Hub : Genes

ENSRNOG00000069263

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	intron excision ratio	chr12:6037500:6055767	0.21	0.1	2.7e-04	0.05	0.06	0.05	0.03	1.1e-05	5.5e-06	1.5e-05	9.4e-04
2	Brain	intron excision ratio	chr12:6037500:6064708	0.22	0.1	1.9e-04	0.04	0.06	0.05	0.03	2.3e-04	5.7e-06	1.3e-05	5.3e-04
3	OFC	gene expression	ENSRNOG00000069263	0.24	0.14	1.1e-03	0.12	0.07	0.04	0.1	1.0e-03	7.9e-03	4.7e-02	2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
BMI with tail	1.0	3.2	9.1	0.5	-0.3	-3.0
BMI without tail	0.2	0.3	0.5	-0.6	0.7	-0.2
Body weight	3.6	15.2	44.0	1.0	-0.7	-6.6
Epididymis fat weight	1.5	3.6	10.4	0.4	-0.3	-3.2
Glucose	0.9	1.4	1.6	1.1	-1.1	-1.3
Heart weight	0.0	0.0	0.1	0.2	-0.2	0.3
Left kidney weight	1.9	5.6	15.6	0.8	-0.7	-3.9
Right kidney weight	4.0	11.5	28.1	1.9	-1.7	-5.3
Tail length	0.1	0.4	0.5	-0.6	0.7	-0.7
Length with tail	1.6	6.0	17.9	0.3	-0.2	-4.2
Length without tail	4.3	9.4	26.4	1.0	-0.9	-5.1
Liver weight, left	1.3	2.0	5.8	-0.3	0.4	-2.4
Liver weight, right	1.5	2.5	6.7	-0.6	0.7	-2.6
Parametrial fat weight	0.9	1.7	1.8	1.4	-1.3	-1.2
Retroperitoneal fat weight	0.8	2.6	7.2	-0.5	0.6	-2.7
Intraocular pressure	0.6	0.8	1.0	-1.0	1.0	-0.6
Extensor digitorum longus weight	0.6	2.6	6.8	-0.6	0.8	-2.6
Soleus weight	0.7	2.0	3.0	-1.1	1.3	-1.7
Tibialis anterior weight	0.7	2.3	6.7	-0.1	0.2	-2.6
Tibia length	0.5	1.4	4.1	-0.2	0.3	-2.0
Number of licking bursts	1.0	1.1	1.2	1.1	-1.1	-1.0
Food consumed during 24 hour testing period	0.6	0.7	2.2	-0.2	0.2	1.5
Times rat made contact with spout	0.1	0.1	0.2	-0.1	0.0	0.5
Mean time between licks in bursts	0.1	0.1	0.2	-0.4	0.4	0.2
Mean num. licks in bursts	1.0	1.2	1.7	-1.0	1.0	1.3
Std. dev. time between licks in bursts	0.1	0.1	0.2	0.4	-0.4	0.0
Water consumed over 24 hours	0.2	0.2	0.3	0.5	-0.5	-0.1
Indifference point 0 sec	0.2	0.4	0.8	0.4	-0.4	-0.9
Indifference point AUC	0.1	0.1	0.2	0.2	-0.2	-0.4
Indifference point function ln k	0.2	0.2	0.3	0.5	-0.5	-0.3
Indifference point function log k	0.2	0.2	0.3	0.5	-0.5	-0.3
Delay discounting total patch changes 0 sec	0.1	0.1	0.4	0.1	-0.1	-0.6
Delay discounting total patch changes 12 sec	0.3	0.4	0.7	0.5	-0.5	-0.9
Delay discounting total patch changes 18 sec	0.0	0.0	0.1	0.2	-0.2	-0.2
Delay discounting total patch changes 24 sec	0.0	0.0	0.0	0.1	-0.1	0.2
Delay discounting total patch changes 6 sec	0.1	0.2	0.2	-0.5	0.5	0.2
Delay discounting time to switch 0 sec	0.4	0.7	0.8	-0.8	0.8	0.9
Delay discounting water rate 0 sec	0.3	0.5	1.3	0.4	-0.4	-1.1
Delay discounting water rate 12 sec	0.2	0.3	0.9	0.0	0.0	-0.9
Delay discounting water rate 18 sec	1.0	1.4	1.5	-1.2	1.2	1.1
Delay discounting water rate 24 sec	0.1	0.1	0.1	0.2	-0.2	-0.3
Delay discounting water rate 6 sec	0.5	0.7	1.0	-0.7	0.7	-1.0
Locomotor activity	0.4	0.6	0.9	-0.6	0.7	-1.0
Locomotor testing distance	0.2	0.3	0.9	0.1	-0.1	-0.9
Locomotor testing rearing	0.3	0.4	0.7	-0.8	0.8	0.0
Light reinforcement 1	0.1	0.2	0.6	0.1	-0.1	0.8
Light reinforcement 2	0.9	1.2	1.5	1.2	-1.2	-0.8
Reaction time number correct	1.1	1.6	1.9	1.4	-1.4	-1.0
Reaction time mean minus median	8.4	11.0	12.7	-3.6	3.5	2.8
Reaction time mean minus median AUC	7.9	10.1	10.7	-3.3	3.2	3.1
Reaction time num false alarms	0.5	0.7	1.1	1.0	-1.1	0.0
Reaction time num false alarms AUC	0.2	0.3	0.4	0.7	-0.6	-0.2
Reaction time trials correct on left	1.1	1.6	1.9	1.4	-1.4	-1.0
Reaction time trials on left	1.0	1.4	1.6	1.3	-1.3	-1.0
Reaction time mean	3.9	5.4	6.6	-2.2	2.2	2.6
Reaction time mean AUC	4.3	5.8	5.9	-2.4	2.4	2.4
Median of all reaction times	1.8	2.5	3.9	-1.3	1.3	2.0
Reaction time omissions	1.7	2.4	2.8	-1.7	1.6	1.3
Reaction time false alarm rate	0.0	0.0	0.0	0.0	-0.0	0.0
Reaction time premature initiation rate	3.9	5.3	13.2	-1.2	1.1	3.6
Reaction time premature initiations	2.1	3.0	8.1	-0.7	0.6	2.8
Std. dev. reaction times	7.2	9.9	11.4	-3.4	3.3	2.7
Reaction time trials completed	1.0	1.4	1.6	1.3	-1.3	-1.0
Reaction time trials AUC	1.1	1.5	1.8	1.3	-1.3	-1.0
Social response proportion	1.4	1.5	2.3	-1.5	1.5	-0.2
Social responses	4.3	5.6	7.2	-2.7	2.7	1.6
Social time	1.3	1.7	2.5	-1.5	1.6	0.3
Conditioned locomotion	0.2	0.2	0.4	0.3	-0.3	0.6
Cocaine response after cond. corrected	0.2	0.2	0.3	0.5	-0.5	0.2
Cocaine response after cond. not corrected	0.2	0.2	0.3	0.6	-0.6	0.1
Cocaine response before conditioning	0.3	0.3	0.5	-0.7	0.7	0.1
Saline control response	0.6	0.8	0.9	-0.9	0.9	0.9
Condit. Reinf. active minus inactive responses	0.6	0.7	1.4	-0.7	0.6	1.2
Condit. Reinf. active-inactive response ratio	0.9	0.9	1.8	-0.7	0.7	1.3
Condit. Reinf. active responses	0.2	0.3	0.6	-0.3	0.3	0.8
Condit. Reinf. inactive responses	0.0	0.0	0.0	0.2	-0.2	0.1
Condit. Reinf. lever presses	0.1	0.1	0.2	-0.4	0.4	-0.1
Condit. Reinf. lever reinforcers received	0.2	0.2	0.5	-0.3	0.3	0.7
Pavlov. Cond. lever latency	0.5	0.7	0.8	0.9	-0.9	-0.7
Pavlov. Cond. magazine entry latency	0.2	0.2	0.3	-0.5	0.5	-0.0
Pavlov. Cond. change in total contacts	0.3	0.5	0.7	-0.8	0.9	0.1
Pavlov. Cond. index score	0.3	0.4	0.5	-0.7	0.7	0.4
Pavlov. Cond. latency score	0.3	0.3	0.4	-0.6	0.6	0.4
Pavlov. Cond. lever contacts	0.4	0.6	0.6	-0.7	0.7	0.8
Pavlov. Cond. magazine entry number	0.1	0.2	0.2	0.5	-0.5	-0.2
Pavlov. Cond. intertrial magazine entries	0.3	0.4	0.9	0.4	-0.4	0.9
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.5	-0.7	0.7	0.3
Pavlov. Cond. response bias	0.7	1.0	1.1	-1.0	0.9	1.1
Conditioned reinforcement - actives	1.9	1.9	2.7	1.2	-1.2	-1.6
Conditioned reinforcement - inactives	1.5	1.7	2.0	1.4	-1.4	-1.1
Conditioned locomotion	0.0	0.0	0.0	-0.0	0.0	0.1
Intermittent access intake day 1-15 change	0.1	0.1	0.2	-0.4	0.4	0.1
Intermittent access intake escalation	0.2	0.1	0.2	-0.5	0.5	-0.0
Intermittent access intake escalation 2	0.2	0.2	0.3	-0.5	0.5	0.2
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.1	-0.2	0.2	-0.3
Intermitt. access day 15 inactive lever presses	0.5	0.5	0.9	-0.9	0.9	0.0
Intermitt. access escalation Index	0.2	0.1	0.2	-0.4	0.4	0.2
Intermittent access day 1 total infusions	0.2	0.2	0.6	0.2	-0.1	0.8
Intermittent access day 15 total infusions	0.2	0.2	0.6	-0.2	0.2	0.8
Intermittent access terminal intake (last 3 days)	0.2	0.3	0.8	-0.1	0.2	0.9
Intermittent access total infusions	0.4	0.5	1.4	0.1	-0.1	1.2
Intermittent access day 1 locomotion	0.5	0.5	1.4	-0.0	-0.0	1.2
Intermittent access day 15 total locomotion	1.2	1.3	3.1	-0.7	0.6	1.8
Intermittent access total locomotion	1.1	1.2	3.7	0.1	-0.1	1.9
Intermittent access standard deviation	0.4	0.4	0.7	-0.8	0.8	-0.3
Cocaine induced anxiety	0.6	0.6	0.9	1.0	-1.0	0.2
Post-drug Anxiety	0.9	1.0	2.4	0.5	-0.5	1.5
Baseline Anxiety	0.5	0.6	0.7	-0.8	0.9	0.5
Lifetime Intake	0.3	0.4	0.5	0.6	-0.5	0.7
Incentive Sensitization - Responses	1.0	1.0	1.5	1.2	-1.2	0.0
Incentive Sensitization - Breakpoint	1.0	1.0	1.5	1.2	-1.2	0.1
Progressive ratio test 1 active lever presses	0.2	0.2	0.3	0.5	-0.5	-0.4
Progressive ratio test 1 breakpoint	0.2	0.2	0.3	0.5	-0.5	-0.1
Progressive ratio test 1 inactive lever presses	0.2	0.2	0.7	0.1	0.0	-0.9
Progressive ratio test 2 active lever presses	0.9	0.9	1.4	1.2	-1.2	-0.1
Progressive ratio test 2 breakpoint	0.8	0.8	1.3	1.1	-1.1	0.1
Progressive ratio test 2 inactive lever presses	0.2	0.3	0.3	0.5	-0.5	-0.5
Total sessions with >9 infusions	0.3	0.3	0.3	-0.5	0.6	-0.6
Short access day 1 total inactive lever presses	0.4	0.4	1.1	-0.2	0.3	-1.1
Short access day 10 total inactive lever presses	0.9	1.0	1.2	-1.1	1.1	0.8
Short access day 1 total infusions	0.7	0.7	0.8	0.8	-0.8	-0.9
Short access day 10 total infusions	0.2	0.2	0.4	0.6	-0.6	0.0
Short access total infusions	0.5	0.6	0.9	0.9	-0.9	-0.1
Short access day 1 locomotion	0.2	0.3	0.4	0.6	-0.6	-0.1
Short access day 10 total locomotion	0.3	0.3	0.8	0.3	-0.2	-0.9
Short access total locomotion	0.2	0.2	0.4	-0.4	0.4	0.6
Compulsive drug intake	0.6	0.6	0.7	-0.8	0.8	0.8
One hour access (0.3 mA shock)	0.3	0.3	0.8	0.3	-0.3	0.9
One hour access (shock baseline)	0.2	0.2	0.2	0.5	-0.5	0.4
Number of responses in last shaping day	0.6	0.6	0.9	-0.9	0.9	-0.0
Context. condit. distance diff. score	2.3	2.8	3.8	-1.9	2.0	-1.0
Locomotion velocity, session 1	0.0	0.0	0.0	-0.1	0.1	0.1
Locomotion distance, session 1	0.9	1.1	1.7	1.3	-1.3	0.1
Locomotion velocity, session 2	1.7	2.0	2.7	1.6	-1.6	-1.0
Locomotion distance, session 2	0.6	0.9	1.4	1.2	-1.2	0.1
Locomotion velocity, session 3	0.1	0.1	0.4	-0.2	0.2	-0.6
Locomotion distance, session 3	0.2	0.2	0.5	0.1	-0.1	0.7
Stereotopy head waving bouts, day 3	0.7	0.9	1.4	-0.7	0.8	-1.2
Stereotopy head waving duration, day 3	1.3	1.6	2.4	-1.5	1.5	-0.3
Locomotion velocity, session 7	4.4	4.8	6.6	-2.6	2.6	1.1
Locomotion distance, session 7	4.3	5.4	6.7	-2.6	2.6	1.7
Stereotopy head waving bouts, day 7	1.3	1.5	2.0	-1.1	1.1	1.4
Stereotopy head waving duration, day 7	0.0	0.0	0.1	-0.0	-0.0	0.4
Locomotion velocity, session 8	0.0	0.1	0.1	-0.1	0.0	0.4
Locomotion distance, session 8	0.2	0.4	0.7	-0.4	0.5	-0.8
Degree of sensitization distance	2.2	2.2	3.0	-1.7	1.7	0.8
Degree of sensitization stereotypy	0.1	0.1	0.4	-0.1	0.1	0.6
Condit. Reinf. active minus inactive responses	0.4	0.5	1.3	0.2	-0.2	-1.1
Condit. Reinf. active-inactive response ratio	0.1	0.2	0.3	-0.3	0.3	-0.5
Condit. Reinf. active responses	0.4	0.4	0.7	0.6	-0.6	-0.8
Condit. Reinf. inactive responses	0.1	0.1	0.1	0.3	-0.3	0.2
Incentive salience index mean	0.1	0.1	0.2	-0.1	0.1	-0.5
Condit. Reinf. lever presses	0.0	0.0	0.0	-0.1	0.1	-0.0
Time in familiar zone, hab. session 1	0.8	0.8	1.0	1.0	-1.0	-0.6
Time in novel zone, hab. session 1	0.5	0.5	0.7	-0.8	0.9	-0.3
Total zone transitions, hab. session 1	1.0	1.4	2.0	-1.0	1.0	1.4
Total locomotion distance, hab. session 1	1.9	2.7	3.2	-1.8	1.8	1.3
Locomotion velocity, hab. session 1	2.0	2.9	3.2	-1.7	1.7	1.8
Time in familiar zone, hab. session 2	1.5	1.5	2.2	-1.5	1.5	-0.5
Time in novel zone, hab. session 2	0.7	0.8	1.1	1.0	-1.0	0.4
Total zone transitions, hab. session 2	1.3	1.7	2.6	1.6	-1.6	-0.0
Total locomotion distance, hab. session 2	0.5	0.6	0.7	0.8	-0.8	0.7
Locomotion velocity, hab. session 2	0.7	1.0	1.2	1.1	-1.1	0.7
Novel to familiar place preference ratio	0.3	0.3	0.5	0.7	-0.7	-0.0
Novelty place preference	0.3	0.3	0.5	0.7	-0.7	-0.1
Time in novel zone, NPP test	0.3	0.3	0.5	0.7	-0.7	-0.2
Total zone transitions, NPP test	0.1	0.1	0.1	0.4	-0.4	-0.3
Total locomotion distance, NPP test	0.4	0.5	0.7	-0.7	0.7	0.8
Locomotion velocity, NPP test	0.5	0.8	0.9	-0.8	0.8	1.0
Pavlov. Cond. lever latency	2.9	3.7	5.0	1.8	-1.8	-2.2
Pavlov. Cond. magazine entry latency	1.3	1.7	2.6	-1.1	1.1	1.6
Pavlov. Cond. change in total contacts	2.5	2.6	3.3	-1.8	1.8	1.1
Pavlov. Cond. index score	2.3	3.0	3.3	-1.7	1.7	1.8
Pavlov. Cond. latency score	2.0	2.6	3.9	-1.4	1.4	2.0
Pavlov. Cond. lever contacts	3.4	4.0	5.4	-1.8	1.8	2.3
Pavlov. Cond. magazine entry number	3.0	3.8	4.2	2.1	-2.1	-1.7
Pavlov. Cond. intertrial magazine entries	0.6	0.7	1.1	1.0	-1.0	-0.1
Pavlov. Cond. lever-magazine prob. diff.	1.9	2.4	2.4	-1.5	1.5	1.6
Pavlov. Cond. response bias	2.6	3.2	3.4	-1.8	1.8	1.7
Bone: apparent density	5.1	8.5	19.0	1.9	-1.7	-4.4
Bone surface	3.1	5.5	15.3	0.8	-0.7	-3.9
Bone volume	3.8	6.5	17.4	1.1	-0.9	-4.2
Bone: connectivity density	2.4	3.8	10.6	0.7	-0.5	-3.3
Bone: cortical apparent density	0.9	1.2	1.7	1.3	-1.3	-0.4
Bone: cortical area	1.7	2.5	7.5	-0.2	0.3	-2.7
Bone: cortical porosity	0.0	0.0	0.1	-0.0	0.0	0.3
Bone: cortical porosity	0.3	0.4	0.5	-0.5	0.6	0.7
Bone: cortical thickness	1.2	1.9	5.7	0.2	-0.2	-2.4
Bone: cortical thickness	0.7	0.8	2.0	-0.5	0.5	1.4
Bone: cortical tissue density	0.9	1.2	1.7	1.3	-1.3	-0.3
Bone: elastic displacement	0.7	0.8	1.3	1.1	-1.1	0.1
Bone: elastic work	0.7	0.9	0.9	0.9	-0.9	-0.9
Bone: endosteal estimation	0.2	0.3	0.9	0.3	-0.3	-0.9
Bone: endosteal perimeter	0.5	1.0	3.1	-0.1	0.1	-1.8
Bone: final force	0.1	0.2	0.6	0.0	0.0	-0.8
Bone: final moment	0.2	0.2	0.7	0.1	-0.1	-0.9
Bone: marrow area	0.1	0.3	0.7	0.3	-0.3	-0.9
Bone: maximum diameter	1.4	2.5	7.4	0.0	0.1	-2.7
Bone: maximum force	0.3	0.5	1.3	-0.4	0.4	-1.1
Bone: maximum moment	0.3	0.6	1.6	-0.2	0.3	-1.3
Bone: minimum diameter	0.3	0.6	0.8	-0.9	0.9	-0.6
Bone: periosteal estimation	0.7	1.5	4.5	0.0	0.1	-2.1
Bone: periosteal perimeter	1.1	1.9	4.6	-0.7	0.8	-2.2
Bone: post-yield work	0.1	0.2	0.5	-0.1	0.1	-0.7
Bone: stiffness	0.1	0.1	0.2	-0.4	0.4	-0.1
Bone: tissue strength	1.3	1.3	1.9	1.0	-1.0	-1.4
Bone: trabecular number	2.3	3.6	10.1	0.6	-0.5	-3.2
Bone: trabecular spacing	0.4	0.6	1.6	-0.2	0.1	1.3
Bone: trabecular thickness	4.3	5.2	10.4	1.7	-1.6	-3.2
Bone: trabecular tissue density	0.0	0.1	0.1	-0.3	0.3	0.1
Breakpoint value in progressive ratio session	0.8	0.9	1.4	-1.2	1.2	0.1
Distance traveled before self-admin	0.1	0.1	0.1	0.3	-0.3	-0.3
Distance traveled after self-admin	0.0	0.0	0.0	-0.1	0.1	0.0
Delta time in closed arm before/after self-admin	0.2	0.2	0.5	-0.1	0.1	-0.7
Delta time in open arm before/after self-admin	1.5	1.4	4.2	-0.2	0.1	2.1
Diff in mean of infusions in LGA sessions	2.4	2.7	3.7	-1.9	1.9	0.9
Extinction: sum of active levers before priming	1.0	1.0	1.0	1.0	-1.0	-1.0
Active lever presses in extinction session 6	1.1	1.1	3.2	-0.0	0.1	-1.8
Delta distance traveled before/after self-admin	0.4	0.5	0.7	-0.6	0.6	0.8
Delta ambulatory time before/after self-admin	0.5	0.5	0.6	-0.8	0.8	0.6
Time in closed arm before self-admin	0.4	0.4	0.6	0.6	-0.5	-0.8
Time in closed arm after self-admin	0.5	0.5	1.4	0.3	-0.3	-1.2
Time in open arm before self-admin	0.3	0.3	1.0	-0.0	0.1	-1.0
Time in open arm after self-admin	0.3	0.3	0.8	-0.3	0.2	0.9
Sum of active levers in priming session hrs 5-6	0.2	0.1	0.4	-0.2	0.2	-0.6
Time to tail flick, vehicle, before self-admin	0.8	0.8	0.9	-0.9	0.9	0.8
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.1	-0.3	0.3	0.3
Time to tail flick, test, before self-admin	0.6	0.6	1.6	0.4	-0.3	-1.3
Time to tail flick, test, after self-admin	0.0	0.0	0.1	0.1	-0.1	0.3
Delta time to tail flick, vehicle, before/after SA	0.4	0.4	0.6	0.8	-0.8	-0.2
Delta time to tail flick, test, before/after SA	0.6	0.5	1.5	-0.2	0.2	1.2
Ambulatory time before self-admin	0.1	0.1	0.1	0.3	-0.3	0.0
Ambulatory time after self-admin	0.1	0.1	0.1	-0.4	0.4	0.0
Total heroin consumption	0.6	0.7	0.8	-0.9	0.9	0.7
Area under the delay curve	1.7	1.8	2.1	-1.5	1.4	1.2
Delay disc. indifference point, 0s delay	0.3	0.3	0.5	-0.7	0.7	-0.1
Delay disc. indifference point, 16s delay	0.7	0.7	1.0	-1.0	1.0	0.3
Delay disc. indifference point, 2s delay	2.0	2.2	3.0	-1.4	1.4	1.7
Delay disc. indifference point, 24s delay	1.1	1.1	1.5	-1.2	1.2	0.4
Delay disc. indifference point, 4s delay	0.4	0.4	0.5	-0.7	0.7	0.4
Delay disc. indifference point, 8s delay	0.9	0.9	1.9	-0.7	0.7	1.4
Delay discount exponential model param	2.0	2.1	2.4	1.6	-1.5	-1.3
Delay discount hyperbolic model param	1.9	2.0	2.2	1.5	-1.5	-1.3
Fecal boli incidents, locomotor time 1	0.7	0.7	2.0	0.3	-0.3	-1.4
Change in fecal boli incidents, locomotor task	0.6	0.5	1.6	-0.2	0.2	1.2
Time >=10cm from walls, locomotor time 1	1.4	1.4	2.1	1.4	-1.4	-0.0
Bouts of movement, locomotor time 1	0.1	0.1	0.2	-0.2	0.2	-0.4
Total resting periods, locomotor time 1	0.0	0.0	0.1	0.1	-0.1	-0.3
Rest time, locomotor task time 1	0.9	1.0	1.2	1.1	-1.1	0.7
Distance moved, locomotor task time 1	0.1	0.2	0.4	-0.1	0.1	-0.7
Vertical activity count, locomotor time 1	0.8	0.8	2.1	0.5	-0.4	-1.4
Time >=10cm from walls, locomotor time 2	0.0	0.0	0.1	-0.1	0.2	-0.2
Bouts of movement, locomotor time 2	0.9	1.0	2.9	0.1	-0.0	-1.7
Total resting periods, locomotor time 2	1.2	1.3	3.4	0.5	-0.4	-1.8
Rest time, locomotor task time 2	0.4	0.4	0.6	0.5	-0.6	0.8
Distance moved, locomotor task time 2	0.2	0.2	0.7	-0.0	0.1	-0.8
Vertical activity count, locomotor time 2	2.1	2.3	5.5	0.9	-0.8	-2.3
Weight adjusted by age	0.4	0.5	0.8	0.5	-0.5	-0.9
Seeking ratio, delayed vs. immediate footshock	0.9	1.0	2.8	0.2	-0.3	1.7
Locomotion in novel chamber	0.9	1.1	1.6	0.9	-1.0	1.2
Locomotion in novel chamber post-restriction	0.3	0.3	0.5	0.7	-0.7	-0.2
Progressive ratio	0.1	0.1	0.2	0.2	-0.2	0.4
Food seeking constrained by brief footshock	1.2	1.5	1.9	1.4	-1.4	-0.8
Seeking ratio, punishment vs. effort	0.7	0.9	0.9	1.0	-1.0	-0.9
Run reversals in cocaine runway, females	0.0	0.0	0.1	-0.0	-0.0	0.3
Run reversals in cocaine runway, males	1.4	1.3	3.3	0.6	-0.6	-1.8
Latency to leave start box in cocaine runway	1.1	1.2	1.7	-1.3	1.3	0.4
Latency to leave start box in cocaine runway, F	0.8	0.9	1.1	-1.0	1.0	-0.7
Latency to leave start box in cocaine runway, M	1.0	0.9	2.6	-0.3	0.3	1.6
Cd content in liver	0.2	0.2	0.5	0.4	-0.4	0.7
Co content in liver	0.5	0.6	1.4	0.4	-0.4	1.2
Cu content in liver	1.3	1.5	4.0	-0.5	0.6	-2.0
Fe content in liver	3.7	4.4	13.1	0.4	-0.3	-3.6
K content in liver	0.3	0.3	0.7	0.2	-0.2	0.9
Mg content in liver	1.0	1.1	2.3	-0.7	0.7	1.5
Mn content in liver	0.0	0.0	0.0	-0.1	0.1	0.1
Na content in liver	0.5	0.5	0.6	0.7	-0.8	0.5
Rb content in liver	3.3	4.2	5.1	-2.3	2.2	1.6
Se content in liver	0.9	1.1	1.4	1.0	-1.0	-1.2
Sr content in liver	0.9	0.8	1.4	0.7	-0.6	-1.2
Zn content in liver	2.5	2.7	4.3	1.4	-1.4	-2.1