0.4	-0.5
Time in novel zone, hab. session 2	0.6	0.6	1.0	0.3	1.0	0.0	-1.0	-0.7	0.9
Total zone transitions, hab. session 2	2.6	3.4	8.9	-3.0	0.3	1.2	1.8	1.9	-1.8
Total locomotion distance, hab. session 2	1.8	2.4	7.2	-2.7	0.6	0.5	1.5	1.3	-1.6
Locomotion velocity, hab. session 2	2.3	3.2	8.5	-2.9	0.3	1.0	1.8	1.6	-2.0
Novel to familiar place preference ratio	1.1	1.2	3.1	1.8	-0.3	-0.3	-1.2	-1.0	1.1
Novelty place preference	1.0	1.0	2.9	1.7	-0.6	-0.2	-1.1	-0.8	1.0
Time in novel zone, NPP test	1.1	1.2	3.5	1.9	-0.7	-0.2	-1.2	-0.8	1.0
Total zone transitions, NPP test	1.1	1.6	4.8	-2.2	0.6	0.5	1.2	1.1	-1.2
Total locomotion distance, NPP test	0.9	1.2	4.0	-2.0	0.5	0.1	0.9	0.9	-1.1
Locomotion velocity, NPP test	1.1	1.6	5.6	-2.4	0.6	0.1	1.1	0.9	-1.3
Pavlov. Cond. lever latency	0.5	0.7	2.8	1.7	-0.6	0.0	-0.5	-0.4	0.8
Pavlov. Cond. magazine entry latency	0.3	0.4	0.7	-0.7	-0.4	0.3	0.8	0.6	-0.8
Pavlov. Cond. change in total contacts	0.4	0.4	1.6	-1.3	0.7	-0.2	0.4	0.1	-0.5
Pavlov. Cond. index score	0.5	0.7	1.8	-1.3	-0.0	0.4	0.8	0.6	-0.9
Pavlov. Cond. latency score	0.5	0.6	2.0	-1.4	0.1	0.2	0.7	0.5	-0.9
Pavlov. Cond. lever contacts	0.7	0.8	3.5	-1.9	1.0	-0.1	0.3	0.3	-0.5
Pavlov. Cond. magazine entry number	1.9	2.3	3.4	1.3	1.4	-1.2	-1.7	-1.6	1.8
Pavlov. Cond. intertrial magazine entries	7.6	9.1	12.4	2.1	2.6	-3.4	-3.5	-3.0	3.3
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.3	1.2	-1.1	0.3	0.2	0.4	0.3	-0.5
Pavlov. Cond. response bias	1.0	1.2	2.9	-1.7	-0.3	0.6	1.1	1.1	-1.3
Bone: apparent density	1.6	2.7	4.6	-2.1	-0.6	1.5	1.6	1.8	-1.8
Bone surface	1.5	2.7	3.9	-2.0	-0.7	1.7	1.4	1.9	-1.7
Bone volume	1.5	2.5	4.2	-2.0	-0.7	1.5	1.4	1.8	-1.7
Bone: connectivity density	0.9	1.4	2.5	-1.2	-0.8	0.9	1.3	1.2	-1.6
Bone: cortical apparent density	0.6	0.7	2.3	1.5	-1.4	-0.3	-0.2	-0.2	0.1
Bone: cortical area	3.7	5.6	7.5	-2.1	-2.0	2.2	2.6	2.7	-2.6
Bone: cortical porosity	1.0	1.0	2.3	0.4	0.9	-1.5	-0.7	-1.2	1.0
Bone: cortical porosity	2.2	2.4	3.3	0.7	1.5	-1.8	-1.5	-1.8	1.6
Bone: cortical thickness	2.1	3.4	5.1	-1.5	-1.6	1.4	2.2	2.0	-2.2
Bone: cortical thickness	0.9	1.1	2.0	-1.4	-0.1	0.1	1.3	1.0	-1.4
Bone: cortical tissue density	0.6	0.8	2.9	1.7	-1.2	-0.5	-0.4	-0.4	0.3
Bone: elastic displacement	0.5	0.5	1.2	-0.7	-0.2	-0.5	1.1	0.2	-1.1
Bone: elastic work	0.8	1.1	2.3	-1.2	-0.5	0.4	1.1	1.0	-1.5
Bone: endosteal estimation	1.1	2.3	4.5	-1.3	-1.4	2.1	1.0	1.7	-1.3
Bone: endosteal perimeter	1.4	2.9	5.0	-2.2	-0.5	2.0	1.6	1.9	-1.4
Bone: final force	2.6	4.3	6.6	-1.5	-2.1	1.8	1.9	2.6	-2.4
Bone: final moment	3.2	5.2	7.7	-1.9	-2.0	2.1	2.2	2.8	-2.6
Bone: marrow area	1.1	2.3	4.5	-1.3	-1.4	2.1	1.0	1.7	-1.3
Bone: maximum diameter	3.0	5.5	7.2	-2.2	-1.7	2.6	2.4	2.7	-2.2
Bone: maximum force	3.4	5.9	9.2	-2.2	-2.0	2.4	2.2	3.0	-2.7
Bone: maximum moment	4.2	7.2	10.6	-2.6	-1.9	2.7	2.6	3.3	-2.9
Bone: minimum diameter	1.0	1.9	3.5	-0.6	-1.9	1.3	1.3	1.4	-1.4
Bone: periosteal estimation	2.8	5.7	7.8	-2.1	-2.1	2.7	2.1	2.8	-2.4
Bone: periosteal perimeter	3.8	6.3	8.0	-2.6	-1.7	2.5	2.7	2.8	-2.6
Bone: post-yield work	0.2	0.3	0.9	-0.3	-0.2	1.0	0.1	0.8	0.1
Bone: stiffness	3.3	5.2	8.3	-1.9	-2.0	2.6	1.9	2.9	-2.3
Bone: tissue strength	1.1	1.1	2.4	-1.1	-0.2	1.5	0.9	1.2	-0.8
Bone: trabecular number	0.9	1.4	3.1	-1.8	0.1	1.0	1.0	1.2	-1.2
Bone: trabecular spacing	1.8	2.3	3.8	1.7	0.7	-1.5	-1.3	-1.9	1.6
Bone: trabecular thickness	1.1	1.3	2.0	-0.5	-1.4	1.1	1.0	1.4	-1.1
Bone: trabecular tissue density	0.1	0.2	0.5	0.5	-0.7	0.6	0.2	0.3	0.0
Breakpoint value in progressive ratio session	0.4	0.5	1.4	0.6	-1.2	-0.5	0.5	0.5	-0.6
Distance traveled before self-admin	4.2	4.5	9.2	-0.3	-3.0	2.2	1.9	2.2	-2.1
Distance traveled after self-admin	4.0	4.4	6.5	-1.2	-2.4	2.1	2.0	2.6	-2.2
Delta time in closed arm before/after self-admin	0.3	0.3	1.1	0.4	0.2	-0.5	-1.0	-0.7	0.2
Delta time in open arm before/after self-admin	0.2	0.2	0.6	0.7	-0.2	-0.2	-0.0	-0.3	0.7
Diff in mean of infusions in LGA sessions	0.2	0.2	1.1	0.1	-0.0	-1.1	0.2	-0.1	0.0
Extinction: sum of active levers before priming	0.6	0.6	1.5	-0.1	-0.9	1.2	0.6	0.6	-0.8
Active lever presses in extinction session 6	0.7	0.7	1.5	1.2	-0.2	-1.2	-0.4	-0.7	0.4
Delta distance traveled before/after self-admin	0.1	0.1	0.2	-0.5	0.1	-0.1	0.2	0.3	0.0
Delta ambulatory time before/after self-admin	0.1	0.1	0.3	-0.3	0.4	-0.6	0.1	0.1	0.1
Time in closed arm before self-admin	2.9	3.3	6.8	-0.1	-2.6	2.2	1.7	1.9	-1.3
Time in closed arm after self-admin	0.3	0.3	1.3	0.5	-1.1	0.4	-0.2	0.2	-0.2
Time in open arm before self-admin	0.6	0.6	2.1	-0.2	1.1	-1.4	-0.4	-0.5	0.0
Time in open arm after self-admin	1.9	2.1	3.0	1.2	1.3	-1.7	-1.3	-1.6	1.6
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.3	0.2	-0.5	0.5	-0.0	0.3	-0.2
Time to tail flick, vehicle, before self-admin	0.9	0.9	2.8	0.3	1.7	0.1	-0.8	-1.0	1.0
Time to tail flick, vehicle, after self-admin	1.1	1.1	1.8	1.3	0.3	-0.8	-1.0	-1.3	1.2
Time to tail flick, test, before self-admin	0.6	0.6	1.7	-0.6	-0.1	0.6	1.3	0.3	-0.9
Time to tail flick, test, after self-admin	0.3	0.3	1.0	0.4	-0.5	1.0	-0.4	-0.1	0.2
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.9	0.7	-0.9	-0.3	-0.1	-0.1	-0.1
Delta time to tail flick, test, before/after SA	0.5	0.5	1.6	0.2	0.2	0.4	-1.3	-0.3	0.9
Ambulatory time before self-admin	3.4	3.6	7.2	-0.6	-2.7	1.9	1.5	2.1	-1.9
Ambulatory time after self-admin	3.6	3.9	6.0	-1.2	-2.3	1.9	1.8	2.5	-2.0
Total heroin consumption	0.5	0.6	1.3	0.4	-1.1	0.4	0.9	0.8	-0.7
Area under the delay curve	0.2	0.2	0.4	-0.6	0.6	0.4	-0.5	0.4	0.1
Delay disc. indifference point, 0s delay	1.1	1.2	3.2	-1.8	0.7	1.1	0.6	1.0	-0.9
Delay disc. indifference point, 16s delay	0.1	0.1	0.2	-0.3	-0.1	0.4	-0.1	0.3	-0.3
Delay disc. indifference point, 2s delay	0.2	0.3	0.6	-0.2	0.5	0.8	-0.7	0.3	0.3
Delay disc. indifference point, 24s delay	0.4	0.4	0.6	0.6	0.3	-0.6	-0.8	-0.6	0.8
Delay disc. indifference point, 4s delay	0.2	0.2	0.5	-0.5	0.6	0.4	-0.7	0.1	0.4
Delay disc. indifference point, 8s delay	0.3	0.3	0.6	-0.8	0.5	0.4	-0.2	0.8	-0.1
Delay discount exponential model param	0.2	0.2	0.5	0.4	-0.6	-0.3	0.7	-0.2	-0.3
Delay discount hyperbolic model param	0.2	0.2	0.5	0.4	-0.6	-0.4	0.7	-0.3	-0.3
Fecal boli incidents, locomotor time 1	3.9	4.2	7.1	-0.0	-2.5	1.6	2.7	1.5	-2.7
Change in fecal boli incidents, locomotor task	5.9	5.6	9.0	0.7	2.8	-2.1	-3.0	-2.2	2.7
Time >=10cm from walls, locomotor time 1	0.6	0.6	2.1	0.8	-1.5	0.6	0.1	0.4	-0.3
Bouts of movement, locomotor time 1	0.6	0.6	1.0	0.9	0.6	-1.0	-0.8	-0.8	0.6
Total resting periods, locomotor time 1	0.6	0.7	1.0	1.0	0.5	-0.9	-0.9	-0.9	0.6
Rest time, locomotor task time 1	3.5	3.8	8.5	2.9	0.1	-1.5	-2.0	-2.2	1.8
Distance moved, locomotor task time 1	1.9	2.0	4.5	-2.1	0.2	1.5	1.5	1.5	-1.0
Vertical activity count, locomotor time 1	4.2	4.4	10.0	-3.2	0.1	1.9	2.1	2.3	-1.7
Time >=10cm from walls, locomotor time 2	0.4	0.4	1.5	1.2	-0.9	0.1	-0.3	-0.4	-0.3
Bouts of movement, locomotor time 2	2.0	2.1	3.0	1.6	1.0	-1.3	-1.7	-1.5	1.5
Total resting periods, locomotor time 2	3.1	3.4	4.9	2.0	1.2	-1.7	-2.2	-1.8	2.0
Rest time, locomotor task time 2	3.4	4.0	8.5	2.9	0.0	-2.1	-1.8	-1.9	2.0
Distance moved, locomotor task time 2	1.8	2.1	3.1	-1.7	-0.5	1.8	1.4	1.5	-1.3
Vertical activity count, locomotor time 2	3.8	4.2	7.5	-2.7	-0.3	2.3	1.9	2.2	-2.0
Weight adjusted by age	1.1	1.3	2.7	1.6	-0.4	-0.3	-1.7	-0.9	1.1
Seeking ratio, delayed vs. immediate footshock	1.9	2.2	3.7	-1.9	-0.2	1.8	0.8	1.9	-1.5
Locomotion in novel chamber	2.9	3.6	5.2	-1.7	-0.9	2.0	2.3	1.9	-2.2
Locomotion in novel chamber post-restriction	0.5	0.6	1.2	-0.8	-0.5	0.8	1.1	0.8	-0.6
Progressive ratio	0.1	0.1	0.2	0.5	-0.3	-0.1	0.1	-0.3	-0.1
Food seeking constrained by brief footshock	0.7	0.9	2.9	1.7	-1.1	-0.4	-0.7	-0.5	0.6
Seeking ratio, punishment vs. effort	0.0	0.1	0.1	0.2	-0.2	-0.0	-0.3	0.0	0.4
Run reversals in cocaine runway, females	0.5	0.5	1.2	-0.2	-0.8	0.4	0.9	0.4	-1.1
Run reversals in cocaine runway, males	0.6	0.5	1.5	1.1	-1.2	0.3	0.2	0.3	-0.5
Latency to leave start box in cocaine runway	0.7	0.7	1.2	0.4	0.9	-1.0	-1.0	-0.4	1.1
Latency to leave start box in cocaine runway, F	0.1	0.2	0.4	-0.2	0.4	0.3	-0.2	0.6	0.4
Latency to leave start box in cocaine runway, M	4.1	3.9	7.6	1.2	1.6	-2.8	-1.9	-2.1	1.9
Cd content in liver	2.1	2.3	3.3	-1.1	-1.1	1.5	1.7	1.8	-1.7
Co content in liver	0.7	0.8	1.4	-1.2	-0.3	0.0	1.1	0.9	-1.1
Cu content in liver	0.6	0.7	1.2	1.1	0.2	-1.1	-0.8	-0.4	0.9
Fe content in liver	0.4	0.5	1.4	-1.2	0.5	0.6	0.6	0.6	-0.5
K content in liver	0.2	0.2	0.5	0.3	0.6	-0.0	-0.5	-0.2	0.7
Mg content in liver	0.0	0.0	0.2	0.4	-0.0	0.1	-0.2	0.1	0.2
Mn content in liver	0.6	0.7	1.8	-0.7	-0.4	1.3	0.5	0.9	-0.7
Na content in liver	1.9	2.0	3.3	-1.8	-0.6	1.5	1.2	1.7	-1.4
Rb content in liver	0.4	0.5	1.8	1.3	-1.0	-0.2	0.1	-0.3	0.1
Se content in liver	2.6	3.1	4.9	1.9	1.2	-1.2	-2.1	-1.7	2.2
Sr content in liver	3.3	3.0	7.9	-2.8	0.3	1.4	1.5	1.7	-1.6
Zn content in liver	1.5	1.6	3.3	-0.0	-1.8	0.9	1.4	1.5	-1.3