Hub : Genes

ENSRNOG00000067823

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Adipose	gene expression	ENSRNOG00000067823	0.19	0.09	1.2e-04	-0	0.02	0.02	0.01	6.0e-01	1.2e-03	4.7e-03	2.6e-02
2	Brain	gene expression	ENSRNOG00000067823	0.14	0.06	5.9e-15	0.12	0.15	0.15	0.14	8.7e-11	2.1e-13	1.0e-13	3.5e-13
3	Liver	gene expression	ENSRNOG00000067823	0.52	0.1	0.0e+00	0.13	0.22	0.2	0.22	1.1e-14	9.7e-24	5.3e-22	8.8e-24
4	OFC	gene expression	ENSRNOG00000067823	0.43	0.15	3.1e-05	0.07	0.07	0.05	0.06	7.7e-03	8.2e-03	2.8e-02	1.6e-02
5	PL	gene expression	ENSRNOG00000067823	0.07	0.05	3.5e-04	0.03	0.04	0.05	0.04	3.8e-03	5.3e-04	1.0e-04	3.2e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strong Z-scores (below -2 or above 2): lower negative Z-scores are darker blue, higher positive Z-scores are darker red.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
BMI with tail	0.8	2.7	5.3	-0.4	-2.3	-1.8	-1.8	-1.4
BMI without tail	1.9	3.9	10.1	-1.9	-3.2	-1.6	-1.7	-0.8
Body weight	2.4	10.0	19.5	0.8	-4.4	0.7	-3.7	-3.9
Epididymis fat weight	1.2	2.8	5.2	1.3	-2.1	0.0	-2.3	-1.7
Glucose	0.3	0.4	1.0	1.0	0.9	0.1	0.1	0.2
Heart weight	3.3	4.8	6.4	2.5	-1.0	2.2	-2.4	-2.4
Left kidney weight	0.2	0.5	0.8	0.9	-0.5	0.4	-0.8	-0.9
Right kidney weight	0.8	2.2	3.9	1.0	-1.5	1.0	-1.7	-2.0
Tail length	1.0	3.0	7.1	-0.1	-2.7	1.3	-2.0	-1.5
Length with tail	2.3	8.3	10.7	2.3	-2.7	3.1	-3.0	-3.3
Length without tail	1.1	2.5	5.5	2.4	-0.2	1.6	-1.1	-1.8
Liver weight, left	0.3	0.4	1.1	-0.7	0.4	-0.4	1.1	0.4
Liver weight, right	1.2	1.9	3.0	-1.1	1.0	-1.3	1.6	1.7
Parametrial fat weight	0.8	1.6	4.2	-1.6	-0.2	-0.6	0.8	2.1
Retroperitoneal fat weight	1.7	5.5	12.0	0.6	-3.5	-0.1	-3.3	-2.1
Intraocular pressure	0.2	0.3	0.9	0.0	-0.5	0.0	-0.5	-0.9
Extensor digitorum longus weight	0.3	1.1	2.2	1.5	0.9	-1.1	-0.8	-0.9
Soleus weight	0.9	2.6	5.0	1.8	-0.7	1.1	-1.7	-2.2
Tibialis anterior weight	0.4	1.3	2.1	-0.1	-1.5	-1.0	-1.4	-1.2
Tibia length	1.4	3.9	5.6	2.2	-1.1	2.2	-1.8	-2.4
Number of licking bursts	0.8	1.0	1.9	1.1	-0.5	1.0	-0.8	-1.4
Food consumed during 24 hour testing period	2.1	2.5	5.9	-2.4	-1.2	-2.0	0.7	0.8
Times rat made contact with spout	0.4	0.5	1.1	-0.2	-1.1	0.3	-0.6	-0.8
Mean time between licks in bursts	1.9	2.6	3.8	1.9	-1.1	1.2	-1.9	-1.7
Mean num. licks in bursts	0.4	0.5	1.0	-1.0	-0.1	-0.8	0.4	1.0
Std. dev. time between licks in bursts	0.7	0.8	1.8	-0.6	0.4	-1.2	0.5	1.3
Water consumed over 24 hours	1.4	1.6	3.4	-1.8	-0.4	-1.7	1.0	0.8
Indifference point 0 sec	4.6	7.4	16.2	-0.2	-4.0	1.5	-2.7	-3.3
Indifference point AUC	0.6	0.7	1.4	-0.0	-1.2	0.4	-0.7	-1.1
Indifference point function ln k	1.0	1.5	2.3	-0.9	1.1	-1.1	1.4	1.5
Indifference point function log k	1.0	1.5	2.3	-0.9	1.1	-1.1	1.4	1.5
Delay discounting total patch changes 0 sec	4.3	7.0	14.9	-0.2	-3.9	1.5	-2.6	-3.3
Delay discounting total patch changes 12 sec	4.0	5.3	10.6	0.4	-3.3	2.0	-2.4	-2.4
Delay discounting total patch changes 18 sec	2.1	2.8	5.7	0.4	-2.2	0.8	-1.6	-2.4
Delay discounting total patch changes 24 sec	4.4	5.5	10.4	0.5	-3.1	1.4	-2.3	-3.2
Delay discounting total patch changes 6 sec	5.8	8.9	14.9	1.0	-3.9	2.4	-3.3	-3.4
Delay discounting time to switch 0 sec	0.1	0.2	0.5	0.7	0.4	0.4	-0.1	0.0
Delay discounting water rate 0 sec	0.7	1.2	3.9	-1.1	-2.0	-0.1	-1.0	0.2
Delay discounting water rate 12 sec	0.1	0.1	0.2	-0.1	-0.3	-0.5	-0.3	0.2
Delay discounting water rate 18 sec	0.6	0.7	1.5	-1.1	0.0	-1.2	0.7	0.6
Delay discounting water rate 24 sec	0.6	0.9	1.5	-0.0	1.1	-0.6	1.2	1.2
Delay discounting water rate 6 sec	1.5	2.2	5.1	-1.3	0.7	-1.7	1.0	2.2
Locomotor activity	1.1	1.8	4.9	-1.2	-2.2	-0.3	-0.9	-1.3
Locomotor testing distance	0.8	1.3	3.0	-1.3	-1.7	-0.7	-0.3	-1.2
Locomotor testing rearing	0.6	1.0	1.7	-1.3	-1.2	-1.0	-0.2	-0.9
Light reinforcement 1	1.6	2.9	6.4	-2.2	-0.1	-2.5	1.0	1.5
Light reinforcement 2	0.5	0.6	2.2	0.3	0.4	-0.6	0.5	1.5
Reaction time number correct	0.4	0.6	1.8	0.0	1.3	-0.3	0.6	0.7
Reaction time mean minus median	0.0	0.0	0.1	0.2	0.2	0.1	0.2	0.3
Reaction time mean minus median AUC	0.2	0.3	0.5	-0.3	0.4	0.2	0.7	0.7
Reaction time num false alarms	3.0	4.2	8.6	0.8	-2.0	1.8	-2.0	-2.9
Reaction time num false alarms AUC	3.2	4.4	8.7	0.5	-2.3	1.9	-2.1	-2.9
Reaction time trials correct on left	0.4	0.6	1.8	0.0	1.3	-0.3	0.6	0.7
Reaction time trials on left	0.4	0.5	1.6	0.0	1.3	-0.2	0.6	0.8
Reaction time mean	0.6	0.9	2.2	-0.0	0.8	0.6	1.1	1.5
Reaction time mean AUC	0.7	0.9	2.3	-0.4	0.8	0.3	1.2	1.5
Median of all reaction times	0.8	1.1	3.0	-0.2	0.7	0.6	1.2	1.7
Reaction time omissions	0.2	0.2	0.5	0.0	-0.7	0.7	-0.3	0.5
Reaction time false alarm rate	3.1	4.4	8.3	0.6	-2.4	1.7	-2.1	-2.9
Reaction time premature initiation rate	0.9	1.2	2.6	0.9	-1.6	0.7	-1.2	-0.8
Reaction time premature initiations	0.2	0.2	0.5	0.5	-0.7	0.3	-0.5	-0.1
Std. dev. reaction times	0.2	0.3	0.5	0.2	0.3	0.7	0.4	0.7
Reaction time trials completed	0.4	0.5	1.6	0.0	1.3	-0.2	0.6	0.8
Reaction time trials AUC	0.4	0.5	1.7	-0.1	1.3	-0.3	0.6	0.7
Social response proportion	0.3	0.3	0.6	-0.1	-0.5	0.5	-0.6	0.8
Social responses	1.3	1.7	4.6	-0.6	-2.1	0.7	-1.6	-0.8
Social time	0.8	1.0	2.1	1.4	0.1	1.3	-1.1	-0.1
Conditioned locomotion	0.3	0.4	0.8	-0.9	0.0	-0.7	0.3	0.6
Cocaine response after cond. corrected	0.7	0.8	2.0	1.4	0.3	1.2	-0.6	-0.1
Cocaine response after cond. not corrected	1.3	1.4	3.4	1.8	0.6	1.6	-0.7	-0.5
Cocaine response before conditioning	0.2	0.2	0.3	0.6	0.5	0.4	0.1	-0.5
Saline control response	0.8	1.0	1.7	-1.1	-1.3	-1.3	-0.7	-0.3
Condit. Reinf. active minus inactive responses	3.5	4.3	6.3	0.5	-2.5	2.4	-2.2	-2.1
Condit. Reinf. active-inactive response ratio	4.1	4.3	5.6	1.0	-2.0	2.4	-2.3	-2.3
Condit. Reinf. active responses	3.2	4.4	8.7	0.1	-3.0	2.1	-2.2	-2.1
Condit. Reinf. inactive responses	0.8	1.0	2.4	-1.6	-1.4	-0.5	0.0	0.3
Condit. Reinf. lever presses	2.4	3.3	8.5	-0.8	-2.9	0.9	-2.0	-1.6
Condit. Reinf. lever reinforcers received	3.2	4.5	8.7	0.1	-2.9	2.1	-2.2	-2.1
Pavlov. Cond. lever latency	0.3	0.4	0.9	0.2	0.9	-0.7	0.7	0.5
Pavlov. Cond. magazine entry latency	0.7	0.8	1.9	1.4	1.3	0.7	-0.0	0.3
Pavlov. Cond. change in total contacts	0.2	0.3	0.9	0.3	-0.2	0.9	-0.4	-0.5
Pavlov. Cond. index score	0.5	0.6	1.2	0.7	-0.4	1.1	-0.9	-0.7
Pavlov. Cond. latency score	0.5	0.7	1.5	0.9	-0.2	1.2	-0.8	-0.7
Pavlov. Cond. lever contacts	0.3	0.4	1.0	-0.8	-1.0	0.1	-0.4	-0.1
Pavlov. Cond. magazine entry number	0.8	1.0	2.4	-1.5	-1.5	-0.6	-0.1	-0.0
Pavlov. Cond. intertrial magazine entries	2.2	2.8	7.4	-2.4	-2.7	-0.6	-0.5	-0.2
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	1.3	0.8	-0.3	1.1	-0.8	-0.7
Pavlov. Cond. response bias	0.1	0.1	0.3	-0.2	-0.5	0.4	-0.4	-0.1
Conditioned reinforcement - actives	2.0	1.9	4.8	-2.2	-0.0	-1.2	1.5	1.1
Conditioned reinforcement - inactives	1.3	1.5	3.5	0.4	-1.5	0.7	-1.2	-1.9
Conditioned locomotion	1.2	1.4	4.7	-0.4	-2.2	0.5	-1.1	-0.9
Intermittent access intake day 1-15 change	3.0	3.0	5.1	1.6	-1.1	1.8	-2.3	-1.7
Intermittent access intake escalation	3.5	3.5	4.8	1.9	-1.0	2.0	-2.2	-2.0
Intermittent access intake escalation 2	3.6	3.6	5.1	1.4	-1.7	2.0	-2.3	-1.9
Intermitt. access day 1 inactive lever presses	2.0	2.2	4.2	0.6	-2.1	1.1	-1.9	-1.2
Intermitt. access day 15 inactive lever presses	0.7	0.7	1.7	0.4	-1.3	0.0	-1.2	-0.6
Intermitt. access escalation Index	0.4	0.3	1.2	-0.3	1.1	0.1	0.5	-0.0
Intermittent access day 1 total infusions	0.4	0.5	1.2	-0.9	-1.1	-0.3	-0.1	-0.6
Intermittent access day 15 total infusions	3.2	3.6	5.3	0.9	-2.1	1.6	-2.2	-2.3
Intermittent access terminal intake (last 3 days)	3.5	3.8	6.7	0.4	-2.6	1.6	-2.2	-2.3
Intermittent access total infusions	2.3	2.5	5.5	-0.1	-2.3	1.0	-1.6	-1.8
Intermittent access day 1 locomotion	3.7	3.8	7.0	0.7	-2.6	1.1	-2.3	-2.3
Intermittent access day 15 total locomotion	4.5	4.8	9.8	0.5	-3.1	1.5	-2.6	-2.1
Intermittent access total locomotion	6.5	7.3	17.4	0.4	-4.2	1.4	-3.3	-2.5
Intermittent access standard deviation	4.9	5.3	7.6	1.8	-2.2	1.9	-2.7	-2.8
Cocaine induced anxiety	0.8	1.0	2.0	-0.6	0.7	-0.6	1.4	1.3
Post-drug Anxiety	1.4	1.5	3.2	0.4	1.4	-0.4	1.5	1.8
Baseline Anxiety	1.3	1.4	1.9	-0.3	1.4	-1.3	1.3	1.4
Lifetime Intake	2.0	2.2	5.7	-0.6	-2.4	0.4	-1.4	-1.7
Incentive Sensitization - Responses	0.1	0.1	0.2	0.2	0.1	0.5	0.3	-0.3
Incentive Sensitization - Breakpoint	0.1	0.1	0.3	0.3	0.1	0.5	0.3	-0.2
Progressive ratio test 1 active lever presses	2.1	2.2	6.3	-1.4	-2.5	0.0	-1.1	-1.2
Progressive ratio test 1 breakpoint	2.4	2.5	7.4	-1.6	-2.7	-0.1	-1.2	-1.0
Progressive ratio test 1 inactive lever presses	2.3	2.4	6.7	-0.8	-2.6	0.4	-1.8	-1.2
Progressive ratio test 2 active lever presses	1.1	1.2	2.5	-0.1	-1.6	0.9	-0.8	-1.3
Progressive ratio test 2 breakpoint	1.0	1.1	2.8	-0.5	-1.7	0.8	-0.9	-1.0
Progressive ratio test 2 inactive lever presses	1.3	1.5	3.9	0.0	-2.0	1.0	-1.3	-1.0
Total sessions with >9 infusions	0.5	0.6	1.3	-0.5	-1.1	-0.3	-0.3	-1.1
Short access day 1 total inactive lever presses	0.1	0.1	0.1	0.1	-0.4	-0.3	-0.3	-0.4
Short access day 10 total inactive lever presses	1.2	1.3	3.3	0.8	-1.3	0.7	-1.8	-0.8
Short access day 1 total infusions	0.5	0.5	1.0	-1.0	-0.7	-1.0	0.4	-0.4
Short access day 10 total infusions	3.3	3.6	9.9	-1.3	-3.1	-0.2	-1.8	-1.8
Short access total infusions	1.8	2.0	5.0	-1.4	-2.2	-0.4	-0.9	-1.3
Short access day 1 locomotion	1.5	1.6	3.9	-1.6	-2.0	-1.0	-0.4	-0.5
Short access day 10 total locomotion	5.8	6.3	15.2	0.6	-3.9	1.3	-2.7	-2.7
Short access total locomotion	3.4	3.5	10.5	-0.7	-3.2	0.0	-2.0	-1.5
Compulsive drug intake	1.1	1.1	2.3	1.2	-0.2	1.5	-0.8	-0.9
One hour access (0.3 mA shock)	1.8	2.1	4.0	-0.1	-2.0	1.2	-1.4	-1.7
One hour access (shock baseline)	0.5	0.5	1.5	-0.7	-1.2	0.1	-0.8	-0.4
Number of responses in last shaping day	0.9	0.9	2.8	0.4	-0.9	0.1	-1.0	-1.7
Context. condit. distance diff. score	0.2	0.2	0.6	0.7	-0.1	0.3	-0.5	-0.3
Locomotion velocity, session 1	0.1	0.1	0.2	-0.3	-0.3	-0.0	0.0	-0.4
Locomotion distance, session 1	0.0	0.1	0.2	-0.1	-0.1	-0.2	0.2	-0.4
Locomotion velocity, session 2	1.2	1.4	3.8	-1.9	0.1	-1.1	1.2	0.8
Locomotion distance, session 2	0.9	1.3	2.5	-1.6	0.4	-1.3	1.3	0.7
Locomotion velocity, session 3	0.8	0.9	1.8	-0.3	1.4	-1.1	1.0	0.7
Locomotion distance, session 3	0.5	0.6	1.1	1.1	0.4	0.9	-0.2	-0.8
Stereotopy head waving bouts, day 3	6.1	7.3	12.1	-1.7	2.6	-2.3	3.1	3.5
Stereotopy head waving duration, day 3	2.9	3.5	6.1	-0.7	2.1	-1.3	2.1	2.5
Locomotion velocity, session 7	0.4	0.5	1.0	-0.4	0.6	-1.0	0.6	0.6
Locomotion distance, session 7	0.5	0.7	1.1	0.7	-0.6	0.8	-1.0	-0.9
Stereotopy head waving bouts, day 7	3.5	4.0	5.8	-1.1	2.2	-1.8	2.2	2.4
Stereotopy head waving duration, day 7	4.8	5.9	9.7	-1.1	3.1	-1.7	2.8	2.8
Locomotion velocity, session 8	0.2	0.3	1.2	-0.0	-0.3	0.1	-0.3	-1.1
Locomotion distance, session 8	0.1	0.1	0.4	-0.6	-0.2	-0.4	0.2	-0.1
Degree of sensitization distance	0.1	0.1	0.5	-0.3	-0.7	-0.0	-0.4	0.0
Degree of sensitization stereotypy	1.9	2.0	2.7	-0.8	1.7	-1.4	1.4	1.6
Condit. Reinf. active minus inactive responses	4.5	5.0	6.3	1.5	-2.2	2.5	-2.4	-2.5
Condit. Reinf. active-inactive response ratio	1.6	1.8	3.3	1.2	-0.9	1.8	-1.2	-1.4
Condit. Reinf. active responses	3.3	4.1	5.1	1.0	-2.2	2.1	-2.2	-2.2
Condit. Reinf. inactive responses	0.3	0.4	0.9	-0.2	-1.0	0.3	-0.6	-0.7
Incentive salience index mean	1.9	2.3	3.5	0.6	-1.8	1.4	-1.6	-1.9
Condit. Reinf. lever presses	0.2	0.2	0.5	-0.2	-0.4	-0.5	-0.4	-0.7
Time in familiar zone, hab. session 1	3.1	3.0	5.4	1.0	-1.5	1.6	-1.8	-2.3
Time in novel zone, hab. session 1	2.7	2.6	4.9	-1.5	0.9	-1.8	1.4	2.2
Total zone transitions, hab. session 1	0.4	0.6	1.0	-0.8	-1.0	-0.9	-0.3	-0.7
Total locomotion distance, hab. session 1	1.2	1.7	4.1	-2.0	-1.2	-1.6	0.4	-0.1
Locomotion velocity, hab. session 1	0.8	1.2	2.9	-1.7	-1.0	-1.3	0.5	-0.1
Time in familiar zone, hab. session 2	1.6	1.7	2.7	0.7	-1.3	1.3	-1.3	-1.6
Time in novel zone, hab. session 2	3.1	3.1	6.0	-1.4	1.4	-1.5	1.9	2.4
Total zone transitions, hab. session 2	0.6	0.8	2.5	-1.1	-0.2	-1.6	0.3	0.0
Total locomotion distance, hab. session 2	1.7	2.3	4.8	-2.1	-0.5	-2.2	1.0	0.9
Locomotion velocity, hab. session 2	1.9	2.6	5.3	-2.2	-0.2	-2.3	1.3	1.2
Novel to familiar place preference ratio	3.1	3.2	4.3	1.0	-2.0	1.6	-2.0	-2.1
Novelty place preference	2.1	2.2	3.2	0.9	-1.7	1.2	-1.7	-1.8
Time in novel zone, NPP test	1.6	1.7	2.3	0.7	-1.5	1.1	-1.5	-1.5
Total zone transitions, NPP test	1.3	1.8	3.4	-1.8	0.2	-1.8	1.2	1.0
Total locomotion distance, NPP test	2.8	3.9	9.0	-3.0	-0.2	-2.3	1.6	1.5
Locomotion velocity, NPP test	1.8	2.6	5.4	-2.3	-0.1	-2.0	1.4	1.2
Pavlov. Cond. lever latency	1.0	1.3	3.0	0.1	1.5	0.1	1.2	1.7
Pavlov. Cond. magazine entry latency	1.7	2.2	3.9	0.4	-2.0	1.1	-1.7	-1.7
Pavlov. Cond. change in total contacts	1.9	2.1	3.9	0.0	-1.8	0.6	-1.6	-2.0
Pavlov. Cond. index score	1.5	1.9	3.3	0.2	-1.8	0.7	-1.6	-1.7
Pavlov. Cond. latency score	1.5	1.9	3.2	0.4	-1.7	0.6	-1.7	-1.8
Pavlov. Cond. lever contacts	1.1	1.3	3.4	0.2	-1.2	-0.3	-1.2	-1.8
Pavlov. Cond. magazine entry number	1.2	1.5	2.1	-0.4	1.4	-1.2	1.3	1.4
Pavlov. Cond. intertrial magazine entries	3.3	4.0	5.0	1.4	-2.2	1.8	-2.2	-2.1
Pavlov. Cond. lever-magazine prob. diff.	1.3	1.6	2.7	0.2	-1.6	0.6	-1.5	-1.6
Pavlov. Cond. response bias	1.2	1.4	3.0	0.1	-1.5	0.6	-1.2	-1.7
Bone: apparent density	0.1	0.2	0.4	-0.5	-0.5	0.1	-0.0	-0.6
Bone surface	1.6	2.8	4.9	-0.1	-2.2	1.6	-1.4	-2.2
Bone volume	1.9	3.3	5.4	0.5	-2.1	1.8	-1.7	-2.3
Bone: connectivity density	0.9	1.3	4.2	-2.0	-0.1	-0.8	1.2	0.5
Bone: cortical apparent density	4.4	5.7	12.5	-1.4	1.9	-2.5	2.1	3.5
Bone: cortical area	1.1	1.7	5.2	-1.0	-2.3	-0.2	-1.3	-0.7
Bone: cortical porosity	2.7	2.9	5.5	-0.2	-2.2	1.1	-1.8	-2.3
Bone: cortical porosity	3.7	4.0	7.6	0.7	-2.2	1.6	-2.1	-2.8
Bone: cortical thickness	4.0	6.7	13.5	-2.3	1.1	-3.7	1.8	3.2
Bone: cortical thickness	4.8	5.7	9.6	-2.7	0.6	-3.1	1.8	2.7
Bone: cortical tissue density	4.2	5.5	11.9	-1.3	1.9	-2.4	2.1	3.5
Bone: elastic displacement	1.2	1.3	2.3	-0.7	1.3	-1.1	1.5	1.0
Bone: elastic work	0.5	0.7	1.6	-1.2	-0.5	-1.3	0.5	0.1
Bone: endosteal estimation	13.3	28.6	42.9	1.9	-6.1	5.5	-5.4	-6.6
Bone: endosteal perimeter	13.2	27.2	38.4	2.6	-5.6	5.7	-5.2	-6.2
Bone: final force	0.8	1.3	3.7	-0.6	-1.9	0.5	-1.1	-0.9
Bone: final moment	0.8	1.3	3.8	-0.7	-1.9	0.4	-1.0	-0.9
Bone: marrow area	12.7	27.4	40.9	1.8	-6.0	5.4	-5.3	-6.4
Bone: maximum diameter	3.9	7.1	9.7	0.9	-3.1	2.9	-2.7	-3.0
Bone: maximum force	1.9	3.3	7.6	-0.1	-2.8	1.1	-1.9	-2.0
Bone: maximum moment	1.9	3.3	7.8	-0.2	-2.8	1.1	-1.8	-2.0
Bone: minimum diameter	9.8	18.1	29.4	1.2	-5.4	3.9	-4.5	-4.9
Bone: periosteal estimation	8.3	16.9	29.9	0.6	-5.5	3.6	-4.4	-4.6
Bone: periosteal perimeter	7.1	11.8	15.8	2.2	-3.4	3.6	-3.7	-4.0
Bone: post-yield work	3.7	5.0	7.9	1.3	-2.2	2.1	-2.5	-2.8
Bone: stiffness	1.0	1.6	3.6	-0.0	-1.9	1.0	-1.3	-1.3
Bone: tissue strength	1.6	1.5	3.0	-0.3	1.7	-0.8	1.7	1.0
Bone: trabecular number	0.2	0.3	1.1	-1.0	-0.1	-0.1	0.7	0.1
Bone: trabecular spacing	0.0	0.1	0.2	0.4	0.3	-0.1	-0.2	-0.0
Bone: trabecular thickness	0.8	1.0	2.2	0.1	-1.5	0.8	-1.2	-0.7
Bone: trabecular tissue density	0.1	0.2	0.6	0.3	0.4	-0.1	0.1	0.8
Breakpoint value in progressive ratio session	0.9	1.0	1.6	-0.4	0.9	-0.9	1.2	1.3
Distance traveled before self-admin	0.7	0.8	2.3	0.8	1.5	0.6	0.7	-0.3
Distance traveled after self-admin	0.3	0.3	1.1	0.2	1.1	0.2	0.7	-0.2
Delta time in closed arm before/after self-admin	0.3	0.3	0.5	0.7	0.5	0.5	0.4	0.4
Delta time in open arm before/after self-admin	1.6	1.5	2.7	-0.9	1.3	-1.1	1.6	1.1
Diff in mean of infusions in LGA sessions	0.2	0.2	0.9	0.0	0.3	-0.9	0.1	0.4
Extinction: sum of active levers before priming	0.2	0.2	0.5	-0.3	0.2	-0.7	0.3	0.3
Active lever presses in extinction session 6	0.6	0.6	1.3	-1.2	-1.1	-0.4	0.1	-0.1
Delta distance traveled before/after self-admin	1.8	1.9	3.6	-1.9	0.2	-1.9	1.0	1.2
Delta ambulatory time before/after self-admin	1.1	1.2	3.2	-1.8	-0.4	-1.1	0.7	1.0
Time in closed arm before self-admin	0.8	0.9	3.2	-1.8	-0.5	-0.8	0.2	0.4
Time in closed arm after self-admin	0.0	0.0	0.1	-0.2	-0.2	0.3	-0.1	-0.3
Time in open arm before self-admin	2.7	2.9	7.2	2.7	0.2	1.3	-1.6	-1.7
Time in open arm after self-admin	0.9	1.0	3.5	1.9	0.8	0.6	-0.4	-0.7
Sum of active levers in priming session hrs 5-6	0.1	0.1	0.2	-0.0	-0.3	0.4	-0.2	-0.4
Time to tail flick, vehicle, before self-admin	3.5	3.5	7.0	2.6	0.7	2.4	-0.7	-2.0
Time to tail flick, vehicle, after self-admin	0.9	1.0	3.0	1.2	-0.1	1.7	-0.3	-0.7
Time to tail flick, test, before self-admin	1.9	1.9	3.8	1.3	-0.8	2.0	-1.4	-1.1
Time to tail flick, test, after self-admin	0.8	0.8	1.8	0.1	-1.0	1.3	-0.6	-0.8
Delta time to tail flick, vehicle, before/after SA	1.1	1.1	3.2	-1.8	-1.2	-0.3	0.1	0.9
Delta time to tail flick, test, before/after SA	0.2	0.2	0.6	0.3	-0.0	0.8	0.1	-0.4
Ambulatory time before self-admin	0.7	0.7	2.3	0.7	1.5	0.3	0.6	0.7
Ambulatory time after self-admin	0.6	0.7	1.2	-0.7	0.8	-0.6	1.1	0.7
Total heroin consumption	0.1	0.1	0.5	-0.1	-0.1	0.7	0.4	0.0
Area under the delay curve	0.5	0.6	1.5	1.2	0.4	0.9	0.1	-0.6
Delay disc. indifference point, 0s delay	0.5	0.6	1.3	1.1	0.9	0.6	-0.2	-0.6
Delay disc. indifference point, 16s delay	0.1	0.1	0.2	0.4	-0.1	0.3	-0.0	-0.2
Delay disc. indifference point, 2s delay	0.3	0.3	0.8	0.6	0.2	0.9	0.5	-0.3
Delay disc. indifference point, 24s delay	0.9	0.9	2.3	0.4	-1.5	0.5	-0.9	-1.0
Delay disc. indifference point, 4s delay	0.5	0.5	1.2	0.8	1.1	0.5	0.5	-0.5
Delay disc. indifference point, 8s delay	0.6	0.6	1.2	1.0	1.1	0.1	0.6	0.4
Delay discount exponential model param	0.8	0.8	2.0	-1.4	-0.0	-1.2	0.2	0.9
Delay discount hyperbolic model param	0.6	0.6	1.6	-1.2	-0.2	-1.0	0.0	0.6
Fecal boli incidents, locomotor time 1	1.7	1.8	4.6	2.2	0.4	1.5	-0.8	-1.3
Change in fecal boli incidents, locomotor task	0.5	0.4	1.2	-1.1	-0.3	-0.4	0.7	0.5
Time >=10cm from walls, locomotor time 1	0.4	0.4	1.0	0.9	1.0	0.4	-0.2	0.3
Bouts of movement, locomotor time 1	0.2	0.2	0.6	0.4	-0.3	-0.4	-0.8	0.2
Total resting periods, locomotor time 1	0.2	0.2	0.6	0.7	-0.2	-0.1	-0.8	0.1
Rest time, locomotor task time 1	0.4	0.5	1.0	0.9	1.0	0.0	-0.0	0.9
Distance moved, locomotor task time 1	0.5	0.5	1.2	-1.1	-0.7	-0.7	-0.0	-0.5
Vertical activity count, locomotor time 1	0.2	0.2	0.3	-0.4	-0.6	-0.2	-0.5	-0.3
Time >=10cm from walls, locomotor time 2	1.2	1.3	2.6	-0.9	1.0	-1.6	0.8	1.2
Bouts of movement, locomotor time 2	0.3	0.3	1.3	-0.0	0.1	-1.2	-0.1	-0.3
Total resting periods, locomotor time 2	0.2	0.2	0.6	0.5	0.3	-0.8	-0.2	-0.4
Rest time, locomotor task time 2	2.5	2.9	9.1	1.5	3.0	-0.1	1.6	0.8
Distance moved, locomotor task time 2	1.8	2.1	5.6	-2.4	-0.8	-2.0	0.1	0.7
Vertical activity count, locomotor time 2	2.3	2.6	5.3	-2.2	-2.3	-1.1	-1.2	0.5
Weight adjusted by age	1.5	1.7	3.3	1.8	1.5	0.3	0.3	-1.5
Seeking ratio, delayed vs. immediate footshock	0.2	0.3	0.6	0.6	-0.4	0.2	-0.8	-0.2
Locomotion in novel chamber	0.7	0.9	1.8	1.3	1.3	0.5	0.5	-0.7
Locomotion in novel chamber post-restriction	0.4	0.5	1.0	0.5	-0.5	1.0	-0.2	-1.0
Progressive ratio	1.6	1.9	4.3	2.1	0.8	1.6	-0.5	-1.3
Food seeking constrained by brief footshock	1.0	1.3	3.6	-1.0	-1.3	0.3	-0.3	-1.9
Seeking ratio, punishment vs. effort	1.5	1.8	5.6	-2.4	-1.3	-1.3	0.4	-0.1
Run reversals in cocaine runway, females	0.6	0.6	1.0	0.9	0.2	-1.0	-0.8	-0.8
Run reversals in cocaine runway, males	0.3	0.3	0.6	0.6	0.8	0.2	0.5	-0.0
Latency to leave start box in cocaine runway	1.8	2.0	3.9	-1.3	1.3	-2.0	1.6	0.5
Latency to leave start box in cocaine runway, F	0.8	0.9	1.9	0.2	1.4	-1.0	1.0	-0.6
Latency to leave start box in cocaine runway, M	2.4	2.3	4.0	-2.0	0.4	-1.9	1.3	1.4
Cd content in liver	1.0	1.1	2.9	1.1	1.7	0.2	0.5	1.0
Co content in liver	0.9	1.0	3.0	1.7	0.7	1.0	-0.5	-0.5
Cu content in liver	0.0	0.1	0.2	-0.2	0.0	0.1	0.2	0.4
Fe content in liver	0.0	0.0	0.1	-0.3	0.0	-0.1	0.0	0.3
K content in liver	0.4	0.4	1.1	-0.2	0.6	0.2	1.1	0.7
Mg content in liver	2.4	2.4	4.6	-1.5	1.1	-0.9	2.2	1.8
Mn content in liver	1.6	1.8	4.7	-1.5	0.6	-0.7	2.2	1.0
Na content in liver	0.5	0.6	1.4	-0.0	1.0	-0.0	1.2	0.7
Rb content in liver	0.5	0.7	1.7	-0.3	1.2	0.1	1.3	0.4
Se content in liver	1.1	1.4	3.9	1.0	2.0	0.1	1.2	0.7
Sr content in liver	0.8	0.7	1.2	0.7	-0.8	0.4	-1.1	-1.1
Zn content in liver	0.7	0.8	1.7	0.9	1.3	0.7	0.8	0.3