Hub : Genes

Rac3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression ENSRNOG00000069600 0.04 0.03 2.2e-05 0.02 0.04 0.04 0.04 1.3e-03 9.0e-06 2.8e-05 5.9e-05
2 BLA alternative TSS ENSRNOT00000073886 0.07 0.06 6.3e-03 0.03 0.03 0.01 0.03 6.0e-03 1.6e-02 8.7e-02 1.3e-02
3 BLA alternative TSS ENSRNOT00000082551 0.07 0.05 7.7e-03 0.03 0.02 0.01 0.03 6.8e-03 2.0e-02 9.8e-02 1.5e-02
4 BLA isoform ratio ENSRNOT00000073886 0.11 0.1 3.9e-03 0.01 0.02 0.03 0.01 5.8e-02 3.4e-02 1.1e-02 6.7e-02
5 BLA isoform ratio ENSRNOT00000082551 0.1 0.09 6.2e-03 0.01 0.01 0.02 0.01 8.6e-02 7.8e-02 2.5e-02 1.3e-01
6 Brain alternative TSS ENSRNOT00000073886 0.06 0.04 4.2e-05 0.06 0.05 0.04 0.04 5.5e-06 2.1e-05 1.3e-04 5.4e-05
7 Brain alternative TSS ENSRNOT00000082551 0.05 0.04 6.2e-05 0.05 0.05 0.04 0.04 2.7e-05 3.0e-05 1.8e-04 7.2e-05
8 LHb mRNA stability ENSRNOG00000069600 0.22 0.13 5.5e-03 0.01 0.08 0.04 0.03 1.6e-01 6.4e-03 3.7e-02 7.8e-02
9 Liver alternative TSS ENSRNOT00000073886 0.33 0.14 0.0e+00 0.23 0.24 0.24 0.23 5.4e-25 6.6e-26 2.7e-26 1.3e-25
10 Liver alternative TSS ENSRNOT00000082551 0.33 0.14 0.0e+00 0.22 0.23 0.24 0.23 1.7e-24 2.3e-25 7.2e-26 4.5e-25
11 Liver gene expression ENSRNOG00000069600 0.4 0.15 0.0e+00 0.33 0.36 0.36 0.36 6.3e-38 6.5e-41 6.3e-41 8.7e-42
12 Liver isoform ratio ENSRNOT00000073886 0.02 0.02 4.1e-03 0.03 0.02 0.02 0.02 6.4e-04 2.4e-03 2.0e-03 1.6e-03
13 Liver mRNA stability ENSRNOG00000069600 0.29 0.14 0.0e+00 0.25 0.23 0.25 0.24 2.4e-27 1.3e-25 6.6e-28 9.4e-27
14 PL alternative TSS ENSRNOT00000073886 0.61 0.16 2.0e-04 0.04 0.04 0.04 0.04 4.0e-04 1.1e-03 6.0e-04 4.3e-04
15 PL alternative TSS ENSRNOT00000082551 0.5 0.19 5.4e-04 0.04 0.03 0.03 0.03 5.7e-04 1.9e-03 3.1e-03 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
BMI with tail0.00.20.40.6-0.20.20.4-0.4-0.30.30.30.2-0.20.3-0.3-0.6-0.70.7
BMI without tail0.40.94.62.2-0.50.51.0-0.9-0.50.50.51.2-1.20.6-0.3-1.3-0.50.5
Body weight1.35.311.13.3-2.32.3-1.01.1-2.62.6-1.52.1-2.12.3-2.9-2.8-2.12.1
Epididymis fat weight0.10.10.90.9-0.40.40.3-0.3-0.30.30.10.1-0.10.1-0.6-0.40.0-0.0
Glucose1.11.86.2-0.3-1.31.3-2.52.4-0.90.9-1.90.5-0.51.1-0.9-0.4-1.21.2
Heart weight0.50.82.40.8-0.80.8-0.50.5-0.60.6-0.51.1-1.00.7-0.4-0.8-1.61.6
Left kidney weight0.20.51.30.3-0.40.4-0.50.5-0.80.8-0.60.6-0.60.7-1.0-0.8-1.11.1
Right kidney weight0.00.00.1-0.30.1-0.10.1-0.10.0-0.00.1-0.10.1-0.0-0.2-0.3-0.30.3
Tail length1.13.211.53.4-1.71.7-0.20.2-1.81.8-0.82.2-2.21.8-1.8-2.4-1.01.0
Length with tail1.34.98.72.9-2.32.3-1.51.6-2.62.6-2.01.8-1.82.4-3.0-2.5-1.41.4
Length without tail0.81.73.80.2-1.31.3-1.91.8-1.51.5-1.70.2-0.31.2-2.0-0.9-0.90.9
Liver weight, left0.50.91.60.4-1.01.0-1.31.3-0.90.9-1.10.8-0.80.9-0.8-0.6-1.01.0
Liver weight, right0.81.43.01.5-1.11.1-0.60.6-1.41.4-0.90.9-0.91.4-1.7-1.3-1.11.1
Parametrial fat weight0.81.63.01.7-1.21.2-0.70.7-1.41.4-1.01.2-1.21.4-1.4-1.7-1.21.2
Retroperitoneal fat weight1.44.711.73.4-2.22.2-0.91.0-2.42.4-1.72.3-2.32.0-2.4-2.3-1.91.9
Intraocular pressure0.10.10.60.8-0.40.40.0-0.0-0.20.2-0.10.5-0.50.4-0.3-0.40.0-0.0
Extensor digitorum longus weight0.41.43.1-0.61.2-1.21.8-1.71.1-1.11.6-0.90.9-1.11.30.61.2-1.2
Soleus weight0.41.12.91.7-1.01.0-0.30.3-1.11.1-0.61.1-1.11.1-1.1-1.1-1.11.1
Tibialis anterior weight0.10.30.8-0.20.6-0.60.9-0.90.5-0.50.8-0.30.3-0.50.70.30.6-0.6
Tibia length7.922.229.25.4-4.94.9-3.94.0-5.15.1-4.33.9-3.95.0-5.1-5.2-4.84.8
Number of licking bursts0.20.20.6-0.10.5-0.50.8-0.80.4-0.40.6-0.20.3-0.30.30.10.5-0.5
Food consumed during 24 hour testing period0.10.10.40.6-0.20.2-0.10.1-0.30.3-0.30.1-0.10.4-0.5-0.1-0.20.2
Times rat made contact with spout3.23.74.41.8-1.81.8-1.81.8-1.91.9-2.02.0-2.01.9-2.0-1.7-2.12.1
Mean time between licks in bursts1.21.72.6-1.61.4-1.41.0-1.01.3-1.31.2-1.31.3-1.31.51.21.4-1.4
Mean num. licks in bursts1.51.92.41.1-1.41.4-1.61.6-1.31.3-1.51.3-1.31.2-1.3-0.9-1.51.5
Std. dev. time between licks in bursts2.02.44.5-0.51.4-1.42.1-2.11.5-1.51.9-1.31.3-1.41.51.21.7-1.7
Water consumed over 24 hours0.40.50.90.3-0.50.5-0.80.8-0.70.7-0.90.5-0.50.8-0.9-0.5-0.70.7
Indifference point 0 sec0.10.10.20.3-0.30.3-0.20.2-0.50.5-0.30.3-0.40.1-0.1-0.4-0.10.1
Indifference point AUC0.00.00.30.00.0-0.00.0-0.00.1-0.10.20.2-0.2-0.20.5-0.2-0.20.2
Indifference point function ln k0.91.22.3-1.31.0-1.00.8-0.80.8-0.80.9-1.51.5-0.80.81.31.4-1.4
Indifference point function log k0.91.22.3-1.31.0-1.00.8-0.80.8-0.80.9-1.51.5-0.80.81.31.4-1.4
Delay discounting total patch changes 0 sec0.00.00.10.3-0.20.2-0.10.1-0.30.3-0.10.1-0.10.0-0.0-0.30.1-0.1
Delay discounting total patch changes 12 sec0.30.30.80.4-0.40.4-0.50.5-0.60.6-0.50.8-0.80.40.0-0.9-0.70.7
Delay discounting total patch changes 18 sec0.40.52.2-0.50.6-0.60.7-0.70.6-0.60.8-0.40.3-0.81.50.30.8-0.8
Delay discounting total patch changes 24 sec0.20.20.50.7-0.40.4-0.10.2-0.50.5-0.30.5-0.50.2-0.3-0.4-0.50.5
Delay discounting total patch changes 6 sec0.50.71.10.9-0.80.8-0.70.7-1.11.1-0.80.9-0.90.6-0.9-1.0-0.80.8
Delay discounting time to switch 0 sec0.10.20.5-0.70.6-0.60.3-0.30.4-0.40.2-0.40.4-0.30.20.30.6-0.6
Delay discounting water rate 0 sec0.40.62.21.5-1.01.0-0.20.2-0.70.7-0.30.7-0.70.8-0.6-0.9-0.50.5
Delay discounting water rate 12 sec0.20.30.7-0.10.3-0.30.7-0.70.7-0.70.8-0.50.4-0.50.70.40.4-0.4
Delay discounting water rate 18 sec0.30.41.10.00.6-0.61.0-1.00.5-0.50.9-0.70.7-0.50.20.50.6-0.6
Delay discounting water rate 24 sec0.20.20.90.60.1-0.11.0-0.90.5-0.50.8-0.00.0-0.40.40.20.0-0.0
Delay discounting water rate 6 sec0.20.30.7-0.20.4-0.40.6-0.60.5-0.50.7-0.80.8-0.30.40.30.6-0.6
Locomotor activity0.20.30.9-1.00.7-0.70.3-0.40.6-0.60.4-0.50.5-0.70.40.80.3-0.3
Locomotor testing distance1.01.72.6-1.51.4-1.41.1-1.11.3-1.31.1-1.41.4-1.40.71.61.3-1.3
Locomotor testing rearing0.50.81.4-0.91.0-1.00.9-0.91.0-1.00.8-0.50.5-0.90.81.20.9-0.9
Light reinforcement 10.10.21.10.50.2-0.21.0-1.00.4-0.40.7-0.10.1-0.40.30.30.2-0.2
Light reinforcement 20.20.21.21.1-0.50.50.3-0.3-0.50.5-0.10.4-0.40.4-0.7-0.2-0.30.3
Reaction time number correct4.05.89.4-1.42.3-2.33.1-3.02.6-2.62.9-1.91.9-2.32.72.02.3-2.3
Reaction time mean minus median0.30.30.70.2-0.60.6-0.80.8-0.60.6-0.80.6-0.60.4-0.4-0.2-0.50.5
Reaction time mean minus median AUC0.00.10.10.1-0.30.3-0.30.3-0.20.2-0.30.3-0.30.2-0.1-0.0-0.10.1
Reaction time num false alarms0.10.10.2-0.50.4-0.40.2-0.20.4-0.40.2-0.10.2-0.40.30.5-0.00.0
Reaction time num false alarms AUC0.40.61.0-1.00.9-0.90.6-0.60.9-0.90.7-0.60.7-0.80.71.00.5-0.5
Reaction time trials correct on left4.05.89.4-1.42.3-2.33.1-3.02.6-2.62.9-1.91.9-2.32.72.02.3-2.3
Reaction time trials on left4.26.09.8-1.42.4-2.43.1-3.12.7-2.73.0-1.91.9-2.32.72.02.3-2.3
Reaction time mean0.10.10.50.4-0.40.4-0.10.1-0.20.2-0.10.7-0.70.20.1-0.4-0.40.4
Reaction time mean AUC0.10.10.20.10.1-0.10.5-0.50.2-0.20.40.3-0.3-0.30.40.1-0.00.0
Median of all reaction times0.00.10.20.3-0.10.10.3-0.20.0-0.00.20.4-0.4-0.00.3-0.3-0.20.2
Reaction time omissions0.10.20.4-0.10.4-0.40.6-0.60.3-0.30.40.00.0-0.70.30.60.3-0.3
Reaction time false alarm rate0.30.41.0-0.1-0.30.3-1.01.0-0.50.5-0.90.5-0.40.4-0.7-0.2-0.80.8
Reaction time premature initiation rate0.40.61.1-1.10.8-0.80.3-0.30.8-0.80.5-0.90.9-0.90.50.90.6-0.6
Reaction time premature initiations2.53.64.4-1.61.9-1.91.9-1.92.1-2.12.0-1.81.8-2.02.01.81.8-1.8
Std. dev. reaction times0.10.20.7-0.60.3-0.30.2-0.20.5-0.50.3-0.00.1-0.60.90.60.2-0.2
Reaction time trials completed4.26.09.8-1.42.4-2.43.1-3.12.7-2.73.0-1.91.9-2.32.72.02.3-2.3
Reaction time trials AUC4.05.79.5-1.32.3-2.33.1-3.12.6-2.63.0-1.81.8-2.32.71.92.2-2.2
Social response proportion0.70.81.2-0.90.9-0.90.7-0.80.9-0.90.9-0.90.9-0.80.90.61.1-1.1
Social responses0.70.91.6-0.81.0-1.00.9-0.90.6-0.60.8-1.31.3-0.80.50.71.2-1.2
Social time0.40.60.9-0.70.9-0.90.8-0.80.6-0.60.8-0.90.9-0.60.50.90.7-0.7
Conditioned locomotion0.50.52.81.7-0.70.70.2-0.1-0.70.7-0.20.7-0.70.7-0.7-0.8-0.40.4
Cocaine response after cond. corrected0.20.20.50.2-0.40.4-0.70.7-0.50.5-0.60.2-0.20.4-0.6-0.5-0.20.2
Cocaine response after cond. not corrected0.10.10.2-0.40.1-0.1-0.30.30.0-0.0-0.2-0.30.30.0-0.10.10.4-0.4
Cocaine response before conditioning1.41.72.1-1.31.4-1.41.1-1.21.2-1.21.2-1.41.4-1.21.31.51.4-1.4
Saline control response1.11.43.51.9-1.21.2-0.60.6-1.31.3-0.91.3-1.31.3-1.6-1.2-0.90.9
Condit. Reinf. active minus inactive responses0.30.40.80.9-0.70.7-0.30.4-0.30.3-0.20.7-0.70.6-0.4-0.8-0.80.8
Condit. Reinf. active-inactive response ratio2.22.33.01.7-1.61.6-1.21.2-1.31.3-1.21.6-1.61.6-1.6-1.7-1.71.7
Condit. Reinf. active responses0.00.10.10.4-0.20.20.1-0.00.2-0.20.20.2-0.20.10.3-0.3-0.30.3
Condit. Reinf. inactive responses0.60.81.7-0.90.7-0.70.7-0.71.0-1.00.9-0.90.9-0.81.30.80.9-0.9
Condit. Reinf. lever presses0.10.10.30.10.2-0.20.5-0.50.4-0.40.5-0.30.3-0.20.50.10.3-0.3
Condit. Reinf. lever reinforcers received0.00.10.20.2-0.10.10.3-0.30.4-0.40.40.0-0.1-0.10.5-0.1-0.10.1
Pavlov. Cond. lever latency0.10.20.6-0.3-0.20.2-0.70.7-0.40.4-0.60.1-0.10.3-0.7-0.1-0.10.1
Pavlov. Cond. magazine entry latency3.03.45.0-1.81.9-1.91.8-1.81.9-1.91.9-1.81.8-1.82.21.91.7-1.7
Pavlov. Cond. change in total contacts0.70.91.8-0.80.9-0.91.1-1.11.1-1.11.1-0.80.8-1.11.40.90.7-0.7
Pavlov. Cond. index score0.71.01.8-0.71.0-1.01.1-1.11.0-1.01.1-0.90.9-1.01.30.90.8-0.8
Pavlov. Cond. latency score0.91.12.0-0.71.1-1.11.2-1.21.1-1.11.2-0.90.9-1.11.41.00.9-0.9
Pavlov. Cond. lever contacts0.20.20.70.40.2-0.20.8-0.80.4-0.40.70.0-0.0-0.40.90.10.2-0.2
Pavlov. Cond. magazine entry number2.63.24.31.6-1.81.8-1.81.8-1.71.7-1.81.8-1.81.8-2.1-1.8-1.81.8
Pavlov. Cond. intertrial magazine entries0.81.02.11.4-1.11.1-0.60.6-0.70.7-0.61.1-1.10.9-1.1-1.1-1.11.1
Pavlov. Cond. lever-magazine prob. diff.0.91.12.0-0.81.1-1.11.2-1.21.1-1.11.2-1.01.0-1.11.41.00.9-0.9
Pavlov. Cond. response bias0.40.61.5-0.30.6-0.61.0-0.90.8-0.80.9-0.50.5-0.71.20.60.6-0.6
Conditioned reinforcement - actives0.60.61.0-0.40.8-0.80.9-0.90.8-0.80.8-0.90.9-0.80.30.41.0-1.0
Conditioned reinforcement - inactives1.01.11.91.3-1.11.1-0.80.9-1.11.1-0.90.9-0.91.1-1.4-1.3-0.80.8
Conditioned locomotion0.10.10.3-0.00.2-0.20.4-0.40.2-0.20.2-0.20.2-0.2-0.5-0.10.3-0.3
Intermittent access intake day 1-15 change0.80.81.51.2-1.01.0-0.80.8-1.11.1-0.90.8-0.81.1-0.8-1.0-0.40.4
Intermittent access intake escalation0.40.41.01.0-0.70.7-0.40.5-0.80.8-0.60.5-0.50.8-0.6-0.70.1-0.1
Intermittent access intake escalation 23.53.54.81.9-2.02.0-1.71.7-2.02.0-1.81.8-1.92.0-2.2-1.7-1.61.6
Intermitt. access day 1 inactive lever presses1.31.42.01.3-1.31.3-1.11.1-1.41.4-1.20.8-0.81.4-1.4-1.4-0.40.4
Intermitt. access day 15 inactive lever presses0.10.10.40.6-0.20.20.3-0.2-0.10.10.10.3-0.20.1-0.3-0.1-0.20.2
Intermitt. access escalation Index0.40.30.80.20.5-0.50.9-0.90.6-0.60.7-0.30.3-0.60.40.30.8-0.8
Intermittent access day 1 total infusions0.10.10.70.5-0.30.3-0.10.1-0.30.3-0.10.3-0.30.3-0.1-0.9-0.10.1
Intermittent access day 15 total infusions0.10.20.60.8-0.40.4-0.10.1-0.40.4-0.20.3-0.30.4-0.4-0.8-0.00.0
Intermittent access terminal intake (last 3 days)0.60.71.71.2-0.90.9-0.50.5-0.80.8-0.70.8-0.80.8-0.9-1.3-0.50.5
Intermittent access total infusions0.10.10.70.7-0.30.3-0.00.1-0.30.3-0.10.1-0.10.3-0.2-0.80.3-0.3
Intermittent access day 1 locomotion0.20.20.70.20.1-0.10.4-0.30.1-0.10.3-0.60.6-0.1-0.3-0.20.8-0.8
Intermittent access day 15 total locomotion0.40.51.40.8-0.60.6-0.50.5-0.70.7-0.60.6-0.60.7-1.0-1.2-0.10.1
Intermittent access total locomotion0.20.20.60.6-0.40.4-0.20.2-0.40.4-0.2-0.10.10.4-0.8-0.80.5-0.5
Intermittent access standard deviation0.90.91.90.3-1.11.1-1.41.4-1.11.1-1.20.4-0.51.1-1.3-0.5-0.50.5
Cocaine induced anxiety8.810.111.93.0-3.43.4-3.03.0-3.43.4-3.12.9-3.03.4-3.0-2.9-3.23.2
Post-drug Anxiety2.12.32.91.2-1.71.7-1.71.7-1.71.7-1.61.1-1.11.7-1.3-1.4-1.51.5
Baseline Anxiety7.88.310.2-3.23.0-3.02.2-2.23.1-3.12.5-3.23.2-3.12.72.82.9-2.9
Lifetime Intake0.00.00.30.3-0.10.10.1-0.1-0.10.10.0-0.10.10.1-0.0-0.50.3-0.3
Incentive Sensitization - Responses0.20.20.40.6-0.30.3-0.30.3-0.40.4-0.30.4-0.40.4-0.5-0.6-0.40.4
Incentive Sensitization - Breakpoint0.20.20.50.6-0.40.4-0.30.3-0.40.4-0.30.4-0.40.4-0.5-0.7-0.50.5
Progressive ratio test 1 active lever presses0.20.20.80.9-0.50.5-0.00.1-0.50.5-0.30.4-0.40.5-0.4-0.8-0.00.0
Progressive ratio test 1 breakpoint0.40.41.31.1-0.70.7-0.20.2-0.60.6-0.40.6-0.60.6-0.3-1.0-0.30.3
Progressive ratio test 1 inactive lever presses0.50.61.81.3-0.80.8-0.20.2-0.80.8-0.40.7-0.70.8-0.6-1.1-0.50.5
Progressive ratio test 2 active lever presses0.20.20.60.7-0.50.5-0.30.3-0.40.4-0.30.3-0.30.4-0.8-0.8-0.20.2
Progressive ratio test 2 breakpoint0.10.10.40.6-0.20.20.1-0.0-0.20.2-0.00.1-0.10.2-0.5-0.60.0-0.0
Progressive ratio test 2 inactive lever presses0.40.51.10.8-0.70.7-0.60.6-0.70.7-0.60.7-0.70.7-1.1-0.9-0.50.5
Total sessions with >9 infusions0.50.50.9-0.70.7-0.70.6-0.60.7-0.70.6-0.90.9-0.70.70.20.8-0.8
Short access day 1 total inactive lever presses1.01.11.7-0.71.2-1.21.3-1.31.2-1.21.2-0.70.7-1.20.41.01.0-1.0
Short access day 10 total inactive lever presses2.52.74.42.1-1.81.8-1.31.3-1.91.9-1.41.6-1.61.9-1.6-1.5-1.51.5
Short access day 1 total infusions0.70.71.8-1.31.0-1.00.5-0.61.0-1.00.7-0.90.9-1.00.90.70.6-0.6
Short access day 10 total infusions0.60.72.40.9-0.80.8-0.60.6-0.90.9-0.70.8-0.80.9-0.7-1.6-0.50.5
Short access total infusions0.00.00.10.0-0.00.0-0.00.00.0-0.00.0-0.10.1-0.00.3-0.40.0-0.0
Short access day 1 locomotion0.10.10.2-0.40.0-0.0-0.30.3-0.00.0-0.10.1-0.10.00.0-0.4-0.40.4
Short access day 10 total locomotion0.40.51.00.2-0.70.7-1.01.0-0.70.7-0.80.3-0.30.7-1.0-0.9-0.20.2
Short access total locomotion0.10.10.2-0.3-0.10.1-0.40.4-0.10.1-0.2-0.30.30.1-0.2-0.30.1-0.1
Compulsive drug intake0.10.10.20.4-0.20.20.1-0.1-0.20.2-0.00.3-0.30.2-0.20.1-0.50.5
One hour access (0.3 mA shock)0.30.31.21.1-0.50.5-0.00.0-0.50.5-0.20.7-0.70.5-0.4-0.9-0.50.5
One hour access (shock baseline)0.10.20.50.10.3-0.30.5-0.50.3-0.30.4-0.40.4-0.30.1-0.10.7-0.7
Number of responses in last shaping day0.10.10.30.5-0.30.30.1-0.1-0.20.2-0.0-0.10.10.2-0.6-0.5-0.00.0
Context. condit. distance diff. score0.81.02.3-0.20.9-0.91.5-1.51.1-1.11.4-0.40.5-1.01.10.50.8-0.8
Locomotion velocity, session 10.20.20.8-0.8-0.10.1-0.90.80.0-0.0-0.50.0-0.00.10.00.0-0.50.5
Locomotion distance, session 13.54.55.4-2.32.2-2.21.8-1.92.1-2.12.1-2.32.3-2.12.22.02.1-2.1
Locomotion velocity, session 21.61.94.4-2.11.4-1.40.6-0.61.4-1.41.0-1.71.7-1.41.31.61.3-1.3
Locomotion distance, session 21.31.92.2-1.21.4-1.41.4-1.41.3-1.31.5-1.41.4-1.31.51.21.4-1.4
Locomotion velocity, session 30.20.31.3-1.10.5-0.5-0.10.10.4-0.40.1-0.70.7-0.40.40.50.5-0.5
Locomotion distance, session 31.51.63.5-1.91.3-1.30.7-0.71.2-1.21.0-1.51.5-1.31.21.31.2-1.2
Stereotopy head waving bouts, day 30.00.00.2-0.50.1-0.1-0.30.30.0-0.0-0.20.0-0.0-0.10.00.1-0.00.0
Stereotopy head waving duration, day 30.00.10.3-0.50.2-0.20.0-0.00.2-0.20.1-0.10.1-0.20.30.20.3-0.3
Locomotion velocity, session 70.80.81.5-1.00.9-0.90.7-0.70.8-0.80.7-1.21.2-0.90.70.81.1-1.1
Locomotion distance, session 74.45.66.6-2.42.3-2.32.2-2.22.4-2.42.3-2.42.4-2.42.62.22.4-2.4
Stereotopy head waving bouts, day 70.10.10.20.3-0.20.2-0.10.1-0.20.2-0.10.3-0.30.1-0.2-0.2-0.50.5
Stereotopy head waving duration, day 70.30.30.50.6-0.50.5-0.30.3-0.60.6-0.40.7-0.70.4-0.6-0.5-0.70.7
Locomotion velocity, session 81.92.32.9-1.31.4-1.41.5-1.51.6-1.61.7-1.61.6-1.61.71.41.3-1.3
Locomotion distance, session 82.84.27.2-1.12.0-2.02.7-2.72.1-2.12.6-1.61.6-2.12.21.61.8-1.8
Degree of sensitization distance0.10.10.30.40.1-0.10.6-0.60.4-0.40.50.1-0.1-0.20.50.10.2-0.2
Degree of sensitization stereotypy0.10.10.40.5-0.30.3-0.00.1-0.30.3-0.10.5-0.50.2-0.3-0.4-0.60.6
Condit. Reinf. active minus inactive responses0.80.82.11.5-0.90.9-0.40.4-0.80.8-0.60.8-0.81.0-1.1-1.0-1.11.1
Condit. Reinf. active-inactive response ratio0.30.30.80.9-0.60.6-0.20.3-0.60.6-0.40.3-0.30.6-0.8-0.7-0.60.6
Condit. Reinf. active responses1.21.54.12.0-1.21.2-0.40.5-1.11.1-0.71.3-1.21.2-1.3-1.3-1.41.4
Condit. Reinf. inactive responses0.40.51.21.1-0.60.6-0.20.3-0.50.5-0.40.9-0.90.6-0.6-0.7-0.80.8
Incentive salience index mean0.30.41.51.2-0.60.6-0.10.1-0.60.6-0.30.5-0.50.7-0.8-0.7-0.70.7
Condit. Reinf. lever presses0.40.50.9-0.40.8-0.80.9-0.90.6-0.60.8-0.70.7-0.60.60.60.7-0.7
Time in familiar zone, hab. session 10.30.30.60.3-0.50.5-0.70.7-0.30.3-0.50.4-0.40.5-0.4-0.3-0.80.8
Time in novel zone, hab. session 10.10.10.2-0.20.3-0.30.5-0.50.2-0.20.4-0.10.1-0.40.40.10.5-0.5
Total zone transitions, hab. session 10.40.60.9-0.90.8-0.80.7-0.80.8-0.80.8-0.70.7-0.70.90.70.6-0.6
Total locomotion distance, hab. session 10.20.30.8-0.30.6-0.60.9-0.90.4-0.40.7-0.40.5-0.60.50.40.3-0.3
Locomotion velocity, hab. session 10.20.30.8-0.30.7-0.70.9-0.90.4-0.40.7-0.50.5-0.60.50.40.3-0.3
Time in familiar zone, hab. session 20.30.30.4-0.60.6-0.60.6-0.60.6-0.60.6-0.40.4-0.60.50.40.4-0.4
Time in novel zone, hab. session 20.00.00.0-0.20.0-0.00.0-0.00.2-0.20.1-0.20.2-0.10.20.10.2-0.2
Total zone transitions, hab. session 22.12.73.9-1.21.7-1.71.9-1.91.7-1.72.0-1.51.5-1.61.81.41.4-1.4
Total locomotion distance, hab. session 21.11.53.4-0.51.3-1.31.8-1.81.2-1.21.7-0.90.9-1.21.20.90.9-0.9
Locomotion velocity, hab. session 20.81.12.8-0.21.0-1.01.7-1.60.9-0.91.5-0.70.7-1.01.00.70.7-0.7
Novel to familiar place preference ratio4.04.25.02.1-2.12.1-1.91.9-2.12.1-2.11.9-1.92.1-2.2-2.0-2.12.1
Novelty place preference4.14.35.02.1-2.22.2-2.02.0-2.12.1-2.11.9-1.92.2-2.2-2.0-2.12.1
Time in novel zone, NPP test3.13.23.81.9-1.91.9-1.71.7-1.81.8-1.81.7-1.71.9-1.9-1.7-1.91.9
Total zone transitions, NPP test3.44.96.3-1.72.2-2.22.5-2.52.2-2.22.5-2.12.1-2.22.32.02.2-2.2
Total locomotion distance, NPP test2.63.65.9-1.11.9-1.92.4-2.41.9-1.92.3-1.71.7-2.01.81.71.7-1.7
Locomotion velocity, NPP test1.42.13.7-0.71.4-1.41.9-1.91.4-1.41.8-1.31.3-1.51.31.31.3-1.3
Pavlov. Cond. lever latency2.63.34.1-1.61.8-1.81.9-1.92.0-2.02.0-1.61.7-1.92.01.71.7-1.7
Pavlov. Cond. magazine entry latency4.25.56.42.4-2.32.3-2.22.3-2.52.5-2.52.1-2.12.5-2.5-2.3-2.32.3
Pavlov. Cond. change in total contacts2.02.13.01.1-1.41.4-1.71.7-1.71.7-1.71.1-1.21.5-1.7-1.3-1.31.3
Pavlov. Cond. index score3.84.85.72.4-2.22.2-1.91.9-2.42.4-2.22.1-2.12.3-2.3-2.2-2.22.2
Pavlov. Cond. latency score3.74.85.62.2-2.12.1-2.02.0-2.42.4-2.32.1-2.12.3-2.3-2.1-2.22.2
Pavlov. Cond. lever contacts1.11.31.81.1-1.11.1-1.01.0-1.41.4-1.31.1-1.11.2-1.3-1.1-1.01.0
Pavlov. Cond. magazine entry number5.77.18.0-2.42.7-2.72.7-2.72.8-2.82.8-2.42.4-2.82.72.62.7-2.7
Pavlov. Cond. intertrial magazine entries0.20.30.70.00.4-0.40.8-0.80.6-0.60.8-0.30.4-0.50.40.30.3-0.3
Pavlov. Cond. lever-magazine prob. diff.4.05.06.02.4-2.22.2-1.91.9-2.52.5-2.32.1-2.12.4-2.4-2.2-2.22.2
Pavlov. Cond. response bias4.25.16.22.2-2.32.3-2.22.3-2.52.5-2.42.0-2.02.5-2.4-2.2-2.12.1
Bone: apparent density0.00.10.20.10.3-0.30.5-0.50.1-0.10.3-0.20.2-0.20.20.10.2-0.2
Bone surface0.10.20.50.6-0.30.3-0.20.2-0.60.6-0.40.5-0.50.4-0.5-0.7-0.20.2
Bone volume0.00.10.20.5-0.10.10.1-0.1-0.40.4-0.10.3-0.30.2-0.2-0.5-0.10.1
Bone: connectivity density0.50.81.2-0.50.9-0.91.1-1.10.9-0.91.0-0.80.8-0.90.80.80.9-0.9
Bone: cortical apparent density0.60.82.5-1.61.0-1.00.3-0.40.9-0.90.6-0.90.9-0.90.90.80.8-0.8
Bone: cortical area3.55.38.52.8-2.22.2-1.51.5-2.72.7-1.91.5-1.52.4-2.9-2.8-2.52.5
Bone: cortical porosity4.85.26.91.8-2.22.2-2.62.6-2.42.4-2.61.8-1.82.3-2.6-2.1-2.32.3
Bone: cortical porosity4.14.45.61.8-2.02.0-2.22.2-2.22.2-2.31.7-1.82.1-2.4-2.0-2.22.2
Bone: cortical thickness4.57.411.02.9-2.62.6-2.22.2-3.23.2-2.41.7-1.72.9-3.3-3.1-3.13.1
Bone: cortical thickness1.41.72.71.3-1.31.3-1.01.1-1.51.5-1.10.6-0.61.3-1.6-1.5-1.61.6
Bone: cortical tissue density0.70.92.9-1.71.1-1.10.3-0.41.0-1.00.6-0.90.9-1.00.90.90.9-0.9
Bone: elastic displacement1.61.82.81.4-1.21.2-1.01.0-1.51.5-1.21.1-1.11.3-1.3-1.5-1.71.7
Bone: elastic work9.312.115.03.6-3.43.4-3.03.1-3.93.9-3.42.9-2.93.7-3.6-3.8-3.83.8
Bone: endosteal estimation0.30.71.2-0.40.8-0.81.1-1.10.9-0.91.0-0.50.5-0.80.90.60.9-0.9
Bone: endosteal perimeter0.30.61.21.1-0.70.7-0.40.4-1.01.0-0.70.8-0.70.7-1.0-0.9-0.70.7
Bone: final force2.94.77.32.7-2.22.2-1.41.4-2.52.5-1.71.6-1.62.3-2.6-2.7-2.32.3
Bone: final moment3.86.39.23.0-2.52.5-1.71.8-2.92.9-2.01.9-1.92.6-3.0-3.0-2.62.6
Bone: marrow area0.30.71.2-0.40.8-0.81.1-1.10.9-0.91.0-0.50.5-0.81.00.60.9-0.9
Bone: maximum diameter0.61.01.91.4-1.01.0-0.50.5-1.31.3-0.80.6-0.61.0-1.3-1.4-1.01.0
Bone: maximum force2.64.57.72.8-2.22.2-1.31.3-2.32.3-1.51.6-1.62.3-2.4-2.6-2.32.3
Bone: maximum moment3.56.09.53.1-2.52.5-1.61.7-2.72.7-1.92.0-2.02.6-2.8-2.9-2.72.7
Bone: minimum diameter1.83.45.72.3-1.61.6-1.11.1-2.32.3-1.61.5-1.51.9-2.4-2.2-1.91.9
Bone: periosteal estimation0.61.22.51.6-1.01.0-0.40.4-1.31.3-0.70.8-0.81.1-1.4-1.5-1.11.1
Bone: periosteal perimeter3.45.77.72.5-2.32.3-2.02.0-2.72.7-2.32.0-2.02.5-2.8-2.6-2.52.5
Bone: post-yield work0.40.50.9-0.50.6-0.60.8-0.80.8-0.80.9-0.60.7-0.70.90.60.7-0.7
Bone: stiffness0.10.20.60.7-0.50.5-0.10.2-0.50.5-0.10.1-0.10.6-0.7-0.8-0.50.5
Bone: tissue strength0.10.10.30.50.0-0.00.5-0.5-0.20.20.3-0.10.10.1-0.2-0.3-0.00.0
Bone: trabecular number0.00.00.00.00.1-0.10.2-0.20.2-0.20.1-0.10.1-0.10.10.20.1-0.1
Bone: trabecular spacing1.72.24.0-0.71.4-1.42.0-2.01.4-1.41.8-1.31.3-1.51.41.21.5-1.5
Bone: trabecular thickness2.53.14.01.4-1.71.7-2.02.0-1.81.8-2.01.5-1.51.9-1.7-1.6-1.71.7
Bone: trabecular tissue density0.40.51.1-1.00.6-0.60.4-0.40.8-0.80.6-0.80.8-0.70.90.60.8-0.8
Breakpoint value in progressive ratio session1.51.62.61.0-1.41.4-1.41.4-1.41.4-1.41.1-1.11.4-1.6-1.2-0.90.9
Distance traveled before self-admin2.62.83.61.6-1.71.7-1.51.5-1.91.9-1.81.4-1.41.9-1.7-1.7-1.61.6
Distance traveled after self-admin0.10.10.30.60.1-0.10.4-0.4-0.10.10.10.5-0.50.10.2-0.20.1-0.1
Delta time in closed arm before/after self-admin0.60.61.4-0.50.6-0.60.6-0.60.7-0.70.7-1.01.0-0.70.30.71.2-1.2
Delta time in open arm before/after self-admin0.10.10.2-0.10.2-0.20.3-0.30.2-0.20.20.4-0.4-0.20.20.3-0.40.4
Diff in mean of infusions in LGA sessions0.10.10.4-0.30.0-0.0-0.20.20.1-0.1-0.10.0-0.0-0.10.00.60.6-0.6
Extinction: sum of active levers before priming0.20.21.0-1.00.4-0.4-0.10.00.3-0.30.0-0.00.0-0.30.40.6-0.80.8
Active lever presses in extinction session 60.60.51.5-0.0-0.60.6-1.00.9-0.80.8-0.90.2-0.20.8-1.2-0.6-0.60.6
Delta distance traveled before/after self-admin1.81.92.7-1.01.5-1.51.6-1.61.5-1.51.5-0.80.8-1.51.61.31.4-1.4
Delta ambulatory time before/after self-admin2.83.13.7-1.51.9-1.91.7-1.81.9-1.91.7-1.21.2-1.91.91.71.9-1.9
Time in closed arm before self-admin0.50.51.00.3-0.80.8-1.01.0-0.80.8-0.90.5-0.50.8-0.4-0.6-0.70.7
Time in closed arm after self-admin0.60.61.90.1-0.90.9-1.41.4-0.80.8-1.10.0-0.10.8-0.5-0.4-0.10.1
Time in open arm before self-admin0.70.71.0-0.81.0-1.01.0-1.01.0-1.00.9-0.60.7-1.00.20.60.7-0.7
Time in open arm after self-admin0.60.61.2-0.81.0-1.01.1-1.11.0-1.01.0-0.20.3-1.00.60.70.1-0.1
Sum of active levers in priming session hrs 5-62.32.33.31.3-1.51.5-1.41.4-1.51.5-1.41.6-1.61.5-1.6-1.8-1.41.4
Time to tail flick, vehicle, before self-admin0.10.10.50.10.1-0.10.3-0.30.1-0.10.20.7-0.7-0.1-0.0-0.1-0.60.6
Time to tail flick, vehicle, after self-admin1.82.03.0-1.71.5-1.51.1-1.11.4-1.41.2-1.61.6-1.41.21.71.2-1.2
Time to tail flick, test, before self-admin0.30.30.50.6-0.60.6-0.70.7-0.60.6-0.50.1-0.10.6-0.4-0.50.4-0.4
Time to tail flick, test, after self-admin0.20.20.6-0.60.4-0.40.2-0.20.3-0.30.2-0.60.6-0.3-0.30.20.8-0.8
Delta time to tail flick, vehicle, before/after SA1.41.42.1-1.01.2-1.21.0-1.01.1-1.11.1-1.41.4-1.11.01.31.4-1.4
Delta time to tail flick, test, before/after SA0.10.10.4-0.60.1-0.1-0.10.10.1-0.1-0.00.0-0.0-0.1-0.2-0.2-0.40.4
Ambulatory time before self-admin3.53.64.41.9-2.02.0-1.51.6-2.12.1-1.81.8-1.82.1-1.9-2.0-1.91.9
Ambulatory time after self-admin0.10.10.30.5-0.00.00.2-0.2-0.20.2-0.10.5-0.50.2-0.1-0.3-0.30.3
Total heroin consumption1.11.43.00.5-1.21.2-1.31.3-1.11.1-1.20.9-0.91.1-1.7-0.6-1.31.3
Area under the delay curve1.01.01.6-1.20.8-0.80.4-0.41.1-1.10.7-1.31.2-1.10.61.21.2-1.2
Delay disc. indifference point, 0s delay0.10.10.1-0.30.2-0.20.1-0.10.3-0.30.2-0.20.2-0.3-0.00.40.3-0.3
Delay disc. indifference point, 16s delay3.93.94.9-1.82.0-2.01.8-1.82.1-2.11.8-2.01.9-2.11.81.82.2-2.2
Delay disc. indifference point, 2s delay0.10.10.2-0.50.1-0.1-0.10.10.3-0.30.1-0.40.4-0.3-0.40.50.1-0.1
Delay disc. indifference point, 24s delay1.01.03.3-1.80.9-0.90.0-0.11.1-1.10.5-1.21.2-1.10.61.10.8-0.8
Delay disc. indifference point, 4s delay0.20.20.5-0.50.4-0.40.1-0.20.3-0.30.2-0.40.4-0.30.00.50.7-0.7
Delay disc. indifference point, 8s delay0.10.10.3-0.5-0.20.2-0.50.50.2-0.2-0.2-0.60.5-0.2-0.20.30.5-0.5
Delay discount exponential model param0.80.91.81.3-0.80.8-0.20.3-1.01.0-0.61.2-1.11.0-0.6-1.1-1.11.1
Delay discount hyperbolic model param0.80.91.81.3-0.80.8-0.30.3-1.01.0-0.61.2-1.11.0-0.5-1.2-1.11.1
Fecal boli incidents, locomotor time 10.60.71.0-1.01.0-1.00.8-0.80.9-0.90.8-0.70.7-0.90.51.00.3-0.3
Change in fecal boli incidents, locomotor task0.30.30.9-0.4-0.30.3-0.90.9-0.50.5-0.80.7-0.70.5-0.2-0.60.1-0.1
Time >=10cm from walls, locomotor time 10.40.41.20.10.2-0.20.8-0.70.7-0.70.90.1-0.1-0.71.10.40.7-0.7
Bouts of movement, locomotor time 10.50.51.5-1.20.6-0.60.2-0.30.8-0.80.5-0.60.6-0.81.01.10.3-0.3
Total resting periods, locomotor time 10.30.41.5-1.20.5-0.5-0.00.00.6-0.60.3-0.60.6-0.60.80.90.2-0.2
Rest time, locomotor task time 10.20.20.4-0.0-0.30.3-0.60.6-0.40.4-0.50.2-0.20.4-0.6-0.2-0.50.5
Distance moved, locomotor task time 10.20.21.10.4-0.00.00.4-0.4-0.00.00.2-0.20.20.00.3-0.21.1-1.1
Vertical activity count, locomotor time 10.30.30.80.30.3-0.30.9-0.80.4-0.40.6-0.20.2-0.40.40.40.7-0.7
Time >=10cm from walls, locomotor time 20.10.10.2-0.0-0.20.20.0-0.00.3-0.30.30.5-0.4-0.30.2-0.1-0.40.4
Bouts of movement, locomotor time 21.31.33.0-1.20.6-0.60.4-0.41.2-1.21.0-1.41.5-1.21.21.71.4-1.4
Total resting periods, locomotor time 21.61.73.3-1.20.8-0.80.7-0.71.3-1.31.2-1.51.6-1.31.31.81.6-1.6
Rest time, locomotor task time 20.10.10.4-0.10.2-0.20.1-0.10.2-0.20.0-0.60.6-0.20.10.70.5-0.5
Distance moved, locomotor task time 20.10.10.5-0.1-0.00.00.1-0.10.1-0.10.20.1-0.1-0.10.2-0.10.7-0.7
Vertical activity count, locomotor time 20.50.61.0-0.40.7-0.71.0-1.00.9-0.91.0-0.30.4-0.90.80.70.6-0.6
Weight adjusted by age2.42.74.91.7-1.41.4-0.91.0-1.61.6-1.22.0-2.01.7-1.8-1.5-2.22.2
Seeking ratio, delayed vs. immediate footshock0.50.61.31.2-0.80.8-0.30.3-0.70.7-0.41.0-0.90.7-0.8-0.8-0.70.7
Locomotion in novel chamber0.50.61.2-0.70.5-0.50.6-0.61.0-1.00.8-0.80.8-1.11.00.90.6-0.6
Locomotion in novel chamber post-restriction1.31.63.41.8-1.41.4-0.90.9-1.41.4-1.01.3-1.31.4-0.8-1.3-1.01.0
Progressive ratio0.20.20.5-0.70.5-0.50.2-0.20.5-0.50.3-0.30.3-0.50.20.60.4-0.4
Food seeking constrained by brief footshock0.20.20.60.1-0.50.5-0.80.7-0.40.4-0.60.3-0.30.4-0.5-0.2-0.30.3
Seeking ratio, punishment vs. effort0.00.00.20.4-0.30.3-0.10.1-0.20.2-0.10.0-0.10.20.0-0.3-0.10.1
Run reversals in cocaine runway, females1.11.12.7-1.01.0-1.01.0-1.01.3-1.31.2-0.50.5-1.41.71.00.6-0.6
Run reversals in cocaine runway, males3.33.23.91.7-1.81.8-1.71.7-1.81.8-1.81.8-1.81.8-2.0-1.7-1.71.7
Latency to leave start box in cocaine runway0.70.71.1-0.70.9-0.90.8-0.80.7-0.70.8-1.01.0-0.61.00.91.0-1.0
Latency to leave start box in cocaine runway, F1.71.92.6-1.21.6-1.61.6-1.61.4-1.41.5-1.11.1-1.31.31.41.0-1.0
Latency to leave start box in cocaine runway, M0.20.20.40.5-0.60.6-0.60.6-0.60.6-0.5-0.30.20.60.1-0.30.5-0.5
Cd content in liver1.21.32.2-1.51.2-1.20.8-0.81.3-1.31.1-1.21.2-1.11.31.40.8-0.8
Co content in liver0.20.20.4-0.50.6-0.60.4-0.40.2-0.20.3-0.50.5-0.50.20.40.4-0.4
Cu content in liver1.31.62.71.0-1.31.3-1.61.6-1.41.4-1.60.8-0.81.3-1.6-0.8-1.21.2
Fe content in liver0.80.91.5-1.21.0-1.00.8-0.81.0-1.00.8-0.70.7-1.11.01.20.8-0.8
K content in liver0.10.10.70.80.0-0.00.5-0.5-0.10.10.2-0.10.10.0-0.4-0.10.4-0.4
Mg content in liver1.71.72.6-0.51.2-1.21.6-1.61.4-1.41.5-1.11.1-1.21.11.11.6-1.6
Mn content in liver0.10.10.30.5-0.50.5-0.40.4-0.40.4-0.40.2-0.20.4-0.4-0.4-0.30.3
Na content in liver0.10.10.30.00.0-0.00.1-0.1-0.00.0-0.1-0.50.5-0.1-0.10.20.5-0.5
Rb content in liver0.10.10.30.5-0.10.10.4-0.40.4-0.40.50.2-0.1-0.30.10.1-0.20.2
Se content in liver0.00.00.30.5-0.20.20.1-0.0-0.10.1-0.10.3-0.30.2-0.2-0.20.0-0.0
Sr content in liver1.81.72.60.6-1.31.3-1.61.6-1.21.2-1.51.3-1.31.1-1.2-1.0-1.41.4
Zn content in liver0.00.00.1-0.10.2-0.2-0.00.00.1-0.1-0.1-0.30.30.1-0.20.20.2-0.2