| # | tissue | modality | RNA phenotype | h2 | h2 se | h2 P | eQTL R2 | BLUP R2 | ENET R2 | LASSO R2 | eQTL P | BLUP P | ENET P | LASSO P |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | gene expression | ENSRNOG00000069670 | 0.120 | 0.06300 | 1.7e-13 | 0.099 | 0.102 | 0.099 | 0.104 | 4.8e-11 | 2.2e-11 | 4.6e-11 | 1.3e-11 |
| 2 | Liver | gene expression | ENSRNOG00000069670 | 0.830 | 0.05400 | 0.0e+00 | 0.579 | 0.493 | 0.637 | 0.640 | 8.0e-79 | 2.3e-62 | 4.8e-92 | 9.4e-93 |
| 3 | Liver | intron excision ratio | chr14:20634955:20635986 | 0.863 | 0.01330 | 0.0e+00 | 0.263 | 0.261 | 0.380 | 0.378 | 3.8e-29 | 7.3e-29 | 1.6e-44 | 3.4e-44 |
| 4 | Liver | intron excision ratio | chr14:20649731:20650782 | 0.870 | 0.01113 | 0.0e+00 | 0.199 | 0.195 | 0.369 | 0.368 | 1.1e-21 | 3.2e-21 | 6.8e-43 | 9.6e-43 |
| 5 | Liver | intron excision ratio | chr14:20719904:20721433 | 0.883 | 0.00755 | 0.0e+00 | 0.367 | 0.346 | 0.507 | 0.513 | 1.2e-42 | 8.8e-40 | 8.8e-65 | 5.6e-66 |
| 6 | Liver | intron excision ratio | chr14:20733118:20737007 | 0.885 | 0.00781 | 0.0e+00 | 0.342 | 0.276 | 0.472 | 0.494 | 3.7e-39 | 1.2e-30 | 7.7e-59 | 1.8e-62 |
| 7 | Liver | mRNA stability | ENSRNOG00000069670 | 0.894 | 0.00390 | 0.0e+00 | 0.281 | 0.129 | 0.453 | 0.451 | 3.1e-31 | 3.7e-14 | 1.4e-55 | 2.7e-55 |
All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, the gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method.
| Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|
Trait | Avg chi2 ratio | Avg chi2 | Max chi2 | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|---|---|---|
| Extensor digitorum longus weight | 6.9 | 27.8 | 48.9 | 7.0 | 6.6 | 3.6 | 3.7 | -4.7 | -4.4 | 5.9 |
| Latency to leave start box in cocaine runway, F | 4.4 | 4.8 | 5.8 | -2.4 | -2.1 | -2.3 | -2.2 | 2.1 | 2.0 | -2.3 |
| Latency to leave start box in cocaine runway | 4.2 | 4.5 | 6.4 | -2.0 | -1.6 | -2.5 | -2.4 | 2.1 | 2.1 | -2.0 |
| Bone: minimum diameter | 3.5 | 6.5 | 12.8 | -3.6 | -3.4 | -1.6 | -1.3 | 2.1 | 1.9 | -3.0 |
| Mean time between licks in bursts | 3.3 | 4.6 | 7.2 | 2.6 | 2.7 | 1.5 | 1.7 | -2.1 | -1.9 | 2.2 |
| Tibialis anterior weight | 2.6 | 8.8 | 16.3 | 4.0 | 4.0 | 1.7 | 1.9 | -2.6 | -2.4 | 3.1 |
| Ambulatory time after self-admin | 2.3 | 2.5 | 3.9 | -1.9 | -2.0 | -1.0 | -1.2 | 1.6 | 1.6 | -1.6 |
| Condit. Reinf. active-inactive response ratio | 2.2 | 2.3 | 3.4 | 1.7 | 1.9 | 1.1 | 1.4 | -1.5 | -1.4 | 1.7 |
| Sum of active levers in priming session hrs 5-6 | 2.2 | 2.1 | 3.8 | -0.9 | -1.0 | -1.6 | -1.9 | 1.6 | 1.6 | -1.3 |
| Delay discounting time to switch 0 sec | 2.1 | 3.3 | 6.2 | 2.5 | 2.3 | 1.2 | 1.3 | -1.6 | -1.4 | 1.9 |
| Progressive ratio test 1 inactive lever presses | 2.1 | 2.2 | 2.8 | -1.7 | -1.7 | -1.2 | -1.5 | 1.5 | 1.3 | -1.6 |
| Condit. Reinf. inactive responses | 2.1 | 2.5 | 3.3 | -1.8 | -1.6 | -1.3 | -1.5 | 1.6 | 1.6 | -1.6 |
| Bone: cortical porosity | 2.1 | 2.3 | 3.7 | 1.9 | 1.7 | 1.2 | 1.3 | -1.4 | -1.3 | 1.6 |
| Distance traveled after self-admin | 2.0 | 2.2 | 4.0 | -1.8 | -2.0 | -0.8 | -0.9 | 1.5 | 1.4 | -1.6 |
| Std. dev. time between licks in bursts | 1.8 | 2.2 | 3.0 | 1.3 | 0.9 | 1.6 | 1.7 | -1.6 | -1.5 | 1.5 |
| Conditioned reinforcement - inactives | 1.7 | 1.9 | 2.4 | -1.3 | -1.2 | -1.5 | -1.4 | 1.6 | 1.4 | -1.3 |
| Weight adjusted by age | 1.7 | 1.8 | 2.4 | 1.2 | 0.9 | 1.5 | 1.5 | -1.5 | -1.4 | 1.4 |
| Intermittent access intake day 1-15 change | 1.6 | 1.6 | 2.6 | 1.1 | 1.0 | 1.4 | 1.6 | -1.1 | -1.2 | 1.2 |
| Time in open arm before self-admin | 1.6 | 1.7 | 2.5 | 1.3 | 0.8 | 1.6 | 1.5 | -1.2 | -1.2 | 1.4 |
| Distance moved, locomotor task time 2 | 1.6 | 1.8 | 3.3 | 1.3 | 1.2 | 1.0 | 1.3 | -1.4 | -1.8 | 1.1 |
| Seeking ratio, delayed vs. immediate footshock | 1.6 | 1.8 | 2.3 | -1.3 | -1.2 | -1.4 | -1.5 | 1.4 | 1.3 | -1.1 |
| Food consumed during 24 hour testing period | 1.5 | 1.8 | 3.7 | -1.7 | -1.9 | -0.6 | -0.8 | 1.4 | 1.2 | -1.4 |
| Liver weight, right | 1.4 | 2.4 | 4.1 | -2.0 | -2.0 | -0.8 | -1.3 | 1.3 | 1.3 | -1.7 |
| Indifference point AUC | 1.4 | 1.7 | 3.4 | -1.8 | -1.3 | -1.1 | -1.3 | 1.1 | 0.8 | -1.4 |
| Compulsive drug intake | 1.4 | 1.4 | 3.2 | -0.5 | -0.3 | -1.6 | -1.8 | 1.2 | 1.4 | -0.5 |
| Delay discounting water rate 18 sec | 1.3 | 1.7 | 3.6 | -1.5 | -1.9 | -0.7 | -0.6 | 1.3 | 1.2 | -1.5 |
| Social response proportion | 1.3 | 1.4 | 2.0 | -1.4 | -0.9 | -1.2 | -1.3 | 1.2 | 1.2 | -1.0 |
| Delay disc. indifference point, 8s delay | 1.3 | 1.3 | 2.2 | 1.2 | 1.4 | 0.6 | 0.7 | -1.2 | -1.5 | 1.1 |
| Run reversals in cocaine runway, females | 1.3 | 1.3 | 3.3 | -1.5 | -1.8 | -0.2 | -0.2 | 0.9 | 0.8 | -1.4 |
| Parametrial fat weight | 1.2 | 2.4 | 2.9 | -1.7 | -1.7 | -1.4 | -1.4 | 1.5 | 1.5 | -1.6 |
| Progressive ratio test 2 inactive lever presses | 1.2 | 1.4 | 1.7 | -1.3 | -1.1 | -1.2 | -1.1 | 1.3 | 1.1 | -1.2 |
| Locomotion velocity, session 7 | 1.2 | 1.3 | 2.9 | -1.7 | -1.4 | -0.8 | -0.9 | 0.9 | 0.7 | -1.3 |
| Bone: cortical porosity | 1.2 | 1.3 | 2.5 | 1.6 | 1.2 | 1.0 | 0.9 | -0.9 | -0.7 | 1.3 |
| Delta time in open arm before/after self-admin | 1.2 | 1.1 | 1.6 | -1.3 | -1.2 | -0.9 | -1.1 | 1.0 | 1.0 | -1.1 |
| Extinction: sum of active levers before priming | 1.2 | 1.2 | 1.7 | -0.8 | -0.8 | -1.3 | -1.3 | 1.2 | 1.1 | -1.0 |
| Rb content in liver | 1.2 | 1.6 | 2.5 | 1.1 | 1.2 | 1.1 | 1.0 | -1.4 | -1.6 | 1.1 |
| Mean num. licks in bursts | 1.1 | 1.3 | 1.7 | -1.1 | -0.7 | -1.2 | -1.1 | 1.2 | 1.2 | -1.3 |
| Water consumed over 24 hours | 1.1 | 1.3 | 2.3 | -1.5 | -1.5 | -0.8 | -0.8 | 1.2 | 1.0 | -1.2 |
| Intermitt. access day 15 inactive lever presses | 1.1 | 1.2 | 2.0 | -1.3 | -1.4 | -0.8 | -0.9 | 1.1 | 0.9 | -1.2 |
| Short access day 10 total inactive lever presses | 1.1 | 1.2 | 1.8 | -1.2 | -1.4 | -0.8 | -0.9 | 1.2 | 1.1 | -1.0 |
| Total locomotion distance, hab. session 1 | 1.1 | 1.6 | 3.8 | -1.6 | -2.0 | -0.6 | -0.6 | 1.1 | 1.0 | -1.3 |
| Short access day 1 total inactive lever presses | 1.0 | 1.1 | 2.1 | -1.2 | -1.4 | -0.7 | -0.7 | 1.1 | 0.8 | -1.1 |
| Delay disc. indifference point, 2s delay | 1.0 | 1.2 | 2.8 | -1.7 | -1.7 | -0.4 | -0.4 | 0.6 | 0.4 | -1.3 |
| Locomotion in novel chamber post-restriction | 1.0 | 1.1 | 1.8 | -1.1 | -0.7 | -1.2 | -1.3 | 0.8 | 0.8 | -1.3 |
| BMI with tail | 0.9 | 2.8 | 6.1 | 2.3 | 2.5 | 0.8 | 0.7 | -1.6 | -1.4 | 1.6 |
| Intermittent access intake escalation | 0.9 | 0.9 | 1.7 | 0.7 | 0.5 | 1.2 | 1.3 | -0.8 | -0.8 | 0.9 |
| Stereotopy head waving bouts, day 3 | 0.9 | 1.0 | 1.9 | 1.0 | 1.0 | 0.7 | 0.8 | -1.1 | -1.4 | 1.0 |
| Locomotion velocity, hab. session 1 | 0.9 | 1.3 | 3.5 | -1.4 | -1.9 | -0.4 | -0.4 | 1.0 | 0.9 | -1.1 |
| Time in novel zone, hab. session 2 | 0.9 | 1.0 | 2.6 | 0.1 | 0.6 | 0.8 | 1.1 | -1.3 | -1.6 | 0.4 |
| Bone: endosteal estimation | 0.9 | 2.0 | 4.9 | -2.0 | -2.2 | -0.4 | -0.4 | 1.0 | 0.8 | -1.7 |
| Delta time in closed arm before/after self-admin | 0.9 | 0.9 | 2.1 | 1.2 | 1.5 | 0.4 | 0.6 | -0.9 | -0.8 | 1.0 |
| Time to tail flick, test, after self-admin | 0.9 | 0.9 | 2.7 | -1.6 | -1.6 | 0.2 | 0.5 | 0.2 | 0.0 | -0.9 |
| Delay discounting total patch changes 6 sec | 0.8 | 1.3 | 1.8 | -1.3 | -1.2 | -1.0 | -1.1 | 1.1 | 0.8 | -1.3 |
| Reaction time omissions | 0.8 | 1.0 | 2.5 | 1.4 | 1.6 | 0.4 | 0.7 | -0.7 | -0.7 | 1.1 |
| Intermitt. access day 1 inactive lever presses | 0.8 | 0.9 | 1.4 | -1.2 | -1.1 | -0.7 | -0.9 | 0.9 | 0.8 | -0.9 |
| Total sessions with >9 infusions | 0.8 | 0.9 | 2.5 | 1.6 | 1.1 | 0.8 | 0.5 | -0.6 | -0.5 | 1.1 |
| Bone: marrow area | 0.8 | 1.8 | 4.6 | -1.9 | -2.2 | -0.3 | -0.3 | 0.9 | 0.8 | -1.6 |
| Total heroin consumption | 0.8 | 1.0 | 2.1 | -1.3 | -1.4 | -0.4 | -0.5 | 0.8 | 0.7 | -1.2 |
| Rest time, locomotor task time 1 | 0.8 | 0.8 | 1.3 | -1.0 | -1.1 | -0.7 | -0.7 | 1.0 | 1.1 | -0.8 |
| Cd content in liver | 0.8 | 0.8 | 1.9 | 1.3 | 1.4 | 0.3 | 0.4 | -0.6 | -0.5 | 1.1 |
| Delay discounting water rate 0 sec | 0.7 | 1.0 | 2.3 | -1.5 | -1.5 | -0.3 | -0.4 | 0.7 | 0.5 | -1.4 |
| Delay discounting water rate 24 sec | 0.7 | 1.0 | 2.2 | -1.0 | -1.5 | -0.5 | -0.4 | 1.1 | 0.9 | -1.2 |
| Cocaine response after cond. corrected | 0.7 | 0.8 | 1.0 | -0.9 | -0.9 | -0.7 | -0.9 | 1.0 | 1.0 | -0.9 |
| Cocaine response after cond. not corrected | 0.7 | 0.8 | 1.0 | -0.9 | -1.0 | -0.6 | -0.8 | 0.9 | 0.9 | -0.9 |
| Pavlov. Cond. intertrial magazine entries | 0.7 | 0.9 | 2.4 | -1.6 | -1.3 | -0.5 | -0.6 | 0.4 | 0.4 | -1.0 |
| Locomotion velocity, session 1 | 0.7 | 0.7 | 1.3 | 0.8 | 1.2 | 0.4 | 0.3 | -1.0 | -1.0 | 0.9 |
| Delta time to tail flick, test, before/after SA | 0.7 | 0.6 | 1.4 | -1.2 | -0.8 | -0.6 | -0.4 | 0.6 | 0.6 | -0.9 |
| Zn content in liver | 0.7 | 0.7 | 1.4 | -1.0 | -1.2 | -0.3 | -0.7 | 0.8 | 1.0 | -0.7 |
| Liver weight, left | 0.6 | 1.0 | 2.3 | -1.5 | -1.5 | -0.2 | -0.7 | 0.6 | 0.6 | -1.1 |
| Social time | 0.6 | 0.7 | 1.3 | -1.1 | -0.9 | -0.6 | -0.7 | 0.7 | 0.8 | -1.1 |
| Saline control response | 0.6 | 0.8 | 1.1 | -1.0 | -1.1 | -0.6 | -0.6 | 0.9 | 0.9 | -1.0 |
| Locomotion velocity, session 3 | 0.6 | 0.7 | 0.9 | -1.0 | -0.9 | -0.6 | -0.7 | 0.8 | 0.9 | -1.0 |
| Locomotion distance, session 7 | 0.6 | 0.8 | 1.6 | -1.3 | -1.3 | -0.3 | -0.5 | 0.6 | 0.8 | -1.0 |
| Locomotion velocity, hab. session 2 | 0.6 | 0.8 | 1.4 | -1.0 | -1.2 | -0.6 | -0.5 | 1.0 | 0.9 | -0.7 |
| Time in open arm after self-admin | 0.6 | 0.6 | 1.1 | -1.0 | -1.0 | -0.5 | -0.8 | 0.7 | 0.7 | -0.7 |
| Time >=10cm from walls, locomotor time 1 | 0.6 | 0.6 | 1.8 | 1.2 | 1.3 | 0.2 | 0.0 | -0.4 | -0.2 | 1.0 |
| Rest time, locomotor task time 2 | 0.6 | 0.7 | 1.4 | -1.0 | -1.2 | -0.4 | -0.5 | 1.0 | 1.2 | -0.4 |
| Run reversals in cocaine runway, males | 0.6 | 0.6 | 0.9 | 0.5 | 0.4 | 0.9 | 0.9 | -0.8 | -0.9 | 0.8 |
| K content in liver | 0.6 | 0.6 | 1.4 | -1.2 | -0.9 | -0.6 | -0.8 | 0.5 | 0.6 | -0.9 |
| Glucose | 0.5 | 0.7 | 1.8 | -1.3 | -1.3 | -0.2 | -0.3 | 0.6 | 0.5 | -1.0 |
| Length with tail | 0.5 | 1.7 | 2.9 | -1.7 | -1.6 | -0.9 | -0.6 | 1.3 | 1.0 | -1.6 |
| Delay discounting total patch changes 24 sec | 0.5 | 0.6 | 1.2 | -1.1 | -0.9 | -0.6 | -0.6 | 0.7 | 0.5 | -0.8 |
| Delay discounting water rate 6 sec | 0.5 | 0.7 | 1.3 | -1.1 | -0.9 | -0.7 | -0.5 | 0.7 | 0.6 | -1.0 |
| Condit. Reinf. lever presses | 0.5 | 0.7 | 1.0 | -0.8 | -1.0 | -0.5 | -0.6 | 1.0 | 1.0 | -0.8 |
| Pavlov. Cond. magazine entry number | 0.5 | 0.7 | 1.9 | -1.4 | -0.9 | -0.5 | -0.7 | 0.5 | 0.4 | -0.9 |
| Intermitt. access escalation Index | 0.5 | 0.4 | 1.0 | 0.9 | 0.9 | 0.2 | 0.4 | -0.4 | -0.3 | 1.0 |
| Stereotopy head waving duration, day 3 | 0.5 | 0.7 | 1.7 | 0.4 | 0.2 | 0.7 | 0.9 | -0.9 | -1.3 | 0.7 |
| Degree of sensitization distance | 0.5 | 0.5 | 1.2 | -1.1 | -1.1 | -0.0 | 0.0 | 0.3 | 0.1 | -0.9 |
| Total locomotion distance, hab. session 2 | 0.5 | 0.7 | 1.2 | -1.0 | -1.1 | -0.6 | -0.4 | 0.9 | 0.8 | -0.7 |
| Bone: tissue strength | 0.5 | 0.5 | 0.9 | -0.9 | -0.8 | -0.5 | -0.5 | 0.7 | 0.6 | -0.9 |
| Delay disc. indifference point, 16s delay | 0.5 | 0.5 | 1.3 | 0.7 | 1.1 | -0.0 | 0.3 | -0.7 | -1.1 | 0.6 |
| Seeking ratio, punishment vs. effort | 0.5 | 0.6 | 0.9 | -0.7 | -0.6 | -0.7 | -0.9 | 0.7 | 0.9 | -0.9 |
| Fe content in liver | 0.5 | 0.6 | 0.9 | 0.8 | 1.0 | 0.4 | 0.4 | -1.0 | -0.8 | 0.6 |
| Mn content in liver | 0.5 | 0.6 | 1.3 | 0.2 | 0.3 | 0.7 | 1.0 | -1.0 | -1.2 | 0.4 |
| Heart weight | 0.4 | 0.6 | 1.5 | 0.8 | 0.6 | 0.6 | 1.2 | -0.6 | -0.8 | 0.7 |
| Indifference point function ln k | 0.4 | 0.6 | 1.1 | 1.1 | 0.8 | 0.7 | 0.8 | -0.7 | -0.5 | 0.8 |
| Indifference point function log k | 0.4 | 0.6 | 1.1 | 1.1 | 0.8 | 0.7 | 0.8 | -0.7 | -0.5 | 0.8 |
| Locomotion distance, session 8 | 0.4 | 0.6 | 2.1 | -1.0 | -1.5 | -0.0 | 0.0 | 0.6 | 0.5 | -0.9 |
| Condit. Reinf. active minus inactive responses | 0.4 | 0.4 | 1.1 | 0.7 | 1.0 | 0.3 | 0.3 | -0.6 | -0.4 | 0.6 |
| Time in novel zone, hab. session 1 | 0.4 | 0.4 | 1.7 | 0.7 | 1.3 | 0.1 | 0.0 | -0.5 | -0.5 | 0.5 |
| Time in familiar zone, hab. session 2 | 0.4 | 0.4 | 1.1 | 0.2 | 0.1 | -0.6 | -0.8 | 0.7 | 1.1 | -0.1 |
| Bone: connectivity density | 0.4 | 0.6 | 1.0 | 1.0 | 0.8 | 0.7 | 0.5 | -0.9 | -0.7 | 0.7 |
| Bone: periosteal estimation | 0.4 | 0.8 | 1.9 | -1.4 | -1.4 | -0.3 | -0.1 | 0.5 | 0.3 | -1.2 |
| Bone: stiffness | 0.4 | 0.6 | 1.7 | -1.3 | -0.9 | -0.3 | -0.2 | 0.2 | 0.0 | -1.2 |
| Time in closed arm before self-admin | 0.4 | 0.4 | 1.3 | -1.1 | -1.1 | -0.0 | 0.1 | 0.3 | 0.1 | -0.7 |
| Time to tail flick, vehicle, after self-admin | 0.4 | 0.4 | 1.2 | -0.7 | -1.1 | 0.1 | 0.3 | 0.6 | 0.6 | -0.7 |
| Delay disc. indifference point, 24s delay | 0.4 | 0.4 | 0.8 | 0.3 | 0.3 | 0.6 | 0.8 | -0.7 | -0.9 | 0.4 |
| Fecal boli incidents, locomotor time 1 | 0.4 | 0.4 | 1.3 | 1.1 | 1.0 | -0.0 | 0.2 | -0.1 | -0.1 | 0.8 |
| Bouts of movement, locomotor time 1 | 0.4 | 0.5 | 0.9 | 0.8 | 1.0 | 0.3 | 0.6 | -0.6 | -0.5 | 0.9 |
| Vertical activity count, locomotor time 1 | 0.4 | 0.4 | 1.4 | -0.3 | 0.1 | 0.3 | 0.4 | -0.9 | -1.2 | -0.2 |
| Progressive ratio | 0.4 | 0.4 | 0.6 | 0.8 | 0.7 | 0.5 | 0.6 | -0.5 | -0.7 | 0.8 |
| Mg content in liver | 0.4 | 0.4 | 1.3 | -1.1 | -0.7 | -0.4 | -0.5 | 0.2 | 0.2 | -0.8 |
| Na content in liver | 0.4 | 0.4 | 0.9 | -1.0 | -0.6 | -0.5 | -0.8 | 0.4 | 0.4 | -0.7 |
| Length without tail | 0.3 | 0.7 | 1.0 | -0.9 | -1.0 | -0.7 | -0.6 | 0.9 | 0.9 | -1.0 |
| Intraocular pressure | 0.3 | 0.5 | 1.2 | 0.9 | 1.1 | 0.5 | 0.5 | -0.7 | -0.5 | 0.4 |
| Number of licking bursts | 0.3 | 0.3 | 0.5 | 0.5 | 0.4 | 0.6 | 0.5 | -0.6 | -0.7 | 0.7 |
| Delay discounting total patch changes 0 sec | 0.3 | 0.4 | 0.7 | -0.6 | -0.8 | -0.4 | -0.7 | 0.7 | 0.6 | -0.7 |
| Delay discounting water rate 12 sec | 0.3 | 0.5 | 0.8 | -0.7 | -0.9 | -0.4 | -0.1 | 0.8 | 0.8 | -0.8 |
| Light reinforcement 1 | 0.3 | 0.5 | 1.1 | -1.1 | -0.8 | -0.7 | -0.6 | 0.6 | 0.3 | -0.9 |
| Conditioned locomotion | 0.3 | 0.4 | 1.0 | 1.0 | 0.8 | 0.5 | 0.4 | -0.4 | -0.4 | 0.6 |
| Pavlov. Cond. magazine entry latency | 0.3 | 0.3 | 0.9 | 0.9 | 0.7 | 0.2 | 0.4 | -0.2 | -0.2 | 0.7 |
| Pavlov. Cond. latency score | 0.3 | 0.4 | 0.9 | 0.9 | 0.6 | 0.4 | 0.6 | -0.3 | -0.3 | 0.8 |
| Conditioned reinforcement - actives | 0.3 | 0.3 | 0.6 | 0.5 | 0.4 | 0.7 | 0.8 | -0.5 | -0.5 | 0.4 |
| Baseline Anxiety | 0.3 | 0.3 | 0.6 | -0.3 | -0.4 | -0.7 | -0.6 | 0.7 | 0.8 | -0.4 |
| Short access day 10 total infusions | 0.3 | 0.3 | 0.9 | 0.1 | 0.1 | -0.6 | -1.0 | 0.6 | 0.7 | -0.1 |
| One hour access (0.3 mA shock) | 0.3 | 0.3 | 0.5 | -0.5 | -0.5 | -0.6 | -0.7 | 0.7 | 0.7 | -0.4 |
| Pavlov. Cond. lever contacts | 0.3 | 0.3 | 1.1 | -1.1 | -0.8 | -0.4 | -0.1 | 0.3 | 0.1 | -0.7 |
| Pavlov. Cond. intertrial magazine entries | 0.3 | 0.3 | 1.0 | -0.6 | -0.2 | 0.4 | 0.5 | -0.6 | -1.0 | -0.0 |
| Bone: apparent density | 0.3 | 0.5 | 0.6 | 0.8 | 0.6 | 0.7 | 0.6 | -0.8 | -0.7 | 0.6 |
| Bone: elastic work | 0.3 | 0.3 | 1.1 | 0.5 | 0.0 | -0.3 | -0.4 | 0.8 | 1.1 | 0.2 |
| Distance traveled before self-admin | 0.3 | 0.3 | 0.5 | -0.7 | -0.7 | -0.4 | -0.3 | 0.5 | 0.5 | -0.7 |
| Time to tail flick, vehicle, before self-admin | 0.3 | 0.3 | 1.1 | -1.0 | -0.8 | -0.1 | -0.2 | 0.3 | 0.2 | -0.6 |
| Ambulatory time before self-admin | 0.3 | 0.3 | 0.7 | -0.8 | -0.8 | -0.2 | -0.0 | 0.4 | 0.2 | -0.7 |
| Delay disc. indifference point, 4s delay | 0.3 | 0.3 | 0.7 | -0.5 | -0.2 | -0.8 | -0.9 | 0.6 | 0.4 | -0.4 |
| Total resting periods, locomotor time 1 | 0.3 | 0.3 | 0.7 | 0.7 | 0.9 | 0.2 | 0.3 | -0.5 | -0.3 | 0.7 |
| Distance moved, locomotor task time 1 | 0.3 | 0.4 | 0.9 | 0.4 | 0.3 | 0.5 | 0.7 | -0.7 | -1.0 | 0.4 |
| Vertical activity count, locomotor time 2 | 0.3 | 0.3 | 1.1 | 0.2 | 0.5 | 0.3 | 0.3 | -0.8 | -1.0 | -0.1 |
| Cu content in liver | 0.3 | 0.4 | 1.0 | -1.0 | -0.9 | -0.3 | -0.2 | 0.4 | 0.3 | -0.7 |
| Sr content in liver | 0.3 | 0.2 | 0.6 | 0.4 | 0.4 | 0.3 | 0.8 | -0.4 | -0.6 | 0.4 |
| Left kidney weight | 0.2 | 0.4 | 0.9 | -0.9 | -0.8 | -0.3 | -0.1 | 0.6 | 0.3 | -1.0 |
| Right kidney weight | 0.2 | 0.5 | 1.3 | -1.2 | -0.8 | -0.3 | -0.1 | 0.5 | 0.2 | -1.1 |
| Indifference point 0 sec | 0.2 | 0.4 | 0.7 | -0.6 | -0.8 | -0.3 | -0.6 | 0.6 | 0.6 | -0.6 |
| Delay discounting total patch changes 18 sec | 0.2 | 0.2 | 0.8 | -0.3 | -0.1 | -0.6 | -0.9 | 0.5 | 0.4 | -0.3 |
| Locomotor activity | 0.2 | 0.3 | 1.1 | -0.7 | -1.1 | 0.0 | 0.3 | 0.5 | 0.2 | -0.5 |
| Reaction time mean minus median | 0.2 | 0.3 | 0.8 | 0.9 | 0.8 | -0.2 | -0.1 | -0.2 | -0.2 | 0.5 |
| Reaction time mean minus median AUC | 0.2 | 0.3 | 1.0 | 0.8 | 1.0 | -0.1 | -0.0 | -0.4 | -0.4 | 0.4 |
| Reaction time mean | 0.2 | 0.3 | 0.8 | 0.9 | 0.9 | -0.3 | 0.1 | -0.3 | -0.4 | 0.6 |
| Reaction time mean AUC | 0.2 | 0.3 | 0.6 | 0.8 | 0.7 | -0.2 | 0.1 | -0.3 | -0.5 | 0.4 |
| Median of all reaction times | 0.2 | 0.3 | 0.7 | 0.8 | 0.9 | -0.2 | 0.2 | -0.4 | -0.5 | 0.6 |
| Reaction time premature initiation rate | 0.2 | 0.2 | 0.4 | -0.7 | -0.4 | -0.6 | -0.5 | 0.3 | 0.1 | -0.5 |
| Social responses | 0.2 | 0.2 | 0.6 | -0.8 | -0.5 | -0.3 | -0.3 | 0.4 | 0.2 | -0.6 |
| Condit. Reinf. active-inactive response ratio | 0.2 | 0.2 | 0.3 | -0.4 | -0.4 | -0.4 | -0.6 | 0.5 | 0.4 | -0.4 |
| Pavlov. Cond. index score | 0.2 | 0.2 | 0.6 | 0.8 | 0.4 | 0.4 | 0.5 | -0.2 | -0.2 | 0.6 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.2 | 0.2 | 0.5 | 0.7 | 0.3 | 0.4 | 0.5 | -0.2 | -0.2 | 0.6 |
| Intermittent access intake escalation 2 | 0.2 | 0.2 | 0.5 | -0.1 | -0.2 | 0.6 | 0.7 | -0.3 | -0.5 | -0.0 |
| Short access day 1 total infusions | 0.2 | 0.3 | 0.3 | -0.5 | -0.4 | -0.6 | -0.6 | 0.6 | 0.6 | -0.4 |
| Short access total locomotion | 0.2 | 0.2 | 0.5 | 0.7 | 0.7 | 0.2 | 0.1 | -0.2 | -0.2 | 0.5 |
| Number of responses in last shaping day | 0.2 | 0.2 | 0.6 | 0.8 | 0.6 | 0.1 | -0.1 | -0.3 | -0.2 | 0.5 |
| Context. condit. distance diff. score | 0.2 | 0.3 | 0.6 | -0.4 | -0.8 | -0.2 | -0.1 | 0.5 | 0.7 | -0.6 |
| Locomotion distance, session 3 | 0.2 | 0.2 | 0.5 | -0.1 | -0.0 | -0.4 | -0.5 | 0.5 | 0.7 | -0.3 |
| Stereotopy head waving bouts, day 7 | 0.2 | 0.2 | 0.4 | 0.7 | 0.4 | 0.2 | 0.4 | -0.4 | -0.5 | 0.5 |
| Stereotopy head waving duration, day 7 | 0.2 | 0.3 | 0.5 | 0.7 | 0.7 | 0.0 | 0.2 | -0.4 | -0.6 | 0.6 |
| Total locomotion distance, NPP test | 0.2 | 0.3 | 0.6 | -0.5 | -0.8 | -0.4 | -0.4 | 0.7 | 0.6 | -0.5 |
| Pavlov. Cond. lever latency | 0.2 | 0.3 | 1.0 | 1.0 | 0.7 | 0.3 | 0.1 | -0.2 | 0.1 | 0.6 |
| Bone: cortical apparent density | 0.2 | 0.2 | 1.0 | 0.0 | 0.4 | -0.5 | -1.0 | 0.2 | 0.4 | -0.2 |
| Bone: cortical thickness | 0.2 | 0.3 | 0.7 | 0.7 | 0.9 | 0.2 | 0.5 | -0.4 | -0.4 | 0.5 |
| Bone: cortical thickness | 0.2 | 0.3 | 0.8 | -0.3 | -0.5 | -0.3 | -0.4 | 0.7 | 0.9 | -0.6 |
| Bone: cortical tissue density | 0.2 | 0.2 | 0.9 | 0.2 | 0.5 | -0.4 | -0.9 | 0.1 | 0.4 | -0.0 |
| Bone: endosteal perimeter | 0.2 | 0.4 | 1.2 | -1.0 | -1.1 | -0.3 | -0.1 | 0.5 | 0.3 | -0.7 |
| Bone: maximum diameter | 0.2 | 0.3 | 1.0 | -0.1 | 0.2 | 0.4 | 0.6 | -0.7 | -1.0 | 0.1 |
| Bone: maximum force | 0.2 | 0.3 | 0.6 | -0.7 | -0.8 | -0.1 | 0.0 | 0.4 | 0.3 | -0.8 |
| Bone: maximum moment | 0.2 | 0.4 | 0.9 | -0.8 | -0.8 | -0.2 | -0.1 | 0.5 | 0.5 | -0.9 |
| Bone: periosteal perimeter | 0.2 | 0.3 | 0.8 | -0.8 | -0.9 | -0.3 | -0.1 | 0.5 | 0.3 | -0.7 |
| Bone: trabecular number | 0.2 | 0.3 | 0.5 | 0.6 | 0.5 | 0.5 | 0.2 | -0.7 | -0.6 | 0.5 |
| Bone: trabecular tissue density | 0.2 | 0.3 | 0.7 | 0.5 | 0.8 | 0.1 | 0.3 | -0.6 | -0.6 | 0.5 |
| Active lever presses in extinction session 6 | 0.2 | 0.2 | 0.7 | -0.8 | -0.8 | 0.2 | -0.0 | -0.0 | -0.2 | -0.4 |
| Delta distance traveled before/after self-admin | 0.2 | 0.2 | 0.7 | -0.6 | -0.8 | 0.2 | -0.0 | 0.3 | 0.2 | -0.2 |
| Time to tail flick, test, before self-admin | 0.2 | 0.2 | 0.4 | -0.0 | -0.4 | 0.6 | 0.7 | -0.4 | -0.5 | 0.2 |
| BMI without tail | 0.1 | 0.1 | 0.4 | 0.1 | 0.6 | -0.0 | 0.0 | -0.5 | -0.6 | -0.1 |
| Body weight | 0.1 | 0.3 | 0.9 | 0.7 | 1.0 | -0.0 | 0.2 | -0.4 | -0.5 | 0.1 |
| Epididymis fat weight | 0.1 | 0.2 | 0.6 | 0.3 | 0.4 | 0.4 | 0.6 | -0.6 | -0.8 | 0.1 |
| Tail length | 0.1 | 0.2 | 0.4 | -0.6 | -0.4 | -0.3 | -0.1 | 0.3 | 0.1 | -0.6 |
| Retroperitoneal fat weight | 0.1 | 0.3 | 0.8 | -0.8 | -0.2 | -0.5 | -0.3 | 0.1 | -0.1 | -0.9 |
| Soleus weight | 0.1 | 0.3 | 0.8 | 0.9 | 0.5 | 0.3 | 0.4 | -0.1 | -0.0 | 0.8 |
| Tibia length | 0.1 | 0.2 | 0.5 | -0.7 | -0.5 | -0.4 | -0.3 | 0.3 | 0.0 | -0.7 |
| Times rat made contact with spout | 0.1 | 0.2 | 0.3 | -0.6 | -0.3 | -0.5 | -0.4 | 0.3 | 0.3 | -0.4 |
| Delay discounting total patch changes 12 sec | 0.1 | 0.1 | 0.2 | -0.5 | -0.2 | -0.2 | -0.3 | 0.1 | -0.2 | -0.4 |
| Locomotor testing distance | 0.1 | 0.2 | 0.7 | -0.3 | -0.8 | 0.4 | 0.6 | 0.3 | 0.1 | -0.3 |
| Locomotor testing rearing | 0.1 | 0.1 | 0.5 | 0.1 | -0.4 | 0.5 | 0.7 | -0.1 | -0.3 | -0.1 |
| Reaction time number correct | 0.1 | 0.1 | 0.3 | 0.3 | 0.6 | 0.0 | 0.1 | -0.3 | -0.4 | 0.2 |
| Reaction time num false alarms | 0.1 | 0.1 | 0.2 | -0.5 | 0.1 | -0.3 | -0.3 | -0.1 | -0.2 | -0.2 |
| Reaction time num false alarms AUC | 0.1 | 0.1 | 0.2 | -0.1 | 0.4 | -0.1 | -0.2 | -0.3 | -0.4 | 0.1 |
| Reaction time trials correct on left | 0.1 | 0.1 | 0.3 | 0.3 | 0.6 | 0.0 | 0.1 | -0.3 | -0.4 | 0.2 |
| Reaction time trials on left | 0.1 | 0.1 | 0.4 | 0.4 | 0.6 | 0.1 | 0.2 | -0.3 | -0.4 | 0.2 |
| Reaction time premature initiations | 0.1 | 0.2 | 0.4 | -0.6 | -0.2 | -0.7 | -0.5 | 0.2 | -0.1 | -0.5 |
| Std. dev. reaction times | 0.1 | 0.2 | 0.6 | 0.8 | 0.7 | -0.2 | 0.1 | -0.2 | -0.2 | 0.4 |
| Reaction time trials completed | 0.1 | 0.1 | 0.4 | 0.4 | 0.6 | 0.1 | 0.2 | -0.3 | -0.4 | 0.2 |
| Reaction time trials AUC | 0.1 | 0.2 | 0.5 | 0.4 | 0.7 | 0.1 | 0.3 | -0.4 | -0.5 | 0.3 |
| Condit. Reinf. active responses | 0.1 | 0.1 | 0.3 | -0.3 | -0.6 | 0.2 | 0.1 | -0.1 | -0.2 | 0.0 |
| Condit. Reinf. inactive responses | 0.1 | 0.2 | 0.7 | -0.5 | -0.9 | 0.1 | 0.2 | 0.0 | -0.0 | -0.2 |
| Condit. Reinf. lever reinforcers received | 0.1 | 0.1 | 0.5 | -0.4 | -0.7 | 0.1 | 0.1 | 0.0 | -0.1 | -0.0 |
| Pavlov. Cond. change in total contacts | 0.1 | 0.2 | 0.4 | 0.6 | 0.3 | 0.3 | 0.5 | -0.2 | -0.2 | 0.5 |
| Pavlov. Cond. response bias | 0.1 | 0.2 | 0.5 | 0.7 | 0.3 | 0.3 | 0.4 | -0.1 | -0.1 | 0.6 |
| Intermittent access day 1 total infusions | 0.1 | 0.1 | 0.2 | -0.1 | -0.2 | -0.3 | -0.4 | 0.4 | 0.4 | -0.3 |
| Intermittent access day 15 total infusions | 0.1 | 0.1 | 0.3 | -0.1 | -0.3 | 0.4 | 0.6 | -0.0 | -0.1 | 0.1 |
| Intermittent access terminal intake (last 3 days) | 0.1 | 0.2 | 0.3 | -0.5 | -0.5 | 0.4 | 0.5 | 0.0 | -0.2 | -0.2 |
| Intermittent access day 1 locomotion | 0.1 | 0.1 | 0.1 | -0.1 | -0.3 | -0.2 | -0.2 | 0.3 | 0.4 | -0.2 |
| Intermittent access total locomotion | 0.1 | 0.1 | 0.1 | 0.4 | 0.3 | 0.3 | 0.3 | -0.2 | -0.2 | 0.3 |
| Intermittent access standard deviation | 0.1 | 0.1 | 0.3 | -0.4 | -0.5 | 0.6 | 0.5 | -0.1 | -0.2 | -0.2 |
| Post-drug Anxiety | 0.1 | 0.1 | 0.2 | -0.3 | 0.2 | -0.5 | -0.3 | 0.1 | -0.0 | -0.2 |
| Incentive Sensitization - Responses | 0.1 | 0.1 | 0.2 | 0.2 | 0.3 | 0.2 | 0.2 | -0.3 | -0.4 | 0.1 |
| Incentive Sensitization - Breakpoint | 0.1 | 0.1 | 0.2 | 0.2 | 0.2 | 0.3 | 0.3 | -0.3 | -0.4 | 0.1 |
| Short access total infusions | 0.1 | 0.1 | 0.2 | 0.5 | 0.5 | -0.2 | -0.4 | 0.1 | 0.1 | 0.3 |
| Short access day 10 total locomotion | 0.1 | 0.1 | 0.3 | 0.4 | 0.6 | 0.0 | 0.1 | -0.2 | -0.2 | 0.3 |
| One hour access (shock baseline) | 0.1 | 0.1 | 0.3 | -0.1 | 0.0 | 0.5 | 0.6 | -0.3 | -0.5 | 0.1 |
| Locomotion distance, session 1 | 0.1 | 0.2 | 0.4 | -0.6 | -0.7 | -0.2 | -0.3 | 0.4 | 0.3 | -0.4 |
| Locomotion velocity, session 2 | 0.1 | 0.1 | 0.3 | -0.2 | -0.5 | 0.1 | -0.1 | 0.1 | 0.2 | -0.4 |
| Degree of sensitization stereotypy | 0.1 | 0.1 | 0.3 | 0.2 | 0.1 | -0.5 | -0.4 | 0.5 | 0.5 | -0.1 |
| Condit. Reinf. active responses | 0.1 | 0.1 | 0.1 | -0.3 | 0.0 | -0.3 | -0.4 | 0.2 | 0.3 | -0.2 |
| Time in familiar zone, hab. session 1 | 0.1 | 0.1 | 0.5 | -0.4 | -0.7 | -0.1 | -0.1 | 0.3 | 0.3 | -0.3 |
| Total zone transitions, hab. session 1 | 0.1 | 0.2 | 0.3 | -0.5 | -0.6 | -0.4 | -0.3 | 0.4 | 0.3 | -0.3 |
| Total zone transitions, hab. session 2 | 0.1 | 0.1 | 0.3 | -0.3 | -0.3 | -0.4 | -0.1 | 0.6 | 0.3 | -0.0 |
| Novel to familiar place preference ratio | 0.1 | 0.1 | 0.1 | -0.3 | 0.1 | 0.1 | -0.0 | -0.4 | -0.3 | -0.1 |
| Novelty place preference | 0.1 | 0.1 | 0.3 | -0.0 | 0.4 | 0.3 | 0.0 | -0.5 | -0.5 | 0.1 |
| Time in novel zone, NPP test | 0.1 | 0.1 | 0.2 | -0.2 | 0.3 | 0.2 | -0.1 | -0.5 | -0.4 | -0.1 |
| Locomotion velocity, NPP test | 0.1 | 0.1 | 0.3 | -0.1 | -0.5 | -0.2 | -0.2 | 0.5 | 0.5 | -0.2 |
| Pavlov. Cond. magazine entry latency | 0.1 | 0.1 | 0.1 | -0.2 | -0.3 | -0.3 | -0.4 | 0.3 | 0.4 | -0.2 |
| Pavlov. Cond. latency score | 0.1 | 0.1 | 0.4 | -0.6 | -0.4 | -0.3 | -0.1 | 0.1 | -0.0 | -0.4 |
| Pavlov. Cond. magazine entry number | 0.1 | 0.1 | 0.2 | -0.3 | -0.4 | -0.0 | -0.1 | 0.3 | 0.3 | -0.2 |
| Pavlov. Cond. lever-magazine prob. diff. | 0.1 | 0.1 | 0.3 | -0.6 | -0.5 | -0.3 | -0.2 | 0.1 | -0.0 | -0.3 |
| Pavlov. Cond. response bias | 0.1 | 0.2 | 0.4 | -0.6 | -0.5 | -0.4 | -0.3 | 0.2 | 0.2 | -0.4 |
| Bone surface | 0.1 | 0.2 | 0.4 | 0.3 | -0.0 | 0.7 | 0.7 | -0.5 | -0.5 | 0.2 |
| Bone: cortical area | 0.1 | 0.2 | 0.5 | -0.7 | -0.5 | -0.3 | -0.0 | 0.3 | 0.1 | -0.7 |
| Bone: elastic displacement | 0.1 | 0.2 | 0.5 | 0.7 | 0.3 | 0.3 | 0.3 | 0.1 | 0.1 | 0.6 |
| Bone: post-yield work | 0.1 | 0.2 | 0.5 | -0.5 | -0.5 | -0.2 | -0.2 | 0.1 | 0.2 | -0.7 |
| Bone: trabecular spacing | 0.1 | 0.1 | 0.3 | 0.0 | 0.6 | -0.3 | -0.1 | -0.2 | -0.2 | 0.0 |
| Breakpoint value in progressive ratio session | 0.1 | 0.1 | 0.2 | -0.4 | -0.2 | -0.1 | -0.3 | 0.1 | 0.1 | -0.1 |
| Delta ambulatory time before/after self-admin | 0.1 | 0.1 | 0.3 | -0.3 | -0.5 | 0.3 | 0.1 | 0.1 | 0.1 | -0.0 |
| Time in closed arm after self-admin | 0.1 | 0.1 | 0.5 | 0.4 | 0.3 | 0.3 | 0.7 | -0.3 | -0.3 | 0.2 |
| Area under the delay curve | 0.1 | 0.1 | 0.3 | 0.1 | 0.2 | -0.1 | 0.1 | -0.3 | -0.6 | 0.1 |
| Delay disc. indifference point, 0s delay | 0.1 | 0.1 | 0.1 | 0.3 | 0.3 | 0.1 | 0.0 | -0.2 | -0.4 | 0.3 |
| Delay discount hyperbolic model param | 0.1 | 0.1 | 0.2 | 0.4 | 0.3 | 0.3 | 0.2 | -0.1 | 0.2 | 0.3 |
| Change in fecal boli incidents, locomotor task | 0.1 | 0.1 | 0.2 | 0.4 | 0.1 | 0.4 | 0.2 | -0.4 | -0.4 | 0.3 |
| Time >=10cm from walls, locomotor time 2 | 0.1 | 0.1 | 0.3 | 0.6 | 0.3 | -0.1 | -0.3 | 0.1 | 0.2 | 0.3 |
| Bouts of movement, locomotor time 2 | 0.1 | 0.1 | 0.2 | -0.4 | -0.5 | -0.4 | -0.5 | 0.3 | 0.3 | -0.3 |
| Total resting periods, locomotor time 2 | 0.1 | 0.1 | 0.1 | -0.3 | -0.3 | -0.2 | -0.3 | 0.2 | 0.2 | -0.1 |
| Food seeking constrained by brief footshock | 0.1 | 0.1 | 0.2 | 0.4 | 0.4 | -0.3 | -0.5 | 0.2 | 0.4 | -0.0 |
| Latency to leave start box in cocaine runway, M | 0.1 | 0.1 | 0.4 | 0.3 | 0.3 | -0.6 | -0.5 | 0.2 | 0.2 | 0.0 |
| Co content in liver | 0.1 | 0.1 | 0.2 | -0.4 | -0.4 | -0.1 | 0.0 | 0.1 | 0.3 | -0.1 |
| Light reinforcement 2 | 0.0 | 0.0 | 0.1 | 0.1 | 0.3 | -0.3 | -0.2 | 0.2 | 0.1 | 0.2 |
| Reaction time false alarm rate | 0.0 | 0.0 | 0.1 | -0.3 | 0.1 | 0.0 | -0.1 | -0.2 | -0.2 | 0.1 |
| Cocaine response before conditioning | 0.0 | 0.0 | 0.1 | 0.4 | 0.1 | 0.1 | 0.2 | -0.1 | -0.1 | 0.3 |
| Condit. Reinf. active minus inactive responses | 0.0 | 0.0 | 0.1 | -0.2 | -0.3 | 0.0 | -0.1 | -0.0 | -0.1 | 0.1 |
| Pavlov. Cond. lever latency | 0.0 | 0.0 | 0.0 | -0.2 | -0.0 | -0.1 | -0.1 | -0.1 | -0.1 | -0.1 |
| Pavlov. Cond. lever contacts | 0.0 | 0.0 | 0.1 | 0.1 | -0.2 | 0.0 | 0.1 | 0.2 | 0.2 | 0.1 |
| Conditioned locomotion | 0.0 | 0.0 | 0.1 | -0.1 | -0.1 | 0.2 | 0.3 | 0.0 | 0.1 | -0.0 |
| Intermittent access total infusions | 0.0 | 0.0 | 0.0 | -0.2 | -0.2 | 0.1 | 0.0 | 0.2 | 0.0 | -0.2 |
| Intermittent access day 15 total locomotion | 0.0 | 0.0 | 0.1 | 0.0 | -0.1 | 0.3 | 0.3 | 0.1 | 0.0 | -0.1 |
| Cocaine induced anxiety | 0.0 | 0.0 | 0.1 | 0.1 | 0.3 | 0.1 | 0.1 | -0.2 | -0.2 | 0.1 |
| Lifetime Intake | 0.0 | 0.0 | 0.0 | -0.0 | 0.0 | -0.1 | -0.2 | 0.2 | 0.1 | -0.0 |
| Progressive ratio test 1 active lever presses | 0.0 | 0.0 | 0.0 | 0.0 | 0.2 | -0.0 | 0.2 | -0.0 | -0.1 | 0.1 |
| Progressive ratio test 1 breakpoint | 0.0 | 0.0 | 0.1 | 0.2 | 0.3 | 0.1 | 0.3 | -0.1 | -0.2 | 0.1 |
| Progressive ratio test 2 active lever presses | 0.0 | 0.0 | 0.1 | -0.2 | -0.0 | -0.2 | -0.2 | 0.2 | 0.0 | -0.2 |
| Progressive ratio test 2 breakpoint | 0.0 | 0.0 | 0.0 | -0.1 | 0.1 | -0.1 | 0.0 | 0.0 | -0.2 | -0.2 |
| Short access day 1 locomotion | 0.0 | 0.0 | 0.1 | 0.3 | 0.2 | 0.2 | 0.1 | -0.1 | 0.0 | 0.1 |
| Locomotion distance, session 2 | 0.0 | 0.1 | 0.3 | -0.4 | -0.5 | 0.1 | 0.1 | 0.1 | -0.1 | -0.1 |
| Locomotion velocity, session 8 | 0.0 | 0.0 | 0.2 | 0.1 | -0.5 | 0.1 | 0.0 | 0.2 | 0.1 | -0.1 |
| Incentive salience index mean | 0.0 | 0.0 | 0.1 | 0.1 | 0.4 | 0.0 | -0.0 | -0.1 | 0.0 | 0.1 |
| Condit. Reinf. lever presses | 0.0 | 0.0 | 0.1 | -0.2 | -0.1 | -0.1 | -0.2 | 0.3 | 0.3 | -0.0 |
| Total zone transitions, NPP test | 0.0 | 0.0 | 0.1 | -0.1 | -0.1 | -0.3 | -0.2 | 0.2 | -0.0 | 0.0 |
| Pavlov. Cond. change in total contacts | 0.0 | 0.0 | 0.1 | -0.3 | -0.1 | -0.1 | 0.1 | -0.1 | -0.2 | -0.1 |
| Pavlov. Cond. index score | 0.0 | 0.1 | 0.2 | -0.5 | -0.3 | -0.2 | -0.1 | -0.0 | -0.1 | -0.2 |
| Bone volume | 0.0 | 0.1 | 0.1 | -0.2 | -0.3 | 0.3 | 0.3 | -0.2 | -0.3 | -0.1 |
| Bone: final force | 0.0 | 0.1 | 0.1 | -0.3 | -0.3 | 0.1 | 0.3 | -0.1 | -0.2 | -0.4 |
| Bone: final moment | 0.0 | 0.1 | 0.2 | -0.3 | -0.2 | 0.1 | 0.2 | 0.1 | -0.0 | -0.5 |
| Bone: trabecular thickness | 0.0 | 0.1 | 0.2 | -0.3 | -0.5 | 0.1 | -0.1 | 0.2 | 0.2 | -0.2 |
| Diff in mean of infusions in LGA sessions | 0.0 | 0.0 | 0.0 | 0.1 | 0.0 | -0.0 | 0.0 | 0.1 | -0.0 | 0.1 |
| Delta time to tail flick, vehicle, before/after SA | 0.0 | 0.0 | 0.1 | -0.1 | -0.3 | 0.2 | 0.3 | 0.0 | 0.0 | -0.2 |
| Delay discount exponential model param | 0.0 | 0.0 | 0.2 | 0.1 | -0.1 | 0.2 | 0.0 | 0.1 | 0.4 | -0.0 |
| Locomotion in novel chamber | 0.0 | 0.0 | 0.1 | -0.2 | 0.0 | -0.1 | -0.3 | 0.1 | 0.1 | -0.4 |
| Se content in liver | 0.0 | 0.0 | 0.1 | -0.2 | -0.1 | -0.1 | 0.1 | -0.1 | -0.3 | -0.1 |
For each tested trait, stats based on TWAS chi2 (squared Z-score) for the above models are shown. Avg chi2 ratio is the mean chi2 across all models for this gene, divided by the mean chi2 across all models for all genes. Avg chi2 is the mean chi2 across all models for this gene. Max chi2 is the highest chi2 across all models for this gene.
The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.