Hub : Genes

ENSRNOG00000068595

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000068595	0.24	0.1	2.0e-13	0.12	0.1	0.11	0.11	6.2e-13	1.6e-11	2.8e-12	2.8e-12
2	Adipose	isoform ratio	ENSRNOT00000104915	0.05	0.03	2.3e-05	0.01	0.03	0.02	0.02	1.7e-02	1.3e-04	1.1e-03	1.6e-03
3	Adipose	isoform ratio	ENSRNOT00000117880	0.03	0.02	1.6e-03	0	0.01	0.01	0.01	7.5e-02	2.1e-02	4.4e-02	5.0e-02
4	BLA	isoform ratio	ENSRNOT00000104915	0.06	0.04	6.5e-03	0	0.01	-0	0	1.8e-01	1.5e-01	4.7e-01	2.1e-01
5	Brain	gene expression	ENSRNOG00000068595	0.04	0.03	3.7e-04	0	0.01	0.01	0	3.1e-01	1.8e-02	6.8e-02	1.4e-01
6	Liver	gene expression	ENSRNOG00000068595	0.03	0.02	9.4e-03	0.01	-0	-0	0.01	6.8e-02	9.1e-01	9.7e-01	9.9e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
BMI with tail	1.9	6.2	10.6	-1.7	2.3	-2.0	2.7	-2.7	-3.3
BMI without tail	2.6	5.5	8.8	-1.7	2.0	-1.8	2.8	-3.0	-2.5
Body weight	0.2	0.9	2.4	1.5	-1.1	0.9	0.2	-0.7	0.5
Epididymis fat weight	1.9	4.4	9.2	-1.5	0.4	0.2	2.7	-3.0	-2.7
Glucose	0.2	0.3	0.6	0.8	0.3	-0.6	-0.4	0.5	0.7
Heart weight	0.1	0.2	0.4	0.2	-0.5	0.6	0.3	-0.6	0.2
Left kidney weight	0.6	1.8	2.9	1.7	-1.5	1.3	-1.2	1.0	1.1
Right kidney weight	0.2	0.5	1.2	0.9	-1.1	1.0	-0.3	0.1	0.3
Tail length	0.8	2.3	4.7	1.3	-2.2	2.1	-0.4	-0.0	1.6
Length with tail	4.0	14.5	21.0	4.2	-4.6	4.0	-2.9	2.3	4.3
Length without tail	5.5	12.1	15.3	3.9	-3.8	3.2	-3.3	2.9	3.6
Liver weight, left	0.0	0.1	0.1	0.4	0.2	-0.3	-0.2	0.3	-0.1
Liver weight, right	0.5	0.8	1.0	-0.9	0.9	-0.8	1.0	-1.0	-0.9
Parametrial fat weight	0.0	0.1	0.3	-0.2	-0.1	0.2	0.4	-0.6	-0.1
Retroperitoneal fat weight	0.4	1.4	3.2	-0.0	0.6	-0.5	1.4	-1.6	-1.8
Intraocular pressure	0.3	0.5	1.1	-0.8	0.4	-0.2	1.0	-1.0	-0.4
Extensor digitorum longus weight	0.7	3.0	6.1	1.7	-2.1	1.8	-1.0	0.6	2.5
Soleus weight	0.3	0.9	4.8	-0.3	0.1	-0.4	-0.4	0.3	2.2
Tibialis anterior weight	2.1	7.1	10.6	3.0	-3.0	2.6	-2.1	1.6	3.3
Tibia length	0.5	1.5	2.7	1.6	-0.6	0.1	-1.3	1.3	1.5
Number of licking bursts	0.1	0.1	0.4	-0.6	-0.1	0.2	0.1	0.1	-0.2
Food consumed during 24 hour testing period	0.2	0.2	0.5	-0.7	-0.1	0.2	0.5	-0.5	0.3
Times rat made contact with spout	4.6	5.2	8.2	-2.7	1.0	-0.3	2.9	-2.9	-2.6
Mean time between licks in bursts	0.2	0.3	0.7	-0.4	0.8	-0.9	0.4	-0.4	-0.0
Mean num. licks in bursts	1.2	1.5	3.6	-0.9	0.4	-0.0	1.7	-1.9	-1.2
Std. dev. time between licks in bursts	0.1	0.1	0.2	0.1	-0.2	0.2	-0.3	0.4	0.3
Water consumed over 24 hours	0.2	0.3	0.6	-0.0	-0.3	0.3	0.7	-0.8	-0.6
Indifference point 0 sec	3.4	5.5	6.5	2.1	-2.5	2.2	-2.4	2.3	2.4
Indifference point AUC	2.5	2.9	5.4	1.6	-0.2	-0.4	-2.1	2.3	2.2
Indifference point function ln k	0.8	1.2	2.4	-0.5	-0.6	1.0	1.2	-1.6	-1.2
Indifference point function log k	0.8	1.2	2.4	-0.5	-0.6	1.0	1.2	-1.6	-1.2
Delay discounting total patch changes 0 sec	3.1	5.1	6.0	2.1	-2.4	2.1	-2.3	2.2	2.4
Delay discounting total patch changes 12 sec	2.5	3.3	5.3	1.8	-1.1	0.6	-2.2	2.3	2.2
Delay discounting total patch changes 18 sec	1.3	1.7	2.4	1.0	-1.6	1.3	-1.2	1.3	1.4
Delay discounting total patch changes 24 sec	2.5	3.2	5.1	1.6	-1.4	1.0	-2.1	2.3	2.0
Delay discounting total patch changes 6 sec	4.2	6.4	9.7	2.6	-1.6	0.9	-3.0	3.1	3.0
Delay discounting time to switch 0 sec	7.3	11.2	15.8	-3.2	2.9	-2.2	3.8	-3.7	-4.0
Delay discounting water rate 0 sec	2.8	4.5	5.9	2.1	-2.4	2.1	-2.0	1.6	2.4
Delay discounting water rate 12 sec	2.5	3.7	5.1	2.3	-2.0	1.6	-1.9	1.6	2.2
Delay discounting water rate 18 sec	0.3	0.4	0.8	0.8	-0.9	0.9	-0.3	0.1	0.4
Delay discounting water rate 24 sec	0.2	0.2	0.4	0.6	-0.6	0.6	0.2	-0.5	-0.2
Delay discounting water rate 6 sec	0.6	0.9	1.6	1.3	-0.7	0.4	-1.0	0.9	1.1
Locomotor activity	11.4	18.1	28.2	5.3	-4.2	3.2	-4.3	3.9	4.3
Locomotor testing distance	10.0	16.5	26.0	5.1	-4.0	3.2	-4.1	3.7	4.0
Locomotor testing rearing	5.8	9.1	14.4	3.8	-2.6	1.7	-3.1	3.0	3.4
Light reinforcement 1	0.7	1.2	3.8	-0.5	-1.5	1.9	0.6	-0.8	-0.3
Light reinforcement 2	0.4	0.5	1.6	-1.3	0.2	0.1	0.7	-0.5	-0.9
Reaction time number correct	0.7	1.0	3.0	1.7	-1.1	1.0	-0.7	0.4	0.3
Reaction time mean minus median	0.1	0.2	0.5	-0.7	0.2	0.0	0.1	0.0	-0.6
Reaction time mean minus median AUC	0.1	0.2	0.3	-0.1	-0.5	0.5	-0.5	0.5	0.3
Reaction time num false alarms	3.2	4.4	7.1	1.2	-2.7	2.6	-1.9	1.9	2.0
Reaction time num false alarms AUC	1.8	2.6	5.2	0.7	-2.2	2.3	-1.3	1.3	1.3
Reaction time trials correct on left	0.7	1.0	3.0	1.7	-1.1	1.0	-0.7	0.4	0.3
Reaction time trials on left	0.8	1.1	3.1	1.7	-1.2	1.0	-0.7	0.4	0.3
Reaction time mean	0.7	1.0	1.8	-1.4	0.3	0.1	1.1	-1.1	-1.4
Reaction time mean AUC	0.6	0.8	1.5	-1.1	0.2	0.1	1.0	-0.9	-1.2
Median of all reaction times	0.9	1.2	1.9	-1.3	0.3	0.1	1.3	-1.2	-1.4
Reaction time omissions	0.1	0.1	0.2	-0.5	-0.1	0.3	-0.0	0.1	-0.3
Reaction time false alarm rate	1.2	1.7	3.1	0.2	-1.7	1.7	-1.2	1.2	1.3
Reaction time premature initiation rate	0.4	0.6	0.9	0.5	0.4	-0.8	-0.8	1.0	0.9
Reaction time premature initiations	0.6	0.9	1.6	1.3	-0.3	-0.1	-1.1	1.1	1.1
Std. dev. reaction times	0.9	1.3	2.4	-1.5	1.0	-0.7	1.0	-0.8	-1.5
Reaction time trials completed	0.8	1.1	3.1	1.7	-1.2	1.0	-0.7	0.4	0.3
Reaction time trials AUC	0.7	1.0	3.0	1.7	-1.2	1.1	-0.7	0.3	0.4
Social response proportion	2.6	2.8	6.1	-1.2	0.8	-0.4	2.2	-2.5	-1.9
Social responses	0.8	1.0	3.0	0.6	-1.6	1.7	-0.3	0.0	0.2
Social time	1.0	1.3	3.4	-1.0	0.2	0.1	1.7	-1.8	-0.7
Conditioned locomotion	5.6	6.7	10.6	-3.3	2.8	-2.4	2.6	-2.4	-2.0
Cocaine response after cond. corrected	0.3	0.3	0.4	0.6	-0.6	0.6	-0.6	0.6	0.2
Cocaine response after cond. not corrected	0.5	0.5	1.1	1.1	-0.8	0.8	-0.6	0.5	-0.0
Cocaine response before conditioning	1.0	1.2	3.5	0.9	-1.7	1.9	-0.2	-0.2	-0.2
Saline control response	0.7	0.9	1.6	1.0	-1.3	1.2	-0.5	0.2	0.9
Condit. Reinf. active minus inactive responses	2.0	2.5	4.1	1.1	-1.4	1.2	-1.9	2.0	1.7
Condit. Reinf. active-inactive response ratio	0.5	0.5	0.9	-0.2	-0.6	0.6	-0.8	0.9	0.9
Condit. Reinf. active responses	2.7	3.8	5.5	1.7	-1.8	1.6	-2.3	2.4	1.8
Condit. Reinf. inactive responses	1.4	1.7	2.6	1.6	-1.5	1.4	-1.3	1.2	0.6
Condit. Reinf. lever presses	1.4	2.0	2.7	1.6	-1.4	1.1	-1.5	1.4	1.4
Condit. Reinf. lever reinforcers received	3.7	5.2	7.7	2.2	-2.0	1.5	-2.7	2.8	2.2
Pavlov. Cond. lever latency	1.0	1.4	2.7	-1.6	0.8	-0.3	1.1	-1.0	-1.7
Pavlov. Cond. magazine entry latency	0.2	0.3	0.5	-0.3	0.3	-0.2	0.6	-0.6	-0.7
Pavlov. Cond. change in total contacts	0.5	0.7	1.6	0.9	-0.7	0.4	-0.7	0.7	1.2
Pavlov. Cond. index score	0.1	0.2	0.5	0.6	-0.2	-0.0	-0.4	0.3	0.7
Pavlov. Cond. latency score	0.1	0.1	0.3	0.3	-0.2	0.0	-0.2	0.2	0.5
Pavlov. Cond. lever contacts	0.4	0.5	1.1	1.1	-0.3	-0.1	-0.6	0.5	1.1
Pavlov. Cond. magazine entry number	0.1	0.1	0.3	-0.3	-0.4	0.6	-0.2	0.2	0.1
Pavlov. Cond. intertrial magazine entries	1.6	2.0	2.9	0.8	-1.4	1.4	-1.6	1.7	1.5
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.4	0.4	-0.2	-0.0	-0.2	0.2	0.7
Pavlov. Cond. response bias	0.5	0.7	1.6	1.3	-0.3	-0.1	-0.8	0.7	1.2
Conditioned reinforcement - actives	2.5	2.5	4.0	1.4	-1.2	0.9	-1.8	1.8	2.0
Conditioned reinforcement - inactives	2.8	3.1	6.1	1.4	-1.5	1.1	-1.9	1.9	2.5
Conditioned locomotion	1.1	1.3	3.3	1.0	-0.4	-0.0	-1.3	1.3	1.8
Intermittent access intake day 1-15 change	1.5	1.4	3.8	0.5	-1.8	1.9	-0.7	0.5	0.7
Intermittent access intake escalation	2.5	2.4	4.7	1.0	-2.1	2.2	-1.3	1.1	1.3
Intermittent access intake escalation 2	5.2	5.2	8.5	1.6	-2.9	2.9	-2.0	1.8	2.2
Intermitt. access day 1 inactive lever presses	0.3	0.3	0.7	-0.2	0.8	-0.8	0.3	-0.3	-0.7
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.9	-0.0	0.2	-0.1	0.3	-0.3	-1.0
Intermitt. access escalation Index	0.5	0.5	0.9	-0.8	-0.0	0.3	0.9	-0.9	-0.7
Intermittent access day 1 total infusions	0.5	0.6	2.0	-0.2	1.2	-1.4	0.2	-0.0	-0.1
Intermittent access day 15 total infusions	0.4	0.5	0.8	0.5	-0.6	0.4	-0.8	0.8	0.9
Intermittent access terminal intake (last 3 days)	0.4	0.4	1.0	0.5	-0.3	0.1	-0.7	0.7	1.0
Intermittent access total infusions	0.5	0.5	0.8	0.5	0.5	-0.8	-0.7	0.9	0.9
Intermittent access day 1 locomotion	0.6	0.6	1.1	0.5	0.4	-0.7	-0.8	0.9	1.1
Intermittent access day 15 total locomotion	1.2	1.3	2.3	1.2	-0.4	-0.0	-1.4	1.4	1.5
Intermittent access total locomotion	1.7	1.9	3.0	1.6	0.0	-0.6	-1.6	1.7	1.7
Intermittent access standard deviation	0.6	0.7	1.5	0.8	-1.2	1.2	-0.5	0.3	0.3
Cocaine induced anxiety	1.1	1.3	4.3	-0.2	-1.7	2.1	0.4	-0.6	-0.0
Post-drug Anxiety	0.1	0.1	0.4	-0.6	0.2	-0.1	0.2	-0.1	0.1
Baseline Anxiety	2.2	2.3	6.9	-0.7	2.4	-2.6	0.4	-0.1	-0.8
Lifetime Intake	0.6	0.7	1.0	0.6	0.6	-1.0	-0.8	1.0	1.0
Incentive Sensitization - Responses	0.2	0.2	0.7	-0.2	0.4	-0.3	0.2	-0.0	-0.9
Incentive Sensitization - Breakpoint	0.2	0.2	0.7	-0.3	0.3	-0.2	0.2	-0.1	-0.8
Progressive ratio test 1 active lever presses	1.9	2.0	4.1	1.5	-0.9	0.4	-1.6	1.5	2.0
Progressive ratio test 1 breakpoint	1.4	1.5	3.0	1.3	-0.7	0.3	-1.4	1.3	1.7
Progressive ratio test 1 inactive lever presses	1.1	1.2	2.4	1.1	-0.8	0.5	-1.2	1.1	1.6
Progressive ratio test 2 active lever presses	0.3	0.3	0.6	0.4	0.5	-0.7	-0.5	0.7	0.4
Progressive ratio test 2 breakpoint	0.2	0.2	0.5	0.1	0.6	-0.7	-0.3	0.5	0.2
Progressive ratio test 2 inactive lever presses	0.1	0.2	0.3	0.4	-0.1	-0.1	-0.5	0.6	0.5
Total sessions with >9 infusions	0.6	0.7	1.1	0.9	0.6	-1.0	-0.6	0.7	1.1
Short access day 1 total inactive lever presses	1.3	1.5	3.1	1.3	-0.2	-0.2	-1.4	1.5	1.8
Short access day 10 total inactive lever presses	0.6	0.7	2.4	-0.4	-1.2	1.6	-0.3	0.2	0.1
Short access day 1 total infusions	0.5	0.5	1.2	0.9	-0.0	-0.3	-0.7	0.7	1.1
Short access day 10 total infusions	1.0	1.1	1.5	0.9	0.6	-1.2	-1.1	1.2	1.2
Short access total infusions	0.9	1.0	1.6	1.0	0.0	-0.5	-1.2	1.2	1.3
Short access day 1 locomotion	1.2	1.3	2.4	1.5	0.1	-0.7	-1.2	1.3	1.3
Short access day 10 total locomotion	1.0	1.1	2.1	1.1	-0.2	-0.2	-1.2	1.3	1.4
Short access total locomotion	1.9	2.0	3.2	1.8	-0.6	0.1	-1.6	1.6	1.8
Compulsive drug intake	0.3	0.3	0.7	-0.8	0.8	-0.9	0.1	0.1	0.1
One hour access (0.3 mA shock)	0.5	0.6	1.7	0.3	-0.7	0.5	-0.6	0.7	1.3
One hour access (shock baseline)	0.1	0.1	0.3	0.5	-0.4	0.3	-0.3	0.2	0.5
Number of responses in last shaping day	0.2	0.2	0.4	0.5	0.3	-0.5	-0.5	0.6	0.4
Context. condit. distance diff. score	0.4	0.5	1.2	1.1	-0.7	0.4	-0.6	0.5	0.7
Locomotion velocity, session 1	1.1	1.2	2.4	-1.2	1.5	-1.5	0.7	-0.6	-0.5
Locomotion distance, session 1	0.4	0.5	1.0	-1.0	0.8	-0.7	0.6	-0.5	-0.5
Locomotion velocity, session 2	0.4	0.5	1.6	-1.3	0.7	-0.6	0.4	-0.2	-0.5
Locomotion distance, session 2	0.2	0.3	0.6	-0.8	0.8	-0.7	0.3	-0.1	-0.5
Locomotion velocity, session 3	0.3	0.4	1.1	0.0	-0.9	1.0	-0.4	0.3	0.2
Locomotion distance, session 3	1.1	1.2	2.6	1.0	-1.6	1.6	-0.7	0.5	0.4
Stereotopy head waving bouts, day 3	0.8	1.0	1.3	-1.1	0.9	-0.7	1.1	-1.1	-1.0
Stereotopy head waving duration, day 3	0.3	0.3	0.7	-0.8	0.8	-0.7	0.2	-0.1	-0.3
Locomotion velocity, session 7	1.1	1.2	3.5	0.8	-1.6	1.9	-0.4	0.1	-0.3
Locomotion distance, session 7	1.3	1.6	5.3	0.6	-1.9	2.3	-0.0	-0.3	-0.4
Stereotopy head waving bouts, day 7	0.0	0.0	0.0	0.1	0.1	-0.1	0.1	-0.1	-0.0
Stereotopy head waving duration, day 7	0.3	0.3	0.6	-0.5	0.7	-0.7	0.4	-0.3	-0.7
Locomotion velocity, session 8	1.1	1.3	4.1	-0.3	1.7	-2.0	-0.2	0.7	-0.1
Locomotion distance, session 8	0.3	0.4	0.7	0.8	0.1	-0.5	-0.7	0.8	0.5
Degree of sensitization distance	0.2	0.2	0.4	0.3	-0.6	0.7	-0.2	0.2	0.1
Degree of sensitization stereotypy	0.2	0.2	0.3	0.5	-0.1	-0.0	-0.5	0.5	0.5
Condit. Reinf. active minus inactive responses	4.0	4.4	6.1	1.8	-2.1	1.8	-2.2	2.1	2.5
Condit. Reinf. active-inactive response ratio	2.5	2.7	3.9	1.4	-2.0	1.8	-1.5	1.3	1.8
Condit. Reinf. active responses	6.2	7.5	11.7	2.6	-2.1	1.4	-3.2	3.2	3.4
Condit. Reinf. inactive responses	1.7	2.0	3.8	1.2	0.1	-0.7	-1.8	2.0	1.8
Incentive salience index mean	6.1	7.3	10.7	2.5	-2.2	1.6	-3.1	3.1	3.3
Condit. Reinf. lever presses	4.4	5.9	8.7	2.4	-1.8	1.3	-2.9	3.0	2.8
Time in familiar zone, hab. session 1	0.1	0.1	0.2	0.0	-0.3	0.3	-0.1	0.0	0.5
Time in novel zone, hab. session 1	0.1	0.1	0.2	0.3	0.4	-0.4	-0.1	0.2	-0.5
Total zone transitions, hab. session 1	0.7	0.9	1.6	-1.0	0.9	-0.7	0.9	-0.8	-1.3
Total locomotion distance, hab. session 1	0.6	0.8	1.5	-1.0	0.2	0.1	1.1	-1.0	-1.2
Locomotion velocity, hab. session 1	0.4	0.5	1.2	-1.1	0.4	-0.2	0.8	-0.7	-0.8
Time in familiar zone, hab. session 2	1.5	1.5	2.7	-0.9	0.9	-0.6	1.5	-1.6	-1.5
Time in novel zone, hab. session 2	2.1	2.1	3.7	1.1	-1.0	0.6	-1.7	1.8	1.9
Total zone transitions, hab. session 2	0.1	0.1	0.3	-0.0	0.5	-0.5	-0.2	0.4	-0.2
Total locomotion distance, hab. session 2	0.2	0.3	0.7	-0.9	0.3	-0.2	0.5	-0.3	-0.5
Locomotion velocity, hab. session 2	0.3	0.4	0.9	-0.9	0.6	-0.5	0.6	-0.4	-0.7
Novel to familiar place preference ratio	0.1	0.1	0.2	-0.5	0.2	-0.1	-0.1	0.2	-0.2
Novelty place preference	0.1	0.1	0.2	-0.4	0.1	0.0	-0.3	0.5	0.0
Time in novel zone, NPP test	0.1	0.1	0.1	-0.3	-0.1	0.2	-0.3	0.3	0.0
Total zone transitions, NPP test	0.1	0.1	0.5	0.3	0.0	-0.1	-0.5	0.7	-0.0
Total locomotion distance, NPP test	0.1	0.1	0.2	-0.4	-0.1	0.2	0.2	-0.1	-0.5
Locomotion velocity, NPP test	0.0	0.0	0.1	-0.2	-0.1	0.1	-0.1	0.3	-0.2
Pavlov. Cond. lever latency	1.5	1.9	3.5	-1.4	0.8	-0.5	1.8	-1.9	-1.3
Pavlov. Cond. magazine entry latency	0.9	1.2	2.4	-1.2	0.8	-0.4	1.1	-1.1	-1.5
Pavlov. Cond. change in total contacts	0.1	0.1	0.3	-0.2	-0.4	0.5	-0.0	0.0	-0.0
Pavlov. Cond. index score	0.0	0.0	0.1	-0.2	0.0	0.0	-0.2	0.3	-0.3
Pavlov. Cond. latency score	0.1	0.1	0.3	0.0	0.1	-0.0	-0.4	0.5	-0.1
Pavlov. Cond. lever contacts	0.8	1.0	1.6	1.0	-0.8	0.6	-1.2	1.3	0.8
Pavlov. Cond. magazine entry number	0.7	0.9	1.6	1.0	-1.0	0.8	-0.8	0.6	1.3
Pavlov. Cond. intertrial magazine entries	1.4	1.7	3.2	0.8	-1.5	1.4	-1.1	0.9	1.8
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.2	-0.5	0.1	0.1	0.0	0.1	-0.4
Pavlov. Cond. response bias	0.2	0.3	0.5	-0.6	0.6	-0.4	0.4	-0.2	-0.7
Bone: apparent density	0.3	0.5	2.3	1.5	-0.7	0.5	-0.4	0.1	0.4
Bone surface	1.2	2.1	4.5	2.1	-1.7	1.5	-1.0	0.6	1.1
Bone volume	0.5	0.8	2.8	1.7	-0.8	0.5	-0.6	0.3	0.8
Bone: connectivity density	1.2	1.9	5.9	2.4	-1.2	0.8	-1.2	1.0	1.1
Bone: cortical apparent density	0.8	1.0	1.6	-1.3	1.0	-0.8	1.0	-0.9	-1.1
Bone: cortical area	0.9	1.4	3.0	1.3	-0.8	0.4	-1.3	1.2	1.7
Bone: cortical porosity	0.0	0.0	0.2	-0.4	0.2	-0.2	0.1	0.0	0.1
Bone: cortical porosity	0.2	0.2	0.5	0.2	-0.3	0.1	-0.6	0.6	0.7
Bone: cortical thickness	0.1	0.2	0.6	0.2	0.5	-0.8	-0.1	0.1	0.4
Bone: cortical thickness	0.8	1.0	2.1	-0.9	1.4	-1.5	0.6	-0.4	-0.6
Bone: cortical tissue density	0.8	1.0	1.6	-1.3	1.0	-0.7	1.0	-0.9	-1.1
Bone: elastic displacement	1.1	1.2	2.3	-0.8	1.4	-1.5	1.0	-0.9	-0.7
Bone: elastic work	0.2	0.3	0.7	0.8	-0.4	0.1	-0.3	0.2	0.8
Bone: endosteal estimation	1.3	2.8	4.6	1.1	-2.2	2.1	-1.3	1.1	1.8
Bone: endosteal perimeter	2.5	5.2	6.5	1.8	-2.5	2.3	-2.4	2.2	2.5
Bone: final force	0.1	0.2	0.3	0.3	-0.5	0.5	-0.1	-0.0	0.6
Bone: final moment	0.1	0.2	0.3	0.4	-0.5	0.4	-0.1	-0.0	0.6
Bone: marrow area	1.5	3.2	5.4	1.3	-2.3	2.3	-1.4	1.1	1.9
Bone: maximum diameter	4.3	7.9	13.0	2.4	-2.4	1.9	-3.1	3.0	3.6
Bone: maximum force	0.5	0.9	1.7	0.7	-1.3	1.3	-0.4	0.2	1.1
Bone: maximum moment	0.5	0.8	1.6	0.8	-1.2	1.2	-0.4	0.2	1.1
Bone: minimum diameter	1.6	2.9	3.6	1.6	-1.8	1.5	-1.8	1.6	1.9
Bone: periosteal estimation	1.5	3.1	5.1	1.5	-1.9	1.6	-1.7	1.5	2.3
Bone: periosteal perimeter	2.0	3.4	4.2	1.7	-2.1	1.9	-1.8	1.7	1.9
Bone: post-yield work	3.5	4.8	9.9	1.8	-3.1	3.1	-1.4	1.0	1.8
Bone: stiffness	0.1	0.1	0.4	0.2	-0.2	0.1	-0.4	0.3	0.6
Bone: tissue strength	0.1	0.1	0.4	0.1	-0.2	0.2	0.5	-0.6	-0.1
Bone: trabecular number	0.3	0.5	2.4	1.6	0.1	-0.5	-0.4	0.3	0.2
Bone: trabecular spacing	1.1	1.5	3.2	-1.8	0.8	-0.5	1.3	-1.2	-1.2
Bone: trabecular thickness	0.2	0.3	0.6	0.7	0.5	-0.8	-0.4	0.4	0.5
Bone: trabecular tissue density	0.7	1.0	3.1	-1.8	0.9	-0.7	0.9	-0.7	-0.6
Breakpoint value in progressive ratio session	1.9	2.1	4.0	2.0	-1.6	1.3	-1.4	1.2	1.2
Distance traveled before self-admin	2.2	2.4	3.8	0.7	-1.7	1.6	-1.5	1.5	1.9
Distance traveled after self-admin	1.3	1.4	3.2	0.3	-1.6	1.8	-0.8	0.6	1.3
Delta time in closed arm before/after self-admin	1.7	1.7	5.5	-0.3	2.1	-2.3	0.4	0.0	-0.4
Delta time in open arm before/after self-admin	0.3	0.2	0.5	-0.7	0.3	-0.3	0.6	-0.6	-0.2
Diff in mean of infusions in LGA sessions	0.3	0.4	0.7	0.6	-0.8	0.9	-0.4	0.4	0.3
Extinction: sum of active levers before priming	0.5	0.5	1.6	1.3	-0.4	0.2	-0.8	0.8	0.2
Active lever presses in extinction session 6	2.1	2.0	3.6	1.7	0.2	-0.8	-1.7	1.9	1.3
Delta distance traveled before/after self-admin	0.5	0.5	1.0	-0.6	-0.0	0.4	0.8	-0.9	-1.0
Delta ambulatory time before/after self-admin	0.6	0.7	1.3	-0.9	-0.2	0.6	1.0	-1.1	-0.8
Time in closed arm before self-admin	1.8	2.1	7.1	0.3	-2.2	2.7	-0.5	0.2	0.1
Time in closed arm after self-admin	0.2	0.2	0.6	0.3	-0.2	0.2	-0.7	0.8	0.1
Time in open arm before self-admin	0.6	0.6	1.5	-0.0	1.1	-1.2	0.6	-0.5	-0.6
Time in open arm after self-admin	0.9	0.9	1.3	-0.9	1.1	-1.2	1.0	-0.9	-0.7
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.2	0.5	-0.3	0.3	-0.3	0.2	0.4
Time to tail flick, vehicle, before self-admin	0.7	0.7	1.0	1.0	-0.8	0.6	-0.9	0.9	0.8
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.3	0.2	-0.0	0.0	0.0	-0.1	-0.6
Time to tail flick, test, before self-admin	0.7	0.7	2.4	-0.2	-1.3	1.5	0.1	-0.2	-0.2
Time to tail flick, test, after self-admin	0.1	0.1	0.4	0.5	-0.2	0.1	0.4	-0.6	-0.1
Delta time to tail flick, vehicle, before/after SA	0.8	0.8	1.9	-0.7	0.8	-0.7	0.8	-0.8	-1.4
Delta time to tail flick, test, before/after SA	1.6	1.5	2.4	-0.5	1.2	-1.2	1.4	-1.5	-1.0
Ambulatory time before self-admin	1.9	1.9	2.6	0.9	-1.4	1.3	-1.5	1.4	1.6
Ambulatory time after self-admin	1.1	1.2	2.8	0.4	-1.5	1.7	-0.7	0.5	1.1
Total heroin consumption	0.2	0.2	0.5	0.7	0.2	-0.5	-0.5	0.5	0.2
Area under the delay curve	0.2	0.2	0.8	-0.1	-0.7	0.9	0.2	-0.2	-0.2
Delay disc. indifference point, 0s delay	0.2	0.2	0.4	0.4	-0.2	0.1	-0.5	0.5	0.6
Delay disc. indifference point, 16s delay	0.3	0.3	0.5	0.6	-0.7	0.7	-0.5	0.4	0.4
Delay disc. indifference point, 2s delay	0.3	0.3	1.0	-0.0	-0.8	1.0	0.3	-0.5	-0.2
Delay disc. indifference point, 24s delay	0.1	0.1	0.1	-0.4	0.2	-0.1	0.3	-0.2	-0.1
Delay disc. indifference point, 4s delay	0.8	0.8	1.1	-1.0	0.9	-0.6	0.9	-0.8	-1.1
Delay disc. indifference point, 8s delay	0.6	0.6	1.7	0.2	-1.0	1.3	0.4	-0.6	-0.7
Delay discount exponential model param	0.2	0.2	0.4	0.4	0.4	-0.6	-0.4	0.4	0.5
Delay discount hyperbolic model param	0.3	0.3	0.5	0.5	0.4	-0.7	-0.5	0.6	0.6
Fecal boli incidents, locomotor time 1	3.3	3.5	6.3	1.3	-2.5	2.4	-1.2	0.9	2.2
Change in fecal boli incidents, locomotor task	0.3	0.3	0.9	0.2	0.6	-0.6	0.2	-0.1	-0.9
Time >=10cm from walls, locomotor time 1	1.6	1.6	2.5	-1.5	0.9	-0.7	1.5	-1.6	-1.1
Bouts of movement, locomotor time 1	0.6	0.7	1.4	-1.0	1.0	-1.2	0.3	-0.1	0.8
Total resting periods, locomotor time 1	0.8	0.9	1.8	-1.2	1.2	-1.3	0.5	-0.3	0.6
Rest time, locomotor task time 1	0.6	0.6	2.5	-0.0	-0.4	0.3	-0.7	0.8	1.6
Distance moved, locomotor task time 1	0.6	0.7	2.3	0.0	0.7	-0.6	0.6	-0.6	-1.5
Vertical activity count, locomotor time 1	0.3	0.3	0.8	0.5	-0.3	0.3	0.4	-0.5	-0.9
Time >=10cm from walls, locomotor time 2	2.2	2.3	4.2	-1.9	0.8	-0.4	2.0	-2.1	-1.2
Bouts of movement, locomotor time 2	0.7	0.7	1.3	-1.0	0.1	0.3	1.0	-1.0	-1.1
Total resting periods, locomotor time 2	1.1	1.1	1.9	-1.2	0.4	0.0	1.3	-1.3	-1.4
Rest time, locomotor task time 2	0.2	0.2	0.6	-0.8	0.2	-0.1	0.6	-0.6	-0.1
Distance moved, locomotor task time 2	0.0	0.0	0.1	0.2	-0.1	0.0	-0.0	0.0	-0.3
Vertical activity count, locomotor time 2	0.6	0.7	1.4	-0.4	-0.6	0.9	0.9	-1.2	-0.8
Weight adjusted by age	0.4	0.5	0.9	0.8	-0.9	0.9	-0.3	0.0	0.6
Seeking ratio, delayed vs. immediate footshock	1.9	2.2	4.9	-1.3	1.0	-0.6	1.6	-1.6	-2.2
Locomotion in novel chamber	0.2	0.2	0.6	-0.8	0.4	-0.2	0.4	-0.4	0.1
Locomotion in novel chamber post-restriction	0.2	0.3	0.8	-0.4	0.3	-0.3	-0.6	0.9	0.2
Progressive ratio	0.7	0.8	1.7	-1.3	0.8	-0.6	0.9	-0.8	-0.6
Food seeking constrained by brief footshock	1.0	1.2	2.0	-1.4	0.0	0.4	1.4	-1.4	-1.1
Seeking ratio, punishment vs. effort	0.2	0.3	0.7	0.0	-0.6	0.8	0.3	-0.4	-0.5
Run reversals in cocaine runway, females	4.6	4.6	7.3	-2.7	2.2	-1.8	2.2	-2.1	-1.8
Run reversals in cocaine runway, males	0.4	0.4	0.8	0.5	0.4	-0.7	-0.7	0.9	0.5
Latency to leave start box in cocaine runway	1.5	1.7	3.6	-0.6	1.4	-1.3	1.1	-1.1	-1.9
Latency to leave start box in cocaine runway, F	1.5	1.6	5.6	-0.3	0.4	-0.0	1.3	-1.5	-2.4
Latency to leave start box in cocaine runway, M	1.4	1.3	4.3	-0.5	1.8	-2.1	0.2	0.1	-0.1
Cd content in liver	0.1	0.2	0.5	0.0	-0.6	0.7	-0.0	-0.0	0.3
Co content in liver	7.1	8.3	10.3	2.7	-3.0	2.5	-3.0	2.8	3.2
Cu content in liver	0.2	0.3	0.4	-0.6	-0.3	0.5	0.5	-0.6	-0.6
Fe content in liver	1.4	1.7	2.5	0.9	-1.6	1.5	-1.2	1.2	1.4
K content in liver	0.3	0.3	0.9	-0.1	-0.3	0.3	-0.8	0.9	0.1
Mg content in liver	0.2	0.2	0.6	-0.1	0.0	-0.0	-0.6	0.7	0.1
Mn content in liver	0.6	0.6	2.0	-0.9	-1.0	1.4	0.0	-0.0	-0.2
Na content in liver	0.3	0.3	0.6	0.8	-0.3	0.1	-0.7	0.7	0.2
Rb content in liver	0.8	1.0	1.9	-1.4	1.1	-0.9	0.9	-0.7	-0.7
Se content in liver	0.2	0.2	0.9	-0.9	0.0	0.2	-0.0	0.3	-0.6
Sr content in liver	0.4	0.4	0.7	-0.3	0.8	-0.8	0.5	-0.4	-0.6
Zn content in liver	0.6	0.6	1.4	0.3	-0.6	0.6	-1.0	1.2	0.7